ライフサイエンスコーパス: with high specificity

1 of protein complexes whose subunits interact with high specificity.

2 iple corresponding novel spatial experiences with high specificity.

3 is STR to bind to an unknown nuclear protein with high specificity.

4 adults using point-of-care ultrasonography, with high specificity.

5 rtunities for generation of neuroprotectants with high specificity.

6 ts could detect as low as 5 fg of target DNA with high specificity.

7 ism for forming protein dimers and oligomers with high specificity.

8 The sensor responds with high specificity.

9 lin imaging compound), which binds to myelin with high specificity.

10 number of Alu and non-Alu RNA editing sites with high specificity.

11 ck-out proteins within the secretory pathway with high specificity.

12 de-activated sugar to the macrolide scaffold with high specificity.

13 plex cellular conditions in individual cells with high specificity.

14 ften difficult for small molecules to target with high specificity.

15 mone (3R,7S)-jasmonoyl-l-isoleucine (JA-Ile) with high specificity.

16 e-fused recombinant proteins in living cells with high specificity.

17 recognize and incorporate correct substrates with high specificity.

18 otein-RNA interactions to organize complexes with high specificity.

19 he approach enabled rapid thrombin detection with high specificity.

20 in obtaining a larger number of fingerprints with high specificity.

21 FNs can be designed to target a chosen locus with high specificity.

22 endomysial antibodies tests were associated with high specificity.

23 This probe photolabels PfCRT in situ with high specificity.

24 hallenging to build target prediction models with high specificity.

25 addition to that of numerous other proteases with high specificity.

26 ce data may identify patients at risk for HT with high specificity.

27 a-2 receptor (18 kDa) in rat liver membranes with high specificity.

28 acterization of analytes in complex mixtures with high specificity.

29 ty as well as mismatches along their lengths with high specificity.

30 mor vasculature or extravascular compartment with high specificity.

31 of diverse biochemical changes in organisms with high specificity.

32 tion technique must combine high sensitivity with high specificity.

33 idly inhibits the GTPase activity of dynamin with high specificity.

34 ts show that hUG binds Lip-1R on these cells with high specificity.

35 GT must recognize its heterocyclic substrate with high specificity.

36 ium intercalators target DNA base mismatches with high specificity.

37 only three of these 11 bases are recognized with high specificity.

38 opulations and can assign fragments >or=1 kb with high specificity.

39 egative test can exclude metastatic deposits with high specificity.

40 HCCH peptide, is capable of binding to zinc with high specificity.

41 We selected an RNA aptamer that binds to HSF with high specificity.

42 , as they can recognize target DNA sequences with high specificity.

43 ung adenocarcinomas from normal lung tissues with high specificity.

44 DNA sequences at the cepI and aidA promoters with high specificity.

45 al-time detection of RNA secondary structure with high specificity.

46 recognize unique 18-base pair DNA sequences with high specificity.

47 nation, hyperdiploid myeloma can be detected with high specificity.

48 ed to analyze IgE in the low-nanomolar range with high specificity.

49 ected in 16 of 17 patients (94% sensitivity) with high specificity.

50 cts the success of electrical defibrillation with high specificity.

51 l fatty tissue can show perivesical invasion with high specificity.

52 deoxynucleotides instead of ribonucleotides with high specificity.

53 oducts, and RNA transcripts are all detected with high specificity.

54 simultaneously detect their cognate analytes with high specificity.

55 and CSBPB, and binds the consensus sequence with high specificity.

56 -Barr virus infected B-cells for destruction with high specificity.

57 1C]ABP688, which binds to an allosteric site with high specificity.

58 , individual receptor-ligand pairs associate with high specificity.

59 in vitro and the wild-type 3' sequence binds with high specificity.

60 demonstrate subpicomolar limit of detection with high specificity.

61 dephosphorylate ~15000 different substrates with high specificity.

62 h is a rapid isothermal amplification method with high specificity.

63 hich exhibits excellent DNA binding affinity with high specificity.

64 xpression on B cells captured seroconversion with high specificity.

65 xpressing high levels of novel genetic tools with high specificity.

66 binding pocket and that FES binds to ERalpha with high specificity.

67 lls/serum while binding to cells of interest with high specificity.

68 sters, sulfate esters, and carboxylic acids, with high specificity.

69 ase spatiotemporally at the site of interest with high specificity.

70 ctosidase genes into endogenous genomic loci with high specificity.

71 sport the ammonium and methylammonium cation with high specificity.

72 kewise can be targeted to uncover inhibitors with high specificity.

73 dentify RNA editing events from RNA-Seq data with high specificity.

74 ed in and eliminated bladder TCC efficiently with high specificity (10,000:1) in comparison with nonb

75 itors in the test group (20% of the dataset) with high specificity (86%) and sensitivity (78%).

76 redictive biomarker of in vivo drug response with high specificity (92%) and strong positive predicti

77 0, respectively; P = 0.000003 to < 0.000001) with high specificity (99 to 87%).

78 This process modifies with high specificity a conserved Pro, shares with the d

79 Incorporation of dye into UA crystals occurs with high specificity, affecting primarily [001] and [20

80 RNA elements must bind an effector molecule with high specificity against a background of other cell

81 -positive patients at risk for liver disease with high specificity, albeit with only moderate sensiti

82 ng protein kinases, designing drug compounds with high specificity among the kinases has proven diffi

83 tertiary structures to bind target molecules with high specificities and affinities.

84 The H3R and H4R activated Galphai with high specificity and a high potency.

85 eic acid aptamers can bind to target ligands with high specificity and affinity and may offer therape

86 trimethylated lysine residues of histone H3 with high specificity and affinity and no lot-to-lot var

87 of eukaryotic transcription factors bind DNA with high specificity and affinity as homo- or heterodim

88 Lm PAB1 binds poly(A) with high specificity and affinity but fails to compleme

89 unodeficiency virus type 1 (HIV-1) integrase with high specificity and affinity but whose function in

90 ger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create

91 dular subunits: an aptamer domain that binds with high specificity and affinity to a target ligand an

92 we selected a human Fab, designated KYK-2.0, with high specificity and affinity to human NKG2D.

93 combinant protein, we show that Pet54p binds with high specificity and affinity to the aI5beta intron

94 lity shift assays showed that AtWRKY30 binds with high specificity and affinity to the WRKY consensus

95 odies (mAbs) are a major class of medicines, with high specificity and affinity towards targets spann

96 ng analysis, and can bind E-box DNA (CACGTG) with high specificity and affinity, as determined by flu

97 Eight nanobodies, recognizing BBMV with high specificity and affinity, were retrieved after

98 onal receptors capable of binding chaperones with high specificity and affinity.

99 nant tumor cells and tumor microenvironments with high specificity and affinity.

100 ons CLADE produced a new aptamer to thrombin with high specificity and affinity.

101 te receptor, yet only domain 11 binds IGF-II with high specificity and affinity.

102 ognize their multiple and diverse substrates with high specificity and affinity.

103 TFOs) bind in the major groove of duplex DNA with high specificity and affinity.

104 selected for their ability to bind proteins with high specificity and affinity.

105 nobody that target their respective antigens with high specificity and affinity.

106 um metalloinsertors that bind DNA mismatches with high specificity and are preferentially cytotoxic t

107 nts of DSB hotspots - they bind DSB hotspots with high specificity and are required for DSB formation

108 We have generated an antibody with high specificity and avidity for Neu5Gc.

109 The FYVE domain binds with high specificity and avidity to phosphatidylinosito

110 single apoferritin molecules in vitreous ice with high specificity and determines their orientation a

111 hytic renal mass 2 cm or greater in diameter with high specificity and diagnostic accuracy.

112 -2B RNAi eliminates neoblast gene expression with high specificity and discrimination from gene expre

113 s may provide opportunities to target tumors with high specificity and efficacy.

114 chniques to manipulate microbial communities with high specificity and efficacy.

115 Isl1-Lhx3 drives MN differentiation with high specificity and efficiency in the spinal cord

116 hey have the potential to catalyze reactions with high specificity and efficiency without the use of

117 netic particles through the host interaction with high specificity and efficiency.

118 iates targeted DNA integration in Drosophila with high specificity and efficiency.

119 the 3' end of the Escherichia coli glmS gene with high specificity and efficiency.

120 te the development of potent antiviral drugs with high specificity and efficiency.

121 on mechanism combines structural promiscuity with high specificity and enables discrimination between

122 baby hamster kidney cell extracts that bind with high specificity and high affinity to sequences wit

123 ase resolution for studying genome structure with high specificity and high genome coverage.

124 metalloinsertors bind to DNA base mismatches with high specificity and inhibit cellular proliferation

125 Consolidation thus operates during sleep with high specificity and is subject to systematic influ

126 epressive Disorder, our method discriminated with high specificity and nearly perfect sensitivity the

127 engineered to detect diverse target proteins with high specificity and offer an attractive alternativ

128 a novel and viable way to detect biomarkers with high specificity and open the route to an original

129 The vacuolar H+-ATPase is inhibited with high specificity and potency by bafilomycin and con

130 imals have been identified that target ASICs with high specificity and potency.

131 zation of these goals will require reactions with high specificity and precise control.

132 polar disorder patients and control subjects with high specificity and predictive value compared with

133 Swi2/Snf2 protein, binds HJ-like structures with high specificity and promotes their bidirectional b

134 (1) ASL binding occurs with high specificity and relatively high affinities at

135 detection of relatively low abundance miRNAs with high specificity and reproducibility.

136 rategy to study the surfaces of living cells with high specificity and resolution down to 10-20 nm.

137 due to the fact that it combines sensitivity with high specificity and selectivity.

138 UMOD, MMP-7, SERPING1, TIMP1) classified AR with high specificity and sensitivity (area under ROC cu

139 and vaccenic acid (18:1n-7) predicted an LFD with high specificity and sensitivity (ROC curves: 0.99)

140 We report that zebrafish ORA1 recognizes with high specificity and sensitivity 4-hydroxyphenylace

141 ore assay that is capable of resolving 5 hmC with high specificity and sensitivity and demonstrate it

142 s assay can be used to immunophenotype NLHPL with high specificity and sensitivity and rapidly purify

143 inosis (BV); this subtype could be predicted with high specificity and sensitivity based on the Nugen

144 ntaminant nuts which could then be monitored with high specificity and sensitivity by selective react

145 were able to construct transcription modules with high specificity and sensitivity for many transcrip

146 Detecting target analytes with high specificity and sensitivity in any fluid is of

147 m the resulting catalog of TCRbeta sequences with high specificity and sensitivity in both the origin

148 The CRM genes could diagnose AR with high specificity and sensitivity in three additiona

149 Detection of SNPs with high specificity and sensitivity is essential for e

150 The lack of high-throughput methods with high specificity and sensitivity to detect changes

151 Four of the criteria performed well with high specificity and sensitivity whereas the other

152 vely diagnose acute cellular rejection (ACR) with high specificity and sensitivity would significantl

153 , rho L, between two LOD score profiles can, with high specificity and sensitivity, identify pairs of

154 This assay can detect and quantify HIV-1 RNA with high specificity and sensitivity.

155 y the size, content and location of variants with high specificity and sensitivity.

156 y in silico, bound the minimal FLAG sequence with high specificity and sensitivity.

157 e detection of resectable pancreatic cancer, with high specificity and sensitivity.

158 in vivo investigation of biochemical changes with high specificity and sensitivity.

159 ent dyes can image hydrogen peroxide in vivo with high specificity and sensitivity.

160 relate with melanoma metastasis to the liver with high specificity and sensitivity.

161 aortic PWV, and aortic bifurcation diameter with high specificity and sensitivity.

162 ing and diagnosis of syphilis require assays with high specificity and sensitivity.

163 l function in photoreceptor cells is derived with high specificity and sensitivity.

164 alysis and validation resulted in a gold set with high specificity and sensitivity.

165 ins, i.e., human serum albumin and lysozyme, with high specificity and sensitivity.

166 multiplexed and quantitative miRNA analysis with high specificity and sensitivity.

167 ed nodes may identify the seizure onset zone with high specificity and sensitivity.

168 of genes in tens of thousands of individuals with high specificity and sensitivity.

169 peptides bind to their cognate boxB targets with high specificity and show equal affinities for thei

170 te lattice within the tumor microenvironment with high specificity and soft-tissue contrast-to-backgr

171 uires the manipulation of cellular processes with high specificity and spatio-temporal precision.

172 GABA, dubbed GABA-Snifit, which senses GABA with high specificity and spatiotemporal resolution on t

173 ing, males respond to female-produced blends with high specificity and temporal resolution.

174 inhibit cytosolic sulfotransferases (SULTs) with high specificity and therapeutically relevant affin

175 These agents target cartilage with high specificity and this property is inherent to t

176 e that the BMP1 prodomain binds BMPs 2 and 4 with high specificity and with a KD of approximately 11

177 The final scaffolds bound b12 with high specificity and with affinity similar to that

178 e capable of detecting insulin and C-peptide with high specificity and with picomolar concentration d

179 Recombinant Sap1p bound Ter1 with high specificity, and endogenous Ter1 binding activ

180 UAAs are incorporated with high specificity, and functionally active transport

181 system detects single nucleotide mismatches with high specificity, and has a limit of detection of 1

182 ed, individual DNA cleavage events, rapidly, with high specificity, and in real-time are described.

183 c domains recombine user-defined DNA targets with high specificity, and that designed ZFRs integrate

184 dopsis thaliana were analyzed simultaneously with high specificity, and the sensitivity of the method

185 gh-affinity ligands recognizing biomolecules with high specificity are crucial for drug discovery and

186 mutants, we show that toxins and antitoxins with high specificity are frequently connected in sequen

187 roteins from complex cell and tissue lysates with high specificity as confirmed by SDS-PAGE analysis

188 The DR-TGD2C protein bound PtdOH with high specificity, as demonstrated by membrane lipid

189 STAGE tag analysis to identify enriched loci with high specificity, as verified by quantitative ChIP.

190 BoNTs bind with high specificity at neuromuscular junctions and the

191 ied TLK1B phosphorylated histone H3 at S(10) with high specificity both in a mix of core histones and

192 Gemin5 binds with high specificity, both in vitro and in vivo, to seq

193 s simplex virus-1 (HSV) in corneal scrapings with high specificity but poorer sensitivity.Real time P

194 binds tightly to DNA to recognize promoters with high specificity but then releases these contacts d

195 We find these probes form bonds with DNA with high specificity but with varied stability in respo

196 to be capable of detecting single molecules with high specificity, but achieving single-molecule sen

197 scopy (a time consuming and costly technique with high specificity, but low sensitivity), clinical us

198 to express a chimeric antigen receptor (CAR) with high specificity, but moderate affinity, for CEA an

199 B and T lymphocytes recognize antigens with high specificity, but neither initiate immune respo

200 can be identified by HLA class II tetramers with high specificity, but unexpected low sensitivity.

201 TFs target their DNA-recognition sequences with high specificity by binding with resident times of

202 uble- and single-stranded regions are coated with high specificity by telomere end-binding proteins,

203 y phosphorylated at the plasma membrane, and with high specificity by the apically localized kinase L

204 without appendicitis and are distinguishable with high specificity by using a PSV greater than 10 cm/

205 essed in trans targets the cis-repressed RNA with high specificity, causing an alteration in the stem

206 at bind to a range of semiconductor surfaces with high specificity, depending on the crystallographic

207 ks of misfolding or misassembly are targeted with high specificity despite the lack of any sequence s

208 hat all complexes bind to the mismatch sites with high specificities; DNA binding affinities to oligo

209 tantly related species can detect constraint with high specificity due to the loss of conserved neutr

210 lass arrays with signal amplification by RCA with high specificity, femtomolar sensitivity, 3 log qua

211 In ATP, Nar71 displaces ssDNA, also with high specificity for 3' flap and flayed duplex DNA.

212 ), self-associates in the presence of Ca(2+) with high specificity for antiparallel chain orientation

213 y a remarkable decarboxylating monooxygenase with high specificity for arginine.

214 nit of the DDB heterodimeric protein complex with high specificity for binding to a variety of DNA he

215 thesis, and evaluation of fluorogenic probes with high specificity for BlaC, a biomarker expressed by

216 18-4a (NH(2)-WxEAAYQkFL-CONH(2)) [corrected] with high specificity for breast cancer cells and improv

217 ) or PD153035, synthetic anilinoquinazolines with high specificity for EGFR, resulted in significant

218 nes and discovered a series of nanoparticles with high specificity for endothelial cells, activated h

219 ctrodes for the rapid detection of pathogens with high specificity for live cells.

220 ovel targeted imaging and therapeutic agents with high specificity for metastatic colorectal tumors i

221 itor variant (Ile-Lys-Pro-Arg-/-Ser-Ile-Pro) with high specificity for NSP4.

222 The high potency of inhibition, coupled with high specificity for PA over other phospholipids, s

223 T-1032, a compound with high specificity for PDE5 over PDE6, had a similar

224 scribe an algorithm for choosing a probe set with high specificity for targeted genes under equilibri

225 rotein (RPA), but unlike RPA, Teb1 binds DNA with high specificity for telomeric repeats.

226 tin I-Ome-AG538, a tyrosine kinase inhibitor with high specificity for the IGF-IR.

227 eishmania expresses a single acyltransferase with high specificity for the precursor dihydroxyacetone

228 dies, alpha-dendrotoxin (alpha-DTX), a toxin with high specificity for these members of the Kv1 famil

229 s identify a class of G+U-rich RNA sequences with high specificity for this protein.

230 Using the first operating cut point with high specificity, for EyePACS-1, the sensitivity wa

231 are then captured by a thiol-affinity resin with high specificity (>97%).

232 phopeptide enrichment from a complex mixture with high specificity (>99%), which could almost be cons

233 EHI_182030 (10 pg/mL, corresponding 453 fM) with high specificity has been achieved, employing the n

234 ells upon chemical or mechanical stimulation with high specificity, high sensitivity and wide dynamic

235 of technologies to isolate these tumor cells with high specificity; however, there are limited techni

236 s regulate AMPAR trafficking and degradation with high specificity in response to differing neuronal

237 romoter drives transgene reporter expression with high specificity in small intestinal goblet cells o

238 RP-1 physically interacts with NF-kappaB-p50 with high specificity in the absence of betaNAD+.

239 system is quantitative, reversible and works with high specificity in vitro and in vivo in living bac

240 th single- and double-stranded telomeric DNA with high specificity in vitro.

241 cleaves a semi-palindromic 15-bp target site with high specificity in vivo and in vitro.

242 logues were shown to target carrier proteins with high specificity in vivo and undergo chemoselective

243 ogical probes that inactivate individual SHs with high specificity in vivo.

244 romophores having a metalloporphyrin moiety, with high specificity into the interior core of the bund

245 The HA complex recognizes E-cadherin with high specificity involving extensive intermolecular

246 thin the right upper quadrant of the abdomen with high specificity, irrespective of gestational age.

247 ment of ultrasensitive analytical techniques with high specificities is required to analyze the cell

248 many small molecules in a single measurement with high specificity is a significant improvement over

249 a single aaRS binds distinct anticodon loops with high specificity is not well understood.

250 cPMP by MoaC or its human homologue, MOCS1B, with high specificities (Km < 0.060 muM and 0.79 +/- 0.2

251 This method recovers with high specificity known microRNA target sites that h

252 single molecules in a living bacterial cell with high specificity, millisecond time resolution, and

253 ata suggest that CheR methyltransferases act with high specificity on their cognate chemoreceptors.

254 suggesting that after replication a nuclease with high specificity or constrained action acts on the

255 se (GST, glutathione S-transferase) isoforms with high specificity or high promiscuity are compared.

256 led descriptors and can be used to identify, with high specificity, other similar motifs within the n

257 achieved was 95-99% across alteration types, with high specificity (positive predictive value >99%).

258 ble in the absence of added RNA and binds U8 with high specificity, requiring the conserved octamer s

259 zable technique to image endogenous proteins with high specificity, resolution, and contrast in singl

260 of the degree of processing it has undergone with high specificity, sensitivity and rapidity.

261 inct from Mk exosomes (MkExos), target HSPCs with high specificity since they have no effect on other

262 These enzymes are being engineered with high specificity such that off-target binding of ce

263 and their ability to bind long DNA sequences with high specificity, TALEs have been used in many appl

264 ells, we demonstrate labeling of fixed cells with high specificity that correlates well with fluoresc

265 These aptamers recognize with high specificity the isoalloxazine nucleus of FAD b

266 Furthermore, we demonstrate with high specificity the same multiplexed detection usi

267 Human cytochrome P450 aromatase catalyzes with high specificity the synthesis of estrogens from an

268 ce methyltransferase DNMT1, which methylates with high specificity the unmethylated strand of a hemim

269 ormally selects the genomic RNA of the virus with high specificity; the nucleocapsid (NC) domain of G

270 The DDB1-DDB2 complex also bound with high specificity to a UV radiation-induced (6-4) ph

271 al abnormal vision-like (ELAV) protein binds with high specificity to at least two AU-rich elements w

272 lation of B2.1, a dimeric peptide that binds with high specificity to b12 and competes with gp120 for

273 We show that although F3-Cis-Np bind with high specificity to both human ovarian tumor cells

274 In patients, mAb A33 localizes with high specificity to colon cancer and is retained fo

275 This complex binds with high specificity to DNA damaged by UV, is absent in

276 b domains accounts for IgG's ability to bind with high specificity to essentially any antigen.

277 ndonucleases (HEs) cut long DNA target sites with high specificity to initiate and target the lateral

278 is a calcium-independent lectin, which binds with high specificity to O-linked alpha1,4-GlcNAc-capped

279 The FYVE finger domain binds with high specificity to PtdIns3P and proteins containin

280 ycling sequence binding protein (CSBP) binds with high specificity to sequence elements in several mR

281 UV-vis) of the protein showed that it bound with high specificity to the desired cofactors, suggesti

282 ineered zinc finger protein (Gq1) that binds with high specificity to the intramolecular G-quadruplex

283 interaction assays revealed that c-Jun binds with high specificity to the largest subunit of human TF

284 PLCgamma1-SH3 bound with high specificity to the SLP-76 motif 186PPVPPQRP193

285 We are identifying proteins that bind U8 RNA with high specificity to understand how U8 functions in

286 ted into isolated chloroplasts and interacts with high specificity to uridine-rich regions within the

287 TZF homologs tristetraprolin and ERF-2 bind with high specificity to UUAUUUAUU elements.

288 unctionalities in the side chains that react with high specificity toward thiol ligands.

289 n be used as a tool to monitor and quantify, with high specificity, tumor response in PSMA-positive p

290 cilitates the detection of peritoneal tumors with high specificity upon intraperitoneal tumor targeti

291 the TTP family of proteins, TIS11d binds RNA with high specificity using a pair of CCCH-type tandem z

292 homogeneous solution at ambient temperatures with high specificity using a sophisticated biosensor.

293 yltransferase activity in Enterobacteriaceae with high specificity using the standard disk susceptibi

294 structural protein 3 (NS3):1406-1415 epitope with high specificity when presented by HLA-A2.

295 tion, binding occurs in the RNA major groove with high specificity, whereas binding to the all-DNA an

296 etween CEA protein and anti-CEA in real-time with high specificity, which revealed selective electric

297 mers were shown to detect various quinolones with high specificity, while specific binding activities

298 inine 12 and lysine 24 interact strongly and with high specificity with the phosphate group of the DP

299 e to detect intracellular cancer RNA markers with high specificity within 30 minutes post treatment,

300 r phosphatases dephosphorylate their targets with high specificity, yet the structural and sequence d