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1 is fundamental to management and conservation efforts, and will be necessary to ensure future plans and adaptation strat
3 n of numerous unbiased genome-wide and proteomic approaches will be necessary to fully understand the neuroepigenome and
4 hildren in conflict-affected and security-compromised areas will be necessary to prevent reintroduction of WPV into other
6 Further, such comprehensive energetic characterization will be necessary to benchmark the algorithms required to rat
7 prioritisation and innovative solutions to the blood crisis will be necessary to improve this situation and will require
8 h improvements in pulse parameters and X-ray area detectors will be necessary to unlock this potential.
9 Going forward, well-defined policy direction will be necessary to institutionalize ecosystem services appr
10 dditional research into the pathophysiology of this disease will be necessary to develop newer, more targeted therapeutic
11 nough for malaria elimination but rather additional efforts will be necessary to control the disease.
12 n of, such devastating surface reactions on both electrodes will be necessary to help realize the potential of high-capac
13 Understanding of these fundamental molecular events will be necessary to identify novel host targets, such as FAK
14 Trial continuation and additional randomised evidence will be necessary to establish the supposed superior efficacy
16 Prospective clinical trials with c-Met inhibitors will be necessary to validate MET exon 14 mutations as an imp
18 hophysiological processes contribute to the disease, and it will be necessary to understand this heterogeneity to find ef
19 progress from the laboratory to commercial applications, it will be necessary to develop industrially scalable methods to
22 ploit the potential of CAM crops and CAM bioengineering, it will be necessary to elucidate the evolution, genomic feature
23 To fully understand behavioral evolution, it will be necessary to identify the genetic mechanisms that med
24 rove the efficacy of microelectronic retinal prosthetics it will be necessary to better understand the response of retina
25 To identify HSCs from in vitro sources, it will be necessary to refine markers of HSCs matured ex vivo.
27 ablers of sustainable financing, governance, and leadership will be necessary to achieve access while preventing excess a
28 ith stereopsis, visual field expansion, and quality of life will be necessary to fully evaluate the role that improved Bi
29 Further validation in cell culture and mouse models will be necessary to establish causality for these genes.
30 further development, including incorporation of ontologies, will be necessary to improve the performance of the extractio
31 ht-energy harvesting, CO2 fixation, and carbon partitioning will be necessary to make major headway toward improving phot
32 r complications although elucidation of downstream pathways will be necessary to identify targets that do not promote nep
33 y propagated species, optimization of aquaculture practices will be necessary to maximize food production and minimize ec
34 nd allow immune recognition and clearance of this reservoir will be necessary to eradicate HIV-1 in infected individuals.
35 t of hypoxia, further nutrient reductions in the Baltic Sea will be necessary to reduce the ecosystems impacts of deoxyge
36 a population isolate like Finland, and larger sample sizes will be necessary to detect risk variants.
37 ments and increased efforts from industry and civil society will be necessary to break these vicious cycles.
39 normalize pH and carbon dioxide levels, but further studies will be necessary to demonstrate benefit with this technology
44 ral basis for how the brain tells time and operates in time will be necessary to develop general models of cognition.
45 roperties, but also their surrounding surface topographies, will be necessary to improve the yield of single quantum dot
47 patient population, and further adaptation of the treatment will be necessary to address the unmet needs of patients with
48 Furthermore, targeting specific cell types will be necessary to understand how regeneration of the diver
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