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1 regulate the expression of genes involved in xenobiotic metabolism.
2 y glucosides and may play a critical role in xenobiotic metabolism.
3 aling pathways, transcription regulators, or xenobiotic metabolism.
4 s of SXR/PXR expression that are critical in xenobiotic metabolism.
5 ave an important role in thyroid hormone and xenobiotic metabolism.
6 compounds that regulate mammalian enzymes of xenobiotic metabolism.
7 renal cortex and its relationship to adrenal xenobiotic metabolism.
8 est a major role for this isozyme in adrenal xenobiotic metabolism.
9 s, coinciding with the major site of adrenal xenobiotic metabolism.
10 tor of the cellular antioxidant response and xenobiotic metabolism.
11 tor (PXR) plays a central role in regulating xenobiotic metabolism.
12 tion enzymes, including some associated with xenobiotic metabolism.
13 l molecular link between innate immunity and xenobiotic metabolism.
14 ptor that functions as a master regulator of xenobiotic metabolism.
15 eceptor (CAR) is a central regulator of drug/xenobiotic metabolism.
16 mechanisms associated with the silencing of xenobiotic metabolism.
17 regulates enzymes involved in endobiotic and xenobiotic metabolism.
18 ting the toxicological effects of dioxin and xenobiotic metabolism.
19 mic reticulum (ER)-proteins, responsible for xenobiotic metabolism.
20 were found for genes related to estrogen or xenobiotic metabolism.
21 ic enzyme with an important role in drug and xenobiotic metabolism.
22 iosynthesis, steroid hormone metabolism, and xenobiotic metabolism.
23 tion factors controlling pathways modulating xenobiotic metabolism.
24 AhR is traditionally associated with xenobiotic metabolism.
25 important implications for both hormone and xenobiotic metabolism.
26 as specific to the group of NRs that control xenobiotic metabolism.
27 erimental animal models poorly predict human xenobiotic metabolism.
28 molecular mechanisms lead to enhancements in xenobiotic metabolism.
29 teins that play a prominent role in drug and xenobiotic metabolism.
30 ent were enriched with genes associated with xenobiotics metabolism.
31 uctural relationships among these enzymes of xenobiotic metabolism, a structure-based evolutionary se
32 eceptor-controlled cholesterol/bile acid and xenobiotic metabolism among the top deregulated pathways
37 commonly studied for its role in regulating xenobiotic metabolism and dioxin toxicity, a development
41 have previously reported functions involving xenobiotic metabolism and protein-folding machinery of t
43 ation of multiple cellular pathways, such as xenobiotic metabolism and Th17 cell differentiation.
44 atic cytochrome P450 (CYP) genes involved in xenobiotic metabolism and that exposure to xenobiotic ch
47 t CYP6 family (both of which are involved in xenobiotic metabolism) and to the insect CYP9 family (of
48 (body weight, protein, chitobiase, catalase, xenobiotic metabolism, and acetylcholinesterase) were me
49 ioxin (dioxin) hepatotoxicity, regulation of xenobiotic metabolism, and hepatovascular development.
50 ne X receptor (PXR) is a master regulator of xenobiotic metabolism, and its activity is critical towa
52 tant toxicity pathways, such as induction of xenobiotic metabolism, and some integrative indicators d
53 nal substrate and energy used to up-regulate xenobiotic metabolism, and therefore not available for p
54 t absorption, mucosal barrier fortification, xenobiotic metabolism, angiogenesis, and postnatal intes
56 e cytochrome P450 (CYP) isoforms involved in xenobiotic metabolism are enzymes whose substrate select
59 egulates the expression of genes involved in xenobiotic metabolism as well as hormone, energy, and li
60 xide hydrolase (mEH) plays a central role in xenobiotic metabolism as well as mediating the sodium-de
61 l gene groups, with carbohydrate, lipid, and xenobiotics metabolism belonging to the EPE and MPE clus
62 d phase II (e.g. glutathione S-transferases) xenobiotic metabolism, bioenergetics (e.g. cytochrome ox
63 a mechanistic explanation for alteration of xenobiotic metabolism by cytokines and compounds that re
64 he constitutive androstane receptor (CAR) in xenobiotic metabolism by inducing expression of cytochro
65 ed nuclear receptor VDR regulate steroid and xenobiotic metabolism by inducing the phase I cytochrome
66 cilitate studies of the role of this gene in xenobiotic metabolism, cancer, and other human diseases.
67 factor that regulates genes involved in drug/xenobiotic metabolism, cell cycle progression, cell fate
70 P70), metal-binding (metallothionein-A), and xenobiotic metabolism (Cyp1a1) utilizing quantitative po
71 gene families with functions in steroid and xenobiotic metabolism (Cyp2d), reproduction (MUPs), and
73 d to several functional categories including xenobiotic metabolism, detoxification, disease, and stre
74 ne receptor (CAR) plays an important role in xenobiotic metabolism, energy homeostasis, and cell prol
75 ancer effects with the induction of phase II xenobiotic metabolism enzymes via activation of the Keap
77 including (i) transcriptional control of the xenobiotic metabolism genes Cyp1a1 and Cyp1b1 and (ii) i
78 rs, the function of PXR in the regulation of xenobiotic metabolism has been extensively studied, and
79 t in recent years, since its contribution in xenobiotic metabolism has not always been identified bef
80 nism-based inactivation of P450s involved in xenobiotic metabolism has the potential to lead to adver
81 de axonal transport, vesicle trafficking and xenobiotic metabolism have been implicated in neurodegen
83 indicates four pathways (starch, sucrose and xenobiotic metabolism; immune response and inflammation;
87 e anticipated in light of current models for xenobiotic metabolism in plants, evidence for unsuspecte
88 to an enzyme functioning in both primary and xenobiotic metabolism in prokaryotes and eukaryotes.
93 used as a pan-antagonist of NRs involved in xenobiotic metabolism in vivo, which may lead to novel s
95 tration, and significant gene alterations in xenobiotic metabolism, including a decrease in ABCB1/mul
96 inct sets of genes involved in all phases of xenobiotic metabolism, including oxidative metabolism, c
97 link between activation of AhR signaling and xenobiotic metabolism, inhibitors of HDAC6 may alter dru
98 l be important to determine whether enhanced xenobiotic metabolism is also a correlated, rather than
99 liver proteins involved in reproduction and xenobiotic metabolism is induced at puberty by sex-speci
101 ulation of the genes relevant to steroid and xenobiotic metabolism, is likely to have clinical signif
102 Studies of vitamin E metabolism suggest that xenobiotic metabolism may not only regulate vitamin E co
103 ibrosis, and reduced capacity for apoptosis, xenobiotic metabolism, normal cell-cycling, and DNA repl
105 ation to therapy is achieved by upregulating xenobiotic metabolism or a redundant signaling pathway,
106 several stress related mRNAs and proteins of xenobiotic metabolism, oxidative stress, DNA damage, and
107 ng on the association of starch, sucrose and xenobiotic metabolism pathway with longevity is consiste
108 ve health-relevant endpoints were related to xenobiotic metabolism (pregnane X and aryl hydrocarbon r
110 ith daily alterations in lipid, glucose, and xenobiotic metabolism, protein turnover, and redox balan
112 analyses found a significant enrichment for "xenobiotic metabolism signaling" and "PXR/RXR activation
113 the toxicity pathways including induction of xenobiotic metabolism, specific and reactive modes of to
114 is a major enzymatic determinant of drug and xenobiotic metabolism that demonstrates remarkable subst
115 the emerging importance of human P450 2B6 in xenobiotic metabolism, thorough biochemical and biophysi
116 function as a xenobiotic sensor to regulate xenobiotic metabolism through selective transcription of
117 such as virulence, antibiotic resistance and xenobiotic metabolism to spread through the human microb
118 Increased expression of genes involved in xenobiotic metabolism, together with resistance to xenob
119 ear receptor pathway would influence steroid/xenobiotic metabolism using dehydroepiandrosterone sulfo
120 a xenobiotic sensor to coordinately regulate xenobiotic metabolism via transcriptional regulation of
122 , a molecular understanding of gut microbial xenobiotic metabolism will guide personalized medicine a
123 erences in lipid, drug, steroid hormone, and xenobiotic metabolism, with distinct responses of males
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