ライフサイエンスコーパス: with high affinity (for|to)

1 Our hypothesis that a drug with high affinity for 5-HT2CR, such as clozapine, would

2 that has been shown to bind specifically and with high affinity to 5'-untranslated regions of yeast m

3 However, TFIIIA binds with high affinity to 5S nucleosomes lacking the N-termi

4 a distinctive population of hunter-gatherers with high affinity to a approximately 24,000-year-old Si

5 containing the critical c-Rel residues bound with high affinity to a broader range of NF-kappaB recog

6 B cells mutate their BCR to identify new Abs with high affinity to a challenging Ag.

7 OMA-1 binds with high affinity to a conserved region of the glp-1 3'

8 10E8 binds with high affinity to a construct mimicking the fusion i

9 CodY was found to bind with high affinity to a DNA fragment containing the prom

10 In addition, His-tagged CouR bound with high affinity to a DNA fragment encompassing the co

11 d to obtain a large variety of Abs that bind with high affinity to a given antigen.

12 Ly49H binds with high affinity to a mouse cytomegalovirus (MCMV)-enc

13 he FHA domain of PNK binds specifically, and with high affinity to a multiply phosphorylated motif in

14 Alternatively, LAs may bind with high affinity to a native slow-inactivated state, t

15 The CatL-cleaved ZEBOV-GP intermediate bound with high affinity to a neutralizing antibody, KZ52, and

16 AT utilises an induced-fit mechanism to bind with high affinity to a pentasaccharide sequence found i

17 roducts of the IL18R1 and IL18RAP genes, and with high affinity to a separate IL-18 binding protein (

18 we describe includes (i) selection of scFvs with high affinity for Abeta42 fibrils after removal of

19 While several protein based inhibitors with high affinity for activated FXII (FXIIa) were devel

20 ed and evaluated (18)F-JNJ64349311, a tracer with high affinity for aggregated tau (inhibition consta

21 bited a pansomatostatin-like profile binding with high affinity to all five hsst1-hsst5 subtypes (IC5

22 cortin 1 receptor (MC1R), whereas ASIP binds with high affinity to all three receptors.

23 Protein M binds with high affinity to all types of human and nonhuman im

24 A pentapeptide, Gly-Pro-Arg-Pro-Pro, with high affinity for alpha-chain-fibrin was labeled wi

25 nephrine and a number of compounds that bind with high affinity to alpha2-ARs.

26 P with the peptide sequence RGD, which binds with high affinity to alphaVbeta3 integrins present in b

27 ed cystine knot (knottin) peptide that binds with high affinity to alphavbeta3, alphavbeta5, and alph

28 rmore, we found that DRB1*1501 protein binds with high affinity to amino acid sequences of sense-PR3,

29 e results suggest that the radioligand binds with high affinity to an agonist conformation of the rec

30 n of MPER peptides indicate that Z13e1 binds with high affinity to an epitope between and overlapping

31 the GFLD in complex with a copper ion bound with high affinity to an extended hairpin loop at the di

32 stromal domain of the Alb3 translocase binds with high affinity to and regulates GTP hydrolysis in th

33 hemical system, MMP-2, MMP-3, and MMP-9 bind with high affinity to, and are activated by, specific sm

34 We previously reported that beta2GPI binds with high affinity to annexin A2 on the endothelial surf

35 ation of deleting cells expressing receptors with high affinity for antigen with anergy of the undele

36 he major PKA phosphorylation sites and binds with high affinity to AP2 only when dephosphorylated, di

37 63), a type II transmembrane receptor, binds with high affinity to APF.

38 Abeta12-28P binds with high affinity to apoE, preventing its binding to Ab

39 GBC binds with high affinity to aporeceptors, presumably in the in

40 cluster glycopeptides (e.g., triGalNAc) bind with high affinity to ASGP-R and, when conjugated to a t

41 ast extracts as a protein complex that binds with high affinity to autonomously replicating sequences

42 These synthetic Fabs bind with high affinity to BAX and inhibit its activation by

43 The small molecule inhibitor ABT-737 binds with high affinity to BCL-2, BCL-XL, and BCL-W but with

44 1 diabetes, we designed a new I-Ag7 tetramer with high affinity for BDC-5.2.9 that contains the pepti

45 Galectin-1 (gal-1), a special lectin with high affinity to beta-galactosides, is implicated i

46 adiotracer Pittsburgh Compound-B (PiB) binds with high affinity to beta-pleated sheet aggregates of t

47 t binds the barbed end of the actin filament with high affinity to block further filament elongation.

48 lin ECD-Fc bound directly, specifically, and with high affinity to bone morphogenetic proteins 9 and

49 s study were single-chain Fv domains (scFvs) with high affinity for BoNT serotype A (BoNT/A).

50 Btr binds with high affinity to both apo-BB and Fe-BB, and the res

51 ITC) was used to demonstrate that CusF binds with high affinity to both Cu(I) and Ag(I) but not Cu(II

52 hosphorylation-independent mutants that bind with high affinity to both P-Rh* and light-activated unp

53 perlecan and endorepellin bind directly and with high affinity to both VEGF receptors 1 and 2, in a

54 ting to identify several variants that bound with high affinity to both VEGFR2 and alpha(v)beta(3) in

55 e M. xanthus PilB possesses conserved motifs with high affinity for c-di-GMP binding, the findings he

56 tose apoptotic neurons and that Megf10 binds with high affinity to C1q, an eat-me signal for apoptoti

57 identifying additional fluorescent molecules with high-affinity for C3d that will subsequently be exp

58 It binds with high affinity to Ca2+ channel alpha2delta subunits

59 titration calorimetry showed that DPTL binds with high affinity to carbocyclic TXA(2), TXA(2) mimetic

60 log of SS-31 to demonstrate that SS-31 binds with high affinity to cardiolipin, an anionic phospholip

61 measurements revealed that fatty acids bind with high affinity to ccd-Angptl4.

62 CCX-CKR is an atypical chemokine receptor with high affinity for CCL19, CCL21, and CCL25 chemokine

63 CCL18 bound with high affinity to CCR8 and induced its internalizati

64 he glycolipid alpha-galactosylceramide binds with high affinity to CD1d and stimulates natural killer

65 imer's disease (AD) pathophysiology and bind with high affinity to cellular prion protein (PrP(C)).

66 module (CBM) from Clostridium thermocellum, with high affinity to cellulose, and the ZZ fragment of

67 the thiol peptide RGDC, a ligand that binds with high affinity to certain integrin receptors.

68 encodes a secreted 44-kDa protein that binds with high affinity to certain murine and human chemokine

69 21, itself a class I MHC-like protein, binds with high affinity to class I MHC molecules as a tetrame

70 ain of ClpA, only one molecule of ClpS binds with high affinity to ClpA hexamers (ClpA(6)).

71 The composition of polymers with high affinity for cocaine was optimised using molec

72 the basic region (BR) of the B-domain binds with high affinity to cofactor-like FV(a) variants that

73 omain of TbetaRI (TbetaRI-ED) binds in vitro with high affinity to complexes of the extracellular dom

74 Moloney murine leukemia virus (MLV) can bind with high affinity to conserved UCUG elements within the

75 fied multiple regions in the pre-genomic RNA with high affinity for core protein dimers.

76 Two novel compounds with high affinity to COX-2 (6k = 70 nM, 8e = 60 nM) hav

77 cy and were found to be selective inhibitors with high affinity to COX-2 (IC50 ranging from 20-2500 n

78 5TR1) as a recognition layer led to a sensor with high affinity for CT26 cancer cells, compared to co

79 Here we show that p17 binds with high affinity to CXCR2, a CXCR1-related receptor, a

80 a humanized antibody that selectively binds with high affinity to CXCR4, an antigen that is selectiv

81 A) and its nonimmunosuppressive analogs bind with high affinity to CypA and inhibit HIV-1 replication

82 red buspirone, a D2-like receptor antagonist with high affinity for D3 and D4 receptors, on the relat

83 e binding loop of aprotinin, a small protein with high affinity for DENV protease.

84 two N-terminally directed antibodies, bound with high affinity to deposited forms of Abeta, whereas

85 ce-activated cell sorting to identify clones with high affinity to detergent-solubilized alpha(v)beta

86 ucleotide exchange factor for Ras that binds with high affinity to diacylglycerol analogs like the ph

87 ptor transgenic CD8 T cell populations, each with high affinity for different peptides presented by d

88 RI binds with high affinity to diverse secretory ribonucleases (R

89 bilizing an ATP-induced conformational state with high affinity for DNA, whereas the chi subunit does

90 The g5p also binds with high affinity to DNA and RNA sequences that form G-

91 he borrelial PUR domain protein, Bpur, binds with high affinity to double-stranded DNA adjacent to th

92 ), which is encoded by the BANF1 gene, binds with high-affinity to double-stranded DNA and LEM domain

93 It binds with high affinity to E-box elements and, through intera

94 with heparan sulfate-FGFR4 to form a complex with high affinity for endocrine FGF19 but also impacts

95 Recombinant progranulin bound with high affinity to EphA2 in both solid phase and solu

96 We report here that gHgL binds with high affinity to epithelial cells and that affinity

97 16 (LY2066948-HCl) binds with high affinity to estrogen receptors alpha and beta

98 Monomeric frataxin binds with high affinity to ferrochelatase, the enzyme involve

99 ed, the two individual polypeptides interact with high affinity to form a stable heterodimer.

100 ovel cationic bolaamphiphile that binds TFDs with high affinity to form self-assembled complexes (nan

101 in A4 (LXA4, 0.02-2 microM, a lipid mediator with high affinity for Fpr-rs1) mimicked the inhibitory

102 IHF, but not its DNA-binding variants, binds with high affinity to fragments containing attB and attP

103 s and amino acids on the Ad5 hexon that bind with high affinity to FX thereby better defining adenovi

104 MutSalpha binds with high affinity to G4 DNA formed upon transcription o

105 persistently open GABA(A) receptors on DGCs with high affinity for GABA, slow desensitization rate,

106 se data show that chemokine-derived peptides with high affinity for GAGs may be used as anti-inflamma

107 identify a novel peptide sequence that binds with high affinity to Galpha(i1).

108 t regulates red blood cell development binds with high affinity to GATA motifs, and initial studies s

109 Furthermore, we find that GDF15 binds with high affinity to GDNF family receptor alpha-like (G

110 from a llama heavy chain antibody that binds with high affinity to GFP as well as to some GFP variant

111 By contrast, the CI-MPR bound with high affinity to glycans containing either phospho-

112 ension-dependent local transition to a state with high affinity for GPIbalpha.

113 l-molecule tracer for PET imaging that binds with high affinity to GPIIb/IIIa receptors and has suita

114 ed antagonist, [(3)H]G9543, was able to bind with high affinity to GPR84, this was not competed for b

115 OMB1 is a novel DOTA-coupled GRPR antagonist with high affinity for GRPR and excellent in vivo stabil

116 4) and SarAr-SA-Aoc-GSG-bombesin(7-14) bound with high affinity to GRPR with an inhibitory concentrat

117 (64)Cu-SarAr-SA-Aoc-GSG-bombesin(7-14) bound with high affinity to GRPR-expressing cells and that the

118 4 amino acids and binds with selectivity and with high affinity to GRPRs.

119 9A is a mouse inhibitory receptor that binds with high affinity to H2(d) in both a cis- and trans-man

120 specific for methyl-CpG dinucleotides, bind with high affinity to halogenated pyrimidine lesions, pr

121 ng these binding mutations produced a mutant with high affinity for hapten but exceptionally low stab

122 This collagen binds with high affinity to heparan sulfate through a unique b

123 d on liver sinusoids, has been shown to bind with high affinity to hepatitis C virus (HCV) E2 glycopr

124 /heparin and dermatan sulfate (DS) both bind with high affinity to hepatocyte growth factor/scatter f

125 as a recognition layer resulted in a sensor with high affinity for HepG2 cancer cells in comparison

126 etylcholine receptors (nAChRs) and both bind with high affinity to heteromeric alpha3beta4 and alpha4

127 ng giant lipid vesicles that contain domains with high affinity for his-tagged proteins, we show that

128 Peptides from the isoform BAX-delta bound with high affinity to HLA-A*0201 and HLA-DR1.

129 To enter cells, they must bind with high affinity to host cell receptors and then uncou

130 emains unidentified, we show that FplA binds with high affinity to host phosphoinositide-signaling li

131 804, a peptide-based molecular imaging agent with high affinity for human c-Met, for the detection of

132 ering T cells to express a chimeric receptor with high affinity for human mesothelin.

133 (3)H-MK-6240 bound with high affinity to human AD brain cortex homogenates

134 tazolamide (AZM) is a sulfonamide that binds with high affinity to human CA isoform II (HCA II).

135 variable antibody fragment (scFv) that binds with high affinity to human PECAM-1 and cross-reacts wit

136 hark, named E06, that binds specifically and with high affinity to human, mouse, and rat serum albumi

137 (P1-1) and GSTA1-1 (A1-1) are shown to bind with high affinity to HYP and to differentially quench i

138 F EfbA and confirmed that this protein binds with high affinity to immobilized fibronectin, collagen

139 By contrast, PB2 can only bind with high affinity to importin alpha5 in the absence of

140 ion, provides a mechanism for generating Abs with high affinity for invading pathogens.

141 initiation factor (eIF)4F binds specifically with high affinity to IRE-RNA; (iv) Fe(2+) increased eIF

142 binding studies indicated that lysine bound with high affinity to its binding site as an inhibitor.

143 d messenger diacylglycerol (DAG), which bind with high affinity to its C1 domain and promote beta2-ch

144 In skeletal muscle, agrin binds with high affinity to laminin(s) and alpha-dystroglycan

145 mone releasing hormone (LHRH), AN-207, binds with high affinity to LHRH receptors and can be targeted

146 he absence of membranes, but that also binds with high affinity to lipid micelles and bilayers in the

147 lymyxin B (PMB), a cyclic peptide antibiotic with high affinity for LPS.

148 succinylated concanavalin A, a plant lectin with high affinity for mannose, revealed that Acanthamoe

149 that underpins the ability of HSPGs to bind with high affinity to many different proteins, including

150 hree-helix-bundle domains that can each bind with high affinity to many host proteins such as antibod

151 the first rationally designed small molecule with high affinity for Mcl-1, Bcl-x(L), and Bcl-2.

152 cell-surface glycoproteins that bind folate with high affinity to mediate cellular uptake of folate.

153 ain within Amot is shown to selectively bind with high affinity to membranes containing monophosphory

154 ZBTB4 is a mammalian epigenetic regulator with high affinity for methylated CpGs that localizes at

155 ghlight the importance of targeting peptides with high affinity for MHC class I when designing T cell

156 mmunotherapy have focused on peptide ligands with high affinity for MHC class I.

157 ll, our results indicate that eribulin binds with high affinity to microtubule plus ends and thereby

158 Gremlin-1 binds with high affinity to MIF (KD = 54 nm), as evidenced by

159 that purified recombinant Brd4(1-720) binds with high affinity to MLV integrase and stimulates corre

160 hatidic acid, and cholesterol, bind to TRPV1 with high affinity to modulate channel gating.

161 ly represents a stage of the transport cycle with high affinity for monovalent cations and low affini

162 mmaRI or CD64) is the sole human Fc receptor with high affinity for monovalent IgG.

163 ssant effects of buprenorphine (BPN), a drug with high affinity for mu opioid receptor (MORs) and kap

164 We find interactions consistent with high affinity for multiple forms of Abeta, particul

165 MABT bound with high affinity to multiple forms of Abeta, protected

166 The IE62918-927 peptide bound with high affinity to multiple HLA-DR alleles and was re

167 -1c to be an effective glutamate transporter with high affinity for Na(+) and glutamate that resemble

168 rotein tyrosine phosphatase, PTPsigma, binds with high affinity to neural CSPGs.

169 FGF1 and FGF2 bind directly and with high affinity to NgR1 but not to NgR2 or NgR3.

170 rK1 appears to be a nitrate/proton symporter with high affinity for nitrate and NarK2 a nitrate/nitri

171 We show that both ATL proteins bind with high affinity to oligodeoxyribonucleotides containi

172 Initially, an FA binds with high affinity to one COX site of an unoccupied homo

173 own that these molecules preferentially bind with high affinity to one of the two G-quadruplex sequen

174 Proneurotrophins bind with high affinity to p75 neurotrophin receptor (p75NTR)

175 The papillomavirus E2 proteins bind with high affinity to palindromic DNA sequences consisti

176 Two aryloxyanilides with high affinity for PBR were identified and synthesiz

177 this pH-sensitive antibody is that it binds with high affinity to PCSK9 in the plasma at pH 7.4, whe

178 for a phospholipase-linked membrane protein with high affinity for PEDF, suggesting a molecular path

179 Finally Acam binds with high affinity to peptide versions of both myosin VI

180 ed cell death and is a lipid-binding protein with high affinity for phosphatidic acid (PA) and cardio

181 A minority of PX domains bind with high affinity to phosphatidylinositol 3-phosphate [

182 full-length rat Myo1b binds specifically and with high affinity to phosphatidylinositol 4,5-bisphosph

183 ABH binds with high affinity to phosphatidylinositol-3-phosphate (

184 Annexin V is a 36-kDa protein that binds with high affinity to phosphatidylserine lipids in the c

185 expression of alpha-haemolysin, a sae target with high affinity for phosphorylated SaeR, was not, dem

186 helix family of transcription factors, binds with high affinity to polycyclic aromatic hydrocarbons (

187 tein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protect it from degradation and pr

188 -labeled small-molecule PSMA inhibitors bind with high affinity to PSMA-positive tumor cells in vitro

189 protein (CspB) from Bacillus subtilis binds with high affinity to pyrimidine-rich sequences, with a

190 [3H]BNZA binds with high affinity to rat brain synaptosomal membranes (

191 Pralatrexate is a novel antifolate with high affinity for reduced folate carrier-1.

192 es an alternate receptor, CXCR7, which binds with high affinity to SDF-1 and to a second chemokine, i

193 we identified a 110 kDa protein, which binds with high affinity to SECIS elements from a subset of se

194 ion, T cells bearing T cell receptors (TCRs) with high affinity for self-antigen are eliminated.

195 ncounter a ligand, and gammadelta thymocytes with high affinity for self-ligand are CCR9(low).

196 a region of RBM25 spanning Lys-77 that binds with high affinity to serine- and arginine-rich splicing

197 o exhibits considerable promiscuity, binding with high affinity to several other fluorogenic cyanine

198 We report that CHD6 and CHD7 both bind with high affinity to short linker DNA, whereas CHD8 req

199 osophila Smad proteins, Mad and Medea, binds with high affinity to silencer elements that repress bri

200 se activity was also observed, and RPA bound with high affinity to single-stranded DNA containing a s

201 Here we show that Cas9 binds with high affinity to single-stranded RNA (ssRNA) target

202 shift assays indicated that BpaB also binds with high affinity to sites located in the 5' noncoding

203 nance equilibrium binding studies, APC bound with high affinity to soluble (s) ApoER2 (apparent K(d),

204 estigational PET/CT imaging agent that binds with high affinity to somatostatin receptor subtype 2, f

205 finding that neither SIGNR1 nor SIGNR5 binds with high affinity to specific ligands in a large panel

206 is a structure-specific DNA binding protein with high affinity for splayed arm and 3'-flap DNAs.

207 stranded (ss)DNA binding (SSB) proteins bind with high affinity to ssDNA generated during DNA replica

208 a number of allosteric states, the T state, with high affinity for substrate proteins, the ATP-bound

209 available in only one allosteric state, that with high affinity for substrate.

210 s) interfere with synaptic function and bind with high affinity to synapses, but the mechanism underl

211 Both AbetaOs and ADDLs bind rapidly and with high affinity to synaptic contacts and cellular mem

212 nous substrates showed that GPVI dimers bind with high affinity to tandem GPO (Gly-Pro-Hyp) sequences

213 ,3-b:4,5-c']dipyridine 9 ([(18)F]RO6958948)) with high affinity for tau neurofibrillary tangles, exce

214 e Pot1 protein, which binds specifically and with high affinity to telomeric ssDNA.

215 to bind to monomeric SNARE proteins but bind with high affinity to ternary SNARE complexes and with l

216 se competing ribosomes are known to be bound with high affinity to tetramers of the Sec61 complex.

217 However, TbetaRII-ED does bind with high affinity to TGFbeta2-TM, a TGFbeta2 variant su

218 as developed as a novel selective mGluR5 NAM with high affinity for the 2-methyl-6-(phenylethynyl)-py

219 al pyrrolizidine derivatives were identified with high affinity for the 5-HT(4) receptor, including b

220 type ( K i < or = 0.5-15 nM), a subset bound with high affinity for the alpha7 receptor subtype ( K i

221 sulted in acetyl-lysine mimic incorporation, with high affinity for the BRD4 bromodomain.

222 tor II, to create an active, chimeric enzyme with high affinity for the cation-independent mannose 6-

223 Several 3-acylindoles with high affinity for the CB(2) cannabinoid receptor an

224 ential, it is necessary to develop compounds with high affinity for the CB(2) receptor.

225 For instance, drugs with high affinity for the D2 receptor potently alter ti

226 discovery that a benztropine analog, JHW007, with high affinity for the DAT does not have cocaine-lik

227 he use of previously characterized compounds with high affinity for the four targets, and chemical ge

228 of displacing DEPTOR and activating mTORC1, with high affinity for the FRB domain of mTOR.

229 The peptide bombesin (BBN) is a peptide with high affinity for the gastrin-releasing peptide rec

230 ctions include an MHC class I homolog (UL18) with high affinity for the leukocyte inhibitory receptor

231 Ocaliva, a synthetic bile acid analog with high affinity for the nuclear bile acid receptor FX

232 We used L822429, a specific antagonist with high affinity for the rat NK1R, and examined whethe

233 sly developed a series of chemical compounds with high affinity for the sigma-2 receptor and showed r

234 Proteins with high affinity for the structure at chromosome ends,

235 mide derivative, a carbonic anhydrase ligand with high affinity for the tumor-associated isoform IX (

236 at the hantavirus nucleocapsid protein binds with high affinity to the 5' cap of cellular mRNAs, prot

237 s MHC class I-like protein (OMCP) that binds with high affinity to the activating receptor NKG2D on N

238 tro studies have shown that pregabalin binds with high affinity to the alpha(2)-delta (alpha(2)-delta

239 It binds with high affinity to the alpha(2)-delta subunit of volt

240 Cytisine, a partial agonist that binds with high affinity to the alpha(4)beta(2) nicotinic acet

241 mal and sickle red blood cells (RBCs) adhere with high affinity to the alpha5 chain of laminin (LAMA5

242 CP binds with high affinity to the barbed end of actin filaments,

243 45, a small molecule that specifically binds with high affinity to the BH3-binding groove of MCL1.

244 gamma-beta, the accessory subunit that binds with high affinity to the catalytic core, pol gamma-alph

245 lly disordered protein in solution but binds with high affinity to the catalytic dimer to reconstitut

246 By binding with high affinity to the CBS domains, AMP and ADP usual

247 V-1 envelope glycoprotein gp120, which binds with high affinity to the CD4 receptor.

248 Fiber binds with high affinity to the cell surface coxsackievirus-an

249 type member of the ANR family in EAEC, binds with high affinity to the central linker domain of AraC-

250 hoprotein that, when unphosphorylated, binds with high affinity to the complex of betagamma-subunits

251 Here we discovered that GAPDH binds with high affinity to the core ARE from tumor necrosis f

252 A variety of FAs can bind with high affinity to the COX site of the monomer that b

253 converting heteronuclear RNA to mRNA, binds with high affinity to the CSR1 C terminus.

254 s an analog of cocaine that binds reversibly with high affinity to the dopamine transporter (DaT) pro

255 ain within the E3 gp78 binds selectively and with high affinity to the E2 Ube2g2.

256 ead paralog, designated prozyme, which binds with high affinity to the enzyme and increases its activ

257 The 2,3-diarylindenes bind with high affinity to the ER subtypes and demonstrate a

258 at a novel miniature protein, pGolemi, binds with high affinity to the EVH1 domain of Mena (Mena1-112

259 ydrophobic and carboxylate groups that binds with high affinity to the Fc fragment of IgG.

260 y for designing a short-chain peptide ligand with high affinity to the Fc region of an antibody was p

261 mately 30 nt long the nuclease Dna2 can bind with high affinity to the flap and downstream double str

262 -mTFD-MPPB binds in the transmembrane domain with high affinity to the gamma(+)-beta(-) subunit inter

263 a 14-amino-acid amphibian peptide that binds with high affinity to the gastrin-releasing peptide rece

264 We found that NgR1 and NgR3 bind with high affinity to the glycosaminoglycan moiety of pr

265 (18)F-GP1 binds specifically with high affinity to the GPIIb/IIIa receptor involved i

266 mber of very well defined molecular cavities with high affinity to the HSA molecules.

267 Interleukin-2 (IL2) binds with high affinity to the IL2 receptors overexpressed on

268 Insulin binds with high affinity to the insulin receptor (IR) and with

269 We show that TamR binds with high affinity to the intergenic region between the

270 Our results show that p53 bound with high affinity to the junction of stalled forks, whe

271 In this study, we determined that HBZ binds with high affinity to the KIX domain of p300/CBP.

272 One peptide (termed compound 3), bound with high affinity to the Kunitz-1 (K1) domain of TFPI (

273 These showed that the amine bound with high affinity to the LC and to other selected brain

274 Glycopeptide dendrimers with high affinity to the lectins were identified by scr

275 103) and show that its protein product binds with high affinity to the Mc1r and has a simple and stro

276 AgRP binds with high affinity to the melanocortin 3 receptor and th

277 Both peptides bind with high affinity to the melanocortin-4 receptor (MC4R)

278 o determine that CsrA binds specifically and with high affinity to the moaA 5' mRNA leader.

279 N binds with high affinity to the mRNA cap replacing eIF4E.

280 sordered PrP(C) N-terminal tail, which binds with high affinity to the NCAM fibronectin type-3 domain

281 However, recombinant PPR53 did not bind with high affinity to the ndhA 5' untranslated region, s

282 rts its proinflammatory functions by binding with high affinity to the neurokinin 1 receptor (NK1R).

283 Amorfrutins are a family of natural products with high affinity to the peroxisome proliferator-activa

284 p53 bound with high affinity to the recognition elements of all th

285 ammaS-bound alpha(T) subunit is able to bind with high affinity to the recombinant, purified gamma su

286 that the histidine is essential for binding with high affinity to the ribosome.

287 Gp130-RAPS was shown to bind with high affinity to the stable IL-6/sIL-6R complex, hy

288 emonstrate that a novel inhibitor that binds with high affinity to the STAT3 SH2 domain triggers a co

289 KSRP binds with high affinity to the terminal loop of the target mi

290 monstrate that the ADP product remains bound with high affinity to the transition state complex but d

291 n3a-HDAC1 histone deacetylase complex, binds with high affinity to the trimethylated species.

292 We previously reported that NC binds with high-affinity to the repeating sequence d(TG)n.

293 IgE antibodies with high affinity for their antigens can be stably cros

294 at the cellular prion protein, PrP(C), binds with high affinity to these oligomers, acting as a putat

295 DNA sequences with high affinity for transcription factors occur more

296 At low and high concentrations, FDDNP binds with high affinity to two sites in the Abeta(10-40) mono

297 demonstrate that AlgR but not AlgRD54N bound with high affinity to two sites upstream of the fimU-pil

298 otropin-releasing factor (CRF) family, binds with high affinity to type 2 CRF receptors (CRFR2) on ca

299 ng proteins (GNAT1, NPHP3, and Cystin1) bind with high affinity to Unc119 proteins, whereas a peptide

300 aldol reactions of more demanding substrates with high affinity to water (i.e., acetone and formaldeh