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1  clinically approved PSs porfimer sodium and 5-aminolevulinic acid.
2 entachlorbiphenyl, an inducer of CYP1A2, and 5-aminolevulinic acid.
3 und heme b when expressed in the presence of 5-aminolevulinic acid.
4 roides 2.4.1 which catalyze the formation of 5-aminolevulinic acid.
5 S-catalyzed condensation of two molecules of 5-aminolevulinic acid.
6 he peptide-based photodynamic therapy agent, 5-aminolevulinic acid.
7  fluorinated analog of 5-ALA, i.e., 3-fluoro-5-aminolevulinic acid (3F-5-ALA).
8 scale production of the FDA-approved prodrug 5-aminolevulinic acid (5-ALA) and the late-stage functio
9      Cells were incubated with PpIX pro-drug 5-aminolevulinic acid (5-ALA) at 0, 1, 2, 3, and 4 mM fo
10                        All patients received 5-aminolevulinic acid (5-ALA) fluorescence guidance surg
11 uperiority of intraoperative MRI (iMRI) over 5-aminolevulinic acid (5-ALA) for achieving complete res
12                  In 2017, the FDA authorized 5-aminolevulinic acid (5-ALA) for intraoperative optical
13            Fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA) is now a widely-used modal
14 X (PpIX), which is endogenously derived from 5-aminolevulinic acid (5-ALA) or its derivatives, is a p
15                                      A novel 5-aminolevulinic acid (5-ALA) prodrug was custom-designe
16                   Systemic administration of 5-aminolevulinic acid (5-ALA) results in accumulation of
17                                              5-aminolevulinic acid (5-ALA) was injected at a dose of
18 pathway, and cancer cells accumulate it when 5-aminolevulinic acid (5-ALA), a precursor, is administe
19 sed fluorophore in glioma-resection surgery, 5-aminolevulinic acid (5-ALA), is thought to cause the s
20 microneedles for improved dermal delivery of 5-aminolevulinic acid (5-ALA), which naturally gets conv
21 pical, oral, or parenteral administration of 5-aminolevulinic acid, a precursor for heme biosynthesis
22 tor deferoxamine and the porphyrin precursor 5-aminolevulinic acid (ALA) (mimicking intracellular pro
23                                              5-aminolevulinic acid (ALA) and carnosine have important
24                         In mice treated with 5-aminolevulinic acid (ALA) and polyhalogenated aromatic
25 , constitutively elevated plasma and urinary 5-aminolevulinic acid (ALA) and porphobilinogen (PBG), p
26 HMB-synthase activities and elevated urinary 5-aminolevulinic acid (ALA) and porphobilinogen (PBG), t
27 ation of the neurotoxic porphyrin precursors 5-aminolevulinic acid (ALA) and porphobilinogen (PBG), w
28 tudy, we investigated whether the amino acid 5-aminolevulinic acid (ALA) could sensitize glioma stem
29                   The tetrapyrrole precursor 5-aminolevulinic acid (ALA) inhibited Lhcb expression in
30                             The synthesis of 5-aminolevulinic acid (ALA) is a key regulatory step for
31                                              5-aminolevulinic acid (ALA) is a precursor in the biosyn
32              Photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA) is based upon the intracellu
33 bacteria, the heme and chlorophyll precursor 5-aminolevulinic acid (ALA) is formed from glutamate in
34      Photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) is increasingly employed for
35                                   In plants, 5-aminolevulinic acid (ALA) is the common precursor of t
36                                              5-Aminolevulinic acid (ALA) is the first committed subst
37                                              5-Aminolevulinic acid (ALA) is the first committed unive
38                             The synthesis of 5-aminolevulinic acid (ALA) is the rate-limiting step fo
39                                 Synthesis of 5-aminolevulinic acid (ALA) is the rate-limiting step in
40                                              5-Aminolevulinic acid (ALA) is the universal precursor o
41 ranscripts for the two committed enzymes for 5-aminolevulinic acid (ALA) synthesis despite the marked
42                                  By grafting 5-aminolevulinic acid (ALA) to a Hf(12) -based nanoscale
43  asymmetric condensation of two molecules of 5-aminolevulinic acid (ALA) to form porphobilinogen.
44 r increased ability to convert the precursor 5-aminolevulinic acid (ALA) to PPIX appeared to reinforc
45 talyzes the condensation of two molecules of 5-aminolevulinic acid (ALA), an essential step in tetrap
46 The common precursor to all tetrapyrroles is 5-aminolevulinic acid (ALA), and in Rhodobacter sphaeroi
47 ytes can be potently stimulated by exogenous 5-aminolevulinic acid (ALA), resulting in accumulation o
48           Metabolomic analysis revealed that 5-aminolevulinic acid (ALA), the first heme precursor, i
49 es an FDA-approved human precursor molecule, 5-aminolevulinic acid (ALA), to stimulate a unique delay
50 ation of porphyrin precursors, in particular 5-aminolevulinic acid (ALA), which is thought to be the
51  mice in a 129S6/SvEvTac background were fed 5-aminolevulinic acid (ALA), which results in hepatic UR
52 Here, we investigated the in vivo effects of 5-aminolevulinic acid (ALA)-mediated SDT on early-stage
53  asymmetric condensation of two molecules of 5-aminolevulinic acid (ALA).
54 n IX (PPIX), can be enhanced in the cells by 5-aminolevulinic acid (ALA).
55 s been shown to have higher specificity than 5-aminolevulinic acid and can possibly play a complement
56                 Fluorescence cystoscopy with 5-aminolevulinic acid and hexaminolevulinate has been sh
57 ehydratase deficient porphyria) or increased 5-aminolevulinic acid and porphobilinogen (in patients w
58 is caused by restriction on the formation of 5-aminolevulinic acid and protochlorophyllide.
59  mutant has a reduced capacity to synthesize 5-aminolevulinic acid and reduced CHLM activity compared
60 quantitative measurement of porphobilinogen, 5-aminolevulinic acid, and total porphyrin levels.
61 HL27, and contributes to feedback-control of 5-aminolevulinic acid biosynthesis, the rate-limiting st
62        Little is known about the movement of 5-aminolevulinic acid (delta-aminolevulinic acid; ALA) b
63 oroplasts by feeding these chloroplasts with 5-aminolevulinic acid, determined the relative levels of
64                    Our results indicate that 5-aminolevulinic acid feeding stimulates Mg-chelatase ac
65  strongly accumulates in mutant leaves after 5-aminolevulinic acid feeding.
66 re classified according to micro-cystoscopic 5-aminolevulinic acid fluorescence diagnosis, and specim
67 application of the photosensitizer precursor 5-aminolevulinic acid has therapeutic implications for t
68 tial use of the combination of tellurite and 5-aminolevulinic acid in antimicrobial therapy.
69 s relies on measurement of increased urinary 5-aminolevulinic acid (in patients with aminolevulinic a
70 enzoporphyrin derivative monoacid ring A and 5-aminolevulinic acid-induced protoporphyrin IX, were st
71 ll as show the direct in vitro conversion of 5-aminolevulinic acid into cobyrinic acid using a mixtur
72                                        Hexyl-5-aminolevulinic acid is an ester form of 5-aminolevulin
73 creased synthesis of glutamate semialdehyde, 5-aminolevulinic acid, magnesium-porphyrins, and chlorop
74  the carrier's physiological ligand, whereas 5-aminolevulinic acid makes far fewer interactions compa
75 ht photodynamic therapy using topical methyl 5-aminolevulinic acid (MAL) for actinic keratoses (AKs)
76        With this model, we demonstrated that 5-aminolevulinic acid-mediated sonodynamic therapy (ALA-
77 ed by favoring low-activity oligomers, while 5-aminolevulinic acid, Mg(2+), or K(+) stabilized high-a
78 droxybenzoic acid (3,4-AHBA), and a cyclized 5-aminolevulinic acid moiety, 2-amino-3-hydroxycyclopent
79 alloenzyme catalyzes the condensation of two 5-aminolevulinic acid molecules to form the tetrapyrrole
80 ethylnicotinamide, 3-hydroxyisovaleric acid, 5-aminolevulinic acid, N-acetylglutamine and methanol-wh
81 kinin contents and de-represses synthesis of 5-aminolevulinic acid of tetrapyrrole metabolism in dark
82 ment of tumor-specific fluorophores, such as 5-aminolevulinic acid, real-time microscopic visualizati
83 the initiating enzyme for heme biosynthesis, 5-aminolevulinic acid synthase (ALAS), by promoting cofa
84                                              5-Aminolevulinic acid synthase (ALAS-1) is the first rat
85 and enzymatic assays indicate that erythroid 5-aminolevulinic acid synthase (Alas2) is decreased in h
86 cipitated by factors that upregulate hepatic 5-aminolevulinic acid synthase 1 (ALAS1) activity.
87 actors that induce the expression of hepatic 5-aminolevulinic acid synthase 1 (ALAS1) result in the a
88                     In this work, we uncover 5-aminolevulinic acid synthase 1 (ALAS1), the initiating
89                     Marked overexpression of 5-aminolevulinic acid synthase 2 (Alas2) results from lo
90 oblastic anemia (XLSA) in female carriers of 5-aminolevulinic acid synthase 2 mutations is not uncomm
91      These knock-out parasite lines, lacking 5-aminolevulinic acid synthase and/or ferrochelatase (FC
92 ms whereby increased cellular heme regulates 5-aminolevulinic acid synthase is by decreasing the stab
93 genase, and heme (200 nM); (c) Repression of 5-aminolevulinic acid synthase mRNA levels by zinc mesop
94 r a decrease in cellular heme might increase 5-aminolevulinic acid synthase mRNA stability and whethe
95          We found that: (a) The stability of 5-aminolevulinic acid synthase mRNA was markedly increas
96 eferoxamine; (b) This increased stability of 5-aminolevulinic acid synthase mRNA was reversed by the
97 romium mesoporphyrin significantly decreased 5-aminolevulinic acid synthase mRNA without increasing h
98 , heme-like, effect of zinc mesoporphyrin on 5-aminolevulinic acid synthase mRNA; (d) Among the sever
99                                      Hepatic 5-aminolevulinic acid synthase, the first and normally r
100                                              5-Aminolevulinic acid synthesis rates are increased and
101   In conjunction with the dark repression of 5-aminolevulinic acid synthesis, GUN4 phosphorylation mi
102 h codes for one of two isoenzymes catalyzing 5-aminolevulinic acid synthesis.
103 ions, respectively, in the erythroid form of 5-aminolevulinic acid synthetase (ALAS), ALAS2, which en
104 code isozymes that catalyze the formation of 5-aminolevulinic acid, the first step in the biosynthesi
105  chlorophyll share common intermediates from 5-aminolevulinic acid through protoporphyrin IX.
106            We conjugated the photosensitizer 5-aminolevulinic acid to the lipophilic cation triphenyl
107 Previously, topical PDT using blue light and 5-aminolevulinic acid was found to be a potent stimulus
108 Furthermore, we show that the heme precursor 5-aminolevulinic acid, which is used as an antimicrobial
109 yl-5-aminolevulinic acid is an ester form of 5-aminolevulinic acid with improved uptake by tumor cell

 
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