ライフサイエンスコーパス: zebrafish mutant

1 GFR2 signaling or using a vascular deficient zebrafish mutant.

2 epileptic activities observed in a mind bomb zebrafish mutant.

3 nt mutant ARL13B rescued the Arl13b scorpion zebrafish mutant.

4 opment necessary for the characterization of zebrafish mutants.

5 examine cmlc2 and vmhc expression in several zebrafish mutants.

6 ge of defects similar to those of dorsalized zebrafish mutants.

7 drocyte number and myelinated axons in gpr56 zebrafish mutants.

8 Here, we discuss work on zebrafish mutants affecting gastrulation and patterning

9 Here we analyse a set of zebrafish mutants and arrive at a different interpretati

10 Using zebrafish mutants and in vivo imaging, we identified the

11 the exocyst complex, by analyzing both exoc5 zebrafish mutants, and photoreceptor-specific Exoc5 knoc

12 zygous kcnh2 mutations and expand the use of zebrafish mutants as a model system to study human arrhy

13 on in somite measurements across a number of zebrafish mutants; (b) the delayed formation of somites

14 ral patterns of gene expression in different zebrafish mutant backgrounds allow further quantitative

15 netic analyses of a recessive, larval lethal zebrafish mutant, bal(a69), characterized by severe eye

16 cterized the ocular defects in the recessive zebrafish mutant blowout that presents with a variably p

17 , the study was focused on a reduced melanin zebrafish mutant, brass.

18 roadly rescue morphology and motility in the zebrafish mutant, but alter motor axon morphology, demon

19 those of phenotypic rescue of headless/tcf3 zebrafish mutants by mouse Six3, demonstrate that region

20 Here, we describe a unique zebrafish mutant, caliban (clbn), with arrested developm

21 A homozygous lethal zebrafish mutant, cassiopeia (csp), was identified by a

22 sible for the cell cycle defects seen in the zebrafish mutant, cease&desist (cds).

23 We previously identified a zebrafish mutant ceylon (cey) that has a severe reductio

24 ellular, and electrophysiological basis of a zebrafish mutant characterized by ventricular asystole.

25 We performed a deep characterization of the zebrafish mutant Chihuahua, that carries a G574D (p.G736

26 In the zebrafish mutant cloche (clo), SCL expression is nearly

27 t hematopoietic and vascular deficits in the zebrafish mutant cloche.

28 The zebrafish mutant colgate (col)/histone deacetylase1 (hda

29 We utilized zebrafish mutant combinations that disrupt Chordin and m

30 Here we describe a zebrafish mutant crimsonless (crs) with a developmental

31 In the zebrafish mutant cyclops (Cyc(b16)), most embryos have t

32 alling pathway, such as those mutated in the zebrafish mutants cyclops, squint and one-eyed pinhead (

33 We characterize a zebrafish mutant defective in definitive haematopoiesis

34 From a genetic screen, we identified a zebrafish mutant defective in the leo1 gene.

35 ovel genes for congenital muscle diseases, a zebrafish mutant, designated patchytail, was identified

36 The corneas of zebrafish mutants display severe abnormalities of the ep

37 2) knockdown in these cells or its loss in a zebrafish mutant disrupted cell extrusion.

38 Moreover, when expressed in mfsd2aa-morphant zebrafish, mutants failed to rescue microcephaly, BBB br

39 ectron microscopy to evaluate the corneas of zebrafish mutant for a crumbs locus oko meduzy (ome) and

40 enetic screen yielded malbec (mlb(bw306)), a zebrafish mutant for cdh5, with normal embryonic and def

41 Zebrafish mutant for foxp3a displayed excess T lymphocyt

42 Using zebrafish mutants for cav1, cav3, and cavin1b, we show t

43 To address this question, we utilized zebrafish mutants for ewsa and tp53.

44 sidedness to organ chirality, we examined 12 zebrafish mutants for initial heart tube position and la

45 We generated zebrafish mutants for pkd1 and noted cystic kidney and m

46 Here, we report the identification of zebrafish mutants for the gene encoding Structure specif

47 Here we describe a zebrafish mutant, frascati (frs), that shows profound hy

48 polarity in vertebrates, we have studied the zebrafish mutant fused somites (fss), because its paraxi

49 Analyses of zebrafish mutants have confirmed the action of chordin (

50 Many zebrafish mutants have specific defects in axon guidance

51 ies using in vitro chick models and systemic zebrafish mutants have suggested that FGF signaling is r

52 Zebrafish mutants have traditionally been obtained by us

53 Here, we report the identification of a zebrafish mutant, heart and mind, which exhibits multipl

54 , we find that the lama5 mutant is the first zebrafish mutant identified in which the pectoral fins f

55 We identified an adult-viable zebrafish mutant in which the negative feedback on the s

56 zer coordinates morphogenetic movements, and zebrafish mutants in T-box mesoderm-specific genes help

57 We show that zebrafish mutants in uhrf1 and dnmt1 have defects in len

58 ucted to characterize ocular defects in five zebrafish mutants in which core components of the v-ATPa

59 Using zebrafish mutants in which OPCs migrate out of the spina

60 mechanosensory neurons of touch-insensitive zebrafish mutants indicates that in three mutant lines t

61 that the hypochromic anaemia in shiraz (sir) zebrafish mutants is caused by deficiency of glutaredoxi

62 (vlt(m651)) is one of only five "bloodless" zebrafish mutants isolated through large-scale chemical

63 is capable of rescuing hypomyelination in a zebrafish mutant lacking BACE1.

64 In this study, we generated zebrafish mutants lacking all four zebrafish Mesp genes

65 Here, we show that in zebrafish mutants lacking ErbB3 function, neural crest c

66 Analysis of zebrafish mutants lacking functional Pten revealed that

67 Here, we report that in zebrafish mutants lacking Schwann cells in peripheral ne

68 We have cloned a zebrafish mutant, lauscher (lau), identified by its swol

69 Here, we present analysis of a zebrafish mutant line carrying a truncation mutation, W8

70 activated HIF transcriptional responses in a zebrafish mutant line harboring a point mutation in the

71 We have identified a zebrafish mutant line in which deficient emi1 gene expre

72 d genetic screen, we previously identified a zebrafish mutant line, tgct, which develops spontaneous

73 The zebrafish mutant line, twister, models SCS in terms of a

74 aB-crystallin, we generated loss-of-function zebrafish mutant lines by utilizing the CRISPR/Cas9 syst

75 However, managing zebrafish mutant lines derived from mutagenesis screens

76 ion, we screened a collection of insertional zebrafish mutant lines for expression of the HSC marker,

77 suitable for large-scale deep-phenotyping of zebrafish mutant lines, which uses optical projection to

78 quencing and mRNA rescue that the dorsalized zebrafish mutant lost-a-fin (laf) is defective in the ge

79 Furthermore, we found that the zebrafish mutants mariner (myo7aa) and sputnik (cad23) t

80 ificant risk factor for glaucoma, the bugeye zebrafish mutant may be a model organism for the disease

81 The zebrafish mutants merlot (mot) and chablis (cha) exhibit

82 decreased cilia) in a CRISPR/Cas9-engineered zebrafish mutant model provide additional support for AR

83 In zebrafish, mutant MYL4 leads to disruption of sarcomeric

84 e as a screening assay, we have identified a zebrafish mutant named fantasma (fan), which displays re

85 imary and secondary hindbrain neurons in the zebrafish mutant neckless (nls), which disrupts retinald

86 we identified a homolog of the Stil gene in zebrafish mutant (night blindness b, nbb), which showed

87 Here we describe a zebrafish mutant, no optokinetic response f(w21) (nof),

88 Studies with the zebrafish mutant nrc have revealed that loss of SynJ1 al

89 The zebrafish mutant nrc is a possible model for human retin

90 Here we present crystal, an optically clear zebrafish mutant obtained by combining different viable

91 The zebrafish mutants of CCTbeta are known to exhibit the ey

92 The zebrafish mutant, partial optokinetic response b (pob),

93 A red-blind zebrafish mutant, partial optokinetic response b (pob),

94 irst identified as the locus affected in the zebrafish mutant pescadillo, which exhibits severe defec

95 The striking similarity of zebrafish mutant phenotypes and human diseases emphasize

96 approach is based on the rescue of embryonic zebrafish mutant phenotypes by "humanized" zebrafish ort

97 In comparing mouse knockout and zebrafish mutant phenotypes, we propose a pathway for er

98 A recent analysis of the zebrafish mutant prometheus points to a previously unkno

99 A new zebrafish mutant provides further insight into how the a

100 The zebrafish mutant rapunzel has heterozygous defects in bo

101 Here, we identify a zebrafish mutant, redhead (rhd(mi149)), that exhibits em

102 The zebrafish mutant represents the first genetically 'accur

103 Here we characterize a zebrafish mutant, retsina (ret), that exhibits an erythr

104 A zebrafish mutant (s434 mutation) was identified that dis

105 The zebrafish mutant sauternes (sau) has a microcytic, hypoc

106 Our zebrafish mutant serves as a model for developing therap

107 ion of chordin in D-V patterning, dorsalized zebrafish mutants showed expanded domains of chordin exp

108 Genetic screening identifies zebrafish mutants, such as fat free, that show normal di

109 mutant phenotype of the strongest dorsalized zebrafish mutant swirl/bmp2b, revealing equivalent genet

110 ns of positional cloning, we reveal that the zebrafish mutant tennismatch is a hypomorphic allele of

111 Here, we present a zebrafish mutant that ceases mitosis at the beginning of

112 ified split top, a recessive maternal-effect zebrafish mutant that disrupts embryonic patterning upst

113 e identified brambleberry, a maternal-effect zebrafish mutant that disrupts karyomere fusion, resulti

114 Using a novel hypomorphic hnf1ba zebrafish mutant that exhibits pancreas hypoplasia, as o

115 ycat from the deletion interval of cloche, a zebrafish mutant that has dramatically reduced hematopoi

116 A recent report describes a zebrafish mutant that provides us with some enticing clu

117 ered expression patterns of lft1 and lft2 in zebrafish mutants that affect midline development sugges

118 ssues, we analyzed otic placode induction in zebrafish mutants that are deficient in prospective otic

119 Work on zebrafish mutants that develop supernumerary neuromasts

120 By analyzing zebrafish mutants that disrupt sonic hedgehog (shh) expr

121 Two zebrafish mutants that do not develop brain ventricles a

122 o rescues retinal axon pathfinding errors in zebrafish mutants that have a partial functional loss of

123 Analysis of zebrafish mutants that have defects in motor behavior ca

124 primary motoneuron specification in several zebrafish mutants that have distinct effects on paraxial

125 in one-eyed pinhead (oep) and cyclops (cyc) zebrafish mutants, the pattern is altered.

126 Here, we use a temperature-sensitive mitf zebrafish mutant to conditionally control endogenous MIT

127 To identify zebrafish mutants to serve as models for hepatic patholo

128 Here we characterized a zebrafish mutant--too few (tof)--that develops hindbrain

129 its C terminus, cause the touch-unresponsive zebrafish mutant touchdown.

130 In the zebrafish mutant unplugged, two of the three segmental m

131 Here we quantifiy four eye movements in the zebrafish mutant valentino and hox3 knockdowns, and find

132 The zebrafish mutant violet beauregarde (vbg) can be identif

133 e describe the positional cloning of a blind zebrafish mutant, wait until dark (wud), which encodes a

134 Because the zebrafish mutant was a global knockout, we also observed

135 pproach we mapped each of the five different zebrafish mutants we sequenced and identified likely cau

136 Using zebrafish mutants we show here that in the zebrafish gbx

137 ession studies and the analysis of different zebrafish mutants, we have assembled a molecular pathway

138 Using pax7a and pax7b zebrafish mutants, we identified a previously unknown re

139 sponsible for the hypochromic anaemia of the zebrafish mutant weissherbst.

140 yquem (yqe(tp61)) is a zebrafish mutant with a photosensitive porphyria syndrom

141 dx4 as the locus mutated in kugelig (kgg), a zebrafish mutant with an early defect in haematopoiesis

142 esis screen to identify no blastema (nbl), a zebrafish mutant with an early fin regeneration defect.

143 Here we isolate a zebrafish mutant with heart malformations, called 34c.

144 terized the phenotype of chardonnay (cdy), a zebrafish mutant with hypochromic, microcytic anemia, an

145 l ATPase inhibitory factor 1 (atpif1) from a zebrafish mutant with profound anaemia, pinotage (pnt (t

146 We have identified a blind zebrafish mutant with rapid degeneration of cone photore

147 e cellular bases of heart development and on zebrafish mutants with cardiac abnormalities whose study

148 left-right asymmetry defects, reminiscent of zebrafish mutants with defective cilia.

149 Today, studies of zebrafish mutants with defective heart function are prov

150 reagents, future studies of Hb switching in zebrafish mutants with defective hematopoiesis will be p

151 We identified three zebrafish mutants with defects in biliary development.

152 s screens for developmental mutants, several zebrafish mutants with defects in blood development have

153 ide a useful molecular probe for identifying zebrafish mutants with defects in granulopoiesis.

154 and will ultimately be useful in evaluating zebrafish mutants with defects in hemoglobin production

155 n important framework for future analyses of zebrafish mutants with defects in this process.

156 s epilepsy and autism, we determined whether zebrafish mutants with grossly abnormal brain structure

157 ipid mass, we performed a genetic screen for zebrafish mutants with hepatic steatosis, a pathological

158 unc45b, hsp90aa1.1 and smyd1b is specific to zebrafish mutants with myosin folding defects, and is no

159 nt and myelination, we undertook a screen of zebrafish mutants with previously characterized neural d

160 Behavioral screens have uncovered dozens of zebrafish mutants with striking visual defects.