ライフサイエンスコーパス: zona glomerulosa

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1 e aldosterone-secreting cells of the adrenal zona glomerulosa.

2 ost cells and maintain the properties of the zona glomerulosa.

3 functional role of genes upregulated in the zona glomerulosa.

4 day) inhibits AT(1) binding in adrenal gland zona glomerulosa and kidney glomeruli.

5 ceptors (AT(1)Rs), present in adrenocortical zona glomerulosa (AZG) cell membranes.

6 produced and secreted by the adrenocortical zona glomerulosa (AZG) cells after angiotensin II (AngII

7 eptides on aldosterone generation in a human zona glomerulosa cell line, H295R.

8 Zona glomerulosa cells (ZG) of the adrenal gland constan

9 as accompanied by marked increase in adrenal zona glomerulosa cells and adrenal P450aldo mRNA.

10 inding of angiotensin II to its receptors in zona glomerulosa cells was demonstrated.

11 ts reproduced modulation observed in adrenal zona glomerulosa cells.

12 t and cell-attached patches from rat adrenal zona glomerulosa cells.

13 at were at least five times overexpressed in zona glomerulosa compared with zona fasciculata.

14 ssociated with a pattern of decreased normal zona glomerulosa CYP11B2 expression and increased aldost

15 these adenomas, composed of cells resembling zona glomerulosa, have mutations in genes ATP1A1 and CAC

16 We performed exome sequencing of ten zona glomerulosa-like APAs and identified nine with soma

17 disruption of this signaling complex in the zona glomerulosa may provide a new therapeutic approach

18 is one of the most highly expressed genes in zona glomerulosa of the human adrenal gland.

19 One of the most zona glomerulosa-selective genes was ANO4, a member of t

20 s in situ and in cells of the native adrenal zona glomerulosa stimulated by Ang II in vivo.

21 ANO4 was 19.9 times higher in zona glomerulosa than in zona fasciculata (p=6.6 x 10(-2

22 derstand whether the adenomas originate from zona glomerulosa, we carried out a microarray analysis c

23 ntial for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona

24 c layers that develop postnatally, the outer zona glomerulosa (zG) and the inner zona fasciculata (zF

25 nenolone, and progesterone in bovine adrenal zona glomerulosa (ZG) cells.

26 erproduction of aldosterone from the adrenal zona glomerulosa (ZG) is also the most frequent cause of

27 tome with conventional adrenocortical zones [zona glomerulosa (ZG), zona fasciculata, and zona reticu

28 Zona glomerulosa (ZG)-like APAs frequently have mutation

29 roarray analysis comparing transcriptomes of zona glomerulosa, zona fasciculata, and tumour in human

30 Wycombe, UK), we compared transcriptomes of zona glomerulosa, zona fasciculata, and tumour obtained

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