ライフサイエンスコーパス: wild-type strain

1 tine at significantly higher levels than the wild type strain.

2 le to increase BAFF at levels similar to the wild type strain.

3 the pat mutant reaching the spleen than the wild type strain.

4 ed disease at a similar rate of onset as the wild type strain.

5 of these matched the stress proteome of the wild type strain.

6 n MP1 and performed competitions against the wild-type strain.

7 mouse model of GAS invasive disease than the wild-type strain.

8 sitive to oxidative stress than the parental wild-type strain.

9 DeltaalgZ mutant was 40% of the level of the wild-type strain.

10 ed, showed a lower electro-activity than the wild-type strain.

11 provided protection against infection by the wild-type strain.

12 kness and biomass than those of the parental wild-type strain.

13 esent in the DeltaartA strain but not in the wild-type strain.

14 mutant strain compared to expression in the wild-type strain.

15 d more resistant to LpxC inhibitors than the wild-type strain.

16 10-fold lower in the hfq mutant than in the wild-type strain.

17 ic activity and cytotoxicity compared to the wild-type strain.

18 differences between the yfiR mutant and the wild-type strain.

19 fected on plastic surfaces compared with the wild-type strain.

20 umb to infection than mice infected with the wild-type strain.

21 decreased in the ccpE mutant relative to the wild-type strain.

22 kinetics comparable to those observed in the wild-type strain.

23 olonged carriage, exceeding even that of the wild-type strain.

24 on mutant S. exfoliatus ZD27 compared to the wild-type strain.

25 hemolytic activities similar to those of the wild-type strain.

26 cells selected for longer chains within the wild-type strain.

27 strain at nearly the same levels as from the wild-type strain.

28 an increase in chain length relative to the wild-type strain.

29 t or low ribosome content, compared with the wild-type strain.

30 y to oxidative stress similar to that of the wild-type strain.

31 as defective in colonization compared to the wild-type strain.

32 U, and reduced dissemination compared to the wild-type strain.

33 ificantly higher in mice inoculated with the wild-type strain.

34 ing acute infection when coinoculated with a wild-type strain.

35 lgt mutant were as virulent as those of the wild-type strain.

36 e also probed and compared with the parental wild-type strain.

37 rdF elevated 35-fold relative to that of the wild-type strain.

38 es of the deletion strains with the isogenic wild-type strain.

39 was increased by 11 to 16% over that of the wild-type strain.

40 tracellular concentration as compared with a wild-type strain.

41 n the CCV in cells infected with a C. jejuni wild-type strain.

42 eir co-isogenic wild type and one additional wild-type strain.

43 significant decrease in cytotoxicity of the wild-type strain.

44 ctively, was delayed compared to that of the wild-type strain.

45 deficient strain was less than it was in the wild-type strain.

46 eins is altered in comparison to that in the wild-type strain.

47 initial growth and survival relative to the wild-type strain.

48 both attachment and invasion compared to the wild-type strain.

49 tant produced less pyruvate and H2S than the wild-type strain.

50 al challenge with the B. mallei lux (CSM001) wild-type strain.

51 and SIN-1 both induced Ohr expression in the wild-type strain.

52 ration were similar compared to those of the wild-type strain.

53 higher lipid production from phenol than the wild-type strain.

54 ficantly more biomass than those formed by a wild-type strain.

55 onditions the mutant did not differ from the wild-type strain.

56 ppressor strains tested as compared with the wild-type strain.

57 ced fewer, smaller lesions compared with the wild-type strain.

58 nockout strains and patients infected with a wild-type strain.

59 sozyme and cold treatments than those of the wild-type strain.

60 notypes to a level comparable to that of the wild-type strain.

61 viability upon exposure to NO compared with wild-type strain.

62 y to initiate growth was comparable with the wild-type strain.

63 hyperplasia on day 14 postinfection than the wild-type strain.

64 lipid A moiety compared to that found in the wild-type strain.

65 cleared more efficiently, compared with the wild-type strain.

66 on capsule production when expressed in the wild-type strain.

67 ision point is present and functional in the wild-type strain.

68 pared with the black spore suspension of the wild-type strain.

69 titer when using the RARE strain versus the wild-type strain.

70 e, grows at a rate comparable to that of the wild-type strain.

71 of proteins within the complex compared to a wild-type strain.

72 survival rates comparable to those found in wild-type strains.

73 fective cheats in vivo and cannot outcompete wild-type strains.

74 d colonization of BALB/cByJ mice compared to wild-type strains.

75 n of host cells compared with their isogenic wild-type strains.

76 ntly more pyruvate in the growth medium than wild-type strains.

77 and higher Chl a/b ratio than corresponding wild-type strains.

78 el of C1q recognition when compared with the wild-type strains.

79 and higher Chl a/b ratio than corresponding wild-type strains.

80 ompared the lipidome of loa1Delta mutant and wild-type strains.

81 more trehalose under stress conditions than wild-type strains.

82 was absent in the complemented and parental wild-type strains.

83 rom human and murine macrophages compared to wild-type strains.

84 acterize the differences between vaccine and wild-type strains.

85 D-dependent mechanism that is not present in wild-type strains.

86 stant strains and decreasing transmission of wild-type strains.

87 t do not accumulate in detectable amounts in wild-type strains.

88 nsformants were similar to the corresponding wild-type strains.

89 intestinal epithelial cells compared to the wild-type strain 01/51.

90 n the Stargardt model Abca4(-/-) than in the wild type strains 129/sv and C57Bl/6.

91 ation-essential ICP4 and ICP8 genes of HSV-1 wild-type strain 17syn+ were brought under the control o

92 ia in human skin grafted SCID mice using the wild-type strain 2C4.3.

93 ase over the colocalization exhibited by the wild-type strain (8% +/- 6%).

94 A wild type strain, A/Hong Kong/1/68 (H3N2) developed resi

95 Compared to the wild-type strain, a H201R isogenic mutant strain caused

96 ess susceptible to early host clearance than wild-type strains after intravenous infection, but impai

97 Titan cell production by the wild-type strain also resulted in increased eosinophil a

98 with mif(-/-) L. major, when compared to the wild-type strain, also showed a 3-fold reduction in para

99 mately 10-fold higher when compared with the wild-type strain, although the expression levels of gene

100 dual ribosome-bound nascent chains between a wild type strain and a mutant defective in CTPD.

101 of proteins that could confer protection to wild type strain and help establish infection.

102 mes of two Caenorhabditis elegans strains, a wild-type strain and a strain containing two complex rea

103 scriptome-sequencing (RNA-seq) analysis of a wild-type strain and an isogenic fabT deletion mutant st

104 ecoded strain grows at a similar rate to the wild-type strain and does not exhibit any major growth d

105 altered expression compared to the isogenic wild-type strain and included transcriptional regulators

106 toxin (CDT) were evaluated first by using a wild-type strain and its corresponding cdtB isogenic mut

107 concentrations that gave derepression of the wild-type strain and retained sufficient ligation activi

108 lmonary inoculation of C57BL/6 mice with the wild-type strain and T3SS2 deletion mutant strains (5 x

109 ld improvement in FA titer compared with the wild-type strain and the strain carrying the uncontrolle

110 Cellular survival of three wild-type strains and a defined deletion mutant strain w

111 erleukin 8 expression was evaluated by using wild-type strains and their corresponding CdtB isogenic

112 46a1(-/-), Cyp27a1(-/-)Cyp46a1(-/-), and two wild type strains) and human brain specimens.

113 FtsH2 also interacts with FtsH3 in the wild-type strain, and a mutant depleted in FtsH3, like f

114 eater bactericidal activity than against the wild-type strain, and the IgG1 MAbs had similar or great

115 altered biofilm architecture relative to the wild-type strain, and these phenotypes were partially co

116 activation of macrophages, compared with the wild-type strain, and with delayed inflammatory stimuli

117 Wild-type strains are polymorphic for the npr-1 gene, an

118 d a higher accumulation of the drug than the wild-type strain as predicted.

119 ter membrane proteins, TraK and TraB, in the wild-type strain as well as in overexpression strains an

120 povesiculation phenotype of DeltanlpA in the wild-type strain as well as in the degP deletion strain

121 and differentiation in THP-1 cells than the wild type strain, as determined by carboxyfluorescein di

122 intracellular survival when compared with a wild-type strain, as judged by the gentamicin-protection

123 icantly attenuated virulence relative to the wild-type strain, as manifested by prolonged survival, r

124 mutant compared with those infected with the wild-type strain, as well as significantly greater expre

125 , which differs by a point mutation from the wild-type strain, assembles into straight filaments in w

126 A mutation in the batA gene of wild-type strain ATCC 23344 was found to be particularly

127 increases in intracellular C. jejuni 11168H wild-type strain bacteria were observed after 24-h cocul

128 t were very similar to those of the parental wild-type strains both in vitro and in vivo.

129 three alkaline-stable lipids present in the wild-type strain but absent from the mutant.

130 tely attenuated virulence as compared to the wild-type strain but did not significantly affect bacter

131 significantly up-regulated in the irradiated wild-type strain but not in the irradiated wdpks1 mutant

132 ed intact into the surrounding medium in the wild type strain, but not in the PG0026 mutant strains.

133 verexpressing PR1 enhanced resistance to the wild-type strain, but not to the Sscp1 knockout strain o

134 M mutant was less efficient than that by the wild-type strain, but only upon HBMEC infection.

135 strains were more sensitive to acid than the wild-type strain, but the Deltahyc strains were like the

136 d hha mutant strains compared to that in the wild-type strain, but the secretion of virulence protein

137 be almost completely restored to that of the wild-type strain by adding purified recombinant AtlA aut

138 arasite mitochondrion, even outcrossing with wild-type strains cannot facilitate spread of resistance

139 duced by ER stress, and their knockdown in a wild-type strain caused ER stress.

140 , for both classes of promoters, peak KOA in wild-type strains coincided late in the circadian cycle

141 t (Triticum aestivum) spikelets, whereas the wild-type strain colonized the whole wheat spike.

142 nt and its isogenic choline-treated parental wild-type strain D39 degrade extracellular DNA readily,

143 Compared with wild-type strain, DeltacolA mutant displayed much-attenu

144 le infectivities in the C3H/HeN mice and the wild-type strain, despite the reduction in several patho

145 n of the mazF gene does not eliminate PCD in wild-type strain DK1622 as originally seen in DZF1.

146 cells 3 to 5 times more extensively than the wild-type strain does.

147 unts of cytochromes c(1) and c(2) than did a wild-type strain due to their restricted Ccm capabilitie

148 survival equivalent to that of the isogenic wild-type strain during active tuberculosis in guinea pi

149 significantly higher than expression in the wild-type strain during exponential growth or stationary

150 Particularly, we used a wild type strain (E1162) and a mutant (E1162Deltaesp) to

151 The overall K(M) of Hn uptake by wild-type strain EGD-e was 1 nM, and it occurred at simi

152 report, we demonstrate that the majority of wild-type (strain EGDe) and mouse-adapted (InlA(m)-expre

153 In a wild-type strain, elevated levels of Hda conferred sensi

154 Compared to the wild-type strain, expression of rtx genes decreased in t

155 Similar to the wild-type strain, FLL402 and FLL403 displayed a black-pi

156 ant lacking all three genes behaved like the wild-type strain for all phenotypes mentioned above, but

157 Compared with wild-type strains for FKS1, echinocandin-resistant C. al

158 Different wild-type strains form social interaction networks with

159 the proteomes of the mutant to those of the wild-type strain further confirmed the differential expr

160 ceptible to phagocytosis by THP-1 cells than wild type strain (G37).

161 as smaller than that found between different wild-type strains grown in traditional Hutner's suppleme

162 Agrobacterium tumefaciens wild-type strain (GW4) was studied to determine how the

163 istopathologic examination revealed that the wild-type strain had a greater ability to colonize tissu

164 However, the wild-type strain had a greater advantage over the SdiA d

165 genome per generation; (ii) mutations in the wild-type strain have the expected mutational bias for G

166 lonized at a level comparable to that by the wild-type strain; however, in cocolonization experiments

167 mutants in defined competitions against the wild-type strain identified nine mutants that exhibited

168 mune responses was compared with that of the wild-type strain in a bacteremic mouse model.

169 nt mutant is less virulent than its parental wild-type strain in BALB/C mice.

170 onization, and is unable to compete with the wild-type strain in co-colonization assays.

171 8-0643, and the ure mutant was used with the wild-type strain in competition experiments in mouse mod

172 ow as well as or better than a corresponding wild-type strain in EVPL.

173 s more severe inflammation than the isogenic wild-type strain in gerbils.

174 A single gavage of C. glabrata wild-type strain in mice with DSS-induced colitis caused

175 kidneys when tested in competition with the wild-type strain in the murine model of UTI.

176 mug of human fH/ml permitted survival of the wild-type strain in up to 60% infant rat serum, whereas

177 in vivo-selected mutant grew as well as the wild-type strain in vitro.

178 he trehalose production genes to out-compete wild-type strains in mice and macrophages.

179 xpressed VPS colonized less effectively than wild-type strains in more distal intestinal regions.

180 Rapid differentiation of vaccine from wild-type strains in suspect measles cases is a valuable

181 irulence compared to the virulence of El Tor wild-type strains in the infant mouse cholera model.

182 shift in exflagellation EC50 relative to the wild-type strains in the presence of compound 1294, prov

183 to bind fibronectin relative to that of the wild-type strain; in situ reconstitution of fnm in the d

184 ced stress, and in response to H(2)O(2), the wild-type strain increases superoxide radical production

185 criptomes of an rppH deletion mutant and the wild-type strain incubated at 20 degrees C and 30 degree

186 n of the mutant phenotypes with those of the wild-type strain indicated the following: Ohr protects a

187 Comparison of the REd and wild-type strains indicates that restriction did not aff

188 uced resistance to quinolone compared to the wild-type strain, indicating that fur functions as a pos

189 rt succumbed to infection with a more recent wild-type strain, indicating that immune responses to th

190 t in cells exposed to the isogenic S. aureus wild-type strain, indicating that PSMs inhibit the produ

191 sulfate was 40-fold slower than that of the wild-type strain, indicating that the efficient uptake o

192 e highly induced under oxidative stress in a wild-type strain, indicating the critical role of Cys-25

193 lic adjustment (MOMA) from the corresponding wild-type strains instead of having maximal growth rates

194 8 deletion mutants were constructed from the wild-type strain K96243.

195 Xenorhabdicin prepared from the wild-type strain killed the potential competitor Photorh

196 ] 1.64 x 10(4) CFU) compared to the parental wild-type strain LD(50) (2.98 x 10(2) CFU).

197 howed a smaller hepcidin increase than their wild-type strain-matched controls, Bmp6(-/-) mice showed

198 ize porcine lungs and was outcompeted by the wild-type strain (median competitive index of 2 x 10(-5)

199 In the wild-type strain, MpkA phosphorylation levels progressiv

200 pression was also noticed in an M. smegmatis wild-type strain (MSWt) induced with cumene hydroperoxid

201 matode Caenorhabditis elegans, the canonical wild-type strain (N2) and a mutant strain with elevated

202 aride (LOS) of a lic2B mutant to that of the wild-type strain NT127 revealed that lic2B is required f

203 We compared the secretion profiles of a wild-type strain (NY-4) of V. parahaemolyticus with thos

204 se data indicate that murine death caused by wild-type strains occurs by a mechanism different from t

205 rain were purified and used to show that the wild-type strain of Cba. tepidum can grow on biogenic S(

206 anscript in host macrophages infected with a wild-type strain of M. tuberculosis or an attenuated mut

207 By comparing a wild-type strain of Staphylococcus aureus and a lysozyme

208 We examined the wild-type strain of Synechocystis sp. PCC 6803 and a ser

209 We examined the wild-type strain of Synechocystis sp.PCC 6803 and a seri

210 development of reverse genetics systems for wild-type strains of CDV and the use of the resulting re

211 We found that wild-type strains of fruit flies, Drosophila melanogaste

212 McKrae is highly virulent compared to other wild-type strains of HSV-1.

213 hesis after infection with vaccine than with wild-type strains of MeV.

214 th conidia (asexual spores) of two different wild-type strains of N. fumigata and three different erg

215 er, infection of guinea pigs with nonadapted wild-type strains of the different species resulted in f

216 The number of disease lesions incited by the wild-type strain on bean was also significantly higher t

217 When the wild-type strain overexpressing ecm was tested with the

218 -sigH, compared with those infected with the wild-type strain (P < .05).

219 tion by HEp-2 cells compared to the parental wild-type strain (P < 0.05).

220 mation significantly compared to that in the wild-type strain PA14 in an abiotic biofilm system.

221 howed that OMVs generated from P. aeruginosa wild-type strain PAO1 were more cytotoxic to alveolar ep

222 ts was significantly reduced compared to the wild-type strain PH-1, while 10 Group 2 mutants grew nor

223 d disease upon subsequent challenge with the wild-type strain PI1428, which appears to be driven by a

224 ection model, 1 week following infection the wild-type strain produced significantly more widespread

225 Moreover, infection due to wild-type strains produced dermonecrotic skin lesions, w

226 and BBA64 compared to those for the parental wild-type strain propagated under these conditions, whil

227 attenuated in the mouse and equine, whereas wild-type strain RacL11 induces severe inflammation of t

228 thermore, impairment of the Sec pathway in a wild-type strain reduced Ag43 production but did not sig

229 on of Cse4, transient induction of PSH1 in a wild-type strain resulted in phenotypes similar to a pat

230 in-deficient S. aureus and the corresponding wild-type strain reveal that activation of acid sphingom

231 The average genome configuration of the wild-type strain revealed strong intra- and inter-chromo

232 Transcriptome comparison of DeltascrABC and wild-type strains revealed expression differences with r

233 inst a leaky Escherichia coli strain and the wild-type strain reveals the contribution of the formida

234 1921 and CVD 1941, derived from the invasive wild-type strains S. Typhimurium I77 and S. Enteritidis

235 rs genotypically and phenotypically from the wild-type strain S26/3.

236 C. albicans wild-type strain SC5314, prototrophic mutant control DAY

237 inoculated with the formyl peptide-producing wild-type strain showed a significantly increased freque

238 observed in domesticated and undomesticated wild-type strains sporulating in liquid and on solid med

239 d increase in virulence as compared with the wild-type strain, suggesting that LOS-IV plays a role in

240 ant was still less virulent in vivo than the wild-type strain, suggesting that SecA2 function was sti

241 was observed between the luxS mutant and the wild-type strain, suggesting that the defect in virulenc

242 wed an adhesion level similar to that of the wild-type strain, suggesting that the gene does not dire

243 id not spread in tomato stems as well as the wild-type strain, suggesting that these exDNases facilit

244 e reduced binding of surface IgG compared to wild-type strains, suggesting that prior exposure to S.

245 detection of a circular form of the GGI in a wild-type strain suggests that GGI excision may occur na

246 ficient in eliminating SIC compared with the wild-type strain, terminal half-lives being 6 and 1.5 h,

247 erence to HEp-2 cells were much lower in the wild-type strain than in the hha mutant, but no signific

248 Compared with the wild-type strain, the esxH-deficient strain induced five

249 Thus, at lower epitope density in the wild-type strain, the IgG3 anti-fHbp MAbs had the greate

250 In cell extracts of the M. maripaludis wild-type strain, the specific activity of DapL using ll

251 ltasll1951 strain was similar to that of the wild-type strain, the viability of the Deltasll1951 stra

252 /Delta contained more cellular iron than the wild-type strain, their transcriptomes strongly resemble

253 ted during amino acid stress, whereas in the wild-type strain these levels declined under the same gr

254 In wild-type strains, these mismatches are repaired by the

255 can be generated through seeds by crossing a wild-type strain to a transgenic strain with altered cen

256 g1Delta mutant was less susceptible than the wild-type strain to noniron metalloporphyrins, further i

257 tants with altered biofilm formation and the wild-type strain to predict drug targets against P. aeru

258 into gnotobiotic mice together with 11 other wild-type strains to generate a 15-member artificial hum

259 h the molecular clock for VP1 of circulating wild-type strains to infer that the mean time from the i

260 In the wild-type strain, transcription of B. henselae hbpC was

261 rmed comparative genome sequence analysis of wild-type strain TX82 and TX6051 and found a single muta

262 rn mice were inoculated intramuscularly with wild-type strain type 3 Dearing (T3D) and T3D-sigma1R202

263 ntaining medium and grew slower than did the wild-type strain under aerobic and anaerobic conditions,

264 d staphyloxanthin production compared to the wild-type strain under aerobic culturing conditions.

265 hile the Deltaspx strain grew as well as the wild-type strain under anaerobic conditions, the mutant

266 development by a developmentally proficient wild-type strain under high-nutrient conditions.

267 sted that the same transcript appears in the wild-type strain under nutrient-limiting conditions.

268 resulted in the inability to compete with a wild-type strain under selective conditions that require

269 of two, ylxY and ylyA, were outcompeted by a wild-type strain under sporulation-inducing conditions,

270 nt did not attach to tomato roots as well as wild-type strain UW551.

271 Deletion of the rtfA gene in wild-type strains (veA+) resulted in a slight decrease i

272 rated in different genetic backgrounds (e.g. wild-type strain versus knockout strain).

273 lymphoid tissues and reveals the protective (wild-type strain) versus harmful (yopP-deficient strain)

274 The wild type strain was sensitive to BTZ043; however, C. gl

275 ia, diet did not affect the outcome that the wild-type strain was better able to persist and colonize

276 When the wild-type strain was grown with exogenous hydrogen perox

277 ted in static conditions, the fitness of the wild-type strain was higher under fluctuating humidity c

278 nt also failed to induce abortion, while the wild-type strain was highly abortifacient.

279 The wild-type strain was twice as likely to survive passage

280 The clinically important M1T1 wild-type strain was used in this study, and isogenic mu

281 acid-dependent growth arrest, and unlike the wild-type strain, was susceptible to fatty acid synthesi

282 data from five single gene knockouts and the wild type strain, we decrease the mean squared error of

283 ed by the Bvg(+) phase-locked mutant and the wild-type strain were indistinguishable.

284 Edmonston vaccine/laboratory and IC323 wild-type strains were equally affected by the inhibitor

285 Wild-type strains were subjected to VP1 gene sequencing

286 in this Tn library, and in various C. jejuni wild type strains, were compared and correlated to detec

287 tively, did not differ in virulence from the wild-type strain when assayed in pear fruit and apple sh

288 mutant was significantly outcompeted by the wild-type strain when birds were inoculated with a low d

289 he mutant was the same as that of the parent wild-type strain when cultured in nutrient-rich media wi

290 oteins that disrupt function in an otherwise wild-type strain when overexpressed.

291 n mice compared to the levels induced by the wild-type strain, whereas an msbB pagP mutant induced le

292 di-GMP as well as stimulates swarming in the wild-type strain, while overexpression of MotA from a pl

293 Treatment of yeast wild-type strain with 10 mM SSA and 10 mM GHB didn't aff

294 Cochallenge of the wild-type strain with an MMR-defective strain showed a s

295 ns to compare the envelope (Env) spikes of a wild-type strain with those of a mutant strain in which

296 s putida and P. aeruginosa, and compared the wild-type strains with deletion mutants for crc.

297 ed in more-severe pulmonary infection by the wild-type strain (with a 30-fold increase in the number

298 ed EmaA was reduced by 50% compared with the wild-type strain, without changes in mRNA levels.

299 mice using a virulent C. perfringens type D wild-type strain (WT), an isogenic ETX null mutant (etx

300 Clostridium thermocellum wild-type strain YS is an anaerobic, thermophilic, cellu