ライフサイエンスコーパス: wounding

1 growth and prevented new HF formation after wounding.

2 a robust LUC activity solely in response to wounding.

3 ial Ca(2+) uptake and mtROS production after wounding.

4 red for the response to fungal infection and wounding.

5 1A) has been implicated in fibrosis and skin wounding.

6 oth the nucleus and cytoplasm at 1 day after wounding.

7 n was related to the intensity of mechanical wounding.

8 nucleus in the dermis at 2 and 7 days after wounding.

9 erate epidermal covering following cutaneous wounding.

10 lso mainly enhanced by drought and little by wounding.

11 Arabidopsis thaliana subjected to mechanical wounding.

12 ferlin-containing vesicle behavior following wounding.

13 expression of genes involved in response to wounding.

14 ve movement of the epithelium in response to wounding.

15 but failed to accumulate JA or JA-Ile after wounding.

16 mes and release norepinephrine after scratch wounding.

17 es, 254 changed significantly in response to wounding.

18 RN1 increased the plant response to physical wounding.

19 ocyte-derived norepinephrine increased after wounding.

20 egeneration and early epidermal repair after wounding.

21 d in the corneal epithelium and stroma after wounding.

22 the interfollicular epidermis upon epidermal wounding.

23 = .04) in skin when measured 72 hours after wounding.

24 at precise times during the first week after wounding.

25 ing their inability to regenerate hair after wounding.

26 ate the in vivo role for IL-22 in acute skin wounding.

27 in's dermal compartment after full-thickness wounding.

28 ith time, maturing as early as 14 days after wounding.

29 investigate mechanisms of calcium entry upon wounding.

30 cent and fibrotic markers 2 to 4 weeks after wounding.

31 broblast cytoskeletal dynamics after scratch-wounding.

32 ns (P-proteins) that plug sieve plates after wounding.

33 ack by pests and pathogens or from damage by wounding.

34 nnate acute inflammatory reaction to corneal wounding.

35 elopment and for a response to pathogens and wounding.

36 mino acid metabolism were up-regulated after wounding.

37 elements as well as sieve plate plugs after wounding.

38 er-adhesion, the opposite of what happens on wounding.

39 hyperbaric oxygen treatment (HBOT) following wounding.

40 stimulates epithelial repair following skin wounding.

41 read to neighboring cells, within seconds of wounding.

42 ated at the wound edges within 30 minutes of wounding.

43 nvironment and for monolayer resealing after wounding.

44 and restoration of tissue homeostasis after wounding.

45 as induced by methyl jasmonate treatment and wounding.

46 ction in this pathway impairs survival after wounding.

47 h numbers at the site of tissue infection or wounding.

48 l Ca(2+) that is critical for survival after wounding.

49 ation was evaluated after corneal epithelial wounding.

50 growth factor-beta (TGF-beta) after corneal wounding.

51 ficiency in restoring the skin barrier after wounding.

52 to hair loss and impairs regeneration after wounding.

53 such as flooding, nutrient deprivation, and wounding.

54 37 and dsRNA, a condition that mimics normal wounding.

55 ise only asynchronously with growth or after wounding.

56 g cells in the early phase within 24 h after wounding.

57 erentially expressed in response to parental wounding.

58 asite types but is not induced after sterile wounding.

59 inally resulting in immediate lethality upon wounding.

60 ls resembled the syncytia caused by physical wounding.

61 the regeneration of the new epidermis after wounding.

62 was performed on days 3, 7, 10, and 14 after wounding.

63 a similar manner in both genotypes following wounding.

64 oduli of living cells during migration after wounding.

65 Intense wounding (23.5 cm(2)/g) induced an approximately 2.5- an

66 egeneration of skin and hair follicles after wounding--a process known as wound-induced hair neogenes

67 Nucleotides released after scratch wounding activate purinergic receptors, leading to a dis

68 To date, nothing is known about how wounding activates DUOX.

69 Taken together, our results indicate that wounding alone activates the PO cascade in B. mori.

70 uced by real and mimicked herbivory, but not wounding alone.

71 ellipodia, focal adhesions, and repair after wounding, along with impaired H2O2 responses after expos

72 al kinase (JNK) signaling, which occurs upon wounding, also correlated with syncytium formation induc

73 o receive acute treatment (immediately after wounding and 24 hours later) with an aCT1 gel formulatio

74 Next, we treated RSRE::LUC plants with wounding and a range of rapidly stress-inducible hormone

75 In vitro wounding and collagen gel contraction assays were used t

76 ed to increase stem cell proliferation after wounding and displayed defects in tissue remodeling.

77 nse to specific stresses and determined that wounding and drought differentially alter oxylipin profi

78 ocal microscopy, we showed that both aseptic wounding and Escherichia coli inoculation triggered macr

79 Both, wounding and exposure of 4T1 cells to SDF-1alpha not onl

80 ally cleaved HCII forms were detected during wounding and in association with bacteria.

81 the chemotactic process under conditions of wounding and infection from video microscopy data.

82 le and decapentaplegic (dpp), in response to wounding and infection in adult Drosophila.

83 , preparing the body for situations in which wounding and infection may be more likely (social isolat

84 ls exhibit complex regulation in response to wounding and infection, each is expressed in a subset of

85 e for GC-C signaling in facilitating mucosal wounding and inflammation, and further suggest that this

86 nces lymphangiogenesis following both dermal wounding and inflammatory challenge.

87 roduces OPDA but no detectable JAs following wounding and looper infestation; unexpectedly, substanti

88 lowground or toward damaged leaves following wounding and MeJA treatment to young leaves, suggesting

89 lants together with induction of MusaSAP1 by wounding and methyl jasmonate treatment indicated possib

90 We found that upon wounding and methyl jasmonate treatments, MYB11 and ZML2

91 cultured epithelial cells was upregulated by wounding and neutrophil elastase.

92 Airway epithelial responses to wounding and osmotic stress were assessed in primary air

93 endages and is induced in the epidermis upon wounding and other stressors.

94 Stimuli ranging from wounding and pathogen attack to the distribution of wate

95 n inactive form of JA that accumulates after wounding and pathogen attack, is unknown.

96 hibitory effects were attenuated by both AEC wounding and pertussis toxin, indicating the involvement

97 n with enhanced expression in models of skin wounding and psoriatic-like inflammation.

98 arcomeric component, is strongly elevated by wounding and tissue injury.

99 largely impaired in 12OH-JA-Ile levels upon wounding and to a lesser extent in 12COOH-JA-Ile levels.

100 e an explanation for the association between wounding and tumorigenesis.

101 acellular space is triggered by insults like wounding and ultraviolet radiation, resulting in stimula

102 gular cycles of synchronous tissue shedding (wounding) and repair that occur during menstruation befo

103 many different signals including pathogens, wounding, and abiotic stresses.

104 antly among background strains of mice after wounding, and all correlated such that the highest Ptgds

105 erous genes involved in pathogen resistance, wounding, and cell wall biogenesis.

106 ll molecule AMD 3100 abolished the effect of wounding, and decreased cell proliferation, collagen dep

107 Dorsal is activated on wounding, and Dif and Dorsal are required for the sustai

108 ion increased dramatically immediately after wounding, and down-regulation of transient receptor pote

109 se to challenges including oxidative stress, wounding, and shear stress.

110 ivated Tregs accumulated in skin early after wounding, and specific ablation of these cells resulted

111 scopy) and nuclear Atox1 are increased after wounding, and that wound healing with and without Cu tre

112 tal injury (such as UV exposure and physical wounding), apoptosis is an important mechanism regulatin

113 formation following JNK hyperactivation and wounding appeared to be direct disassembly of FA complex

114 ritically injured casualties within hours of wounding appears to be effective, with a minimal mortali

115 ature, and do not degranulate in response to wounding as effectively as mast cells of fibrotic wounds

116 rabidopsis, AtCML37 is induced by mechanical wounding as well as by infestation with larvae of the ge

117 ML3 gene expression is promoted by wounding as well as by the phytohormone jasmonic acid an

118 altered the inflammatory reaction to corneal wounding, as evidenced by a 114% increase (P < 0.01) in

119 After wounding, Ash1l mutation leads to delayed re-epithlializ

120 are released from astrocytes in an in vitro wounding assay also induce COX-2 expression through a PL

121 platform on which a reproducible electrical wounding assay was conducted to model RPE damage.

122 l substrate and restrained EC migration in a wounding assay.

123 e Sensing (ECIS) and reproducible electrical wounding assays to model and quantitatively study AMD.

124 d-responsive genes in response to mechanical wounding, attack by Manduca sexta larvae, and Prosystemi

125 at sap is released from cucurbit phloem upon wounding but contributes negligibly to total exudate vol

126 gulates induction of TGase2 expression after wounding but does not affect expression of the component

127 equired for known innate immune responses to wounding but instead promotes actin-dependent wound clos

128 cascade promotes innate immune responses to wounding but is not required for other aspects of wound

129 creased in dermal fibroblasts following skin wounding but was downregulated in tumour stroma.

130 d cell migration over the denuded area after wounding but was rescued by increasing HuR levels.

131 educes angiogenesis in response to cutaneous wounding, but enhances lymphangiogenesis following both

132 K) pathway upregulates Mmp1 expression after wounding, but that Mmp1 is expressed independent of the

133 cation is induced by external inputs such as wounding, but the molecular mechanisms that link this st

134 regulates plant response to herbivore attack/wounding by modulating the SA-JA crosstalk through AtSR1

135 servations indicate that cell mass lost upon wounding can be replaced by polyploidization instead of

136 ponses and help to explain how pathogens and wounding can have general effects on growth.

137 1), nutrient deficiency (case study 2), and wounding (case study 3).

138 We show that skin wounding causes local production of mtROS superoxide at

139 However, after wounding, cells reversibly switch to producing an excess

140 te, salicylic acid, ultraviolet B light, and wounding, chosen on the basis of identified cis-regulato

141 e induction of cellular migration by scratch-wounding confluent cell cultures, culturing under subcon

142 nation of bacteria, chronic inflammation and wounding cooperate to trigger skin cancer.

143 on was profoundly induced in diabetes and by wounding, correlating with diminished levels of proangio

144 Wounding downregulated B2AR, tyrosine hydroxylase, and p

145 rile inflammatory response only months after wounding; earlier periods showed resolution of the initi

146 As an early systemic response, wounding elicited transient accumulation of jasmonates a

147 We report that wounding elicits expression of the Wnt inhibitor notum p

148 recent study shows that, upon stretching or wounding, epithelia display a fast proliferative respons

149 Wounding epithelial cell sheets causes activation of the

150 integrated into RSRE::LUC parent plant, with wounding, flg22, and freezing, established a differentia

151 which was highly upregulated in response to wounding followed by ethylene, methyl jasmonate and ABA

152 ts seen previously using the more aggressive wounding following dermabrasion.

153 ry intention, and harvested at 14 days after wounding for morphometrics and standard Fourier transfor

154 rdering the wound, which become motile after wounding, forming dynamic actin protrusions along the wo

155 ncytium formation, including that induced by wounding, genetic loss of FA proteins, or local JNK hype

156 Further, CsCCD4c was up-regulated by wounding, heat, and osmotic stress, suggesting an involv

157 n plants to those usually produced following wounding, herbivory and pathogen invasion.

158 Upon wounding, however, PKD1-deficient mice exhibited delayed

159 mily members was markedly downregulated upon wounding in both young and aged mice, with an exception

160 Skin wounding in C. elegans triggers a Ca(2+)-dependent signa

161 glands in reconstituting the epidermis after wounding in humans.

162 SD 4%) injuries but also allows for repeated wounding in microfluidic environments.

163 erlin-containing vesicles following cellular wounding in muscle cells and examine the role of microtu

164 and vesicle-organelle fusion in response to wounding in muscle cells.

165 a1 and beta3 were upregulated in response to wounding in NL corneal epithelial cells (CECs), whereas

166 In an adult model of chronic wounding in zebrafish, we show that repeated wounding wi

167 ished that emission of GLVs is stimulated by wounding incurred mechanically or by aphids, but release

168 es of both classes were generally induced by wounding, indicating that a common initial gene expressi

169 Specifically, wounding induced both 12-OPDA and JA levels, whereas dro

170 Laser-wounding induced rapid recruitment of approximately 30 m

171 Wounding induced the synthesis of mainly chlorogenic aci

172 lso, caterpillar feeding, but not mechanical wounding, induced foliar RIP2 protein accumulation.

173 thermore, mast cell deficiency did not alter wounding-induced inflammation and new tissue formation o

174 Silencing of Fos or of TGase2 aborts the wounding-induced mosquito killing of P. falciparum.

175 ormones abscisic and indole acetic acid, and wounding-induced up-regulation of the defence signalling

176 We now demonstrate that wounding induces benign tumors (papillomas and keratoaca

177 Membrane wounding induces dysferlin-containing vesicle-vesicle fu

178 Additionally, we found that acute wounding induces epithelial cell mmp9 expression and is

179 Wounding induces lysosome exocytosis and endocytosis of

180 Wounding induces the expression of VEFG, which may modul

181 Tissue wounding induces the rapid recruitment of leukocytes.

182 results in epidermal inflammation, and skin wounding induces tumours.

183 extracts of Arabidopsis leaves subjected to wounding, infection by PstAvr, infection by a virulent s

184 upregulated coding genes mostly involved in wounding, inflammation and defense, whereas the downregu

185 Conversely, wounding inhibits BCR signaling and internalization by d

186 Dynamic analysis revealed that wounding initiated a wave of motion coordination from th

187 nd and Choctaw) were studied under different wounding intensities (A/W) during storage.

188 cated, e.g., 2D cell migration after scratch-wounding, invasion of cancer cells, and finally, myofibr

189 he corneal epithelial barrier recovery after wounding is an important contributing factor to the deve

190 double-stranded RNA (dsRNA) released during wounding is both necessary and sufficient to stimulate W

191 Our findings explain why wounding is linked to formation of ECM-rich scar tissue

192 n young skin, re-epithelialization following wounding is perturbed.

193 lls participate in tissue regeneration after wounding, it is unclear whether these cells also contrib

194 but repressed by Gram-negative infection or wounding; its role is to limit infection-induced melaniz

195 EFN secretion is commonly induced after wounding, likely owing to a jasmonic acid-induced cell w

196 Environmental challenges such as wounding, low temperature, oxidative states and pathogen

197 electrical signals, which can be induced by wounding, may also enable signalling over relatively lon

198 Data included demographics, wounding mechanism, injuries sustained, prehospital time

199 The lack of reproducible, high-throughput wounding methods has hindered single-cell wound repair s

200 mechanistic studies impossible with current wounding methods.

201 WST-1 proliferation and cell-wounding-migration assays were assessed in IEC-6 cells e

202 In response to wounding, migratory epithelia produce CXCL10, thymic str

203 on and healing was also observed in a dermal wounding model with deletion of Mapk14.

204 After wounding, multiple cell types interact to form a fibrova

205 Neither mechanical wounding nor the application of jasmonic acid, but infes

206 After wounding of an epithelium, the cells bordering the wound

207 Mechanical probe-induced micro-wounding of both endothelia and epithelia suggests that

208 Mechanical wounding of freshly-pruned canes drastically shortens th

209 generating epidermis after partial-thickness wounding of human skin.

210 Mechanical wounding of plants triggers the release of a blend of re

211 In the present study, we found that wounding of rat ATII cells promoted increased associatio

212 Here, we show that laser wounding of the Drosophila embryo epidermis triggers an

213 with different AIB1 genotypes and subsequent wounding of the grafts revealed that the defective heali

214 Consequently, this needle-puncture wounding of the insect gut can be developed for screenin

215 These cells rapidly responded to wounding of the lens epithelium with population expansio

216 erin) at cell-cell junctions, and mechanical wounding of the monolayer stimulates VE-cadherin complex

217 s endothelium in superficial veins following wounding of the overlying skin.

218 The inevitable wounding of the roots caused by harvesting triggers an o

219 bol-13-acetate (TPA) and (ii) full-thickness wounding of the skin.

220 y abdominal inoculation coupled with aseptic wounding of the thorax.

221 the present study, the effect of mechanical wounding on freshly-pruned canes was tested to increase

222 tissue but are rapidly upregulated following wounding on keratinocytes bordering wound edges.

223 ains we could demonstrate that the effect of wounding on tumor growth and SDF-1alpha levels is host d

224 Wounding one cotyledon activated the reporter in both ae

225 is genotypes that were damaged by mechanical wounding or by insects of various feeding guilds (pierci

226 blishment of polarity after either monolayer wounding or calcium switch.

227 er several abiotic-stress conditions such as wounding or exposure to salinity, cadmium, and low tempe

228 Wounding or exposure to sphingomyelinase triggered endoc

229 that are generated in plants in response to wounding or flaming.

230 oes not support the concept of a significant wounding or immune response following biopsy in the abse

231 ns and also under multiple stresses, such as wounding or infection.

232 investigated in Norway spruce saplings after wounding or inoculation with the fungal pathogen Ceratoc

233 ed is even more acute after tissue damage by wounding or pathogenic infection.

234 Importantly, after wounding or simulated herbivory, IRcdpk4/5 plants accumu

235 ession in plants that had leaves elicited by wounding or simulated herbivory.

236 ctional vascular plexus such as in models of wounding or tumour development.

237 Here we demonstrate that after wounding or ultraviolet type B irradiation, melanocyte s

238 cumulation of tuberonic acid (12OH-JA) after wounding originates partly through a sequential pathway

239 nvolved in plant stress responses, including wounding, perhaps to evoke plant defense.

240 idence is presented that GPAT7 is induced by wounding, produces suberin-like monomers when overexpres

241 ative clonal analysis reveal that, following wounding, progenitors divide more rapidly, but conserve

242 sh larval tail fins as a model, we find that wounding rapidly activated SFK and calcium signaling in

243 However, wounding recruits these cells from the follicle to the w

244 Mechanical wounding reduced fibroblast aromatase activity but incre

245 ow these processes are coordinated following wounding remained unclear.

246 Restoring homeostasis after wounding requires the coordinated actions of epidermal a

247 We show that after amputation, a wounding response precedes rapid re-organization of the

248 which may reflect a lesser role for HSCs in wounding response to biliary injury.

249 ycosylating, and acylating activities in the wounding response.

250 o lignin biosynthesis as part of its natural wounding response.

251 nelle functions, and is related to touch and wounding responses.

252 Wounding resulted in a decrease of preformed 12-oxo-phyt

253 locking OPN expression at sites of cutaneous wounding resulted in reduced granulation tissue and scar

254 Corneal epithelial wounding resulted in significant delay in recovery of th

255 the recruitment of cellular events following wounding, resulting in a lack of bacterial clearance and

256 Wounding results in weakening of desmosomal adhesion to

257 he cotyledon-to-root JA signal velocities on wounding, revealing two distinct phases of JA activity i

258 ponses, innate pathogen sensing, response to wounding, small nucleolar RNAs, and the ubiquitin-proteo

259 In contrast, upon wounding, stem cell progeny from multiple compartments a

260 , demonstrating their plasticity to adapt to wounding stimuli.

261 By simply increasing wounding stress intensity it is possible to enhance the

262 n as AtCAMTAs) can respond differentially to wounding stress.

263 regulate plant responses to herbivore attack/wounding stress.

264 under both pathogen infection and mechanical wounding stress.

265 Wounding stresses resulting from fresh-cut processing ar

266 In wounding studies, Wfdc1-null mice exhibited an elevated

267 However, little is known about how wounding, such as following surgery, biopsy collection o

268 hyde accumulation was observed in Sei-0 upon wounding, suggesting that AtAAS and subsequently phenyla

269 onsive enhancers during development and upon wounding suggests cooperation with distinct TFs in diffe

270 , salicylic acid, and gibberellic acid or by wounding, temperature, and light, factors known to affec

271 We show here that wounding the adult C. elegans skin triggers a rapid and

272 in the abdomen and additionally showed that wounding the cuticle of the abdomen results in decreased

273 , modulates hair follicle regeneration after wounding the skin of adult mice.

274 inhibits intestinal epithelial repair after wounding, the mechanisms that control Stim1 expression r

275 Upon wounding, the number of epidermal and dermal monocytes a

276 After wounding, the P2Y2 receptor mRNA expression increased, a

277 urrounding tissue, and that after surgery or wounding, the resulting RI mismatch between the activate

278 Our work shows that, immediately after wounding, there was a dramatic cytoskeleton remodeling c

279 Following full thickness wounding, there was no migration of tdTomato-labeled cel

280 oordinating the response of keratinocytes to wounding through up-regulation of TGF-beta1 and other fa

281 ssociation between the duration of time from wounding to arrival at Landstuhl Regional Medical Center

282 he transcriptional response to infection and wounding to identify genes that contribute to the natura

283 after cellular damage caused by pathogens or wounding to induce innate immunity by direct binding to

284 hinery that directs repair, we applied laser wounding to live mammalian myofibers and assessed transl

285 3 link the earliest events of mammalian skin wounding to regeneration and suggest potential therapeut

286 induced by drought, cold, abscisic acid, and wounding treatments.

287 Upon wounding, Tregs induce expression of the epidermal growt

288 In sum, wounding triggered transient sieve tube occlusion, enhan

289 In adult mammals, wounding triggers an inflammatory response that can exac

290 Wounding triggers the formation of arrays of Rho GTPases

291 Skin wounding triggers tumour formation in InvEE mice via a m

292 lites produced as a response to potato tuber wounding, using activity-guided fractionation of polar e

293 Cell migration following wounding was decreased when PP5 expression was decreased

294 ellular origin, lineage infidelity occurs in wounding when stress-responsive enhancers become activat

295 e capable of fusing with lysosomes following wounding which may contribute to formation of large woun

296 kin is down-regulated in favor of FSTL1 upon wounding, which enhances keratinocyte migration and prom

297 e coating remains intact even after multiple wounding, while cell debris is simultaneously removed us

298 wounding in zebrafish, we show that repeated wounding with subsequent inflammation leads to a greater

299 ions were used as a model of corneal stromal wounding, with markers of corneal fibrosis and opacity s

300 The authors therefore hypothesized that wounding would downregulate PTEN and that this downregul