ライフサイエンスコーパス: xanthosine

1 a mostly cytosolic pathway via guanosine and xanthosine.

2 the other is more active toward uridine and xanthosine.

3 The reaction products xanthosine 3r and oxanosine 4r were separated by HPLC an

4 idation of inosine 5' monophosphate (IMP) to xanthosine 5' monophosphate, the rate-limiting step in t

5 n altered nucleotide specificity from GTP to xanthosine 5' triphosphate.

6 e 5'-(beta, gamma-methylene)triphosphate and xanthosine 5'-(beta, gamma-imido)triphosphate bound to t

7 e 5'-(beta, gamma-methylene)triphosphate and xanthosine 5'-(beta, gamma-imido)triphosphate, respectiv

8 The results indicate that xanthosine 5'-(beta, gamma-methylene)triphosphate and xa

9 onic acid and imidodiphosphonic acid to give xanthosine 5'-(beta, gamma-methylene)triphosphate and xa

10 cies, whereas xanthosine 5'-triphosphate and xanthosine 5'-[beta,gamma-imido]triphosphate were more p

11 idation of inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP) and the reduction of N

12 idation of inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP) catalyzed by IMP dehyd

13 version of inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP) is the committed and r

14 H converts inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP) with concomitant conve

15 ne-guanine phosphoribosyltransferase (HGPRT)-xanthosine 5'-monophosphate (XMP)-pyrophosphate-Mg(2+) t

16 parison of these structures with that of the xanthosine 5'-monophosphate (XMP)-pyrophosphate-Mg(2+) t

17 inosine 5'-monophosphate (IMP), and product, xanthosine 5'-monophosphate (XMP).

18 xidation of inosine 5-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP).

19 The N-methylimidazolide of xanthosine 5'-monophosphate reacted rapidly with methyle

20 ing pocket that was identified from previous xanthosine 5'-monophosphate structures.

21 DH) catalyzes the NAD-dependent synthesis of xanthosine 5'-monophosphate which is the rate-limiting s

22 IMPDH converts IMP to xanthosine 5'-monophosphate with concomitant conversion

23 investigation were the imidazolides of UMP, xanthosine 5'-monophosphate, the bis-monophosphates of t

24 amine serves as a substrate and intercepts a xanthosine 5'-monophosphate- (XMP-) adenylate intermedia

25 lar to that of the IMPCH feedback inhibitor, xanthosine 5'-monophosphate.

26 hen NAD; the product NADH is released before xanthosine 5'-monophosphate.

27 ive site to Asn (D251N), converting Ffh to a xanthosine 5'-triphosphate (XTP)-specific protein as has

28 different purine nucleotides [GTP, ITP, and xanthosine 5'-triphosphate (XTP)] on receptor/G protein

29 )-L227/N295) with similar potencies, whereas xanthosine 5'-triphosphate and xanthosine 5'-[beta,gamma

30 TP activate the avian receptor but ITP, GTP, xanthosine 5'-triphosphate, and CTP were also agonists,

31 nophosphate (GMP) formation: conversion from xanthosine-5'-monophosphate (XMP) by GMP synthase (GMPS)

32 ent oxidation of inosine-5'-monophosphate to xanthosine-5'-monophosphate.

33 te signature of ratios of 3-sialyllactose to xanthosine and quinolinate to X-16397 and our previously

34 e, guanine, xanthine, guanosine, inosine, or xanthosine as the sole purine nutrient.

35 enzymatic activity on uridine-, inosine- and xanthosine-containing DNA, can cleave oxanosine-containi

36 ed turnover on cleavage of deoxyinosine- and xanthosine-containing DNA.

37 Both compounds inhibited the xanthosine-diphosphate-dependent prenylation of a mutant

38 t required addition of exogenous xanthine or xanthosine for reactivation.

39 signature of the ratio of 3-sialyllactose to xanthosine in biopsy specimen-matched urine supernatants

40 Our data show that xanthosine is exclusively generated through the deaminat

41 t it shares with natural nucleobases but not xanthosine itself, which is an acid with a pK(a) of ca.

42 zyme that catalyzes the conversion of IMP to xanthosine monophosphate (XMP) at the branch point of pu

43 oxidation of inosine monophosphate (IMP) to xanthosine monophosphate (XMP), the committed step in de

44 (LC-MS/MS) method for the quantification of xanthosine monophosphate and adenosine monophosphate (fo

45 aphic separations have been used to quantify xanthosine monophosphate, the catalytic product of the e

46 ssible sources like the dephosphorylation of xanthosine monophosphate.

47 e active sites of Bud23 and Coffea canephora xanthosine MTase, leading us to propose and validate exp

48 sine, cytidine, guanosine, uridine, inosine, xanthosine, pseudouridine, N(2)-methylguanosine, 1-methy

49 pid quantification of the 3-sialyllactose-to-xanthosine ratio in urine samples.

50 o- and disulfates derived from guanosine and xanthosine, some of which are glycosylated, bearing one

51 des (e.g. thymidine, 5'-methylthioadenosine, xanthosine), the organosulfur compound 3-mercaptopropion

52 12, and 13 can account for the formations of xanthosine, the pH dependency and the environment depend

53 inical thought disturbance, and the ratio of xanthosine to guanosine at baseline predicted degree of

54 , rdgB/yggV, deficient in a putative inosine/xanthosine triphosphatase, conserved throughout kingdoms

55 y transcriptional antiterminator, an inosine/xanthosine triphosphatase, GidA, a methyl-accepting chem

56 D125N Ran (XTP-Ran) binds specifically to xanthosine triphosphate (XTP) and has a greatly reduced

57 nding-specificity of transposase from GTP to xanthosine triphosphate (XTP).

58 e preparation of potentially nonhydrolyzable xanthosine triphosphate derivatives.

59 of the role of individual GTPases mutated to xanthosine triphosphate specificity in the background of

60 city of which had been converted from GTP to xanthosine triphosphate.

61 We identify an association between GMPS and xanthosine using single variant analysis and association

62 lly targets the purine ribosides inosine and xanthosine, while the other is more active toward uridin