ライフサイエンスコーパス: wise

1 ors in mice with mutations of Wnt inhibitor, Wise.

2 Wnt/beta-catenin signaling independently of Wise.

3 doubt, referral to such a centre is probably wise.

4 ter rearrangements are coupled with the step-wise 30S-subunit 'closure', providing insights into the

5 partial saturation protocol providing voxel-wise absolute quantification of GABAA receptor concentra

6 then Sox2, and finally Oct4, alongside step-wise activation of ExEn genes.

7 showing significant associations after gene-wise adjustment for multiple comparisons (p < .0026).

8 where the local elastic properties vary step-wise along the length of the material.

9 tration of the estimation of the InSAR pixel-wise ALTs.

10 Whole-brain vertex-wise analyses identified three clusters in prefrontal co

11 and default-mode) were extracted, and voxel-wise analyses of covariance were conducted to compare th

12 Vertex-wise analyses revealed significant thinning of over 85%

13 In conclusion, our voxel-wise analysis indicates that deteriorating erectile func

14 Voxel-wise analysis of anatomical magnetic resonance imaging d

15 a novel correlation-based algorithm by step-wise analysis of gene expression data in 558 blood sampl

16 h those obtained via traditional timepoint-: wise analysis shows that time-course analysis together w

17 Detailed voxel-wise analysis was performed on data from a prospective c

18 create high-coverage libraries of 1,521 two-wise and 51,770 three-wise barcoded combinations of 39 h

19 Lrp4 mediates the Wnt inhibitory function of Wise and also modulates Wnt/beta-catenin signaling indep

20 rectly with a wide range of arenes in a step-wise and controlled manner.

21 regression method that can detect both group-wise and individual associations between SNPs and expres

22 Two approaches, pixel-wise and object-wise, were investigated to group kernels

23 Whole-brain voxel-wise and parametric modulator analyses examined early an

24 a FBXO33 role in ADHD was found through gene-wise and pathway enrichment analyses in our genomic stud

25 n the bipolar and control groups using voxel-wise and regional analyses.

26 ing three methods: (i) mean-field, (ii) pair-wise, and (iii) one-hole approximations.

27 We propose a step-wise approach to the management of pulmonary disease in

28 A step-wise approach, including comparing three stains, was use

29 The pair-wise approximation performs better in the transient regi

30 The mean-field and pair-wise approximations give indistinguishable asymptotic re

31 results provide further evidence for a step-wise assembly of IAV structural components, regulated by

32 ular switch coupled to the high-affinity end-wise association of FtsZ monomers.

33 In addition, we demonstrate that pair-wise associations between miRNAs can be used to group th

34 oduce a new approach to identify novel group-wise associations between sets of SNPs and sets of genes

35 strates that decoupling individual and group-wise associations for association mapping is able to imp

36 Considering group-wise associations significantly improves the accuracy of

37 tomatically infer the proper number of group-wise associations.

38 accuracy, and inferring individual and group-wise associations.

39 andardized reference on how to conduct voxel-wise asymmetry analyses is missing.

40 libraries of 1,521 two-wise and 51,770 three-wise barcoded combinations of 39 human microRNA (miRNA)

41 ptake was compared between groups on a voxel-wise basis and in regions of interest.

42 uter cleft, providing perfect sites for step-wise binding of two anions within a single cavity.

43 re complex set of dynamics, and are not step-wise but interdependent and continuous.

44 ovascular or noncardiovascular by a panel of WISE cardiologists masked to angiographic data.

45 elative histopathologic data yielded a voxel-wise CBS that outperformed single quantitative MR imagin

46 temporal positioning of individual and group-wise cell activity.

47 esults with acclimation of PhiPSII to a step-wise change in irradiance where the growth irradiance wa

48 to evaluate decisions for trade-offs to make wise choices.

49 ies enable a genome-wide measurement of pair-wise chromatin interaction.

50 Genome-wide analysis of pair-wise chromatin interactions using chromatin conformation

51 Here we present ChromDiff, a group-wise chromatin state comparison method that generates an

52 ients and comparison subjects by subdivision-wise classical morphometric analysis.

53 The pixel-wise classification assigned a class to every pixel from

54 Object-wise classification was performed using two methods for

55 in by using an analysis of covariance family-wise cluster corrected for multiple comparisons, with a

56 Regarding microbiome sample-wise clustering, we also show that the rarefying procedu

57 Failures in step-wise cohesin removal result in aneuploid gametes, preven

58 d DNA template and generate millions of pair-wise combinations.

59 and ENCODE projects, we provide novel group-wise comparative analyses across sex, tissue type, state

60 A gene-wise comparative analysis shows that deep learning achie

61 bgroups with different risks of PCSM in pair-wise comparison (p < 0.0001).

62 s showed a median distance of 0.603 for pair-wise comparison of fragments indicating significant hete

63 Post-hoc pair-wise comparison revealed increased frontocentral slow be

64 By both volumes of interest and voxel-wise comparison, 18-kDa translocator protein-binding was

65 In pair-wise comparisons of anti-tumor necrosis factor agents, i

66 nsula (P < 0.05 corrected for multiple voxel-wise comparisons within the prespecified anatomical regi

67 rophy (P < 0.05 corrected for multiple voxel-wise comparisons within the prespecified anatomical regi

68 maximally discriminative for different group-wise comparisons, in each case revealing distinct enrich

69 m 30% per Brock to 71% per CTCAEv3 (all pair-wise comparisons, P < .01).

70 ta were further processed with post-hoc pair-wise comparisons.

71 -way analysis of variance with post hoc pair-wise comparisons.

72 rate a quantitative, user-independent, voxel-wise composite biomarker score (CBS) for detection of pr

73 However, the stage-wise computations therein remain poorly understood.

74 sychopathology were calculated using an item-wise confirmatory bifactor model, describing overall psy

75 ality of women who were alive at their final WISE contact date.

76 Voxel-wise contrasts against controls (at P < 0.05 family-wise

77 Voxel-wise contrasts between behavioural and dysexecutive Alzh

78 In voxel-wise contrasts, elevated Pittsburgh compound-B retention

79 ies of column-to-column transitions or block-wise contributions along the alignment.

80 n with PD: rs685012 (odds ratio = 1.32, gene-wise corrected p = .011) and rs10875995 (odds ratio = 1.

81 011) and rs10875995 (odds ratio = 1.26, gene-wise corrected p = .046).

82 Voxel-wise correlation analysis revealed that microglial activ

83 Voxel-wise correlation analysis suggests that neuroinflammatio

84 recovery of language was confirmed in voxel-wise correlation analysis, conducted unconstrained for t

85 Finally, pair-wise correlations between intraneuronal percentage chang

86 Furthermore, there were more strong pair-wise correlations of metabolite abundance in transgenic

87 surface and automatically establishes point-wise correspondence across faces.

88 singular value decomposition to extract pair-wise cosine values between the term (keyword) and miRNA

89 ples and is geared to help trialists steer a wise course in their statistical reporting, thereby givi

90 Functionality-wise cross-species analyses now enable users to analyse

91 An outer loop subject-wise cross-validation (CV) method evaluated the performa

92 etically encoded photo-crosslinkers and pair-wise crosslinking revealed distinct footprints of agonis

93 The WiSE-CRT system (EBR Systems, Sunnyvale, California) was

94 emonstrates the clinical feasibility for the WiSE-CRT system, and provided clinical benefits to a maj

95 assessing the safety and performance of the WiSE-CRT system.

96 bal volume expansion by amplifying component-wise deformations to global configurational change via t

97 This protocol provides a step-wise description of how to effectively use NetworkAnalys

98 says to further assess the predicted residue-wise determinants of distinct kinesin-microtubule bindin

99 d grey matter atrophy with significant voxel-wise differences in the cuneus, lingual and fusiform gyr

100 Here, we report the step-wise differentiation of human pluripotent stem cells (hP

101 erfering with this mechanism interrupts step-wise differentiation.

102 These stresses decrease as the stream-wise distance between plastron stagnation points increas

103 to achieve better consistency between sample-wise distances in the different profiles.

104 Specifically we compared probe-wise DNA methylation variance, and how this variance rel

105 palatal shelf elevation-80% of Pax9(del/del);Wise(-/-) double-mutant mouse embryos exhibit rescued pa

106 atforms (proteomic, genetic, etc) for system-wise drug target validation.

107 These genes were lost step-wise during the evolution of Scaptomyza.

108 he ACQ and AQLQ is not achievable as a group-wise efficacy threshold between treatment arms in clinic

109 e capable of continuous, as opposed to batch-wise, electroporation and cell analysis.

110 emporoparietal junction [TPJ]) encoded trial-wise empathy for beneficiaries, whereas the TPJ (but not

111 We posit that such step-wise engagement between Ire1 and its mRNA substrate cont

112 Furthermore, NC utilizes a step-wise, entropy-driven mechanism to trigger both residue-s

113 We also identified the gene-wise equivalent of GWS support for WDR88 (WD repeat-cont

114 ificance level p <= .05 corrected for family-wise error across the whole brain and within the insula.

115 s (all findings p<0.01 height, p<0.05 family-wise error cluster corrected).

116 and cerebellar WM pathways (P < .05, family-wise error corrected for multiple comparisons) and cervi

117 pared with healthy controls (P < 0.05 family-wise error corrected for total sodium concentration, P <

118 e balance performance (cluster level, family-wise error corrected P < .05, z threshold > 1.96) regard

119 Using voxel-based quantification (family-wise error corrected P < 0.05), we show the rate of whit

120 th the degree of spasticity (P < .05, family-wise error corrected) and cognitive impairment (r values

121 nts demonstrated significant (p<0.05; family-wise error corrected) fractional anisotropy reductions w

122 ntrasts against controls (at P < 0.05 family-wise error corrected) showed that (18)F-AV1451 and (18)F

123 s and cognitive improvement (P < .05, family-wise error corrected).

124 ietal regions and precuneus (P < .05, family-wise error corrected).

125 s and PD patients (voxelwise p < 0.05 family wise error corrected).

126 ed with the wait-list group (P < .05, family-wise error corrected); correlations were found between F

127 rbitofrontal cortices (cluster level, family-wise error corrected, P < .05, z threshold > 2.3).

128 ct-based spatial statistics: P < .05, family-wise error corrected; tractography: P values < .001 to .

129 After family-wise error correction across all traits (FWERacross), an

130 g ANCOVA (covariates, age and gender; family-wise error correction, P < 0.01).

131 statistically significant with a comparison-wise error of P < 0.01.

132 al clusters of significant coherence (family-wise error P < 0.01, voxel extent 1000).

133 ntrol the false discovery rate or the family-wise error rate (as defined later in this article).

134 on (empirical P < 0.001, FDR = 0.008, family-wise error rate = 0.008).

135 n developed, among which some control family-wise error rate and the others control false discovery r

136 cutoff that maintains control of the family-wise error rate via a correction factor to the significa

137 e putative mediators and controls the family wise error rate.

138 e matter tracts in both samples at 5% family-wise error-corrected thresholds.

139 d healthy control subjects (P < 0.05; family-wise error-corrected), mainly in the uncinate, cingulum

140 rnal capsule, and cerebellum (P<0.05, family-wise error-corrected).

141 a statistical threshold set at <0.05 (family-wise-error corrected).

142 We first quantified pixel-wise errors in the cropland classes of four widely used

143 Step-wise evaluation highlighted 20 proteins of possibly high

144 Our results suggest a step-wise evolutionary model in which Y. pestis emerged as a

145 is now able to go past the traditional gene-wise expression analyses in a variety of ways, analysing

146 Although coexpression analysis via pair-wise expression correlation is popularly used to elucida

147 of two beta roll molecules unfolds in a step-wise fashion mainly from the C terminal.

148 bly of the needle complex proceeds in a step-wise fashion that is initiated by the assembly of the ba

149 s of genomic cassettes are inserted, in step-wise fashion, into incomplete germ-line genes to generat

150 neuroblasts that generate neurons in a pair-wise fashion, with the two daughters providing the basis

151 TTP) were obtained in the placentas by voxel-wise fitting of the time series.

152 Whole-brain, voxel-wise functional connectivity was examined as a function

153 Furthermore, popular pair-wise gene evaluation methods, e.g. TSP and TSG, are help

154 d doublets are helpless for discovering pair-wise gene interactions, our approach can discover typica

155 acute nociceptive stimuli by applying a step-wise graded electrical forepaw stimulation paradigm, wit

156 associated with improved outcomes in a step-wise graded relationship (adjusted hazard ratio, 0.60; 9

157 Specifically, we modified the component-wise gradient boosting to improve the computational feas

158 lysis of primary end point components in the WISE group, compared with the historical control group,

159 Au309 cuboctahedral superatom model in shell-wise growth is illustrated.

160 rd VBM workflow involve establishing a voxel-wise hemispheric correspondence, capturing the direction

161 er mutations were highly related to the step-wise hepatocarcinogenesis because mutations were identif

162 Chromosome-wise heritability estimation was used to obtain further

163 gregation experiments, we demonstrate family-wise heterophilic specificity: All Dsgs form adhesive di

164 Step-wise identification of flavonoid classes is based on a U

165 ol phases during the LIA, followed by a step-wise increase from 1910 to present levels-unprecedented

166 The EhACK variants showed a step-wise increase in ADP and ATP binding but were still unab

167 The model suggests that a step-wise increase in daily administered primaquine dose woul

168 d for the kinetics of the response to a step-wise increase in irradiance from 100 to 600 micromol m(-

169 study for PhiPSII measured 1 h after a step-wise increase in irradiance identified several new candi

170 d with controls and also demonstrated a step-wise increase of biomarker concentrations over the conti

171 me of internal 0 g and 1 g controls and step-wise increase or decrease of the gravitational force in

172 In this method, a step-wise injection protocol of (64)CuCl2 and disulfiram was

173 Pair-wise inter- and intraobserver agreement was moderate (me

174 distance and orientation in evaluating pair-wise inter-residue interactions.

175 nd it only depends on the extent of the pair-wise interaction between different types of molecular cl

176 of seven genera as nodes and all of its pair-wise interactions among the bacteria are facilitative or

177 P and TSG, are helpless for discovering pair-wise interactions.

178 probe MSI, images are created through a grid-wise interrogation of individual spots by mass spectrome

179 creased elephant conservation is therefore a wise investment by governments in these regions.

180 Voxel-wise Jacobian determinant was estimated to elucidate vol

181 gnate codon-anticodon helix, initiating step-wise 'latching' of the decoding centre.

182 convergence by taking advantage of the block-wise LD structures in human genomes.

183 support vector machine approach using voxel-wise lesion likelihood values was used to show that it w

184 For each pair-wise lesion type comparison, linear discriminant analysi

185 It also outputs a file of input-tree-wise likelihood scores that can be used as input to CONS

186 Linear mixed effects and Bayesian piece-wise linear models were employed to test hypothesized re

187 In this research a piece-wise linear regression method was used for breakpoint de

188 Mixed-effects piece-wise linear regression was used to examine WMH differenc

189 Voxel-wise linear regressions thresholded at P < 0.05 (uncorre

190 ustment for missing data increases the group-wise linkage rates by 40-100%, and changes the relative

191 xample, kinesin-1 transports cargo in a step-wise manner along microtubules.

192 glide along the parent microtubule in a tip-wise manner.

193 Voxel-wise maps of [(11) C]PIB distribution volume ratio, refl

194 Vertex-wise maps of the association between gene expression lev

195 ve mean-variance test (IMVT) to combine gene-wise mean heterogeneity and variance heterogeneity induc

196 onnectivity and also survey a range of voxel-wise measures of intrinsic functional brain architecture

197 ing of this reaction proceeds through a step-wise mechanism taking place through a side-on nitroxyl O

198 icients are treated as the pixels of a block-wise megapixel sensor.

199 Voxel-wise meta-analyses of GMV or fMRI differences were perfo

200 We did pair-wise meta-analyses using the random-effects model and th

201 ent, we conducted the first multimodal voxel-wise meta-analysis of studies of voxel-based morphometry

202 methodological risks than conventional pair-wise meta-analysis.

203 ing (PRM), a novel computed tomography voxel-wise methodology, can offer insight into chronic allogra

204 Previous step-wise, Mg(2+)-dependent reconstitutions of Pfu RNase P wi

205 E, and TD x ACE were evaluated using a voxel-wise, mixed-effects, 2 x 2 ANOVA.

206 ic selectivity across the cortex using voxel-wise modelling of functional MRI (fMRI) data collected w

207 Subdivision-wise morphometric analysis found a significantly smaller

208 y and visual acuity were evaluated in a step-wise multivariable regression model, and the variables t

209 Multispectral imaging with object-wise multivariate image analysis was evaluated for its p

210 null model that preserves patient- and gene-wise mutation rates.

211 ing in nHGs prepared in the traditional step-wise (nHG-SW) approach and the one-pot (nHG-OP) process.

212 Histograms of pixel-wise optical redox ratio, defined as FAD/(FAD + NAD(P)H)

213 Globally and clock-hour sector-wise optimized BMO-based minimum rim area was calculated

214 mized minimum rim area (BMO-gMRA) and sector-wise optimized BMO-minimum rim area (BMO-MRA).

215 Quality-wise, our method at least matches quantum randomness exp

216 Voxel-wise overlap and subtraction analyses of lesions as well

217 l experiments with SHSs consisting of stream-wise parallel gratings, which confirm this numerical pre

218 Whole-brain voxel-wise parameter estimation confirmed these results.

219 Object-wise partial least squares discriminant analysis (PLS-DA

220 The model is characterized by the layer-wise path-dependent transmissibility over a contact, tha

221 These are arguments to consider a step-wise pathophysiology for these diseases, with therapy ad

222 Furthermore, the frequency-wise pattern of oscillation prevalence during teleportat

223 clustering method and are built into a pair-wise peak similarity score function.

224 Pair-wise Pearson's and polychoric correlations were calculat

225 tant for recognition by hPDI therefore, step-wise peptide Phe-to-Ala changes were progressively intro

226 rapping of single fluorescent proteins, step-wise photobleaching, and multiparameter spectroscopy, al

227 in murine tooth development, where Lrp4 and Wise play important roles.

228 ng Gata6 induction in mES cells reveals step-wise pluripotency factor disengagement, with initial rep

229 A "step-wise" preinitiation complex (PIC) assembly model has bee

230 We introduce a gene-wise prior and present a fully Bayesian formulation of a

231 ify DPN as an intermediate stage in the step-wise progression from nevus to melanoma.

232 th log-rank tests and then performed a piece-wise proportional hazards modeling with 2 time periods:

233 Voxel-wise R2 and R2* magnetic resonance (MR) imaging measurem

234 re dependent on BRCA1 that controls the step-wise recruitment of MRE11, FANCD2 and finally CtIP to st

235 We noted a step-wise reduction in survival with increasing number of tre

236 hy in RRMS increased incrementally with step-wise refinement to exclude ON effects; excluding eyes an

237 l gray matter asymmetries with a high (voxel-wise) regional specificity.

238 The integrated group-wise regularization methods increases the interpretabili

239 A key feature of meiosis is the step-wise removal of cohesin, the protein complex holding sis

240 to the least common species, leading to step-wise removal of previously dominant species.

241 Meeting delegates agreed on taking a step-wise roadmap for which the first output would be a conse

242 Twenty-seven seed-based voxel-wise rsFC data sets from 25 publications (556 individual

243 focal imaging enables investigation of depth-wise sectioned particle movements in the nanofluid dropl

244 scientific rigor toward a well-planned, step-wise sequence of preclinical and clinical studies, to de

245 effectively detect both individual and group-wise signals and outperforms the state-of-the-arts by a

246 ffectively capture both individual and group-wise signals that cannot be identified by the state-of-t

247 predicted change in LSAS over time, at study-wise significance (p=0.00833), with the minor allele ass

248 kelihood of remission at or just below study-wise significance (p=0.025): rs4606 (AOR=0.49 (95% CI=0.

249 , this effect was not significant at a study-wise significance level (Bonferroni threshold P < 5.8 x

250 We show how parallel searching of content-wise similar images in the dataset significantly reduces

251 Using pair-wise single-nucleotide polymorphism distances as a measu

252 resumably through its ability to bind to the Wise (Sostdc1)/sclerostin (Sost) family of Wnt antagonis

253 -edge subtraction, or alternatively by voxel-wise spectral fitting to give relative atomic concentrat

254 d tau181 (p-tau181) and amyloid-beta42 Voxel-wise statistical analyses examined spatial patterns of t

255 t-based spatial statistics to obtain a voxel-wise statistical analysis of the fractional anisotropy d

256 Connection-wise statistical analysis, as well as analysis of region

257 d Spatial Statistics (TBSS) to perform voxel-wise statistical comparison of fractional anisotropy (FA

258 ), and TCF7L2 (P = 5.10 x 10(-4)) with study-wise statistical significance.

259 Histologically uninformed multivariate voxel-wise statistics provided converging evidence for structu

260 After image quality control, voxel-wise statistics were performed on the diffusion paramete

261 Wise stewardship of the resources upon which we depend i

262 ed lineages, which are facilitated by a step-wise stratification of taxonomic groups.

263 WISE study (Wirion Study Europe) evaluated the safety an

264 The WISE study (Women's Ischemia Syndrome Evaluation) was a

265 A 2x2 analysis of variance using voxel-wise subsampling permutation tests compared the interact

266 The voxel-wise subtraction analysis showed associations between st

267 ents' post- to pretreatment images and voxel-wise subtraction between Gaussian-normalized relative ce

268 Voxel-wise subtraction of SL-off from SL-on images enabled the

269 on van der Waals-London forces based on pair-wise summation of dipole-dipole interactions across an i

270 We also analyzed the region-wise SUVRs of both uncorrected and corrected images.

271 ions, our approach can discover typical pair-wise synergic genes efficiently.

272 Several efforts to discover pair-wise synergy have been made based on the information app

273 MIC(X1; X2; Y) is employed to detect pair-wise synergy in simulation and cancer microarray data.

274 The modular and step-wise synthesis of peptoid polymers, on the other hand, a

275 Using voxel-wise t-test statistics, we showed associations between d

276 scribe a haplotype-based framework for group-wise TDT (gTDT) that is flexible to encompass a variety

277 evel observations from in vivo MRI and voxel-wise tensor based morphometry.

278 We here propose a unified marker wise test (uFineMap) to accurately localize causal loci

279 A step-wise, 'test-all-positive-gluten' analytical methodology

280 ple interacting causal agents assembled step-wise through a tree.

281 It seems wise to conduct better surveillance for novel influenza

282 , commonly used in electronic devices, it is wise to investigate if curling polarization structures a

283 - and biexponential models were fitted pixel-wise to the series of T1rho and T2 weighted images.

284 Point-wise total deviation values were recorded from the stati

285 his process is superior to a comparable step-wise traditional approach and circumvents loading of the

286 Their step-wise transcriptional activation follows their genomic to

287 whereas the expression of TF leads to a step-wise transition to latent and overt tumor growth phases,

288 opose that Rad4 recognizes lesions in a step-wise "twist-open" mechanism, in which preliminary twisti

289 ential gatekeeping strategy controlled study-wise type 1 error for serum ferritin, transferrin satura

290 ese methods, assessed on the basis of family-wise type I error rate and power, depends on underlying

291 alse discovery rate (FDR), instead of family-wise type I error rate, is controlled for the multiple t

292 study elucidates a complex mechanism of step-wise ubiquitination and deubiquitination activities that

293 r cholinergic stimulation affected the trial-wise updating of probabilistic beliefs that underlie the

294 quired to ensure improvement in outcomes and wise use of resources.

295 though both tissues showed appreciable probe-wise variability, the specific regions and magnitude of

296 y of food samples was low, but exhibited lot-wise variation.

297 Two approaches, pixel-wise and object-wise, were investigated to group kernels according to ha

298 eover, we found that genetic inactivation of Wise, which is expressed in the developing palatal shelv

299 Voxel-wise whole brain comparisons using tract-based spatial s

300 Voxel-wise, whole-brain analysis revealed enhanced rCBF only i