ライフサイエンスコーパス: -fold reduction in

1 ubstitution in P2 caused approximately 1,000-fold reduction in CheA-CheY binding affinity, while Ala

2 vergent metabolic trajectories, with a 1,000-fold reduction in serum secondary bile acids, which was

3 was prevented, with at least a 500- to 1,000-fold reduction in the efficiency of initiating gene expr

4 IFN induction coincided with a 100- to 1,000-fold reduction in virus titer, supporting the hypothesis

5 Despite a 10,000-fold reduction in gut bacterial load and long-lasting di

6 this double mutant strain exhibited a 10,000-fold reduction in mouse bladder colonization 24 h after

7 Ablation of drl-1 led to a >10,000-fold reduction in Orsay virus RNA levels, which could be

8 hat this elevated pK(a) results in a >10,000-fold reduction in the rate constant for oxidations of th

9 of HIPR-1 resulted in a greater than 10,000-fold reduction in viral RNA, which could be rescued by e

10 NA (10 ng/muL), we demonstrated over 100,000-fold reduction in lambda-DNA concentration.

11 Mutations of these residues cause an 18,000-fold reduction in catalytic rate in vitro and large-scal

12 utant of pol beta was shown to have a 29,000-fold reduction in polymerization rate with no reduction

13 Compared to the C:G pair, a 1.9- and 79,000-fold reduction in Dpo4 efficiency was observed for termi

14 e-molecule force spectroscopy revealed a 2.1-fold reduction in the normalized force required to unfol

15 4, but longer spacers (x >/= 5) lead to a 10-fold reduction in affinity.

16 nserved structure proximal to A1 caused a 10-fold reduction in all transcripts that utilized A1.

17 in raster mode and discuss advantages (a 10-fold reduction in analysis time) and challenges (suitabl

18 crease in deposition rate together with a 10-fold reduction in analyte consumption while ensuring les

19 nificantly reduced T-cell responses and a 10-fold reduction in anti-EcAII IgG titers relative to the

20 the diacylglycerol lactones showed only a 10-fold reduction in binding affinity with the triple argin

21 r numbers are maintained, but there was a 10-fold reduction in committed PreproB-lymphoid progenitors

22 orded in marine sedimentary deposits as a 10-fold reduction in deposition rates of Eel-derived sedime

23 nt communities: a slope of -0.5 depicts a 10-fold reduction in diversity for every 100-fold increase

24 h assay component resulted in more than a 10-fold reduction in fluorescence background and improved t

25 The S225A mutant exhibited a 10-fold reduction in genome replication, whereas the S225D

26 However, there was a 10-fold reduction in hematologic ADRs among variant carrier

27 A 10-fold reduction in IL-6 and a 5-fold decrease in hyaluron

28 The altered gp5/Trx exhibits a 10-fold reduction in its ability to support growth of T7 ph

29 omising cellular energetics and causing a 10-fold reduction in lytic phage yield.

30 cohort study, these changes resulted in a 10-fold reduction in measurements of viral diversity.

31 150-fold improvement in sensitivity and a 10-fold reduction in peak width in the following microchip

32 hoablatant (S225A) mutation resulted in a 10-fold reduction in replication and a perinuclear restrict

33 ts using fluorescence anisotropy showed a 10-fold reduction in RNA binding in the G100E and G104E mut

34 lants overexpressing AOX exhibited over a 10-fold reduction in ROS accumulation compared with wild-ty

35 e preparation of maltenes by exhibiting a 10-fold reduction in sample processing time, compared to th

36 d peak-calling pipelines we demonstrate a 10-fold reduction in signals in regions common to the black

37 Tandem mass spectrometry revealed a 10-fold reduction in the expression of olpB, which may expl

38 the child and both parents resulted in a 10-fold reduction in the number of potential causal variant

39 independently associated with more than a 10-fold reduction in the risk of a complicated course (rela

40 Finally, we report that a 10-fold reduction in TRF2 affects the regulation of telomer

41 mmunized with such conjugates displayed a 10-fold reduction in viral load.

42 ted hazard ratio: 0.12; p = 0.001) and a ~10-fold reduction in cardiovascular mortality (adjusted haz

43 mice was associated with a approximately 10-fold reduction in lung virus titer and protection agains

44 tution or deletion of Phe 567 leads to a >10-fold reduction in enzymatic activity, underscoring its i

45 ble data, by treatment day 9 there was a >10-fold reduction in viability in 100% (24/24) of cases and

46 n the Mk3(-/-) mice was accompanied by a >10-fold reduction in viral lung titer and an increase in th

47 earing either substitution showed an over 10-fold reduction in aminoacylation activity.

48 fission intermediates that contributed to 10-fold reduction in bulk rates of membrane fission.

49 to 100-fold in TALE-R activity and up to 10-fold reduction in TALEN activity compared with target se

50 e > 200-fold decreases in runtime and ~ 5-10-fold reductions in cost relative to CPUs.

51 uction in virus yield but a significant (>10-fold) reduction in HSV-1 released through the apical sur

52 ibroblasts from either subject, despite a 10-fold-reduction in TRNT1 protein levels in fibroblasts of

53 A 10-100-fold reduction in binding of IgE from allergic subjects

54 ent a death phase that resulted in a ~50-100-fold reduction in the number of viable cells.

55 The CipA deletion mutant exhibited a 100-fold reduction in cellulose solubilization rate, althoug

56 f DENV in vitro and in vivo, marked by a 100-fold reduction in DENV load in murine lymph nodes.

57 St14 hypomorphic mice, which have a 100-fold reduction in intestinal matriptase mRNA levels, dis

58 A 100-fold reduction in neutrophil infiltration was observed i

59 of L. major, and this correlated with a 100-fold reduction in parasite load.

60 ated a 50% reduction in testis weight, a 100-fold reduction in sperm number and the presence of abnor

61 moval of BsCBM66 from SacC results in a ~100-fold reduction in activity against levan.

62 be simultaneously reprogrammed, with an ~100-fold reduction in costs of raw materials compared to tho

63 Our simulations predict an ~100-fold reduction in heating compared with previous designs

64 he application allows for an approximate 100-fold reduction in the data processing time compared to m

65 thium-binding site results in a dramatic 100-fold reduction in the inhibitory constant as compared wi

66 of KRIT1(L717,721A), which exhibited a >100-fold reduction in HEG1 affinity.

67 This method, Tn5mC-seq, enables a >100-fold reduction in starting material relative to conventi

68 ss of hydrolase activity, resulted in a >100-fold reduction in the efficiency of UCHL1(GLU7ALA) relat

69 ion of rod CNG channels and a subsequent 100-fold reduction in rod responses, while preserving normal

70 icacy and selectivity, yielding a 20- to 100-fold reduction in population for cells containing a cogn

71 solution of acute infection and a 10- to 100-fold reduction in the number of bacteria and tissue-infi

72 phosphorylation and also caused a 10- to 100-fold reduction in virus production, along with decreased

73 a and bacteremia, as evidenced by a 100-1000-fold reduction in bacterial burden following challenge.

74 The Ab treatment led to a 1000-fold reduction in B cell number that lasted 6 wk.

75 mutation in streptavidin that causes a 1000-fold reduction in biotin binding affinity without disrup

76 onductance by N451S, but with an almost 1000-fold reduction in apparent affinity.

77 f the PERV pol gene and demonstrated a >1000-fold reduction in PERV transmission to human cells, usin

78 imized correctly, result in a more than 1000-fold reduction in biomaterials and cells consumption whe

79 f 1 novel variant, E141G-CaM, revealed an 11-fold reduction in Ca(2+)-binding affinity and a function

80 ain cleavages showed approximately 4- and 11-fold reductions in A2 subunit generation and approximate

81 10G and 9G variants, the latter having a 13-fold reduction in surface expression of PorA.

82 way offers a 4-fold reduction in time and 13-fold reduction in resource requirement compared to the c

83 he hydroxylated QDs result in a dramatic 140-fold reduction in nonspecific binding relative to that o

84 NA was maintained with a 6-, >143-, and >143-fold reduction in affinity toward single C-C, A-A, and G

85 ithin the cytoplasmic compartment led to >15-fold reduction in false-positive signals and a significa

86 d-type HSV-2 infection and can lead to a 150-fold reduction in wild-type HSV-2 viral replication in c

87 transmembrane 6 also had a major effect (18-fold reduction in salmeterol affinity).

88 tin sulphate or heparan sulphate-PGs and 2.2-fold reduction in neurocan and brevican core proteins in

89 ificant reduction in hepatic I/R injury (4.2-fold reduction in the aminotransferase and a 3.5-fold re

90 y induced the greatest tumor regression (6.2-fold reduction in size compared to PBS-treated controls)

91 of several ISGs (r = -0.68; P = 0.001); a 2-fold reduction in a four-gene ISG signature predicted an

92 st this USA300 strain, resulting in only a 2-fold reduction in bacterial burden.

93 strains below, but not above, 15%, with a 2-fold reduction in energy dissipation upon microtubule de

94 uction of F5H expression but only around a 2-fold reduction in expression of other lignin pathway gen

95 nstead, we found that MVT binding caused a 2-fold reduction in F-actin's bending persistence length a

96 ificantly decreased actin turnover, with a 2-fold reduction in filament severing frequency.

97 de is reduced by 2-fold, which is due to a 2-fold reduction in hexasome unwrapping probability.

98 ciency induces, as previously described, a 2-fold reduction in mature B cells.

99 However, a 2-fold reduction in nuclear entry by PF74 did not quantita

100 by gamma-radiation doses >/=2.5kGy, and a 2-fold reduction in OTA cytotoxicity was observed.

101 However, this leads to only a 2-fold reduction in rate of incorporation at a physiologic

102 riants with a 10G repeat tract exhibited a 2-fold reduction in surface expression of PorA protein.

103 e antigen-presenting cells, resulting in a 2-fold reduction in T-cell priming.

104 emsima glycoforms, which translated into a 2-fold reduction in the level of FcgammaIIIa receptor bind

105 ematic use of PET/CT was associated with a 2-fold reduction in the number of relapses (9.6% vs. 4.2%,

106 ents, mixed models resulted in more than a 2-fold reduction in the proportion of kidneys with |bias|

107 We also detected a 2-fold reduction in the Recurrence quantification analysis

108 in the Pcat promoter mutant resulted in a 2-fold reduction in total amounts of capsule and in avirul

109 Dox + Val ISFIs showed a 2-fold reduction in tumor growth and a 27.69% increase in

110 n of endogenous Mov10 by 80% resulted in a 2-fold reduction in virus production but no discernible im

111 even in unstimulated cells and induced a ~2-fold reduction in the lateral mobility of ErbB3 homodime

112 in nuclear import rate and a approximately 2-fold reduction in nuclear residence time compared with t

113 P to 101-499 ng/mL was associated with a > 2-fold reduction in posttransplant mortality (P = 0.01) an

114 n, while on-target knockdown was improved (2-fold reduction in IC50).

115 nted in wavelet domain to achieve at least 2-fold reduction in the number of holographic measurements

116 These mutants showed a modest 2-fold reduction in cell-to-cell infection assays.

117 saccharide IgM mAb ( approximately 1.2- to 2-fold reduction in fluorescence).

118 Compared with 4,4'-o-BBV, 2-fold reductions in lower limits of detection (LOD) and q

119 deficient or CD4-depleted mice demonstrate 2-fold reductions in HIF-1alpha expression as compared to

120 A mutant exhibited a modest (approximately 2-fold) reduction in competitiveness, while the other two

121 the receptor binding site that leads to a 20-fold reduction in binding.

122 ve complex (PRC) targets, together with a 20-fold reduction in expression of fertilization independen

123 Moreover, a 20-fold reduction in Gbeta5 and RGS9-1 expression was also

124 flow over other SPROX protocols include a 20-fold reduction in the amount of total protein needed for

125 This was accompanied by a 20-fold reduction in the expression level of PAX6 and a sig

126 h a reduction of CD4(+)CD8(+) cells and a 20-fold reduction in thymic cellularity.

127 induces aggresomes despite a greater than 20-fold reduction in protein level compared to wild type.

128 und that ART was associated with a 10- to 20-fold reduction in risk for sexual transmission of HIV.

129 er to as read clouds This enables a 4- to 20-fold reduction in sequencing requirements and a 5-fold i

130 in unpredictable ways, ranging from 3- to 20-fold reductions in maximal growth rate.

131 This provector demonstrates a 200-fold reduction in transduction ability in the OFF state

132 ear-normal endonuclease activity, but a ~200-fold reduction in steady-state ATPase activity, a lag in

133 n in plasma HIV RNA levels and an almost 200-fold reduction in HIV-infected human cell numbers in mou

134 ncy, except for Arg173, which displayed a 22-fold reduction in IC(50).

135 We report here that approximately 22-fold reduction in 2D NMR data collection time for the bo

136 cantly (P < 0.001) reduced densities, a 2.25-fold reduction in sinking rates, and a higher propensity

137 etargeting system produced a greater than 25-fold reduction in total body radiation exposure relative

138 total N-nitrosamine concentration, a ~25000-fold reduction in concentration is needed between washwa

139 in mice infected with spores and led to a 26-fold reduction in lung CFU by 6 d postinfection versus n

140 A 1.3-fold reduction in the rate of transducin activation by r

141 VR+TVI was associated with an additional 2.3-fold reduction in TR grade (odds ratio [OR]: 0.44; 95% c

142 on schemes and observe that OSS provides a 3-fold reduction in average seed frequency over the best p

143 Loss of miRNAs resulted in a 3-fold reduction in binucleate hepatocytes, indicating tha

144 loss of complexity could cause more than a 3-fold reduction in fishery productivity.

145 Additionally, a 3-fold reduction in non-geminate recombination is measured

146 2D-DIGE revealed a 3-fold reduction in optic nerve neurofilaments.

147 red to the wild-type strain, also showed a 3-fold reduction in parasite burden.

148 level of primary expansion, with at most a 3-fold reduction in the case of responses to Listeria.

149 utation of one of the MDRs, MdrM, led to a 3-fold reduction in the IFN-beta response to L. monocytoge

150 nd CD103(+) DCs in the liver, results in a 3-fold reduction in the proliferative response of Ag-speci

151 CD), a sterol-chelating reagent, causing a 3-fold reduction in total cellular sterols as well as enha

152 n the putative C (coupling) motif causes a 3-fold reduction in velocity and a 6-fold reduction in pro

153 ng ability and yet have only approximately 3-fold reduction in ATPase stimulation by nucleosomes.

154 quitinome studies and show a approximately 3-fold reduction in the proportion of miscleaved peptides

155 channel function, such as a approximately 3-fold reduction in the response to cAMP.

156 The microfluidic approach showed a nearly 3-fold reduction in error as compared to previous methods.

157 ansplant mortality (P = 0.01) and a nearly 3-fold reduction in HCC recurrence (P = 0.02) compared wit

158 tance (>/=50%), altered burst proportions (3-fold reduction in the proportion of long bursts), and en

159 versus 18.5+/-3.5%), and oxidative stress (3-fold reduction in tissue malondialdehyde).

160 (2) nanocrystals (NCs) with a greater than 3-fold reduction in overpotential for electrochemical CO(2

161 one marrow iNKT numbers, we observed 2- to 3-fold reduction in the numbers of iNKT cells in the splee

162 in DeltahnRNPA2B1 cells, there was a 2- to 3-fold reduction in virus yield but a significant (>10-fol

163 3 knockdown and CRM-1 overexpression cause 3-fold reductions in PGC-1alpha target gene expression, co

164 row specificity of Apo3A at acid pH, a 13-30-fold reduction in specific activity is accompanied by re

165 the region of interest, which leads to a 30-fold reduction in the power requirement for two- or thre

166 and pulling forces that result in up to a 30-fold reduction in the threshold electric field needed to

167 ge phagosomal acidification resulted in a 30-fold reduction in USA300 expression of the staphylococca

168 ence of FliS resulted in an approximately 30-fold reduction in extracellular Hag accumulation in cell

169 We observed a >300-fold reduction in the IFN-stimulated genes (ISGs) MxA an

170 rhesus fibroblasts led to a greater than 300-fold reduction in the viral titer by 48 h but had little

171 dvantage of this assay is the more than 3000-fold reduction in radioactive waste over existing protoc

172 A 33-fold reduction in NA expression is accompanied by only a

173 e R1689H variant showed an approximately 340-fold reduction in the rate of Arg-1689 cleavage, whereas

174 PK17 and -34 results in an approximately 350-fold reduction in pollen transmission efficiency.

175 ure transcriptional termination and up to 39-fold reductions in full-length transcripts in adult mous

176 81% decrease in XT-1 mRNA, an average of 1.4-fold reduction in GAG-side chains of chondroitin sulphat

177 f the reporter genes, as suggested by a 10.4-fold reduction in L-protein RNA transcript.

178 ha-smooth muscle actin expression, and a 2.4-fold reduction in collagen I deposition.

179 ithin bulges and loops and resulted in 0.3-4-fold reduction in the measured binding affinities for di

180 and microtip electrode pairs resulted in a 4-fold reduction in nonspecific adsorption of blood cells

181 Concomitantly, we observed a 4-fold reduction in spontaneous miniature release events f

182 Dox + Val showed a 4-fold reduction in the 50% lethal dose (LD(50)) after 48

183 the AND similarity index (sgridAND) and a 4-fold reduction in the scale-dependent Lyapunov exponent

184 The pathway offers a 4-fold reduction in time and 13-fold reduction in resource

185 UBC promoter intron loss caused a 4-fold reduction in transgene expression.

186 ers were right-side out, and we observed a 4-fold reduction in transport rate.

187 of Cyp24a1 (BVE(Cyp24a1-null)) exhibited a 4-fold reduction in tumor growth.

188 on of arsB in C. jejuni resulted in 8- and 4-fold reduction in the MICs of arsenite and arsenate, res

189 of these residues leads to a approximately 4-fold reduction in k(cat) for Cu(I) oxidation.

190 y precursor population and a corresponding 4-fold reduction in CD4(+) memory cell number.

191 positions relative to the wild type had a >4-fold reduction in HI titers compared to homologous antis

192 prophylaxis achieved a highly significant, 4-fold reduction in postoperative endophthalmitis in patie

193 from these viruses exhibited only a 2- to 4-fold reduction in their dNTP utilization efficiency but

194 Glu214 to Ala or Asp caused at least a 4000-fold reduction in k(cat), with 10-fold increases in K(m)

195 plication factory formation, as well as a 42-fold reduction in virus yield in WT but not RNase L KO c

196 However, PMCA4a rescue caused a 44-fold reduction in AP-2beta, a known anti-proliferative t

197 n absence of stromal Cav-1 predicted an 11.5-fold reduction in 5-year progression-free survival.

198 duced synergistic effects, including an 11.5-fold reduction in LC50, 43% reduction in LT50 and a 78%

199 ts and allows designing libraries with a 2.5-fold reduction in required cell numbers without sacrific

200 nf6Delta cells there was a approximately 2.5-fold reduction in rRNA synthesis rate compared to WT, bu

201 es exhibited a corresponding approximate 3-5-fold reduction in cytotoxic activity [L1210 IC(50) for (

202 reduction in the aminotransferase and a 3.5-fold reduction in aspartate aminotransferase) compared w

203 d experimental conditions, we achieved a 3.5-fold reduction in nonspecific adsorption of non-target p

204 duced damage, as indicated by a relative 3.5-fold reduction in the number of dying neurons adjacent t

205 acrophages from c-Cbl(+/-) mice showed a 4-5-fold reduction in tumor phagocytosis, which was restored

206 lex mixtures such as urine combined with a 5-fold reduction in analysis time compared with the conven

207 advantages include shortened run times, a 5-fold reduction in formaldehyde concentration, a signific

208 In the model, a 5-fold reduction in infectivity (from 1.6% to 0.3%) occurr

209 in NA expression is accompanied by only a 5-fold reduction in K(b)-SIINFEKL complex cell-surface exp

210 term hematopoietic stem cells (LT-HSCs), a 5-fold reduction in LT-HSCs capable of 24-hour homing, and

211 the Npu DnaE intein to splice with only a 5-fold reduction in rate compared to the wild-type Cys+1 i

212 Instead, the absence of Nlrp3 caused a 5-fold reduction in the number of tumor-associated MDSCs f

213 fect, while dual inactivation results in a 5-fold reduction in thymocyte cellularity, accompanied by

214 in Vero cells and showed an approximately 5-fold reduction in specific infectivity, commensurate wit

215 licing but corresponded to a approximately 5-fold reduction in the accumulation of M1.

216 ground (AdT*RGE) resulted in a significant 5-fold reduction in spleen uptake and attenuated the antiv

217 ylthiobenzothiazole; APB) leads to a 3- to 5-fold reduction in TBSV replication in yeast.

218 This protocol resulted in a 50-fold reduction in material required from previous CEC me

219 ctor, whereas PMCA4b rescue resulted in a 50-fold reduction in p15 (Cyclin D1/Cdk4 inhibitor).

220 unable to produce surfactin exhibited an ~50-fold reduction in viability after oxygen depletion.

221 r Ocr monomer results in an approximately 50-fold reduction in binding affinity for a methyltransfera

222 opulations, resulting in an approximately 50-fold reduction in IL-7-dependent B lineage generative ca

223 There is also an approximately 50-fold reduction in the affinity of the R229W variant for

224 we found 39 strong terminators, yielding >50-fold reduction in downstream expression, that have suffi

225 hy caused by viable bacteria, with a peak 50-fold reduction in thymocyte numbers.

226 the expression of M80.5/protease and a 2,500-fold reduction in viral growth.

227 ate bacterial cells and their DNA with a 500-fold reduction in sample volume (from 10 to 0.02mL).

228 substrate when the enzyme suffers a 175-550-fold reduction in k(cat).

229 ered lipid homeostasis associated with a 0.6-fold reduction in the expression of the gene elongation

230 tin treatment, which was the result of a 1.6-fold reduction in mitochondrial volume density and alter

231 nd lymph node metastasis, resulting in a 3.6-fold reduction in progression-free survival.

232 in the Reb1p-binding sequence caused an 8.6-fold reduction in beta-galactosidase activity.

233 in H1650 SP cells after 2h resulting in a 6-fold reduction in AnxA2 mRNA expression and 92% decrease

234 auses a 3-fold reduction in velocity and a 6-fold reduction in processivity.

235 e the time-limiting incubation step with a 6-fold reduction in the incubation time.

236 corporation could be partly explained by a 6-fold reduction in the specificity constant of the CMP-Kd

237 ld increase in k(cat) and an approximately 6-fold reduction in the K(m) for ATP and by rendering the

238 iod, S100a9(-/-) mice displayed an average 6-fold reduction in circulating and lung-recruited neutrop

239 mples analyzed, with SERS demonstrating a 60-fold reduction in acquisition time compared with HPLC.

240 placental insufficiency/FGR, the observed 60-fold reduction in the choline/lipid ratio by (1)H MRS ma

241 Mutation of fosB or bshA caused a 16- to 60-fold reduction in fosfomycin resistance in these S. aure

242 Finally, there is more than a 600-fold reduction in the HSC pool of mice deficient in both

243 proline causes a massive approximately 6000-fold reduction in catalytic efficiency.

244 by fluorophosphonate derivatives (13- to 63-fold reduction in potency).

245 ng frequencies, whilst eliciting a 12- to 69-fold reduction in C-to-U edits in the transcriptome, and

246 ering RNAs in INS-1E cells resulted in a 1.7-fold reduction in glucose-stimulated insulin secretion.

247 ion in FABP4 transcription (P=0.049) and 2.7-fold reduction in apoptosis (activated caspase 3; P=0.04

248 rease in total dietary fat resulted in a 2.7-fold reduction in eosinophil IL-16 content among C57BL/6

249 ased from 0.05 uA to 12.1 uA there was a 3.7-fold reduction in EC(50).

250 from DGK1-overexpressing cells showed a 7.7-fold reduction in DAG kinase activity; the reduced enzym

251 Accordingly, we find modest 1.5- to 2.7-fold reductions in G.T activity upon altering the CpG co

252 ubunit generation and approximately 3- and 7-fold reductions in A1 subunit generation for the R1689H

253 A significant (2.7-fold) reduction in CD3zeta chain expression on CD3epsilo

254 HIV infection as manifested by a profound 70-fold reduction in plasma HIV RNA levels and an almost 20

255 e interval: 1.6, 10.4), and there was a 2.75-fold reduction in the median time to progression.

256 contrast, L-cIDPR displays a comparative 75-fold reduction in activity, but is only ca 2-fold less p

257 oded, a significant reduction, up to an ~750-fold reduction, in viral RNA transcripts occurred.

258 nce, metformin-treated guinea pigs had a 2.8-fold reduction in lung lesion burden and a 0.7 log decre

259 the variant allele was associated with a 3.8-fold reduction in FABP4 transcription (P=0.049) and 2.7-

260 ed a 25% reduction in homing efficiency, 3.8-fold reduction in transplantable long-term hematopoietic

261 phage lambda gpA packaging motor causes an 8-fold reduction in translocation velocity without substan

262 years, EF recovery was associated with an ~8-fold reduction in all-cause mortality (adjusted hazard r

263 f protein S, resulting in an approximately 8-fold reduction in Ki compared with TFPI alone.

264 ic efficacy in controlling mouse melanoma (8-fold reduction in tumor volume), which is associated wit

265 ential impact on SCD risk reduction (up to 8-fold reduction in the number of SCDs in the population)

266 7Q, in the HA of H7N9 virus led to 23- and 8-fold reductions in hemagglutination inhibition (HI) tite

267 Pneumococci lacking RafK showed a 50- to 80-fold reduction in expression of the raf operon genes aga

268 ) of 390 +/- 80 nM) with a 13-, 169-, and 85-fold reduction in affinity toward single C-C, A-A, and G

269 th retapamulin ointment resulted in up to 85-fold reduction in bacterial burden and a 53% decrease in

270 from isolated muscle fibers resulted in a 9-fold reduction in myoblast expansion, caused by delayed

271 However, we observed a 9-fold reduction in number of neutrophils infiltrating isc

272 nabling a single-cell detection limit, and 9-fold reduction in needed time to 5 min.

273 ion limit at the same dose, or up to a fifty-fold reduction in dose at the same resolution.

274 ep learning to augment SIM, we obtain a five-fold reduction in the number of raw images required for

275 cells in IRAK-M(-/-) mice resulted in a five-fold reduction in tumor growth as compared with tumors i

276 This allows for a four-fold reduction in contact time compared to conventional

277 lls and tumors to docetaxel, allowing a four-fold reduction in effective dose.

278 ession of MYC proto-oncogene, and up to four-fold reduction in accumulated mutations in translocated

279 ted up to 1:10, resulting in more than 5 log-fold reduction in 4 min.

280 This many-fold reduction in measurement time will enable more freq

281 1,000-fold increase in speed and a 1-million-fold reduction in cost.

282 tic-EPI-PMBN combination caused a 10 million-fold reduction in the viability of biofilm forming cells

283 ts displayed no pathology and over a million-fold reduction in replication.

284 unique cellular barcodes, we achieved a 2(n)-fold reduction in the number of arrays and quantity of r

285 mbinant mutant calmodulins exhibited several-fold reductions in calcium binding affinity.

286 of human and mouse cortical neurons with six-fold reduction in image data requirements and three time

287 f the increase in PEF energy to ensure a ten-fold reduction in De (ze, 63.7 J), activation electric f

288 Thousand-fold reductions in IgG1 titers to both Ags were observed

289 esults in central tumor necrosis and a three-fold reduction in human tumor vascular density.

290 te our approach and show it produces a three-fold reduction in working space when constructing a colo

291 se experiments reveal an approximately three-fold reduction in activation energy for ion transport at

292 Western blotting confirmed a two- to three-fold reduction in renal cortical homogenate insulin rece

293 of catalase in the brain resulting in three-fold reductions in inflammation and complete neuroprotec

294 castrated men and was associated with a two-fold reduction in area under the curve (P = .0001), alth

295 a formation by serum starvation led to a two-fold reduction in ciliogenesis in fibroblasts derived fr

296 c superhydrophobic surface can lead to a two-fold reduction in contact time compared to equivalent ri

297 fly-infested plants exhibited at least a two-fold reduction in gall formation on both stem and crown

298 those with MPO G alleles had more than a two-fold reduction in hazard of recurrence (adjusted hazard

299 There was a two-fold reduction in the amplitudes of the evoked endplate

300 A uniform two-fold reduction in (15)N/(1)H NMR signal intensities of A