ライフサイエンスコーパス: window of opportunity

1 d if the CCR5 peptide is absent during their window of opportunity.

2 in the youngest patient implies a potential window of opportunity.

3 that interact within specific developmental windows of opportunity.

4 pies during this diagnostic and therapeutic "window of opportunity."

5 suggest that antiretroviral treatment in the window of opportunity after exposure to HIV could preven

6 ntial therapeutic value within a therapeutic window of opportunity after SEB encounter.

7 t application of biologic therapy within the window of opportunity and aid in the monitoring of respo

8 l, learning lessons from experience, seizing windows of opportunity, and ensuring sensitivity to cont

9 nfection period, however, presents a unique "window of opportunity," because there are a limited numb

10 NSCC who received erlotinib monotherapy in a window-of-opportunity clinical trial (patients scheduled

11 the knowledge base to be acquired before the window of opportunity closes for feasible management.

12 g evidence that communities can seize on the window of opportunity created by climate-induced shocks

13 -1 transmission could potentially narrow the window of opportunity during which a vaccine is able to

14 during infection defined an extremely narrow window of opportunity during which anti-TNF therapeutics

15 malaria parasite, the merozoite, has a small window of opportunity during which it must successfully

16 n multiple sclerosis lesions may determine a window of opportunity during which oligodendrocyte precu

17 ue that adolescence represents an additional window of opportunity during which substantial life cycl

18 e is appealing, because it might allow for a window of opportunity during which treatment regimens ca

19 in determining the critical periods (i.e., a window of opportunity) during perimenopause for restorin

20 nitiate antirheumatic therapy, a therapeutic window of opportunity early in the course of RA associat

21 ity of information to address whether such a window of opportunity exists for progesterone and its re

22 n of pancreatic cancer suggests that a large window of opportunity exists for the early detection of

23 y, we sought to identify whether a temporal "window of opportunity" exists during which cells of the

24 ce or repress exon 3 occurs during a limited window of opportunity following transcription, indicatin

25 ur in vitro and in vivo data not only open a window of opportunities for the development of novel can

26 The window of opportunity for a HIV-1 vaccine is from the ti

27 ve yet to be done, but it is likely that the window of opportunity for altering the course of brain d

28 These data imply a window of opportunity for anti-K-ras therapies after tum

29 This provides a window of opportunity for athletes to exploit with relat

30 ltured Rosa cells RG-II domains have a brief window of opportunity for boron-bridging intraprotoplasm

31 e prostasin, resulting in an extremely brief window of opportunity for both active matriptase and act

32 over a period of 10 to 15 years, providing a window of opportunity for chemoprevention and early inte

33 ement characteristics: The gate opens a time-window of opportunity for competence transitions during

34 ects of ZIKV can be reduced using a seasonal window of opportunity for conception that may minimize m

35 vasculature, reducing hypoxia and creating a window of opportunity for concurrent chemotherapy; thus,

36 Our findings highlight the rapidly closing window of opportunity for controlling the outbreak and a

37 This prolonged course of disease provides a window of opportunity for diagnosis before symptoms occu

38 c cancer progression and define a broad time window of opportunity for early detection to prevent dea

39 ganglion cell loss alone, it also suggests a window of opportunity for effective neuroprotection.

40 he TDP may represent an as yet unappreciated window of opportunity for extracellular cues to influenc

41 ts, where early vernal species have a narrow window of opportunity for growth before late spring spec

42 These results suggest that the window of opportunity for human DNA ligase I may extend

43 A window of opportunity for immune responses to extinguish

44 function in ACHM with age suggests that the window of opportunity for intervention by gene therapy i

45 r HIV-exposed infants, but there is a narrow window of opportunity for intervention.

46 sed attention on the period -9 to 24 mo as a window of opportunity for interventions against stunting

47 easures during early childhood, suggesting a window of opportunity for interventions targeting these

48 We show that the window of opportunity for invasion of drug resistant str

49 of hypomethylation (e.g. in tumor cells), a window of opportunity for L1 derepression arises, and ad

50 progression, and suggest that a substantial window of opportunity for locus coeruleus/ norepinephrin

51 scillation upstates are thought to provide a window of opportunity for memory consolidation, particul

52 Because of the limited window of opportunity for mtDNA transfer to the germline

53 f allergen-specific IgE, which can provide a window of opportunity for novel therapeutic intervention

54 To estimate the window of opportunity for ovarian cancer screening, we d

55 Early and accurate diagnosis offers a window of opportunity for parental counseling and manage

56 gene-encoded determinants that minimize the window of opportunity for PFI to bind provide a growth a

57 ate formation of free radicals may provide a window of opportunity for pharmacological rescue immedia

58 s and G1 phase is crucial for establishing a window of opportunity for pluripotency exit and the init

59 They also imply that there is a window of opportunity for prevention of AHT, and potenti

60 overall a relatively early phase, there is a window of opportunity for prevention that should not be

61 period appears to provide us with a crucial window of opportunity for prevention.

62 dilated cardiomyopathy in DMD and identify a window of opportunity for preventive interventions.

63 As a result, the window of opportunity for realizing the benefits of a bi

64 le pausing of polymerase provides a temporal window of opportunity for recruitment of factors to modu

65 m pregnancy to 24 months of age is a crucial window of opportunity for reducing undernutrition and it

66 ns the promoter of bound RepA and provides a window of opportunity for repA transcription.

67 This diversity provides a window of opportunity for research on genes and gene-env

68 ehabilitation while not missing the critical window of opportunity for successful transplantation whe

69 usion and metabolism mismatch may open a new window of opportunity for surgical intervention.

70 ure chop accumulation and thereby provides a window of opportunity for the cell to re-establish homeo

71 icular subpopulation apparently represents a window of opportunity for the initiation of potentially

72 We here identify a precise window of opportunity for the treatment of complex spina

73 woody vegetation due to drought may create a window of opportunity for these invaders.

74 ur results could point to a limited temporal window of opportunity for this therapeutic intervention.

75 election criteria are underway to expand the window of opportunity for thrombolysis.

76 potentially at preclinical stages, offers a window of opportunity for tolerogenic therapy.

77 Delayed treatment protocols may extend the window of opportunity for treatment of spinal cord injur

78 A window of opportunity for treatment was detected because

79 delayed in several countries, pointing to a window of opportunity for vaccination in a future pandem

80 demonstrate that by utilizing rapamycin, the window of opportunity for veto-based induction of tolera

81 ue in the mouse intoxication models revealed windows of opportunity for antibody therapeutic treatmen

82 Research has elucidated two distinct windows of opportunity for clinical use of hypothermia.

83 The findings indicate that the windows of opportunity for enhancing growth after spinal

84 y model in which core promoters define broad windows of opportunity for expression, by defining a ran

85 ritorial conflicts thus provide intermittent windows of opportunity for host reproduction.

86 Research aims to define the temporal windows of opportunity for interventions, test the safet

87 sions into an extended open state may create windows of opportunity for protein factors involved in D

88 ld be particularly beneficial when temporary windows of opportunity for safe access can be granted in

89 driven excitability changes provide temporal windows of opportunity for single pyramidal cells to sup

90 rely on alternating waves of inhibition and windows of opportunity for spiking.

91 ulation of anti-TNF therapy identified clear windows of opportunity for this intervention as well as

92 ring medical attention thus represent unique windows of opportunity for trafficked persons to receive

93 cuss the emerging therapies, and examine the windows of opportunity for treating AKI.

94 nds and that fast elongation compresses the "window of opportunity" for recognition of upstream splic

95 This delay provides a critical "window of opportunity" for recruitment of lineage-specif

96 The totality of data indicates that the "window of opportunity" for reducing coronary heart disea

97 To understand if these processes act as "windows of opportunity" for changes in cell identity, we

98 This suggests the existence of temporal "windows of opportunity" for tumours of different types i

99 also indicated that there was a therapeutic window of opportunity from P4 through P8 defined by the

100 While such a window of opportunity has been described for estrogen, t

101 A window of opportunity has been suggested for reducing th

102 unctional neurosurgical techniques, a unique window of opportunity has recently arisen to target pote

103 A 'critical window of opportunity' has been proposed for the efficac

104 We explored the window of opportunity hypothesis in relation to cognitiv

105 ent conflicting data can be explained by the window of opportunity hypothesis suggesting that the neu

106 Moreover, they lend credence to the "window of opportunity" hypothesis during which hormone r

107 This has led to the 'Window of Opportunity' hypothesis, which states that est

108 Arapaima management is a superb window of opportunity in harmonizing the co-delivery of

109 ur results support the concept of a critical window of opportunity in sepsis resuscitation.

110 ould be evaluated as adjuncts to broaden the window of opportunity in the treatment of the reperfusio

111 prediagnostic phase of the disease offers a window of opportunity in which disease-modifying therapi

112 Instead, there may be a tumor stage-specific window-of-opportunity in which conserving STMN1 expressi

113 d (ii) that climate-related shocks can offer windows of opportunity in which latent local adaptive ca

114 There are windows of opportunity in which vaccination would be ben

115 with its control by vaccination offering a "window of opportunity" in which infection may occur.

116 and mutational processes that can determine "windows of opportunity" in time to detect rapidly progre

117 This short window of opportunity is applicable to HIV infections an

118 in this activity, suggesting that a temporal window of opportunity is missed after zen knockdown.

119 ble but requires early consideration, as the window of opportunity may be short.

120 Using these values, our model predicts a window of opportunity of 2.9 years, indicating that one

121 on of ictus patients, offering a therapeutic window of opportunity of great interest for patient reco

122 rt longitudinal studies helping to untangle 'windows of opportunity' or reverse causation with vascul

123 reserved into adult life such that a lengthy window of opportunity should exist for intervention with

124 tinct recruitment mechanisms, this creates a window of opportunity that could be exploited for the de

125 STATEMENT Critical periods are developmental windows of opportunity that ensure the proper wiring of

126 These findings may be reminiscent of the "Window of Opportunity" theory, which suggests that estro

127 rentiate enantiomers by DECS opens up a vast window of opportunity to characterize the class effects

128 onset renal cystic disease, which provides a window of opportunity to conduct unilateral nephrectomy

129 hich raises the question of what is the real window of opportunity to detect high-grade serous perito

130 during periods of organ failure to permit a window of opportunity to diagnose and treat underlying d

131 There is a window of opportunity to dilute the legacy of historical

132 of viral Ag thus affords persisting virus a window of opportunity to escape from immune surveillance

133 rmath of mass shootings is often viewed as a window of opportunity to garner support for gun control

134 in response to immunotherapy also presents a window of opportunity to illuminate mechanisms of resist

135 The preschool years offer a unique window of opportunity to instill healthy life-style beha

136 experimental evidence reveals only a narrow window of opportunity to invade the mesenchyme of the me

137 linical treatments, eventually expanding the window of opportunity to optimally enhance cognition and

138 nce represents a potentially underrecognized window of opportunity to optimize bone mass.

139 nd the possibility of a prodrome indicates a window of opportunity to potentially reverse early disea

140 degenerative retinal disease, there may be a window of opportunity to preserve daylight vision, as th

141 The data further suggest a short window of opportunity to prevent the loss of CD4(+) T ce

142 gan failures, thus providing patients with a window of opportunity to recover from potentially life-e

143 This suggests a window of opportunity to repair ischemic MR after which

144 te the adaptive role of reconsolidation as a window of opportunity to rewrite emotional memories, and

145 Findings open a novel window of opportunity to study alteration of GABAA-/GABA

146 di is a small town in Brazil that provides a window of opportunity to study the influence of sleep pa

147 emerging class of regulatory RNA and offer a window of opportunity to target epigenetic modifications

148 term graft outcome but importantly provide a window of opportunity to therapeutically intervene to pr

149 tion of rapamycin significantly extended the window of opportunity to veto based deletion by preventi

150 sts of activity during REM sleep may provide windows of opportunity to synchronize the hippocampal tr

151 The window of opportunity was tested by delaying angiotensin

152 education of the immune system during this "window of opportunity," when microbial colonization has