ライフサイエンスコーパス: ylidene

1 2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene).

2 t ([(i)Pr2Im] = 1,3-di(isopropyl)imidazole-2-ylidene).

3 es ligands (IMes = N,N'-dimesityl-imidazol-2-ylidene).

4 s = 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene).

5 (2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene).

6 Pt(NHC)3Cl]Cl (NHC = 1,3-dimethyl imidazol-2-ylidene).

7 C = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene).

8 2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene).

9 IPr=1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene).

10 lene, maleic anhydride, pyridine, imidazol-2-ylidene).

11 pylphenyl-4,6-diketo-5,5-dimethylpyrimidin-2-ylidene.

12 ene is compared with that of spiro[2.3]hex-4-ylidene.

13 own to be different from that of imidazole-2-ylidenes.

14 acoordinate with a Ph group and two oxazol-2-ylidenes.

15 Pr [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene].

16 Bicyclo[3.2.1]oct-6-en-8-ylidene (1) can assume either the conformation of "class

17 The basicity of 1,3-di-tert-butylimidazol-2-ylidene (1) was measured in THF against three hydrocarbo

18 lose to those of 1,3-dimethylimidazolidine-2-ylidene (1).

19 uIm)3(-) = phenyltris(3-tert-butylimidazol-2-ylidene)), (1) low-spin d(3) (S = 1/2) coordination comp

20 lysis at -80 degrees C of 2,4,6-tri(propan-2-ylidene)-1,3,5-trioxane.

21 -11H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-ylidene)-1-piperidinyl]-2-oxoethyl]pyridine N-oxide wher

22 3-6-methyl)-3-(2,6-dimethylphenyl)imidazol-2-ylidene-1-yl (the deprotonated form of IXy); Cp* = eta(5

23 lcarbenes 8 and 11, thiacyclohexa-3,5-dien-2-ylidene, 10, and thiacyclohexa-2,3,5-triene, 6.

24 nd spectra are obtained from the imidazole-2-ylidene (13)C atoms that are not bound to Fe.

25 (1,3-bis(2,4,6-trimethylphenyl)imidazolin-2-ylidene) 13, SIPr (1,3-bis(2,6-diisopropylphenyl)imidazo

26 (1,3-bis(2,6-diisopropylphenyl)imidazolin-2-ylidene) 14, IPr (1,3-bis(2,6-diisopropylphenyl)imidazol

27 Pr (1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) 15, IMes (1,3-bis(2,4,6-trimethylphenyl)imidazo

28 es (1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene) 16).

29 rmolysis of N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-1H-pyrazol-5-amines 3 gives 1H-pyrazolo[3,4-d]t

30 in products N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-1H-pyrazol-5-amines 3, and 6H-pyrazolo[3,4-c]is

31 eacting (Z)-N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-1H-pyrazol-5-amines 5 with Et2NH and then with

32 yrazol-1-yl)-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene ]-2,3-dihydro-1H-indol-2-ones 1-23 and 3-(3,5-di

33 adduct formed between [Au(9-methylcaffein-8-ylidene)2 ](+) and Tel 23 DNA G-quadruplex was solved.

34 arbene gold(I) complex [Au(9-methylcaffein-8-ylidene)2 ]BF4 is an exceptional organometallic compound

35 3-(2-methoxyethyl)-4,5-dimethylthiazol-2(3H)-ylidene)-2,2,3,3-tetra methyl-cyclopropanecarboxamide ([

36 (3-(4-fluorobutyl)-4,5-dimethylthiazol-2(3H)-ylidene)-2,2,3,3-tetramethyl-c yclopropanecarboxamide (2

37 n both ligand [isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2-yl)carbamoyl]acet ate (

38 ] 2 (L2 =(p-tolyl)2 B[1-(1-adamantyl)-3-yl-2-ylidene]2 ) has been synthesized by salt-metathesis reac

39 generate endo-tricyclo[3.2.1.0(2,4)]octan-8-ylidene (3) by either photolysis or thermolysis.

40 oic acid (RA) analogues [8-(2'-cyclohexen-1'-ylidene)-3, 7-dimethyl-2,4,6-octatrienoic acids with dif

41 6Z,8Z)-8-(3',4'-Dihydro-1'(2H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,3,6-o ctatrienoinic acid (UAB30)

42 B30 [8-(3', 4'-dihydro-1'(2'H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,4, 6-octatrienoic acid], which h

43 Z,8E)-8-(3',4'-Dihydro-1'(2'H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,4,6- octatrienoic acid, 9cUAB30,

44 trans-retinoids that are 8-(2'-cyclohexen-1'-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acids with diff

45 hilic carbene 1,3,4,5-tetramethyl-imidazol-2-ylidene (4), the ring-opening polymerization occurs with

46 2 inhibitor 3-[1-(3H-imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-on e (SU9516) wer

47 w here that 3-[1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-on e (SU9516), a

48 3,5-diylidenethiomorpholine-2,6-dithione or ylidene-6-thioxo[1,2]dithiolo[3,4-b][1,4]thiazin-3-one g

49 yclophanes 18-20, the 9,10-bis(1,3-dithiol-2-ylidene)-9, 10-dihydroanthracene moieties adopt a saddle

50 hly pi-extended 9,10-bis(benzo-1,3-dithiol-2-ylidene)-9,10-dihydroanthracene (sExTTF) moiety, which e

51 Imidazol-2-ylidenes, a family of N-heterocyclic carbenes (NHC), are

52 4-methyl-5-oxo-3-vinyl-(1, 5-dihydropyrrol-2-ylidene)acetamide and 3-methyl-5-oxo-4-vinyl-(1, 5-dihyd

53 3-methyl-5-oxo-4-vinyl-(1, 5-dihydropyrrol-2-ylidene)acetamide and the third was 4-methyl-3-vinylmale

54 8,9-tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylidene)acetic acid showed a 39% reduction (P = 0.0056)

55 3-(2,6-diethylphenyl)-4,5-dimethylthiazol-2-ylidene afforded the most efficient and stable catalysts

56 dation of organoboron L2PhB: 1 (L = oxazol-2-ylidene) afforded a dicationic diborane(6) species [L2Ph

57 (IPr = 1,3-bis(diisopropylphenyl)imidazol-2-ylidene), alkenyldiazo carbonyl species react with organ

58 cules of six N-(1-methyl-4-oxoimidazolidin-2-ylidene) alpha-amino acids and the development of a stab

59 y up-take of N-(1-methyl-4-oxoimidazolidin-2-ylidene) alpha-amino acids in hyperglycemic diabetes pat

60 N-(1-Methyl-4-oxoimidazolidin-2-ylidene) alpha-amino acids were recently identified in r

61 h alternative NHC isomers, namely imidazol-5-ylidenes (also termed abnormal NHCs or aNHCs, because th

62 yl)furan-2-yl)methylene)-4-ox othiazolidin-2-ylidene)amino)benzoic acid (PT-1), which attenuates the

63 entration of N-(1-methyl-4-oxoimidazolidin-2-ylidene) aminopropionic acid was elevated in plasma and

64 rimethyl-1 -azatricyclo[3.3.1.1(3,7)]decan-2-ylidene, an aminocarbene without pi conjugation, has bee

65 ) complexes with 1,3-substituted imidazole-2-ylidene and benzimidazole-2-ylidene ligands of the type

66 o appreciable differences between imidazol-2-ylidene and imidazolin-2-ylidene catalysts were observed

67 energy surface of 1,6-methano[10]annulen-11-ylidene and its isomers has been investigated by density

68 dimesityl-4,6-diketo-5,5-dimethylpyrimidin-2-ylidene and N,N'-diisopropylphenyl-4,6-diketo-5,5-dimeth

69 t (H2Im = 1,3-dimethyl-4,5-dihydroimidazol-2-ylidene) and a -PPh2 group connected through structurall

70 r = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) and O2 leads to the surprising discovery that a

71 s = 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene) and the second to the methoxymethylidene metal

72 l-1,1'-bis(p-tolyl)-4,4'-bis(1,2,3-triazol-5-ylidene)), and show that the superior sigma-donor and pi

73 arbenes (NHC = 1,3,4,5-tetramethylimidazol-2-ylidene), and having chloride as a countercation were su

74 , including the poor pi-accepting imidazol-2-ylidene, and phosphines giving rise to the corresponding

75 s catalyzed by imidazol-2-ylidene, triazol-3-ylidene, and thiazol-2-ylidene have been investigated co

76 N-(4-Chloro-5H-1,2,3-dithiazol-5-ylidene)anilines react with DABCO in hot PhCl to give N-

77 roethyl)piperazin-1-yl]-5H-1,2,3-dithiazol-5-ylidene}anilines in high yields (70-92%).

78 r = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) are disclosed.

79 2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene) as a precatalyst for the anaerobic oxidation of

80 ed by coupling functionalized benzimidazol-2-ylidenes, as their free N-heterocyclic carbenes or gener

81 Protonation of the ylidene at the N(7/9)-atom yields complexes bearing a pr

82 ran-2(3H)-ones and 6-methyl-3-(pyridin-2(1H)-ylidene)benzofuran-2(3H)-one.

83 providing 6-methyl-3-(1-methylpyridin-2(1H)-ylidene)benzofuran-2(3H)-one.

84 ffording a novel class of 3-(pyrimidin-2(1H)-ylidene)benzofuran-2(3H)-ones and 6-methyl-3-(pyridin-2(

85 controlled assemblage of a pivotal (Z)-gamma-ylidene-beta-bromobutenolide intermediate by stereodirec

86 ntified FMP-Red-Dye as 5,5'-(1-propen-1-yl-3-ylidene)bis[1,3-dimethyl-2-thio-barbituric acid].

87 example, reaction of 1,3-dimethylimidazol-2-ylidene borane (diMe-Imd-BH3) with 10% I2 followed by ad

88 ith readily available 1,3-dimethylimidazol-2-ylidene borane and a water-soluble triazole relative are

89 The synthesis of 1,3-dimethylimidazol-2-ylidene borane has been conducted on scales up to 100 mm

90 1-Butyl-3-methylimidazol-2-ylidene borane has been synthesized directly from two in

91 ith readily available 1,3-dimethylimidazol-2-ylidene borane provides reductively decyanated products

92 on of bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene borane with dimethyl acetylenedicarboxylate give

93 Reactions of 1,3-dimethylimidazol-2-ylidene-borane (diMe-Imd-BH3) and related NHC-boranes wi

94 1,3-Dialkylimidazol-2-ylidene boranes have been made in moderate yields (typic

95 ive B,B-disubstituted 1,3-dimethylimidazol-2-ylidene boranes.

96 m)(3)(-) = phenyltris(3-tert-butylimidazol-2-ylidene)borato, BAr(F24) = B(3,5-(CF(3))(2)C(6)H(3))(4)(

97 for the reverse protonation of the triazol-3-ylidenes by solvent water is close to that for dielectri

98 he Breslow intermediate in case of thiazol-2-ylidene (by ca. 10 kcal/mol) compared to the other two c

99 r = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene; Bzl-3,5Me = 1,3-bis(3,5-dimethylphenyl)-1H-benz

100 thylamino-4-methyl-2-phenyl)cyclobut-2-ene-1-ylidene]c hromium (1e) leads to antiaromatic conjugate a

101 the carbon-carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized.

102 es =1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene] can be readily isolated and manipulated in solu

103 was simplified by generating the imidazol-2-ylidene catalysts in situ.

104 between imidazol-2-ylidene and imidazolin-2-ylidene catalysts were observed.

105 3-diethylamino-2,4-dimethyl)cyclobut-2-ene-1-ylidene]chromi um (1d) and pentacarbonyl[(3-diethylamino

106 -diethylamino-2,5-dimethyl)cyclopent-2-ene-1-ylidene]chromi um (5), [dimethylamino(methyl)carbene]pen

107 =1,3-bis(2,4,6-trimethylphenyl), imidazole-2-ylidene; COD=cyclooctadiene] catalyst onto silica partic

108 pendent on the sterics of the benzimidazol-2-ylidene component and the electronics of the azide compo

109 1; IXy=1,3-bis(2,6-dimethylphenyl)imidazol-2-ylidene; Cp*=eta(5) -C5 Me5 ; Trip=2,4,6-iPr3 C6 H2 ) wi

110 utylphenyl)methyl]-4-methylphenyl]imidazol-2-ylidene) CuOPh [(IPr**)CuOPh] reacts with poly(methylhyd

111 ; IPr = 1,3-bis(diisopropyl)phenylimidazol-2-ylidene; dbabh = 2,3:5,6-dibenzo-7-azabicyclo[2.2.1]hept

112 NO)(2)) (NHC-iPr = 1,3-diisopropylimidazol-2-ylidene) demonstrate distinct differences of the isomer

113 3,4-triphenyl-4,5-dihydro-1H-1,2,4-triazol-5-ylidene) derivatives as methanol insertion products, (Rx

114 nt resonance contributor of penta-1,4-diyn-3-ylidene (diethynylcarbene, H-C[triple bond]C-:C-C[triple

115 reas cis-dichlorido[(1,3-dibenzyl)imidazol-2-ylidene](dimethyl sulfoxide) platinum(II) 3a induced G2/

116 of 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (dipp-Imd-BH(2)X, X = halide or sulfonate) have

117 r = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene; DIPP = 2,6-(i)Pr2-C6H3) is reported.

118 A series of new 4H-pyran-4-ylidene donor-based chromophores with a thiophene ring i

119 rimethyl-3a,4-dihydro-2,1-benzisoxazol-5(3H)-ylidene)ethanal (10), the trans isomers recombined formi

120 y-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid (NCS-382) is an antagonist for ga

121 use of 1-(4,4-dimethyl-2, 6-dioxocyclohex-1-ylidene) ethyl (Dde) in place of Z protection on the ami

122 (1) (where TIMEN = (tris[2-(3-arylimidazol-2-ylidene)ethyl]amine) reacts with CO, one-electron oxidiz

123 where TIMEN(xyl) = tris[2-(3-xylylimidazol-2-ylidene)ethyl]amine) yields the isolable molecular Mn(IV

124 presence of electron donor 9-(1,3-dithiol-2-ylidene)fluorene (compounds 13 and 14) and electron acce

125 , bithiophene, 9-(4,5-dimethyl-1,3-dithiol-2-ylidene)fluorene, and triphenylamine], have been synthes

126 he TTF-OXD and 9-(4,5-dimethyl-1,3-dithiol-2-ylidene)fluorene-OXD hybrids, 10d, 10g, 11, and 13, are

127 ,3-diethyl-4,5-bis(4-fluorophenyl)imidazol-2-ylidene]gold(I) bromide 3b as the most cytotoxic compoun

128 ationic bis[1,3-diethyl-4,5-diarylimidazol-2-ylidene]gold(I) complexes with 4-OCH(3) or 4-F substitue

129 SiMe3 )2 (ITMe=1,3,4,5-tetramethylimidazol-2-ylidene) has been synthesized by mild oxidative cleavage

130 imethylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidene] has been structurally characterized and display

131 = N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene], has been developed.

132 -2-ylidene, triazol-3-ylidene, and thiazol-2-ylidene have been investigated computationally.

133 2)IMes = 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene) have been prepared; these complexes are readily

134 lic carbenes (3-methyl-indol-2-yl)imidazol-2-ylidenes, however, can be trapped by sulfur, triethylbor

135 thyl-5-oxo-3-(phosphonatooxymethyl)pyridin-2-ylidene]hydr azinyl]benzoate as a 14-3-3 inhibitor, whic

136 e development of (5-oxo-1,5-dihydropyrazol-4-ylidene)hydrazines which exhibited efficacies equivalent

137 cleophilicity, 1,3-di-tert-butylimidazolin-2-ylidene (I(t)Bu), 1,3-dimesitylimidazolin-2-ylidene (IMe

138 ), 1,3-bis-(2,4,6-trimethylphenyl)imidazol-2-ylidene (IMes) and 1,3-bis-(2,6-diisopropylphenyl)imidaz

139 ene 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene (IMes) and spanning formal oxidation states W(0)

140 NHC=1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene (IMes) or 1,3-bis(2,6-diisopropylphenyl)imidazol

141 -ylidene (I(t)Bu), 1,3-dimesitylimidazolin-2-ylidene (IMes), and 1,3,4-triphenyl-4,5-dihydro-1H-1,2,4

142 ith 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene (IMes, 1) generates the poly(carbosiloxane) p(TM

143 (N,N'-bis(2,6-diisopropylphenyl)imidazol)-2-ylidene], in the Suzuki-Miyaura cross-coupling reaction

144 s = 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene), indicating that the bonds are the same within

145 4-(benzo[d][1,3]dioxol-5-yl)-2-oxobut-3-en-1-ylidene)indolin-2-one (designated herein as HOI-07) was

146 2-(4'-OBzl-1',7'-dihydro-7'-oxo-6'H-indol-6'-ylidene)indolin-3-one, in which a pyrrole ring and a ben

147 (3Z)-6-bromo-3-[(3E)-3-hydroxyiminoindolin-2-ylidene]indolin-2-one (15) as a potent, direct, and reve

148 red 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr) or its saturated analogue, 1,3-bis(2,6-dii

149 or 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr)), towards [Na(dioxane)x ][PnCO] (Pn=P, As)

150 nd 1,3-bis-(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr), and of the two corresponding ruthenium-ba

151 idation of an iridium-N-dimethylimidazolin-2-ylidene (Ir-NHC-Me2) complex adsorbed on a polycrystalli

152 endo-Tricyclo[3.2.1.0(2,4)]oct-8-ylidene is a foiled carbene reaction intermediate.

153 Spiro[3.3]hept-1-ylidene is a markedly strained carbene reaction intermed

154 alcohol adducts of 1,3-dimesitylimidazolin-2-ylidene is described.

155 e NHC 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene is employed as the external base.

156 , and the N-heterocyclic carbene quinoline-2-ylidene is not formed as a tautomer.

157 e2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene) is obtained from the reaction of the alpha-chlo

158 1,3-bis(2,6-diisopropylphenyl)imidazolidin-2-ylidene) is used in place of Ni(COD)2/SIPr.HBF4/KO(t)Bu

159 re HL(Ph) is 1,3,4-triphenyl-1,2,4-triazol-5-ylidene, is available from (NBu(4))[TcNCl(4)] and HL(Ph)

160 [IXy = 1,3-bis(2,6-dimethylphenyl)imidazol-2-ylidene; IXy-H = 1-(2-CH2C6H3-6-methyl)-3-(2,6-dimethylp

161 IXy = 1,3-bis(2,6-dimethylphenyl)imidazol-2-ylidene; "IXy-H" is the deprotonated form of IXy) exhibi

162 hylcycloheptatrienyl)-4,5-dihydroimidazol-2- ylidene}L(2)(PCy(3))Cl(2).

163 eneglycolato) with 1,3-dimethylimidazoline-2-ylidene (L1), 1,1'-methylene-3,3'-dimethyl-4,4'-diimidaz

164 complexes bearing a (1,3-dibenzyl)imidazol-2-ylidene ligand but different leaving groups trans to it

165 t platform in which the anchoring imidazol-2-ylidene ligand IPr((NMe2)2) incorporates two dimethylami

166 ulting Pt(II) complexes feature a C(8)-bound ylidene ligand.

167 ate, the aryl substituents of the thiazole-2-ylidene ligands are located above the empty coordination

168 Among five thiazole-2-ylidene ligands examined, 3-(2,4,6-trimethylphenyl)- and

169 sis catalysts bearing a series of thiazole-2-ylidene ligands has been prepared.

170 uted imidazole-2-ylidene and benzimidazole-2-ylidene ligands of the type NHC-Au-L (NHC = N-heterocycl

171 itions of the N-aryl group of the thiazole-2-ylidene ligands, the phosphine-free catalysts lose stabi

172 )2-(5,6-dihydro-4H-cyclopenta [b]thiophene-4-ylidene)malonitrile)-2-(2,3-dihydrothieno[3,4-b][1,4]dio

173 e transfer from diphenylamine was: 2-pyran-4-ylidene malononitrile (pyranone) > dicyanovinyl > bis(di

174 An analogue with the 2-pyran-4-ylidene malononitrile acceptor group exhibited a nearly

175 bipolar 2,7- and 3,6-disubstituted fluoren-9-ylidene malononitrile derivatives (4 and 9) is described

176 2-(5,6-difluoro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile to yield a fused-ring electron acc

177 2-[1-aryl-5-imino-2-phenyl-1H-imidazol-4(5H)-ylidene]malononitriles 13 in 84-92% yields, while in MeO

178 -2-[2-phenyl-4-(arylimino)-1H-imidazol-5(4H)-ylidene]malononitriles 14 are formed in 85-94% yields.

179 76 (N-(2,3-diphenyl-1,2, 4-thiadiazol-5-(2H)-ylidene)methanamine), has been identified as an inhibito

180 on of several (4-chloro-5H-1,2,3-dithiazol-5-ylidene)methanes with DABCO failed to give {4-[N-(2-chlo

181 roethyl)piperazin-1-yl]-5H-1,2,3-dithiazol-5-ylidene}methanes, these can be prepared in moderate yiel

182 (2-ethoxy-2-oxoethyl)-2,4-dioxothiazolidin-5-ylidene)methyl )furan-2-yl)benzoic acid (1a) that exhibi

183 o-6,7-dihydro-8H-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}-N-(2- pyridyl)benzenesulfonamide (

184 yl-cyclohexylmethyl)-2,4-dioxo-thiazolidin-5-ylidene-methyl]-phen yl}-4-nitro-3-trifluoro-methyl-benz

185 cyclic carbene (NHC) bis-(N-Dipp-imidazole-2-ylidene)methylene (abbreviated {((Dipp)C:)2CH2}) (Dipp =

186 yclic carbene) ligand bis(N-Dipp-imidazole-2-ylidene)methylene (bisNHC, 1) affords [(bisNHC)AlBr2](+)

187 pounds 9a and 9b and also two 1,3-dithiole-2-ylidene moieties are connected by a pi bridge to the ele

188 -free stable carbenes, especially imidazol-2-ylidenes [N-heterocyclic carbenes (NHCs)], has led to nu

189 ing a 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-alkylacetamide skeleton is reported.

190 N-(3-methylamino-5,5-dimethyl-2-cyclohexen-1-ylidene)-N-methylaminium iodide (3a).

191 for the construction of a C-C bond between 3-ylidene oxindoles and electron-rich arenes has been succ

192 ective Michael addition of nitroalkanes to 3-ylidene oxindoles is described, mediated by thiourea-bas

193 A cascade reaction of 3-ylidene oxindoles with phenols and beta-naphthol resulte

194 opyrazoles 1 and 3-(3-oxo-2-benzofuran-1(3H)-ylidene)pentane-2,4-dione (2).

195 s)CCC ((Mes)CCC = bis(mesityl-benzimidazol-2-ylidene)phenyl), is described.

196 P)CCC = bis(diisopropylphenyl-benzimidazol-2-ylidene)phenyl); X = Cl or Br) with halogen and halogen

197 tyl peroxide with N,N'-di-t-butyl-imidazol-2-ylidene phenylborane.

198 o-11H-benzo [5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine, Sch 44342, 1, with their chemical st

199 rbene 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene (Pr(i)2NHCMe2) has been found to stabilize the f

200 le intermediate, N-(3-phenyl-1H-isochromen-1-ylidene)propan-1-amine.

201 conjugated unit 2-(3-amino-5-oxopyrrolidin-2-ylidene)propanoic acid.

202 the corresponding 4-N-(N-methylpyrrolidin-2-ylidene)-protected H-phosphonate monomer 7.

203 diisopropylphenyl]-1,3-dihydro-2H-imidazol-2-ylidene) provided only the alkene hydroarylation product

204 IPr = 1,3-bis(diisopropyl)phenylimidazolin-2-ylidene; Py = pyridine; IPr = 1,3-bis(diisopropyl)phenyl

205 is(3,5-dimethylphenyl)-1H-benzo[d]imidazol-2-ylidene; py2-BMe2 = di(2-pyridyl)dimethylborate).

206 The bis(arylimidazol-2-ylidene)pyridine cobalt methyl complex, ((iPr)CNC)CoCH3,

207 d definitive evidence for bis(arylimidazol-2-ylidene)pyridine radicals in reduced cobalt chemistry.

208 2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene; R = H, Me, gem-Me2, Ph] have been synthesized a

209 2)IMes = 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene; R = Ph, Me, H, CH=CMe(2)) triggers carbene inse

210 xes [R-iso-BIPY = N-(2-pyridyl)-R-pyridine-2-ylidene; (R = 4-H, 1; 4-tert-butyl, 2; 4-dimethylamino,

211 and IMe.H2BN3 (IMe = 2,6-dimethylimidazole-2-ylidene) reveals significant differences in the reactivi

212 vity of 1,3-dimesityl-4,5-dihydroimidazole-2-ylidene ruthenium carbene catalyst 3 significantly incre

213 Mebim-py = 3-methyl-1-pyridylbenzimidazol-2-ylidene; S = solvent) is a robust, reactive electrocatal

214 table pyrimidin-1,3-diium and pyrimidinium-2-ylidene salts.

215 The NHC complex (1-ethyl-3-methylimidazol-2-ylidene)silver(I) chloride is an ionic liquid, and was f

216 6-diisopropylphenyl)-4,5-dihydroimidazolin-2-ylidene (SIPr).

217 = N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene, SIPr = N,N'-bis(2,6-diisopropylphenyl)-4,5-dihy

218 talloporphyrins fused with the 1,3-dithiol-2-ylidene subunits present in tetrathiafulvalene, termed M

219 r = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) system presents the highest activity with respe

220 HC) 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene, the so-called IDipp, catalyzes hydrogen/deuteri

221 C 1,3-bis(2,4,6-trimethylphenyl)imidazolin-2-ylidene, the so-called SIMes, is inefficient for the sam

222 r = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) through activation of Pd(IPr)(eta(3)-allyl)Cl t

223 3,4-triphenyl-4,5-dihydro-1H-1,2,4-triazol-5-ylidene (TPT), and two representative acrylic monomers,

224 from three aldehydes catalyzed by imidazol-2-ylidene, triazol-3-ylidene, and thiazol-2-ylidene have b

225 of IMes-N2O (IMes = 1,3-dimesitylimidazol-2-ylidene) was explored in reactions with the complexes Cu

226 (IPr = 1,3-bis(diisopropylphenyl)imidazol-2-ylidene) was found to be a highly effective catalyst for

227 ) and the NHC (1,3-bis(cyclohexyl)imidazol-2-ylidene), which was proposed to act as a source of nucle

228 d(H)(OBz), 1 (IMes = 1,3-dimesitylimidazol-2-ylidene), which yields trans-(IMes) 2Pd(OOH)(OBz), 2.

229 physiologic conditions to yield a thiazol-2-ylidene, which is an N-heterocyclic carbene that has hig

230 = 1,3-bis(2,6-diisopropylphenyl)imidazolin-2-ylidene) with ClMg{CH(SiMe3)2}.Et2O affords (IPr)Ni{CH(S

231 H2IMes = 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene) with ethylene was found to generate unidentifie

232 (2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene) with oxygen affords the pink eta(2)-O(2) hydrid