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1 n a per nuclear basis in myofibers diminishes, which accounts for both the absolute reliance developi
2 nd geological viability of these Xe-Fe oxides, which advance fundamental knowledge for understanding
3 tium (ICGC) and The Cancer Genome Atlas (TCGA), which aggregated whole-genome sequencing data from 2,
5 ide polymorphisms was applied to 290 isolates, which allowed us to identify 25 additional cases relat
6 ural A, T, G and C bases during DNA synthesis, which allows for labeling of replicating or repaired D
7 CPE-K OECTs operate in the accumulation mode, which allows for much lower energy consumption in comp
8 gypsum are formed as secondary mineral phases, which allows for oxyanion partitioning, e.g., IO(3)(-)
9 olecular inputs into generic output sequences, which allows for the target recognition and signal gen
11 eta power during rest and movement in the GPi, which also had more beta desynchronization during move
12 coincident with rhythmic Purkinje cell firing, which alters the activity of their target cerebellar n
13 rk of MS diagnosis is the presence of IgG Abs, which appear as oligoclonal bands in the cerebrospinal
14 sociated with autobiographical recall periods (which are insensitive to the moment-to-moment content
15 70 S cm(-1) ) and high work function (~5.1 eV), which are achieved by combining a simple solution pro
17 .015 (Cd), 0.021 (Hg) and 0.105 (Pb) mug g(-1), which are suitable to attain the maximum levels recom
20 ed evidence of higher TCR-transmitted signals, which are also characteristics of recent thymic emigra
22 y of ~15 100 S cm(-1) for a 214 nm thick film, which are both the highest values compared to previous
23 purious and deleted cut sites in the raw data, which are called Rmaps, make assembly and alignment of
25 rauterine growth restriction and preeclampsia, which are characterized by uteroplacental ischaemia an
27 ivatives is to discover highly stable cations, which are further integrated to construct metallo-poly
28 rowth of other noble-metal-based delafossites, which are known to be challenging due to the difficult
29 rminal endings of primary nociceptive neurons, which are organized into morphologically complex termi
30 mage leading to demyelination and axonal loss, which are pathological features of multiple sclerosis
31 ntacts with the composite Phactr1/PP1 surface, which are required for efficient dephosphorylation.
33 ons in A25 had a heightened density of NMDARs, which are the targets of novel rapid-acting antidepres
34 ces truncated CD19 expression in solid tumors, which are then eradicated by CD19-specific CAR-T cells
35 , small sample size, and possible recall bias, which are typically associated with studies of patient
36 ponents involved in nanoparticle formulations, which are utilized in delivery platforms for RNA thera
37 mpatibility of these functionalized nanotubes, which are wrapped by encapsulation agent (phospholipid
38 e isolated in the reinforcer devaluation task, which assesses the ability to infer the current value
40 ondary anionic lipid site has been identified, which augments the activation by PIP(2); and cholester
41 bined site 3 substitutions of W156A and L160E, which become buried at the complex interface, disrupt
42 segregation is controlled by the MatP protein, which binds to specific sites (matS) within ter, and i
43 intrinsic negative regulator of inflammation, which broadly attenuates pro-inflammatory gene program
44 imaging with chest radiography and ultrasound, which can also be used to assess the lung parenchyma,
45 he key diazatitanacyclohexadiene intermediate, which can be accessed via multicomponent coupling of T
46 ales at different regions of the flow network, which can be classified into flowing and stagnant regi
47 aintenance of ipsilateral projections of CSNs, which can form functional connections with spinal neur
48 nt insights about the cause of these diseases, which can help accelerate new prevention strategies.
49 ebiotically plausible xenobiological monomers, which can hydrolytically interconvert between cyclic a
50 fluences the biological activity of chitosans, which can now be recognized as bona fide information-c
51 le ligand binding sites or modification sites, which can operate to create an ultrasensitive dose res
53 on can explain phenotypes of genetic diseases, which cannot be obtained by transcript information alo
55 toyltransferase (NMT) is an essential protein, which catalyzes the myristoylation of protein substrat
56 dule) to introduce intercrystal light sharing, which closely mimics the behavior of dual-ended readou
58 etic 2D CCFs for electrochemical applications, which concerns novel monomer design, chemical methodol
60 tal opening and closing across the diel cycle, which conserves water and provides a means of maintain
62 on were compared against a reference scenario, which consisted of mobile colocation measurements with
63 t only occurs among closely contact ion-pairs, which constitutes the rationale behind the "water-in-s
64 lveolar bone by the periodontal ligament (PDL), which contains stem cells supporting tissue turnover.
65 atal encephalitis in humans and other mammals, which continues to present a public health threat in m
66 odifies the composition of the gut microbiome, which contributes to the metabolism of flavonoids.
67 ble temperature-dependent molecular mechanism, which contributes to the robustness of TC through natu
69 ence of Munc18-1, Munc13-1, NSF and alphaSNAP, which coordinate the assembly-disassembly cycle of neu
70 polyploidy induces recombination suppression, which correlates with altered epigenetic landscapes an
71 viral loads are followed by rapid elimination, which could be coupled with cytokine expansion and con
72 have an unnoticed fah1-2 background mutation, which could cause salicylic acid- and EDS5-independent
73 gions promoting myosin interaction with actin, which could explain the observed delays in the onset o
74 us antibiotics may face barriers to discharge, which could prolong hospital length of stay (LOS) and
75 hnical approach to improve the charge density, which could push the output performance of TENG to a n
76 tions of (un)binding pathways of TSPO ligands, which could reveal the molecular interactions governin
77 ac hypertrophy and impaired systolic function, which could severely limit the therapeutic potential o
78 lication in the oncogene nucleophosmin (NPM1c), which creates a neoepitope presented by the human leu
79 s) develop in patients with chronic hepatitis, which creates a microenvironment for the growth of hep
80 DENV-2 NS1-specific IgG in naive individuals, which cross-reacted with DENV-1, -3, and -4 NS1 to var
81 15.2 mmHg (standard deviation [SD], 3.4 mmHg), which decreased to 14.2 mmHg (SD, 3.0 mmHg) at 12 mon
82 etween genotypes and pollination time as well, which demonstrated high performance of the metabolic f
83 sured using Forster resonance energy transfer, which detects nanodomains as well as large domains.
85 are the cornerstones of synthetic strategies, which directly provides the direct molecular-based des
86 y plastic hybrid epithelial/mesenchymal cells, which display invasive features and alterations in met
87 a brain-permeable EP2 antagonist 1 (TG6-10-1), which displayed anti-inflammatory and neuroprotective
88 location tool to handle kinematic constraints, which enable modeling of kinematic loops (e.g., cyclin
90 13), as well as a novel candidate gene (ILDR1), which encodes a receptor highly expressed in prostate
91 e Mid-UP period (MUP, 33,000-24,000 years ago), which encompasses a pan-European cultural mosaic (Gra
93 ation or enrich for p38-YAP-TEAD interactions, which explains the topography-dependent diversity in f
94 effects are favored in arcs with thick crust, which explains why magmatism and differentiation in co
96 ved very high currents of tens of nanoamperes, which flowed through both homogeneous and non-homogene
97 es two functional proteins, MOCS1A and MOCS1B, which follow different translocation routes before mit
98 d deeper integration with the Ensembl project, which forms a key part of our future strategy for deal
101 The central node of this network is G3BP1, which functions as a molecular switch that triggers RN
102 llow a longitudinal design to collect samples, which further complicates the analysis methods needed.
103 rstone in I/R-related endothelial dysfunction, which further impairs local microcirculation with a fe
106 with Shewanella for syntrophic electrogenesis, which grants the system additional flexibility in conv
107 ently broken motif was REST (p value = 0.0028), which has been reported as both a tumor suppressor an
108 c fork protection complex (Csm3/Tof1 and Mrc1), which has important roles including aiding normal rep
109 to treat triple negative breast cancer (TNBC), which has poor prognosis due to frequent metastasis.
110 M)-1 are biomarkers of endothelial activation, which has been implicated in the pathogenesis of heart
111 rats to perform object-context discrimination, which has been proposed to require temporoammonic inpu
113 tropomyosin receptor kinase (TRK) A, B, and C, which has been shown to have anti-tumour activity agai
114 th the same cell type in somatosensory cortex, which has important implications for our understanding
115 bunit of the chromatin remodeling BAF complex, which has known contributions to developmental process
116 experiments can be time-consuming and costly, which has led to the development of programmes for per
117 ate effector binding from biological function, which has ramifications for riboswitch characterizatio
120 Bright lead halide perovskite nanocrystals, which have been extensively studied in the past 5 year
121 healthy BALB/c mice (controls) and TxA23 mice, which have chronically inflamed stomachs with metaplas
122 ious types of laminopathy-containing diseases, which have features of accelerated aging and osteoporo
123 ons derived from human pluripotent stem cells, which have several advantages over fetal cell-derived
124 tensity of hypoxic events in the coastal zone, which have the potential to affect marine biodiversity
125 st majority of sequences were small fragments, which highlights the challenge of assembling viral gen
126 fitness-related traits and demographic rates, which in herbivores are often linked to resource-drive
127 e functions are both mediated by Scc1-cohesin, which in mitosis is released from chromosomes by Wapl
128 ase, leading to increased expression of c-Myc, which in turn stimulated a pathological gene program.
129 The wells are seeded with cell-laden collagen, which, in response to the gradual slope of the circumf
130 ns among challenges in high-elevation streams, which include low but rising temperatures, low oxygen
131 ed by histoPathology Reports in Sweden) study, which included gastrointestinal pathology reports from
133 Obstructive sleep-disordered breathing (SDB), which includes primary snoring through to obstructive
135 with production, trade, and mislabeling data, which increase the uncertainty surrounding seafood mis
136 extrapulmonary invasion and damage is likely, which indeed has already been demonstrated by cardiova
137 d-of-life care expenditures than site COC did, which indicated significant care coordination gaps wit
138 oup III gadolinium-based contrast agent (GBCA), which indicates that there are limited data regarding
139 rossbar arrays for the implementation of CNNs, which integrate eight 2,048-cell memristor arrays to i
140 Bayesian Inference of Regulatory Differences, which integrates prior information and explicitly acco
141 s are also observed during grasping movements, which involve fundamentally different patterns of kine
142 ted using nanoparticle tracking analysis (NTA), which is a widely used technique for determining the
143 from that of Johanson-Blizzard syndrome (JBS), which is caused by bi-allelic variants in UBR1, notab
144 d density in solution of 1.03 +/- 0.02 g/cm(3), which is much lower than those reported or assumed in
145 ing ability in patients with corneal diseases, which is a crucial part of visual rehabilitation.
146 derived from wastewater microbial communities, which is a major impediment for the design of sustaina
147 (1-NMN), creatinine, carnitine, and metformin, which is a probe for OCT1 and OCT2 and MATE1 and MATE2
148 introduces the concept of synthetic datasets, which is an emerging method originally developed to pe
149 less is known regarding the afferent synapse, which is an essential component in the faithful tempor
150 uncertainty is partly due to parameterization, which is an essential procedure for model specificatio
151 ve diseases that share a common genetic cause, which is an expansion of CAG repeats in the coding reg
152 and MKK5, or YDA show a short-root phenotype, which is associated with reduced mitotic activity and
153 are mediated by its flat DNA-binding surface, which is centered on a short loop spanning K61 to I72
155 ctions and are absent in the main input layer, which is consistent with a laminar processing hierarch
156 le epidemiologic data collection and analysis, which is critical for a data-driven response to this p
157 simple battery configuration and high safety, which is different from traditional molten-salt Li met
158 d treatment effects by using the hazard ratio, which is difficult to interpret for a positive event,
159 h serrated structures on the millimeter scale, which is distinct from that on a conventional planar s
160 17 development and tissue-specific imprinting, which is essential for infection and autoimmunity.
161 hanisms are postulated, both triggered by HBr, which is evidenced also to take part in the Z/E isomer
162 triggers a hierarchy in substrate utilization, which is facilitated by changes in protein abundances
163 r will promote N(2) O and ammonium production, which is generally not desirable in engineered systems
164 of this study include potential missing data, which is in part addressed by the use of cross-matched
165 offspring is induced by meiotic recombination, which is initiated between homologs at >200 sites orig
166 associated with poorer CRC-specific survival, which is most pronounced in cases carrying TP53 mutati
167 and (3) evergreen trees had the deepest roots, which is necessary to maintain canopy during simulated
168 tudents to relocate or be available full time, which is not feasible for students who have family, wo
170 enSim Moco uses the direct collocation method, which is often faster and can handle more diverse prob
171 ma (CCA) is its poor response to chemotherapy, which is partly due to reduction of intracellular leve
172 g ecosystem-wide multitrophic complementarity, which is potentially an important prerequisite for the
173 losum exhibits substantial atrophy in old age, which is stronger than what would be predicted from pa
174 As a result, ROS-mediated protein damage, which is substantial during the aging of short-lived m
176 luminescent europium chelate-conjugated probe, which is the key component in sensing the hydrophobic
177 ate proteomes in a proteoform-specific manner, which is vital for accurately understanding protein fu
178 ted with increased rates of protein synthesis, which lead to growth inhibition and hypersensitivity t
179 ies of adipose tissues and their dysfunctions, which lead to several metabolic diseases including obe
180 and reliability of gene expression estimation, which lead to the improved downstream gene expression-
181 the site-selective oxidative etching of Au(0), which leads to nonuniform growths along different lat
183 ed greater IPA compared with chewed prasugrel, which led to higher active metabolite concentration bu
184 r TIRS, the best strategy was threshold-based, which led to the fewest infections of all strategies t
185 chanical activation of p38-YAP-TEAD signaling, which likely contribute to myofibroblast heterogeneity
187 sis of these insights, we created trametiglue, which limits adaptive resistance to MEK inhibition by
189 it in observational learning remained unknown, which limits our chances to improve intergroup learnin
190 opulation at a cost of under $100 per patient, which makes this combination suitable for elimination
191 0-20% of these patients is lineage plasticity, which manifests in a partial or complete small cell or
192 cy (V(O) ) concentration and Ti(3+) formation, which markedly improves the electrocatalytic NRR perfo
194 grunt black margate (Anisotremus surinamensis), which may be exerting top-down pressure on C. abbrevi
195 nd to diseases vary widely across individuals, which may be partly due to baseline immune variations.
196 some abnormal alignment in the upper quarter, which may contribute to the dysfunction of the cervico
197 reduced muscle mass that persists postnatally, which may contribute to their increased risk for adult
200 lation may alter the state of the environment, which may in turn feedback to change the incentive str
201 ood vaccinations during the COVID-19 pandemic, which may leave communities more vulnerable to vaccine
202 in tissue remodelling and repair after injury, which may partly underpin its association with OA risk
203 manipulate 3D graphene electrical properties, which may pave a new way to design new 3D graphene dev
204 ence for potential, SIB-specific FC signature, which may point to compensatory neurofunctional mechan
205 opathy-associated genes in patients with HLHS, which may portend impaired functional reserve of the s
206 ated arginolysis and glycolysis, respectively, which may provide insights into understanding miRNA si
207 on membrane structure and physical properties, which may provide some clues to understanding how mela
209 gular, equidistant spacing of ovule primordia, which may serve to minimize competition between seeds
211 ns, such as the thalamus and brainstem nuclei, which mediate complex interactions with the brain's co
212 ew functionalities of the genomic expressions, which might be dormant in a single-source analysis.
213 ortantly, connectivity is impaired by insults, which mimic the diabetic milieu, including high glucos
215 ized excitonic processes available in 2D COFs, which motivate their continued design and implementati
216 of-transfer (oriT) sequence as the relaxosome, which nicks the DNA strand destined for transfer and c
217 ctive particulates in subglacial environments, which play a key role in trace elemental cycles, with
218 Ca(2+)-dependent cell-cell adhesion proteins, which play essential roles in animal evolution, tissue
219 dolphin (GRD, Platanista gangetica gangetica), which plays a significant role in maintaining the str
220 human PC4, the prototype of PC4-like proteins, which plays roles in transcription and maintenance of
223 alphaSN is an abundant protein in the CNS, which potentially could overwhelm clearance of cytotox
224 ge-reaction-based biochemical circuit cascade, which probes a specific biomolecular input, transform
225 ns a particularly acute problem for triploids, which produce desirable seedless watermelons, but show
226 m of CIN is the overproduction of centrosomes, which promotes tumorigenesis in various mouse models.
228 ic polymer, conjugated with indocyanine green, which rapidly and irreversibly dissociates to fluoresc
229 nt signal emitted from single-molecule probes, which rapidly degrades resolution with increasing dept
231 e rapidly infiltrated by recipient leukocytes, which recapitulated the liver myeloid and lymphoid com
233 Initially, corrosion etch pits are formed, which reflect the local symmetry of the surface: squar
234 ation but impaired eyeblink conditioning (EBC), which relies on the ability to establish associations
235 ng the clinical effectiveness of beta-lactams, which remain first-line antibiotics for many infection
237 Generated MDSCs displayed a glycolytic switch, which rendered them more susceptible toward glycolytic
238 ling by freshly isolated human CD8(+) T cells, which represent a challenging but valuable model to ga
240 nition, disassembly, and degradation by ClpC1, which requires disordered ends in its protein substrat
242 after enzyme immobilization on the glass bead, which seemed to be related to the polyaldehyde kefiran
243 onic and steric nature of the sulfonyl moiety, which serves as a base-labile protecting group and con
244 the combination of belatacept and PI therapy, which significantly reduced both class I and II HLA an
245 dox waves with a low electrochemical band gap, which signifies the tuning of highest occupied molecul
246 uction in late January or early February 2020, which subsequently spread locally before active commun
247 ted the discovery of a new Ti(salen) catalyst, which substantially expanded the reaction scope and si
248 biomass but not to physical mixing processes, which suggests a potential role of vertical transport
249 sion of mouse lipin-2 is catalytically active, which suggests mammalian lipins function with the same
250 thout inducing alcohol dehydrogenase activity, which suggests that coated fruit did not ferment.
251 dults, but diet soft drink consumption is not, which supports the need to strengthen existing recomme
252 cated that these metabolites bind ferric iron, which suppresses their production when added to the gr
253 nism requires aconitate decarboxylase 1 (IRG1), which synthesizes itaconate, a metabolite with antimi
254 uitment process for the target clinical trial, which then can be used for augmenting the information
255 ng IRE1alpha blocked stellate cell activation, which then decreased proliferation and migration of tu
257 mechanism wherein 5-AzadC induced DNA damage, which then resulted in enhanced occupancy of NF-kB, P-
259 ell activation, differentiation, and function, which translates in vivo to an improved ability for T
260 f a borirane-borane intermediate are isolated, which upon further reduction give rise to the aforemen
263 ciated by consumers for its sensorial profile, which varies depending on the flora used by the honeyb
265 ed Stem Cell Inhibitory RNA Transcript (SCIRT), which was markedly upregulated in tumorspheres but co
266 nd hepatocytes LPS localization than controls, which was correlated with serum zonulin and phosphoryl
267 enesis was nearly absent in the dentate gyrus, which was due to inhibited proliferation of neural ste
268 t allergenic peptides on the surface of CpCP3, which was highly susceptible to digestive enzymes and
269 mor activity in vivo but was poorly tolerated, which was hypothesized to be the result of undesired l
270 e kidney injury in 32 of 116 (27.6%) patients, which was mostly evident at admission (24/32, 75%).
271 coincided with reduced dopamine neuron firing, which was not observed during antipsychotic efficacy.
272 holinergic axons was sufficient to induce LTP, which was prevented by chelating postsynaptic Ca(2+) o
275 es had a preexisting mental illness diagnosis, which was strongly associated with worse postoperative
278 led receptor (GPCR) kinase interactor 1 (GIT1), which we found to play an unexpected stimulatory role
279 astic kinesiology tape across the knee joints, which we attribute to the presence of intact cutaneous
281 directly infer the coupled electron transfer, which we find to be on the order of 0.1 electron per p
282 t composed of novel fibril-like substructures, which we identify here by three-dimensional single-mol
283 on leads to an elevated quasiparticle density, which we predict would ultimately limit the coherence
285 r signals colocalized with EGFP(Vgat) neurons, which we validated by in situ hybridization for Vgat m
287 ptogenetic responses and network oscillations, which were consistent with ultra-sparse intrinsic conn
288 silicic acid and gelation of silica particles, which were less intrusive and had a milder effect on m
290 l, the database contains 13 494 603 enhancers, which were obtained from 16 055 datasets using 12 high
291 0.61-4.7; P = 0.013) than the lowest quintile, which were significant independently after accounting
292 ns zona occludens-1, claudin-1, and claudin-5, which were significantly reduced after heme exposure.
293 e separation of phenolic acids and flavonoids, which were subsequently detected by a sensitive chemil
295 e structural characteristics of this molecule, which will provide important insights into its functio
296 lass, metal ion and metal-containing cofactor, which will serve as a valuable, integrative data sourc
297 tic tool for AD, regardless of clinical stage, which would be of great benefit in clinical practice a
298 prove graft survival after SL transplantation, which would encourage programs to opt into splitting m
300 of PFOA and PFOS by polyDADMAC-stabilized PAC, which yielded Freundlich adsorption coefficients of 15