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1 nal regulators are transposable elements (TEs), whose aberrant usage could contribute to oncogenic tr
2 1 is highly expressed by alveolar macrophages, whose abundance correlates with pathology and activati
5 new optical biometers, formulas, and methods (whose accuracies have yet to be completely tested) hav
6 acts with ubiquitin-specific protease 8 (USP8), whose activating mutations underlie human tumorigenes
8 on of calcium-activated BK potassium channels, whose activation depends on their tight association wi
9 interactors are switch genes including PRDX4, whose activation strongly correlates with the activati
10 skin is exclusively innervated by GRP fibers, whose activation via optogeneics and chemogenetics in
11 ecies, including humans, machines, and robots, whose activities are associated with large mechanical
12 use of covalently reactive beta5i inhibitors, whose activity against the constitutive proteasome (c-
13 with a DNA-cleaving restriction enzyme, SmaI, whose activity degraded the droplets, causing them to
14 ns are governed by the master regulator tra-1, whose activity is controlled by chromosomal sex and is
15 to their counterparts in somatosensory cortex, whose activity is driven primarily by afferent inputs
16 tering its affinity for the phosphatase Cdc14, whose activity is essential for mitotic exit and compl
17 c inputs from context-responding vCA1 neurons, whose activity was required for contextual fear learni
18 c transition temperature (T(NI) ) are created, whose actuated shape can be locked-in via high-tempera
19 the liquid core to be HSP70 family chaperones, whose adenosine triphosphate (ATP)-dependent activity
20 opment of renewable and unconventional energy, whose adoption is aimed at stemming the impacts of glo
21 hout calcific tendinopathy with shoulder pain, whose age, sex, and shoulder laterality values were ma
22 hanism of the Amyloid beta (Abeta) 42 peptide, whose aggregation intermediates are thought to be one
23 atform affords thermoresponsive bioconjugates, whose aggregation is solely controlled by the polymer
24 modeling and a global optimization algorithm, whose aims are to (1) predict the emergent dynamical b
25 yl)-2,4,6-trihydroxy-3(2H)-benzofuranone (BZF), whose antioxidant potency is notably higher than the
26 Under this scenario, interferon (IFN) beta-1a, whose antiviral potential is already known, and which
27 rdered growth of CN V sensory and motor axons, whose appropriate targeting is critical for optimal S/
29 regeneration rely on resident stem cells (SCs), whose behaviour is regulated through niche-dependent
30 able paclitaxel-based microtubule stabilisers, whose binding is induced by photoisomerisation to thei
31 eries of designed analogues of disorazole B(1), whose biological evaluation led to the identification
32 ns modulating the membrane of excitable cells, whose biological correlates are assessed at electrophy
34 homocitrate] species designated FeMo-cofactor, whose biosynthesis and insertion requires the action o
36 d and orthotopically sutured to the recipient, whose bladder above the ureteral opening level was rem
37 anochamber (DNC), a hollow cuboid nano-object, whose bonds can be fully prescribed and complexly enco
38 ous collections of patient health information, whose broad adoption provides clinicians and researche
39 nisms and we apply it to the HCN4 ion channel, whose cAMP-binding domain is an archetypal conformatio
40 enetic variants, each with very small effects, whose causal effects could not be individually identif
41 uterus is provided by spinal afferent nerves, whose cell bodies lie predominantly in thoracolumbar d
42 icrostructural features of distorted olivines, whose chemical composition is distinct from undistorte
43 ystals (LCs) are omnipresent in living matter, whose chirality is an elegant and distinct feature in
44 infection and room air oxygen saturation <=94% whose clinicians requested remdesivir through the comp
46 ming remarkably strong, hierarchical clusters, whose cohesion derives from grain size rather than min
47 in congenitally (or early) blind individuals, whose color knowledge can only be obtained through lan
50 an VIP1R bound to PACAP27 and Gs heterotrimer, whose complex assembly is stabilized by a NanoBiT teth
51 ously by genetically encoded molecular clocks, whose components cooperate to generate cyclic changes
52 on intermediate beta-glucose 1,6-bisphosphate, whose concentration depends on the beta-glucose 1-phos
53 italized patients (excluding those in the ICU) whose condition reached the alert threshold at hospita
54 ps of the assembly of the pterosaur body plan, whose conquest of aerial space represents a remarkable
55 cell-type-specifying transcriptional circuits, whose constituent genes featured exceptionally high ra
56 modelling to demonstrate that inhibitor pairs, whose constituents adopt distinct mechanisms of haemat
57 ontain appreciable levels of other flavonoids, whose content increases under post-harvest heat treatm
58 ne carbonyl oxygen of an adjacent alpha-helix, whose contribution to inhibitory potency illustrates t
59 ughlin of visual neuroscientist Horace Barlow, whose contributions to the understanding of brain func
60 ates(6) and act as unique Hubbard systems(7-9) whose correlated electronic states can be detected and
61 ditionally used for fibre and seed production, whose cultivation is permitted in Europe for varieties
62 here that loss of the MutLalpha subunit MLH1, whose defect is responsible for ~50% of dMMR cancers,
63 l egress requires two proteins, NPC1 and NPC2, whose defects are responsible for Niemann-Pick disease
64 l regulator 1 (FMR1), a brain-enriched RNA-BP, whose deficiency leads to Fragile X Syndrome (FXS), th
65 B cell-intrinsic checkpoints TRAF3 and TRAF2, whose deletion in B cells enables the BCR to induce CS
66 revealed MRX6, a largely uncharacterized gene, whose deletion resulted in a marked increase in mtDNA
69 n important barttin palmitoyl acyltransferase, whose depletion affected barttin palmitoylation and Cl
70 identified the little studied ZRANB2 and SYF2, whose depletion partially reversed doxorubicin resista
71 expression, including a novel regulator, USF2, whose depletion significantly down-regulated HOXA9 exp
73 f the material had an intrinsic flow velocity, whose direction is dictated by the relative phase betw
74 rned stochastically with stereotyped saccades, whose direction was biased upwind by the timing of pri
75 controlled by inhibitory networks in the PFC, whose disruption is thought to contribute to mental he
76 ears remarkable homology to the Usher complex, whose disruption results in the sensory disorder type
79 tial tumor suppressor for human kidney cancer, whose downregulation is correlated with YAP activation
80 s-mitigating role and mechanism of TDP-43 NBs, whose dysfunction may be involved in ALS pathogenesis.
81 the use of the chemical inhibitor importazole, whose effects are partially rescued by the GTP hydroly
82 ntidepressant with immune-modulatory activity, whose effects on ligature-induced periodontitis are ye
83 s been speculated that the earliest ribozymes, whose emergence marked the origin of life, were low in
85 timulation induces YAP activation through FAK, whose encoding gene, PTK2 is frequently amplified in C
86 er - like deep level has also been identified, whose energy lines up instead on a fixed level across
88 e, we report a new substrate, hydrofurimazine, whose enhanced aqueous solubility allows delivery of h
92 ass of power transfer system, based on a wave, whose existence has been fiercely debated for over a c
93 ase precipitated within the martensitic phase, whose existence was, in turn, understood through predi
94 trol is tightly tied to the prefrontal cortex, whose expansion in humans relative to other species is
95 example of non-equilibrium physical chemistry, whose explanation and understanding still capture the
96 of many genes (36, 13, 25 and 17 respectively) whose expression are also altered in CC, PC, LC and GC
97 t the nuclear lamina filament Lamin B2 (Lmnb2), whose expression decreases in mice after birth, is es
98 genic cue, fibroblast growth factor 15 (FGF15), whose expression in the visual thalamus is regulated
99 tly mediated by FOXM1, which regulates LIN28B, whose expression also correlates with clinical prognos
100 une markers, in contrast with sulfonated HMOs, whose expression correlated with suppression of two ma
101 rough map-based cloning and association study, whose expression in fruit phloem is associated with ac
103 developmental trajectories of leaf allometry, whose expression is contingent heavily upon the enviro
104 scription factor genes, SlWRKY22 and SlWRKY25, whose expression is increased during Pst-induced ETI.
105 EBV posttranscriptional regulator protein SM, whose expression is limited to the replicative cycle.
106 tolerance is a metabolically expensive trait, whose expression is restricted to thermoneutral mice a
107 irectionally from active regulatory sequences, whose expression levels correlate with enhancer activi
108 t of SCZ and linear HOMER1 mRNA were observed, whose expression was mostly unaltered in BD and SCZ po
109 hers across bird species except silent fliers, whose feathers also lack the associated Velcro-like no
110 n parameters from many experimental variables, whose features are usually hidden in the high-dimensio
111 his is particularly true for large carnivores, whose fine-scale monitoring is logistically complex an
112 e a novel neuron type, vector trace cell (VTC), whose firing generates a new vector field when a cue
113 t using exquisite force sensors such as talin, whose folding status triggers mechanotransduction path
114 migration is often guided by cell protrusions, whose formation and activity involve subcellular local
115 esents a multilayered biomolecular condensate, whose formation by liquid-liquid phase separation (LLP
116 s responsible for de novo purine biosynthesis, whose formation has been associated with elevated puri
119 pre-senescent cells was G:C->T:A transversion, whose frequency was intensified in the treated immorta
120 limacteric fruit with elevated phytonutrients, whose fruit quality attributes are prone to rapid dete
125 o both c-KIT and to the RasGAP, neurofibromin, whose function is completely dependent on this interac
127 ation which leads to the (pro)amniotic cavity, whose function is to distance the central epiblast fro
131 replication and coopt numerous host proteins, whose functions during virus replication are not yet c
133 dentified cell surface markers, CD69 and CD36, whose genes were differentially expressed between thes
134 erential GRNs in cancer versus normal tissues, whose genes with largest network degrees have been rep
135 s a rare type of sex cord-stromal tumor (SCST), whose genetic underpinning is currently unknown.
136 elevance to the crystal engineering community, whose goal is the design of solids with bespoke proper
137 then propose a reverse translational approach, whose goal is to develop models that mimic successful
138 free and open access web server, AWSEM-Suite, whose goal is to predict monomeric protein tertiary st
139 bs presage the site of the manubrium blastema, whose growth is Wnt/beta-catenin dependent and fueled
141 treatment options for FGFR4-positive patients, whose high expression is not caused by mutation or amp
142 sure prophylaxis (PrEP) for transgender women, whose HIV prevalence estimates are as high as 25% in s
145 They contain poly-histidine chains (poly-His), whose imidazole groups generate (14) N-quadrupolar-pe
147 ybrid PKS module harboring KR1 was engineered, whose individual catalytic domains have been crystallo
149 ted by a cGMP-dependent protein kinase (PfPKG), whose inhibition is a promising antimalaria strategy.
151 omplexes (nodes) of RNA-binding domains (RBDs), whose integrated RNA-binding capacity determines whet
152 is reflected by the formation of compartments, whose interactions form a characteristic checkerboard
153 tors involved in resolution and tissue repair, whose intracellular signaling remains of interest.
154 We identified several drosophila CYPs (dCYPs) whose knockdown reduced PCB 28-derived OH-metabolites
156 covalent organic frameworks, called COFamides, whose layers are held together by amide hydrogen bonds
157 contains a disordered C-terminal domain (CTD) whose length enigmatically correlates with genome size
158 ops around a thin (<130 nm) MukBEF axial core, whose length is ~1,100 times shorter than the chromoso
159 ely in KPC/Cdh11(+/-) and KPC/Cdh11(-/-) mice, whose lesions also contained fewer FOXP3(+) cells in t
160 eloped for the two-phase synthesis of taxanes, whose lessons can be potentially extrapolated to medic
162 S antibodies are produced by atypical B cells, whose levels correlate with the development of anemia
163 totypic endocytic receptor of dendritic cells, whose ligands include phosphorothioated cytosine-guano
164 creen printing, and electron-beam lithography, whose limitations have hampered rapid innovations and
165 ameter comes in the form of a range of values, whose limits are delta(RA)/(12)(1/2) and delta(RA)/(3)
166 probability with active neighbors in layer 2 (whose links can be thought as potential casual partner
167 e bilayer organizes in multiple lipid domains, whose location is pinned in specific regions, dependin
169 more, we identified a phosphodiesterase, PdeV, whose loss promotes biofilm formation similar to that
170 trinuclear u(3)-oxo-bridged Mn(III)-based SMM, whose magnetic anisotropy is closely related to the Ja
171 mitochondrial component of folate metabolism, whose malfunction results in accumulation of glycine a
172 e involved with the tryptophan/indole pathway, whose malfunctioning has been linked to pathologies in
173 mining and the International Seabed Authority, whose mandates include regulation of all mineral-relat
174 scribe here probably the first molecule (RBM3) whose manipulation affects translation specifically in
175 uiding selective self-assembly using silver(I), whose many stable coordination geometries render desi
176 re tested psychophysically in human observers, whose measured differences in the diameters of each en
177 actor in diffuse large B-cell lymphoma (DLBCL) whose measurement requires the segmentation of all mal
179 4E-binding site and three other phospho-sites, whose mechanisms in inhibiting binding are not underst
180 IM protein families (zyxin, paxillin, and FHL) whose members preferentially localize to the actin cyt
181 ed protein from the tortricid family of moths, whose members cause billions of dollars in losses to a
182 ion of llamas, a member of the camelid family, whose members generate conventional heavy/light-chain
183 ticularly troublesome when evaluating grasses, whose members represent our most agriculturally signif
184 ~38,000 idle wells, and ~63,000 active wells, whose methane (CH(4)) emissions remain largely unquant
185 for the homeostasis of airway surface liquid, whose misregulation is associated with respiratory con
186 (at 540 degrees C) to nitrogen dioxide (NO(2)), whose mixing ratio is monitored via its absorption a
187 din are promising leads in AD and PD research, whose mode of action has not been fully established ye
189 ion modelling, we predict targetable pathways, whose modulation repairs mitochondrial dysfunctions in
190 on clinics at the primary health-care centres, whose mothers gave consent, were tested by the HemoTyp
192 a novel biomarker, coenzyme A synthase (COASY), whose mRNA expression was consistently elevated in ra
193 HGT is the holoparasite Lophophytum mirabile, whose mtDNA has lost most native genes but contains in
194 Here, we show that the prd-2 (period-2) gene, whose mutation is characterized by recessive inheritan
196 ere we report that transcription factor GATA6, whose mutations in humans are linked to arrhythmia, is
197 agination of the outer mitochondrial membrane, whose necked aperture to the cytoplasm is gated by a 1
198 gene, CONSTANS, CO-like, and TOC1 101 (CCT101), whose nitrogen-responsive isoform-specific RNA expres
199 leaves behind a mosaic of monoallelic patches, whose number and size are highly sensitive to the dist
200 ls in both regions were identified as neurons, whose numbers remained stable over time, suggesting th
201 population of ITGA6(+)ITGB4(+) mitotic cells, whose offspring further segregated into a TNFRSF12A(hi
202 the case of the amyloid beta (Abeta) peptide, whose oligomers are associated with Alzheimer's diseas
204 polystyrene sulfonate (PEDOT:PSS) thin films, whose optical absorption can be modulated by an applie
205 t, we focus on mechanosensory bristle neurons, whose optogenetic activation induces a similar sequenc
207 ytes is defined by kinesin-myosin competition, whose outcome is primarily determined by cortical micr
208 ic helix-loop-helix transcription factor (MYC), whose overexpression is commonly associated with aggr
209 yt1 binds putative enhancers of Atf4 and Hsps, whose overexpression largely recapitulated the Myt-mut
210 re modes (basic food, other food and non-food), whose parameters are probabilistically estimated usin
211 the Framingham Heart Study, offspring (n=235) whose parent(s) had a sex- and age-standardized aortic
212 during rheumatoid arthritis and osteoporosis, whose pathogenesis is associated with a Th17/Treg imba
213 ctive layer of bulk heterojunction solar cell, whose performance is strongly correlated to the struct
214 ned fixation, were used to train a classifier, whose performance was then tested on saccade trials.
215 optic based label-free biosensor is presented, whose performance were verified through the detection
216 nefitted White men who have sex with men (MSM), whose population has increased over the past decade.
219 al mutations that affect non-hotspot residues, whose potential functional contributions to disease ar
220 ally diverse metabolites in biological system, whose potentials for chemical expansion, however, have
221 DNA) genome with 31 open reading frames (ORFs), whose predicted gene products show little homology to
224 ropean Union Emissions Trading System (EU ETS), whose price remained low (compared to the social cost
226 n 1,002 coronary heart disease (CHD) patients, whose primary objective is to compare the effect of 2
227 this problem in the Drosophila mushroom body, whose principal neurons, Kenyon cells, receive feedbac
228 actic GPCR-7TM formyl peptide receptor family, whose principle function is in trafficking of various
229 n the gene encoding amyloid precursor protein, whose processing can result in formation of beta-amylo
230 inding is then performed by the PcrA helicase, whose processivity is critically promoted by its inter
231 the folylpolyglutamate synthetase (FPGS) gene, whose product catalyzes the addition of multiple gluta
232 , and Herpud2 as the most probable candidates, whose product dysfunction might be responsible for the
233 complex bound to the promoter region of Nanog, whose product regulates genes that control stemness.
234 ction of capsid proteins and other late genes, whose production is transcriptionally controlled by a
235 nature of the insulating ground state of VO(2), whose properties have been an issue for accurate pred
236 hift 0.0337 +/- 0.0002) massive spiral galaxy, whose properties and proximity distinguish it from all
239 tations in the presenilin 1/2 (PSEN1/2) genes, whose protein products partially compose the gamma-sec
240 able but still highly stable in aqueous media, whose proteolytic degradation could be used in these w
241 Electrophysiological studies of W1282X-CFTR, whose PTC is closer to the C-terminus of CFTR, suggest
243 ion profile: the long noncoding RNA ephemeron, whose rapid upregulation is crucial for the transition
244 ion using distyrylbenzene-bis-aldehyde (DSB-3), whose reaction with PE produces a fluorescence signal
245 ytic cleavage of the RNA model substrate HPNP, whose reactivity is 30-fold larger with respect to the
246 the leading examples of interlocked molecules, whose recent developments in synthetic chemistry have
247 eracting with the heat shock protein, Hsc70-4, whose reduction diminishes ataxin-3 toxicity in a UIM-
248 n association between an i-modulon and sigmaS, whose regulatory role was previously undefined; 3) the
249 are polar and/or ionizable organic compounds, whose removal from engineered and environmental system
251 y TRIB3 as a key component of the spliceosome, whose repression contributes significantly to the mech
252 exists in mice, humans secrete IgA1 and IgA2, whose respective relations with the microbiota remain
254 has not been observed in the piriform cortex, whose responses to odorants are sparsely distributed a
255 rt a laser rewritable magnetic composite film, whose responsive shape-morphing behaviors induced by a
256 andom forest classifier to develop the system, whose results were compared to the clinical grading of
257 y extending the study to non-Newtonian fluids, whose rheological profile is approximated by the Carre
258 this goal is the connectivity of the network, whose role in altering gene expression remains unclear
259 of self-assembled molecular-electronic films, whose room-temperature transport properties are contro
260 rtially colocalized with nuclear paraspeckles, whose scaffolding lncRNA NEAT1 is dramatically upregul
261 Transcription of F3 was regulated by IL1beta, whose secretion decreased upon inhibition of GSTO1, su
263 lly structured loop in the glutaminase domain, whose sequence is present in eukaryotic enzymes but ab
264 (+) concentrations (6 to 150 mM), unlike KcsA, whose SF collapses at low permeant ion concentrations.
265 NC, tuning-compatible noise correlation (TCNC), whose sign and magnitude are systematically related t
266 urafenib causes feedback upregulation of EGFR, whose signaling activities can be impeded by cetuximab
267 ming growth factor beta (TGF-beta) expression, whose signaling pathway synergizes with the EGFR casca
268 ly of DNA polymerases (POLA1, POLE, and POLE2) whose silencing sensitized the human A549 non-small ce
270 ically encoded multimeric nanoparticles (GEMs), whose sizes are commensurate with the inter-filament
271 an "stony" corals are major habitat engineers, whose skeletons form the framework for the highly dive
272 ture elements in a protein are known as loops, whose slight change will produce dramatic effect on th
273 ive hippocampal place cells with large fields, whose spatial representations are refined by sensory e
275 ained via carefully crafted flexible elements, whose specific geometry and local dynamics are designe
276 dered MuPyV resistant to a monoclonal Ab (mAb), whose specificity overlapped the endogenous anti-VP1
277 n CLCN6 associated with neurological diseases, whose spectrum of clinical features depends on the dif
279 rate a large amount of hypersaline wastewater, whose spills or discharges may significantly increase
281 rticles with tunable dimensions and curvature, whose structure and dynamics are accessible at the par
282 cheme to Pb(4)S(3)I(2) colloidal nanocrystals, whose structure matches the one that has been publishe
283 quenced genomes and to discover 3 novel RiPPs, whose structures are exactly as predicted by our platf
284 via long-lived partially folded intermediates, whose structures, potentially toxic oligomerization, a
286 ) and cadherin-23 (CDH23), form the tip-links, whose tension gates the hair cell mechanoelectrical tr
288 coli chaperone holdase family, RidA and CnoX, whose thiol-independent activation mechanism differs f
289 vanced intermediate as the key building block, whose three-step conversion to the natural product all
290 used in laboratory routine is the antibiogram, whose time to obtain the results can vary from 1 to 3
292 uch as Angpt1, Tgfb2, Tgfb3, Itga8, and Itgb7, whose transcription is regulated by Ambra1-scaffolded
293 s 2-AG-mediated activation of CB(2) receptors, whose transcription may be induced by the stress itsel
295 east abundant amino acid residues in proteins, whose unique chemical and physical properties often cr
296 ptotic member of the Bcl-2 family of proteins, whose upregulation in human cancers is associated with
297 FE are mainly produced by micro-organisms, whose viable strains nor associated DNA can be present
298 e-, sex-, and BMI-matched patients, all obese, whose visceral E2F1 protein expression was either high
299 is a weighted network, the gene proximity map, whose weights are based on the contact frequencies bet
300 ase assembly integral membrane protein (VMA21), whose X-linked mutations lead to autophagic myopathy.