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1 oteins associated with the GAL1-10 region in yeast.
2 sayed, 20 genes exhibited strong toxicity in yeast.
3 lization and thus phospholipid metabolism in yeast.
4 per splicing of certain pre-mRNAs in fission yeast.
5 e mitochondrial cysteine desulfurase Nfs1 in yeast.
6 ensively studied before those in mammals and yeast.
7 mitotic entry to membrane growth in budding yeast.
8 striction of the contractile ring in fission yeast.
9 igated how heat stress promotes longevity in yeast.
10 the transcriptome in the meiosis of fission yeast.
11 nal well-characterized NLSs from mammals and yeast.
12 eases in mammals and inherited phenotypes in yeast.
13 enhancing promoter directionality in budding yeast.
14 , which is even fewer than that reported for yeast.
15 work in parallel to promote Cse4 turnover in yeast.
16 were identified, confirming the work done in yeast.
17 he abundance of mRNA and reporter protein in yeast.
18 ues at 5' ends of genes that is conserved in yeast.
19 y, most show evidence for divergence in both yeasts.
20 ase maintains chromosome ends from humans to yeasts.
21 s are both frequently found in Saccharomyces yeasts.
22 While the protein composition of various yeast 60S ribosomal subunit assembly intermediates has b
23 ression output, we have conducted in budding yeast a large-scale measurement of the activity of thous
25 N(tz)AD(+) and N(tz)ADH to be substrates for yeast alcohol dehydrogenase and lactate dehydrogenase, r
26 ng programs have been extensively studied in yeast and animal systems, but much less is known about t
27 eins that support copper-dependent growth in yeast and enhance copper accumulation in Ctr1(-/-) mouse
28 acteroidetes, suggesting that utilization of yeast and fungal cell wall 1,6-beta-glucans is a widespr
30 be applied to identify sulfated proteins in yeast and human proteome microarrays, and we expect such
31 ly doubles the number of proteins within the yeast and human proteomes that can be explored as potent
32 e the enzymatic activities and structures of yeast and human U6 RNA processing enzyme Usb1, reconstit
33 yze four independently constructed IINs from yeast and humans and find a conserved structure of these
35 ast, herein we analyze Hi-C data for budding yeast and identify 200-kb scale TADs, whose boundaries a
36 and the lagging DNA strands were reported in yeast and in human cancers, but the causes of these diff
38 w that over 30% of the effectors localize to yeast and mammalian cell membranes, including a subset o
39 or directly engineering the surfaces of live yeast and mammalian cells through cell surface-initiated
42 performed comparative ribosome profiling in yeast and mice with various ribonucleases including I, A
46 with this prediction, protein aggregation in yeast and worms was observed to increase when translatio
48 iotic stresses in E. pusillum and transgenic yeast, and its stress-resistant ability was stronger tha
50 amily, Pry1, -2, and -3 (pathogen related in yeast), are encoded in the Saccharomyces cerevisiae geno
54 illations of the anaphase spindle in budding yeast, but in A. gossypii, this system is not restricted
56 e results define direct structural roles for yeast CAF-1 subunits and uncover a previously unknown cr
57 volved in the direct interaction between the yeast CAF-1 subunits, and mapped the CAF-1 domains respo
60 mimetic FUS reduces aggregation in human and yeast cell models, and can ameliorate FUS-associated cyt
68 show that upon growth at higher temperature, yeast cells relax the retention of DNA circles, which ac
69 Nitrogen replenishment of nitrogen-starved yeast cells resulted in substantial transcriptome change
70 (GET) pathway was described in mammalian and yeast cells that serve as a blueprint of TA protein inse
74 and formation of a shmoo-like morphology in yeast cells, lower pheromone doses elicit elongated cell
80 tion, we determined the crystal structure of yeast ChaC2 homologue, GCG1, at 1.34 A resolution, which
82 er transport, its heterologous expression in yeast complemented copper-specific defects observed upon
85 vulnerable to infection by the encapsulated yeast Cryptococcus neoformans Most commonly found in the
87 ontractile ring assembly in vivo.The fission yeast cytokinetic ring assembles by Search-Capture-Pull-
88 se1sbd successfully heterodimerized with the yeast cytosolic Hsp70s Ssa and Ssb and promoted normal g
92 1 R585Q and E152K to rescue the phenotype of yeast deficient in Vms1, the yeast homologue of ANKZF1.
94 genes into a pool of 4653 homozygous diploid yeast deletion mutants with unique barcode sequences, fo
95 somes are positioned according to endogenous yeast DNA sequence and chromatin-remodeling network, as
97 Furthermore, when comparing the DFE across yeast, Drosophila, mice, and humans, the average selecti
100 s, and seven UM-associated substitutions, in yeast eIF1A suppresses initiation at near-cognate UUG co
104 aegypti and its successful transposition in yeast facilitated the characterization of key steps in M
105 study, we describe data indicating that the yeast family members Ltc1 and Ltc3/4 function at the vac
106 , this regulation is particularly crucial in yeast for the stress-induced transient elevation of PI3,
107 ion effect is made possible by the choice of yeast frataxin, a protein that undergoes cold denaturati
108 Surprisingly, genetic screening reveals that yeast FTase can modify sequences longer than the canonic
109 ammalian MLH1-PMS2 heterodimer; MLH1-PMS1 in yeast) functions in early steps of mismatch repair as a
110 highly conserved Rho-GTPase Cdc42p promotes yeast fusion through interaction with Fus2p, a pheromone
112 Thus, SATAY allows to easily explore the yeast genome at unprecedented resolution and throughput.
114 imulations of Mig1 configuration within a 3D yeast genome model combined with a promoter-specific, fl
118 ization studies of PSGs with proteins of the yeast GFP collection, mass spectrometry, and direct stoc
125 other in vitro, and at least in the fission yeast, heterologous Oxs1 and Pap1-homologues can substit
129 ing three example separations: live and dead yeast; human cancer cells/red blood cells; and rodent fi
130 e the accuracy and workflow of bacterial and yeast ID and bacterial AST using the Accelerate Pheno sy
132 shown to activate the S-phase checkpoint in yeast in response to replicative stress, but whether thi
135 f transcriptome sequencing data from budding yeast, in high temporal resolution over ca. 2.5 cycles o
136 e most mutations showed similar behaviors in yeast, in vitro, and in Drosophila, a few showed anomalo
138 ontroversial, however, whether mammalian and yeast IRE1 use a common mechanism for ER stress sensing.
140 source of transcription-associated damage in yeast is Topoisomerase I (Top1), an enzyme that removes
141 low-pH environment of toxin-secreting killer yeasts, K28 is structurally stable and biologically acti
142 he forces that ensembles of purified budding yeast kinesin-5 Cin8 produce in microtubule gliding assa
144 kinetochore proteins Nkp1 and Nkp2, from the yeast Kluyveromyces lactis, with nanoflow electrospray i
149 hogen, typically found as a benign commensal yeast living on skin and mucosa, but poised to invade in
158 on microscopy, Bim1 causes the compaction of yeast microtubules and induces their rapid disassembly.
160 We analyzed outer membrane fractions of yeast mitochondria and identified four new channel activ
161 genomes and provides concrete evidence that yeast mitochondria lack mechanisms for removal of ribonu
162 average error rates of T7 RNAP (2 x 10(-6)), yeast mitochondrial Rpo41 (6 x 10(-6)), and human mitoch
163 o counteracts Mdm30-mediated turnover of the yeast mitofusin Fzo1 and that Mdm30 targets Ubp2 for deg
164 o be widespread and dynamically regulated on yeast mRNA, but less is known about Psi presence, regula
165 rescues the Mn-hypersensitivity of the pmr1 yeast mutant but only slightly alleviates the Zn sensiti
167 ta subunit and the RNR catalytic activity in yeast mutants depleted of individual components of the m
168 f these LDs, we screened approximately 6,000 yeast mutants for loss of targeting of the subpopulation
169 itiation at near-cognate UUG start codons in yeast mutants in which UUG selection is abnormally high.
172 covered that the myosin I protein in fission yeast, Myo1, which is required for organization of stero
174 ines spatial organization within the budding yeast nucleus, demonstrates the conserved role of genome
175 loyed a gene-centered approach utilizing the yeast one-hybrid assay to generate a network of protein-
178 us organisms ranging from bacteria to algae, yeasts, plants, crustaceans and fish such as salmon.
181 ds that the first-step mutations selected in yeast populations evolving in parallel in the presence o
183 rate that akin to mammalian cells, wild-type yeast possess only two TRAPP complexes, TRAPPII and TRAP
184 ng as a crucial step in the formation of the yeast prion [PSI (+)], formed by the translation termina
185 described ability of Cur1 to antagonize the yeast prion [URE3], it enhances propagation and phenotyp
187 rones and other cellular components cure the yeast prions [PSI(+)] (formed by Sup35p) or [URE3] (base
193 tial, we previously interrogated the budding yeast proteome to identify candidates that function in t
194 st of genes important for meiosis in fission yeast, providing a valuable resource to advance our mole
202 Here we report high-resolution structures of yeast Rev1 with three BP-N (2)-dG adducts, namely the 10
203 Heterologous expression of TmELO genes in yeast revealed that TmELO1 and TmELO2 function to synthe
205 se-grained mathematical model of the fission yeast ring to explore essential consequences of the rece
207 amine the function of Swi1 and Swi3, fission yeast's primary FPC components, to elucidate how replica
208 uction of salidroside can be achieved in the yeast Saccharomyces cerevisiae as well as the plant Nico
209 ss-response element in gene promoters in the yeast Saccharomyces cerevisiae However, the roles of Msn
212 evels of endogenous hydrogen peroxide in the yeast Saccharomyces cerevisiae promote site-specific end
213 structures at up to 2.6 A resolution of the yeast Saccharomyces cerevisiae separase-securin complex.
214 4 subunit of the ubiquitin ligase GID in the yeast Saccharomyces cerevisiae targeted the gluconeogeni
215 ear microtubule (MT) dynamics in the budding yeast Saccharomyces cerevisiae This activity requires in
221 antitative attributes of PKA dynamics in the yeast Saccharomyces cerevisiae, we developed an optogene
225 o PKC orthologs Pck1 and Pck2 in the fission yeast Schizosaccharomyces pombe operate in a redundant f
226 ent-binding proteins (SREBPs) in the fission yeast Schizosaccharomyces pombe regulate lipid homeostas
232 ic complementation of glycolate transport in yeast showed that BASS6 was capable of glycolate transpo
233 commonly misidentified as several different yeast species by commercially available phenotypic ident
234 r enormous evolutionary diversity (there are yeast species in every subphylum of Dikarya) sparked cur
235 vage and polyadenylation sites (PASs) in two yeast species, S. cerevisiae and S. pombe Although >80%
238 ing centers (MTOCs; mammalian centrosome and yeast spindle pole body [SPB]) nucleate more astral micr
240 cued the K(+) -uptake-defective phenotype of yeast strain CY162, suppressed the salt-sensitive phenot
242 , suppressed the salt-sensitive phenotype of yeast strain G19, and complemented the low-K(+) -sensiti
245 ative de novo mutations failed to complement yeast strains lacking the EEF1A ortholog showing a major
250 ion of MS is a unique feature of respiratory yeasts such as P. pastoris and C. albicans, and it may h
251 variant and levoglucosan kinase (LGK) using yeast surface display (YSD) screening and a twin-arginin
252 cular, this protein will enable mirror-image yeast surface display experiments to identify all-d pept
253 ented with an experimental platform based on yeast surface display for affinity and specificity scree
254 , we integrated a computational method and a yeast surface display technique to obtain highly specifi
256 fore, knowledge from the budding and fission yeast systems illuminates highly conserved molecular mec
258 Rhodotorula (Rhodosporidium) toruloides is a yeast that naturally synthesizes substantial amounts of
259 hat acts to kill gametes (known as spores in yeast) that do not inherit the gene from heterozygotes.
262 nd shift assays, fluorescence Job plots, and yeast three-hybrid assays, we investigate the interactio
263 he endogenous cellular regulatory network of yeast to enhance compatibility with synthetic protein an
264 f homologous chromosomes during meiosis from yeast to humans, plays important roles in promoting inte
268 in kinase (MAPK) pathways are conserved from yeast to man and regulate a variety of cellular processe
269 investigate the adaptive response of budding yeast to temporally controlled H2O2 stress patterns.
270 ex from cleavage, and this has been shown in yeasts to be mediated by recruitment of the protein phos
272 report the crystal structure of the fission yeast Tpz1(475-508)-Poz1-Rap1(467-496) complex that prov
273 asure the global RNA-binding dynamics of the yeast transcription termination factor Nab3 in response
275 Here, we show how the s(2) modification in yeast tRNA(Lys) affects mRNA decoding and tRNA-mRNA tran
277 istone deacetylase subunits were observed in yeast two-hybrid and bimolecular fluorescence assays, co
278 RNA-seq and proteomics data together with yeast two-hybrid assays suggest that MS23 along with MS3
281 Here, we report the cryoEM structure of yeast U1 snRNP at 3.6 A resolution with atomic models fo
282 econstitute post-transcriptional assembly of yeast U6 snRNP in vitro, and propose a model for U6 snRN
283 d time-resolved metabolomics measurements in yeast under salt and pheromone stimulation and developed
287 ently determined a cryo-EM reconstruction of yeast Vo The structure indicated that, when V1 is releas
289 stigation, Saccharomyces cerevisiae (baker's yeast) was engineered to produce short hairpin RNAs (shR
290 dies are motivated by the mating response of yeast, we believe our results and simulation methods wil
292 pring representation of chromatin in budding yeast, we find enrichment of protein-mediated, dynamic c
294 his assay to over 1,500 promoter variants in yeast, we reveal pronounced differences in the dependenc
295 main eisosome BAR-domain protein in fission yeast, we visualized whole eisosomes and, after photoble
297 We have found that Def1 copurifies from yeast whole-cell extract with TFIIH, the largest general
300 nteraction studies further demonstrated that yeast yUtp23 and human hUTP23 directly interact with the
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