ライフサイエンスコーパス: zygotene

1 juxtaposition at centromere regions at early zygotene.

2 ENs per unit length of SC from early to late zygotene.

3 and progresses along chromosome arms during zygotene.

4 The nucleolus was adjacent to the cluster at zygotene.

5 The telomere cluster persisted throughout zygotene and into early pachytene.

6 permatocytes were arrested between leptotene/zygotene and pachytene and died through apoptosis.

7 Chk1 accumulates in late zygotene and pachytene spermatocytes and is present alon

8 te foci along meiotic chromosomes during the zygotene and pachytene stages of meiosis.

9 form on the chromosomes at the beginning of zygotene and rise to approximately 500 per nucleus by mi

10 ly with chromatin loops during leptotene and zygotene and showed preferential binding in the vicinity

11 a peak at day 14 postpartum, when leptotene, zygotene, and early pachytene spermatocytes are the most

12 mologous chromosomes at late leptotene/early zygotene are essential steps before chromosome synapsis

13 During zygotene, as homologous chromosomes pair and synapse, a

14 et, then the meiotic-vegetal center forms at zygotene bouquet stages, when symmetry is, in effect, br

15 ame process, in modulated form, explains the zygotene "bouquet" configuration in which, immediately p

16 cells at early meiotic stages (leptotene and zygotene) but lower percentages at later stages (pachyte

17 es of subtelomeric synapsis emerged at early zygotene, centromere clusters lost their strong polariza

18 tes the transition through a novel leptotene-zygotene checkpoint, a key step in early meiotic prophas

19 ant decreases in the number of RAD51 foci at zygotene, corresponding to the degree of their pairing d

20 At late zygotene/early pachytene a proportion of AtMSH5 foci co-

21 At the late zygotene/early pachytene transition, about one-third of

22 on events are independent of the earlier mid-zygotene events, whereas both mid and late synapsis init

23 ularly enriched during meiotic leptotene and zygotene in germline chromatin of Tetrahymena and C. ele

24 Chromosome synapsis during zygotene is a prerequisite for the timely homologous rec

25 The tight bouquet normally seen at zygotene is a rare event.

26 Leptotene and zygotene (L/Z) spermatocytes are not competent to respon

27 (Hordeum vulgare) to only 2 to 17% of normal zygotene levels.

28 arly euchromatic SC initiation events at mid-zygotene may be required for DSBs to be repaired as cros

29 We further reveal that in zygotene nests, intercellular cytoplasmic bridges remain

30 tonemal complexes (SCs) during leptotene and zygotene of meiosis.

31 In "late zygotene" oocytes, SC initiates at many more sites that

32 In "mid-zygotene" oocytes, SC initiates at several euchromatic s

33 In "early zygotene" oocytes, synapsis is only observed at the cent

34 ls enter meiosis but fail to progress beyond zygotene or leptotene stage.

35 Meiosis is arrested at the zygotene/pachytene stage of prophase I as a result of ab

36 erature-sensitive failure of meiosis in late Zygotene/Pachytene that is associated with defective for

37 c prophase I when it regulates the leptotene-zygotene progression.

38 on the frequency and distribution of ENs in zygotene SC spreads from six plant species that include

39 nvolution light microscopy revealed that, at zygotene, SC assembly was initiated at foci that appeare

40 sion of interstitial ZYP1 loci elongating at zygotene so synapsis at centromeres is a continuation of

41 s of normal mice, where only a few leptotene/zygotene spermatocytes I with clustered telomeres were d

42 ity that are initially detected in leptotene-zygotene spermatocytes just preceding the formation of t

43 of DNA breaks detected rose as leptotene and zygotene spermatocytes populate the testis with a peak a

44 oteins in enriched preparations of leptotene/zygotene spermatocytes, prepubertal and adult pachytene

45 her localize cyclin B3 mRNA to leptotene and zygotene spermatocytes.

46 e that mei1/mei1 spermatocytes arrest at the zygotene stage of meiosis I, exhibiting failure of homol

47 Tdrkh mutants display meiotic arrest at the zygotene stage, attenuate methylation of Line1 DNA, and

48 ck end labeling, and Rad51) at the leptotene/zygotene stages of spermatocytes.

49 genes that are markers for the leptotene and zygotene stages, but not genes that are markers for the

50 Surprisingly, late zygotene synapsis initiation events are independent of t

51 ocalize to the bouquet; and (c) beginning at zygotene, the behavior of telomeres is dominant over any

52 During zygotene, the largest foci were present in regions under

53 xpressed in the germ line of the testis from zygotene through round spermatids, whereas mUtp14a, alth

54 ed ask1 defects in cohesin distribution from zygotene to anaphase I.

55 und to form discrete nuclear foci from early zygotene to late pachytene.

56 nsiently form a cluster during the leptotene/zygotene transition (bouquet arrangement).

57 s associate with the NE during the leptotene-zygotene transition but cluster slowly if at all as meio

58 s. telomeres in the nucleus at the leptotene-zygotene transition is the same in mutant and wild-type

59 maintenance of homolog bias at the leptotene/zygotene transition of meiotic prophase.

60 type (WT) meiosis during late leptotene and zygotene, was missing in the ask1-1 mutant.

61 UMO-1 appeared on gonosomal chromatin during zygotene when chromosome homologues pair and sex chromat

62 rise to approximately 500 per nucleus by mid-zygotene when chromosomes are pairing and synapsing.