ライフサイエンスコーパス: xenobiotic

1 with respect to the presence/absence of the xenobiotic.

2 t UGT8 is involved in metabolism of endo- or xenobiotics.

3 conjugation of both endogenous compounds and xenobiotics.

4 he N-methylation of endogenous and exogenous xenobiotics.

5 , catabolism, gut microbiome activities, and xenobiotics.

6 ffspring by enhancing metabolic tolerance to xenobiotics.

7 conditions on the transformation pathways of xenobiotics.

8 on of reduced glutathione (GSH) to endo- and xenobiotics.

9 the transport of endogenous metabolites and xenobiotics.

10 o pathways associated with detoxification of xenobiotics.

11 erive energy from fatty acids and to degrade xenobiotics.

12 ediate the toxic and carcinogenic effects of xenobiotics.

13 iver disease and in damage to liver by toxic xenobiotics.

14 rect, analogous to the activation of Pdr1 by xenobiotics.

15 nt genes in response to oxidative stress and xenobiotics.

16 ociated with an enhanced ability to detoxify xenobiotics.

17 nsformations that may activate or deactivate xenobiotics.

18 CCSs for a set of endogenous metabolites and xenobiotics.

19 uential, multi-organ metabolism of drugs and xenobiotics.

20 tructurally diverse endogenous compounds and xenobiotics.

21 displayed increased susceptibility to these xenobiotics.

22 is involved in the metabolism of over 50% of xenobiotics.

23 the efflux of structurally diverse drugs and xenobiotics across cell membranes, affecting drug pharma

24 in the extrusion of endogenous compounds and xenobiotics across the plasma membrane.

25 ntagonist and promising therapeutic tool.The xenobiotic-activated human pregnane X receptor (hPXR) re

26 Xenobiotic activation of the aryl hydrocarbon receptor (

27 These data suggest that xenobiotic adaptation in this specialist herbivore is th

28 nd lipocalins, also reflect the evolution of xenobiotic adaptation.

29 bsequently developed specific and remarkable xenobiotic adaptations.

30 to microbial influences on host responses to xenobiotics, adding to the growing consensus that treatm

31 venger by binding and/or hydrolyzing various xenobiotic agents and toxicants, many of which target th

32 f P450 expression in response to exposure to xenobiotic agonists of the nuclear receptors constitutiv

33 ontrol metabolism of glucose, nutrients, and xenobiotics; alterations in its activity may contribute

34 rostane receptor (CAR) is a key regulator of xenobiotic and endobiotic metabolism.

35 across tissue sections to build an image of xenobiotic and endogenous compound distribution to asses

36 ve species to chemical interactions with the xenobiotic and endogenous metabolizing (EROD and BFCOD)

37 teractions of emerging contaminants with the xenobiotic and endogenous metabolizing system of deep-se

38 androstane receptor (CAR) regulates hepatic xenobiotic and energy metabolism, as well as promotes ce

39 toxicity pathways being affected, including xenobiotic and lipid metabolism and the thyroid hormone

40 n vitro bioassays revealed the occurrence of xenobiotic and steroid-like activities, including very h

41 Associations between selected xenobiotics and antinuclear antibodies in the National H

42 Genes involved in the metabolism of xenobiotics and antioxidant mechanisms were primarily do

43 ns play important roles in detoxification of xenobiotics and during physiological and developmental p

44 nhance the detoxification and elimination of xenobiotics and endobiotics by modulating the expression

45 R) regulates the metabolism and excretion of xenobiotics and endobiotics by regulating the expression

46 nzymes responsible for hydroxylation of many xenobiotics and endogenous chemicals in living organisms

47 ular export of a chemically diverse array of xenobiotics and endogenous compounds.

48 orters to essentially detoxify and eliminate xenobiotics and endotoxins from the body.

49 naling (IIS) pathway increases resistance to xenobiotics and extends lifespan in Drosophila, and can

50 ntribution of food to the bioaccumulation of xenobiotics and hence toxicity is still an ambiguous iss

51 which has a central role in the clearance of xenobiotics and in cancer resistance to chemotherapy.

52 GST is widely studied in the metabolism of xenobiotics and is a major contributing factor in resist

53 tress generated by exposure to electrophilic xenobiotics and metabolites induces the expression of CY

54 al mechanisms involved in insect immunity to xenobiotics and pathogens as well as the mechanisms by w

55 interfere with metabolism of drugs and other xenobiotics and provides a molecular mechanism for this

56 t functions as a sensor to a wide variety of xenobiotics and regulates expression of several drug met

57 Microbial deconjugation of xenobiotics and release of aromatic moieties into the co

58 dependent transcription factor that binds to xenobiotics and responds by regulating the expression of

59 or that mediates the biochemical response to xenobiotics and the toxic effects of a number of environ

60 Concurrent exposure to a wide variety of xenobiotics and their combined toxic effects can play a

61 d showed similar changes in their secondary, xenobiotic, and antioxidant metabolism to those determin

62 bial metabolism as it relates to bile acids, xenobiotics, and diet in the etiology and therapeutics o

63 nisms underlying salivary gland transport of xenobiotics, and most drugs are assumed to enter saliva

64 ome conditions host immunity to microbes and xenobiotics, and regulates autoimmune responses that can

65 ty, highlight the unintended consequences of xenobiotics, and suggest that attempts at personalized m

66 otic metabolism, together with resistance to xenobiotics, are frequent correlates of lifespan extensi

67 e aryl hydrocarbon receptor (AHR) recognizes xenobiotics as well as natural compounds such as tryptop

68 obtained with the Activated Sludge Model for Xenobiotics (ASM-X)) with representative measured data f

69 (WATS) model and Activated Sludge Model for Xenobiotics (ASM-X).

70 ioactivation of specific pharmaceuticals and xenobiotics bearing nucleophilic centers.

71 igh weight rabbits, and pathways related to "xenobiotics biodegradation" and "various types of N-glyc

72 we determined the thermal sensitivity of the xenobiotic biotransformation enzymes.

73 (CNS) of a wide range of neurotoxicants and xenobiotics, but also therapeutics.

74 on way of studying the environmental fate of xenobiotics, but it can be difficult to extract relevant

75 n the overrepresented pathways Metabolism of Xenobiotics by Cytochrome P450 and Butanoate and Tryptop

76 diates involved in the metabolism of various xenobiotics by cytochrome P450, as well as in chemical r

77 ins, as well as in the metabolism of various xenobiotics by cytochrome P450.

78 rganism with innate resistance toward select xenobiotics by triggering their efflux.

79 nds--endogenous metabolites, drugs and other xenobiotics--by transferring the sulfuryl moiety (SO3) f

80 Many classes of xenobiotics can significantly suppress or enhance immune

81 the reduction and oxidation of biogenic and xenobiotic carbonyls.

82 a ubiquitous DNA lesion, formed not only by xenobiotic carcinogens but also by the endogenous methyl

83 porter for CP uptake of bioactive amines and xenobiotic cations.

84 thogen P. aeruginosa and to treatment with a xenobiotic chelator, phenanthroline, in C. elegans.

85 f by-products from each production and avoid xenobiotic chemicals, we have achieved beneficial improv

86 d Escherichia coli to assimilate melamine, a xenobiotic compound containing nitrogen.

87 lthough AhR was first identified to bind the xenobiotic compound dioxin, AhR is now known to bind a v

88 ribute to defense against microorganisms and xenobiotic compounds acquired while foraging.

89 e transporters are involved in the efflux of xenobiotic compounds and are responsible for decreasing

90 Mammalian systems inactivate endobiotic and xenobiotic compounds by linking them to a glucuronic aci

91 The toxicity of many xenobiotic compounds is believed to involve oxidative in

92 ATP-Binding Cassette transporter that pumps xenobiotic compounds out of cells.

93 tion of different sets of genes by different xenobiotic compounds, in part through feed-forward activ

94 holesterol homeostasis, and the breakdown of xenobiotic compounds, including many current drugs.

95 ta have been implicated in the metabolism of xenobiotic compounds, motivating studies of microbe-driv

96 ing effective metabolism of both natural and xenobiotic compounds.

97 everal procarcinogens and detoxifies several xenobiotic compounds.

98 Benzotriazoles (BTs) are xenobiotic contaminants widely distributed in aquatic en

99 e major mitochondrial autoantigen of PBC and xenobiotic cross reactive chemicals.

100 d a distinct noncirculating tissue source of xenobiotic crossreacting antibodies.

101 TLR2 acts as a central regulator of xenobiotic defense via the multidrug transporter ABCB1/M

102 contains pathways not found in MetaCyc, for xenobiotic degradation, glycan metabolism, and metabolis

103 fs based on their variance to assess whether xenobiotic-derived substructures are among the most-vari

104 22 out of the 30 most-variant Mass2Motifs to xenobiotic-derived substructures including paracetamol/a

105 Xenobiotic detoxification and immune genes are similarly

106 It functions in xenobiotic detoxification by regulating the expression o

107 ntestine, which results in activation of the xenobiotic detoxification enzyme flavin-containing monoo

108 role for CPL4 as a negative regulator of the xenobiotic detoxification pathway.

109 liver plays a pivotal role in metabolism and xenobiotic detoxification, processes that must be partic

110 shifts in the expression of genes related to xenobiotic detoxification, stress resistance, and insuli

111 ion in stress responses, defense systems, or xenobiotic detoxification.

112 t affected, this effect has implications for xenobiotic detoxification.

113 ly increased resistance of Drosophila to the xenobiotic dichlordiphenyltrichlorethan (DDT), by artifi

114 ds, fatty acids, food, smoke, additives, and xenobiotic drugs.

115 Exposure to a xenobiotic during early development induced persistent f

116 est that larvae may be less able to detoxify xenobiotics encountered in diet than adults, and these f

117 he cell to carry out conjugation without the xenobiotic entering into the interior of the cell.

118 concentrations of representative natural and xenobiotic estrogens for 48 h were determined by microar

119 To test the hypothesis that xenobiotic exposure at environmentally relevant concentr

120 e) and increases population sensitivity to a xenobiotic exposure due to size-dependent toxicity (e.g.

121 effects of nanomaterials, and the impact of xenobiotic exposure on the developing immune system.

122 rturbations remains unclear, but may include xenobiotic exposure, natural senescence, and/or interind

123 cotinic receptor antagonist, suggesting that xenobiotic exposure, rather than nicotinic receptor sign

124 h was previously hypothesized as a marker of xenobiotic exposure.

125 thought to play a role in protection against xenobiotic exposure.

126 data suggest that background levels of most xenobiotic exposures typical in the U.S. population are

127 detecting biological responses to low-level xenobiotic exposures, these data can aid the classificat

128 protecting the brain parenchyma by efflux of xenobiotics from capillary endothelial cells at the bloo

129 hesis as well as clearing waste products and xenobiotics from the fetal circulation.

130 Although the detoxification mechanisms for xenobiotics have been extensively studied in mammalian c

131 l, we quantified the amount of a fluorinated xenobiotic (heptafluorobutyric acid, HFBA) in three diff

132 e; how our microbiome mediates metabolism of xenobiotics; how the microbiota contribute to immunity a

133 y of the organism are necessary to elucidate xenobiotic impacts along the effect cascade.

134 the relative contribution of food-associated xenobiotics in bioaccumulation depends on species, subst

135 m-specific contribution to the metabolism of xenobiotics in complex biological samples has not been p

136 y and contamination of various compounds and xenobiotics in environmental biology and microbial ecolo

137 me P450 enzymes, the primary metabolizers of xenobiotics in humans.

138 uced a broad protective response to multiple xenobiotics in male offspring.

139 of all clinically prescribed drugs and other xenobiotics in the human body.

140 -time intracellular redox changes induced by xenobiotics in toxicological studies.

141 ing contamination of reclaimed wastewater by xenobiotics including pharmaceuticals.

142 into PXR-mediated cellular responses toward xenobiotics including therapeutics.

143 g the absorption and disposition of consumed xenobiotics including various drugs and dietary phytoche

144 ngaged in the biotransformation of endo- and xenobiotics, including >50% of clinically relevant drugs

145 ne, UDP-glucose, and UDP-xylose to conjugate xenobiotics, including drugs and endobiotics such as met

146 s that are responsible for the metabolism of xenobiotics, including drugs such as irinotecan and osel

147 ms that influence our health by metabolizing xenobiotics, including host-targeted drugs and antibioti

148 endobiotic estradiol-17-glucuronide and the xenobiotic indomethacin-acyl-glucuronide are found to ex

149 was the most appropriate model for detecting xenobiotic-induced metabolomic perturbations.

150 assessment of mechanistic events involved in xenobiotic-induced oxidative stress is not easily achiev

151 eously limits the passage of drugs and other xenobiotics into the body.

152 ricting the entry of endogenous compounds or xenobiotics into tissues and it plays important roles in

153 The fundamental role of AOX in metabolizing xenobiotics is also due to the attempt of medicinal chem

154 Thyroid disruption by xenobiotics is associated with a broad spectrum of sever

155 ot infect animals and the metabolism of many xenobiotics is different between human beings and animal

156 on of the aryl hydrocarbon receptor (AHR) by xenobiotics is known to affect epidermal differentiation

157 ing amino acids, nucleotides, carbohydrates, xenobiotics, lipids, and other classes.

158 BCRP in limiting fetal exposure to drugs and xenobiotics, long-term use of these medications may affe

159 Many drugs and other xenobiotics may reach systemic concentrations where they

160 c agents and for eliminating drugs and other xenobiotics, may be involved in obesity.

161 cant changes in expression of genes encoding xenobiotic metabolism (cyp4) and moulting (cut).

162 ve health-relevant endpoints were related to xenobiotic metabolism (pregnane X and aryl hydrocarbon r

163 eceptor-controlled cholesterol/bile acid and xenobiotic metabolism among the top deregulated pathways

164 These genes are largely involved in xenobiotic metabolism and antioxidative and anti-inflamm

165 r (AhR) is a nuclear receptor that regulates xenobiotic metabolism and detoxification.

166 Additional research suggests xenobiotic metabolism and subcellular components, such a

167 gut microbes, genes, and enzymes involved in xenobiotic metabolism are poorly understood.

168 rs, the function of PXR in the regulation of xenobiotic metabolism has been extensively studied, and

169 t in recent years, since its contribution in xenobiotic metabolism has not always been identified bef

170 the distinct evolution of genes involved in xenobiotic metabolism in mites.

171 hich acts as a xenobiotic sensor to regulate xenobiotic metabolism in the liver and intestine.

172 l be important to determine whether enhanced xenobiotic metabolism is also a correlated, rather than

173 The chemistry of gut microbial xenobiotic metabolism is often distinct from that of hos

174 We investigated the xenobiotic metabolism of the red-blooded Gobionotothen g

175 ng on the association of starch, sucrose and xenobiotic metabolism pathway with longevity is consiste

176 analyses found a significant enrichment for "xenobiotic metabolism signaling" and "PXR/RXR activation

177 , a molecular understanding of gut microbial xenobiotic metabolism will guide personalized medicine a

178 (body weight, protein, chitobiase, catalase, xenobiotic metabolism, and acetylcholinesterase) were me

179 ne X receptor (PXR) is a master regulator of xenobiotic metabolism, and its activity is critical towa

180 tant toxicity pathways, such as induction of xenobiotic metabolism, and some integrative indicators d

181 ne receptor (CAR) plays an important role in xenobiotic metabolism, energy homeostasis, and cell prol

182 tration, and significant gene alterations in xenobiotic metabolism, including a decrease in ABCB1/mul

183 several stress related mRNAs and proteins of xenobiotic metabolism, oxidative stress, DNA damage, and

184 ith daily alterations in lipid, glucose, and xenobiotic metabolism, protein turnover, and redox balan

185 the toxicity pathways including induction of xenobiotic metabolism, specific and reactive modes of to

186 Increased expression of genes involved in xenobiotic metabolism, together with resistance to xenob

187 tor of the cellular antioxidant response and xenobiotic metabolism.

188 tor (PXR) plays a central role in regulating xenobiotic metabolism.

189 tion enzymes, including some associated with xenobiotic metabolism.

190 l molecular link between innate immunity and xenobiotic metabolism.

191 erimental animal models poorly predict human xenobiotic metabolism.

192 indicates four pathways (starch, sucrose and xenobiotic metabolism; immune response and inflammation;

193 l gene groups, with carbohydrate, lipid, and xenobiotics metabolism belonging to the EPE and MPE clus

194 ent were enriched with genes associated with xenobiotics metabolism.

195 , the AhR has been studied as a regulator of xenobiotic metabolizing enzyme genes, notably cytochrome

196 Drug and xenobiotic metabolizing enzymes (DXME) play important ro

197 Moreover, these polyphenols up-regulated xenobiotic metabolizing enzymes UGT1A10 and CYP1A1, enha

198 nooxygenases (FMOs) are primarily studied as xenobiotic metabolizing enzymes with a prominent role in

199 m and defending themselves via an arsenal of xenobiotic metabolizing enzymes.

200 ed A287P or WT POR, as were those of several xenobiotic-metabolizing cytochromes P450, indicating tha

201 Human cytochrome P450 3A4 (CYP3A4) is a key xenobiotic-metabolizing enzyme that oxidizes and clears

202 and vitamin D receptor, which regulate major xenobiotic-metabolizing enzymes and efflux transporters.

203 mine N-acetyltransferases (NATs), a class of xenobiotic-metabolizing enzymes, catalyze the acetylatio

204 that is only revealed upon treatment with a xenobiotic molecule.

205 ts suggest that pregnane X receptor (PXR), a xenobiotic nuclear receptor important for defense agains

206 l liver together with Tcf-4, Hnf-4alpha, and xenobiotic nuclear receptors.

207 ily targeted by beta-catenin, partly through xenobiotic nuclear receptors.

208 Resistance to xenobiotic nucleosides used to treat acute myeloid leuke

209 clearing potentially harmful endobiotic and xenobiotic OAs from the eye.

210 t" study demonstrates that human exposure to xenobiotics occurs through ingestion of reclaimed wastew

211 g., peak height) to decide whether a certain xenobiotic of interest (XOI) is present/absent, yielding

212 Effects of some xenobiotics on aquatic organisms might not be caused dir

213 imed to delineate effects of food intake and xenobiotics on oxidative biomarkers in Daphnia magna.

214 Supplying essential growth nutrients through xenobiotic or ecologically rare chemicals provides micro

215 ime extremely potent activators of the other xenobiotic or hormonal receptors, namely PXR, AHR, and v

216 ed sugar water feeders amended with either a xenobiotic or solvent only (control).

217 es boosting overall metabolic elimination of xenobiotic or toxic compounds.

218 ath caused by serum deprivation, toxicity of xenobiotics or high concentrations of extracellular aden

219 More of these 17 metabolites were of xenobiotic origin than would be expected by chance (9 of

220 adaptive response of the liver to bile acids/xenobiotic overload.

221 rance, and transformational toxicity of most xenobiotics owing to its abundance in cytochrome P450 (C

222 ption factors and repressors in responses to xenobiotics, oxidants, heat, hypoxia, DNA damage, and in

223 s are encompassed in the broad definition of xenobiotic particles.

224 is now shifting from the role of AhR in the xenobiotic pathway toward its mode of action in response

225 The lysolipid and food and plant xenobiotic pathways were most strongly associated with d

226 -glycoprotein and modulate toxicity of other xenobiotics present in complex environmental samples.

227 Study of xenobiotics present in fruit peel by exposing it (withou

228 ct the conceptus from exposure to toxins and xenobiotics present in the maternal circulation.

229 aine, accompanied by hepatic upregulation of xenobiotic processing genes, and enhanced drug clearance

230 The xenobiotic rapamycin is a potent inhibitor of the yeast

231 vation of either beta-catenin or the nuclear xenobiotic receptor CAR.

232 CINPA1 1) is a specific xenobiotic receptor inhibitor and has no cytotoxic effec

233 s constituting the first class of potent pan-xenobiotic receptor ligands that can serve as potential

234 The human nuclear xenobiotic receptor PXR recognizes a range of potentiall

235 a nuclear receptor considered to be a master xenobiotic receptor that coordinately regulates the expr

236 ptor (CAR), was initially characterized as a xenobiotic receptor that regulates drug metabolism.

237 Pregnane X receptor (PXR) is a xenobiotic receptor that regulates the detoxification an

238 receptor, was originally characterized as a xenobiotic receptor that senses xenotoxicants.

239 arbon (AHR) receptors, it is referred to as "xenobiotic receptor".

240 ter screening assay with an array of nuclear xenobiotic receptors (XenoRs), we found that TCS activat

241 ounterproductive in tissues where both these xenobiotic receptors are present and active.

242 ry rate </=0.10, only 4-ethylphenylsufate, a xenobiotic related to benzoate metabolism, was significa

243 any up-regulation of genes involved in multi-xenobiotic resistance (MXR) or detoxification (phases I

244 Thus, in Drosophila IIS mutants, increased xenobiotic resistance and enhanced longevity are not cau

245 6, as an essential mediator of the increased xenobiotic resistance of IIS mutant flies.

246 d long-lived in the absence of DHR96 and the xenobiotic resistance that it conferred.

247 iction increased lifespan without increasing xenobiotic resistance, confirming that the two traits ca

248 recognition sequence called the nonconsensus xenobiotic response element (NC-XRE).

249 AhR activity depends on its binding to the xenobiotic response element (XRE) in partnership with th

250 ding to the newly characterized nonconsensus xenobiotic response element, in conjunction with the tum

251 ereas dKeap1 inhibited CncC binding at other xenobiotic response gene loci and suppressed their trans

252 Exposure to 2,5-DCB induced multiple xenobiotic response genes, such as cytochrome P-450 and

253 ese loci, whereas CncC alone activated other xenobiotic response genes.

254 nd stimulated expression of predicted target xenobiotic response-related genes AHRR (P = 1.13 x 10-62

255 ed transcript levels of a suite of herbicide/xenobiotic-responsive genes and improved herbicide toler

256 Xenobiotic-responsive genes were found across multiple b

257 How honey bees assess xenobiotic risk to nestmates as they forage is poorly un

258 ath of an individual, targeted or untargeted xenobiotic screening of post-mortem samples is normally

259 XR plays many other roles in addition to its xenobiotic-sensing function.

260 The pregnane X receptor (PXR, NR1I2) is a xenobiotic-sensing nuclear receptor that modulates the m

261 the NR1I nuclear receptor family, acts as a xenobiotic sensor and a paramount transcriptional regula

262 xtensively studied, and the role of PXR as a xenobiotic sensor has been well established.

263 r pregnane X receptor (PXR), which acts as a xenobiotic sensor to regulate xenobiotic metabolism in t

264 r (PXR, NR1I2), initially characterized as a xenobiotic sensor, has been functionally linked to the r

265 ve androstane receptor (CAR, NR1i3), a known xenobiotic sensor, has recently been recognized as a nov

266 ated intestinal barrier function through the xenobiotic sensor, pregnane X receptor (PXR).

267 ng pathways beyond its established role as a xenobiotic sensor.

268 ptor (CAR) and pregnane X receptor (PXR) are xenobiotic sensors that enhance the detoxification and e

269 Short-term exposure to a panel of xenobiotics significantly affected the physiology, struc

270 rbon receptor (AHR), a conserved detector of xenobiotic small molecules.

271 the mammalian metabolism of amine-containing xenobiotics, some N-acylation reactions were not previou

272 A receptor DOP-1 activates the expression of xenobiotic stress response genes involved in pathogenic

273 ignal to frontline epithelia to activate the xenobiotic stress response so as to maintain proteostasi

274 ession of hepatocellular carcinoma driven by xenobiotic stress.

275 ation of endogenous neurotransmitters and of xenobiotic substances and hormones incorporating catecho

276 h Mates interact with both physiological and xenobiotic substances but also substantially differ with

277 of a healthy, smoking male subject, several xenobiotic substances such as benzene, toluene, styrene,

278 he toxicokinetics and tissue distribution of xenobiotic substances, such as perfluorooctanoic acid (P

279 body, protecting against the penetration of xenobiotic substances.

280 ld for its role in mediating the toxicity of xenobiotics such as 2,3,7,8-tetrachlorodibenzo-p-dioxin

281 with C. albicans nomenclature) could efflux xenobiotics such as berberine, rhodamine 123, and paraqu

282 Xenobiotics such as the neonicotinoid pesticide, imidacl

283 hypothesized that glucuronide conjugates of xenobiotics, such as the anticancer drug sorafenib, can

284 e I IFN and TLR trafficking and signaling in xenobiotic systemic mercury-induced autoimmunity (HgIA).

285 llen, or propolis, as well as five synthetic xenobiotics that frequently contaminate hives-two herbic

286 bition, but also crossreactive with chemical xenobiotics that share molecular homology with the inner

287 rders of magnitude for analytes ranging from xenobiotics to endogenous lipids, and facilitated the re

288 ology by taking into account the spectrum of xenobiotics to which bees are exposed.

289 Embryonic development is highly sensitive to xenobiotic toxicity and in utero exposure to environment

290 l hydrocarbon receptor (AhR), a regulator of xenobiotic toxicity, is a member of the eukaryotic Per-A

291 , a transcription factor known for mediating xenobiotic toxicity, is expressed in B cells, which are

292 ons to the metabolism of ingested compounds (xenobiotics), transforming hundreds of dietary component

293 eractions resulting from drug, metabolite or xenobiotic transport between organs are key components o

294 4(+) T effector (Teff) cells upregulated the xenobiotic transporter, Mdr1, in the ileum to maintain h

295 Cyclophosphamide is one such xenobiotic used in cancer therapies.

296 s confer cellular protection against diverse xenobiotics via not only binding, but also catalysis.

297 increases the detoxification of postprandial xenobiotics via the GST action mediated hepatic GSH conj

298 lved in the phenomenon of resistance against xenobiotics, which are clinically relevant in bacteria,

299 iably obtain in vitro intrinsic clearance of xenobiotics, which provides support for the application

300 assessments of cells undergoing exposure to xenobiotics with strong oxidizing properties.