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3 pecifically recruited one of the two poly(A)-binding proteins, PABP2, and one of the six cap-binding
5 at mite group 13 allergens of the fatty acid-binding protein (FABP) family are sensed by an evolution
6 eripheral membrane protein of the fatty acid-binding protein family that functions in the formation a
7 etic perturbation that cellular nucleic acid-binding protein (CNBP) and La-related protein 1 (LARP1),
8 ed to the human single-stranded nucleic acid-binding protein Pur-alpha, as a component of germ granul
12 sions involves flightless I (FliI), an actin-binding protein that contains a leucine-rich-repeat (LRR
14 Furthermore, we show that a related actin-binding protein, advillin which shares 75% homology with
15 tin monomers directly, formins use the actin-binding protein profilin to dynamically load actin monom
18 rk of actin filaments and associated F-actin-binding proteins, is fundamentally important in eukaryot
19 (shootin1) and show that, unlike known actin-binding proteins, SHTN1's actin binding activity is intr
20 es (VBSs) from different nonhomologous actin-binding proteins use conserved helical motifs to associa
21 n's interactions with myosin and other actin-binding proteins are essential for cellular viability in
23 s requiring the involvement of several actin-binding proteins, many of which are still unidentified.
25 ptor interacting protein 1 (GRIP1), an AMPAR-binding protein shown to regulate the trafficking and sy
28 ure of the DNA-binding domain of a model ASO-binding protein PC4, in complex with a full PS 2'-OMe DN
29 to collagens, such as Ltbp2 (latent TGF-beta-binding protein 2) and Sulf1 (sulfatase 1), which are tr
30 volution of chlorosis, describe a biliverdin-binding protein in vertebrates, and introduce a function
33 in 1beta (nsp1beta) and host protein poly(C)-binding protein (PCBP) 1 or 2 with the viral genome.
35 ogin (SCGN) is a recently discovered calcium-binding protein belonging to the group of EF-hand calciu
37 for calcium management (calmodulin, calcium-binding proteins), pH regulation (V-type proton ATPase),
40 density of structures expressing the calcium-binding proteins parvalbumin, calbindin, and calretinin.
42 Here, we found that the noncanonical 5' cap-binding protein eIF3d was activated in response to metab
43 sociated with loss of eIF4E, the mRNA 5' cap-binding protein of the initiation complex and binding pa
45 ing Complex (CBC), consisting of Nuclear Cap-Binding Protein 1 (NCBP1) and 2 (NCBP2), associates with
46 or subunit) and HIV-1 genes, and nuclear cap-binding protein 1 (NCBP1)/CBP80 is a component of HIV-1
49 tion that both KWL proteins are carbohydrate-binding proteins with distinct and likely tissue-related
50 ith an atypical chemokine receptor chemokine-binding protein 2 variant V41A (ACKR2-V41A; rs2228467).
52 Among the partially disordered chromatin-binding proteins, the H1 linker histone influences a myr
54 ed by the orchestrated function of chromatin-binding proteins that tightly control the expression of
55 arrangements, disorder within the chromatin-binding proteins facilitates promiscuous binding to a wi
57 t the promoter, recruits the C/EBPbeta (CREB-binding protein) and CBP transcription factors and activ
60 lical protein; and LUX ARRYTHMO (LUX), a DNA-binding protein required to recruit the evening complex
61 ns that associate with the chromatin and DNA-binding protein Barrier-to-autointegration factor (BAF).
63 the protein CHD8 [chromodomain-helicase-DNA-binding protein 8]) are among the most common mutations
64 s demonstrate that YaaA is a new type of DNA-binding protein associated with the oxidative stress res
66 on of mitochondrial single-stranded (ss) DNA-binding protein both influences the ways Twinkle loads o
67 LMO2 and LDB1 as well as single-stranded DNA-binding protein (SSBP) cofactors and DNA-binding basic h
68 -binding activity of the single-stranded DNA-binding protein RPA, efficient DNA replication through e
70 ges in the mitochondrial single-stranded DNA-binding protein, a crucial protein involved in mtDNA rep
71 pressing ALS-linked gene mutants for TAR DNA-binding protein (TDP-43) and superoxide dismutase 1 (SOD
72 ns of pathogenic deposits containing TAR DNA-binding protein 43 (TDP-43) are evident in the brain and
74 -synuclein in Parkinson disease, and TAR DNA-binding protein 43 in amyotrophic lateral sclerosis.
77 he nucleus, where it associates with the DNA-binding protein LAG-1/CSL to activate target gene transc
81 eosomes can influence, or be altered by, DNA-binding proteins, single-molecule techniques are increas
86 ur approach should be adaptable to other DNA-binding proteins as well as small proteins fused to DNA-
90 n proteins, we uncover a role for the dynein-binding protein LIS1 in promoting the formation of activ
92 SREBF1 encodes sterol regulatory element-binding protein 1 (SREBP1), which promotes the transcrip
93 oyltransferase 1a, sterol regulatory element-binding protein, acetyl coenzyme A carboxylase, and fatt
94 e transcription factor cAMP response element-binding protein (CREB) to enhance the expression of prot
95 found that loss of the cAMP response element-binding protein (CREB) transcription factor significantl
96 eramide-induced RIP of cAMP response element-binding protein 3-like 1 (CREB3L1) also involves RAT.
97 he epigenetic modifier cAMP-response element-binding protein-binding protein/p300 and thereby up-regu
98 ded on activation of cAMP-responsive element-binding protein (CREB) for induction of Ralpha2 expressi
99 s is maintained by sterol regulatory element-binding proteins (SREBPs), membrane-bound transcription
100 d by recruitment of the microtubule plus end-binding protein EB1/EBP-2 around the wound and actin rin
101 t decapentaplegic (SMAD)7 and CCAAT/enhancer-binding protein (C/EBP)delta, the transcriptional inhibi
102 the G allele interacted with CCAAT/enhancer-binding protein beta transcription factor (TF), while th
103 lls revealing upregulation of CCAAT/enhancer-binding protein homologous protein and immunoglobulin he
104 We observed that C/EBP-alpha (CCAAT/enhancer-binding protein-alpha) can act as a transcription factor
105 in stress marker insulin-like growth factor-binding protein 1 (IGFBP-1), were observed with 12-D(3)N
106 lloproteinase-2 x insulin-like growth factor-binding protein 7 and of renal resistive index to predic
107 oproteinase-2 and insulin-like growth factor-binding protein 7 was measured at H0, H6, H12, and H24.
108 lloproteinase-2 x insulin-like growth factor-binding protein 7 was poor with respectively an area und
109 lloproteinase-2 x insulin-like growth factor-binding protein 7 was unable to differentiate transient
110 alysis identified insulin-like growth factor-binding protein-5 (IGFBP-5) as a downstream target of JP
111 ollagen], IGFBP7 [insulin-like growth factor-binding protein-7], and GAL-3 [galectin-3]) were assesse
113 coli periplasmic glycerol-3-phosphate (G3P)-binding protein UgpB can serve, in the absence of its su
114 Together, our work revealed VEZF1 as a G4-binding protein, identified a novel regulatory mechanism
115 ensor and the transporter, utilize galactose-binding proteins that also bind glucose with the same af
118 Galectin-1 (Gal1), an endogenous glycan-binding protein, has emerged as a regulator of immune ce
121 an evolutionarily conserved family of glycan-binding proteins, have broad influence in tumor progress
122 erminants promoting glycan binding to glycan-binding proteins due to the ambiguity in microarray fluo
124 ta support a role for the predicted c-di-GMP-binding protein LapD in inhibiting LapG-dependent disper
126 e roles of the plant complement of small GTP-binding proteins in these cellular processes are describ
128 , which upregulates genes encoding guanylate-binding proteins (GBPs) and inducible nitric oxide synth
129 al antibodies (mAbs) raised against factor H-binding protein (fHbp) and Neisserial Heparin-Binding An
130 for HA-mediated motility, RHAMM, and the HA-binding protein TNF-stimulated gene 6 protein (TSG6).
132 cterized one of the newly-discovered heparin-binding proteins, C-type lectin 14a (CLEC14A), a member
134 adsorption system featuring immobilized P(i)-binding proteins (PBP) has recently attracted attention
138 macrophages, within the CSF express the iron-binding protein lipocalin-2 (LCN2) and its receptor SCL2
139 Here, we demonstrated that GULP1 was a KEAP1-binding protein that maintained actin cytoskeleton archi
140 r findings demonstrate that GULP1 is a KEAP1-binding protein that regulates KEAP1-NRF2 signaling in U
142 to C1q suggest an overlooked role as a lipid-binding protein, possibly generalizable to other C1q/TNF
143 ed that Fabp5, an abundant cytoplasmic lipid-binding protein found in brain endothelial cells, makes
144 D8, a Synaptotagmin-like Mitochondrial lipid-binding Proteins (SMP) domain-containing ER transmembran
147 t protein (MCP-1), autotaxin (ATX), and Mac2-binding protein (Mac2BP) were measured over 48 weeks.
148 ave shown that 5-HT(3A)-ICD fused to maltose-binding protein (MBP) directly interacts with RIC-3, wit
149 We found that DNA-binding and microtubule-binding proteins can diffuse on each other's substrates;
150 s, although both DNA-binding and microtubule-binding proteins can diffuse on the negatively charged b
151 ontrast, the lower net charge on microtubule-binding proteins enables them to diffuse more quickly th
152 entified signal-transducing adaptor molecule-binding protein (STAMBP) and ubiquitin-specific protease
153 target of Myb protein 1 (Stm1; SERPINE1 mRNA-binding protein 1 [SERBP1] in mammals), and recently, la
154 ribosome complexes are associated with mRNA-binding proteins, stress granule, and P-body proteins, w
155 ransport of cargo by motor proteins, many MT-binding proteins seem to adopt diffusional motility as a
157 a3 integrin and Galpha13 (guanine nucleotide-binding protein subunit alpha 13), resulting in the cons
158 g partners non-POU domain containing octamer-binding protein and splicing factor proline/glutamine-ri
160 iple pools is delivered to Sac1 by oxysterol-binding protein and related proteins in exchange for oth
161 by Osh1, a member of the conserved oxysterol-binding protein (OSBP) family of lipid transfer proteins
162 OSBPL1 encodes the full-length oxysterol-binding protein-related protein ORP1L, which transports
164 on of free PI(4)P via expression of a PI(4)P-binding protein in yeast strongly inhibited TBSV replica
165 the opposing functions of BRCA1 and the p53-binding protein 1 (53BP1)-associated complex in DNA rese
166 s of a beta-lactamase, PC1, and a penicillin-binding protein poorly acylated by beta-lactam antibioti
167 or peptidoglycan crosslinking by penicillin-binding protein 2 (PBP2) are unable to initiate polarize
168 ent peptidoglycan crosslinking by penicillin-binding protein 3 (PBP3/FtsI) initiate polarized divisio
169 single amino acid replacements in penicillin-binding protein 2X (PBP2X), a major target of beta-lacta
170 single amino acid substitution in penicillin-binding protein PBP2X that conferred a 2-fold increased
171 aluated pbp expression, levels of penicillin-binding protein (PBP) 5 (PBP5) and beta-lactam binding a
172 to bind to the allosteric site of penicillin-binding protein (PBP)2a, resulting in opening of the act
173 s conferred by mosaic variants of penicillin-binding protein 2 (PBP2) that have diminished capacity t
174 rands and crosslink them: class A penicillin-binding proteins (aPBPs) and complexes of SEDS proteins
175 role of the bifunctional class A penicillin-binding proteins (aPBPs) as well as the L,D-transpeptida
176 tidase (TP) activity catalyzed by penicillin-binding proteins (PBPs) separate into a pair of concentr
177 between adjacent wall peptides by penicillin-binding proteins to confer robustness and flexibility.
178 arget sites such as the ribosome, penicillin-binding proteins, and topoisomerases in a pharmacologica
179 actam pyrazolidinone that targets penicillin-binding proteins (PBPs) and incorporates a siderophore m
180 vel its details, we identified all phosphate-binding protein lineages in the Evolutionary Classificat
181 tent with adipogenesis, and the phospholipid-binding protein annexin A3 (AnxA3), a negative regulator
183 ludes conserved pyridoxal 5'-phosphate (PLP)-binding proteins that play a critical role in the homeos
185 crystallographically characterized porphyrin-binding protein that was programmed to not only bind a s
191 a(2) -Microglobulin (beta(2) -m) and retinol-binding protein 4 (RBP4) are normally reabsorbed with 'v
192 rotein (GFP), siderocalin (Scn), and retinol-binding protein 4 (RBP4) as model proteins and screened
193 ritin, soluble transferrin receptor, retinol-binding protein (RBP), 25-hydroxy vitamin D, folate, and
195 hly specific recognition of ribose by ribose-binding protein (RBP) to develop a single-protein ribose
198 ed that La-related protein 4 (LARP4), an RNA-binding protein (RBP) known to enhance mRNA stability, w
200 cytes expressed Lin28b, which encodes an RNA-binding protein associated with fetal hematopoietic gene
203 hogen Pseudomonas aeruginosa, RsmA is an RNA-binding protein that plays critical roles in the control
205 long 26 hr period phenotype, encodes an RNA-binding protein that stabilizes the ck-1a transcript, re
208 , RNA editing, nuclear pore composition, RNA-binding protein motif enrichment, and RNA secondary stru
209 related protein 6 (Larp6) is a conserved RNA-binding protein found across eukaryotes that has been su
212 could validate RBMS1, a barely described RNA-binding protein, as a new target gene for oncogenic miR-
215 suggesting a feedback between effective RNA-binding protein dosage and protein quality control in C9
217 arcoma (FUS) is a ubiquitously expressed RNA-binding protein implicated in familial ALS and frontotem
218 vity for the Drosophila Argonaute family RNA-binding protein AGO1, a component of the miRNA-dependent
219 excitement around ProQ as a novel global RNA-binding protein, and its potential to serve as a matchma
220 ngs demonstrate that FUS is an important RNA-binding protein that mediates translational repression t
223 or receptor A (PDGFRA), as well as novel RNA-binding protein interactors ZC3H14 (zinc finger CCCH-typ
225 our results showed increased binding of RNA-binding protein CUGBP1 with occludin and E-cadherin gene
226 CRISPR knockout of LIN28B-an oncofetal RNA-binding protein exerting diverse effects via negative re
227 (dCas9)-based CARRY (CRISPR-assisted RNA-RNA-binding protein [RBP] yeast) two-hybrid assay to assess
228 ntify and characterize a conserved SMALL RNA-BINDING PROTEIN 1 (SRBP1) family that mediates non-cell-
234 ere, we report the identification of the RNA-binding protein HuR/ELAVL1 as a central oncogenic driver
235 a, and of HBL-1 for lin-29b, whereas the RNA-binding protein LIN-28 coordinates LIN-29 isoform activi
236 teomic analyses, we demonstrate that the RNA-binding protein LIN28B, which is developmentally express
242 rexcitability and mislocalization of the RNA-binding protein TDP43 are highly conserved features in a
247 The human genome encodes for over 1,500 RNA-binding proteins (RBPs), which coordinate regulatory eve
248 (MLOs), which majorly consist of RNA and RNA-binding proteins and are formed via liquid-liquid phase
251 the human genome that are recognized by RNA-binding proteins (RBPs), generated as part of the Encycl
253 poral gene regulation is often driven by RNA-binding proteins that harbor long intrinsically disorder
256 taining complexes reproducibly contained RNA-binding proteins that were previously found associated w
257 at three maternally deposited Drosophila RNA-binding proteins (ME31B, Trailer Hitch [TRAL], and Cup)
260 ndividual guide RNAs (gRNA), we identify RNA-binding proteins (RBPs) that influence the formation of
264 c finger (TZF) domains are found in many RNA-binding proteins (RBPs) that regulate the essential proc
266 ablish that non-amyloid self-assembly of RNA-binding proteins can drive a form of epigenetics beyond
267 In this study, we used TRIBE (targets of RNA-binding proteins identified by editing) as an approach t
269 evised a cell-based functional screen of RNA-binding proteins using a let-7 sensor luciferase reporte
270 ating evidence suggests participation of RNA-binding proteins with intrinsically disordered domains (
271 s and are enriched with binding sites of RNA-binding proteins, RNA structure-changing variants and tr
272 such as trypanosomes depends heavily on RNA-binding proteins that influence mRNA decay and translati
273 RG/RGG and RSY regions in numerous other RNA-binding proteins suggests that the interaction of TNPO1
275 (fused in sarcoma) are aggregation-prone RNA-binding proteins that in ALS can mislocalize to the cyto
276 ition for binding sites among protective RNA-binding proteins and decay factors, PTBP1 promotes displ
277 We additionally show that the related RNA-binding proteins hnRNPF and hnRNPH bind directly to tRF-
278 ogenesis is tightly regulated by several RNA-binding proteins, including Lin28A/B, which represses le
280 agile X protein family consists of three RNA-binding proteins involved in translational regulation.
281 at RsmA associates with and that the two RNA-binding proteins can exert regulatory effects on common
283 c condensate that consists of ubiquitous RNA-binding proteins, revealing an unanticipated mechanism f
284 degraded by the proteasome, we uncovered RNA-binding proteins as high-confidence substrates that are
285 ures global structural features, such as RNA-binding-protein binding sites and reactivity differences
286 Finally, we observed a DNV burden in RNA-binding-protein regulatory sites (OR = 1.13, 95% CI 1.1-
287 show that fission yeast Mso1 is also a Sec1-binding protein and Mso1 and Sec1 localize to the divisi
288 on protein A (RPA), a major eukaryotic ssDNA-binding protein, is essential for all metabolic processe
292 s of FliY, where the l- enantiomer-substrate-binding protein complex interacted more efficiently with
293 e identification of membrane heparan sulfate-binding proteins is challenging because of their low abu
296 n replacement of the TFIID complex with TATA-binding protein (TBP), and PRO-seq experiments revealed
298 binding proteins PTBP1 (polypyrimidine tract-binding protein 1) and HNRNP L (heterogeneous nuclear ri
299 t expression of the NKG2D ligand ULBP2 (UL16-binding protein 2) is associated with bacterial degradab
300 ) can form heterodimers with small vasohibin-binding protein (SVBP) and were recently shown to regula