ライフサイエンスコーパス: worm

1 Caenorhabditis elegans became known as 'the worm'.

2 species colloquially referred to as 'Bobbit worms'.

3 hole-Organ Magnetic Resonance Imaging Score (WORMS).

4 eople worldwide are infected with helminths (worms).

5 ding to as few as one or two cells in the L2 worm.

6 ng common to species as different as man and worm.

7 al microtubules (PLMs)] on both sides of the worm.

8 enerate within about a week, forming two new worms.

9 sicles are converted into weakly interacting worms.

10 d vesicles, prior to their administration to worms.

11 dr-1 and pink-1 mutants but not in wild-type worms.

12 al bacteria presented in normal and infected worms.

13 umans, and parasites ranging from viruses to worms.

14 ions decreases significantly in egfr-3(RNAi) worms.

15 ug screen as promoting increased lifespan in worms.

16 was partially abolished in vitamin C-treated worms.

17 ayi, as compared to non-heme-treated control worms.

18 composition between uninfected and infected worms.

19 may thus be attributed to lacking mmBCFAs in worms.

20 stigating the therapeutic potential of these worms.

21 andom curving of ZnO nanorods and forms nano-worms.

22 of oxidative stress, particularly in younger worms.

23 otype of both the arf-1.1 and the ncs-1 null worms.

24 the Ca(2+) transients), except in very young worms.

25 l long-lived mutants, including daf-2 mutant worms.

26 e aging, and elongates survival in flies and worms.

27 graphical ranges of diseases caused by these worms.

28 polychaetes, and about 80% in fish ingesting worms.

29 ausing defective vulval morphology in mutant worms.

30 eloped to analyze fluorescence expression in worms.

31 crayfish and ectosymbiotic branchiobdellidan worms.

32 af-2 worms compared with the soma of control worms.

33 antly reducing the burden of VRE in infected worms.

34 on Earth, outnumbering insects and nematode worms.

35 younger worms and survival effects in older worms.

36 certain conditions, e.g. from dauer or aging worms.

37 s in synaptic dysfunction in mice, flies and worms.

38 suppressor of tau toxicity in tau transgenic worms.

39 the radiolar eyes arose independently in fan worms.

40 olution in zebrafish, Drosophila larvae, and worms [6-10].

41 ost interactions, we studied the enchytraeid worm, a bulk soil feeder that thrives in Arctic peatland

42 In worms, a histone-modifying enzyme is necessary to keep s

43 an immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, can prevent pathology ass

44 onsible for the developmental defects in the worm and conceivably might also be a critical contributo

45 Comparing the worm and fly data sets, we found that these genes were h

46 ethod for excised single neurons from marine worm and squid, and then exterior to intact, optically o

47 585 TFs in five species (human, mouse, fly, worm and yeast).

48 We test ibuprofen-treated worms and a TRPV (transient receptor potential) mutant,

49 emarkable regeneration capacity of planarian worms and demonstrate the power of this automated method

50 oni induces antibodies to glycan antigens in worms and eggs, but the differential nature of the immun

51 testinal AAM presence while decreasing adult worms and fecal egg production when compared with infect

52 Effects of indoles on healthspan in worms and flies depend upon the aryl hydrocarbon recepto

53 lifespan in yeast and organismal lifespan in worms and flies.

54 ms and reduces amyloid aggregation in cells, worms and in transgenic mouse models of Alzheimer's dise

55 Animals from worms and insects to birds and mammals show distinct bod

56 Diverse animals ranging from worms and insects to birds and turtles perform impressiv

57 ch as the exertion of physical stress on the worms and limited throughput.

58 as a sensor for alpha-DCs, conserved between worms and mammals.

59 family that converts H4K20me2 to H4K20me1 in worms and mammals.

60 ontrolling neuronal regeneration capacity in worms and mice.

61 ol human morbidity attributable to parasitic worms and progress toward elimination.

62 increases the fitness and lifespan of GMC101 worms and reduces amyloid aggregation in cells, worms an

63 stinal Th2 responses against Trichuris muris worms and Schistosoma mansoni eggs do not develop in mic

64 cient oxidative stress resistance in younger worms and survival effects in older worms.

65 ides as pheromones to communicate with other worms and to coordinate the development and behavior of

66 -22(sf21) mutants move faster than wild-type worms and, by optogenetic experiments, contract more.

67 nsion of H3K4me3 methyltransferase-deficient worms, and dietary MUFAs are sufficient to extend lifesp

68 lineages from insects, crustaceans, annelid worms, and fishes, we find more species in lineages with

69 granules) were up-regulated in daf-2 mutant worms, and knockdown of individual P-granule and other g

70 triction (CR) extends the lifespan of flies, worms, and yeast by counteracting age-related oxidation

71 Fan worms (Annelida: Sabellidae) are sessile polychaetes tha

72 Furthermore we show that the worms are capable of cleaving the host blood clotting pr

73 position, in which approximately half of the worms are dominated by each bacterial strain.

74 When worms are fed with two neutrally competing, fluorescentl

75 AXS studies indicate that, on average, three worms are formed per vesicle.

76 In this method, transgenic worms are generated in which a spliced leader (SL) RNA g

77 Larval stages of parasitic worms are killed in vitro by eosinophils in the presence

78 When used alone, the worms are not a particularly effective preservative.

79 Highly hydroxylated block copolymer worms are shown to be a suitable replacement for hydroxy

80 omprising Xenoturbella bocki and acoelomorph worms - are debated.

81 Chaetognaths (arrow worms) are a separate phylum (Chaetognatha) of small car

82 Last, we could reverse this 'worm arrhythmia' by the benzothiazepine S107, establishi

83 oles and challenging them with parasitic gut worms as adults.

84 pact on worms, infection intensity, types of worms (ascaris, hookworm, or trichuris), risk of bias, c

85 increase this rate experimentally by feeding worms at high bacterial density; in these conditions, th

86 ave activity against schistosomula and adult worms at low micromolar concentrations and therefore rep

87 ness, as demonstrated by significantly lower worm ATP levels and decreased intestinal worm burden and

88 n a Caenorhabditis elegans-Escherichia coli (worm-bacteria) experimental system in which the worm-for

89 cantly associated with increase in cartilage WORMS (beta = 0.2; 95% CI: 0.02, 0.4; P = .007).

90 biological iron and catalytic energy for the worm bioluminescence when coupled to a reduction process

91 asizing the possible role of ferritin in the worm bioluminescence.

92 reed (CHB) tends to have significantly lower worm burden and delayed and reduced egg production than

93 t show partial efficacy in terms of reducing worm burden and egg output.

94 wer worm ATP levels and decreased intestinal worm burden and fecundity.

95 eceptor Ss-DAF-12, significantly reduced the worm burden in MPA-treated mice undergoing hyperinfectio

96 effectiveness as the difference between the worm burden or number of cases and the number in absence

97 Conversely, worm burden was higher in Nmur1(-/-) mice than in contro

98 vestigate the total reduction in the overall worm burden, the total number of prevalent infection cas

99 limited, especially in travelers with a low worm burden.

100 1(-/-) KLRG1(+) ILC-2s significantly reduced worm burden.

101 esponses were marked by increased intestinal worm burdens, exacerbated lung injury, and increased pro

102 measurements are obtained automatically at a worm-by-worm resolution using a custom image processing

103 The nematode worm Caenorhabditis elegans (C. elegans) is a versatile

104 hat multiple small RNA-seq datasets from the worm Caenorhabditis elegans had shorter forms of miRNAs

105 ectly transferred between generations in the worm Caenorhabditis elegans Intergenerational transfer o

106 elates of lifespan extension in the nematode worm Caenorhabditis elegans, the fruit fly Drosophila, a

107 nterference (RNAi) is best understood in the worm Caenorhabditis elegans, where the dsRNA-binding pro

108 ns that comprise the whole body of the small worm, Caenorhabditis elegans However, to fully elucidate

109 The symbiosis between crayfish and their worms can shift from parasitism/commensalism to mutualis

110 inhibit PGE2 secretion, suggesting that the worms can synthesize PGE2 via a COX-independent pathway.

111 pathway suppress vitellogenesis in cultured worm cells.

112 Within a single worm, CEM responses are dissimilar, not determined by an

113 Normal adult worm clearance and enhanced AAM marker expression were o

114 pendent changes in gut function that promote worm clearance.

115 siliency and environmental dependence to the worm communities of buffalo.

116 d increase in the number of parasitic female worms compared with infected untreated mice.

117 ts are not up-regulated in the soma of daf-2 worms compared with the soma of control worms.

118 ed approach for performing killing assays in worms, compatible with standard assays performed on soli

119 modulated by exposure to light, despite the worm consuming the same amount of food.

120 In this article, we discuss the worm control options available, the translation of new b

121 The present-day distribution of velvet worms corresponds neatly to the ancient supercontinent G

122 the, undulation frequency, and wavelength of worms, crawling on surfaces show nonmonotonic behavior w

123 Worms defective in gut granule biogenesis exhibit defect

124 Here, field surveys identified changes in worm density, diversity and composition that were concom

125 , we contemplate the prospects for designing worm-derived immunotherapies for an ever-widening range

126 s or the entire germ-line program from daf-2 worms did not reduce their lifespan.

127 PQ-treated worms displayed higher maximum depolarization (peak of t

128 nt modalities do not kill the adult filarial worms effectively; hence, there is a need to identify an

129 Moreover, these block copolymer worms enable post-thaw gelation by simply warming to 20

130 dent on route of uptake, with filter feeding worms experiencing up to 130 times greater body burden r

131 Worms exposed to 10 mug L(-1), accumulated fluoxetine wi

132 g Hb2 infection, deficient mice had impaired worm expulsion and higher worm fecundity despite normal

133 and cytokine production, leading to delayed worm expulsion during infection with the gastrointestina

134 athway with indomethacin resulted in delayed worm expulsion in selenium-adequate mice.

135 on; goblet cell hyperplasia is abrogated and worm expulsion is compromised.

136 tions in intestinal function that facilitate worm expulsion.

137 muscle hypertrophy/hyperplasia, and impaired worm expulsion.

138 th mucus production, ultimately resulting in worm expulsion.

139 ls (0.4 ppm) had very little or no impact on worm expulsion.

140 Whilst the fossil record of polychaete worms extends to the early Cambrian, much data on this g

141 Ov-TSP-2 and TSP-3 were detected in whole worm extracts and excretory/secretory products of O. viv

142 mice had impaired worm expulsion and higher worm fecundity despite normal production of Th2-derived

143 uated type 2 cytokine response and increased worm fecundity in mice with a primary H. polygyrus baker

144 ng and accelerates aging of long-lived daf-2 worms fed a high glucose diet.

145 lmost exclusively from gut bacteria when the worms fed on higher fibre diets, whereas most of the enc

146 e in an all-or-nothing mode, such as bristle worms: females committed to reproduction spend roughly h

147 gnaling (IIS) can extend healthy lifespan in worms, flies, and mice, but it can also have adverse eff

148 Studies of cultured mammalian cells, worms, flies, rodents, simians, apes, and even humans, a

149 ecent findings based on studies in tunicate, worm, fly and vertebrate cells have revealed that the me

150 gene homologs in budding and fission yeast, worm, fly, fish, mouse, and rat on a single webpage.

151 exterior to intact, optically opaque marine worms for extended periods and with no observed adverse

152 as especially critical during preparation of worms for harsh desiccation (preconditioning) and during

153 m-bacteria) experimental system in which the worm-foraging behavior leads to a redistribution of the

154 ycobacterial load in the liver compared with worm-free mice.

155 In the present study, we obtained adult worms from abattoirs and characterized each worm on the

156 In addition, adult worms from F0 and F1 generations accumulated arsenite an

157 al data on viability and fertility of female worms from the single most comprehensive multiple-dose c

158 eering, when the sinusoidal movements of the worm generate an in-phase oscillation in the concentrati

159 stem across human, mouse, zebrafish, fly and worm genomes.

160 we have developed a new portal for parasitic worm genomes.

161 sented include outline-slide preparation and worm growth synchronization (15 min), mounting (20 min),

162 ng results of gut microbiota showed that the worms harbour several taxa in their gut lumen absent fro

163 mals such as Drosophila larvae or C. elegans worms has become an integral subject of biological resea

164 PQ-treated worms have enhanced avoidance behavior compared to untre

165 The unc-22(sf21) worms have well-organized sarcomeres.

166 ibitor, in filter and deposit feeding marine worms (Hediste diversicolor).

167 erapeutic effects of infections by parasitic worms (helminths) in some inflammatory disorders, such a

168 defining feature of infection with parasitic worms (helminths), as well as being responsible for wide

169 res of the cement proteins of the sandcastle worm, here we report a versatile and strong wet-contact

170 This study shows that mutations of HRPU-2, a worm homolog of mammalian hnRNP U, result in dysfunction

171 Utilizing the worm hospital and analysis of mutants, we observed that

172 The new device, named "worm hospital" allows us to perform the entire nerve reg

173 Here we show that worms implement a graded feeding response to the concent

174 farm bacteria benefit from farming by other worms in direct proportion to the fraction of farmers in

175 These animals do not differ from wild-type worms in histology, expression of key polarity genes, or

176 throughput of the study, we trapped multiple worms in parallel in a microfluidic device and illuminat

177 e establishment and maintenance of parasitic worms in their hosts.

178 on to impede blood clot formation around the worms in vivo.

179 isters to Arthropoda and Onychophora (velvet worms) in the superphylum Panarthropoda by morphological

180 fect the development and induce lethality of worms, in part, through modulating glucosylceramide.

181 longer than wild-type, particularly in older worms, independently of mianserin treatment.

182 and in vivo studies on biological cells and worms indicate the safety of halloysite, and tests for e

183 Parasitic worms infect billions of people worldwide.

184 However, the liver MNCs in male-only worm infection had a poor response to IL-33, though elev

185 ed in vivo into better clearance of helminth worm infection in mice.

186 T2L(+)F4/80(+) cells were lower in male-only worm infection than that of mixed infection.

187 ritional status, infection status, impact on worms, infection intensity, types of worms (ascaris, hoo

188 increased expression of vitellogenin by the worm intestine.

189 However the worm is protected by a robust cuticle that forms a barri

190 Our novel Au-decorated hybrid nano-worm is suitable for high-performance bio-sensing, as ev

191 nization suggests that heterogeneity between worms is driven by the low rate at which bacteria succes

192 normal fatty acid composition in young adult worms is due to sufficient fatty acid precursors provide

193 on of heat stimuli for the ibuprofen treated worms is lower than the wild-type.

194 witch in H3K4me3 methyltransferase-deficient worms is mediated at least in part by the downregulation

195 Inspired by the polychaete worm jaw, we report a novel approach to generate stiffne

196 e methods can also be readily adapted by any worm laboratory for real-time analysis of cell migration

197 Herein, a new worm like nanostructure with Zinc Oxide-gold (ZnO/Au) hy

198 Here, worm-like "filomicelles" that self-assemble in water fro

199 Molluscs include Solenogastres, with their worm-like bodies and behavior (see phylogenetic tree; Fi

200 ted MOGEN on synthetic datasets of a polymer worm-like chain model and a yeast genome at first, and t

201 at intermediate concentrations, and finally worm-like micelle structures at high concentrations.

202 ing quantitative posture analysis we explain worm locomotion as a composite of two modes: regular und

203 f bioturbation by the freshwater oligochaete worm Lumbriculus variegatus, and find good quantitative

204 skin-dwelling microfilarial progeny of adult worms (macrofilariae) and temporarily impedes the releas

205 nscriptome of the radiolar eyes from the fan worm Megalomma interrupta.

206 We hypothesized that detection of worm microRNAs (miRNAs) in serum can overcome the drawba

207 This novel worm model is ideal for screening molecules and genes to

208 Using a worm model of amyloid-beta proteotoxicity, GMC101, we re

209 m due to animal motion and show that, across worms, multiple neurons show significant correlations wi

210 ing an appropriate defense against parasitic worms, noxious substances, toxins, venoms, and environme

211 gical and genetic experiments with planarian worms, obtaining the same phenotypic outcomes predicted

212 We investigate three-segmented young worms of the marine annelid Platynereis dumerilii, with

213 worms from abattoirs and characterized each worm on the basis of the gene encoding nuclear internal

214 ect of paraquat (PQ)-induced OS on wild type worms on the function of the ASH polymodal neuron.

215 ested with two agricultural pests, beet army worm or two-spotted spider mites; pesticidal efficacy ex

216 the activity of Pol III in the gut of adult worms or flies is sufficient to extend lifespan; in flie

217 ing parameter and hence induces a vesicle-to-worm (or vesicle-to-sphere) morphological transition.

218 ltiple morphologies (spherical, cylindrical, worm, or vesicular) in equilibrium with each other.

219 red by the connectome of the C. elegans soil worm, organized into six interconnected communities, whe

220 ae and markedly impaired egg laying of adult worm pairs maintained in culture.

221 hannai (Gastropoda, Mollusca), and the sand worm Perinereis aibuhitensis (Polychaeta, Annelida) usin

222 probe three axes of invertebrate diversity: worms (Phylum Annelida), spiders (Class Arachnida) and i

223 , cell differentiation state, and/or overall worm physiological state.

224 tant populations, we can predict that as the worm pipefish moves northward, a wave of decreasing sele

225 proportion to the fraction of farmers in the worm population.

226 Microplastic ingestion by Tubifex worms poses a significant risk for trophic transfer and

227 ss sensitivity and subgroup analyses by age, worm prevalence, baseline nutritional status, infection

228 at target DCs can be designed from parasitic worm products and demonstrate the potential for ES-62 SM

229 Soluble worm products can block CLEC7A and Syk mRNA expression i

230 ed the behavioral deficits of tau transgenic worms, reduced phosphorylated and detergent-insoluble ta

231 ts of the XF96 include the limited number of worms required and the high throughput capacity due to t

232 rescue UPR(mt) signaling in atfs-1-deficient worms requiring the same UPR(mt) promoter element identi

233 ents are obtained automatically at a worm-by-worm resolution using a custom image processing workflow

234 We also show that Tubifex worms retain microplastics for longer than they retain o

235 secreted into the body cavity again when the worms return to developmental growth.

236 le gene expression in dauer larvae and aging worms, revealing gene expression changes consistent with

237 A map of a neuronal circuit in a marine worm reveals how simple networks of neurons can control

238 our model shows that the mutant changes the worm's behavior beyond affecting the thermal sensory sys

239 The worm's eggs, which cause the symptoms of schistosomiasis

240 rface likely play key roles in modifying the worm's local environment to ensure parasite survival.

241 red neural dynamics by mapping them onto the worm's low-dimensional postures, i.e. eigenworm modes.

242 mmalian prostaglandin synthesis affected the worm's motility but did not inhibit PGE2 secretion, sugg

243 acclimation and adaptation in the honeycomb worm, Sabellaria alveolata, a reef-building polychaete t

244 A marker for the parasitic worm Schistosoma was used in this study.

245 pSecS enzymes are phylogenetically closer to worm SepSecS.

246 In the absence of NCS-1, worms show delayed onset and a shorter duration of paral

247 d grooming allowed the colonization of large worm species and initiated symbiont-symbiont intraguild

248 xhibited a directed grooming response to all worm species, but were unable to remove small species.

249 studies of hybrid incompatibilities between worm species.

250 abundance and altered the behaviour of small worm species.

251 h typically hosted only two relatively small worm species.

252 s in native neurons and muscle cells between worm strains with and without BKIP-1 suggest that BKIP-1

253 We also find that behavioral trajectories of worms subject to oxidative stress resemble trajectories

254 legans in a paralytic killing assay, whereas worms succumbed to paralysis and death in its absence.

255 de insight into the mechanisms by which this worm suppresses inflammatory responses, an active compon

256 diversity as tadpoles have three times more worms than adults without their microbiota manipulated a

257 gesic-like effects and the minimum number of worms that allow for a statistically significant identif

258 Mutant worms that cannot farm bacteria benefit from farming by

259 habditis elegans with a necropsy analysis of worms that have died of old age.

260 turbella, are bilaterally symmetrical marine worms that lack several features common to most other bi

261 nt matrix, they were not detected in Tubifex worm tissue.

262 rapy achieves >90% depletion of Wolbachia in worm tissues leading to blockade of embryogenesis, adult

263 estingly, we find that TMC-1 is required for worms to avoid noxious alkaline environment.

264 f the applied model was verified by exposing worms to D-penicillamine and menadione.

265 of food deprivation in wild-type and mutant worms to determine the neural substrates of adaptive beh

266 metformin response pathway is conserved from worms to humans.

267 action among E3s is a conserved feature from worms to humans.

268 of the chlorophyll metabolite, exposing the worms to light increased adenosine triphosphate, reduced

269 regulation of the UPR(mt) is conserved from worms to mammals.

270 h reduced lifespan in organisms ranging from worms to mammals.

271 iments and the trophic transfer factors from worms to predators were about 1.

272 at of MBL homologs from human/mouse, fly and worm, to regulate alternative splicing.

273 tified in Caenorhabditis elegans using whole-worm transcriptional analyses more than a decade ago.

274 which undergo a thermally induced sphere-to-worm transition in dilute solution, were found to revers

275 Such vesicles undergo a vesicle-to-worm transition on heating to 150 degrees C, as judged b

276 Such vesicle-to-worm transitions offer an interesting new mechanism for

277 First, we analyzed the transcriptome from worms treated with the antidepressant mianserin, previou

278 significantly between treated and untreated worms; velocity in older adults decreased.

279 prediction, protein aggregation in yeast and worms was observed to increase when translation was glob

280 months, adjusted mean increase of cartilage WORMS was significantly smaller in the 5%-10% weight los

281 ter-based health-education tool 'The Vicious Worm' was developed to create awareness and provide evid

282 'Au-decorated hybrid nano-worm' was immobilized with a probe DNA from Vibrio Chole

283 f addition of various lipids directly to the worms, we suggest that glucosylceramide may be a key med

284 The worms were encapsulated in water-in-oil droplets to rest

285 lifespan of nematodes increased by 28% after worms were fed BB68, and this extension of lifespan was

286 tive effects of pCO2 on recruitment of these worms were still detectable.

287 eptors have begun to be studied in parasitic worms, where they are widely distributed and play key ro

288 cent behavior and promote roaming in fasting worms, whereas 5-HT produced by the NSM neurons acts on

289 The nano-worms which were evidenced by morphological, physical an

290 ance of small RNAs and for heritable RNAi in worms, which typically persist for a finite number of ge

291 restricted to the egg stage and female adult worms, while the H-IPSE protein is detectable only in ma

292 was probably a benthic, ciliated acoelomate worm with a single opening into an epithelial gut, and t

293 tends lifespan, promotes fat accumulation in worms with a specific enrichment of mono-unsaturated fat

294 mall, ubiquitous - but understudied - marine worms with a very simple body plan.

295 Worms with deficiency in BCKDH function manifest larval

296 paralytic behavior observed in hermaphrodite worms with loss-of-function dat-1 mutations.

297 essary, but not sufficient, for longevity of worms with mutations that increase lifespan.

298 in the absence of synaptic transmission, and worms with only one intact CEM show nonpreferential attr

299 Here we confronted C. elegans worms with the decision whether to cross a hyperosmotic

300 thological defects across species, including worm, zebrafish, and mouse.