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2 mixed multiple-species infections as well), with an overall 100% agreement with matrix-assisted lase
3 /- 0.3% at a contamination of 0.1 +/- 0.03%, with an overall 25.7 +/- 1.7-fold concentration of the r
4 ears lived with disability increased by 32%, with an overall 28% reduction in disability-adjusted lif
5 ncreatic cancer has a devastating prognosis, with an overall 5-year survival rate of 8%, restricted
9 eltamivir increases the likelihood of death, with an overall 75% increase in the adjusted odds ratio
10 shock, 9 (6-22) versus 11 (6-24), P = 0.64; with an overall 90-day all-cause mortality of 35 (18%) v
13 lastic polyps (specificity 0.89; 0.78-0.95), with an overall accuracy of 241 of 260 (0.93, 0.89-0.96)
15 nts would be diagnosed with ASD at 24 months with an overall accuracy of 69% and corresponding 66% se
17 isolate, and 36 (13.0%) other CoNS isolates, with an overall accuracy of 80.1% compared to an API STA
19 resampling technique, identified variant VWD with an overall accuracy of 88.1%, which predicts the as
20 ED differentiated cancers from benign tumors with an overall accuracy of 90% (27 of 30) on the test s
21 dentified oestrogen-receptor-positive status with an overall accuracy of 90% (training set), 88% (fir
23 e to identify type 1C, 2A, 2B, 2M, or 2N VWD with an overall accuracy of 92.5% in the patient study c
25 the 32 serotypes ranged from 68.8% to 99.9%, with an overall accuracy of 96.0% for the random forest
26 sification, and ranged from 67.8% to 100.0%, with an overall accuracy of 96.1% for the support vector
29 nt according to standard evaluation metrics, with an overall accuracy of over 74% estimated using mul
30 clic series yielded compound 2s (BMS-767778) with an overall activity, selectivity, efficacy, PK, and
31 lower scores were found with PSC opacities, with an overall adjusted mean difference of 6 points (95
32 tal health, and color and peripheral vision, with an overall adjusted mean difference of approximatel
35 1.1-1.9x10(5)M(-1) and nonsaturable binding with an overall affinity constant (n K(a)) of 3.7-4.1x10
38 interpretation for past or recent infection, with an overall agreement of 99% (95% confidence interva
39 ion, the optimal z score threshold was 2.41, with an overall agreement with visual interpretation in
40 total of 268 incident cases were identified, with an overall annual age- and sex-adjusted incidence o
41 nts during posttreatment long-term follow-up with an overall annual event rate of 2.5% (4.9% in cirrh
43 n consists of 12 transmembrane helices (TMs) with an overall architecture similar to that of the dist
44 helical, two-domain, seahorse-like structure with an overall architecture unlike any previously descr
46 detect urinary black carbon in all children, with an overall average (SD) of 98.2 x 10(5) (29.8 x 10(
48 gnificantly different death rates (p=0.021), with an overall average mortality reduction of 20% (-2 t
50 is highly similar to that of ZEBOV VP35 IID, with an overall backbone r.m.s.d. of 0.64 A, but contain
51 ed increased antigen-specific antibody titer with an overall balanced Th1/Th2 response, while the dua
52 a Mobius bond-shift transition state to 11, with an overall barrier of 29.8 kcal/mol at the CASPT2(1
53 of the E-Se-OH prefers a stepwise mechanism with an overall barrier of 6.9 (11.3) kcal/mol, which is
54 c evaluation in suspected EVH was associated with an overall benefit in visibility, duration of the p
55 ximal inhibition constants (IC50s) than FCM, with an overall bias of 2.2-fold (Bland-Altman compariso
57 3846 K. pneumoniae cultures were identified, with an overall carbapenem resistance rate of 24.6%.
63 static, iodine-refractory thyroid carcinoma, with an overall clinical benefit rate (partial response
64 romote CTC cluster formation within 2 weeks, with an overall cluster formation success rate of approx
66 .24 mg/kg/d in combination with chemotherapy with an overall complete remission and complete remissio
67 um and it is part of a novel protein complex with an overall composition overlapping with but differe
68 nt 7 in a cohort of prostate cancer patients with an overall concordance of 92% between fresh and pre
69 orrectly reported 74 out of 75 allelic pairs with an overall concordance rate of 99% compared with co
70 ndent gating that reconcile how ion channels with an overall conserved transmembrane architecture may
71 undwater via multiple successive extractions with an overall consumption of 4 being 9:1 in terms of [
72 rons and stimulation effects were consistent with an overall contraversive drive, with varying outcom
73 clear separation among the four onion groups with an overall correct classification rate (CR) of 97.5
74 significant reduction of caspofungin usage, with an overall cost savings of 1,729 US dollars per pat
77 with N-succinimidyl-4-(18)F-fluorobenzoate, with an overall decay-corrected radiochemical yield of 1
78 irst and second affected siblings consistent with an overall decline in function as indicated by the
79 to transcribe viral genomes, which coincided with an overall decrease in cellular gene expression.
80 d L1 expression observed in iPSCs correlates with an overall decrease in CpG methylation in the L1 pr
81 1) homozygosity was significantly associated with an overall decrease in LP compared with heterozygos
82 cell infiltration of recipient intestine and with an overall decrease in pathologic scores in intesti
84 not Chinese medicinal herbs, were associated with an overall decrease in the frequency of vasomotor s
85 ancer are performed on the aging population, with an overall decrease in the number of cases performe
86 ng other oxygen-containing functional groups with an overall decrease in total surface oxygen content
87 This Grk5 morphant phenotype was associated with an overall decrease of early cardiac progenitors as
89 howing that the MEC network always responded with an overall depolarization, indicative for net excit
90 .35), 0.23 (CI, 0.15 to 0.33), respectively, with an overall diagnostic accuracy of 95% (CI, 93% to 9
91 001, respectively) after 24 hours of cooling with an overall difference of 556 dynes m(2)/s per cm(5)
94 nicks due to mobility of a collision complex with an overall DNA-binding footprint of approximately 3
97 ting caregiver reactions to these behaviors, with an overall effect size of 0.15 (95% CI=0.04-0.26; z
98 ucing behavioral and psychological symptoms, with an overall effect size of 0.34 (95% CI=0.20-0.48; z
99 uced maternal febrile influenza-like illness with an overall efficacy of 19% (95% CI 1 to 34) in the
101 ergic disease, SHS in infancy was associated with an overall elevated risk of eczema with sensitizati
103 ation remained stable between 2001 and 2011, with an overall estimate of 93.7 cases per 100000 person
104 the United Kingdom and Republic of Ireland, with an overall estimated seroprevalence of 50% (n = 314
106 ne (PCP) markedly disrupts neuronal activity with an overall excitatory effect and reduces the power
107 rbohydrate and sugar intakes, are associated with an overall favorable lipoprotein profile in terms o
109 (equivalent to 70.8 kg y(-1)) using a system with an overall footprint of half the size of a standard
112 r is achieved via Hoogsteen hydrogen bonding with an overall geometry that is well poised for catalys
113 etene imines have been applied are presented with an overall goal of inspiring new uses for these und
114 cular dynamics with the Jarzynski estimator, with an overall good agreement between the three methods
117 er liver transplantation was well tolerated, with an overall high SVR12 rate (85%) including patients
121 on variable positions (MVPs) were identified with an overall hypomethylation in psoriasis patient sam
122 and 97.4% specificity (95% CI, 97.2-97.6%), with an overall improved accuracy (chi = 398; p < 0.001)
127 entified 1053 episodes of cryptosporidiosis, with an overall incidence of 0.86 infections per child-y
128 hemia due to severe atherosclerotic disease, with an overall incidence of 100 per million people in t
129 rt failure hospitalization during follow-up, with an overall incidence of 11.1%, 16.9%, and 24.6% at
130 ts, 384 had evidence of SUD during training, with an overall incidence of 2.16 (95% CI, 1.95-2.39) pe
132 ed or screen-detected) diabetes at baseline, with an overall incidence rate of 2.8 per 1,000 person-y
133 p [PYFU], 16 patients seroconverted for HDV, with an overall incidence rate of 9.07 per 1000 PYFU, wh
134 These behavioral changes were associated with an overall increase in activity of PFC neurons and
135 England over the past decade were associated with an overall increase in adverse surgical outcomes.
136 ) were observed over time from 1990 to 2008, with an overall increase in lower-stage disease detectio
138 entral retinal vein occlusion was associated with an overall increase in mortality compared with cont
141 to increased energy supply and is associated with an overall increase in volumetric growth and elonga
142 horter breastfeeding duration was associated with an overall increased risk of eczema (P-value for tr
143 slow-binding inhibitor of its parent enzyme, with an overall inhibition constant in the low nanomolar
144 of human ADAM9 catalytic/disintegrin domain with an overall inhibition constant of 280 +/- 34 nM and
145 e enantiopure natural product in three steps with an overall isolated yield of 32% from the amino aci
146 ingle site; however, this binding is complex with an overall K(d) of 46 microM, but also showing a re
147 e of free charge-carrier generation combined with an overall larger amount of free charges, meaning t
151 be greatly reduced in size and gene content with an overall locus organization differing from that o
157 through a series of repeating uniform steps with an overall macroscopic processivity (P) of 0.90 +/-
158 gher in men than in women in all age groups, with an overall male-female prevalence ratio of 1.5.
159 howing excellent analytical figures of merit with an overall maximum bias of 5.8%, very high precisio
160 Participants in both groups gained weight, with an overall mean +/- SD weight gain of 1.24 +/- 2.03
161 scaling predicted adolescent drug clearance with an overall mean absolute percentage error of 17.0%.
162 e geometric features of the original CT data with an overall mean deviation of less than 2 mm, indica
164 than the nominal density of metallic silver, with an overall mean value of 7900 +/- 675 kg m(-3).
165 ng 17600 patients included, 10 862 were men, with an overall median age of 59 years (range, 51-68 yea
167 ndividuals from three United Kingdom cohorts with an overall meta-analysis P value of 1.1 x 10(-11).
169 esumptive MT cells recorded extracellularly, with an overall modest increase in resting and odorant-e
170 embolic stroke was seen in 7 patients (16%) with an overall mortality in this subpopulation of 42% (
175 s than 5 ng/L in 594 (56%) of 1061 patients, with an overall negative predictive value of 99.4% (98.8
176 rom being a source to being a sink of N(2)O, with an overall net uptake during the experimental perio
177 , a switch toward the C-terminus is observed with an overall nonmonotonic change of the dimerization
178 mcitabine-refractory patients was associated with an overall objective radiologic response rate of 10
179 pembrolizumab administration was associated with an overall objective response rate of 33%, 12-month
180 nificantly associated with familial BC risk, with an overall odds ratio (OR) of 2.05 (95% CI, 0.94-4.
182 gave a final 2 SNP (D165N and p-2502) model with an overall odds ratio of 2.45 (95% confidence inter
183 se in each of the seven populations studied, with an overall P value of 2.1 x 10(-8) under a recessiv
184 ng each of seven study populations examined, with an overall P=3.2 x 10(-7) from a combined allelic t
185 nsive multikilobase contacts with chromatin, with an overall pattern similar to that of wild-type Yan
186 olved in proliferation and immunoregulation, with an overall pattern that bears hallmarks of T cell e
187 = 0.0001) with the manual microscopy counts with an overall Pearson correlation of 0.96 across the t
188 rately predicted the N-terminal acetylation, with an overall performance comparable or superior to th
189 findings of normal learning rate concurrent with an overall performance deficit in patients with sch
192 41 candidate genes, and CNVs in 10 families, with an overall potential molecular cause identified in
194 the most common inherited cardiac disorder, with an overall prevalence of at least 1:500 in the adul
196 through a series of repeating uniform steps with an overall processivity of P = 0.949 +/- 0.003; thi
197 iacylglycerides directly from synthesis gas, with an overall productivity of 0.19 gL(-1)h(-1) and a l
201 H(A)- --> P+ Q(A)-) in approximately 200 ps, with an overall quantum yield of approximately 100%.
203 od test-retest reliability was demonstrated, with an overall r = 0.72 and all individual subtest corr
204 tomated radiosynthesis process within 57 min with an overall radiochemical yield of 21%, decay-correc
205 ponses, MAPK signaling, and Ca(2+) signaling with an overall rank order of potency of 2-f-LIGRLO-NH(2
206 lted in high rates of virologic suppression, with an overall rate of mother-to-child transmission of
208 sociated with ClpP, translocates polypeptide with an overall rate of ~35 aa s(-1) and, on average, tr
209 see variations in the degree of dissolution with an overall reaction rate which is approximately 14
210 ,225)Ra from the thorium matrix was obtained with an overall recovery yield of 91 +/- 3%, average rad
211 pathologic evidence of tumor at the margin, with an overall recurrence rate of 7.1% at 1 year, 2 yea
212 ze the assembly of PGLa into a toroidal pore with an overall reduced charge density, which could expl
213 oral anticoagulants are uniformly associated with an overall reduced risk of ICH when used for stroke
216 dition, doxycycline treatment was associated with an overall reduction in the expression and activity
217 severe exacerbation (282 days vs. 226 days), with an overall reduction of 21% in the risk of a severe
219 predictive capability of FT-EoS was observed with an overall relative absolute average deviation clos
220 etween fiber intake and all-cause mortality, with an overall relative risk of 0.84 (95% confidence in
221 and Aspergillus was 200 copies per reaction, with an overall reproducibility of 92.1% for detecting 2
225 ponse, defined as the proportion of patients with an overall response per investigator's assessment a
226 enty-seven patients were treated with R-CHOP with an overall response rate of 100% (complete response
227 ON Everolimus has high single-agent activity with an overall response rate of 70% and manageable toxi
228 T-cell lymphoma and lymphomatoid papulosis, with an overall response rate of 73% and complete respon
231 , and to estimate the proportion of patients with an overall response that was equal to a partial res
232 (IQR 17.5-18.9), the proportion of patients with an overall response was 28 [90%] of 31 (22 [71%] of
233 y objectives were the proportion of patients with an overall response, progression-free survival, ove
236 yses reveal that mTORC1 is an obligate dimer with an overall rhomboid shape and a central cavity.
237 ver a mean period of 48.01 +/- 71.99 months, with an overall risk ratio of 0.96 (95% confidence inter
238 ixed-backbone model performs reasonably well with an overall rmsd between computed and predicted side
239 rates were 14.87 (control) and 11.27 (IAI), with an overall RR of 0.76 (95% CI, 0.65-0.89); HTN rate
241 was able to predict relapse in 60% of cases with an overall sensitivity and specificity of 60% and 9
242 .6%) concordance with those of the HC2 test, with an overall sensitivity and specificity of 96% for t
243 d T1-weighted imaging depicted 13 of 19 HCCs with an overall sensitivity of 68.4% (13 of 19) and spec
244 ranscriptional RNA from the genomic sequence with an overall sensitivity of 91% and a specificity of
245 by RMA, and all target viruses were detected with an overall sensitivity of 94% and specificity of 99
246 ma, and pituitary), which were discriminated with an overall sensitivity of 99.4% and a specificity o
248 -bonding pattern such that a base pair forms with an overall shape that is virtually indistinguishabl
249 ecies and its close relatives was associated with an overall shift in the fraction of genes devoted t
250 in the past 2 decades but was not associated with an overall shift toward higher-staged cancers, ques
251 protection factor changes are not associated with an overall shortening of hydrogen bonds in the prot
252 Management of AC has improved with time, with an overall shorter hospital length of stay, lower r
253 blished for the first time in three subjects with an overall significant mean improvement in stereoac
254 ndance had significantly fewer ribosomes but with an overall similar distribution under hypoxia, cons
255 e ice sheet size was smaller than today, but with an overall similar to modern global hydrological cy
257 all 219 ATL samples (sensitivity of 100.0%) with an overall specificity of 93.9% (considering health
259 and a functional APE1-substrate DNA complex with an overall stoichiometry of one Mg(2+) per mole of
260 Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-bin
261 and less frequent mutations in other genes, with an overall study concordance of 50.4% and sensitivi
262 several genes including EGFR, KRAS, and TP53 with an overall study concordance of 78.1% and sensitivi
265 oth reduced as DOC concentrations increased, with an overall suppression of I2 emissions of about a f
266 nt improvement in progression-free survival, with an overall survival benefit at the interim analysis
272 rely cured by currently available therapies, with an overall survival rate of approximately 10%.
274 t-order dependence on catalyst concentration with an overall third-order rate constant (k) of 184 +/-
277 ynthesis of biologically essential vitamins, with an overall twofold up-regulation of expression comp
278 rted within the 2 years after trial closure, with an overall unadjusted relative risk of 1.50 (95% CI
279 ook up OCS during most of the growing season with an overall uptake of 1.36 +/- 0.01 mol OCS per ha (
282 ce (PL) and ECL emission from blue to green, with an overall wavelength span of 73 (PL) and 67 (ECL)
284 2) and pseudoisocytidine (24), respectively, with an overall yield of 15.9% (six steps) and 37.9% (fo
286 d stereoselective synthesis of 1 in 10 steps with an overall yield of 24% from readily available benz
289 haride backbone was successfully constructed with an overall yield of 37% from disaccharide building
291 y available starting materials in five steps with an overall yield of 40% and without any column chro
293 he title compound is prepared in seven steps with an overall yield of 41% starting from geraniol.
294 he synthesis was achieved in 10 linear steps with an overall yield of 6.4% starting from (+)-dehydroi
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