ライフサイエンスコーパス: widen

1 continuously recruited to the pores as they widen.

2 e A/T and G/C regions where the minor groove widens.

3 l leaks/gaps formed, and intervillous spaces widened.

4 e decreased from 42% to 29%, sex disparities widened.

5 cline, but state and racial disparities have widened.

6 age at first presentation with heart failure widened.

7 esence of retinopathy and/or retinal venular widening.

8 ascular resistance consistent with capillary widening.

9 anner and demarcated by general minor groove widening.

10 ion is increasing and disease boundaries are widening.

11 een social groups with inequalities actually widening.

12 ith retinal arteriolar narrowing and venular widening.

13 rigin works at TEM boundaries to limit their widening.

14 ved structures, and, eventually, fusion pore widening.

15 of HPV vaccination in England will initially widen a pre-existing disparity in the incidence of HPV-r

16 ctive site residues, the structures reveal a widened active site cavity near the nucleobase moiety co

17 mechanics, as indicated by greater neuropore widening after ablation.

18 The groove widening aids the approach of, and the jump to, a new wa

19 erial potency the selectivity index could be widened, allowing use of lower non-cytotoxic doses.

20 anoscale particles have been incorporated to widen and diversify the scope of the light-driven liquid

21 hose for breast cancer screening appeared to widen and were 35% lower in 2009.

22 Transmission electron microscopy identified widened and distorted desmosomes in the ARVC-hiPSC-CMs.

23 linked collagens, and fibrotic septae showed widening and collagen fibrils splitting, reminiscent of

24 ipital cortices, in which significant sulcal widening and decreased sulcal depth co-occurred.

25 ten the vertical cell cross-section, thereby widening and flattening the nucleus, and the resistance

26 century health-poverty trap and the further widening and hardening of socioeconomic inequalities in

27 sulted in significant anterior chamber angle widening and increased anterior chamber area.

28 een tobacco promotion and tobacco control is widening and tobacco control may be losing ground to tob

29 way of tailoring the blazing operation, for widening and/or controlling of blazing bandwidth and inc

30 uring cell expansion, the plasmodesmata pore widens and the two membranes separate, leaving a cytosol

31 ridges, such that these structures lengthen, widen, and change position in response to traffic levels

32 ve medicine focus, signifying the growth and widening appeal of this emerging sector.

33 research has shown that skull deepening and widening are major evolutionary patterns in convergent b

34 ession analyses, greater postoperative angle widening as defined by change in AOD750 was associated w

35 The impact of twisted light is widening as recent numerical calculations provided solut

36 phous and crystalline polymer due to bandgap widening associated primarily with changes in polymer co

37 in two coupled instabilities: first, valleys widen at the expense of their smaller neighbours, and se

38 .1 mm) were significant predictors of AOD500 widening at 6 months.

39 0% from baseline along with inadequate angle widening at the month 1 or month 3 visit.

40 CG findings consisting of ST changes and QRS widening before arrhythmia onset, which have not been pr

41 even more important as our analytical focus widens beyond coding exons.

42 tamate tail of THF remains weakly bound in a widened binding cleft.

43 DeltaE2)) in 129 sv mice results in QRS, QTc widening, bundle block and STc narrowing at 2-4 months o

44 They are widened by clustering of involatile solution impurities,

45 These select sensor applications are widened by the state-of-the-art developments in the sens

46 The greatest widening by ASOCT was observed in eyes with features mos

47 capping protein participates in stereocilia widening by preventing newly elongating actin filaments

48 e of the positive feedbacks among tidal flat widening by wave-induced marsh erosion, tidal flat deepe

49 Antagonizing VE-cadherin widened cell-cell junctions and reduced the applied shea

50 Further, increased Cdc42 activation by Gef1 widens cell diameter and alters tip curvature, counterin

51 s were used to determine predictors of angle widening (change in mean angle opening distance [AOD750]

52 esulted in deformed tooth morphogenesis with widened dental lamina.

53 capillary resistance from capillary diameter widening detected in earlier histological studies.

54 osteosclerosis with relative radiolucency of widened diaphyses.

55 and that is required for tumor growth would widen disease indications and prevent immune escape caus

56 Widening disease definitions and the move from a disease

57 Social determinants have created widening disparities in end-of-life care.

58 concluded that the pores were not static but widened dramatically to release molecules of different s

59 The applicability of these IAP would be widened drastically by increasing their energy.

60 Widening economic inequality in the USA has been accompa

61 h aqueous or non-aqueous electrolyte enables widened electrochemical potential window thus may provid

62 Hoepner LA, Whyatt RM, Widen EM, Hassoun A, Oberfield SE, Mueller NT, Diaz D, C

63 whereas emission reductions from ships would widen existing population inequalities.

64 ace fields may be a consequence of spatially widened firing upon a single crossing of a place field,

65 e racial difference in survival has actually widened for acute myeloid leukemia and neuroblastoma.

66 th undetectable HCV RNA, and this difference widened for later on-treatment timepoints.

67 the point of rupture, promoting fusion pore widening for RNP release.

68 fusion KT biopsies by counting the number of widened FP per capillary loop.

69 privation gap in five year relative survival widened from -4.76 in 1991-1996 to -10.08 in 2003-2007.

70 and highest life expectancies and HALE have widened, from 2.5 to 3.1 years and from 2.3 to 2.7 years

71 rotein functions are essential to bridge the widening function annotation gap especially since <1.0%

72 The widening function annotation gap in protein databases an

73 These differences may widen further, with more extensive pediatric uptake of h

74 Patients with cancer face an ever-widening gap between the exponential rate at which techn

75 African-American women could correspond to a widening gap in actual health outcomes.

76 Infants in all three clinical groups had a widening gap in scores from the no-exposure group at day

77 This diversity, in turn, contributes to a widening gap or differences in levels of maternal mortal

78 The widening gap reported between birth weights of babies bo

79 Widening gaps in adolescent health could predict future

80 Widening geographic disparities, as measured by percent

81 dengue fever (chi(2)=135.9, p<0.001); and a widening geographic range of acquisition of chikungunya

82 erage global incomes roughly 23% by 2100 and widening global income inequality, relative to scenarios

83 nfections affect millions of individuals and widen health disparities.

84 smoking cessation services, contributing to widening health inequalities and reduced life expectancy

85 ent error, the HRs increased and the 95% CIs widened [HR = 1.19 (95% CI: 1.02, 1.39) for BS and HR =

86 e kin and that this gap in availability will widen in the coming decades.

87 cytosolic constriction for Cl(-) passage is widened in CLC-K such that the kinetic barrier previousl

88 s lived in full health, as measured by HALE, widened in several states.

89 uction speed that accompanies the axon shaft widening induced by high-frequency AP firing.

90 child mortality and undernutrition has seen widening inequities and a concentration of child deaths

91 expanding hemifusion diaphragm, and fissure widening initiating pore formation in a hemifusion diaph

92 e and CD1a-negative palisading granulomas in widened interlobular fibrous septa were detected.

93 support this model, we have shown that cell widening is abrogated in growth conditions that promote

94 ological experiments suggest that this event widening is attributable to a delayed IP3R-mediated rele

95 thin a hydrophobic "neck" of the pore, which widen it, cause the channel to be constitutively active,

96 ring a confined space, and they dramatically widened it within dozens of milliseconds when flying tow

97 he implementation of GTD, which will further widen its clinical application.

98 EBM needs to widen its scope beyond drugs and devices to address many

99 ine dinucleotide generation has considerably widened its potential biological activities.

100 Biocatalysis has widened its scope and relevance since new molecular tool

101 ealth and social policies are needed to curb widening life expectancy inequalities, help deprived dis

102 al sensor and 50 cells/mL for QCM sensor), a widened logarithmic range of detection (i.e., 3-7 for pi

103 ments have A-form C3' endo sugar puckers but widened major groove widths, giving the RNA an overall a

104 to be part of a helix with an exceptionally widened major groove, while the lariat-forming A48 is lo

105 without mental health problems significantly widened (odds ratio: 1.12, 95% confidence interval: 1.03

106 ing deformations in the steps of fusion are: widening of a hydrophobic fissure in bilayers for stalk

107 Phosphorylation of Ser65 results in widening of a newly defined cleft and dissociation of th

108 r adjusting for covariates, the magnitude of widening of AOD500 was not associated significantly with

109 Age-related widening of cPP is driven in large part by an increase i

110 ependence of susceptibility, the substantial widening of dielectric spectrum on cooling and the resul

111 ur study species resulted predominantly in a widening of habitat associations under climate change.

112 Finally, alongside protracted conflicts, widening of health and socioeconomic inequalities betwee

113 new hypomethylated regions and by extensive widening of hypomethylated intervals in ancestral specie

114 Biopsies also showed widening of intercellular spaces (confirmed by CLE), and

115 Transmission electron microscopy revealed widening of intercellular spaces with chromatin condensa

116 e skin, and result in desmosome aggregation, widening of intercellular spaces, and lipid secretory de

117 A widening of its focus to understand better the interconn

118 ction, decrease in capillary tortuosity, and widening of microvessel diameter.

119 RNFL progression patterns were observed: (1) widening of RNFL defects (24 eyes, 85.7%), (2) deepening

120 defects (2 eyes, 7.1%, both had concomitant widening of RNFL defects), and (3) development of new RN

121 n driven largely by soaring top incomes, the widening of survival inequalities has occurred lower in

122 Widening of the angle opening distance (AOD) 500 mum fro

123 itzerland, and the United Kingdom revealed a widening of the annual fruiting season in all countries

124 arteriopathy characterized by elongation and widening of the arteries and disturbance of the laminar

125 reduction of latent inhibition, resulting in widening of the associative network and enriched diverge

126 gradual vascular dilatation (p = 0.000), and widening of the bifurcating angle (p = 0.000) with incre

127 sively in the PB1 binding pocket including a widening of the binding groove and the unfolding of a be

128 how that there is considerable evidence of a widening of the BMI distribution in populations over tim

129 phological changes of endothelial cells, and widening of the cell-cell junctions, suggesting that upt

130 ces intermolecular interactions and causes a widening of the energy bands.

131 The structural widening of the extracellular vestibule is directly coup

132 d pressure in the right atrium may result in widening of the foramen and consequently, cause serious

133 he proximodistal shortening of the snout and widening of the hard palate is common to brachycephalic

134 on of the central BN core induces a dramatic widening of the HOMO-LUMO gap and an enhancement of the

135 plate cells fail to constrict, resulting in widening of the neural plate midline and defective neura

136 on of both Caspr and Caspr2 also resulted in widening of the nodes of Ranvier, suggesting that Caspr2

137 f 194 eyes, 45.4%) ERMs were associated with widening of the outer nuclear layer and loss of the fove

138 ) ion in the selectivity filter controls the widening of the pore as shown in crystal structures and

139 the pelvis taken six months before showed a widening of the proximal right femoral physis.

140 ain radiograph in frog leg position showed a widening of the right proximal physis below the right fe

141 Later deepening and widening of the South Atlantic, together with gateway op

142 treated tumors appeared less condensed with widening of the stromal areas which increased at 48 and

143 ropics and subtropics, in conjunction with a widening of the subsiding branches of the HC, resulting

144 rm tracks and subtropical dry zones and to a widening of the tropical belt ("dynamic" changes).

145 in ethnic minorities, we predict an initial widening of this gap, with cervical cancer incidence in

146 stosis of craniofacial bones and metaphyseal widening of tubular bones.

147 Laser peripheral iridotomy resulted in angle widening on ASOCT with significant increases in AOD750,

148 ostic strategy as a rational approach to the widening opportunities for the use of phenotype-targeted

149 diagnosis, which is a prerequisite for using widening options of personalized therapy.

150 s consistency in promoting root lengthening, widening or apical closure.

151 ncrease in specific adjustments of the arms (widening or raising) and legs (stiffening and extending

152 ledge gaps in this area has the potential to widen our comprehension of immune homeostasis.

153 gh performance computing, have significantly widened our analytical window and have enabled increasin

154 It widens our knowledge on the enzyme diversity world and d

155 This study widens our understanding on the mechanisms for metalloen

156 tely 100 m incision; and approximately 160 m widening over 6 years) principally through fluvial pluck

157 unctions (TJs), down-regulation of which may widen paracellular spaces between cells, allowing greate

158 nique biomedical science education centre, a widening participation and outreach project in London's

159 The present report reinforces the widening pathologic spectrum of trichomonads in humans,

160 We combined data of widened periapical spaces (WPSs) and apical rarefactions

161 neral density, abnormal dentin architecture, widened predentin and irregular predentin-dentin boundar

162 functional class II or III heart failure and widened QRS.

163 Genome-scale models are used for an ever-widening range of applications.

164 ing worm-derived immunotherapies for an ever-widening range of inflammatory diseases, including, for

165 training has more recently been applied to a widening range of neuropsychiatric illnesses, including

166 There is a widening range of tests available for detecting pathogen

167 pic closure in Taung is necessary because of widening (reorganization) of the prefrontal or frontal c

168 Nonleaky stalk expansion (stalk widening) requires the formation of a critical trans-lea

169 ls increased over time for males, suggesting widening rural-urban disparities (1996-1998: adjusted in

170 esults in significant anterior chamber angle widening seen on both ASOCT and gonioscopy, although som

171 s a significant age-by-sex effect leading to widening separation in brain sizes with age between male

172 inputs, the window of coincidence detection widened significantly with increasing gNa, indicating th

173 Histologic examination demonstrated widened sinusoidal spaces that progressively filled with

174 ble to evolving hemorrhagic infiltration via widened sinusoids.

175 Integrating this apex geometry with a widening slope, analogous to cactus spines, directly cou

176 s, and the gap between S2 and S5 is slightly widened so that the inhibitor can bind between them.

177 Presynaptic mitochondrial cristae were widened, suggesting a sustained energy demand.

178 stration was associated with alveolar septal widening, suggestive of interstitial matrix modification

179 revealed mild craniodorsal cerebellar sulci widening, supportive of cerebellar atrophy.

180 pyramidal neurons revealed action potential widening that could account for enhanced neurotransmitte

181 These data widen the allosteric and pharmacological landscape of NM

182 brane via non-endocytic pathways, which will widen the applicability to a variety of plant cells.

183 in the intensity of these molecular ions to widen the application of SIMS.

184 ase transformation that has the potential to widen the application window of Ti alloys, the most impo

185 er levels of Sr alloyed into the PbTe matrix widen the bandgap and create convergence of the two vale

186 Our results widen the basis for comparative studies of the vertebrat

187 eld of view, and on the other hand, it could widen the beam to increase the space that it senses.

188 tal assay time of 27min, which can hopefully widen the detection window for Zika viremia and is there

189 Elevated atmospheric CO2 may widen the disparity in protein intake within countries,

190 ass of colloidal materials that will further widen the functionality and properties of Janus particle

191 t structural step enables us to considerably widen the gap of possibilities in drug delivery systems.

192 stantially expand statin recommendations and widen the gap of statin underutilization in all groups.

193 ation from the second trimester onward would widen the immunization opportunity window and could impr

194 ses identified but not yet characterized may widen the landscape of possible target sequences.

195 ntrol system whereby actin waves transiently widen the neurite shaft to allow increased microtubule p

196 on which catalyst or reagent is chosen would widen the possible structures one could obtain.

197 kinetic information obtainable using DGT and widen the range of considered complex labilities.

198 his paper, we demonstrate the possibility to widen the range of in-vitro IRMS experiments to vibratio

199 ange of indications for peritoneal dialysis, widen the range of indications for CRRT, make the use of

200 Our results widen the repertoire of cellular targets for 53BP1 and s

201 emPowERment index (SWPER), has potential to widen the research on women's empowerment and to give a

202 Our results widen the scope of Mobius aromaticity dramatically and o

203 and microspheres self-aligned to them, could widen the scope of soft material-based microdevice techn

204 utic potential and novel modes of action, to widen the scope of treatment and to overcome emerging dr

205 Cd47 over endogenous human CD47 should also widen the spectrum of immunodeficient mouse strains suit

206 in a network of regulatory ATPases that may widen the substrate spectrum of proteasomal protein degr

207 many cancer settings, general strategies to widen the therapeutic window between normal tissue toxic

208 se of iRGD coadministration as a strategy to widen the therapeutic window for HCC chemotherapy, as mo

209 advent of novel treatment strategies to help widen the therapeutic window for patients with oligometa

210 iers in the tumor microenvironment to safely widen the therapeutic window of a nanoformulated cytotox

211 re oral DAC extended DAC absorption time and widened the concentration-time profile, increasing the e

212 In addition, warming of this region has widened the gap between goose migration timing and plant

213 As convergence thickened and widened the Himalaya, the orographic barrier to precipit

214 Using this pipeline, we have widened the known antimicrobial spectrum for V. odorata

215 rn of the pericystic network of vessels, and widened the large lymphatics in Pkd1(nl/nl) mice.

216 4 and +682 per thousand, which significantly widened the range of manufactured TCE delta(2)H signatur

217 We have, therefore, widened the scope of analysis to include in vitro-induce

218 The development of deep sequencing has widened the scope of genetic analysis to reveal the role

219 lled polymerisation techniques significantly widened the scope of polypeptide building blocks in a va

220 ed important insights into RNA structure and widened the scope of RNA studies.

221 ignificantly shorter reaction times and also widened the scope of the reaction to permit the use of a

222 as in fundamental soft condensed matter, by widening the accessibility of target regions in the phas

223 ncing, dedicated efforts are needed to avoid widening the already pervasive gap in health care dispar

224 d relatively hydrophilic polymeric molecules widening the applicability of the simple and cost-effect

225 Widening the availability of bariatric surgery could lea

226 esidues present in B. subtilis RNase Z, thus widening the channel and increasing its flexibility.

227 not impair bone marrow engraftment, thereby widening the clinical potential of experimental protocol

228 For widening the color spectrum and their usage, various bet

229 of cases with pure frontotemporal dementia, widening the concept of familial amyotrophic lateral scl

230 st range of risk for warfarin complications, widening the floor ceiling effects that limit the use of

231 atista movement of Chiapas, and we recommend widening the hypothesis space to include these alternati

232 minor- and the major-groove sides of G3*U70, widening the major groove.

233 embrane, displacing the paranodal myelin and widening the nodal gap.

234 density, excitonic species become dominant, widening the perspective of this material for a host of

235 s, leading to more effective coagulation and widening the pH range of water treatment.

236 ore-lining helices effect channel opening by widening the pore asymmetrically and increasing its pola

237 and 3+ oxidation states, thus significantly widening the possible combinations of metals to replace

238 or adipocyte and energy expenditure biology, widening the potential of genetically supported therapeu

239 vity is capable of functioning in vivo, thus widening the potential role of this enzyme in E. coli.

240 tween light- and heavy-hole valence bands by widening the principal band gap, which also results in a

241 positive end-expiratory pressure, in view of widening the range of cardiac index:central venous press

242 early stages of drug discovery, whilst also widening the range of communities participating in the p

243 nd reduced cooperativity of the process thus widening the response window.

244 y on 3-alkyl/aryl 2-oxindols as well thereby widening the scope even further.

245 ions in analogy to the Fenton reaction, thus widening the scope of electrochemistry in protein and pe

246 y care clinicians has prompted discussion of widening the scope of practice for mid-level providers.

247 It would be prudent to temper widening the scope of practice of mid-level providers by

248 ng the molecular pathway of epileptogenesis, widening the spectrum of possible therapeutic targets.

249 of amides catalyzed by N-hydroxyphthalimide, widening the synthetic versatility of this process.

250 Thus, the movement of one dynamic domain widens the active site entrance, while another domain ac

251 ive transformations were investigated, which widens the applicability of the pyrrolidn-2-ones as ster

252 Neuroadaptive technology significantly widens the communication bottleneck and has the potentia

253 This study widens the current structural information on ChR2 and ca

254 While the formation of interphases widens the electrochemical window, their electronic and

255 ibility, or reduced configurational entropy, widens the free energy gap between the unfolded and fold

256 ve step in in vivo imaging and analysis that widens the optical imaging window to the near-infrared s

257 m/dementia with subclinical optic neuropathy widens the phenotypic spectrum of OPA1 mutations, highli

258 low H2 concentration and short growth times widens the possibility of industrial mass production.

259 ntum dot material combinations and therefore widens the possible designs for photoelectrochemical ene

260 f the repulsive exponent in the LJ potential widens the range of applicability and accuracy of MD sim

261 This greatly widens the range of applications for the cryogenically 3

262 ecognized BCR-ABL-STAT5-IRF-8 network, which widens the repertoire of potentially new anti-CML target

263 be different from those involved in severity widens the scope of asthma genetics.

264 hed that the use of derivatization reactions widens the scope of targeted molecules but also clearly

265 F-kappaB-mediated therapeutic resistance and widens the spectrum of cancers in which these agents may

266 we demonstrate that neonatal surgical injury widens the timing window during which correlated presyna

267 lar structures with spontaneous polarization widens the utility of facile supramolecular chemistry.

268 actions at elevated temperatures, which also widens the window of application to resins that are waxy

269 Mg(2+) incorporation widens the ZnO gap by raising the conduction-band potent

270 es should be incorporated into such tools to widen their appeal and improve their usability.

271 aterials could improve their versatility and widen their applicability in electronics and sensing.

272 sing, nanomedicine, and smart materials will widen their application.

273 When close to prey, porpoises actively widen their sonar beam, which may make it harder for the

274 The remaining ant species widened their diet breadth in a way that maintained seed

275 bservant tended to have community roles that widened their social contact: religion did not aid isola

276 host response with a view to optimizing and widening their applications in higher organisms.

277 These programmes are now widening their reach to cover a broader range of childre

278 b, as negative modulators of the Hh pathway, widens their application in the context of NSCLC.

279 transcriptional amplification mechanism that widens their selective responses to low IL-2.

280 on of vestibular stereocilia and irregularly widened them.

281 As immunometabolic adjuvants to widen therapeutic windows, IDO inhibitors may leverage n

282 were apparent very early in life and did not widen thereafter.

283 STN stimulation reduced bradykinesia and widened this range in all patients, but did not restore

284 template removal can be used to achieve pore widening; this treatment is also beneficial for the mult

285 significantly attenuated as a result of the widened transarteriolar diffusion distance.

286 stable and narrow fusion pore may reversibly widen (transient exocytosis) or fully open (full-fusion

287 l4a3 KO and Col4a3;Tsp1 DKO mice exhibited a widened tubulointerstitium, predominant lesions in Col4a

288 equally increased neuronal activity, but it widened tuning curves and decreased the direction discri

289 a and subsequent outcomes in England to help widen understanding for the global burden of hospitalisa

290 ociated with higher fracture risk because of widened, unstable bones, independently of BMD.

291 r neighbours, and second, side slopes of the widening valleys become susceptible to channel incision.

292 Globally, sulcal widening was associated with cortical thinning and, for

293 ield decreases, its probability distribution widens, while the temperature of the environment remains

294 ffluent areas, but these inequalities do not widen with advancing age.

295 d human fetal muscle myofibrils elongate and widen with age, but features such as the M-line and Z-ba

296 nger than LTL and the LTL-MTLA gap similarly widened with age in ASCVD patients and controls.

297 7 for men and from 2.3 to 4.0 for women) and widened with successive birth cohorts, particularly for

298 LPI resulted in angle widening with a significant increase in opening distance

299 ard testing procedures, with the discrepancy widening with increasing missingness in the proportions.

300 disparities in the youngest children may be widening, yet efforts to translate advances in science a