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1 step in ethylene biosynthesis compared with wild type.
2 ut 10(-9.0) m produced the same effect as in wild type.
3 silencing as direct transformation into the wild type.
4 xpress mCherry, which distinguishes from the wild type.
5 nt was more susceptible to NaCl than was the wild type.
6 r brief bouts of activity and sleep than the wild-types.
8 gineered strain with a strain containing the wild-type ACT1 promoter.Genetic isolation of a genetical
9 ated by examining the effect of E6APC820A on wild-type activity and single-turnover pulse-chase kinet
10 sponse to ischemic stress that is similar to wild-type aged hearts (i.e., impaired ischemic AMPK acti
13 putative Wag31 target demonstrated that the wild-type allele was dominant and showed no synergy with
14 7) or a low ratio (0.05 to 0.7) of mutant to wild-type alleles (ITD [high] and ITD [low], respectivel
15 pha-synuclein overexpressing model harboring wild-type alleles of GBA, A53T-SNCA mouse model) were ex
16 llen and associated food allergies, a single wild-type allergen does not provide a complete solution.
20 Finally, we showed that overexpression of wild type and mutant 4R-Tau isoform in neuroblastoma SH-
22 some EBV-associated cancers, p53 tends to be wild type and overly expressed; however, the effects of
23 displays a hyperactive phenotype relative to wild type and overproduces a number of compound families
24 itro, however, IFN-gamma production by naive wild type and tristetraprolin-deficient CD8(+) T-cells i
25 study of both cancer-bearing mouse models in wild types and their corresponding control types, emphas
26 nt cluster analyses of microarray data using wild-type and c-Jun-deleted macrophages highlight the ce
28 on Ca(2+) imaging in hippocampal area CA1 of wild-type and Df(16)A(+/-) mice, an animal model of 22q1
31 ing GCaMP6s, we found no differences between wild-type and Fmr1 KO mice in overall whisker-evoked act
32 ucleus accumbens (NAc) shell ensembles using wild-type and Fos-GFP mice, which express green fluoresc
39 essing no MECP2 (MECP2-KO), congenic pair of wild-type and mutant RTT patient-specific induced plurip
41 We transfected HEK293T cells with pyrin and wild-type and mutated WDR1 Mutant protein formed aggrega
42 ed Huh7 cell lines which ectopically express wild-type and NEDDylation-deficient HBx and found that N
46 and proteomes of primary mouse B cells from wild-type and STAT6-deficient mice cultured for 4 d in t
47 o infection of gastric epithelial cells with wild-type and VacA-deficient H. pylori strains, treatmen
48 ted isolated intestinal tissue from C57BL/6 (wild-type) and Cftr(-/-) mice in Ussing chambers and mea
49 more physiological excitation rates than the wild-type, and the generation of early-after-depolarisat
50 ytokeratin-19-positive cells in the liver of wild-type animals was slightly reduced in Nlrp3(-/-) mic
56 it was suboptimal compared with that seen in wild-type bone marrow (BM)-transplanted OS mice in perip
58 embryonic fibroblasts by reconstitution with wild-type but not mutant FKBP65 that lacks intact PPIase
59 fects were reversed upon reconstitution with wild-type, but not enzyme-active site-deficient DHHC3.
62 ld-type samples were correctly classified as wild type by this method with the remaining three sample
70 acterize the magnetosome arrangement in both wild-type cells and DeltamamJ mutants, which exhibit dif
72 athways in the stem cell compartment and how wild-type cells limit the proliferation of mutant cells
73 ial drug susceptibilities of KRAS mutant and wild-type cells, and predict relapse based on increased
77 ration curve shifted to the left relative to wild type channels and the ICl was nearly insensitive to
78 gnificantly less MHCII, and grew faster than wild-type clones in s.c. and orthotopic xenograft models
87 ells proliferate more efficiently than their wild-type counterparts in response to BCR cross-linking.
88 n cryo electron microscopy (cryo-EM) maps of wild type CPMV containing RNA-2, and of naturally-formed
92 C1-64 on the plasma membrane distribution of wild-type DAT and two non-functional DAT mutants, R60A a
94 pression and activity of TACE were lower, in wild-type DCs (wtDCs) than in TNF knockout (TNFko) DCs.
95 igated the VtE-induced amelioration of DN in wild-type (DGKalpha(+/+)) and DGKalpha-deficient (DGKalp
97 genotype followed by introgression into the wild type does not result in the same level of silencing
99 grik1-2 grik2-1) that grows similarly to the wild-type, enabling us to evaluate the function of GRIKs
101 d ligand binding affinity, compared with the wild-type enzyme, demonstrating that substrate binding t
102 etic complementation of patient's cells with wild-type FANCM improved their resistance to MMC re-esta
105 dominant negative effect on the function of wild-type FLCN in regulating kidney cell proliferation a
107 and for the intermediate risk genotype NPM1 wild-type/FLT3 without internal-tandem duplications (EFS
110 % increase in fusion compared to that of the wild-type gBcyt while arginine substitutions had wild-ty
111 ress this deficit, we generated samples of a wild-type GPCR (A2AR) that are deuterated apart from (1)
112 (line M20) injected in the hippocampus with wild-type, H50Q, G51D or A53E alphaS fibrils displayed i
113 ently detected by antibodies elicited by the wild-type HA from viruses selected as the vaccine candid
114 cid (DHA), a representative omega-3 PUFA, in wild type hairless mice induced expression of the Nrf2 t
116 is the first detailed case report suggesting wild-type HIV-1 infection despite good adherence, eviden
117 remarkably reduced compared with that of the wild type, however, the mRNA levels of the wild-type and
124 have led to a SLO3 variant that differs from wild type in both pH and intracellular Ca(2+) sensitivit
125 ed currents that inactivate more slowly than wild type, indicating that increased cation permeability
127 hree orders of magnitude for the full-length wild-type KcsA, a pH-gated bacterial channel, in membran
129 yzing the expression of pRGA::GFP-RGA in the wild-type Landsberg erecta background, we demonstrate th
130 e in Flower-deficient CTLs and is rescued to wild-type level by reintroducing Flower or by raising ex
131 in animals with striatopallidal knock-out to wild-type levels, suggesting a dependence on adenosine r
132 -type gBcyt while arginine substitutions had wild-type-like fusion levels in an in vitro gB/gH-gL cel
138 lative to the sensor electrode prepared from wild-type M13, Y3E peptides engineered M13 and without M
140 sult stems from local obstruction of flow by wild-type matrix producers, which generates regions of n
144 observed in cortical pyramidal neurons from wild type mice was conspicuously reduced in TASK(-/-) mi
145 nce distribution was estimated in 8-week-old wild type mice, and stochastically varied for each condi
148 amin D) each increased serum FGF23 levels in wild-type mice and in mice with global deficiency of the
150 Kalpha2(DeltaMC) mice was lower than that in wild-type mice despite being higher after 24 hours.
151 he differential CT responses in IgA(-/-) and wild-type mice disappeared after intestinal microbiota e
154 eosinophils from fungal allergen-challenged wild-type mice maintain a distinct cytokine profile, and
159 not observed in Ig-treated Rag1(-/-) mice or wild-type mice treated with anti-type I IFNR alone.
161 ly, both the renal injury and dysfunction in wild-type mice undergoing iAKI is significantly ameliora
162 knock-out and heterozygous mice compared to wild-type mice using RNA-seq; and (iii) morphological an
163 ally, the administration of exogenous NGF to wild-type mice was found to significantly increase load-
164 nia, we found that goal-oriented learning in wild-type mice was supported by stable spatial maps and
165 monas species directly impair wound healing, wild-type mice were infected with Pseudomonas aeruginosa
166 toward either M1 or M2 macrophages in vivo, wild-type mice were injected with gamma interferon (IFN-
167 [KO]), iNOS-deficient (iNOS KO), and C57BL/6 wild-type mice were orally infected with A. actinomycete
168 was significantly reduced after treatment of wild-type mice with CSP, and uPA-deficient mice were unr
170 ing the peripheral macrophage populations of wild-type mice with Nrp1-depleted bone marrow-derived ma
171 mage at doses that caused minimal effects in wild-type mice, and adoptive transfer of gammadelta T ce
172 lanar cell polarity genes Vangl2 and Ptk7 In wild-type mice, collagen-fibril bundles appear within a
174 nificantly decreased on pressure overload in wild-type mice, paralleling a decreased oxidative metabo
176 expression caused no significant changes in wild-type mice, suggesting that Hjv is not a limiting fa
178 V-Cre, and in NBQX- and rapamycin-pretreated wild-type mice, these compounds blocking alpha-amino-3-h
179 lso sufficient to improve these behaviors in wild-type mice, when circulating levels of OCN decline a
191 ofoundly reduced rapid eye movement sleep in wild-type mice; these effects were eliminated in Taar1 k
196 study, Calhm1 knockout, Panx1 knockout, and wild-type mouse nasal septal epithelial cells were grown
197 levels of MT1-MMP were engineered to express wild-type MT1-MMP, a phosphomimetic mutant (T567E), or a
198 eport the first successful transformation of wild-type NCCs into NBL by enforced expression of N-Myc,
200 doplasmic reticulum (ER) stress in both KRAS wild-type normal pancreas cells, as well as in KRAS muta
202 ation, and CD44-null as well as HA-disrupted wild type NSCs demonstrate delayed neuronal differentiat
204 and postnatal n-6/n-3 PUFA ratio exposure in wild-type offspring under standard maternal dietary fat
206 that in glioma cells expressing either EGFR wild type or the mutant EGFRvIII, EGFR inhibition trigge
207 rated transgenic zebrafish models expressing wild-type or A152T-tau, where A152T caused neurodegenera
211 Primary cultures of hepatocytes derived from wild-type or hepatocyte-specific furin, PC5/6, or comple
214 a conditional AP2-G knockdown line and NF54 wild-type parasites at multiple stages of development, w
215 rization in Cox4i2(-/-) PASMCs compared with wild-type PASMCs, which could be normalized by the appli
219 ause 78% of human MPNSTs have expression of wild-type PDGFRA, whereas only 5% harbor activating muta
220 afish embryos overexpressing mutant, but not wild-type, PDGFRA, suggesting a mechanism through which
221 rotron-based in vivo imaging technique, that wild-type pigs display both a basal and a Toll-like rece
223 getative SAM In agreement, SP-overexpressing wild-type plants exhibited precocious doming of vegetati
227 e NTD equilibrium can be shifted back to its wild-type position by mutation at a secondary site with
230 f fibroblasts with a lentivirus encoding the wild-type protein partially rescued the deficiency of GP
232 econstitution of PTEN-null cells with either wild-type PTEN or a catalytically dead mutant stabilizes
234 s, subcutaneous adipose tissue in 14-day-old wild-type pups receiving low n-6/n-3 ratios had more adi
235 s similar to those for animals infected with wild-type R. typhi and develop comparable pathology and
237 orporation into DHFR and IkappaB-alpha using wild-type ribosomes, and the elaborated proteins could s
240 ed more efficiently by IFN-beta than was the wild-type S. aureus, and immunoblotting showed that IFN-
241 .9% (2786/2789, 95% CI [0.997, 1.00]) of the wild-type samples were correctly classified as wild type
244 px-mediated SAMHD1 degradation and inhibited wild-type SIVmac (simian immunodeficiency virus of macaq
246 acteria-specific (P25 CD4(+) TCR transgenic) wild-type spleen cells into sanroqueRag1(-/-) mice actua
249 rt succumbed to infection with a more recent wild-type strain, indicating that immune responses to th
252 lation-dependent mediator of the toxicity of wild-type tau and of all the FTDP-17 mutants tested.
255 cause the ohr mutant was more sensitive than wild type to 3-morpholinosydnonimine hydrochloride (SIN-
257 ly, this mutation was able to sustain 15% of wild-type transport activity, when the catalytic glutama
258 ein synthesis and abolished proliferation in wild-type tubular cells, but only reduced proliferation
260 tion at a secondary site with restoration of wild-type two-pronged binding of the UBXD1 adaptor prote
261 antly in its deprotonated form when bound to wild-type VAO, but predominantly in its protonated form
262 ors display a different behavior against the wild-type versus V27A mutant A/M2 channels, and (ii) the
263 growth of the escape mutant viruses with the wild-type virus revealed that some escape mutants posses
264 346 mutant maintains similar antigenicity to wild-type virus, opening the possibility for its use as
265 ection of cells with UnaG and infection with wild-type virus, passage of UnaG through progeny was sig
269 (irAGO8) plants but did not differ from the wild type when consuming plants silenced in AGO1 (a, b,
270 er binding to CNS synaptosomes isolated from wild type (wt) mice treated with NIR light was significa
271 sue) were found in LanCL1 knock-out, TKO and wild type (WT) mouse brains, suggesting that LanCL prote
272 plaque morphologies similar to those of the wild-type (WT) A24 Cruzeiro strain in BHK cells, and bot
277 ssion of FOXO transcription factors in three wild-type (WT) and three HD induced-pluripotent stem cel
278 Nephrotoxic serum nephritis was induced in wild-type (WT) and ubiquitin-binding deficient ABIN1[D48
279 t close in response to darkness but exhibits wild-type (WT) behaviour when exposed to abscisic acid (
280 hrombosis model, we found that compared with wild-type (WT) control and nonhematopoietic DREAM knocko
281 ice exhibited enhanced mortality compared to wild-type (WT) controls, while mice lacking the necropto
284 time corresponding to peak LCN2 induction in wild-type (WT) mice injected with LPS, Lcn2(-/-) mice ch
285 b1)-deficient and FXII-deficient mice and in wild-type (WT) mice pretreated with a PKal inhibitor pri
286 adiponectin gene knockout (Adipoq(-/-) ) and wild-type (WT) mice were crossed to produce pregnant mou
287 ressure during rest and activity compared to wild-type (WT) mice, and smaller responses to chemorecep
294 rdial infarction (PMI) HF model evaluated in wild-type (wt-PMI) and Nod1(-/-) mice (Nod1(-/-)-PMI).
295 Patients and Methods Mutation analyses (wild-type [WT] and mutant) for TP53, KRAS, and EGFR were
299 ures issued from embryos that expressed only wild-type Zeb2 (Zeb2(+/+) EPCs) or were heterozygous for
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