ライフサイエンスコーパス: -based

1 Among these, Sm(2) Co(17) -based magnets are excellent candidates owing to their hi

2 s the catalogue of qubit materials to Ni(2+)-based compounds and offers a future pathway for optical

3 We recently used CRISPRi/a-based chemical-genetic screens and cell biological, bioc

4 hnology has opened a new era of nucleic acid-based molecular diagnostics.

5 ve found widespread applications as activity-based probes and as irreversibly binding drugs.

6 for the synthesis of two ubiquitin activity-based probes (Ub-ABPs) employing solid phase chemical li

7 the applicability of an untargeted, activity-based approach for SCRA detection in OF.

8 the effects of varied representations of AI-based support across different levels of clinical expert

9 oselective acyl transfer promoted by amidine-based catalysts (ABCs) and a racemic chain mechanism med

10 The key challenge in generating antibody-based inhibitors is the lack of fundamental information

11 Bevacizumab was chosen as the antibody-based therapeutic.

12 Unlike the traditional antibody-based immunoassays, our approach is capable of monitorin

13 ion to host processes, we develop an aqueous-based encapsulation formulation with a microbiota-based

14 me Atlas (TCGA), with both RNA-Seq and array-based platforms available.

15 Bead-based epitope assay (BBEA) was used to quantitate the le

16 s developed a fully automated multiplex bead-based assay for the detection of IgM and IgG antibodies

17 nity assembly mechanisms by phylogenetic bin-based null model analysis (iCAMP).

18 ter signal-to-noise ratio, a bioluminescence-based assay was developed against IFN-gamma and provided

19 n overview of the literature on carbon black-based electrochemical (bio)sensors, highlighting current

20 ial focus on the fabrication of carbon black-based electrodes in the realisation of sensors and biose

21 oron cluster cage and an exopolyhedral boron-based substituent (e.g., -BF(3)K, -B(OH)(2)).

22 We performed behavioral and brain-based experiments, with the latter employing electroence

23 e results provide novel behavioral and brain-based targets for treatment of pediatric anxiety disorde

24 r these classes of anionic mesoionic carbene-based ligands.

25 has attracted attention for realizing carbon-based electronic devices.

26 However, current CRISPR-Cas-based nucleic acid biosensing has a lack of the quantita

27 a library of 645,000 compounds using a cell-based calcium detection system.

28 ults that could provide new options for cell-based therapeutics with curative intent.

29 aying the framework for optimization in cell-based therapeutics intended to mitigate cardiomyopathic

30 In live cell-based assays, LGI1 epitope recognition was examined with

31 rapy and has general implications for T cell-based immunotherapies.

32 iently inhibiting LDH during adoptive T cell-based immunotherapy, with an unanticipated cooperative a

33 not receive guideline-directed cephalosporin-based prophylaxis, which may result in an increased SSI

34 is regulated in the European Union in cereal-based foods for infants and young children, tea and herb

35 Owing to its chelate-based construction, Fe-HAF-1 displays exceptional chemic

36 A click chemistry-based flux assay reveals that necrocytosis provides not

37 Here we identify an adaptive circuit-based mechanism that enables Drosophila to form sleep-de

38 say performance was evaluated in four clinic-based prospective cohorts.

39 group was moderate for multicomponent clinic-based interventions but was low or very low for other in

40 eased viral suppression compared with clinic-based ART, particularly among men, eliminating dispariti

41 he existence of an underlying adaptive codon-based regulatory response inherent to the genetic code.

42 roteomic methods to rely solely on collision-based fragmentation rather than electron-driven dissocia

43 n asylum seeker populations (i.e., community-based arrangements, community detention, onshore immigra

44 However, few community-based studies have been published and the true PeV infec

45 Using data from a large, community-based integrated health care setting, we examined the ri

46 ttings in South Africa and Uganda, community-based delivery of ART significantly increased viral supp

47 First, NZ's production- and consumption-based emissions were quantified using multiregional inpu

48 idified solutions for the extraction of corn-based anthocyanins.

49 the development of new fluorescent coumarin-based probes by researchers in the field.

50 Here, we developed a CRISPR-based system for simultaneous quantification of mRNA and

51 Here, we develop a dCas9/CRISPR-based system that allows ectopic targeting of Ctf19c-sub

52 pe.Objectives: To determine whether such Crs-based phenotypes existed among patients with ARDS before

53 st response assessment with both PET- and CT-based criteria.

54 and the results of the gold-standard culture-based AST measured over days.

55 In this work, two new curvature-based angularity indices are introduced and compared to

56 Dried blood spots (DBS)-based drug resistance testing, widely studied for HIV-1,

57 enabled glaucoma dashboard." We used density-based clustering and the VF decomposition method called

58 In summary, our yeast-display-based platform yields high-quality MHC-II-binding peptid

59 Herein, we rationally design a DNA-based artificial molecular signaling system that uses th

60 sors (e.g. enzymatic, immunosensors, and DNA-based).

61 rculation by both mRNA-based and genomic DNA-based sequencing.

62 eat potential to improve the efficacy of DSF-based cancer therapy.

63 switch to WHO-recommended dolutegravir (DTG)-based regimens could reduce this threat due to DTG's hig

64 arios if ART initiators are started on a DTG-based regimen, and those on NNRTI-based regimens are rap

65 % [214/248], P = 0.002) and for those on DTG-based treatment (61/92 [66%] vs 84% [391/465] P < 0.001,

66 When given to all men and women, DTG-based ART could reduce the level of NNRTI PDR from 52.4%

67 [605/713], P < 0.001), and for those on EFV-based treatment (60% [12/20] vs 86% [214/248], P = 0.002

68 The EHR-based case-control studies identified that the prescript

69 Using paired collision- and electron-based dissociation spectra, O-Pair Search identifies O-g

70 le enzyme-linked immunosorbent assay (ELISA)-based assay that uses the temperature-dependent loss of

71 This indicates that linear, equilibrium-based model assumptions may fail at predicting populatio

72 ogether, these data provide physiological EV-based insights into the mechanisms of human malaria path

73 Evidence-based guideline development for surgical and dental pres

74 Evidence-based interventions can deliver substantial public healt

75 discuss the contemporary role of an evidence-based fibrinolytic reperfusion strategy as part of a pha

76 Utilizing an evidence-based framework, 3 gene curation teams blinded to each o

77 ibe research pipelines that broaden evidence-based approaches and the pathobiology of these novel eve

78 nexpected based on efficacy data or evidence-based guidelines.

79 This evidence-based intervention could be part of EtHE.

80 replace traditional lecturing with evidence-based, active-learning course designs across the STEM di

81 Our study reveals that ad hoc or experience-based flow management is no longer tenable to maintain t

82 uracy, we performed a large number of expert-based annotations, 72,722 in total.

83 learning approach, we built gene expression-based models to predict drug sensitivity for 265 common

84 d to the improved downstream gene expression-based prediction of disease outcome.

85 procedures versus 50% to 97.7% for facility-based procedures.

86 action detection system as well as novel FAP-based sensors.

87 r than most of the reported Ni-, Co-, and Fe-based bifunctional electrocatalysts.

88 All single feature-based LightGBM models were then integrated into a unifie

89 Field-based brain imaging research, including populations unde

90 This filament-based mechanism of enhanced cooperativity demonstrates h

91 f MTCH2 using luminescence- and fluorescence-based assays, and by analyzing ribosome-profiling and ma

92 Thus, our FRET-based nanoparticle biosensor enables detection of nuclei

93 These fusion-based estimates can be a valuable resource when assessin

94 llege of Radiology as a group III gadolinium-based contrast agent (GBCA), which indicates that there

95 aging after interstitial pedal of gadolinium-based contrast medium under local anesthesia.

96 safe and improved alternative to gadolinium-based chelates.

97 gates and a comprehensive set of ganglioside-based glycoconjugates.

98 Detection of animal materials in gelatin-based products is required to address religious and cult

99 nd that patients who progress on gemcitabine-based regimens may benefit from multidrug immunotherapy.

100 Gene-based rare variant tests implicated a known prostate can

101 The system consists of GFP-based reporters that become fluorescent upon cleavage by

102 covalent attachment of a synthetic glutamate-based photoswitch via a self-labelling SNAP tag.

103 indicates that pre-harvest use of glyphosate-based herbicides can cause significant differences in wh

104 use for biomedicine, only a few of the gold-based nanodevices are currently tested in clinical trial

105 We developed a gradient-based unsupervised clustering method to extract the patt

106 We present SVXplorer, which uses a graph-based clustering approach streamlined by the integration

107 s were treated with gemcitabine and S-1 (GS)-based chemotherapies with/without radiation.

108 adaptive signature was detected in haplotype-based analysis but not in polygenic score-based analysis

109 Simulation result indicates that HD-based selection algorithm is effective in recognizing ke

110 's) and 20 age-matched controls, using a HOA-based through-focus analysis performed on the logNS IQ m

111 ice, 11.9% in rural location, 26.8% hospital-based, and 24.6% in primary care).

112 We also examined hospital-based affiliation.

113 dated objective and individual-level housing-based SES index (HOUSES) would serve as a predictive too

114 al treatment, along with other emerging HRP2-based applications, including detection of submicroscopi

115 proposing a new model that has a hydraulics-based penalty function that meets all seven criteria and

116 f TE insertions that were missed by Illumina-based methods, including a novel micropia-like element t

117 cability of our approach to facilitate image-based pooled CRISPR screens.

118 recent achievements in the accuracy of image-based AI for skin cancer diagnosis to address the effect

119 ion deficient cellular phenotypes, the image-based algorithm was studied prospectively on 10,240 CTCs

120 y slowly progressive, and objective, imaging-based biomarkers are critically needed.

121 with liver injury is indicative of an immune-based mechanism for the observed hepatic enzyme elevatio

122 l hundred clinical trials have tested immune-based approaches in childhood cancers, few have been gui

123 onclusion, the results support an individual-based definition of health and show that comprehensive o

124 ough a unique mechanism of anti-inflammation-based fibrotic scar reduction.

125 To inform the development of insect-based foods, we analysed selected minerals (Fe-Mn-Zn-Cu-

126 inefficiencies of the U.S. private insurance-based, multipayer system.

127 Integrin-based focal adhesion complexes link the glial membrane t

128 Artificial intelligence-based detection achieved a higher level of accuracy.

129 A specific class of deep learning-based methods allows for the prediction of regulatory ef

130 The efficient ligand-based design approach adopted demonstrates its versatili

131 development of biomaterials suited for light-based 3D printing modalities with an emphasis on bioprin

132 g opportunities for the future of macrophage-based therapies in oncology are included.

133 I), the United States' first regional market-based regulatory program designed to reduce greenhouse g

134 article properties and compared them to mass-based exposures.

135 mmittee machines-in the context of memristor-based neural networks.

136 erforms maximum likelihood analyses, a k-mer-based set difference algorithm, and random forest algori

137 be used for the growth of other noble-metal-based delafossites, which are known to be challenging du

138 ransport capabilities using metalloporphyrin-based supramolecular arrays.

139 ased cardiovascular risk receiving metformin-based background therapy, specific GLP-1 RAs and SGLT-2

140 The tool guided an MI-based conversation between coach and patient to identify

141 he immunotherapeutic efficacy of a microbial-based stimulus for innate immune mobilization depends on

142 encapsulation formulation with a microbiota-based release mechanism and show that it facilitates ora

143 ovide insights into the future of microbiota-based therapeutics for CDI.

144 nfrared and highlight an electron-microscopy-based approach for probing complex-shaped nanophotonic s

145 Finally, microscopy-based metabolic analysis revealed that migratory cells s

146 phogenesis of the rhabdomere, the microvilli-based photosensitive organelle of Drosophila photorecept

147 IN, a web server that couples a graph mining-based strategy to detect motifs at the protein-ligand in

148 analysis and development of improved mixture-based, high-throughput drug discovery techniques.

149 Model-based decisions use predictions of the specific conseque

150 ssary to develop robust, reliable, and model-based experimental probes; recruit larger sample sizes;

151 d iterative reconstruction (SBIR), and model-based iterative reconstruction (MBIR) in a retrospective

152 e a quantitative baseline to constrain model-based hypotheses of plant responses to eCO(2) under P li

153 reveal that ACC is a critical node in model-based control, with a specific role in predicting future

154 of rewarded actions, and the other is model-based learning, which considers the structure of the env

155 Data-driven modularity-based parcellation of the rat medial prefrontal cortex (

156 forms any previously reported values for MOF-based systems.

157 which directly provides the direct molecular-based design of functionalized polymer/carbon spheres.

158 ration (DBA) be used as a proxy for movement-based power.

159 scheduled multiple-reaction monitoring (MRM)-based targeted proteomic approach to quantify systemical

160 ere detected in the circulation by both mRNA-based and genomic DNA-based sequencing.

161 ospray ionization mass spectrometry (ESI-MS)-based sample injection at a sampling rate faster than cu

162 this technology with mass spectrometry (MS)-based proteomics allows us to obtain snapshots of molecu

163 Our ICP-MS-based method comprises the analysis of 20 elements (Mg,

164 the safety and efficacy of an allogenic MSC-based intramammary therapy in dairy cows with experiment

165 emonstrate that the capacity for rapid Na(+)-based signaling in eukaryotes is not restricted to anima

166 s, utilizing a recently established NanoBRET-based ligand binding assay.

167 a robust and smart "all-in-one" nanoparticle-based drug delivery system capable of overcoming biologi

168 We applied nanopore-based direct RNA sequencing to characterize the developm

169 Moreover, nanoscaffold-based approaches promote significant axonal growth and f

170 ronic toxicity evaluations of nanotechnology-based drugs are essential to support initiation of clini

171 the tick-host relationships using a network-based construct.

172 transcriptome profiling and applied network-based and probabilistic causal methods to identify sever

173 and has significant implications for network-based interventions.

174 We develop an Individualized Network-based Co-Mutation (INCM) methodology by inspecting over

175 ameters through convolutional neural network-based image processing, including relative area under th

176 e catalytic systems (two Pd-based and one Ni-based) for the direct borylation of aryl (pseudo)halides

177 NMR-based molecular-level characterization identified the do

178 atic activity of p97 in real time via an NMR-based approach that allows us to follow the steps that c

179 that, compared to the continuation of NNRTI-based ART, introducing DTG would lead to a reduction in

180 d on a DTG-based regimen, and those on NNRTI-based regimens are rapidly switched to DTG.

181 opment of a tantalum oxide nanoparticle (NP)-based mass tag for MC immunoassays.

182 emical properties relative to the original O-based analogue.

183 surgery ranged from 66% to 95.6% for office-based procedures versus 50% to 97.7% for facility-based

184 e, we provide an overview of oligonucleotide-based drug platforms, focusing on key approaches - inclu

185 me 10 in the materials using oligonucleotide-based haplotype-specific chromosome painting.

186 Fiber-optics-based cuvetteless micro-spectrophotometry has been used

187 resent a simple tool, extensible to Orbitrap-based mass spectrometers, for postdetection data process

188 Organ-based correlations of alkaloid content, OMT activity in

189 of 3 new adipose IR genes by overexpression-based phenotypic rescue in the Simpson-Golabi-Behmel syn

190 oratories simply connected by regular, paper-based mail.

191 The paper-based sensor was then engineered with a novel and highly

192 vironmental conditions and emerging pathogen-based diseases.

193 research teams and their application in PCR-based diagnostics, high-affinity DNA aptamer generation,

194 eaction pathways using bases and a simple Pd-based catalyst system to promote a para-selective C-H fu

195 plication of three catalytic systems (two Pd-based and one Ni-based) for the direct borylation of ary

196 try, for the fabrication of a Bio-Nano-PEDOT-based biosensor for lactate detection which had a respon

197 mily of 3-19 nM-affinity, alpha/beta-peptide-based binders to 14-3-3.

198 diment for the design of sustainable peptide-based antibiotics that can be hydrolyzed by wastewater p

199 In many cases, these peptide-based catalysts have enabled novel multifunctional subst

200 (PEM) fuel cell, platinum-group-metal (PGM)-based catalysts account for ~50% of the projected total

201 Choline chloride:phenol-based DES showed the best results.

202 al neuromodulation using low-frequency piezo-based transducers offers poor spatial confinement of exc

203 Wines fined with egg albumin and plant-based proteins from potato, pea, and grape seed as recen

204 s, relying on a mix of animal prey and plant-based resources.

205 n technique, was used to fortify three plant-based food models: carbohydrates/acidic pH/sweet - beetr

206 ephthalate) substrates to which polyacrylate-based sensing and polymethacrylate-based reference membr

207 ress this question, we developed a polymeric-based constructed graft system (CGS) as a physiologicall

208 ibe an ultrasensitive form of polymerization-based regulation employed by human CTP synthase 2 (CTPS2

209 yacrylate-based sensing and polymethacrylate-based reference membranes are attached covalently.

210 Anion transport experiments in POPC-based large unilamellar vesicles show that these main-gr

211 ting in the Generation R Study, a population-based birth cohort in Rotterdam, Netherlands (enrollment

212 In a population-based study (Oxford Vascular Study/2002-2018) of patient

213 In a population-based study in Iceland, children under 10 years of age a

214 In this large, population-based, family database, the risk of PC varied by cancer

215 We conducted a multicountry population-based cohort study of all recorded singleton live births

216 ubles the estimated efficiency of population-based newborn screening to prevent ketoacidosis, and ena

217 perforation in the context of the population-based Surveillance of Enteric Fever in Asia Project (SEA

218 This population-based retrospective cohort study assessed whether a vali

219 5 in Sweden were enrolled in this population-based, nationwide, and prospective cohort study.

220 Here, we use population-based data from ~22,000 persons of known HIV status to c

221 Here, we apply a high-resolution, pressure-based approach to describe how two fishes, bluegill sunf

222 lycosites using graph theory and probability-based localization.

223 of transient, nanoscopic lipid- and protein-based interactions confer a steady-state organization of

224 al delivery and storage stability of protein-based vaccines.

225 vaccine 4CMenB is a new, recombinant protein-based vaccine that is licensed to protect against invasi

226 The production of soy protein-based foods requires multiple-step, intensive processing

227 Patients underwent prospective, protocol-based monitoring consisting of repeated coronary angiogr

228 Rate-based calculations in packing column demonstrated a kine

229 promising approach for constructing reaction-based chemosensors using porphyrinoid dimers of nonplana

230 ISPR-array-mediated primer-exchange-reaction-based biochemical circuit cascade, which probes a specif

231 , used routinely acquired data for a records-based controlled before-and-after study, and collected q

232 oposed, to achieve harmonization of registry-based quality outcome measures for TEVAR.

233 red to as the testing effect or as retrieval-based learning) and consider directions for future resea

234 ggregate patients within RCTs to define risk-based variation in benefit, and an "effect-modeling" app

235 In this review, we focus on noncoding RNA-based studies conducted mainly in large-animal models, i

236 dietary fiber intake using 16S ribosomal RNA-based approaches.

237 Using ROI-based fMRI analysis, we measured fMRI activity for valid

238 ds can significantly activate single-site Ru-based catalysts.

239 Rule-based models are particularly well-suited to this approa

240 ollowed by linkage disequilibrium (LD) score-based enrichment testing for each trait.

241 pe-based analysis but not in polygenic score-based analysis.

242 prefrontal cortex (mPFC) combined with seed-based connectivity analysis with the striatum recapitula

243 alidated internal mRNA m7G sites, a sequence-based high-accuracy predictor, the first web server for

244 ted chromatin immunoprecipitation-sequencing-based analyses demonstrate that direct readout of H3K27m

245 the surface-enhanced Raman scattering (SERS)-based molecular sensors for detection of two putative fa

246 ed 10 studies of the use of autologous serum-based eye drops for severe dry eye disease and 4 studies

247 The use of test set-based assessment schemes in a breast screening program h

248 y kinetic simulations of laser driven sheath-based ion acceleration with a kilotesla-level applied ma

249 ogeneities on the structural stability of Si-based lithium-ion batteries.

250 est in using macrocyclic cores for in silico-based lead generation and also inspire the design of fut

251 sors with extremely well-established silicon-based microcircuit chips offers a viable route for in-se

252 Climate simulation-based scenarios are routinely used to characterize a ran

253 In this article, we utilized a smartphone-based image acquisition method for capturing RBC images

254 three-dimensional cartridge and a smartphone-based reader.

255 ic spacer for the fabrication of mixed Pb/Sn-based perovskites, exhibiting a narrow bandgap of 1.27 e

256 lso opens the door for nanoengineered, solar-based methods to remediate recalcitrant micropollutants

257 d for the design of tandem mass spectrometry-based CAD sequencing strategies for mixtures of lignin d

258 length gB protein with an MF59-like squalene-based adjuvant, the gB ectodomain protein (lacking AD-3)

259 filtered back projection (FBP), statistical-based iterative reconstruction (SBIR), and model-based i

260 Structure-based bioinformatic analysis identified 10 subfamilies o

261 Computationally efficient all-atom structure-based simulations, calibrated against explicit solvent s

262 ding practices and promoted use of structure-based feeding among first-time parents compared with con

263 al inhibitors was achieved through structure-based inhibitor design.

264 Sulfur-based ligands are versatile donors that play important r

265 Cell surface-based loss-of-function screens reveal that ATP7A, a copp

266 Given that symptom-based classification approaches do not align with underl

267 Combining a series of synchrotron-based techniques with Raman spectroscopy and scanning el

268 evance with a post hoc meta-analysis on task-based fMRI.

269 We have also developed a temperature-based screening method for synthetic paralysis that can

270 A series of tetrahydroisoquinoline-based benzodiazepine dimers were synthesized and tested

271 h(6) secondary building unit and a tetrazole-based linker.

272 ially inhibited by sulfonamide and tetrazole-based derivatives, NDM-1 by compounds bearing a thiol, a

273 indings reveal an unexpected aspect of theta-based hippocampal encoding and provide a biological mech

274 For TIRS, the best strategy was threshold-based, which led to the fewest infections of all strateg

275 including metal organic framework design, TM-based catalyst design, the trafficking of TM ions in bio

276 (P = 0.003), and greater computed tomography-based emphysema (P = 0.02) compared with 1,411 white ind

277 no reaction is examined within a topological-based bonding evolution theory perspective.

278 ice of either sex either by diphtheria toxin-based ablation of >50% of mature DG granule cells (GCs)

279 and performed voxelwise analysis with tract-based spatial statistics.

280 Using a trait-based approach that incorporated genomic and phenotypic

281 tant complementary role to phylogenetic tree-based analysis, such as is done in the Nextstrain projec

282 olvement of PKCdelta in stimulation of TRPC1-based SOCs and highlight that store-operated PKCdelta ac

283 er, more resolved, and better-evaluated TWiG-based hypothesis supports the grouping of dromaeosaurids

284 (TCO)-bearing antibody and a tetrazine (Tz)-based radioligand via the rapid and bioorthogonal invers

285 ility, and stability of three series of urea-based sEH inhibitors.

286 Urine-based hrHPV testing may be a promising approach to impro

287 using a comprehensive battery of nine value-based decision-making tasks which yield ten distinct mea

288 tem was validated with the study of vanadium-based catalysts during propane oxydehydrogenation (ODH).

289 unravels a new molecular system for vesicle-based axonal transport of proteins in male and female fl

290 anagement can maintain the fidelity of video-based diagnostics in the face of missing values and vari

291 Here, we use a machine-vision-based single-particle analysis (SPA) method to successfu

292 .IMPORTANCE Vesicular stomatitis virus (VSV)-based oncolytic viruses are promising agents against pan

293 bset of 77 906 participants with up to 5 web-based 24-hour-recall food frequency questionnaires (2009

294 ional barrier, we have created a dynamic web-based platform, NASQAR (Nucleic Acid SeQuence Analysis R

295 ated ecosystem services modeled with the web-based tool AguAAndes.

296 an independent, confidential, voluntary, web-based survey sent electronically to 1643 United States h

297 o mitigate acrylamide concentration in wheat-based products.

298 Moreover, it relies on the local/window-based information while lacking to consider useful prote

299 erstanding of ion transport behavior in wood-based structures enhances the capability to design high-

300 g of Pt nanoparticles (NPs) embedded in a Zr-based UiO-67 MOF was subject to steady-state and transie