ライフサイエンスコーパス: without compromising

1 all nucleotides in 3196 transcripts of yeast without compromising accuracy, while the simple threshol

2 res, aiming to improve solubility and safety without compromising activity against VL.

3 ied regions of 1 that tolerate modifications without compromising activity and afforded the discovery

4 e 3'-position to tolerate large substituents without compromising activity, whereas bulk and rigid su

5 control allows an animal to adjust its path without compromising additional roles for the zigzag pat

6 pportunities for inhibiting immune pathology without compromising Ag-specific immunity in vivo.

7 rd MC4R over MC3R and MC5R receptor subtypes without compromising agonist potency.

8 sed to enhance the selectivity of the method without compromising analysis speed.

9 antibody persistence through early childhood without compromising antibody responses in early infancy

10 xpected to block autoimmune T cell responses without compromising antiviral immunity.

11 that SimRA produces the ARG in compact forms without compromising any accuracy.

12 issues and serially collected urine samples, without compromising auditory and kidney functions.

13 which inhibits the ER Ca(2+) ATPase activity without compromising barrier integrity, also leads to de

14 present relevant features of the environment without compromising behavior.

15 8 could be improved through rational design, without compromising breadth and potency.

16 maintain a high syntaxin-1 expression level without compromising Ca(2+) influx, and recruitment of s

17 VEGF-B increased left ventricular volume without compromising cardiac function, reduced the expre

18 may be a target for decreasing expenditure, without compromising care.

19 igher number of turnovers compared with APX2 without compromising catalytic efficiency.

20 W), and lowered ICA and MCA Vmean by 12-23% without compromising CCA blood flow.

21 e may be beneficial by reducing inflammation without compromising CD8 CTL.

22 Notably, CMTM6 depletion decreases PD-L1 without compromising cell surface expression of MHC clas

23 own reduced migration, inhibited cell growth without compromising cell survival, and suppressed tube

24 g payload capacity with prior DNA incubation without compromising cell viability.

25 icking of dilysine-containing cargo in yeast without compromising cell viability.

26 cle inflammation in a dose-dependent manner, without compromising cellular and humoral immunity.

27 ufficiently tailor their magnetic properties without compromising cellular biocompatibility.

28 ty, identifies residues amenable to mutation without compromising cellulose affinity, and informs eng

29 uptive effects of nocturnal light in humans, without compromising chromaticity.

30 ods for labeling a tunable fraction of cells without compromising color diversity.

31 o[1,2-a]pyridine ring, which can be modified without compromising compounds' potency.

32 ontrolled drug delivery at therapeutic rates without compromising critical lens properties.

33 e readily processed for microfluidic sorting without compromising CTC yield and viability.

34 uated over the port, can remove these chains without compromising degradation because substrates must

35 ptive statistical iterative reconstruction , without compromising depiction of findings or image qual

36 n more accurately in noisy visual conditions without compromising directional tuning.

37 ising method to minimize byproduct formation without compromising disinfection and nutrient removal.

38 significantly improves the sparing of BS/SC without compromising dosimetric requirements of other in

39 that result in truly universal hybridization without compromising duplex thermostability has proven c

40 ymmetric and non-symmetric BINOL derivatives without compromising e.r.

41 proliferation and myotube formation improved without compromising each other, which indicates the myo

42 empt to decrease treatment-related morbidity without compromising efficacy.

43 nhibitor, could replace oral glucocorticoids without compromising efficacy.

44 ity in a bid to diminish off-target toxicity without compromising efficacy.

45 r kidney function than standard TAC (TAC-C), without compromising efficacy.

46 am of glucocorticoids that minimize toxicity without compromising efficacy.

47 r the reverse sequence, could improve safety without compromising efficacy.

48 d cost-efficient hole-transporting materials without compromising efficiency, stability, or scalabili

49 Increasing DA sensitivity without compromising electrode kinetics is expected to s

50 ns facilitate hydration and ion penetration, without compromising electronic mobility, and suggest th

51 al obstacle of achieving structural rigidity without compromising environmental interaction.

52 upports, reduction of the staircasing effect without compromising fabrication time, and isotropic mec

53 ARST0331 was to reduce the length of therapy without compromising FFS for this subset of low-risk pat

54 ament twisting enhances cofilin dissociation without compromising filament integrity.

55 the major clades confers clinical resistance without compromising fitness and transmissibility, showi

56 oper responsiveness to environmental stimuli without compromising fitness of the organism.

57 end portfolios cost effectively, potentially without compromising fuel quality or emissions reduction

58 narios which facilitate ecosystem protection without compromising future generations.

59 ices that can meet the immediate food demand without compromising future water resources seem critica

60 n enhance the encoding of nose-up sensations without compromising gaze stabilization.

61 regenerative capacity in maturing organisms without compromising gene functions regulated by develop

62 includes bio-LDPE provides added flexibility without compromising GHG targets.

63 crops and could be used for fuel production without compromising global food security.

64 ons are achieving better refractive outcomes without compromising graft clarity in combined endotheli

65 voids potential complications of steroid use without compromising graft survival, even after accounti

66 f biofuel-relevant lipids in these organisms without compromising growth is an important aspect of ad

67 r substituents on plant wall polysaccharides without compromising growth or viability.

68 stained accumulation of lipid droplets (LDs) without compromising growth, which results in much highe

69 lipid accumulation in eukaryotic microalgae without compromising growth.

70 upplement, increased D. piger and H2S levels without compromising gut barrier integrity.

71 arrier dysfunction in pneumococcal pneumonia without compromising host defence.

72 ctively promote resolution and tissue repair without compromising host defense.

73 become tolerant to a high bacterial burden, without compromising host fitness.

74 front line of antiviral defense in the lung without compromising host fitness.

75 umor initiation and impair tumor progression without compromising IL-6 classic signaling-driven prote

76 or CT angiography of the peripheral arteries without compromising image quality and diagnostic perfor

77 providing diagnostically acceptable CT scans without compromising image quality and in the detection

78 feasible using a hybrid CZT SPECT/CT camera without compromising image quality or significantly alte

79 to determine the maximal reduction possible without compromising image quality or the quantification

80 n provide diagnostically acceptable CT scans without compromising image quality.

81 therapies that target inflammatory responses without compromising immune defense.

82 g immunological tolerance to target antigens without compromising immune function.

83 t effect and how best to disseminate the TDP without compromising implementation fidelity.

84 e start codon of the A19L open reading frame without compromising infectivity.

85 involves the reduction of sample complexity without compromising information content.

86 x and helix-(pi-sheet)-coil assemblies occur without compromising intrinsic helicity, while both para

87 t in 3 min and was reused at least 100 times without compromising its accuracy.

88 gree of modifications the sgRNA can tolerate without compromising its association with SpCas9 and fun

89 of n-type Bi2Te3 in an extraordinary manner without compromising its basal plane properties.

90 a destabilization of gelsolin second domain, without compromising its calcium binding capacity.

91 ic order into a topological insulator system without compromising its distinctive quantum coherent fe

92 alkylation of two surface-exposed cysteines without compromising its DNA binding activity.

93 tern, a bacterium can reduce its diffusivity without compromising its drift in the chemical gradient.

94 e scope, including unactivated fluoroarenes, without compromising its efficiency and scalability, thu

95 y to prolong protein serum half-life in vivo without compromising its folded structure and activity.

96 luorophores can render a protein fluorescent without compromising its function.

97 be scaled up by a factor of 3,600 in volume without compromising its function.

98 l detection in artificial interstitial fluid without compromising its sensitivity, stability and resp

99 s enhance the kinase inhibitory potency of R without compromising its specificity.

100 ratrial shunt to decompress the left atrium (without compromising left ventricular filling or forward

101 ll sensitivity by enhancing phosphorylation, without compromising ligand discrimination.

102 ociated with improved perioperative outcomes without compromising long-term survival compared with bi

103 balance for improving transplant eligibility without compromising longer-term outcomes.

104 he potential exists to reduce radiation dose without compromising low-contrast detectability by using

105 troleum, yielding high recovery values (98%) without compromising maltene integrity.

106 b in lamb diet could increase PUFA in muscle without compromising meat oxidative stability.

107 R conferred resistance to both FIP and AS-48 without compromising membrane fusion.

108 t attenuating macrophage cytokine responses (without compromising microbicidal activity), thereby res

109 ata as an easy way to reduce false positives without compromising much sensitivity in intact glycopep

110 layed the onset of GVHD-associated mortality without compromising myeloid engraftment, demonstrating

111 o substitution, resulted in higher stability without compromising native monomer fold or function.

112 s were significantly less susceptible to RKN without compromising nematode penetration, suggesting a

113 hat can be targeted to regulate inflammation without compromising NK cell cytotoxicity.

114 rtially attenuated peripherally induced itch without compromising nociceptive processing.

115 ctive in vitro and in vivo expansion of HSCs without compromising normal hematopoiesis.

116 and autoimmune lymphoproliferative syndrome, without compromising normal immunity.

117 rapidly diffuse through multiple FG repeats without compromising NPC selectivity is not yet fully un

118 ds could lower the sodium content to 1500 mg without compromising nutrient adequacy.

119 s in electron microscopy with higher current without compromising on spatial resolution.

120 age devices that provide high specific power without compromising on specific energy are highly desir

121 ryote samples possible on a standard desktop without compromising on the accuracy of results.

122 r by using heterogeneous computing platforms without compromising on the quality of variants.

123 at demonstrates high genome-wide specificity without compromising on-target activity in human cells.

124 ssociated with favorable short-term outcomes without compromising oncologic results.

125 w to minimise the frequency of complications without compromising oncological or cosmetic outcomes of

126 lenging cases, improving functional outcomes without compromising OOKP success.

127 How to lower the junction resistance without compromising optical transmittance has become th

128 MS identification can be repeatedly analyzed without compromising organism identification.

129 implanted cells from autoimmune destruction without compromising other aspects of the immune system

130 ech is to study disorders that affect speech without compromising other cognitive or motor functions.

131 ities to improve PCI value by reducing costs without compromising outcomes.

132 offer the potential for larynx preservation without compromising overall survival.

133 ormation particularly with RNA as complement without compromising pairing selectivity.

134 reductions in costs, resource use, and waste without compromising patient care.

135 reducing the variation in total cost of PCI without compromising patient outcomes.

136 gorithm is needed to improve its specificity without compromising patient safety.

137 ssen the climate impact of surgical services without compromising patient safety.

138 ility criteria that prioritize inclusiveness without compromising patient safety.

139 owing hypoventilation may decrease hypoxemia without compromising patient tolerance.

140 d to reduce costs in terms of time and money without compromising patients outcome.

141 non-severe acute respiratory tract infection without compromising patients' recovery in primary healt

142 ed in an attempt to avoid visible neck scars without compromising patients' safety and the effectiven

143 ion at flow rates ranging from 1 to 5muL/min without compromising performance.

144 remains unclear how they operate efficiently without compromising periplasmic plasticity.

145 eans of reducing the cost of acid extrusion, without compromising pH homeostasis, would therefore be

146 ries of copper complex based redox mediators without compromising photocurrent densities.

147 e used to produce ADC with high drug loading without compromising physicochemical and pharmacokinetic

148 o engineer broad-spectrum disease resistance without compromising plant fitness in the laboratory or

149 Mesh fixation without sutures is feasible without compromising postoperative outcome.

150 to bind to a wide range of chaperone clients without compromising precise control of thermodynamics a

151 rtantly because it can increase adaptability without compromising precision of learning.

152 e a method for identifying genetic relatives without compromising privacy by taking advantage of nove

153 th quality oversight improves patient access without compromising procedural or 1-year outcomes.

154 its, it should be possible to select for DPR without compromising production.

155 llaborative model reduces time to graduation without compromising productivity or alumni outcomes.

156 es the evaluation of HAS disease progression without compromising prognosis of HE patients, thereby a

157 d-node radiotherapy (IN-RT) could be omitted without compromising progression-free survival in patien

158 ided endoderm and hepatocyte differentiation without compromising proliferation.

159 lammation (IL-6, CCL2, and CCL20 expression) without compromising prosurvival responses.

160 an be placed anywhere in open reading frames without compromising protein expression.

161 roteomics approaches into a unified platform without compromising protein identification and quantita

162 cal care cost-effectiveness and patient flow without compromising quality, but these potential benefi

163 opportunity to limit costs in vascular care without compromising quality.

164 untries, suggesting programs can be expanded without compromising quality.

165 esentation of ethologically relevant stimuli without compromising reflexive behavior.SIGNIFICANCE STA

166 tegies for crop protection against biotrophs without compromising resistance to necrotrophs.

167 lain how reduced shoot branching is achieved without compromising root growth, leading to the charact

168 y that enhances their access to these agents without compromising safety or development strategies.

169 ineered to maximize levels of immunogenicity without compromising safety.

170 do well receiving lower doses of concentrate without compromising safety.

171 gimen (VTDC) could further increase efficacy without compromising safety.

172 the risk of target vessel revascularization without compromising safety.

173 estigators derived apparent clinical benefit without compromising safety.

174 urrent VTE compared with standard treatment, without compromising safety.

175 al resections in epilepsy surgery procedures without compromising seizure control.

176 r conventional fluorescence-based techniques without compromising sensitivity or selectivity.

177 Mirnacle substantially improves selectivity without compromising sensitivity.

178 aneous measurement of blood borne biomarkers without compromising sensitivity.

179 s, and scan rates are up to 250 times faster without compromising sensitivity.

180 er of magnitude faster than existing systems without compromising sensitivity.

181 the specificity of clinical event detection without compromising sensitivity.

182 reduced cost, labour and assay heterogeneity without compromising sensitivity.

183 otentially identify additional usable organs without compromising short-term outcomes.

184 roduction, nor increase protein provisioning without compromising somatic cultivar growth.

185 of scans with uncorrelated speckle patterns without compromising spatial resolution.

186 MP increased detection of aggressive disease without compromising specificity in patients that were d

187 arged residues to increase antibody affinity without compromising specificity.

188 or school-based eye health programs in India without compromising spectacle wear, at least in the sho

189 hopeptide identification in complex samples, without compromising speed and sensitivity.

190 opportunities to improve patient experience without compromising speed or thoroughness.

191 with the flexibility to continuously remodel without compromising stability and function.

192 ducing shape, alloying or strain effects and without compromising stability.

193 gen-binding site that can tolerate diversity without compromising stability.

194 duce intermittent rivalry and rivalry memory without compromising static rivalry and other cortical p

195 se will reveal new therapeutic opportunities without compromising steady state functions.

196 lerated under the catalytic relay conditions without compromising stereoselectivity.

197 to allow individual cells to change position without compromising structural integrity are not well u

198 ystals under catalytic operating conditions, without compromising structural integrity of the catalys

199 le of the ssSPTs is to increase SPT activity without compromising substrate specificity.

200 currence to reduce the frequency of CT scans without compromising surveillance benefits.

201 e potential to reduce the frequency of scans without compromising surveillance benefits.

202 tumorigenesis following partial hepatectomy without compromising survival or liver mass recovery.

203 y enhances cardiac function and performance, without compromising survival.

204 hat minimize toxicity and access disparities without compromising survival.

205 c patients reduces subsequent nephrotoxicity without compromising survival.

206 roendocrine functional outcomes over 5 years without compromising survival.

207 es chronic graft-versus-host disease (cGVHD) without compromising survival.

208 ally accelerated and enhanced sarcomagenesis without compromising synovial sarcoma characteristics.

209 into disease-suppressing regulatory B cells, without compromising systemic immunity.

210 95% of signals detectable in shotgun spectra without compromising the accuracy and scope of lipid ide

211 detection process at relatively lower costs without compromising the accuracy of detection.

212 n a dose-dependent manner by 48% (p < 0.001) without compromising the anti-PD effect of levodopa or c

213 ed to improve the physicochemical properties without compromising the antimycobacterial activity.

214 ss with timed administration after cisplatin without compromising the antitumour efficacy of cisplati

215 s under mild conditions and can be scaled up without compromising the asymmetric induction.

216 ted enzyme via modulation of the working pH, without compromising the binding affinity of the alloste

217 und diminution of the brain microvasculature without compromising the blood-brain barrier.

218 ocols can often reduce total anesthesia time without compromising the clinical value of the study.

219 generation and spin modulation in 2D devices without compromising the delicate material structures.

220 clude a) ease of swallowing and b) divisible without compromising the drug release characteristics of

221 n from doxorubicin-associated cardiotoxicity without compromising the efficacy of anticancer treatmen

222 be accomplished in an ophthalmology practice without compromising the efficiency of or patient satisf

223 TGF-beta1 inhibits CFTR biogenesis without compromising the epithelial phenotype or integri

224 ory response of class III da sensory neurons without compromising the expression of the ion channel N

225 cytokinesis in the liver slows tumor growth without compromising the health of normal hepatocytes.

226 xes, we were able to obtain stable complexes without compromising the helical secondary structure as

227 primary melanoma for fresh tissue biobanking without compromising the histopathological evaluation.

228 uppressing unwanted humoral immune responses without compromising the host's ability to respond to fo

229 , which should alter the secondary structure without compromising the immunogenic properties of the m

230 ct against challenge with (homologous) virus without compromising the induction of robust cross-react

231 ay block the transition to aberrant polymers without compromising the inhibitory activity of Z alpha1

232 udies, to targeting only a single amino acid without compromising the intensity of the response and/o

233 M2 macrophages, and granulation tissue size without compromising the mechanical properties.

234 All of these benefits are derived without compromising the methacrylate conversion of the

235 oid heavy confluent treatment at these sites without compromising the need for adequate retinopexy.

236 via a novel carbon dioxide release mechanism without compromising the neutral surface charge required

237 ng the local gas dynamics in the sample area without compromising the overall analysis efficiency.

238 for highly sensitized transplant candidates without compromising the overall health benefits among t

239 ient delivery of VSV through the bloodstream without compromising the patient's immune system.

240 e (D)CDX peptides onto the surface of RBCNPs without compromising the peptide's brain targeting abili

241 microbial communities within them can evolve without compromising the performances of the bioreactors

242 ld promise as a strategy to combat renal IRI without compromising the protective innate immune respon

243 d a decrease in the consumption of resources without compromising the quality of ICD recipients' care

244 s can be stored for extended periods of time without compromising the quality of the final NPs.

245 um can be cultivated under saline conditions without compromising the quality of the final product, e

246 SAMs allowed tuning of reaction selectivity without compromising the rate of desired product formati

247 ent function, implying a large dynamic range without compromising the requirement to suppress transcr

248 ion of exon X-containing Cep290 transcripts, without compromising the retinal structure.

249 ssible to apply the microcapsules in yogurt, without compromising the rheological properties and phys

250 ed by a simpler, less rigid cyclohexane ring without compromising the S1P receptor affinity profile o

251 individual lipid species could be determined without compromising the scope, accuracy, and dynamic ra

252 84.2% in BAs and from 73.8% to 94.1% in WAs without compromising the sensitivity of the ECG in detec

253 UHPLC was investigated as quick alternative without compromising the separation, analysis time short

254 es which significantly increased sensitivity without compromising the specificity of the immunoassay.

255 126.6% energy beyond their theoretic limits without compromising the stability of the cell voltage.

256 ced thickness could be adopted up to 60days, without compromising the standard commercial life of ind

257 he depletion of ChIs markedly attenuated LID without compromising the therapeutic efficacy of L-DOPA.

258 xhibiting low haze (<1%) to high haze (~56%) without compromising the total forward transmittance (~9

259 to develop large-scale fabrication processes without compromising the trapping efficiency.

260 ry of reactive species to a downstream point without compromising the underpinning species generation

261 agnetic separation process requires scale-up without compromising the viability of the cells.

262 e, the plasma wave can be locally overloaded without compromising the witness bunch normalized emitta

263 their environmental endosymbiont relatives, without compromising their ability to obtain nucleotides

264 two or more DARPins in predefined geometries without compromising their binding affinities and specif

265 tically transparent samples within 1-2 weeks without compromising their cellular architecture or endo

266 es to be accomplished at a variety of levels without compromising their conformational integrity.

267 oups at high density in aliphatic polyesters without compromising their crystallinity via the copolym

268 ide and enabled expansion of CD7 CAR T cells without compromising their cytotoxic function.

269 labels matrix proteins with high resolution, without compromising their distribution or mechanical fu

270 se the Young's modulus of the bio-elastomers without compromising their elongation ability.

271 cesses be modified in response to challenges without compromising their essential functions?

272 pment of devices that can store more energy, without compromising their fast charging and discharging

273 to discover whether or not they are related without compromising their genetic information or reveal

274 ansition metal oxides with a tunable bandgap without compromising their intriguing physical propertie

275 using a swelling and freeze-drying procedure without compromising their mechanical properties.

276 ng in meat products, enabling salt reduction without compromising their microbial stability.

277 lexibility, and can sustain repeated folding without compromising their optical performance.

278 ificant decrease in strain in cyclic alkynes without compromising their reactivity in alkyne-azide cy

279 t in the nutraceutical potential of GF cakes without compromising their sensory quality.

280 the fundamental behavior of such cell lines without compromising their viability may provide an impo

281 rotein resulting in the HSA binding capacity without compromising therapeutic activities.

282 interval between injection and NIR exposure without compromising therapeutic effects of photoimmunot

283 r complementarity-determining regions (CDRs) without compromising thermodynamic stability is critical

284 utput from the spinal cord for several hours without compromising these functions with anesthesia.

285 ectrodes can result in increased sensitivity without compromising time response.

286 AV serotype 1 capsid template can evade NAbs without compromising titer, transduction efficiency, or

287 -product with increased bioactive properties without compromising total yield.

288 ed by activating an envelope stress response without compromising trafficking of essential lipoprotei

289 y infiltrating cytotoxic T lymphocytes (CTL) without compromising tumor burden.

290 capturing the beneficial effects in the CNS, without compromising tumor suppression.

291 -induced volume expansion and cardiac events without compromising TZD actions in metabolic switch in

292 diminished tumour vascularization and growth without compromising vascular homeostasis in other organ

293 ular disease to reduce VEGF165-induced edema without compromising vessel growth.

294 translation machinery that function together without compromising viability or clashing with endogeno

295 d reduced NOTCH2 expression in cGVHD B cells without compromising viability.

296 odel by which MxA achieves antiviral breadth without compromising viral specificity.

297 rates of death at both 24 weeks and 48 weeks without compromising viral suppression or increasing tox

298 egy for inserting motifs into the AAV capsid without compromising viral titer or infectivity.

299 new optimized regimen can safely omit NRTIs without compromising virologic efficacy.

300 inding can fine tune the basepair geometries without compromising with their stability.