ライフサイエンスコーパス: -deprived

1 These IL-15-deprived CD8(+) T cells did not acquire the phenotype of

2 during intestinal colonization from the O(2)-deprived lumen to oxygenated tissues.

3 the numbers and suppressive capacity of IL-2-deprived Tregs with striking increases in CD25, CTLA-4,

4 in Matrigel(R) culture, whereas miR-199a-5p-deprived cells exhibited enhanced angiogenesis in vitro.

5 sponse and induction of MMP-1 in miR-199a-5p-deprived HMECs.

6 Surprisingly, IL-7-deprived diabetogenic T(E/M) cells remained present in t

7 The VAD mice were fed with a vitamin A-deprived diet after birth.

8 The vitamin A-deprived rod outer segments were 60% to 70% the length a

9 Unlike bleaching adaptation, the vitamin A-deprived rods maintained near normal saturating (dark) c

10 Contrasting phototransduction in vitamin A-deprived Xenopus rods with phototransduction in constitu

11 an mTORC1-dependent mechanism in amino acid-deprived cells.

12 reduced charging of tRNA(Gln) in amino-acid-deprived cells also leads to specific depletion of prote

13 Treating amino-acid-deprived cells with exogenous glutamine or glutaminase i

14 Connectivity was decreased in activity-deprived circuits by functional silencing of synapses, w

15 nsitive LNCaP cells under basal and androgen-deprived conditions.

16 Eligible androgen-deprived men were randomly assigned to one of four daily

17 ssion of androgen response genes in androgen-deprived conditions.

18 prostate cancer progression and in androgen-deprived CRPC cells, suggesting that CRPC possesses an e

19 (ROS), p53 levels and cell death in androgen-deprived CRPC cells.

20 a population of enhancer modules in androgen-deprived cultures showed nucleosome-depleted regions (ND

21 In androgen-deprived men, neither venlafaxine nor soy proved effecti

22 me activities also were observed in androgen-deprived tumors, consistent with pAKT-dependent HK2 prot

23 ways, pAKT levels were increased in androgen-deprived tumors.

24 ashes occur in approximately 80% of androgen-deprived men.

25 ferent metastases in the context of androgen-deprived metastatic prostate cancer.

26 mphocytes recruited into regressing androgen-deprived tumors by C-X-C motif chemokine 13 (CXCL13), a

27 dy we explore AR function under the androgen-deprived conditions characteristic of CRPC.

28 in maintaining the AR pathway under androgen-deprived conditions in castration-resistant prostate can

29 Under androgen-deprived conditions, NDRs at the TMPRSS2 enhancer were m

30 te epithelial (LHSR-AR) cells under androgen-deprived conditions.

31 d for CRPC cell proliferation under androgen-deprived conditions.

32 L-arginine-deprived T cells upregulated system L amino acid transpo

33 ASNS by small-interfering RNAs in asparagine-deprived media led to growth inhibition in both androgen

34 n kinase A activity is abnormal in astrocyte-deprived neurons but restored by TSP1, so protein kinase

35 By investigating BBS12-deprived retinal explants and the Bbs12(-/-) murine mode

36 system (T3SS) at 37 degrees C under calcium-deprived conditions.

37 CO formation in the typically CO-deprived center region of autosomes leads to premature l

38 from 8-week-old cesarean-derived, colostrum-deprived (CDCD) pigs allocated to the following 5 inocul

39 Here, colostrum-deprived calves persistently infected with HoBi-like pes

40 o the inactivating interaction of the copper-deprived N-metal binding extension with the headpiece do

41 )-MLKL necrosis pathways potentiated cystine-deprived necrosis.

42 alpha and MEKK4 dramatically reduces cystine-deprived death.

43 Compared to vitamin D-deprived mice, its moderate supplementation reduced the

44 documented reduced light sensitivity by DHA-deprived retinas.

45 yze photoreceptor health and function in DHA-deprived retinas using the Mfsd2a knock-out mouse as ani

46 ransfusion into recipient animals, these dox-deprived mature megakaryocytes generated functional plat

47 tes stresses generated by E2 in long-term E2-deprived cells that trigger apoptosis.

48 on of EGFR upon Src overexpression under EGF-deprived conditions, further supporting this model-gener

49 h's largest ecosystem, are especially energy-deprived systems.

50 in order to find and consume food in energy-deprived states.

51 Specifically, energy-deprived anaerobes overwhelmingly rely upon the higher A

52 ytic activator PFKFB3, rendering them energy-deprived, ROS- and autophagy-deficient, apoptosis-sensit

53 EF-2K are critical for survival under energy-deprived conditions and is implicated in a variety of es

54 t of BKM120 and fulvestrant against estrogen-deprived ER(+) xenografts but not LYN(D189Y)-expressing

55 d IGF-1 promotes wound repair in an estrogen-deprived animal model, the ovariectomized (Ovx) mouse, p

56 ressed in non-oviduct tissue and in estrogen-deprived oviduct by a strong repressor site located from

57 sions were also seen in a long-term estrogen-deprived breast model, where significant downregulation

58 Long-term estrogen-deprived MCF-7:5C cells were used to model the postmenop

59 -induced apoptosis in the long-term estrogen-deprived MCF7:5C cells.

60 However, in experience-deprived cortex, a much greater proportion of spines lac

61 r to the emergence of face domains, but face-deprived monkeys did not, indicating that face looking i

62 catastrophe and rapid death of growth factor-deprived cells.

63 sed higher levels of BIM under growth factor-deprived conditions and reduced Mcl-1 on stimulation.

64 Elafin is induced in growth factor-deprived HMECs as they enter a quiescent (G0) state, sug

65 a caspase-dependent manner in trophic factor-deprived sensory axons and was required for this in vitr

66 male-male mounting (MMM) behaviour in female-deprived desert locust males infected with the entomopat

67 ary fiber deprivation, together with a fiber-deprived, mucus-eroding microbiota, promotes greater epi

68 ation of endothelial alk1 expression to flow-deprived arteries fails to rescue Alk1 activity or norma

69 Fluid-deprived Sprague-Dawley rats acquired a strong CTA [via

70 Food-deprived flies reduce the gain of a visual-motion-sensit

71 en it encounters food, and animals in a food-deprived state slow even more than animals in a well-fed

72 n the ASH chemosensory neurons to allow food-deprived animals to delay response to the aversive stimu

73 The slowing responses of well-fed and food-deprived animals in the presence of food represent disti

74 ehension was only evoked in trained and food-deprived animals, suggesting that a motivation-gated mot

75 files of AGRP neurons from well-fed and food-deprived young adult mice.

76 that signal food delivery when rats are food-deprived can substantially potentiate feeding later when

77 ured under two motivational conditions: food-deprived rats given standard chow or ad libitum-fed rats

78 y different in the fed vs. fasted (>8 h food-deprived) state.

79 cial for marine bacteria, especially in food-deprived environments of the deep sea.

80 visual wide-field motion was reduced in food-deprived flies.

81 drives a distinct foraging strategy in food-deprived larvae.

82 tion nearly eliminates acute feeding in food-deprived mice.

83 ad libitum-maintained rats, and chow in food-deprived rats, but only at the 30-ng dose.

84 all of whole-body energy expenditure of food-deprived mice, similarly as seen by leptin treatment.

85 oinjected into the ACC, OFC, and DMS of food-deprived rats just prior to operant learning sessions.

86 EXPERIMENT 1: Five groups of overnight food-deprived male Sprague Dawley rats were injected with exe

87 (1) Overnight food-deprived rats were presented with a 10% sucrose solution

88 In this setting, food-deprived rats suppress eating when presented with a tone

89 cular [4V] application of leptin to the food-deprived animal, before TRH injection, yields a substant

90 pid metabolism were up-regulated in the food-deprived animals, with a novel class of taurine-containi

91 ulating peptide hormone secreted by the food-deprived stomach.

92 in previous studies from 18 monocularly form-deprived and 32 normal monkeys reared under ordinary lab

93 ively analyzed in visual area 2 (V2) of form-deprived macaque monkeys.

94 refractive errors in the two groups of form-deprived monkeys, either with or without foveal ablation

95 ed monkeys were more hyperopic than the form-deprived eyes of the normal-light-reared monkeys.

96 tropias, and in 6 of these monkeys, the form-deprived eyes were more hyperopic than their fellow eyes

97 In eight of these form-deprived monkeys, the fovea and most of the perifovea of

98 Infecting glucocorticoid-deprived cells with influenza A virus disrupted the norm

99 Glucose-deprived melanoma cells depend on both oxidative phospho

100 ollected from cells under normal and glucose-deprived conditions, estimating the relative flux change

101 p27 levels and suppressed basal and glucose-deprived levels of autophagy in cardiomyocytes in vitro.

102 s issue, we analyzed secretomes from glucose-deprived cells, which revealed up-regulation of multiple

103 apoptosis by promoting autophagy in glucose-deprived cardiomyocytes in vitro and in post-myocardial

104 o be three times as rapid as that in glucose-deprived cells.

105 oss of cell viability in a subset of glucose-deprived melanoma cells, but synergizes with acetate to

106 was prebound with Sirt2 in serum or glucose-deprived cells, and the complex dissociated following in

107 e effects were evaluated with oxygen/glucose-deprived and control neuronal cells in vitro.

108 Xe-ELIP delivery to oxygen/glucose-deprived neuronal cells improved cell viability in vitro

109 The glucose-deprived PTEN null cells were found to continue global g

110 embly after readdition of glucose to glucose-deprived cells are controlled by the glycolysis flow.

111 After readdition of glucose to glucose-deprived cells, glucose-dependent V1Vo reassembly was pr

112 e and after readdition of glucose to glucose-deprived cells.

113 Beginning 12 h after treatment, glucose-deprived human hepatocellular carcinoma (HepG2) cells de

114 Viral yield in glutamine-deprived cells or in cells treated with an inhibitor of

115 al transcription, was decreased in glutamine-deprived cells, which corresponded with a dramatic reduc

116 kinase allowed LC3-II induction in glutamine-deprived cells.

117 paragine further proved crucial in glutamine-deprived ECs to restore protein synthesis, suppress ER s

118 sole eIF2alpha kinase of yeast, in histidine-deprived cells.

119 cally integrated analyses showed how hormone-deprived LNCaP cells could transdifferentiate to a nonma

120 P cells cultured for long periods in hormone-deprived conditions.

121 ning the survival of the cells under hormone-deprived conditions.

122 R transcriptional program even under hormone-deprived conditions.

123 me efficiently reactivated within the immune-deprived nervous tissue.

124 of Neutravidin in undiluted, immunoglobulin-deprived human serum samples.

125 educed V-ATPase proton transport in inositol-deprived wild-type cells.

126 l imaging were significantly larger in input-deprived than normal input single-digit regions and were

127 itro and reversed anemia progression in iron-deprived mice.

128 PB(nu)) also mediate iron delivery into iron-deprived cells.

129 the growth of plants maintained in the iron-deprived medium.

130 sis of mutant and parental strain under iron-deprived conditions indicated a role of ALL1 in iron hom

131 ucella abortus 2308 during growth under iron-deprived conditions, and mutational studies indicate tha

132 rn blot analysis following growth under iron-deprived conditions.

133 It has been demonstrated in mice that LC-deprived epithelia are rapidly replenished by short half

134 The least-deprived patients are almost twice as likely to be refer

135 An increase in MS odds was seen in the least-deprived quintile (OR = 2.46, 95% CI = 1.40-4.24), but n

136 e in admissions over time, whereas the least-deprived quintile had the lowest increase.

137 (95% CI, 39.5-41.5) compared with the least-deprived quintile, at 23.0 admissions per 1000 children

138 d the depressive behavioral profile of light-deprived rats.

139 oma slowed down tumor growth in a lymphocyte-deprived environment but promoted immune escape in a lym

140 their ability to proliferate under magnesium-deprived situations and under anchorage-independent grow

141 by evidence of an increase in ROS in matrix-deprived cells in the luminal space of mammary acini, an

142 rvival when apoptosis is inhibited in matrix-deprived cells.

143 cer-spheroids leads to death of inner matrix-deprived cells, whereas matrix-attached cells are resist

144 protection from ferroptosis of inner, matrix-deprived cells.

145 a critical role of NRF2 in protecting matrix-deprived cells from ferroptosis.

146 evel of ubiquitinated ELK-1 rises in mitogen-deprived cells and falls upon mitogen stimulation or onc

147 riate behavioral training enables monaurally-deprived adult humans to exploit both of these adaptive

148 This may be because more-deprived patients are less suitable for a trial-as a res

149 s of specialist referral in people from more-deprived backgrounds.

150 in people of non-white ethnicity and of more-deprived backgrounds.

151 ral was less likely for patients in the more-deprived quintiles compared with the least deprived (IMD

152 The most-deprived quintile had the greatest increase in admission

153 Admissions from the most-deprived quintile had the highest overall rate of admiss

154 the highest increase in patients in the most-deprived quintile.

155 a large scale within 30 min to a switch to N-deprived conditions turning on a largely gluconeogenic m

156 In contrast with N-deprived cells, the TAGs in hypoxic cells were enriched

157 Performance losses when nap-deprived are not recovered during subsequent overnight s

158 for some small negative effects in nicotine-deprived participants.

159 We collected ERPs from 222 non-nicotine-deprived smokers (101 women) while they watched a slides

160 is suppressed when pt4 mutants are nitrogen-deprived, possibly the result of compensation by PT8, a

161 es taking place in the membranes of nitrogen-deprived E. oleoabundans, including lipid metabolism, pr

162 ressure (20% (deprived) compared to 11% (non-deprived), difference: 9.0% (95%CI: 4.7%-13.4%)).

163 were either nicotine deprived (n = 12), non-deprived (n = 12) or deprived but were allowed to smoke

164 matrix (ECM) degradation in deprived and non-deprived V1.

165 mapping and compared BEN between chronic non-deprived smokers and non-smoking controls.

166 nist muscimol could alter food intake in non-deprived rats.

167 ndomised evidence exists among adults in non-deprived settings.

168 ive for the compensatory potentiation of non-deprived inputs.

169 erse occlusion, inactivation of only the non-deprived (fellow) eye for 10 days produced a complete re

170 al-cortex-dependent behavior through the non-deprived eye (NDE) during deprivation, and enabled enhan

171 d exhibit precocious potentiation of the non-deprived eye inputs.

172 on of plasticity at synapses serving the non-deprived eye may reflect selectivity for synapses with a

173 ved-eye response without a change in the non-deprived eye response, NR2A-knockout mice fail to exhibi

174 delayed strengthening of inputs from the non-deprived eye.

175 otentiation of the pathway served by the non-deprived eye.

176 Notch-deprived 4C T cells had preserved early steps of activat

177 Notch-deprived myelin-reactive T cells had preserved activatio

178 Notch-deprived T cells showed markedly decreased production of

179 Although Notch-deprived T cells proliferated and expanded in response t

180 Both CD4(+) and CD8(+) Notch-deprived T cells had preserved expansion in lymphoid org

181 lmonary leukocyte cultures from T cell Notch-deprived mice produced less IFN-gamma, IL-5, and IL-13 t

182 However, Notch-deprived alloreactive CD4(+) T cells retained significan

183 However, Notch-deprived T cells failed to accumulate in the CNS after i

184 row chimeras increased accumulation of Notch-deprived T cells in the CNS after immunization but did n

185 ients of wild-type Tconv combined with Notch-deprived versus wild-type Tregs.

186 Additionally, two fasted groups were nurse-deprived for two cycles before being euthanized at postn

187 proliferation of cancer cells in a nutrient-deprived tumor microenvironment.

188 cts in insulin receptor mutants and nutrient-deprived animals.

189 to resist extreme environmental and nutrient-deprived conditions.

190 icroenvironment is characterized by nutrient-deprived conditions in which the cancer cells have to ad

191 pancreatic cancer metabolism during nutrient-deprived conditions.

192 es from lipid-induced damage during nutrient-deprived or replete states.

193 m the selective pressure of a harsh nutrient-deprived microenvironment.

194 by its association with Beclin1 in nutrient-deprived cells, our studies revealed that HCV-mediated a

195 hat UCP2 expression is increased in nutrient-deprived murine and human islets.

196 at could restore blood perfusion in nutrient-deprived regions where angiogenic resources are most nee

197 Importantly, DCAP kills nutrient-deprived microbes and sterilizes bacterial biofilms.

198 exploration-exploitation trade-off: nutrient-deprived flies focus on specific patches while satiated

199 nd support proliferation under some nutrient-deprived conditions.

200 ents, display phenotypes similar to nutrient-deprived and Tor mutant larvae.

201 that exosomes supply amino acids to nutrient-deprived cancer cells in a mechanism similar to macropin

202 ve mTORC1 signalling in cells under nutrient-deprived conditions and neonatal lethality in mice, whic

203 tion of lipids, or lipophagy, under nutrient-deprived conditions, and FXR inhibited this response.

204 ular survival and homeostasis under nutrient-deprived conditions.

205 phagous fungi and occurs only under nutrient-deprived conditions.

206 ung by diverting blood flow away from oxygen-deprived areas towards regions rich in O2.

207 s miRNA mediates immunosuppression in oxygen-deprived regions of tumors where cancer stem-like cells

208 y to selectively induce cell death in oxygen-deprived tissue such as tumors.

209 sed levels of alginate in response to oxygen-deprived conditions.

210 When seedlings were oxygen-deprived, the frequency of ribosomes at the start codon

211 We found that P-deprived pnp mutants develop aborted clusters of lateral

212 These new observations for pattern-deprived animals provide an anatomical basis for the wel

213 o the nucleus and induced specifically in Pi-deprived roots and shoots.

214 terning, and for stem-cell maintenance in Pi-deprived roots.

215 induction, respectively, in the roots of Pi-deprived seedlings, whereas Pi deficiency-mediated induc

216 e genes in both the genotypes grown under Pi-deprived condition, the abundance of LmPAP1 transcripts

217 to PI5P-containing liposomes but not to PI5P-deprived liposomes or PI-containing liposomes.

218 in autophagosomes in IMCD cells of potassium-deprived rats by immunogold electron microscopy.

219 gnotobiotic mice recapitulated the prebiotic-deprived hypertensive phenotype, including cardiac manif

220 ll antigen receptor repertoire in progenitor-deprived thymus grafts implied that many thymocytes were

221 Here, we show that a designer protein-deprived diet enriched in free essential amino acids can

222 lementation suppressed miR395 induction in S-deprived plants (ii) miR395 is induced in Arabidopsis se

223 al role in the transport of SO(4)(2-) into S-deprived cells.

224 lcisome formation compared with wild-type, S-deprived cells and dies more rapidly than wild-type cell

225 Under S-deprived conditions, absence of FDX5 causes a distinct d

226 trout, Salmo trutta , from Lake Mjosa (a Se-deprived lake) and Lake Losna (a reference lake), Norway

227 reminiscent of sperm isolated from selenium-deprived rodents or from mice specifically lacking mitoc

228 in two distinct cortical regions: a sensory-deprived region characterized by a decrease in inhibitor

229 required for plastic adjustments in sensory-deprived cortex.

230 rgely to layer I of barrel cortex in sensory-deprived rats.

231 1 significantly elevated proteins in sensory-deprived synapses, 22 of which were validated by immunob

232 reveal that in the visual cortex of sensory-deprived mice, dendritic spine enlargement correlates wi

233 from a sensory modality can recruit sensory-deprived cortical areas to process information from the

234 r is suppressed in growth-arrested and serum-deprived cells, suggesting that end-joining activity in

235 Furthermore, serum-deprived cells in culture show an upregulated EGFR/JAK3/

236 ession in CD230/PrP(C) was observed in serum-deprived cells in association with increased generation

237 duction of Prx III mRNA and protein in serum-deprived human cardiac fibroblasts.

238 the liver of fasted rats as well as in serum-deprived mouse embryo fibroblasts lacking both 4E-BP1 an

239 tenance of Mcl-1 protein expression in serum-deprived Tsc2(-/)(-) cells are dependent largely on the

240 ributes to the apoptotic resistance of serum-deprived Tsc1/2-deficient cells in part by increasing th

241 t anti-apoptotic effects of PDGF-BB on serum-deprived ST88-14 cells can be inhibited by W7, implicati

242 70% of maximal in amino acid replete, serum-deprived 293E cells.

243 Sleep-deprived (Sleep-Dep) rats were compared with yoked force

244 Sleep-deprived and fatigued doctors pose a safety risk to them

245 even though they were starting from a sleep-deprived baseline, suggesting that sleep homeostasis was

246 We used our in vitro model and sleep-deprived animals to map the metabolic pathways activated

247 atterns in mice, under both normal and sleep-deprived conditions.

248 Control and sleep-deprived mice were euthanized at 12 noon and processed f

249 f the deterioration of signals made by sleep-deprived honey bees and humans is generalizable, then im

250 sulin insensitivity, while chronically sleep-deprived individuals are more likely to develop obesity,

251 hus, eveningness in obese, chronically sleep-deprived individuals compounds the cardiovascular risk a

252 nts (experiment 1, n = 39), and during sleep-deprived wakefulness and non-rapid eye movement sleep (e

253 Accordingly, HSCs from sleep-deprived mice have higher levels of SOCS genes expressio

254 egions involved in attention lapses in sleep-deprived and well-rested adults.

255 ediately normalize pain sensitivity in sleep-deprived animals, without affecting sleep debt.

256 dFB neurons in sleep-deprived flies tend to be electrically active, with high

257 cantly depolarized in Hcrt neurones in sleep-deprived mice as compared with controls (P < 0.01, t tes

258 nhances neurogenesis in hippocampus in sleep-deprived mice.

259 ficantly enhances NPC proliferation in sleep-deprived mice.

260 storation normalizes reward seeking in sleep-deprived mice.

261 mance-restoring effects of caffeine in sleep-deprived subjects.

262 on challenge the claim of increasingly sleep-deprived societies.

263 esembles the cortical transcriptome of sleep-deprived mice, and plastic changes as reflected by AMPA

264 ly greater density of spines in CA1 of sleep-deprived mice, driven primarily by greater numbers of th

265 of caffeine on the PVT performance of sleep-deprived subjects and, therefore, can be used for determ

266 or vigilance task (PVT) performance of sleep-deprived subjects.

267 ndependent dataset involving partially sleep-deprived participants.

268 ivation, and reduced aggression places sleep-deprived flies at a competitive disadvantage for obtaini

269 Here we show that sleep-deprived honey bees (Apis mellifera) exhibit reduced pre

270 onal stimuli judged as pleasant in the sleep-deprived group, the extent of which exclusively correlat

271 signing were 4.5 times higher for the sleep-deprived participants than for the rested participants.

272 Neurocognitive tasks may tax the sleep-deprived resident more than well-learned technical skill

273 minergic signaling associated with the sleep-deprived state.

274 iotics mix (ABX) or BDPP or both, were sleep-deprived at the end of a fear conditioning training sess

275 d collected from participants who were sleep-deprived, treated with sodium oxybate, or allowed to sle

276 P1) resulted in stunted seedlings in sucrose-deprived medium.

277 Sulfur-deprived cells of Chlamydomonas reinhardtii have been sh

278 d to sustained hydrogen production in sulfur-deprived Chlamydomonas reinhardtii cultures.

279 Moreover, the data suggest that sulfur-deprived cells accumulate proteins with fewer sulfur-con

280 scule degeneration does not occur in sulphur-deprived mtpt4 plants.

281 f reactive oxygen/nitrogen species in target-deprived neurons.

282 ammation in the long-term survival of target-deprived afferent neurons.

283 We revealed that TE-deprived ICMs derived from 32-cell blastocysts are still

284 rhizi uredospores, detached leaves of urease-deprived plants developed a significantly higher number

285 the protein extracts from transgenic urease-deprived plants than in extracts from non-transgenic con

286 Water-deprived animals had to learn to localize an object with

287 Water-deprived rats initially received a single odor-toxicosis

288 In Experiment 1, water-deprived rats had 5-min access to saccharin followed by

289 s for reward valuation we had food and water-deprived subjects make risky choices for money, food, an

290 firing in the LHb of freely behaving, water-deprived rats before and after an ethanol-induced (1.5 g

291 lectron micrographs revealed that both water-deprived and NaCl-treated plants had elevated osmium acc

292 response similarly to that observed in water-deprived rats.

293 we observed increased host-feeding in water-deprived wasps despite honey availability.

294 s showed that the host-feeding time of water-deprived wasps doubled compared to water-fed individuals

295 After recovery, water-deprived rats were presented with taste stimuli in an ex

296 or was only observed when animals were water-deprived but not under food- or salt-depleted conditions

297 ay kinetics and larger amplitudes in whisker-deprived barrels than those in nondeprived barrels in ag

298 somatosensory cortex of unilaterally whisker-deprived adult mice, the current study demonstrates that

299 Yeast-deprived males exhibited attenuated female-induced night

300 reduced sleep in normally fed but not yeast-deprived males.