ライフサイエンスコーパス: zinc finger

1 NEET, a protein that was also annotated as a zinc finger.

2 A binding domain with three consecutive C2H2 zinc fingers.

3 d by repeats of sequence motifs such as C2H2 zinc fingers.

4 ge in messenger RNA levels of the GLI family zinc finger 1 (GLI1) gene (HH-pathway target gene) in bi

5 N induced GPR68 expression via IKAROS family zinc finger 1 (IKZF1), resulting in increased cytosolic

6 entities (TUBEs) and the K29-selective Npl4 Zinc Finger 1 (NZF1) domain from the deubiquitinase TRAB

7 GLI family zinc finger 2 (GLI2) coordinates the Hh transcriptional

8 ence of HH/glioma-associated oncogene family zinc finger 2 (GLI2)-WNT/beta-catenin signaling crosstal

9 tation (p.R252W) in the microrchidia CW-type zinc finger 2 (MORC2) gene mapping within the linkage re

10 and A2 bases are recognized specifically by zinc finger 2 (ZF2) of CPSF-30 and the A4 and A5 bases b

11 MORC2 encodes the human CW-type zinc finger 2 protein, which is a chromatin modifier inv

12 OVOL2 encodes ovo-like zinc finger 2, a C2H2 zinc-finger transcription factor t

13 BROMO domain adjacent to zinc finger 2B (BAZ2B) is a multidomain histone-binding

14 in Vdelta2 T cells, including IKAROS family zinc finger 4 (IKZF4; Eos), integrin subunit alpha E (IT

15 odule within KDM2A consisting of a CXXC type zinc finger, a PHD domain and a newly identified Heteroc

16 ay crystal structure of the highly conserved zinc finger-acetyltransferase moiety of ESCO1 with accom

17 te that, in addition to binding DNA, PRDM9's zinc fingers also mediate its multimerization, and we sh

18 tains unique additional features including a zinc finger and an approximately 40-residue loop region

19 n thermogenic gene activation and identified zinc finger and BTB domain-containing 7b (Zbtb7b) as a p

20 We report that zinc finger and homeobox transcription factor-1 (Zeb1),

21 ive histone Lys demethylase with a conserved zinc finger and Jumonji C and N domain.

22 e bi-domain module with a RET1-specific C2H2 zinc finger and RNA recognition (RRM) domains.

23 s demonstrated that the transcription factor zinc finger and SCAN domain containing 21 (ZSCAN21) play

24 d by a conserved DNA-binding domain of three zinc fingers and a variable N-terminal domain responsibl

25 We previously identified Zhx2 (zinc fingers and homeoboxes 2) as a regulator of numerou

26 ic residues in either the distal or proximal zinc fingers, and NC-membrane binding is essential for B

27 cation in cultured cells is inhibited by the zinc finger antiviral protein (ZAP), a host factor that

28 en using small inhibitory RNAs revealed that zinc-finger antiviral protein (ZAP) inhibited virion pro

29 MBL zinc fingers are the most highly conserved portion of th

30 telomere-associated protein: TZAP (telomeric zinc finger-associated protein).

31 The transcription factor ZBED6 (zinc finger, BED-type containing 6) is a repressor of IG

32 Variation in the gene encoding zinc finger binding protein 804A (ZNF804A) is associated

33 TAGGGAA-3') and encompasses a Myc-associated zinc finger-binding site that regulates KRAS transcripti

34 The C2H2 zinc finger (C2H2-ZF) is the most numerous protein domai

35 iption factors (TFs) with multiple Cys2-His2 zinc fingers (C2H2-ZFs) remain poorly studied.

36 vitro and in vivo We show that in vitro, the zinc finger can function as an autonomous recruitment do

37 PC1, as well as the newly characterized Pab, zinc finger CCCH-type containing protein 14 (ZC3H14).

38 d polyadenosine RNA-binding protein, ZC3H14 (Zinc finger CysCysCysHis domain-containing protein 14),

39 ted ILC3s in a cell-intrinsic manner through zinc-finger-dependent inhibition of transcriptional acti

40 translational modification, catalyzed by the zinc finger DHHC domain containing (zDHHC) enzyme family

41 ylation of proteins is primarily mediated by zinc finger DHHC domain-containing palmitoyltransferases

42 CCCTC-binding factor (CTCF) is an 11 zinc finger DNA-binding domain protein that regulates ge

43 /PSD95 gene-targeting strategy: a Dlg4/PSD95 zinc finger DNA-binding domain was engineered and fused

44 The fast recruitment is mediated by the zinc finger domain and poly (ADP-ribose) (PAR).

45 and both its physical interaction to GR and zinc finger domain appear to be required for ZNF764 to r

46 quence specificity of the mutant recombinant zinc finger domain by performing biophysical measurement

47 class of over 100 previously uncharacterised zinc finger domain containing genes, located on the long

48 A/H2B, with an arginine cluster on the Sgf11 zinc finger domain docking on the conserved H2A/H2B acid

49 e solve the solution structure of the RNF126 zinc finger domain in complex with the BAG6 UBL domain.

50 a highly conserved amino acid residue in the zinc finger domain of ZNHIT3.

51 Amino acid differences in the Sp7 zinc finger domain reduce Sp7's affinity for the Sp fami

52 We have recently discovered that the ZZ zinc finger domain represents a novel small ubiquitin-li

53 and 3 (TAB2 and TAB3) by modifying the Npl4 zinc finger domain through S-adenosyl methionine-depende

54 erogeneous-backbone foldamers that mimic the zinc finger domain, a ubiquitous and biologically import

55 n, PHD2 contains an evolutionarily conserved zinc finger domain, which we have previously proposed re

56 C3) and its paralog Sertoli cell gene with a zinc finger domain-beta (SERZ-beta; DHHC7) based on over

57 identified a transcriptional repressor, GATA zinc finger domain-containing 2B (GATAD2B), that interac

58 bind GC-rich target sequences through their zinc finger domain.

59 a marked enrichment of mutations within the zinc finger domain.

60 residue within a novel viral integrase-like zinc finger domain.

61 cription, whereas deletion of its C-terminal zinc-finger domain diminished this effect.

62 patients with two mutated ankyrin repeat and zinc-finger domain-containing 1 (ANKZF1) alleles (homozy

63 ular E3 ubiquitin ligase ring-finger and CHY zinc-finger domain-containing 1 (RCHY1) as an interactin

64 ich domains, suggesting that GhCHR encodes a zinc-finger domain-containing transcription factor.

65 ing zinc finger protein 1) POZ (POxvirus and Zinc finger) domain in Schwann cells causes a neuropathy

66 d that the deletion of the POZ (POxvirus and Zinc finger) domain of the transcription factor Miz1 (My

67 amtrack, and Bric-a-brac)/POZ (POX virus and zinc finger) domain.

68 In addition to zinc finger domains in CPSF30, we identify using quantit

69 transcription factors that contain conserved zinc finger domains involved in binding to target DNA se

70 the middle of the DH that is composed of the zinc finger domains of both hexamers.

71 g over 100 human candidate RBPs that contain zinc finger domains.

72 transcriptome, and this binding requires its zinc-finger domains.

73 contains five Cys3His domains (annotated as "zinc-finger" domains).

74 To assess the effect of zinc finger E box-binding homeobox 1 transcription facto

75 Here, we identify the TF zinc finger E box-binding homeobox 2 (Zeb2) to play a cr

76 Induced by the EMT, zinc finger E-box binding homeobox 1 (ZEB1) binds and si

77 Increased expression of zinc finger E-box binding homeobox 1 (ZEB1) is associate

78 hymal transition (EMT) through activation of zinc finger E-box binding homeobox 1 (ZEB1) sensitized t

79 l-to-mesenchymal transition (EMT) regulator, Zinc finger E-box binding homeobox 1 (ZEB1), or overexpr

80 Mechanistically, we find that the ZEB1 (zinc finger E-box binding homeobox 1) transcription fact

81 volves the negative transcription regulator, zinc finger E-box binding homeobox 1.

82 transcription factors SRY-box 10 (SOX10) and zinc finger E-box binding homeobox 2 (ZEB2).

83 Elevated expression of the Zinc finger E-box binding homeobox transcription factor-

84 ZEB1 is a zinc finger E-box binding transcription factor known for

85 Here we demonstrate that zinc-finger E-box-binding homeobox 2 (Zeb2, also called

86 The Zinc-finger E-box-binding Homeobox-1 (ZEB1) is a transcr

87 We have identified ZNF503/ZEPPO2 zinc-finger elbow-related proline domain protein 2 (ZPO2

88 te immune cell interactions and a cluster of zinc finger-encoding genes associated with KMT2A rearran

89 In this study, we used a novel technology, zinc-finger engineered transcription factors, to remodel

90 ZNF281 is a zinc-finger factor involved in the control of cellular s

91 ing either the N-terminal SCAN domain or the zinc fingers failed to translocate to the nucleus and pr

92 c finger protein 12), is a member of the PHD zinc finger family of proteins.

93 C2H2 zinc-finger family members are key targets of DE miRNAs.

94 criptional regulators such as Myc-associated zinc finger from accessing their binding sites on the KR

95 In vivo, ablation of zinc finger function by a C36S/C42S Egln1 knock-in mutat

96 e, we use deletion of the monocytic leukemia zinc finger gene (Moz/Kat6a/Myst3) to examine the effect

97 In MPPs, Pcid2 interacts with the Zinc finger HIT-type containing 1 (ZNHIT1) to block Snf2

98 o tests of one of the strongest screen hits, zinc finger homeodomain 2 (Zfh2; mammalian orthologs ZFH

99 nsgenic expression of promyelocytic leukemia zinc finger; however, the promyelocytic leukemia zinc fi

100 Intriguingly, the function of this zinc finger is impaired in high-altitude-adapted Tibetan

101 ed an antibody that recognizes the conserved zinc fingers linker region (ZnFL) in multiple KRAB-ZNF.

102 iants affect a single conserved residue in a zinc finger motif crucial for DNA binding and are delete

103 JMJ27 is a nuclear protein containing a zinc-finger motif and a catalytic JmjC domain with conse

104 wn silencer for Thpok, and requires the last zinc-finger motif in Bcl11b protein, which by contrast i

105 Zinc finger motifs are distributed amongst many eukaryot

106 Further analyses show that only three zinc finger motifs are essential for PAR recognition.

107 an cells revealed that intact PIN domain and Zinc finger motifs in human hUTP23 are essential for 18S

108 ised of conserved Snail/Slug/Gfi1 (SNAG) and zinc finger motifs separated by a linker region poorly c

109 ristetraprolin (TTP) is an inducible, tandem zinc-finger mRNA binding protein that binds to adenylate

110 upregulated in cancer cells harboring ZBTB7A zinc finger mutation, leading to increased glycolysis an

111 ning of these variants, we identified ZMYM3 (zinc finger, myeloproliferative, and mental retardation-

112 ZMYND8 (zinc finger MYND (Myeloid, Nervy and DEAF-1)-type contai

113 g DSBs (5' DSBs) in yeast using an optimized zinc finger nuclease at an efficiency that approached HO

114 Zinc finger nuclease in-embryo editing of the RELA locus

115 By combining zinc finger nuclease mRNA delivery with AAV6 delivery of

116 strate that temporally optimized delivery of zinc finger nuclease mRNA via electroporation and adeno-

117 d mitochondrial DNA (mtDNA) damage and after zinc finger nuclease-mediated gene mutation correction,

118 as motor and behavioural function in a novel zinc-finger nuclease model of RTT utilizing both male an

119 developed a novel Bace1(-/-) rat line using zinc-finger nuclease technology and compared Bace1(-/-)

120 Here we develop a zinc-finger nuclease translocation reporter and screen f

121 Zinc-finger nuclease, transcription activator-like effec

122 Use of the mitochondrially targeted zinc finger-nuclease (mtZFN) results in degradation of m

123 equency and spectrum of restriction-enzyme-, zinc-finger-nuclease-, and RAG-induced DSBs.

124 The first truly targetable reagents were the zinc finger nucleases (ZFNs) showing that arbitrary DNA

125 5 (CCR5) locus in pigtailed macaque HSPCs by zinc finger nucleases (ZFNs) was feasible.

126 In addition, we used Zinc finger nucleases to generate isogenic SHANK3 knocko

127 We used zinc finger nucleases to induce stable expression of hum

128 Disruption of CCR5 using zinc finger nucleases was the first-in-human application

129 ogies for facile manipulation of the genome (zinc finger nucleases, transcription activator-like effe

130 Gene editing with zinc finger nucleases, transcription activator-like effe

131 This study optimized zinc-finger nucleases (ZFNs) and transcription activator

132 s strains (including wild-type CC-125) using zinc-finger nucleases (ZFNs), genetically encoded CRISPR

133 ctivator-like effector nucleases (TALENs) or zinc-finger nucleases (ZFNs).

134 We have used this system to identify zinc-finger nucleases that exhibit high cleavage activit

135 Here we use zinc-finger nucleases to genetically modify the multidru

136 from the non-coding region of the CCHC-type zinc finger nucleic acid-binding protein (CNBP) gene.

137 nents regulating FIT function, we identified ZINC FINGER OF ARABIDOPSIS THALIANA12 (ZAT12), an abioti

138 strate how a missense mutation in the second zinc finger of Kruppel-like factor-1 (KLF1) leads to deg

139 ng groove, which specifically recognizes the zinc fingers of JKD.

140 und that arsenite could bind directly to the zinc fingers of Tet proteins in vitro and in cells, and

141 sruption of either the catalytic activity or zinc-finger of PrimPol results in extreme G4-dependent e

142 EVI1 is a zinc finger oncoprotein involved in the development of a

143 Hence, the zinc finger ordinarily performs a critical positive regu

144 n used as a matrix for the immobilization of zinc finger peptide and fluorescent dye acrydine orange

145 transcription factor promyelocytic leukemia zinc finger (plzf) in HSC fate using the Zbtb16(lu/lu)mo

146 transcription factor promyelocytic leukemia zinc finger (PLZF) is transiently expressed during devel

147 transcription factor promyelocytic leukemia zinc finger (PLZF) seemed to control the ROS levels.

148 transcription factor promyelocytic leukemia zinc finger (PLZF), as well as expression of intracellul

149 transcription factors promyelocytic leukemia zinc finger (PLZF), eomesodermin, and T-bet and enhanced

150 al-like 4 (SALL4) and promyelocytic leukemia zinc finger (PLZF; also known as ZBTB16) are known to be

151 toylation by both Golgi-associated DHHC-type zinc finger protein (GODZ; also known as DHHC3) and its

152 the rapidly evolving Kruppel-associated box-zinc finger protein (KRAB-ZFP) family linked primarily t

153 rent classes of KAP1 target genes, including zinc finger protein (ZFP) and imprinted genes.

154 The nuclear matrix protein Cip1-interacting zinc finger protein 1 (CIZ1) promotes DNA replication in

155 Among these, the GATA-3 repressor zinc finger protein 1 (Zfpm1) emerged as a potential med

156 NT The deletion of the Miz1 (Myc-interacting zinc finger protein 1) POZ (POxvirus and Zinc finger) do

157 Zinc finger protein 106 (ZFP106) has previously been ass

158 also known as Phf12 (plant homeodomain [PHD] zinc finger protein 12), is a member of the PHD zinc fin

159 lysis identifies allele-preferred binding of Zinc finger protein 148 (ZNF148) to rs36115365-C, furthe

160 ding protein, tristetraprolin (also known as zinc finger protein 36 (ZFP36)), which is itself up-regu

161 male OB offspring had a higher expression of Zinc finger protein 423 (zfp423), a key transcription fa

162 induces DNA demethylation in the promoter of zinc finger protein 423, which renders progenitor cells

163 al. investigate the interaction of CXXC-type zinc finger protein 5 (CXXC5) with Dishevelled as one su

164 We identify zinc finger protein 568 (ZFP568), a member of the rapidl

165 We studied the Zinc Finger Protein 598 (ZNF598) using PAR-CLIP and reve

166 10C>G (p.Pro937Arg) missense mutation in the zinc finger protein 687 gene (ZNF687).

167 (5'-untranslated region variant of exon 2 of zinc finger protein 750 (ZNF750), and in an intron of TB

168 ory pathways, including STAT3, NFkappaB, and zinc finger protein 750 (ZNF750).

169 e found that the transcript encoding ZFP871 (zinc finger protein 871; also called ZNF709 in humans) i

170 tor for male-specific lethal [MSL] proteins) zinc finger protein binds these GA repeat motifs, increa

171 Here, we report that the CDKN1-interacting zinc finger protein CIZ1 is critical for localization of

172 The zinc finger protein CTCF has been invoked in establishin

173 The role of the zinc finger protein CTCF in organizing the genome within

174 ZNHIT3 encodes a nuclear zinc finger protein previously implicated in transcripti

175 (H2)F1 is an octa-zinc finger protein required for mRNP-gRNP docking, pre-

176 ent study was to analyze in vivo the role of zinc finger protein SNAI1 (SNAI1) on renal fibrosis.

177 Yin Yang 1 (YY1) is a zinc finger protein that functions as a transcriptional

178 Methanol expression regulator 1 (Mxr1p) is a zinc finger protein that regulates the expression of gen

179 Here we identify the uncharacterized zinc finger protein Tmc1 as a dynamically regulated stre

180 Here, we demonstrate that the zinc finger protein Zbtb20 is required for DNL.

181 d a distinct complex containing Mtr4 and the zinc finger protein ZFC3H1.

182 Here, we identify the zinc finger protein Zfp106 as a specific GGGGCC RNA repe

183 Here we show that the nuclear zinc finger protein ZFP106 is highly enriched in skeleta

184 Further analyses of the zinc finger protein Zfp871 and BTB/POZ domain transcript

185 The C2H2-type zinc finger protein ZNF764 acts as an enhancer for sever

186 The zinc finger protein ZPR1 interacts with SMN.

187 s, where the gene of MOZ (monocytic leukemia zinc finger protein) was first identified as a recurrent

188 ted with molecular processes/other proteins, zinc finger protein, intracellular/extracellular enzymes

189 em cell lineage that a spermatocyte-specific zinc finger protein, Kumgang (Kmg), working with the chr

190 We identify another zinc finger protein, Yin Yang 1 (YY1), at the base of lo

191 Here we show that a zinc finger protein, ZIC2, a key regulator for central n

192 c-Myc-interacting zinc finger protein-1 (Miz-1) is a poly-Cys2His2 zinc fi

193 gi apparatus-specific Asp-His-His-Cys (DHHC) zinc finger protein.

194 gi apparatus-specific Asp-His-His-Cys (DHHC) zinc finger protein; (ii) a GODZ dominant-negative mutan

195 e transcription factor Miz1 (Myc-interacting zinc finger protein; encoded by Zbtb17) in mouse Schwann

196 The RNA-binding Zinc-finger protein 106 (ZFP106) detected in both librar

197 nt, which was abolished by deficiency in the zinc-finger protein Bcl11b but restored by IL-25R overex

198 that chromatin neighbourhoods, formed by the zinc-finger protein CTCF, can sequester enhancers and th

199 chains upon protein-DNA association for the zinc-finger protein Egr-1.

200 nucleic acid binding protein (CNBP/ZNF9), a zinc-finger protein known to bind single-stranded G-rich

201 The C2H2 zinc-finger protein Pita binds to several BX-C boundarie

202 The zinc-finger protein tristetraprolin (TTP) binds to AU-ri

203 transcriptional repression, mediated by the zinc-finger protein Zeb2 (also known as Sip1), is essent

204 complex bound to DNA by the ES cell-specific zinc-finger protein ZFP809.

205 scopy and edgetic mutations that the bitopic zinc-finger protein ZitP implements specialized developm

206 rated the target search process of the Egr-1 zinc-finger protein.

207 of decoys on the search process of the Egr-1 zinc-finger protein.

208 Viral-mediated delivery of engineered zinc finger proteins (ZFP) targeted histone H3 lysine 9/

209 matically compared four different engineered zinc finger proteins (ZFP), four transcription activator

210 our known CRBN neo-substrates [Ikaros family zinc finger proteins 1 (IKZF1) and 3 (IKZF3), casein kin

211 ZFNs resulted from basic research on zinc finger proteins and the FokI restriction enzyme (wh

212 ressor complex, which involves multiple KRAB zinc finger proteins, shields neuronal genomes from exce

213 developed DNA-targeting platforms, including zinc finger proteins, transcription activator-like effec

214 tristetraprolin (TTP) family of CCCH tandem zinc finger proteins.

215 Kruppel-associated box zinc-finger proteins (KRAB-ZFPs) make up the largest fam

216 rgeted specifically to Fosb using engineered zinc-finger proteins (ZFPs).

217 n a synthetic guide RNA and DNA, outperforms zinc-finger proteins and transcription activator-like ef

218 myelodysplastic syndrome 1 (MDS)/EVI encode zinc-finger proteins that have been recognized as import

219 longs to the tristetraprolin (TTP) family of zinc-finger proteins, which bind to mRNAs containing AU-

220 ese findings support a role for iron in some zinc-finger proteins.

221 SWI/SNF catalytic subunit (SNF2) translocase zinc finger ran-binding domain containing 3 (ZRANB3).

222 tants demonstrated that mutations within the zinc finger region of ZBTB7A invariably resulted in loss

223 use their RNA-recognition motifs but not the Zinc-finger region for RNA binding.

224 ctic protein-induced protein 1 (MCPIP1) is a zinc-finger RNA binding protein with important roles in

225 PR-domain-containing proteins (PRDMs) are zinc-finger sequence-specific chromatin factors that hav

226 ucose-PKA pathway that inactivates conserved zinc finger stress-resistance transcription factors to s

227 BRPF1 contains a unique assembly of zinc fingers, termed a PZP domain, the physiological rol

228 t genomic occupancy of TBX5, NKX2-5, and the zinc finger TF GATA4 coordinately controlling cardiac ge

229 The zinc finger TF Ikaros, encoded by Ikzf1, is essential fo

230 fbp1 gene, binding of Rst2 (a critical C2H2 zinc-finger TF) is mediated by a local loop structure.

231 hat catalyzes H3K36 demethylation and a CxxC zinc-finger that recognizes CpG islands and recruits the

232 The zinc-finger transciption factor KLF4 is a key driver of

233 ardiac reprogramming, we discovered that the zinc finger transcription factor 281 (ZNF281) potently s

234 Here, we identify the zinc finger transcription factor EGR1 as a negative regu

235 GR1 (early growth response 1), a member of a zinc finger transcription factor family, has been descri

236 Deficiency in Kruppel-like zinc finger transcription factor GLI-similar 3 (GLIS3) i

237 Being itself inducible by ATRA, this zinc finger transcription factor is involved in modulati

238 tion between Drosophila FOXO (dFOXO) and the zinc finger transcription factor Kruppel homolog 1 (Kr-h

239 lar and molecular analyses, we show that the zinc finger transcription factor Kruppel-like factor 3 (

240 ion is regulated through the activity of the zinc finger transcription factor NMP4 (ZNF384, CIZ).

241 gene 3 (Peg3), an imprinted gene encoding a zinc finger transcription factor postulated to function

242 dance with previous studies showing that the zinc finger transcription factor Th-POK is a key negativ

243 f Nestin were mediated by binding to Gli3, a zinc finger transcription factor that negatively regulat

244 GATA3 is a zinc finger transcription factor that plays a crucial ro

245 Here we establish the zinc finger transcription factor Tshz1 as a marker of IT

246 SIGNIFICANCE STATEMENT We show here that the zinc finger transcription factor Tshz1 is expressed duri

247 ZNF322A encoding a classical Cys2His2 zinc finger transcription factor was previously revealed

248 EGR1 is an early growth response zinc finger transcription factor with broad actions, inc

249 Methanol expression regulator 1 (Mxr1p), a zinc finger transcription factor, is essential for growt

250 el-like factor 15 (KLF15), a kidney-enriched zinc finger transcription factor, is required for restor

251 report the functional characterization of a zinc finger transcription factor, OsGATA12, whose overex

252 In this study, we have identified the Ikaros zinc finger transcription factors Aiolos and Ikaros as n

253 mechanism through which STAT3 and the Ikaros zinc finger transcription factors Aiolos and Ikaros coop

254 The rules of engagement between zinc finger transcription factors and DNA have been part

255 romoter luciferase vector, we found that the zinc finger transcription factors early growth response

256 GATA4 and GATA6 are zinc finger transcription factors that have important fu

257 Two proteins comprising the ZEB family of zinc finger transcription factors, ZEB1 and ZEB2, execut

258 Kruppel-like factor 5 (Klf5) encodes a zinc-finger transcription factor and has been reported t

259 (NuRD) complex binding are required for the zinc-finger transcription factor CASZ1 to function as a

260 Here, we identify a zinc-finger transcription factor Hindsight (Hnt) as the

261 We further identify Gata-3, a zinc-finger transcription factor in the dysfunctional mo

262 Kruppel-like factor 4 (KLF4, GKLF) is a zinc-finger transcription factor involved in a large var

263 The Zfp423/ZNF423 gene encodes a 30-zinc-finger transcription factor involved in key develop

264 We demonstrate that the zinc-finger transcription factor MtSTOP is essentially r

265 Here, we show that the zinc-finger transcription factor Nerfin-1 is expressed i

266 Furthermore, hand2 and the co-expressed zinc-finger transcription factor osr1 have functionally

267 osterix (osx; sp7) encodes a zinc-finger transcription factor that controls osteoblas

268 OVOL2 encodes ovo-like zinc finger 2, a C2H2 zinc-finger transcription factor that regulates mesenchy

269 Yin and yang 1 (YY1) is a well-known zinc-finger transcription factor with crucial roles in n

270 Mutations in human zinc-finger transcription factor WT1 result in abnormal

271 We show that Combgap (Cg), a zinc-finger transcription factor, antagonizes Eya-So fun

272 TSHZ3, which encodes a zinc-finger transcription factor, was recently positione

273 s of the specificity protein (Sp) 1/Klf-like zinc-finger transcription factors Sp5 and Sp8 (i.e., Sp5

274 Kruppel-like factors (KLFs) are a family of zinc-finger transcription factors that are found in many

275 bset of luminal progenitors that express the zinc finger transcriptional repressor Blimp1, and demons

276 eviously demonstrated that expression of the zinc finger transcriptional repressor Blimp1/PRDM1 is es

277 Recent experiments demonstrate that the zinc finger transcriptional repressor Prdm1/Blimp1 is es

278 y, transcriptional targets recognized by the zinc finger transcriptional repressor Prdm1/Blimp1, an e

279 ransition (EMT), TGF-beta1 signaling and the Zinc finger transcriptional repressor protein Slug, in v

280 the binding affinity for Klumpfuss (Klu), a zinc finger transcriptional repressor that regulates ss

281 des and RNA interference targeting mRNA, and zinc finger transcriptional repressors and CRISPR-Cas9 m

282 s and virally delivered RNA interference and zinc finger transcriptional repressors in advanced testi

283 finger; however, the promyelocytic leukemia zinc finger transgene does not restore iNKT cell numbers

284 We show that the ubiquitin-binding zinc finger (UBZ) domain of FAN1, which is needed for in

285 if that, together with its ubiquitin-binding zinc finger (UBZ) domain, helps recruit FAN1 to ubiquity

286 Because an Sp7-like zinc finger variant is restricted to vertebrates, the em

287 ome-wide targeting require its four Cys2His2 zinc fingers, which directly recognize a CTCTGYTY motif.

288 TB38 is an under-characterized member of the zinc finger (ZF) family of methyl-CpG binding proteins.

289 n gamma-globin promoter with custom-designed zinc finger (ZF) proteins (ZF-Ldb1), leading to reactiva

290 Polydactyl zinc finger (ZF) proteins have prominent roles in gene r

291 h sequence-specific DNA binding via its C2H2 zinc finger (ZF) tandem array, which is highly polymorph

292 finger protein-1 (Miz-1) is a poly-Cys2His2 zinc finger (ZF) transcriptional regulator of many cell

293 DDS mutations cluster predominantly in zinc fingers (ZF) 2 and 3 at the C-terminus of WT1, whic

294 ctor (CTCF), containing a tandem array of 11 zinc fingers (ZFs), modulates the three-dimensional orga

295 g modules: full-length DNA binding proteins, zinc fingers (ZFs), transcription activator-like effecto

296 ormed by Zn(II) displacement from the parent zinc fingers (ZFs).

297 trate and further show that ZFP91 harbours a zinc finger (ZnF) motif, related to the IKZF1/3 ZnF, cri

298 The multidomain zinc finger (ZnF) protein PRDM9 (PRD1-BF1-RIZ1 homologou

299 mic loci containing a CTCTGYTY motif via its zinc-finger (ZnF) domains and facilitates the recruitmen

300 The NMR solution structure of the zinc-finger (ZnR) domain from the bifunctional and bipol