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1 , efficient reovirus reverse genetics rescue will accelerate production of recombinant reoviruses as
2 ify driver patterns in ovarian cancer, which will acquire some novel and clinical biomarkers for appr
3        We argue that mesic microenvironments will act as species-specific refugia only if the nature
4                                  This review will address the functions attributed to cancer exosomes
5  suggesting that environmental heterogeneity will affect large-scale Wolbachia transformations of urb
6  physical flux in natural populations, which will affect the ecology and evolution of infectious dise
7 ity to obtain full PV genomes from FTA cards will aid in facilitating global poliovirus surveillance.
8 tion of the elementary steps of this process will aid the design of new catalytic systems and their r
9 m enabled microfluidic flow-through approach will allow efficient microbial conversion of carbon-cont
10 arieties with relevance for cider production will allow for informed decision making for both apple p
11 he mechanism of long-distance iron signaling will allow improved strategies for the engineering of st
12 ere and provides an electrostatic meter that will allow local electrostatic potential and energetics
13 urgical treatment in individual patients and will allow the comparison of outcome data in future stud
14                                           It will also be important to align resources and incentives
15  to overcome resistance, but, in the future, will also be the basis for implementing precision cancer
16              Strains identified in this work will also enhance the sensitivity of C. elegans based dr
17                                           We will also examine how to craft these concepts into tools
18 hat structure variation on recent timescales will also leave similar genomic signatures that reflect
19                           This increase in N will also result in a lower S1 energy state, which may p
20 extraordinary lifestyle, and further probing will answer exciting basic microbiological and clinicall
21                          In sum, this review will argue that neural-glial interactions represent an i
22       We found that a prefusion intermediate will assemble with HOPS and the R, Qa, and Qc SNAREs, an
23                                     Last, we will assess whether evidence exists in the literature th
24                      We anticipate that this will be a valuable resource to the field of inflammation
25                 We believe that BepiPred-2.0 will be a valuable tool for the bioinformatics and immun
26 ndent genetic control suggests that breeders will be able to select semi-independently for mean pheno
27 hromboembolic pulmonary hypertension (CTEPH) will be accelerated by an animal model that replicates t
28 Our findings suggest that the new SFTS model will be an excellent resource to better understand SFTSV
29 rce to the field of inflammation biology and will be an important asset in future anti-inflammatory d
30 aching impacts on the sustainable energy and will be an important research topic in the near future.
31 e late 21st century when climatic conditions will be analogous to the most severe dry/heat spells cau
32 re the current state of knowledge of the NVU will be assessed, focusing on one of its most vital role
33 e proposed method is implemented as in R and will be available an a Bioconductor package.
34 ntly, using AWPM-SG in irrigation scheduling will be beneficial to save more water in areas with shal
35 t by Sc2.0 Consortium teams around the world will be consolidated into a single strain by "endoredupl
36                         Potentially, targets will be consumed at 1 M per day per reactor, demanding
37 -inserted state of SecA is still lacking and will be critical for elucidating the bacterial protein t
38 oses a daunting challenge for clinicians but will be critical for the success of disease-modifying th
39                             Overall response will be defined as complete response, partial response,
40  described, then individual TORCH infections will be described and compared with the imaging findings
41  findings of congenital infections initially will be described, then individual TORCH infections will
42 ommon cancer among women and 30% of patients will be diagnosed with an ErbB2-positive tumor.
43 en microbes, their metabolites, and the host will be discovered.
44  the basis of these supramolecular materials will be discussed.
45          Critical to enhancing understanding will be disentangling the relative importance of host tr
46 ctivity, therefore downstream dopamine cells will be disinhibited; and thus, this could potentially r
47 shifting from "if it can be done" to "how it will be done." Moving from a theoretical stage to this h
48               Shifts in trophic interactions will be especially important when affecting habitat-form
49 ses in both total and extreme precipitation, will be especially strong for the Northeast and the corn
50               Our flexible Bayesian approach will be especially useful to improve cross-cultural life
51       As of the beginning of 2017, providers will be evaluated on quality and in later years, cost as
52 f these challenges there is a risk that some will be exacerbated.
53                                 The resource will be extended to >1 million peptides, and all data wi
54 n treating infections caused by MDR bacteria will be heavily influenced by a precision medicine appro
55 tes that successful therapeutic intervention will be highly dependent on the specific therapeutic tar
56                                         This will be important in predicting extrusion hotspots and d
57 lecules, only sunlight and fluorescent tubes will be important to room-averaged indoor HOx levels due
58 lic vectors, existing vector control tactics will be insufficient to achieve elimination, even if max
59 tudies in atomic and molecular chains, which will be key to investigating numerous fundamental issues
60     Important allergic disorder associations will be missed without subgroup analyses.
61 recipient factors, based on local data sets, will be more beneficial in the Australian context.
62 f disease-causing host-parasite interactions will be more clearly understood through a focus on disea
63                      Significant preparation will be needed for a thorough, synchronized, and full wi
64 ovel immunotherapies and combinations likely will be needed for most subtypes.
65                              Further studies will be needed to assess possible herd immunity effects
66 95% uncertainly interval [UI], 55.2 to 60.0) will be obese at the age of 35 years, and roughly half o
67 data suggest that pheromone-based technology will be of global utility for the monitoring of this imp
68 oral multiplex networks and we anticipate it will be of interest to researchers in a broad array of f
69                                         This will be of potential use for monitoring HD mouse model d
70 sion and predicts that type I IFN modulation will be pivotal to cure human chronic infections, cancer
71 his Perspectives article, these new insights will be placed in the context of previously unresolved i
72 r results suggest that coffee-suitable areas will be reduced 73-88% by 2050 across warming scenarios,
73 h changes in terrestrial water storage (TWS) will be reflected in the water contained in the ocean an
74 perties obtained under idealized assumptions will be reported separately.
75                  International collaboration will be required to perform clinical studies to inform t
76 r from the non-permanence risk that stored C will be returned to the atmosphere.
77 ne whether this class of potential therapies will be safe and effective for individuals with retinal
78 us predict that tropical coastal communities will be seriously endangered as the global sea level ris
79 xtended to >1 million peptides, and all data will be shared with the community via ProteomicsDB and P
80 e elements with similar retention mechanisms will be similarly affected by climate change.
81 rrently subjected to warm and dry conditions will be the most vulnerable in the late 21st century whe
82                             These guidelines will be updated periodically as more evidence becomes av
83 her, these results indicate that this system will be useful for functional and gene expression studie
84                                These results will be useful for vector selection for various applicat
85 ing hydrogen sulfide, perthiol, and COS, and will be very useful as part of the toolbox for delineati
86 s by clinicians, nurses, and patients, which will be vital in ensuring viral load tests are appropria
87 ible molecular knot topologies increases, it will become increasingly useful for chemists to adopt th
88  biomarkers that predict which mRCC patients will benefit from antiangiogenic therapy.
89 history is critical to identify families who will benefit from genetic testing, determine the best st
90 on of biomarkers that predict which patients will benefit from these therapies.
91 m strategy will create a network effect that will benefit multiple disease programs.
92 lar imaging would help identify patients who will best respond to anti-PD-L1 treatment while potentia
93 hat by 2030, national female life expectancy will break the 90 year barrier, a level that was deemed
94 sses, as the consequences on their abundance will cascade throughout the food web.
95 ntial of high-performance nanomaterials that will cause disruptive improvements in the field of biose
96       Our models predict that climate change will considerably reduce establishment of a currently pr
97  chemotherapy and ongoing randomised studies will continue to aim to optimise treatment for high-risk
98      Finally a perspective on how this field will continue to evolve is provided.
99 th cohorts in diverse environments worldwide will continue to provide critical knowledge about the fa
100 study into this interesting set of compounds will continue to provide insights into fundamental quest
101                                These efforts will contribute to a more complete understanding of glob
102 ating these species instead of Norway spruce will contribute to maintaining a high level of productiv
103                                   Biosensors will contribute to the 4th revolution in agriculture by
104  on the disordered vanadium oxide nanosheets will contribute to the exploration of disordered structu
105        This Review is organized by metal and will cover work published from late 2009 until mid-2016.
106                          A platform strategy will create a network effect that will benefit multiple
107 iciency comparing several mouse models, that will deepen our understanding, open avenues for research
108                We anticipate that this study will demonstrate that idiopathic DCM has a genetic basis
109                The urgency of the transition will depend largely on the country-specific prevalence o
110                           Improving outcomes will depend on a multifaceted approach, including correc
111                     The appropriate strategy will depend on characteristics of the sample, the sequen
112   The costs associated with this legislation will depend on how actors in the food value chain respon
113 ectron spins as qubits for quantum computing will depend on the ability to produce molecules with wea
114 their effect on subsequent guideline updates will depend on the methodology and evidence model used b
115                                 This article will describe the past decade of work toward this goal a
116  and the other in late protocol development) will determine the clinical efficacy of fosfomycin as st
117    Up to one third of individuals with NAFLD will develop nonalcoholic steatohepatitis (NASH), which
118 ants encountering strong westerly crosswinds will diminish.
119 nal microbiota and the immune system, and we will discuss how a dietary-induced disruption of the int
120                           In this review, we will discuss recent progress made in the field of functi
121 sibly identifying peripheral biomarkers that will eliminate the need for scalp biopsies.
122                                     SEQSpark will empower large sequence-based epidemiological studie
123 ng numerical solutions for insolation, which will enable a more precise and accurate geological times
124                        This synthetic system will enable detailed, mechanistic dissection of MCC gene
125  model of depth-integrated, daily production will enable efficient global predictions of picophytopla
126                                    This work will enable future efforts in developing highly efficien
127      However, identifying distinct responses will enable novel routes for PTP-selective drug design,
128    The experimental techniques reported here will enable thermal transport studies in atomic and mole
129 ment of common postoperative conditions they will encounter as new surgical interns.
130 elivery could exceed US$30 billion, and this will encourage researchers to study the application of N
131 k of the desire to control when and how life will end.
132                                    The ICHOM will endeavor to achieve wide buy-in of this set and fac
133 nderstanding of this differential regulation will enhance efforts to improve oilseed rape productivit
134                      These false assignments will eventually lead to wrong conclusions on the structu
135         Building on this success, CRACKLE II will expand the network to hospitals across the United S
136                         Nearly all older men will experience lower urinary tract symptoms associated
137                               Future studies will explore methods to reduce kidney activity retention
138  models project that subalpine forest ranges will extend upslope with climate warming.
139 r convergence and building blocks of CAM and will facilitate CAM-into-C3 photosynthesis engineering t
140 ce, and analyses of treatment mediators that will facilitate further therapeutic development.
141 genetic correlation among complex traits and will facilitate future soybean functional studies and br
142                                Thus, FlpStop will facilitate investigations into the interactions bet
143 n vivo and in ex-vivo tissue sections, which will facilitate mRNA trafficking studies in pre-clinical
144 ur assembly method is readily accessible and will facilitate the construction of sophisticated materi
145 ng of the mechanism of this efficient enzyme will facilitate the development of synthetic molecular c
146 dy provides crucial insights into RIBEs, and will facilitate the identification of additional RIBE fa
147  and weaker affinity with SnI2 than FA+ ions will facilitate the intramolecular exchange with FA+ ion
148 ions occurring in close temporal proximity - will favor populations that would otherwise have an aver
149 e believe our results and simulation methods will find applications in many different contexts.
150                   In this review article, we will first review the key role of Ca(2+) in normal cardi
151                                  This review will focus on the current knowledge for the main subclas
152 ients is warranted, and as such, this review will focus on the incidence, surveillance, and treatment
153                                  This review will focus on the role of cell death in maintenance of T
154                       Whereas another review will focus on the role of Runx factors in leukemias, thi
155 pective measurements of peripouch fat, which will foster future investigation of the role of mesenter
156 the influence of early and midlife exposures will further advance our understanding of the disease.
157  diverse biological systems and tissue types will further improve our understanding of ancient DNA br
158                                  This review will give an overview of the presentation, evaluation, a
159                            An ideal observer will give equivalent weight to sources of information th
160                                This platform will greatly benefit both researchers and clinicians for
161 l phenomena is that of straightness - a root will grow down, a petal will grow flat.
162 traightness - a root will grow down, a petal will grow flat.
163 are not intended as fixed depictions of what will happen.
164 ating syndrome of the central nervous system will have a monophasic disease course, with no further c
165 s of mutation-dependent drug response, which will have a significant impact on cancer precision medic
166 imization of high-energy-storage dielectrics will have far-reaching impacts on the sustainable energy
167 t the end of the experiment some metabolites will have incorporated the labelling isotope, to a degre
168 is an example of the impact that 3D-printing will have on the future of analytical device fabrication
169  therefore hypothesized that IL-15(-/-) mice will have reduced inflammatory responses during the deve
170 at cancer cells that survive treatment still will have suffered cytotoxic stress and thereby enter a
171 ere improving the resolution of climate data will have the largest impact on the accuracy of biologic
172 Abeta1-42 level is an important finding that will have to be replicated in other cohorts.
173 to metabolite data, we hope that this system will help enable data sharing and reanalysis in the meta
174                                   This model will help further discover the pathomechanisms of this d
175                  This and similar approaches will help identify additional intermediates during CCC D
176                                These studies will help identify novel treatment strategies.
177 survival and differentiation of repair cells will help identify, and eventually correct, the failures
178 implications of distinct cell death pathways will help in the development of therapeutic intervention
179  the impact of different risk factors, which will help in understanding the development of obesity in
180                                  Our results will help permit the rational design of complex new mole
181                                   This paper will help researchers to better design spin trapping exp
182                                   These data will help to prioritize future research directions.
183                     The C5aR2 knock-in mouse will help to reliably track and conditionally delete C5a
184  This group of rare designed hexasaccharides will help understand HCII function.
185                                           We will here review key findings that have elucidated the c
186 l in predicting severity of illness but also will hopefully allow for identification of the disease p
187 elevant targets in neoplastic mast cells and will hopefully receive recognition by health authorities
188                                This research will impact our understanding of morbillivirus-related i
189 act of dehydration and electrolyte imbalance will improve health outcomes.
190 ons into FRED to fill gaps in trait coverage will improve our understanding of changes in fine-root t
191 counting for Allee effects in social species will improve our understanding of the ecological and evo
192 sociated SNPs and the regulatory genome that will improve the functional interpretation of non-coding
193 e basis for further experimental work, which will in turn provide input to refine and develop the mod
194 ation processes and implementation protocols will increase access to wireless optofluidic neural prob
195                        The hazard of dropout will increase from 41% to 46% nationally.
196 , and the median age of the NAFLD population will increase from 50 to 55 years during 2015-2030.
197 est that comprehensive WGS-based SV analyses will increase the power of common- and rare-variant asso
198 ectors are added to the ECF based cells that will increase the total weight of devices.
199 llary is that in a globalizing world, wealth will inevitably be appropriated by a very small fraction
200 HF, OFT and HM development in zebrafish that will inform mechanistic interpretations of cardiopharyng
201                                These results will inform the rational development of 2D COF polymeriz
202 g users to build intuition and insights that will inform their experimental strategy.
203 , knowing how different species' metabolisms will integrate to reach a desired outcome is a difficult
204       Interventions that target these events will interrupt tuberculosis transmission and accelerate
205 imental validation, predict that rare fixers will invade a population dominated by non-fixing bacteri
206 ey expect the diagnostic information yielded will lead to better patient care, enhanced patient safet
207                 Resolving these three issues will lead to better, more replicable, and more useful so
208  that combined, elevated CO2 and temperature will lead to long-term declines in the amount of carbon
209        Validating these associations in vivo will lead to new diagnostic tools for Alzheimer disease
210 hanisms that acutely affect DAT availability will likely exert significant impact on both normal and
211 to program therapeutic cells, so our methods will likely facilitate manufacturing of cytoreagents.Cur
212  for nonelderly Americans, private insurance will likely play a major role.
213  years with substantial care needs, and most will live in the community.
214 rated fats, especially polyunsaturated fats, will lower the incidence of CVD.
215                     Future regulatory design will minimize compliance costs and HEC tradeoffs by regu
216 nd grain filling using donors such as NL-44, will minimize the negative impact of heat stress and inc
217 f sea-level rise expected no later than 2050 will more than double the frequency of extreme water-lev
218 g programs and create new opportunities that will move us closer to the vision of achieving an oncolo
219 ven if observers are certain that the object will move.
220                 Health policy in Afghanistan will need to address attitudinal, social, and accessibil
221 ven if successful, however, these approaches will need to be combined with additional complementary a
222  taken, there are substantial obstacles that will need to be overcome if CRISPR-Cas9 is to be used in
223 ul mitigation efforts in the Red Deer region will need to focus on the >90% of methane emissions curr
224  to elevated circulating E2 Collectively, we will need to modify the concept of estrogen's positive f
225    However, extant plant trait distributions will not allow extrapolations to novel community assembl
226 ith pharmacoresistant temporal lobe epilepsy will not be rendered completely seizure-free after tempo
227 antially increased resolution of gene models will not only further our understanding of the biologica
228 detailed understanding of these interactions will not only provide improved treatment options to over
229 tion of polyadenylated RNA via oligo(dT), it will not provide RNA-binding information on proteins int
230 ge in forest or wetland biomass or soil, and will not suffer from the non-permanence risk that stored
231 ough finite temperature equilibrium dynamics will not yield hyperuniform states, driven, nonequilibri
232 nthesis of a protein to ensure that an event will occur at a precise time, while minimizing deviation
233 and roughly half of the projected prevalence will occur during childhood.
234                    Most of these extinctions will occur over an extended time, and therefore, reconne
235 patients with CVID with immune dysregulation will offer new therapeutic avenues for this subgroup.
236 ion of Oldowan zooarchaeological assemblages will only be accurately revealed by better bounding equi
237 nd their chemical versatility for adaptation will open new opportunities for applications built upon
238 s), the integrated cheminformatics algorithm will optimize the extracted biological data using in vit
239  and recent data suggest that only about 50% will outgrow by age 8.
240                MSM not attending GUM clinics will partially benefit from herd protection.
241 dy suggest these phenolic and nitro-aromatic will partition into the condensed state for a wide range
242 o increased cardiovascular (CV) risk in PTSD will pave the way for developing interventions to improv
243 unities afforded by supramolecular chemistry will play a vital role in the future of the drug deliver
244                       It is likely that TAVR will play an increasingly important role in the manageme
245 fore pain modulatory systems reach maturity, will predict pronounced changes in thalamic development,
246                                           We will present herein an overview of the interactions occu
247 te that the population of sub-Saharan Africa will probably lose 2.3 million disability-adjusted life-
248   Moving forward, answers to these questions will provide a greater level of understanding of miRNA b
249 ental concerns, we anticipate that this work will provide a standardized baseline for future work to
250              Our coherence control technique will provide a unique solution for a low-speckle, full-f
251                         We expect the method will provide a useful tool for the molecular study of co
252 le of Runx factors in leukemias, this review will provide an overview of the normal regulation and fu
253 viruses evade or exploit macrophage function will provide greater insight into viral pathogenicity an
254 y of ancient plant populations and, in time, will provide higher taxonomic resolution and more precis
255 ncology or imaging guideline recommendations will provide increased value or cause increased distress
256              Further expansion of this study will provide more insight into the long-term safety and
257 rstanding age-related changes to the UPR(ER) will provide new avenues for therapeutic intervention in
258 lating plasma proteins (the plasma proteome) will provide opportunities for unbiased discovery of nov
259                                  This review will provide readers with an updated vision of current a
260 erventions are being tested, which hopefully will provide translational insights to stop the growing
261                                  Future work will reassess these estimates in light of more clinical
262  those with HER2 and ER negative tumors, who will receive one of the widely-accepted chemotherapy reg
263 t's wishes; the family is too distressed and will regret the decision; overruling harms other patient
264 munity assemblages in future climates, which will require a mechanistic understanding of the trade-of
265              Elucidating cerebellar function will require an understanding of the interactions, both
266 des, extending those made in recent decades, will require continued research into mechanisms underlyi
267  alternative programs, comparison of results will require general agreement on definitions of respons
268 ultimate success of immunotherapy in the CNS will require improved imaging technologies and methods f
269                                 This process will require new skills and education in systems science
270 ration of the brain's vast synaptic networks will require new tools for high-throughput structural an
271                               These findings will require rethinking of how this class of endosomal p
272 agnosis and treatment for all people with TB will require simpler, more sensitive diagnostics and bro
273 preservation of average post-transplant eGFR will require sustained improvement in immunosuppression
274 (ART) to eliminate pediatric HIV-1 infection will require the characterization of maternal immune res
275 gh-density, low-power neuromorphic computing will require very large numbers of nanoscale nonlinear o
276 ormation for use in predicting how a patient will respond to a given proposed drug or treatment.
277  key to understanding how animal populations will respond to changing climatic conditions.
278 efit from fire, it is unknown how ecosystems will respond to increased burning and warming.
279                        Delays in dosing time will result in transient periods of lower concentrations
280 nsformation over time along these dimensions will reveal how the nature of language reflects human mi
281                                These studies will serve as a starting point to explore the nonlinear
282 peutics to clear persistently infected cells will soon allow measurable clinical advances toward an H
283               We anticipate that our results will spark renewed investigation in modulating the funct
284 e that this conceptual mechanistic framework will stimulate fruitful research that aims at unraveling
285           Our models predict that cell shape will strongly influence the fate of a cell lineage: we d
286                                  This review will summarize recent advances in dissecting the relativ
287 tion by testing whether a preconditioned cue will support conditioned reinforcement in rats.
288 ding population immunity to transmission and will sustain transmission as long as they do not attain
289 ned from minute patient-derived samples, and will therefore potentially allow the identification of c
290 epresents around 4% of the final product, it will therefore strongly influence the elemental and isot
291 icted the duration of time that viewers were willing to commit to narrative videos.
292 ggesting that one-third of patients might be willing to donate at imminent death, we estimate that be
293 of Wisconsin would be medically eligible and willing to donate each year at the time of imminent deat
294 sis, and offers hope that similar approaches will transform the management of patients with other pro
295 te a more accurate arrival-time picking that will ultimately improve the localization accuracy.
296 approaches are tackling these challenges and will ultimately serve as an engine for biological discov
297 owledge of these viral proteins improves, we will undoubtedly uncover how the multifunctional nature
298                         The optimal decision will vary in different social-ecological contexts, but s
299  close kin and that this gap in availability will widen in the coming decades.
300 e the nonlinear dynamics of atrial cells and will yield insights into the trigger and maintenance of

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