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2 r recruitment and binding of ALG-2 and ALG-2-interacting protein X (ALIX) to the damaged membrane.
4 e Bro1 domain-containing protein ALIX (Alg-2-interacting protein X) to recruit and activate ESCRT-III
7 CSC, the tumor suppressor disabled homolog 2-interacting protein (DAB2IP) is silenced by EZH2-mediate
10 between the Cu-chelating group and the Abeta-interacting fragments further improves the in vivo Abeta
11 uses a bifunctional chelator with two Abeta-interacting fragments that dramatically improves the Abe
13 Consequently, antibodies targeting the ACE2-interacting surface (ACE2IS) located in the receptor-bin
14 ect interaction within a newly identified AR-interacting motif (AIM) in the ETS domain, independent o
15 characterized a family of nuclear Argonaute-interacting proteins (ENRIs) that control the strength a
16 terminus of the Serum Resistance Associated-interacting domain (SRA-ID), but not the membrane-addres
17 binding proteins exploit a well-defined ATG8-interacting motif (AIM, or LC3-interacting region [LIR])
18 and Rtn2 interact with Atg8a using four Atg8-interacting motifs (AIMs) located at the C-terminus, cyt
20 , such as the cell-cycle regulator cyclin B1-interacting protein 1 (Ccnb1ip1) and thymidine kinase (T
21 t muscle, there are increased levels of BAG3-interacting proteins, such as p62, heat shock protein B8
22 can be mimicked by loss of function of BAK1-INTERACTING RECEPTOR-LIKE KINASE1 (BIR1), a known negati
23 t complexes with the LRR ectodomains of BAK1-INTERACTING RECEPTOR-LIKE KINASE3 (BIR3) receptor pseudo
24 ein colocalized and associated with the BAK1-INTERACTING RECEPTOR-LIKE KINASES BIR2 and BIR3, which a
25 immunoprecipitation studies identified BCALM-interacting proteins in B cells, including phospholipase
26 ed proteomic analysis to identify other BCAP-interacting proteins in macrophages and found that BCAP
27 e are initially sequestered in a branchpoint-interacting stem-loop (BSL)(8), but whether the human U2
28 modelling of the BSL and displacement of BSL-interacting proteins must occur to allow formation of th
29 aments, whereas deletion of Bud4 or its Bud3-interacting domain destabilizes the transitional hourgla
31 urin B-Like (CBL) calcium sensors and 26 CBL-Interacting Protein Kinases (CIPKs) of Arabidopsis (Arab
33 evaluated the contributions of the two CCR1-interacting regions of the cognate chemokine ligand CCL7
36 atory auxiliary subunits called K(+) channel-interacting proteins (KChIPs) modulate Kv4 expression an
37 the Kv4 subfamily associate with Kv channel-interacting proteins (KChIPs), which leads to enhanced s
41 altering the structure of a putative client-interacting loop and 2) disrupt chaperone-client interac
43 comprehensively identify additional cohesin-interacting proteins, we used gene editing to introduce
44 hese results identify USP13 as a new cohesin-interacting protein that regulates the ubiquitination of
46 ated that cryptochrome 2 (Cry2)/cryptochrome-interacting beta helix-loop-helix (CIB), a blue light-ac
48 sitioned to the fork DNA while its CIP (Ctf4-interacting peptide)-binding helical domains remain avai
49 It has structural homology to a cytoskeleton-interacting protein and accumulates at the site of ookin
50 d on the high similarity of ATLs and the DNA-interacting domain of AGTs, our results provide importan
51 and activity of RLIM (RING finger LIM-domain-interacting protein, encoded by the RNF12 gene), a novel
52 ns) transfer proteins PYK2 N-terminal domain-interacting receptor 2 (Nir2) and Nir3 specifically asso
53 ACTING F-BOX KELCH 1 (CFK1), as a novel DRM2-interacting partner and targets DRM2 for degradation via
55 ecycling protein (EARP) complex and the EARP-interacting-protein EIPR-1 as proteins important for con
56 e results demonstrate that sSORLA is an EGFR-interacting protein that activates EGFR/ERK/Fos signalin
57 and upon Arp2/3 inhibition forms extended ER-interacting invaginations, indicating that sterol transf
59 steric binding proteins such as Nedd4 family-interacting protein (NDFIP1), engineered ubiquitin varia
61 scaffold Ragulator, and the FLCN:FNIP2 (FLCN-interacting protein 2) GTPase activating protein (GAP) c
63 s-1 (FLII) and leucine-rich-repeat-(in FLII)-interacting-protein-1 as a regulatory complex for UCP1 t
65 xecuted by a complex of Frequency (FRQ), FRQ-interacting RNA helicase (FRH), and casein kinase I (CKI
67 like transcription modulator (SLTM) as a GLI-interacting protein that context-dependently regulates G
69 ay to overcome this challenge, based on GPCR-interacting biosensors that are disconnected from endoge
70 ULATING FACTOR 4 (GRF4) and its cofactor GRF-INTERACTING FACTOR 1 (GIF1) substantially increases the
71 using the GLI1-regulated gene HHIP (Hedgehog-interacting protein) as a model, we demonstrate that GLI
72 roteins are required to recruit WRN helicase-interacting protein 1 (WRNIP1), RAD51 recombinase (RAD51
73 transferase (OGT) for Drosophila homeodomain-interacting protein kinase (Hipk)-induced growth abnorma
74 od, and we demonstrate here that homeodomain-interacting protein kinase 4 (HIPK4) is essential for sp
77 e ubiquitin ligase CHIP (C terminus of HSC70-interacting protein) promoted SIRT6 stability, but CHIP
79 p70-associated E3 ligase c-terminus of Hsp70-interacting protein (CHIP) and subsequent degradation in
80 shock protein 70 (Hsp70):c-terminus of Hsp70-interacting protein (CHIP) complex facilitates the ubiqu
82 he Caenorhabditis elegans protein huntingtin-interacting protein-related 1 (HIPR-1) as a host factor
84 and VOZ2 transcription factors (TFs) as IBI1-interacting partners, which are transcriptionally induce
86 etal uptake is regulated, we identified IRT1-interacting proteins in Arabidopsis roots by mass spectr
87 contains motifs exclusively conserved in KBP-interacting kinesins, suggesting a basis for kinesin sel
90 increased phosphorylation of the PI 3-kinase-interacting Tyr-751 residue of PDGFRbeta, thus activatin
91 fic, brain-penetrant inhibitor of MAP kinase-interacting kinases resets the translation of mRNA and r
92 ting of the mitogen-activated protein kinase-interacting kinase (MNK1/2) and its phosphorylation targ
93 ped with the KIX recognition region, key KIX-interacting E2A-AD1 residues were exposed, suggesting th
96 ent, and mass spectrometry to identify KPNA7-interacting proteins in human induced pluripotent stem c
98 in, encoded by the RNF12 gene), a novel LANA-interacting protein identified in that protein screen.
102 w that pejvakin-LC3B binding involves an LC3-interacting region within the predicted chaperone domain
103 -defined ATG8-interacting motif (AIM, or LC3-interacting region [LIR]) that contacts a hydrophobic pa
104 nds on specific interactions between the LC3-interacting region (LIR) docking site (LDS) in ATG8s and
110 own and new lysosomal membrane and lysosomal-interacting proteins in human iPSC-derived neurons.
112 omplex 1 (mTORC1)-dependent increase in MAPK-interacting kinase 1 (MNK1) and eukaryotic translation i
114 RA is common to both complexes, its membrane-interacting loops are critical for complex II, but have
115 tide research has produced numerous membrane-interacting peptides that inhibit diverse enveloped viru
117 r is a dimer of dimers, wherein the membrane-interacting BAR surfaces are sequestered and the PX lipi
118 ant cav-1 construct, comprising the membrane-interacting domains and a C-terminal palmitoyl tail.
122 dditives where the 3D arrangement of mineral-interacting functions can be designed at will, promising
123 nnatural amino acid and subsequently mineral-interacting functions via selective-pressure incorporati
129 Here, we analyse the role of the TRAF2-/NCK-interacting kinase (TNIK), a signaling molecule downstre
131 e a peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1)-dependent mechanism that regulates
135 ect of different sampling approaches for non-interacting pairs on the training and the performance of
136 erimentally demonstrate an inadequacy of non-interacting Landauer theory as well as the conventional
138 herent in the negative sample selection (non-interacting proteins), we propose a clustering-based app
139 i systems can be predicted using simple 'non-interacting' magic number tables, without the need for l
143 inase TaSnRK1alpha is identified as an Osp24-interacting protein and shows to be important for FHB re
147 efficient editing activity, we graft the PAM-interacting domain of SmacCas9 to its well-established o
151 r other proline-serine-threonine phosphatase-interacting protein 1-associated inflammatory disorders
154 ERBB4, as well as the intact phosphotyrosine-interacting SH2 domain of VAV3, are necessary for this i
156 SSINAZOLE-RESISTANT 1 (BZR1) and PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) repress AGO10 transcription
158 lated in pp7l-1 were enriched in PHYTOCHROME-INTERACTING FACTOR (PIF)-binding motifs and the transcri
159 nes through direct regulation of PHYTOCHROME-INTERACTING FACTOR (PIF) transcription factor abundance
161 temperature sensor, and the phyB-PHYTOCHROME-INTERACTING FACTOR 4 (PIF4)-auxin module is only one thr
164 abundance of PIF4 and PIF5, two phytochrome-interacting bHLH-family transcription factors that play
165 NG FACTORs (CBFs), interact with PHYTOCHROME-INTERACTING FACTOR 3 (PIF3) under cold stress, thus atte
166 can phosphorylate Fab1 proximal to its PI3P-interacting FYVE domain, which causes Fab1 to shift to s
169 ot only identified an additional set of PI5P-interacting proteins but also revealed the strong PI5P-b
170 -throughput and systematic screening of PI5P-interacting proteins with PI5P-tagged fluorescent liposo
171 InterPro domain analysis indicated that PI5P-interacting proteins are enriched in the P-loop containi
176 We show that TART-A produces abundant Piwi-interacting small RNAs (piRNAs), some of which are antis
177 hylation, repressive histone marks, and PIWI-interacting RNA (piRNA) are essential for the control of
180 NAs), especially microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs), play key roles in many biolog
182 otein MIWI2 (PIWIL4) and its associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation of tr
183 e PIWI protein MIWI2 and its associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation of yo
184 tivity is repressed in animal gonads by PIWI-interacting RNAs (piRNAs) produced by piRNA clusters.
185 limited by a class of small RNAs called PIWI-interacting RNAs (piRNAs) produced by dedicated genomic
186 Somatic and germline cells both express piwi-interacting RNAs in jellyfish revealing a conserved cnid
187 tive strategy employs small RNA guides, Piwi-interacting RNAs (piRNAs) to identify targets of transcr
196 In insects, TEs are controlled by the Piwi-interacting small interfering RNA (piRNA) pathway in gon
199 of two Polycomb repressive complex 2 (PRC2)-interacting proteins, Pcl and Scm, initiate silencing du
200 t with their target gene promoters (promoter-interacting eQTLs, pieQTLs) in five common immune cell t
203 oth ubiquitin-interacting UBA and proteasome-interacting UBL domains, the UBL domain is atypical, as
206 ion domain mapping on this and other protein-interacting pairs, including CRAF-MEK1, RIT1-RGL3, and p
209 e, we dissected the distinct actions of Rab3-interacting molecule and Munc13-1 from both ultrastructu
210 studies reveal previously unrecognized RAMP-interacting GPCRs, many of which expand beyond Class B G
212 lar mechanism, we searched for EBP1- and RBR-interacting proteins by affinity purification and mass s
218 rferon regulatory factor 3 (IRF-3), receptor-interacting protein 1, IFNbeta-1, and nucleotide-binding
219 poptosis (PANoptosis) by activating receptor-interacting Ser/Thr kinase 3 (RIPK3), caspase-8, and the
220 e that absent in melanoma 2 (AIM2), receptor-interacting serine/ threonine protein kinase 3 (RIPK3),
221 in the incidence of caspase-8- and receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-me
222 as necroptosis that is mediated by receptor-interacting protein kinase 1 (RIPK1), RIPK3 and mixed li
223 des causing necroptotic cell death, receptor-interacting protein kinase 3 (RIPK3) has an alternate fu
225 een identified the aryl hydrocarbon receptor-interacting protein (AIP), a co-chaperone protein, as re
227 the necroptotic pathway, including receptor-interacting protein kinase-3 (RIPK3), mixed lineage kina
228 ts due to mu1 knockdown potentiates receptor-interacting protein 3 (RIP3)-dependent cell death.IMPORT
229 neuronal necroptosis via recruiting receptor-interacting protein kinase 1 (RIPK1) to its C terminus (
230 P was p53 independent, and required receptor-interacting protein kinase 1 (RIP1) and c-Jun N-terminal
231 s, one of which is related to RHIM [receptor-interacting protein (RIP) homotypic interaction motif],
232 and immunohistochemistry for RIPK1 (receptor-interacting protein kinase-1), MLKL (mixed lineage kinas
233 L necroptotic machinery lies RIPK1 (receptor-interacting serine/threonine-protein kinase 1), which ac
234 e atherogenic plaque undergo RIPK3 (receptor-interacting serine/threonine-protein kinase 3)-MLKL (mix
235 tonitis, we show in this study that receptor-interacting protein kinase (RIPK) 3 impacts pyrin inflam
236 sented by necroptosis, in which the receptor-interacting protein kinase-3 and its substrate mixed-lin
239 more recently, also in relation to receptor-interacting protein kinase-driven necroptosis, whereas u
240 is a lytic RNA virus that triggers receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-me
241 by host regulatory mechanisms, including RLR-interacting proteins, post-translational modifications a
242 together with the RNA polymerase II (RNAPII)-interacting protein RECQ5, promotes SUMO2-PCNA conjugati
247 lysis, which identified several known SecYEG-interacting proteins, verified the interaction of SecYEG
249 ating the findings, we identified three self-interacting regions and two types of self-association, t
251 scovered that the repressor domain SID (SIN3-interacting domain) derived from the MXD1 protein is hig
252 ransporter function and is utilized by slc13-interacting proteins in the regulation of metabolite tra
253 Our previous data showed that the SnRK2-interacting Calcium Sensor (SCS) inhibits SnRK2 activity
259 ectly binds to TRIF, we identified the STING-interacting domain of TRIF and generated STING-nonintera
260 rough regeneration, we identify the Striatin-interacting phosphatase and kinase (STRIPAK) complex as
261 riatins) that are components of the Striatin-interacting phosphatase and kinase (STRIPAK) complex.
262 ed that Slik is a new member of the striatin-interacting phosphatase and kinase complex (STRIPAK).
263 on of the endoplasmic reticulum (ER) stromal-interacting molecule (STIM) Ca(2+) sensor proteins and t
264 ither a nucleophilic residue nor a substrate-interacting residue, based on the LC-MS/MS data and avai
265 peptide substrates showed that the substrate-interacting residues and the lid structure that folds ov
267 l ubiquitin-like modification)/polySIM (SUMO-interacting motif) condensates, analogous to PML bodies,
269 r 34 transcription factors (TFs) and 24 Swi1-interacting proteins can undergo transcriptional modific
270 inhibitory factor 1 (IF1) is an ATP synthase-interacting protein that suppresses the hydrolysis activ
273 KSHV lytic reactivation, as a novel HIV Tat-interacting lncRNA that potentially mediates HIV-KSHV in
276 transcriptional up-regulation of thioredoxin-interacting protein (TXNIP), a gene that negatively regu
277 gh glucose-induced expression of thioredoxin-interacting protein (TXNIP), an exquisitely glucose-indu
278 ng S and G(2) phases and switches the TopBP1-interacting partner from treslin to E2F1, which results
281 cues FIV mutants lacking a functional TSG101-interacting motif, independently of the entire p2 region
282 urface, that ADAM10 is the principal Tspan15-interacting protein, that endogenous Tspan15 expression
283 vector, we identified and validated six TSWV-interacting proteins from Frankliniella occidentalis fir
284 elucidate gene expression profiles of tumor-interacting monocytes and macrophages as well as blood-d
285 ngiogenic treatments, which target the tumor-interacting and tumor-adjacent cells, have overcome some
286 igands, we thoroughly characterize their TWJ-interacting properties in vitro and demonstrate their ca
288 ntrolled by polyglutamine-adjacent ubiquitin-interacting motifs (UIMs) that enhance aggregation and t
291 In cells lacking OSBP, but not other VAP-interacting cholesterol carriers, the recruitment of mTO
294 a photocrosslinker to covalently link virus-interacting proteins in living cells on UV exposure at d
296 the identification of VINR, a Drosophila VSR-interacting long non-coding (lnc) RNA that activates non
297 ott-Aldrich Syndrome protein (WASP) and WASP-interacting-protein (WIP) regulate T cell antigen recept
298 atio is numerically consistent with a weakly-interacting Fermion system for the near-nodal states.
300 tification of a WD40 protein, XIW1 (for XPO1-interacting WD40 protein 1), which positively regulates