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1 catabolism of the released l-arabinose and d-xylose.
2 9), and Arg(226), and the hydroxyl groups of xylose.
3 AT1, towards both alpha- and beta-anomers of xylose.
4 riched in transporters that confer growth on xylose.
5 DH were not affected at all by 5mM (75mg/dL) xylose.
6 y affected transport of both D-glucose and D-xylose.
7 ially glycated by incubation with glucose or xylose.
8 -D-glucuronic acid to UDP-D-apiose and UDP-D-xylose.
9 the most stable chair conformation of UDP-D-xylose.
10 esized in 7-8 steps from easily accessible D-xylose.
11 arboxylation of UDP-D-glucuronic acid to UDP-xylose.
12 onic acid (UDP-GalA), UDP-arabinose, and UDP-xylose.
13 cellulosic biomass materials are glucose and xylose.
14 ne for cleavage to xylo-oligosaccharides and xylose.
15 , rhamnose, glucose, fructose, galactose and xylose.
16 odimers has been achieved from inexpensive d-xylose.
17 es cerevisiae cultures that are catabolizing xylose.
18 ulose, l-rhamnose, 3-O-methyl-d-glucose, and xylose.
19 ructure that links a phosphotrisaccharide to xylose.
20 hanol with a yield of about 0.46 g ethanol/g xylose.
22 nolicus produced high current densities from xylose (5.8 +/- 2.4 A m(-2)), glucose (4.3 +/- 1.9 A m(-
23 opment of biocatalysts capable of fermenting xylose, a five-carbon sugar abundant in lignocellulosic
24 exhibited a long lag time when metabolizing xylose above 10 g/l as a sole carbon source, defined her
25 r(147) as catalytic proton donor, yields UDP-xylose adopting the relaxed (4)C(1) chair conformation (
27 plexes of GlyA1 with glucose, galactose, and xylose allowed picturing the catalytic pocket and illust
28 ynthetic acceptor containing an alpha-linked xylose alone, but requires the presence of the underlyin
29 at Gal2-N376F had the highest affinity for D-xylose, along with a moderate transport velocity, and ha
32 ion of the polysaccharide repeating unit [-3-xylose-alpha1,3-glucuronic acid-beta1-]n by like-acetylg
35 MYB46 resulted in a significant increase in xylose and a small increase in lignin content based on a
36 an maturation to complex forms (e.g. beta1,2 xylose and alpha1,3 fucose) can render the product immun
46 been hampered by inefficient fermentation of xylose and the toxicity of acetic acid, which constitute
51 EKDEL were complex N-glycans (i.e. contained xylose and/or fucose) (88 %), whereas complex N-glycans
52 f 40 to 50 kDa and is composed of galactose, xylose, and five distinct partially O-methylated galacto
53 a strain is comprised of glucose, galactose, xylose, and four partially O-methylated galactose residu
54 f the transported sugars, including glucose, xylose, and glucosamine, and this substrate-induced expr
55 f the wheat bran was dominated by arabinose, xylose, and glucose, whereas mannose and galactose were
58 ructures (in complex with a substrate mimic, xylose, and xylobiose), the residues that tune the uniqu
59 d mediated reduction of ribose-, arabinose-, xylose-, and lyxose-derived methyl and phenyl ketofurano
63 abolism genes, many of which are involved in xylose, arabinose, cellobiose, and hemicellulose metabol
64 isiae strain to show significant growth with xylose as the sole carbon source, as well as partial co-
68 A2 from Col-0 is highly selective toward UDP-xylose as the sugar donor, and the isoform from C24 can
69 abled complete and efficient fermentation of xylose as well as a mixture of glucose and xylose by the
70 omprising the optimization of a heterologous xylose-assimilating pathway and evolutionary engineering
71 XYL1, XYL2, and XYL3 genes constituting the xylose-assimilating pathway increased ethanol yields and
72 ficiency (CE) varied by electron donor, with xylose at 34.8% +/- 0.7%, glucose at 65.3% +/- 1.0%, and
76 cular, hydrogen bonding between Asn(462) and xylose at the nonreducing end subsite +2 was important f
78 biologically relevant pyranose sugars: beta-xylose, beta-mannose, alpha-glucose, beta-glucose, and b
82 rom C24 can utilize both UDP-glucose and UDP-xylose but with a higher affinity to the glucose donor.
84 ity to their DNA binding sites, leading to a xylose catabolic activation independent of catabolite re
85 mutation in a transcriptional activator for xylose catabolic operons, either CRP or XylR, and these
86 in which glycogen synthesis is blocked, and xylose catabolism enabled through the introduction of xy
87 r versions should prove valuable for glucose-xylose cofermentation in lignocellulosic hydrolysates by
89 how any positive bias at a therapeutic level xylose concentration on the signal for a glucose sample.
90 hydrate-binding modules (CBMs) that binds to xylose-configured oligosaccharide/polysaccharide ligands
91 of the genes required for l-arabinose and d-xylose consumption is regulated by the sugar-responsive
93 ing pathway increased ethanol yields and the xylose consumption rates from a mixture of glucose and x
94 ene as a genomic change contributing to high xylose consumption, a trait important for lignocellulosi
99 d-(+)-raffinose, sucrose, d-trehalose, d-(+)-xylose, d-fructose, 1-thio-beta-d-glucose sodium salt, d
100 more active against substrates in which the xylose decorated with GlcA/MeGlcA is flanked by one or m
104 n of cysteine in the presence of fructose or xylose did not appreciably increase their production.
105 ies confirmed that a glucuronic acid beta1,4-xylose disaccharide synthesized by B4GAT1 acts as an acc
107 umed 50 g oral glucose solution mixed with d-xylose during fixed hyperglycemia at 8 and 10.5 mmol/L,
109 redox balancing strategy to enable efficient xylose fermentation and simultaneous in situ detoxificat
110 achieved industrial viability due largely to xylose fermentation being prohibitively slower than that
113 ill enable future efforts aimed at improving xylose fermentation to prioritize functional regulators
117 ch exhibited a shorter lag time and improved xylose-fermenting capabilities than the parental strain.
119 mmercial and laboratory strains (including a xylose-fermenting strain) under industrial-like conditio
120 Saccharomyces cerevisiae strains has yielded xylose-fermenting strains, but these strains have not ye
122 or possibly even enabling the development of xylose-fermenting yeasts that are not genetically modifi
123 is involved in the cleavage of the beta-1,2-xylose, followed by the alpha-mannosidase NixJ (GH125),
125 o be involved in the utilization of glucose, xylose, fucose, and arabinose, which are also substrates
127 f mutant alleles, a tight proportionality of xylose, galacturonic acid, and rhamnose was evidenced, e
129 to produce current from four electron donors-xylose, glucose, cellobiose, and acetate-with a fixed an
130 the mixture contained a negligible amount of xylose, having xylobiose, xylotriose and xylotetraose as
131 lting in strains with a 2.7-fold increase in xylose import rates, a 4-fold improvement in xylose inte
135 witch to the metabolism of l-arabinose and d-xylose in the absence of its preferred carbon source, gl
136 ed that the Araf decoration linked O3 to the xylose in the active site is located in the pocket (-2*
137 f uuat1 mutants had less GalA, rhamnose, and xylose in the soluble mucilage, and the distal cell wall
138 pectively, were produced from cellobiose and xylose in unsterilized seawater and algal-contaminated w
139 zyme activity after prolonged incubation was xylose indicating the presence of xylanase; however, a s
143 xylose import rates, a 4-fold improvement in xylose integration into central carbon metabolism, or a
145 in this process, the molecular transport of xylose into the cell, can serve as a significant flux bo
149 fficiently use glucose, their ability to use xylose is often repressed in the presence of glucose.
151 different sugars, including L-glucose and D-xylose, is described in this issue (Meinert et al., ), p
154 rried shared mutations: amplification of the xylose isomerase gene and inactivation of ISU1, a gene e
155 c library to identify multiple copies of the xylose isomerase gene as a genomic change contributing t
156 S12 strain was obtained by introducing the D-xylose isomerase pathway from Escherichia coli, followed
158 ty 20 member-B), which is a newly identified xylose kinase essential for glycosaminoglycan (GAG) form
159 neuraminic acid), 'all-or-none' responses (d-xylose, l-rhamnose) and complex combinations thereof (l-
160 total monosaccharide (glucose, arabinose and xylose) levels in the glycosides were determined after a
161 and 25 enteric isolates grown on blood agar, xylose lysine deoxycholate agar (XLD), Hektoen enteric a
164 se, galactose, arabinose, glucose, rhamnose, xylose, mannose, fructose and ribose) plus inositol as i
165 tose, arabinose, glucose, sucrose, rhamnose, xylose, mannose, fructose, and ribose were quantified in
167 ore, the competitive pathway responsible for xylose metabolism in E. coli was blocked by disrupting t
168 antially as compared to the parental strain, xylose metabolism was interrupted by accumulated acetate
169 inducible genes for L. lactis growth in ATL, xylose metabolism was targeted for gene knockout mutagen
170 e of such strains will shed further light on xylose metabolism, suggesting additional engineering app
173 i D-lactate producer TG114, 94% of a glucose-xylose mixture (50 gL(-1) each) was used in mineral salt
174 production yield of 0.35 g/g from a glucose/xylose mixture, which is significantly higher than repor
175 tage glycosidation reaction to introduce the xylose moiety and a lithiation-borylation reaction to at
176 conformational changes, whereas its extended xylose moiety forms hydrophobic interactions with a Tyr
178 cture, the nucleophile O4 oxygen atom of the xylose molecule is found in close proximity to the C1 an
180 ignocellulosic biomass hydrolysates, such as xylose, must be improved before yeast can serve as an ef
182 1 or SSK2 improved the ability to metabolize xylose of yeast cells without adaptive evolution, sugges
184 cally, a 5 wt% aldose (for example, glucose, xylose or arabinose) solution with a 4:1 aldose:sodium t
186 esponsible genes: one locus contains a known xylose-pathway gene, a novel homolog of the aldo-keto re
187 ntly solved crystallographic models of the D-xylose permease XylE from Escherichia coli and GlcP from
188 tion is impaired by loss of Fam20B-dependent xylose phosphorylation and reveal a previously unappreci
190 the wall is glucuronoxylan, a beta1,4-linked xylose polysaccharide that is decorated with alpha-linke
191 support the importance of the cytosolic UDP-xylose pool and UDP-xylose transporters in cell wall bio
192 indings suggest that the binding affinity of xylose ramifications on RG-I to a cellulose scaffold is
198 oxylanase activities and higher arabinose-to-xylose ratios of WU-AX than those of corresponding whole
199 accharomyces cerevisiae revealed that fungal xylose reductases act as xylodextrin reductases, produci
201 emonstrated that XynA is a rare reducing end xylose-releasing exo-oligoxylanase and not an endo-beta-
202 f efficient fermentation of pentoses such as xylose remains a key challenge in the production of etha
203 , in zebrafish embryos, the peptide-proximal xylose residue can be metabolically replaced with a chai
205 ber B (Fam20B) phosphorylates the initiating xylose residue in the proteoglycan tetrasaccharide linka
208 he xylan backbone polymer, a linear chain of xylose residues connected by beta-1,4 glycosidic linkage
210 s-alpha-xylosidase activity also transferred xylose residues from xyloglucan oligosaccharides to long
211 tructure and that the hydroxyl groups of all xylose residues in the active site are solvent exposed,
212 stituted oligosaccharides (AXOS) having 2-10 xylose residues in the main chain but no unsubstituted x
214 sts of a linear backbone of beta(1,4)-linked xylose residues substituted with alpha(1,2)-linked glucu
215 Xylans have a backbone of beta-1,4-linked xylose residues with substitutions that include alpha-(1
216 an, a beta1,4-glucan decorated with alpha1,6-xylose residues, by targeting structures common to the t
218 (where Man and Xyl represent d-mannose and d-xylose, respectively), underlying the molecular basis of
220 sults reveal that xylan is the most abundant xylose-rich component in Arabidopsis seed mucilage and i
222 ions (i.e., core alpha1,3-fucose and beta1,2-xylose) showed significantly enhanced binding to the Fcg
223 Asn(139), which interact with arabinose and xylose side chains at the -2* subsite, abrogates catalyt
224 also make hydrophobic interactions with the xylose side chains of xyloglucan, conferring the distinc
229 tial for achieving a high biomass yield on D-xylose, the aberrant HexR control appeared to underlie b
230 g xylitol, a five-carbon polyol derived from xylose, the most abundant pentose in lignocellulosic bio
234 DP-N-acetylglucosamine, UDP-glucose, and UDP-xylose to conjugate xenobiotics, including drugs and end
235 ilization, strains could efficiently convert xylose to ethanol with a yield of about 0.46 g ethanol/g
237 ward pentoses such as arabinose, ribose, and xylose to the exclusion of the expected fructose, which
241 ove the transcriptional state of cells using xylose toward that of cells producing large amounts of e
245 deduced from the crystal structure of the D-xylose transporter XylE from Escherichia coli, both resi
249 developed approach, we identified three UDP-xylose transporters in the Arabidopsis thaliana NST fami
251 t growth-based screening system for mutant D-xylose transporters that are insensitive to the presence
253 simultaneous fermentation of D-glucose and D-xylose, two primary sugars present in lignocellulosic bi
259 t hydrolyze short xylo-oligosaccharides into xylose units, thus complementing endoxylanase degradatio
260 strongly increased glucose (up to +81%) and xylose (up to +153%) release, suggesting that down-regul
262 two amino acid substitutions in XylR enhance xylose utilization and release glucose-induced repressio
264 rain, containing an established heterologous xylose utilization pathway, and imposed a laboratory evo
265 te consumption pathway and an NADH-producing xylose utilization pathway, engineered yeast converts ce
267 daptive evolution with selection for optimal xylose utilization, strains could efficiently convert xy
268 novel method to genetically characterize its xylose-utilization phenotype, using a tetraploid interme
270 und of COMPACTER was used to generate both a xylose utilizing pathway with near-highest efficiency an
276 The negligible activity of AnGDH towards xylose was also explained on the basis of a 3D structura
277 ing a novel polyphosphate xylulokinase (XK), xylose was converted into H2 and CO2 with approaching 10
279 , and once glucose was completely exhausted, xylose was used by the microorganisms, mainly related to
281 the repeats but that extension of glucose by xylose weakens stability, explained by the binding of th
285 se and hexose sugars, especially glucose and xylose, which are the most abundant sugars in cellulosic
286 li strain was constructed to produce BT from xylose, which is a major component of the lignocellulosi
288 ellent overall yield of more than 10% from d-xylose, while the heterodimer route led to UT-39 in 19 s
289 -3-enopyranosid-2-ulose) was prepared from D-xylose, while the R analogue was obtained from L-arabino
293 the simultaneous determination of arabinose, xylose, xylo-oligosaccharides (XOS), and AXOS by applyin
296 ell wall, consists of a backbone of beta-1,4-xylose (Xylp) units that are often decorated with arabin
297 henol abundance, and four for glucose and/or xylose yield, not a single QTL for aromatic abundance an
299 idazolium acetate, 90-95% glucose and 70-75% xylose yields were obtained for these samples after 72-h
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