ライフサイエンスコーパス: winged helix

1 is subfamily include a divergent DNA-binding winged helix, a leucine zipper, a zinc finger, and a pol

2 In comparison, weaker interaction of FOXA1 winged helix, and the NH(2)-terminal domains was documen

3 d-forming N-terminal domain, which reveals a winged-helix architecture, with additional structural el

4 itself to one Cul3 molecule and binds to the winged-helix B domain at the C terminus of the second Cu

5 ic residue predicted to be at the tip of the winged helix beta-hairpin), showed a decrease in DNA bin

6 that recognize divergent DNA sequences via a winged helix binding motif.

7 are critical for the development of forkhead-winged helix box transcription factor 3(+) regulatory T

8 he chicken homolog of FoxD3, a member of the winged-helix class of transcription factors, and analyze

9 FoxA, the paradigm pioneer TF, has a winged helix DBD that resembles linker histone and there

10 e that deleted the Foxm1b exons encoding the winged helix DNA binding and transcriptional activation

11 AphA is a dimer with an N-terminal winged helix DNA binding domain that is architecturally

12 -mediated phosphorylation of a serine in the winged helix DNA binding motif curtails FoxO1 nucleosome

13 family of TFs, defined by a highly conserved winged helix DNA-binding domain (DBD), has diverged into

14 cription factors that shares homology in the winged helix DNA-binding domain and the members of which

15 cription factors that shares homology in the winged helix DNA-binding domain and whose members play e

16 U_0916 protein identified two domains, one a winged helix DNA-binding domain common for transcription

17 The region C-terminal to its winged helix DNA-binding domain is required for transfor

18 The 95 amino acid residue protein contains a winged helix DNA-binding domain with an extended C-termi

19 tion of mouse HOP2, which contains a typical winged helix DNA-binding domain.

20 iative (www.mcsg.anl.gov), revealed the same winged helix DNA-binding motif that was recently found i

21 monomeric subunits are predicted to adopt a winged helix DNA-binding motif which dimerizes through f

22 AphA is a winged helix DNA-binding protein that enhances the abili

23 scriptional regulators comprises a subset of winged helix DNA-binding proteins and includes numerous

24 third of the polypeptide, just distal to its winged-helix DNA binding domain.

25 required the HNF-6 Cut-Homeodomain and FoxA2 winged-helix DNA binding domains.

26 (Fox) proteins share the Forkhead domain, a winged-helix DNA binding module, which is conserved amon

27 Xis is a winged-helix DNA binding protein that cooperatively bind

28 tional regulators belonging to the family of winged-helix DNA binding proteins known as the Fox famil

29 mologous to the SlyA and MarR subfamilies of winged-helix DNA binding proteins.

30 mpletely different manner from the canonical winged-helix DNA recognition motif.

31 monomer comprises two domains: an N-terminal winged-helix DNA-binding domain and a C-terminal PLP-bin

32 llular activities (AAA+-class ATPase) with a winged-helix DNA-binding domain.

33 hich are located within wings 1 and 2 of its winged-helix DNA-binding domain.

34 Two typical winged-helix DNA-binding domains are connected by a well

35 of Sso10a and show that it is a homodimer of winged-helix DNA-binding domains.

36 crystal structure of Vfr shows that it is a winged-helix DNA-binding protein like its homologue cycl

37 homologous to the winged helix-turn-helix ('winged helix') DNA-binding/transcription activation doma

38 y unrecognized domains in ASXL1: a forkhead (winged-helix) DNA-binding domain and a deubiquitinase ad

39 We show that Cac1C forms a winged helix domain (WHD) and binds DNA in a sequence-in

40 C-terminus of Cac1, including the structured winged helix domain and glutamate/aspartate-rich domain,

41 uch a region consists of a zinc domain and a winged helix domain and plays an important role in enzym

42 unds binding to a protein pocket between the winged helix domain and topoisomerase-primase domain, re

43 In this structural model, a single winged helix domain binds to both DNA and other proteins

44 tsK interacts with KOPS through a C-terminal winged helix domain gamma.

45 binding to a H3-H4 dimer activates the Cac1 winged helix domain interaction with DNA.

46 Moreover, an intact Cdc6 winged helix domain is required for efficient inhibition

47 NA in a manner similar to RecQ1, whereas the winged helix domain may assume alternative conformations

48 erminal domain near Pol I wall or the tandem winged helix domain of A49 at a partially overlapping lo

49 of these complexes were mapped to the second winged helix domain of human ESCRT-II subunit VPS25 and

50 mino-acid stretch directly C-terminal of the winged helix domain of Qin.

51 merization domain on the Pol II lobe and the winged helix domain of the TFIIF small subunit Tfg2 abov

52 ding is mediated principally by a C-terminal winged helix domain that inserts deeply into the major a

53 Qin (amino acids 246-451, extending from the winged helix domain to the C-terminus) and identified am

54 re defective, disrupts the fork headrelated, winged helix domain-containing protein Foxi1.

55 and that the interaction is mediated by the winged helix domain.

56 an N-terminal AAA(+) domain and a C-terminal winged-helix domain (WHD), but use remarkably few base-s

57 This region folds into a winged-helix domain and an extended coiled-coil domain t

58 r on the proposed recognition surface of the winged-helix domain and around the PRPP binding site at

59 in a novel combination with the DNA-binding winged-helix domain as a repressor of purine genes.

60 cQ has evolved an SSB-Ct binding site on its winged-helix domain as an adaptation that aids its cellu

61 The winged-helix domain at the C terminus of Cdc6 interacts

62 The winged-helix domain contains putative DNA-binding residu

63 s indicate that ORC encircles DNA, using its winged-helix domain face to engage the mini-chromosome m

64 in the RecQ variants indicate a role for the winged-helix domain in helicase activity beyond SSB prot

65 A positively charged surface on the winged-helix domain likely binds specific DNA sequences

66 rates that the helix-turn-helix motif in the winged-helix domain mediates the interaction with this s

67 Here, we report a cocrystal structure of the winged-helix domain of human RNA polymerase II-associati

68 th tubulin monomers via the carboxy-terminal winged-helix domain of Ska1, providing the structural ba

69 Each mutation affects the forkhead/winged-helix domain of the scurfin protein, indicating t

70 A-dependent conformational rearrangements: a winged-helix domain pivots approximately 90 degrees to c

71 Soluble forms of the cytoplasmic winged-helix domain regulated ompU and ompT gene express

72 for membrane localization of ToxR is for its winged-helix domain to co-operate with TcpP to activate

73 alpha/beta fold, a short helical motif and a winged-helix domain, resulting in the burial of the casp

74 s, a RecQ-specific zinc-binding domain and a winged-helix domain, the latter implicated in DNA strand

75 between RecQ and SSB is mediated by the RecQ winged-helix domain, which binds the nine C-terminal-mos

76 nct from the previously described C-terminal winged-helix domain.

77 ng site has been identified within the RAP74 winged-helix domain.

78 to the NTR and to the N-terminal half of the winged-helix domain.

79 nnovation that involve founder 'p-loop' and 'winged helix' domain structures.

80 The winged helix domains are at opposite ends of the extende

81 ithin the ATPase, Topoisomerase/Primase, and Winged helix domains, including four that encode protein

82 AAA+-like domains forming one layer, and the winged-helix domains (WHDs) forming a top layer.

83 CHMP7's N terminus comprises tandem Winged-Helix domains [6], and, by using homology modelin

84 SelB-C consists of four similar winged-helix domains arranged into the shape of an L.

85 n factors (HNF-3gamma and RFX1) and from the winged-helix domains found within the RAP30 subunit of T

86 wo-layered notched ring in which a collar of winged-helix domains from the Orc1-5 subunits sits atop

87 stallography, we show that Cdt1 contains two winged-helix domains in the C-terminal half of the prote

88 This is the first example of winged-helix domains involved in RNA binding.

89 th the N-terminal OB fold and the C-terminal winged-helix domains of Stn1 can bind to the Pol12 subun

90 The wings and helices of the winged-helix domains remain exposed on the surface of th

91 We recently demonstrated that the winged helix factor forkhead box protein A3 (Foxa3) regu

92 es and show here for the first time that the winged helix factor Foxa3 promotes adipocyte differentia

93 e result of increase binding of the forkhead winged helix factor FoxD1 to a TGF-beta-responsive eleme

94 l lines of evidence suggest that the related winged-helix factor Pintallavis functions as the ortholo

95 The winged helix factors Foxa1 and Foxa2 are essential membe

96 ck transcription factor (HSF) belongs to the winged helix family of proteins.

97 Foxa1 is a member of the winged helix family of transcription factors and is expr

98 data suggested that a member of the Forkhead/winged helix family of transcription factors mediated th

99 hat the Foxk1 gene, a member of the forkhead/winged helix family of transcription factors, is express

100 nd indicate that AphA is a new member of the winged helix family of transcription factors.

101 The oncoprotein Qin is a member of the winged helix family of transcriptional regulators.

102 Although the forkhead/winged-helix family member FOXP3 is critical for Treg di

103 maller N-terminal domain that belongs to the winged-helix family of DNA binding proteins.

104 FOXO1A, a member of the forkhead winged-helix family of proteins is a transcription facto

105 Foxp3, a member of the forkhead/winged-helix family of transcription factors, acts as th

106 jI gene, which encodes a novel member of the winged-helix family of transcriptional regulators and al

107 nated Foxp3) is a new member of the forkhead/winged-helix family of transcriptional regulators and is

108 Foxp3, a winged-helix family transcription factor, serves as the

109 uld represent a new functional class of the "winged helix" family.

110 vitro, and reveals how subtle changes in the winged-helix fold can modulate the functional properties

111 Both structures show the "winged-helix" fold typical of GH1 and GH5 and are very s

112 ted domain-swapping interactions between the winged-helix folds and AAA+ modules of neighbouring prot

113 on factors, binds DNA via a highly conserved winged-helix "forkhead box" motif used by other regulato

114 Foxe3 encodes a winged helix-forkhead transcription factor that is initi

115 cis-element upstream of Tbx1 that recognized winged helix/forkhead box (Fox)-containing transcription

116 Deletion of the Foxa2 gene, encoding a winged helix/forkhead box transcription factor that is s

117 foxd3 encodes a winged helix/forkhead class transcription factor express

118 transcription factors share homology in the winged helix/forkhead DNA-binding domain and play import

119 Because HILS1 also belongs to the large winged helix/forkhead protein superfamily, HILS1 may als

120 We show here that the Foxn4 winged helix/forkhead transcription factor is coexpresse

121 Here, we show that the Foxn4 winged helix/forkhead transcription factor is expressed

122 a C2H2 zinc finger, a leucine zipper, and a winged-helix/forkhead (FKH) domain.

123 cription factors including the Fox family of winged-helix/forkhead DNA-binding proteins.

124 whether NKX2.1 interacts with members of the winged-helix/forkhead family of FOXA transcription facto

125 ntly identified members of the Fox family of winged-helix/forkhead transcription factor genes.

126 -function mutations in Whn (Hfh11, Foxn1), a winged-helix/forkhead transcription factor, cause the nu

127 ed by an unidentified member of the forkhead/winged helix (Fox) family of transcription factors.

128 The winged helix gene Brain factor-1 (BF1) has a pleiotropic

129 FOXC2 is a winged helix gene that has been shown to counteract obes

130 us aureus CzrA and cyanobacterial SmtB, are "winged" helix homodimeric DNA-binding proteins that bind

131 DPBD consists of a winged helix-like motif and an unstructured C-terminal r

132 The C-terminal, winged helix-loop-helix, protein-protein interaction dom

133 helix proteins via the versatile use of the winged helix motif as a homo- or heterodimerization scaf

134 m the IGFBP1 promoter via a highly conserved winged helix motif.

135 and that the C-terminal domain might have a winged helix motif.

136 Xis adopts an unusual "winged"-helix motif that is modeled to interact with the

137 Xis forms a unique winged-helix motif that interacts with the major and min

138 The IBD structures reveal a winged-helix motif with prokaryotic and eukaryotic featu

139 The DNA binding domain has a winged-helix motif, and the C-terminal domain resembles

140 uble wing' to emphasize similarities to the 'winged-helix' motif.

141 nucleic acid binding surfaces of the RRM and winged-helix motifs, although present in the RNA binding

142 he others form unexpected Zn(2+)-binding and winged-helix motifs.

143 We map binding to the winged helix of H1 and determine that citrulline 53 repr

144 The winged-helix or forkhead class of transcription factors

145 involves the first FF motif of p190A and the winged helix/PCI domain of eIF3A, is enhanced by serum s

146 lpha1 and alpha3 in both subunits, a mode of winged helix protein dimerization that is reminiscent of

147 res of the DNA binding domain of a conserved winged helix protein HFH-1 and its DNA complexes.

148 e data suggest that the winged region of the winged helix protein participates in DNA binding and act

149 This, in turn, suggests that Cnr is also a winged helix protein, a possibility that is supported by

150 or the nuclear transcription factor Forkhead winged helix protein-3 and able to inhibit naive T cell

151 nd a concomitant down-regulation of Forkhead/winged-helix protein 3 (Foxp3), TGFbeta, and IL-10 expre

152 We propose that MarR also belongs to the winged-helix protein family and has a similar mode of DN

153 lear factor 3gamma (HNF-3gamma), making it a winged-helix protein.

154 om phage to man, the DNA-binding activity of winged helix proteins can be regulated by other winged h

155 The structural comparison of winged helix proteins HFH-1 and Genesis and their DNA co

156 ged helix proteins can be regulated by other winged helix proteins via the versatile use of the winge

157 scussed on the basis of comparisons to other winged helix proteins.

158 criptional regulator SarA protein family are winged-helix proteins that are involved in gene regulati

159 SarS, and MarR, we further classified these winged-helix proteins to three subfamilies, SarA, SarS,

160 otic homeodomain proteins and the "wings" of winged-helix proteins, but structurally distinct.

161 ain, and the C-terminal part, which includes winged-helix, ratchet, and oligonucleotide/oligosacchari

162 ution x-ray crystal structure of the dimeric winged helix SarA protein, which differs from the publis

163 The predicted Cdc6 domain III winged-helix structure may well be responsible for dimer

164 ologous regions of both proteins fold into a winged-helix structure, which specifically binds to the

165 whose structure is remarkably similar to the winged-helix structures of histones H1 and H5.

166 is and (lambda)Xis adopt related prokaryotic winged-helix structures.

167 action is direct and is mediated by the RecQ winged helix subdomain and the C terminus of SSB.

168 etween these repeats and the more C-terminal winged helix subdomain.

169 ors, namely Kite dimers (Kleisin interacting winged-helix tandem elements), interact with Smc-kleisin

170 Binding of the winged helix to the protrusion is PIC specific.

171 Each subunit has a winged helix topology with a unique structure among init

172 ro, as demonstrated by cytokine and forkhead/winged helix transcription factor (FoxP3) gene and prote

173 beta induce naive T cells to become forkhead/winged helix transcription factor (Foxp3) positive regul

174 of the T(reg) cell lineage factor, Forkhead/winged helix transcription factor (Foxp3), and tolerance

175 essage for the transcription factor forkhead/winged helix transcription factor (FOXP3).

176 Additionally, CD4+ forkhead/winged helix transcription factor 3+ T cells were also d

177 Foxc1 encodes a forkhead/winged helix transcription factor expressed in many embr

178 Foxl1 is a winged helix transcription factor expressed in the mesen

179 Two members of the forkhead/winged helix transcription factor family, Foxa1 and Foxa

180 e X-linked Foxp3 is a member of the forkhead/winged helix transcription factor family.

181 ted motility and is a putative member of the winged helix transcription factor family.

182 a 35,000-fold higher expression of forkhead/winged helix transcription factor forkhead box (FOXF1) n

183 ed genome-wide binding sites of the forkhead/winged helix transcription factor Foxa1, which functions

184 l YAC-based Foxa3Cre transgene to delete the winged helix transcription factor Foxa2 (formerly HNF-3b

185 tro analysis has suggested that the forkhead/winged helix transcription factor Foxa2 (formerly HNF-3b

186 The variant histone H2A.Z and the winged helix transcription factor Foxa2 both act to regu

187 nd cell type-specific gene ablation that the winged helix transcription factor Foxa2 is required for

188 Expression of the forkhead/winged helix transcription factor FoxD1 (BF-2) is restri

189 The winged helix transcription factor Foxd1 (previously know

190 In this study, we show that the winged helix transcription factor Foxd3 is expressed in

191 We show in both mouse and zebrafish that the winged helix transcription factor Foxg1 is expressed in

192 The winged helix transcription factor Foxl1 is a marker for

193 The winged helix transcription factor Foxl1 localizes to mes

194 The winged helix transcription factor FoxO1 is a growth-atte

195 duction in the CD4(+)CD25(+)CD62L(+)forkhead/winged helix transcription factor gene (Foxp3(+)) compar

196 cell-specific transcription factor forkhead/winged helix transcription factor gene (FOXP3) in CD4+CD

197 tabolite NAD induce death in murine forkhead/winged helix transcription factor gene-expressing CD4+CD

198 ed mice possess increased levels of forkhead/winged helix transcription factor gene-expressing CD4+CD

199 generation of allospecific CD4CD25 forkhead/winged helix transcription factor P3 (FOXP3) T-regulator

200 L, however, significantly increased forkhead/winged helix transcription factor P3 (FOXP3) Tregs, wher

201 In this study we find that the winged helix transcription factor Rfx2 is expressed in m

202 Foxk1 is a forkhead/winged helix transcription factor that is restricted to

203 ances is restrained by CD4(+)CD25(+)forkhead/winged helix transcription factor(+) regulatory T cells.

204 hymic mice depleted of CD4(+)CD25(+)forkhead/winged helix transcription factor(+) regulatory T cells.

205 D25+ glucocorticoid-inducible TNFR+-Forkhead/winged helix transcription factor+ populations and effic

206 ported that expression of the human forkhead/winged helix transcription factor, CHES1 (checkpoint sup

207 Members of the Foxa family of forkhead/winged helix transcription factor, Foxa1 and Foxa2, have

208 The winged helix transcription factor, FOXA2, is expressed i

209 We identified a forkhead/winged helix transcription factor, Foxj3, which was expr

210 Recently, the forkhead/winged helix transcription factor, FoxP3, has been shown

211 opulation does acquire the X-linked forkhead/winged helix transcription factor, FoxP3, which is assoc

212 the salivary placodes by fork head (fkh), a winged helix transcription factor.

213 The winged helix transcription factors Foxa1 and Foxa2 are e

214 we demonstrate novel roles for the forkhead/winged helix transcription factors Foxa1 and Foxa2 in th

215 -beta and -gamma) constitute a sub-family of winged helix transcription factors with multiple roles i

216 2/Mfh1 genes encode closely related forkhead/winged helix transcription factors with overlapping expr

217 The winged helix transcription factors, hepatocyte nuclear f

218 member of the regulatory factor X family of winged helix transcription factors.

219 ires the organ specification factor PHA-4, a winged-helix transcription factor expressed in all phary

220 ES1; FOXN3) encodes a member of the forkhead/winged-helix transcription factor family.

221 onditional deletion of the gene encoding the winged-helix transcription factor Foxa2 (Forkhead box a2

222 over a dramatic and unpredicted role for the winged-helix transcription factor Foxa2 (formerly HNF-3

223 In this study, we elucidate the roles of the winged-helix transcription factor Foxa2 in ventral CNS d

224 teracts with and inhibits DNA binding by the winged-helix transcription factor FoxH1 (FAST), a critic

225 However, some DNA-BPs, such as the winged-helix transcription factor FOXO1, are difficult t

226 Forkhead winged-helix transcription factor Foxp3 serves as the de

227 The winged-helix transcription factor HNF3beta/FoxA2 is expr

228 FOXP1 (Forkhead box-P1) is a winged-helix transcription factor that is differentially

229 Foxg1, a winged-helix transcription factor, promotes the developm

230 of the foxd3 gene, which encodes a conserved winged-helix transcription factor.

231 , including fork head (fkh), which encodes a winged-helix transcription factor.

232 fespan extension requires DAF-16, a forkhead/winged-helix transcription factor.

233 differ significantly from those of bona fide winged-helix transcription factors (HNF-3gamma and RFX1)

234 Members in the superfamily of the forkhead/winged-helix transcription factors are known to play a c

235 We demonstrate here that the winged-helix transcription factors Foxa1 and Foxa2 co-oc

236 ist), a novel member of the Foxi-subclass of winged-helix transcription factors that is involved in t

237 RovA, a member of the MarR/SlyA family of winged-helix transcription factors, regulates expression

238 The forkhead/winged-helix transcription factors, XFast-1/XFoxH1a and

239 ell phenotypes, suppressor ability, forkhead winged/helix transcription factor box P3 (FOXP3) gene, a

240 Members of the MarR family of winged helix transcriptional regulators have been shown

241 family of prokaryotic metalloregulators are winged-helix transcriptional repressors that collectivel

242 Although the RepA and DnaD NTD both contain winged helix-turn-helices, the DnaD NTD self-assembles i

243 Its cytoplasmic domain is homologous to the winged helix-turn-helix ('winged helix') DNA-binding/tra

244 domains represent a growing subfamily of the winged helix-turn-helix (HTH) domain family whose member

245 ture consists of an intertwined dimer with a winged helix-turn-helix (HTH) motif.

246 n1 (Stn1C) was found to comprise two related winged helix-turn-helix (WH) motifs, one of which is mos

247 n factor complexes and contain an N terminal winged helix-turn-helix (wHTH) DNA binding domain (DBD).

248 form a dimer, with each monomer harboring a winged helix-turn-helix (WHTH) DNA-binding motif.

249 yclases, FhlA) domain that binds BCAAs and a winged helix-turn-helix (wHTH) domain that binds to DNA,

250 in ligase of Escherichia coli belongs to the winged helix-turn-helix (wHTH) family of transcriptional

251 TFs with winged helix-turn-helix (wHTH) motifs use an alpha helix

252 PF0610 is a novel winged helix-turn-helix (wHTH) protein with a rubredoxin

253 The La motif adopts a winged helix-turn-helix architecture that has a highly c

254 at least two receiver domains, an OmpR-class winged helix-turn-helix DNA binding domain, and a histid

255 To bind DNA, OhrR employs a chimeric winged helix-turn-helix DNA binding motif, which is comp

256 d binding site, partially overlapping with a winged helix-turn-helix DNA binding site.

257 -terminal regulatory domain and a C-terminal winged helix-turn-helix DNA-binding domain, with phospho

258 ding, while the N-terminal domains contain a winged helix-turn-helix DNA-binding motif and are arrang

259 is composed of three domains: an N-terminal winged helix-turn-helix domain (WH), a GAF-like domain,

260 R on a conserved arginine residue within the winged helix-turn-helix domain is necessary for modulati

261 al domain is fused to a C-terminal MarR-like winged helix-turn-helix domain that is expected to be in

262 family nucleases, are replaced by an unusual winged helix-turn-helix domain, where the "wing" is cont

263 e wing domain predicted by homology with the winged helix-turn-helix family of activators.

264 s overall fold resembles closely that of the winged helix-turn-helix family of DNA-binding proteins.

265 the 28 degrees rigid body rotations of each winged helix-turn-helix motif and DNA dissociation.

266 NrpR contained a putative N-terminal winged helix-turn-helix motif followed by two mutually h

267 (chxR), whose amino acid sequence contains a winged helix-turn-helix motif similar to the DNA-binding

268 e N-terminal DNA-binding domain contains the winged helix-turn-helix motif, and the C-terminal presum

269 the carboxyl-terminal domain binds DNA via a winged helix-turn-helix motif.

270 t with the DNA in the classical fashion of a winged helix-turn-helix motif.

271 Z adopts a unique fold in which three tandem winged helix-turn-helix motifs scaffold a positively cha

272 onal changes needed to allow the DNA-binding winged helix-turn-helix motifs to interact with the cons

273 ative orientation of the two DNA-interacting winged helix-turn-helix motifs.

274 ected residues map to the wing domain of the winged helix-turn-helix of ToxR.

275 tion crystal structure of apo-MtaN reveals a winged helix-turn-helix protein with a protruding 8-turn

276 The FadR-DNA complex reveals a novel winged helix-turn-helix protein-DNA interaction, involvi

277 Unlike other winged helix-turn-helix proteins, HSF's wing does not ap

278 in the modes of DNA binding is evident with winged helix-turn-helix proteins, raising doubts that me

279 eet is a unique feature of the OmpR group of winged helix-turn-helix proteins.

280 of the yeast transcription factor Mbp1 is a winged helix-turn-helix structure, with an extended DNA

281 PhoPC exhibits a typical fold of the winged helix-turn-helix subfamily of response regulators

282 posed of an N-terminal DNA binding domain of winged helix-turn-helix topology and a C-terminal dimeri

283 e riboflavin kinase domain and a DNA-binding winged helix-turn-helix-like domain.

284 ovel 7 kDa T7 protein, Gp5.7, which adopts a winged helix-turn-helix-like structure and specifically

285 ix hydrolase-like domain and the DNA-binding winged-helix-turn-helix (wHTH) domain.

286 The structure reveals the presence of a winged-helix-turn-helix DNA binding motif, but the locat

287 AbiEi has an N-terminal winged-helix-turn-helix domain that is required for repr

288 domain and a C-terminal circularly permuted winged-helix-turn-helix domain.

289 tudies show that RacA contains an N-terminal winged-helix-turn-helix module connected by a disordered

290 RctB contains at least three DNA binding winged-helix-turn-helix motifs, and mutations within any

291 OmpR is a winged helix-turnhelix DNA-binding protein that function

292 The initiator belongs to the family of winged helix type of proteins.

293 Membrane localization of the winged helix was sufficient for both omp gene regulation

294 We have localized the position of the TFE winged helix (WH) and Zinc ribbon (ZR) domains on the RN

295 FIIE-like factors, which is characterised by winged helix (WH) domain expansion in eukaryotes and los

296 we identify and determine the structure of a winged helix (WH) domain from human MUS81, which binds D

297 e present a model for the interaction of the winged helix (WH) domain of ORC2 with DNA that differs f

298 The C-terminal winged helix (WH) domains of Tfg1 and Tfg2 are mobile, b

299 Deleting or mutating K99 of the N-terminal winged helix (WH) motif in ASH2L abrogates H2Bub-depende

300 Helicase activity, as well as the conserved winged-helix (WH) motif and the helicase and RNase D C-t