ライフサイエンスコーパス: -guided

1 Using an activity-guided biochemical approach, we report the molecular ide

2 was utilized during the sensory or activity-guided identification of chavibetol as the key odorant a

3 ic, stable, and abundant target for affinity-guided delivery of anticancer drugs.

4 of individual FFR data and conventional age-guided rate-response programming.

5 .85]; p < 0.001), but not clinical algorithm-guided antibiotic therapy (-7.41 [-18.18 to 3.37]; p = 0

6 1 [0.82-1.01]; p = 0.09), clinical algorithm-guided antibiotic treatment (0.67 [0.30-1.54]; p = 0.35)

7 fter Early PCI for STEMI) trial, angiography-guided percutaneous coronary intervention (PCI) of noncu

8 Results demonstrate that combinatory AQbD-guided mass spectrometric/liquid chromatographic optimiz

9 Bioassay-guided fractionation of the source extract resulted in t

10 hibition at 256 ug/mL and underwent bioassay-guided fractionation, leading to the isolation of pentag

11 tal effects induced by MIA and for biomarker-guided approaches in preclinical psychiatric research.

12 for and responded to at least one biomarker-guided treatment, including tumors resistant to standard

13 Here we investigate whether biomarker-guided use of multiple targeted therapies, including sma

14 ul in vivo application of such a biomaterial-guided delivery of a potent gene vector in an orthotopic

15 Advanced biomaterial-guided delivery of gene vectors is an emerging and highl

16 pled MBT from N/C increase, arguing that N/C-guided down-regulation of cyclin/Cdk1 is sufficient for

17 CRISPR-Cas-guided base editors convert A*T to G*C, or C*G to T*A, i

18 Remarkably, CRISPR/Cas9-guided single-nucleotide editing demonstrated the direct

19 domized controlled telemedicine trial of CBT-guided self-help (CBT-GSH) assisted with a smartphone ap

20 troduced including programmed catalysis, CDN-guided optical and catalytic functions of nanoparticle a

21 n designing dissipative transient CDNs, CDNs-guided transcription/translation synthesis of selective

22 orthogonally triggered CDNs lead to the CDNs-guided enhanced transcription of either the DFHBI aptame

23 e ribosome t-RNA machinery leads to the CDNs-guided transcription/translation of the green fluorescen

24 treated according to the same reading center-guided T&E regimen after 3 initial monthly injections.

25 llow-up (48%) compared with physician clinic-guided follow-up (77%, P<0.001).

26 CLOSE-guided atrial fibrillation (AF) ablation is based on con

27 with paroxysmal AF, planned for first CLOSE-guided pulmonary vein isolation using a contact force ra

28 mized in a 1:1 basis to receive PVI plus CMR-guided fibrosis ablation (CMR group) or PVI alone (PVI-a

29 om-built surface profiler for performing CNC-guided microsurgery on mice.

30 h it a surge of research related to computer-guided approaches to catalyst design.

31 atistical computation and predict confidence-guided behavior.

32 f these neurons also predicts two confidence-guided behaviors: trial-by-trial time investment and cro

33 of (19)F NMR in establishing a conformation-guided drug screening system, advancing the cell- and st

34 of the training cohort, a method for contour-guided image registration was developed.

35 wide range of treatment durations in the CRP-guided group.

36 The CRISPR RNA (crRNA)-guided nuclease Cas13 recognizes complementary viral tra

37 both CRISPR RNA (crRNA) processing and crRNA-guided DNA cutting to target foreign nucleic acids.

38 prospective trial was performed assessing CT-guided lesion targeting on an abdominal phantom with and

39 provide holographic 3D guidance to assist CT-guided targeting.

40 010 and October 2019 with collimated-beam CT-guided percutaneous FICS procedures for preventive conso

41 Out-of-plane lesions pose challenges for CT-guided interventions.

42 However, the success rate of CT-guided bone biopsies for molecular analyses in mPC patie

43 We were able to perform CT-guided biopsies with histologic validation of the nonres

44 ents, of whom 216 underwent (18)F-FDG PET/CT-guided biopsy and 125 underwent CT-guided biopsy.

45 DG PET/CT-guided biopsy and 125 underwent CT-guided biopsy.

46 n The target median overall survival with CT-guided percutaneous irreversible electroporation was exc

47 ed two potent peptides by combining database-guided discovery with structure-based design.

48 ackground Digital breast tomosynthesis (DBT)-guided biopsy is increasingly used in practice.

49 ed biopsy (24.8% [191 of 762], P = .54), DBT-guided biopsy helped identify a similar percentage of in

50 M-guided biopsy (27.8% [179 of 643]) and DBT-guided biopsy (24.8% [191 of 762], P = .54), DBT-guided

51 Of the 34 discordant DBT-guided biopsies, 30 were architectural distortions.

52 uided biopsies and 71.1% (542 of 762) of DBT-guided biopsies (P = .03).

53 and 2 years following implementation of DBT-guided biopsy.

54 biopsy and 4.5% (95% CI: 3.2, 6.3) with DBT-guided biopsy (P = .01).

55 mization (RDPSO) algorithm, called diversity-guided Lamarckian RDPSO (DGLRDPSO), is proposed to furth

56 h overall malignancy rate was similar for DM-guided biopsy (27.8% [179 of 643]) and DBT-guided biopsy

57 roups, constituting 89.9% (578 of 643) of DM-guided biopsies and 71.1% (542 of 762) of DBT-guided bio

58 nce rate was 1.4% (95% CI: 1.0, 2.7) with DM-guided biopsy and 4.5% (95% CI: 3.2, 6.3) with DBT-guide

59 he eubacterium Thermus thermophilus, the DNA-guided Argonaute TtAgo defends against transformation by

60 TR circuitry highlights the use of evolution-guided studies to reveal fundamental biological processe

61 to assess the effectiveness of a facilitator-guided, group-based, self-help intervention (Self-Help P

62 Self-Help Plus is an innovative, facilitator-guided, group-based self-help intervention that can be r

63 an subjects (7 female) and applied a feature-guided multivariate source-separation decomposition to d

64 FFR-guided heart rate settings had no adverse effect on LV s

65 hem, 209 patients underwent CABG and 209 FFR-guided PCI.

66 to determine the association between an FFR-guided revascularization strategy and all-cause mortalit

67 l infarction, or stroke between CABG and FFR-guided PCI.

68 ent, site-level, and procedural factors, FFR-guided revascularization was associated with a 43% lower

69 In this phase II study, FFR-guided rate-response programming determined using a repr

70 cerebrovascular events was higher in the FFR-guided PCI versus the CABG group (44.5% versus 31.9%; ha

71 revascularization was more frequent with FFR-guided PCI (24.9% versus 8.2%; hazard ratio, 3.51 [95% C

72 and cerebrovascular events compared with FFR-guided PCI, driven by a higher rate of repeat revascular

73 ntestinal peristalsis disorder and NIR-II FI-guided intestinal obstruction surgery.

74 FLIm-guided Raman imaging could rapidly identify degrees of c

75 On this basis, fluorescence-guided resection of tumor masses was successfully carrie

76 lung cancer, as well as during fluorescence-guided robotic surgery.

77 astatic lesions, and to perform fluorescence-guided surgical tumour resection, in mice.

78 n of the CRM status, back-table fluorescence-guided imaging (FGI) of the fresh surgical resection spe

79 Here we used fMRI-guided transcranial magnetic stimulation (TMS) and simul

80 Contact force-guided radiofrequency ablation is the dominant technique

81 Contact force-guided radiofrequency ablation of persistent atrial fibr

82 t sequence assembly, both de novo and genome-guided, can be used for these sRNA-Seq data, greatly red

83 Warfarin care bundles (e.g. genotype-guided warfarin dosing, patient's self-testing [PST] or

84 outcomes included agreement to the genotype-guided recommendations.

85 CYP2C19 genotype results along with genotype-guided pharmacotherapy recommendations using a rapid tur

86 Image-guided VAB alone did not detect surgically confirmed res

87 bling cancer-selective imaging agents, image-guided surgery provides surgical oncologists and interve

88 tunities for molecular diagnostics and image-guided biomedical applications.

89 MPI), photoacoustic imaging (PAI), and image-guided drug delivery with a tunable drug release capacit

90 Imaging and image-guided procedures play an imperative role in the screeni

91 zation (cTACE) is a guideline-approved image-guided therapy option for liver cancer using the radiopa

92 , focus surgical resection, and enable image-guided biopsy.

93 hesizing Gd-based nanotheranostics for image-guided cancer therapy.

94 nts create important opportunities for image-guided combination therapy.See related article by Ghosh

95 ntial to combine both fluorescence for image-guided surgery (IGS) and photodynamic therapy (PDT) to r

96 oral resolution, and remarkable NIR-II image-guided photothermal therapy.

97 This combination of dual-NIR-II image-guided surgery can be performed under bright light, addi

98 able fluorescence probes might improve image-guided surgery in the clinic.

99 ted the ability of minimally invasive, image-guided vacuum-assisted biopsy (VAB) to reliably diagnose

100 n feasibility trials with percutaneous image-guided tissue sampling for the identification of breast

101 Background Prophylactic image-guided procedures performed by interventional radiologis

102 se to NST and underwent study-specific image-guided VAB before guideline-adherent breast surgery.

103 d help to increase the accuracy of the image-guided biopsy process by providing the information of ti

104 Focused ultrasound is an imaging-guided method for creating therapeutic lesions in deep-b

105 ized molecule-targeted and molecular imaging-guided therapies.

106 nanoplatform, named TCZ-PNPs, for PA-imaging-guided therapy of RA.

107 isualizing metastasis and performing imaging-guided lymph node surgery is challenging.

108 hrombosis remained frequent in spite of IMWG-guided thromboprophylaxis, suggesting that new approache

109 ybrid guided space-time modes that are index-guided in one transverse dimension and localized along t

110 is problem, we developed the Know-GRRF (know-guided regularized random forest) method that enables dy

111 With literature-guided causal inference tools, >300 site-specific signal

112 s advantageous for performing immediate LSCI-guided adjustments in real time.

113 and acute procedure success of different LSI-guided ablation protocols combining higher or lower radi

114 for low-to-medium resolution EM density map-guided structure modeling starting from amino acid seque

115 ucture modeling and atomic-level density map-guided structure refinement.

116 apping and electroanatomical voltage mapping-guided endomyocardial biopsy showed low endocardial volt

117 this approach may lead to a novel, mechanism-guided therapy for AF.

118 Here, we tested two hypotheses: (1) memory-guided predictions about CCD precede control adjustments

119 IP and FEF while macaques performed a memory-guided saccade task.

120 e activity of which is thought to aid memory-guided behavior by forming a mental map of an animal's e

121 ting that the hippocampus coordinates memory-guided eye movements.

122 f environmental layout and (top-down) memory-guided generation of visuospatial imagery and navigation

123 y in the areas that are active during memory-guided direction comparisons, area MT and the prefrontal

124 ntion-predicts the quality of ensuing memory-guided behavior.

125 C, two regions that are important for memory-guided behaviors, in two tasks: one where attention was

126 state of the brain are important for memory-guided navigation and rely on visual inputs.

127 n selectivity, and its utilization in memory-guided perceptual decisions.

128 sual targets and the motor metrics of memory-guided saccades from the spatial locations stored in WM,

129 e valuable information for supporting memory-guided behavior.

130 upcoming events, we hypothesized that memory-guided attention is supported by neural preparation for

131 Together, our results show that memory-guided identity templates proactively impact perception

132 ility to link hippocampal dynamics to memory-guided behaviors has been limited by experiments that la

133 standing of the mechanisms underlying memory-guided adjustments of cognitive control.SIGNIFICANCE STA

134 s with specific miRNA expression using miRNA-guided neuron tags (mAGNET).

135 New model-guided delivery profiles were designed to precisely lead

136 Our results show the value of model-guided design as an approach for generating useful DNA p

137 imple behaviors.SIGNIFICANCE STATEMENT Motor-guided sensation and perception are intertwined, with mo

138 dies have shown that magnetic resonance (MR)-guided low-intensity focused ultrasound (FUS) can revers

139 MRI-guided focused ultrasound (MRgFUS) is a promising non-in

140 MRI-guided radiotherapy is a novel and rapidly evolving tech

141 MRI-guided radiotherapy offers a new tool for the radiation

142 Key challenges to advancing MRI-guided RT include real-time volumetric anatomic imaging,

143 Conclusion Percutaneous CT- and MRI-guided cryoablation of cT1 renal cell carcinoma had simi

144 ased, blood-brain-barrier disrupting and MRI-guided focused ultrasound.

145 This integration, known as MRI-guided RT, has been motivated by the superior soft-tissu

146 Background MRI-guided focused US thalamotomy of ventral intermediate nu

147 lts and who underwent subsequent in-bore MRI-guided biopsy at our university hospital (average time i

148 Performing confirmatory in-bore MRI-guided biopsy following positive transrectal US-guided b

149 An overall disease upgrade by in-bore MRI-guided biopsy occurred in 40% (16 of 40) of cases (61.5%

150 f 71) were visible on MR images (in-bore MRI-guided biopsy results were positive in 52.6% [30 of 57])

151 In-bore MRI-guided biopsy upgraded 60% (18 of 30) and downgraded 3.3

152 cancer detection rate when using in-bore MRI-guided biopsy was 65% (26 of 40).

153 terial-enhanced) and transrectal in-bore MRI-guided biopsy were performed.

154 cases with positive results from in-bore MRI-guided biopsy).

155 the current and future applications for MRI-guided radiotherapy with respect to metastatic and prima

156 Furthermore, MRI-guided linear accelerator systems, allowing use of MRI d

157 overlap with transcriptional profiles of MRI-guided human FSHD muscle biopsies.

158 erging innovations in offline and online MRI-guided RT, exciting opportunities they offer for advanci

159 eatment of recurrent depression, and the MRI-guided method of coil targeting is not better than the s

160 fforts are underway to develop real-time MRI-guided intrafraction adaptive RT of tumors affected by m

161 ng a low-frequency clinical transcranial MRI-guided focused ultrasound (TcMRgFUS) device and evaluate

162 NIR-guided SLN mapping may improve staging and outcomes thro

163 receiving optical coherence tomography (OCT)-guided intravitreal injections.

164 We describe OCT-guided localization and photocoagulation of these invisi

165 ent strategies, with a trend in favor of OCT-guided vs BCVA loss guided retreatment.

166 Sniffing allows animals to make odor-guided decisions within ~200 ms, but animals routinely e

167 The OLA-guided therapy group had pre-ART peripheral blood mononu

168 OPEX-guided exploration of Escherichia coli's populations exp

169 particles, the crystallographic orientation-guided redox reaction governs the charge distribution in

170 Outcome-guided behavior requires knowledge about the current val

171 , but a causal role for human OFC in outcome-guided behavior has not been established.

172 siloxane) matrix, the rheological-parameters-guided DLS can print structures seven times tougher than

173 many cooperative groups in the study of PET-guided therapy.

174 609 DLBCL patients participating in the PET-Guided Therapy of Aggressive Non-Hodgkin Lymphomas trial

175 izumab using pharmacokinetic/pharmacodynamic-guided dosing, requiring a median of 11 doses of eculizu

176 Pharmacokinetics-guided lead optimization resulted in the derivative QD39

177 This gene-based, PheWAS-guided approach can accelerate the discovery of clinical

178 Physician-guided discontinuation of DAPT appears to be safe, irres

179 of DAPT cessations were defined as physician-guided DAPT discontinuation, brief interruption (<14 day

180 Physiology-guided PCI has shown to improve clinical outcomes in mul

181 E3 ligase Su(var)2-10 are required for piRNA-guided deposition of repressive chromatin marks and tran

182 of glioma-bearing mice with proapoptotic PL3-guided NWs improved the survival of the mice, whereas tr

183 MYD88 and CXCR4 can be used for a precision-guided treatment approach to WM.

184 practice as in clinical trials, PA pressure-guided therapy for HF was associated with lower PA press

185 ssess the efficacy and safety of PA pressure-guided therapy in routine clinical practice with special

186 Outcome data from procalcitonin-guided therapy trials have shown similar mortality, but

187 Neither procalcitonin-guided antibiotic treatment (0.91 [0.82-1.01]; p = 0.09)

188 r antibiotic duration, neither procalcitonin-guided therapy (0.93 [0.84-1.03]; p = 0.15) nor fixed-du

189 s of mortality associated with procalcitonin-guided therapy did not reach the trial sequential monito

190 Using a quantitative proteomics-guided approach, we then estimated the fractional contri

191 to determine the success rate of (68)Ga-PSMA-guided bone biopsies for molecular diagnostics in mPC pa

192 ate (tumor percentage >= 30%) of (68)Ga-PSMA-guided bone biopsies.

193 This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph n

194 we use airborne light detection and ranging-guided hyperspectral imagery to map foliar nutrient (i.e

195 the inclusion of moxifloxacin in resistance-guided strategies and extend the evidence for 2.5 g azit

196 ss this issue, rats were trained on a reward-guided decision-making task; reward value was manipulate

197 n novel visuospatial discriminations (reward-guided learning).

198 n the theta frequency (4-8 Hz) during reward-guided behavior, but it is unclear whether this oscillat

199 the OFC are critically important for reward-guided learning and that they are driven by theta oscill

200 e found that deficits specifically in reward-guided choice behavior on the probabilistic reversal lea

201 l and thalamocortical interactions in reward-guided learning in the normal brain and identify brain s

202 rats performed the previously learned reward-guided decision-making task while we recorded from singl

203 tions (learning-to-learn) and to make reward-guided decisions.SIGNIFICANCE STATEMENT Frontal neural n

204 nipulating haemodynamic signatures of reward-guided learning observed in human fMRI studies by using

205 and the temporal lobes contribute to reward-guided learning in mammals.

206 ble lithium-sulfur (Li-S) full cell with rGO-guided planar Li layers as the anode exhibits stable cyc

207 o-G base editors (CGBE1), consists of an RNA-guided Cas9 nickase, an Escherichia coli-derived uracil

208 R-Cas9 from Streptococcus pyogenes is an RNA-guided DNA endonuclease, which has become the most popul

209 Cas12a (Cpf1) is an RNA-guided endonuclease in the bacterial type V-A CRISPR-Cas

210 The CRISPR-Cas12a RNA-guided complexes have tremendous potential for nucleic a

211 Cas12a RNA-guided endonucleases are promising tools for multiplexed

212 CRISPR RNA-guided endonucleases (RGEs) cut or direct activities to

213 IF9) in complex with the type I-F CRISPR RNA-guided surveillance complex (Csy).

214 Bacterial CRISPR-Cas systems employ RNA-guided nucleases to destroy phage (viral) DNA.

215 ms lacking Cas3 have been repurposed for RNA-guided transposition by bacterial Tn7-like transposons(6

216 To provide immunity, RNA-guided protein surveillance complexes recognize foreign

217 Some of these variants are involved in RNA-guided transposition, whereas others are predicted to pe

218 ns use a single RuvC active site to make RNA-guided breaks in double-stranded DNA substrates, an acti

219 Deployment of RNA-guided DNA endonuclease CRISPR-Cas technology has led to

220 d (CRISPR/Cas) system as a programmable, RNA-guided endonuclease has revolutionized the utilization o

221 I-F CRISPR-Cas system for programmable, RNA-guided transposition.

222 Cas9 is a prokaryotic RNA-guided DNA endonuclease that binds substrates tightly in

223 and archaeal CRISPR-Cas systems provide RNA-guided immunity against genetic invaders such as bacteri

224 Powerful and simple, RNA-guided CRISPR/Cas9 technology is a versatile genome edit

225 Using the RNA-guided nuclease Cas9, we induced two DNA double-strand b

226 In this study, we used the RNA-guided nuclease CRISPR-Cas9 (clustered regularly-intersp

227 CRISPR proteins (Acrs) to inactivate the RNA-guided nucleases that enforce CRISPR-Cas adaptive immuni

228 bility, accuracy and efficacy of a new robot-guided system for semi-automated, minimally invasive, pe

229 This work establishes Rosetta-guided design and incremental aaRS improvement as a viab

230 entary luciferase was identified via Rosetta-guided enzyme design.

231 Scaffold-guided formation of neuronal-like networks, especially u

232 as achieved using a single guide RNA (sgRNA)-guided and catalytically impaired Campylobacter jejuni C

233 Here, we report a highly efficient in silico-guided approach that led to the discovery of novel allos

234 tions that could significantly advance sonar-guided systems.

235 the remarkable differences between the stage-guided and the hierarchical strategies.

236 STAR-guided AFD ablation through sequential mapping with a mu

237 2 out of 27 (81.5%) patients undergoing STAR-guided ablation were free from AF/atrial tachycardia off

238 ion, leaving 27 patients that underwent STAR-guided AFD ablation.

239 Structure-guided functional assays in Drosophila S2 cells confirme

240 Structure-guided mutagenesis and docking studies demonstrate the i

241 Structure-guided phylogeny of MCP suggests that Yaravirus groups t

242 We characterized 100 structure-guided spike designs and identified 26 individual substi

243 This study provides a structure-guided definition of the PIRs and a molecular framework

244 , we describe the application of a structure-guided fragment-based drug discovery approach to the des

245 e protease activity, we employed a structure-guided mutagenesis approach and identified residues that

246 ent library screening, followed by structure-guided chemical elaboration of hits, led to the rapid de

247 e 2-position that was optimized by structure-guided compound design.

248 ilizes a high FRET value, which by structure-guided mutagenesis corresponds to a closed conformation

249 Here, by structure-guided truncations, confocal microscopy, and cryoelectro

250 By using CaMKII structure-guided inhibitor design, we generated four families of b

251 Carefully designed structure-guided or strategically selected disease-associated muta

252 X-ray crystallography enabled structure-guided design, leading to the identification of preferre

253 s, CPTX represents a prototype for structure-guided biologics that can efficiently repair or remodel

254 lay out an important framework for structure-guided drug discovery targeting MCTs.

255 As a prerequisite for structure-guided investigation of enzymatic activity, we determine

256 d key factors important for future structure-guided optimization delivering IMP-105 (43), a compound

257 Functional evaluation of KAT1 structure-guided mutants at the sensor-pore interfaces suggests a

258 Using cryo-electron microscopy, structure-guided mutagenesis, and cell-based assays, we reveal the

259 ble impact on future ligand and/or structure-guided chemical optimizations, as well as opportunities

260 have been mitigated through recent structure-guided approaches and include trimer-stabilizing mutatio

261 presents an example of successful, structure-guided development of low molecular weight inhibitors sp

262 iV interaction, demonstrating that structure-guided alanine-scanning and computational modeling can s

263 The structure-guided optimization of the pyridone hit 3 using this bio

264 otency to nanomolar levels through structure-guided analogue design.

265 Herein, we used structure-guided alanine-scanning mutagenesis to map the functiona

266 Herein, we have used structure-guided computational screening and optimization to devel

267 Using structure-guided sequence analysis we uncover previously uncharact

268 esulted in a greater need for susceptibility-guided treatment.

269 e key role of GC in the execution of a taste-guided, reward-directed decision-making task.

270 iceal source) were randomly allocated to TEG-guided transfusion strategy (TEG group; n = 49) or stand

271 erforms conformational sampling and template-guided energy refinement to produce a variety of possibl

272 nt for tuberculosis was not superior to test-guided treatment in reducing the rate of death or invasi

273 ell receptor (TCR) deep sequencing, tetramer-guided naive CD4 T-cell precursor enumeration, and whole

274 We suggest that a theory-guided search across model systems for biological mechan

275 via recognition by TOM20, followed by TIMM50-guided translocation of IRAK2 into mitochondria inner me

276 We report a method called 'tomography-guided 3D reconstruction of subcellular structures' (TYG

277 Computed tomography-guided fine-needle aspiration for Gram stain and culture

278 e transition to digital breast tomosynthesis-guided biopsy, more architectural distortions were biops

279 t exciton displacement, appropriate topology-guided assembly is required to fully realize the true po

280 dentified and characterized by transcriptome-guided RT-PCRs and Sanger sequencing.

281 Ultrasound-guided percutaneous drainage revealed "anchovy sauce" pu

282 study, low- intensity collimated ultrasound-guided anatomic mapping and robotic ablation allows PV i

283 NSCLC who underwent endobronchial ultrasound-guided staging from a single center were included.

284 s of treatment such as endoscopic ultrasound-guided glue-coiling combination therapy and the emergenc

285 o develop a strategy to follow in ultrasound-guided treatments of varices in the lower limbs, as well

286 patients who underwent real-time ultrasound-guided percutaneous biopsies of space-occupying liver le

287 n are advised to have transrectal ultrasound-guided biopsy in an attempt to locate a cancer.

288 Here we used ultrasound-guided fine needle aspiration to serially sample the dra

289 nce-dependent generalization and uncertainty-guided exploration as a Gaussian Process regression with

290 gate whether predispositions for uncertainty-guided information seeking relate to individual differen

291 hanisms that could underlie such uncertainty-guided control have been largely unknown.

292 of inflammatory-type material obtained by US-guided fine-needle biopsy of the pleural lesion were pos

293 On the basis of the imaging findings, US-guided fine-needle aspiration cytology was performed to

294 If US-guided tissue sampling was performed, results were obtai

295 positive results detected by transrectal US-guided biopsy (from all 40 patients), 80% (57 of 71) wer

296 ded biopsy following positive transrectal US-guided biopsy resulted in a high disease-upgrade inciden

297 who had previously undergone transrectal US-guided biopsy with positive results and who underwent su

298 onto an interactive 3D mouse model for user-guided exploration.

299 These results support the notion that value-guided learning and generalization recruit cognitive-map

300 able coding scheme simplifies readout for WM-guided behaviour, whereas the low-dimensional dynamic co