ライフサイエンスコーパス: wound healing

1 in vivo for their ability to promote dermal wound healing.

2 the M2 polarization of macrophages in acute wound healing.

3 ely, progressive fashion promotes pathologic wound healing.

4 CR4, FAK, ASK1, and PP5 in ATII cells during wound healing.

5 anced arginine uptake mediates AS II-induced wound healing.

6 are shown to promote the corneal epithelial wound healing.

7 ic efficacy of platelet-derived proteins for wound healing.

8 ethod to study collective cell migration and wound healing.

9 ect of exogenous NO donor (NaNO2) on corneal wound healing.

10 that interrupts tissue remodeling in normal wound healing.

11 and improve keratinocyte differentiation and wound healing.

12 , that normally stimulate multiple phases of wound healing.

13 ation-related miRNAs with potential roles in wound healing.

14 losure of the pelvic floor improves perineal wound healing.

15 r angiotensin subtype 2 receptors in chronic wound healing.

16 udy the effects of COX-2 on colonic surgical wound healing.

17 d pathways including adhesion, migration and wound healing.

18 oblasts contract provisional matrices during wound healing.

19 ndotoxins and bacteria is crucial for normal wound healing.

20 3 HCs may provide a novel target to modulate wound healing.

21 zumab might also be associated with impaired wound healing.

22 ved in inflammation and proliferation during wound healing.

23 Cutaneous microvasculopathy complicates wound healing.

24 ave the potential to induce angiogenesis and wound healing.

25 on of cold physical plasma is the support of wound healing.

26 n of some inflammatory cytokines and delayed wound healing.

27 oblasts and production of collagen matrix in wound healing.

28 roliferation and re-epithelialization during wound healing.

29 hese processes are essential for normal skin wound healing.

30 racellular matrix deposition is required for wound healing.

31 ane organization during skin development and wound healing.

32 enomena such as the fingering instability or wound healing.

33 and differentiation can be uncoupled during wound healing.

34 in expression in the skin as well as delayed wound healing.

35 t and treatments of skin diseases, including wound healing.

36 ammation is critical for treating pathologic wound healing.

37 nduce signaling events essential for corneal wound healing.

38 ession during papilloma induction and during wound healing.

39 latelets with roles in both inflammation and wound healing.

40 metastasis, neuronal network development and wound healing.

41 ce also received an ear punch for evaluating wound healing.

42 egulate the local immune response and induce wound healing.

43 GFBR1 (type1 receptor of TGFbeta) to promote wound healing.

44 we show that SIRT1 is required for efficient wound healing.

45 ed in sustained bacterial burden and delayed wound healing.

46 y physiologically relevant processes such as wound healing.

47 n contributes to polarity acquisition during wound healing.

48 l-requiring enzyme 1 (IRE1alpha) in diabetic wound healing.

49 ls and macrophages and play central roles in wound healing.

50 pulate alpha9beta1 and/or alpha3beta1 during wound healing.

51 t stem cells (SCs) populations contribute to wound healing.

52 a key aspect of re-epithelialization during wound healing.

53 n regulating cellular traits associated with wound healing.

54 orly understood inputs for organogenesis and wound healing.

55 ion could promote fast and scarless gingival wound healing.

56 genesis of chronic inflammation, cancer, and wound healing.

57 erals (TM) play a role in skin integrity and wound healing.

58 s relevant to cancer, vascular diseases, and wound healing.

59 , bacteria can colonize the wound and impair wound healing.

60 Cre+) ) to determine the function of MLL1 in wound healing.

61 factors and conditions can lead to impaired wound healing.

62 host-pathogen defense, organ rejection, and wound healing.

63 did not interfere with skin development and wound healing.

64 lso reduced FPD development by promoting FPD wound healing.

65 are involved in developmental regulation and wound healing.

66 y a prolonged inflammatory phenotype in late wound healing.

67 induced angiogenesis, especially in diabetic wound healing.

68 actor for osteoarthritis (OA) and diminished wound healing.

69 (ASCs) accelerates the process of acid burn wound-healing.

70 ncludes wrinkles, pigmentation, and weakened wound healing ability.

71 osmetic dermatology, plastic surgery, scars, wound healing, acne, and isotretinoin was convened.

72 ion significantly reduced tube formation and wound-healing activity of PGE2 in human vascular endothe

73 We discovered in the mouse that during wound healing, adipocytes regenerate from myofibroblasts

74 with a concentration-dependent incidence of wound healing adverse events (WHAE).

75 PGE2 production is essential for intestinal wound healing after colonic surgery, possibly via its ef

76 rneal epithelial cells and the stroma during wound healing after corneal epithelial debridement.

77 Wound healing after corneal injury typically involves fi

78 Perineal wound healing after eAPR with preoperative radiotherapy

79 new type of matrix therapy agent on corneal wound healing after epi-off CXL in patients with keratoc

80 ffect of biological mesh closure on perineal wound healing after extralevator abdominoperineal resect

81 neal sensation and tear secretion and delays wound healing after injury.

82 ugh alpha3beta1 promotes this process during wound healing, alpha9beta1 has an inhibitory role, sugge

83 ferentiation, and migration and in epidermal wound healing and barrier repair.

84 of cell migration, division, morphogenesis, wound healing and cancer invasion.

85 ntral to many biological processes including wound healing and cancer progression, is sensitive to en

86 er, dysregulated macrophage function impairs wound healing and contributes to the development of fibr

87 Mll1(f/f)Lyz2(Cre+) mice display delayed wound healing and decreased wound macrophage inflammator

88 role in many physiological processes such as wound healing and development.

89 ial cells, and is essential for development, wound healing and disease.

90 From colony formation in bacteria to wound healing and embryonic development in multicellular

91 e effects were associated with inhibition of wound healing and gel contraction suggesting that nicoti

92 ow that ablation of ACF7 inhibits intestinal wound healing and greatly increases susceptibility to ex

93 ys, and cell behaviors to those activated in wound healing and identifies a repertoire of potential t

94 A possible link between delayed wound healing and increased risk of HIV acquisition dese

95 ed that MB improved skin viability, promoted wound healing and increased skin hydration and dermis th

96 last differentiation is a key process during wound healing and is dysregulated in lung diseases.

97 he formation of organs, tissue regeneration, wound healing and many disease processes, including canc

98 -derived exosomes may be involved in corneal wound healing and neovascularization, and thus, may serv

99 inhibition of calpain 1 activation improves wound healing and normalizes the mechanical properties o

100 Myofibroblasts participate in physiological wound healing and pathological fibrosis.

101 d for proteins involved in defense response, wound healing and protein phosphorylation when compared

102 al bandage significantly accelerates palatal wound healing and reduces the patient's morbidity.

103 his Review presents current understanding in wound healing and regeneration as two distinct aspects o

104 f FZD4 signaling on alveolar epithelial cell wound healing and repair, as well as on expression of el

105 okine secretion, contributed to the delay in wound healing and the inhibition of tumor growth and met

106 ng axons, while in adult tissues they aid in wound healing and the maintenance of intestinal cell pop

107 Wound healing and the management of chronic wounds repre

108 hatic regeneration occurs physiologically in wound healing and tissue repair, pathological lymphangio

109 anonical WNT-driven alveolar epithelial cell wound healing and transdifferentiation in vitro.

110 in [Ca(2+) ]i and promotes cell motility in wound healing and transwell migration assays.

111 model, the 10-lipid mixture accelerated skin wound healing and was also effective in healing wounds s

112 st that the 10-lipid mixture, because of its wound-healing and antimicrobial properties, can be benef

113 hort-lived, transplanted ASCs can accelerate wound-healing and reduce hair loss in acid-burn skin inj

114 d their contributions to tissue development, wound healing, and angiogenesis.

115 pithelial sites and contribute to psoriasis, wound healing, and anti-inflammatory effects during S. a

116 an impact allergic and autoimmune responses, wound healing, and anti-microbial defense.

117 migration important for normal development, wound healing, and cancer metastasis.

118 elf-organization in biofilms, embryogenesis, wound healing, and cancer metastasis.

119 processes, including embryonic development, wound healing, and cancer progression.

120 infection and is involved in tissue repair, wound healing, and clearance of apoptotic cells and cell

121 addition, the effect of SP in inflammation, wound healing, and corneal epithelial homeostasis in the

122 o been shown to favor embryonic development, wound healing, and even tumor growth, suggesting more co

123 hondrial oxidative phosphorylation (OXPHOS), wound healing, and gel contraction at different time poi

124 Selective inhibition of cell adhesion, wound healing, and invasion are demonstrated; near-infra

125 including those related to differentiation, wound healing, and metabolism.

126 T) is critical for embryonic development and wound healing, and occurs in fibrotic disease and carcin

127 revascularization are to relieve pain, help wound healing, and prevent limb loss.

128 racellular matrix organization, response for wound healing, and regulation of immune system processes

129 g of the links of FAs with OA, synovitis and wound healing, and reports newly identified serum and sy

130 erentiation of cells in stem cell therapies, wound healing, and the treatment of cancer.

131 ng, the evolution of bone microarchitecture, wound healing, and tumor growth.

132 ecules among cells and play crucial roles in wound healing, angiogenesis, and cancer, we hypothesized

133 luding propagated tissue damage and impaired wound healing, as occurs after spinal cord injury (SCI).

134 The wound healing assay reveals that inhibiting either BCL2L

135 s), in this short report we will explain the wound healing assay, also known as the "in vitro scratch

136 PDGF-mediated cell migration in an in vitro wound healing assay.

137 displayed reduced LPS-induced migration in a wound healing assay.

138 uman intestinal cancer cell line Caco-2 in a wound-healing assay, and in mice colon wounds.

139 All cell migration and wound healing assays are based on the inherent ability o

140 Wound healing assays revealed that MYH9(+/+) podocytes h

141 Furthermore, cell invasion and wound healing assays together with qRT-PCR determination

142 fects and promotes healing by using in vitro wound healing assays, human ex vivo and porcine in vivo

143 se results directly question the validity of wound-healing assays as a general means for measuring ce

144 d reduced migration speeds as measured using wound-healing assays.

145 MMP9 was induced during wound healing but at a significantly higher level in dia

146 we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds.

147 t of tissues and organs of the embryo and in wound healing, but palladin is also responsible for regu

148 mputation-free survival by 18%, and improved wound healing by 59%, without affecting mortality.

149 ression of Ep3 receptors in Mos/Mps improves wound healing by enhancing angiogenesis.

150 BRAF inhibitor vemurafenib accelerates skin wound healing by inducing the proliferation and migratio

151 sms of glucocorticoid (GC) downregulation of wound healing by interaction with the membrane bound GC

152 solving mediators of inflammation accelerate wound healing by preventing chronic inflammation and all

153 years or older and had at least one surgical wound healing by secondary intention, which was slow to

154 ws and experiences of living with a surgical wound healing by secondary intention.

155 Surgical wounds healing by secondary intention can have a devasta

156 ant tissue loss), and are known as 'surgical wounds healing by secondary intention'.

157 tions, particularly to "unexpected" surgical wounds healing by secondary intention.

158 on is a highly regulated process involved in wound healing, cancer metastasis, and morphogenesis.

159 During skin wound healing, CD26-positive cells accumulated over time

160 Wound healing complications were more prevalent in the b

161 No wound healing complications were noted.

162 iate) population had a distinct phenotype of wound healing, confirmed by results of studies inhibitin

163 Identifying natural drivers of wound healing could facilitate the development of new an

164 ological process term analysis revealed that wound healing-, cytoskeleton-, immune system-, stress re

165 point was the rate of uncomplicated perineal wound healing defined as a Southampton wound score of le

166 During the proliferative phase of cutaneous wound healing, dermal fibroblasts are recruited into the

167 used for many clinical indications including wound healing due to the high concentrations of growth f

168 ay play a key role in tissue homeostasis and wound healing during Th2-mediated immune responses, such

169 altered cadherin distributions at junctions, wound healing dynamics, and paracellular permeability.

170 n leads to enhanced lung disease and altered wound healing dynamics.

171 Although the wound healing effects of nitric oxide (NO) are known, th

172 tions demonstrated clearance of bacteria and wound healing following repeated i.v. administration of

173 Periodontal wound healing has been accelerated by different low-leve

174 Modulating conjunctival wound healing has the potential to improve outcomes afte

175 rosis and myofibroblast formation in corneal wound healing have not been fully elucidated.

176 hological processes including embryogenesis, wound healing, host immunity, and tumor suppression.

177 y responses to clear infections and initiate wound-healing; however, excessive responses cause inflam

178 gnized as a central clinical issue for RDEB, wound healing impairment has been only marginally invest

179 ival and hypertrophic-like scar-forming skin wound healing in a pig model, and used three-dimensional

180 based coacervate delivery vehicle to improve wound healing in a porcine model.

181 ls with OA, synovitis, adipokine levels, and wound healing in a pre-clinical obese mouse model of OA.

182 regulation of miR-200c at the early phase of wound healing in aged skin.

183 t, melanization is an important component of wound healing in arthropods.

184 ization is not an indispensable component of wound healing in arthropods.

185 effects and mechanism of AS II on intestinal wound healing in both in vitro and in vivo models.

186 rove beneficial in the treatment of impaired wound healing in diabetes.

187 sin-converting enzyme inhibitor captopril on wound healing in diabetic and aged mice with further val

188 angiotensin system is implicated in abnormal wound healing in diabetic and older adults.

189 +DHA promotes corneal nerve regeneration and wound healing in diabetic mice and could potentially be

190 transfer significantly accelerated cutaneous wound healing in diabetic mice through facilitating angi

191 monstrate the effect of plasma treatment for wound healing in diabetic rats.

192 evaluating antiretroviral effects on genital wound healing in future clinical trials.

193 bronectin was found to significantly improve wound healing in irradiated skin and was associated with

194 Here, using an in vivo model of cutaneous wound healing in mice, we provide evidence that GPNMB is

195 alization, granulation formation, and proper wound healing in mice.

196 langiocyte cell line and demonstrated potent wound healing in mice.

197 lular and molecular mechanisms that regulate wound healing in mouse tail epidermis.

198 blation of epidermal caspase-8 as a model of wound healing in Mus musculus, we analyzed the signaling

199 and VEGF189 loaded scaffolds promoted dermal wound healing in normal and diabetic rats.

200 r occludin, down-regulation had no impact on wound healing in normal scratch assays, but after subjec

201 Compared to skin, wound healing in oral mucosa is faster and produces less

202 s the method can be readily applied to image wound healing in other injured or diseased tissues, or t

203 We concluded that corneal endothelial wound healing in rabbits has different outcomes dependin

204 elial cells (ATII) are instrumental in early wound healing in response to lung injury, restoring epit

205 ain overexpression significantly accelerated wound healing in STZ-induced diabetic mice.

206 , an improved prodrug of TFV, interfere with wound healing in the human FRT.

207 c mucosa was sufficient to impair epithelial wound healing in vivo.

208 cerebrovascular endothelial cells and, in a wound-healing in vitro assay, impaired cell motility and

209 through distinct, yet overlapping phases of wound healing, including hemostasis, inflammation, proli

210 come was assessment of wound healing using a wound healing index (WHI).

211 induced in hyperproliferative states such as wound healing, inflammation and cancer.

212 on of gene expression, cellular homeostasis, wound healing, inflammation, allergy, autoimmunity, and

213 mediators of stress signals, are also potent wound healing inhibitors.

214 terol pathway and block the synthesis of the wound-healing inhibitors farnesyl pyrophosphate (FPP) an

215 te that QHREDGS is a promising candidate for wound-healing interventions that enhance re-epithelializ

216 Wound healing is a biological process directed towards r

217 Wound healing is a complex cellular and biochemical proc

218 Delayed wound healing is a major complication of diabetes occurr

219 Epithelial wound healing is an evolutionarily conserved process tha

220 Wound healing is complex and highly orchestrated.

221 IL-10-induced HA synthesis for regenerative wound healing is demonstrated by inhibition of HA synthe

222 Wound healing is essential to repair the skin after inju

223 hese findings are novel in understanding how wound healing is regulated.

224 Wound healing is significantly delayed in irradiated ski

225 An important phase of wound healing is the generation of a basal epithelium wh

226 contributes to abnormal scarring or delayed wound healing is widely taught and practiced; however, i

227 niche and generate alternatively activated, wound healing macrophages.

228 sis and help delineate an altered profile in wound-healing markers during ONJ development.

229 ated to FHs promote tissue regeneration in a wound-healing model of mouse submandibular glands (mSMGs

230 teins claudin-1 and occludin in ex vivo skin wound healing models and tissue samples of acute and chr

231 x and modes of trauma in PTSD, including one wound-healing module downregulated in men exposed to com

232 The impaired wound healing of diabetic wounds is attributed to low le

233 thy is characterized by proteins involved in wound healing, ongoing fibrosis, and inflammation.

234 on tube formation, nitric oxide production, wound healing or cell proliferation in HUVEC/HUV-ST.

235 blood vessel regression during development, wound healing or IFNgamma-mediated, pregnancy-induced re

236 bacteria did not inhibit corneal epithelial wound healing or increase clinical inflammatory signs in

237 thelial cells move randomly; however, during wound healing, organism development, cancer metastasis,

238 ortance of the microbial communities in skin wound healing outcome.

239 an dysfunction, ventilator days, and time to wound healing (P > 0.05) were similar.

240 ating TNFalpha and IL-1beta during the early wound healing phase and reduced inflammation by downregu

241 n by downregulating IL-1beta during the late wound healing phase.

242 matrix, which mimics the fetal regenerative wound healing phenotype with reduced fibrosis.

243 T cells plays a crucial role in the cardiac wound healing process after myocardial infarction.

244 othelial cellular traits associated with the wound healing process and may also be able to regulate t

245 s implies a potential regulatory role in the wound healing process and, thus highlights their potenti

246 A dysregulation in this wound healing process leads to fibrosis.

247 the absence of LPA1 mitigates the epithelial wound healing process.

248 ut the function of DM in corneal endothelial wound healing process.

249 The cutaneous wound-healing program is a product of a complex interpla

250 nomas are well known to activate a prolonged wound-healing program that promotes malignant transforma

251 ent second messenger and master regulator of wound-healing programs, it is unknown what initiates the

252 ecyparis obtusa extract, and we describe the wound-healing properties of its combination of 10 major

253 ion on CMR and increases in inflammation and wound healing proteins on post-MI day 7.

254 Uncomplicated perineal wound healing rate at 30 days was 66% (33/50; 3 not eval

255 ut spares other macrophage functions such as wound healing, reactive oxygen species production and ph

256 ibrillogenesis, promoting corneal epithelial wound healing, regulating gene expression and maintainin

257 (GFBLs) strongly regulated the expression of wound healing-related genes.

258 the mechanism by which NO modulates corneal wound healing remains unclear.

259 orneal epithelial cell migration and corneal wound healing, respectively.

260 Lung fibrosis is an unabated wound healing response characterized by the loss and abe

261 t a mechanism by which the normal epithelial wound healing response is "hijacked" to promote invasion

262 and antiviral host defense during the normal wound healing response.

263 lcoholic hepatitis, PTX3 participates in the wound-healing response and attenuates LPS-induced liver

264 ponses may alter the homeostatic balance and wound-healing response of gingival connective tissues af

265 an bladder cancer xenografts could trigger a wound-healing response that mobilizes quiescent tumor st

266 lly, PTX3 mediated the hepatic stellate cell wound-healing response.

267 activated myofibroblast differentiation and wound healing responses in cultured pericytes, but domai

268 Maladaptive wound healing responses to chronic tissue injury result

269 inding domains, has roles in vasculogenesis, wound healing responses, and fibrogenesis and is upregul

270 promote tissue regeneration in which classic wound-healing responses predominate.

271 ly, generating myofibroblasts and associated wound-healing responses.

272 duction, the blinking reflex, and epithelial wound healing, resulting in loss of transparency and vis

273 r hair removal, chemical peel, dermabrasion, wound healing, safety, scarring, hypertrophic scar, and

274 analyses using thousands of model-simulated wound-healing scenarios, we identified five key processe

275 In addition, PEDF+DHA accelerated corneal wound healing, selectively recruited type 2 macrophages,

276 In cutaneous wound healing, skin cells migrate from the wound edges i

277 ted to stress responses and apoptosis at the wound healing stage, signaling pathways including Wnt an

278 the IL-27 receptor (Il27Ra(-/-)) attenuates wound healing, suggesting an essential role for IL-27 si

279 have shown that cell-based therapies improve wound healing, the recruitment of therapeutic cells to b

280 es derived from Ov-GRN-1 are leads for novel wound healing therapeutics, as they are likely less immu

281 ication of 0.5% PVI could promote acute skin wound healing though increased expression of TGF beta le

282 L3), are transcription factors implicated in wound healing, tubulogenesis and cancer.

283 situations such as normal aorta, lungs, and wound healing, tumors, and placenta, as well.

284 Secondary outcome was assessment of wound healing using a wound healing index (WHI).

285 ases LNCaP cell proliferation, migration and wound healing, verifying loss drives a cancer phenotype.

286 oblast differentiation, gel contraction, and wound healing via mitochondria stress through nicotinic

287 PVI treatment enhanced wound healing via promotion of expression of alpha SMA a

288 PMN-MP/MPO-dependent inhibition of IEC wound healing was due to impaired IEC migration and prol

289 stress, which is normally present in wounds, wound healing was impaired.

290 men; 9 women; mean [SD] age, 31 [10] years), wound healing was significantly faster in the matrix the

291 ound in HAT-L4 knockout mice in hair growth, wound healing, water repulsion and body temperature regu

292 To understand how stress signals inhibit wound healing, we investigated the role of membranous gl

293 However, for claudin-1 effects on scratch wound healing were more pronounced when TJs could form.

294 cations, such as graft infection and delayed wound healing, were seen in 6 patients; 8 patients exper

295 HTS is the result of dysregulated wound healing, where excessive collagen and extracellula

296 s high levels of MMP9 expression in diabetic wound healing, which represents a novel mechanism for im

297 whether Pseudomonas species directly impair wound healing, wild-type mice were infected with Pseudom

298 n resulted in significantly impaired scratch wound healing, with delayed migration and reduced prolif

299 arization in both physiologic and pathologic wound healing, with particular attention to diabetic wou

300 ious complication that can result in delayed wound healing, wound breakdown, fistula formation, and c