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1 y of C2/AS monolayers compared with C2/CEP4 (50% effective doses at 30 minutes were 0.53 +/- 0.11 and
2 ckade of climbing was very potent with an ED(50) (effective dose at 50% of maximum) of 16 microgram/k
3 IgG) and Fab cleared the infection with i.n. 50% effective doses (ED(50)s) of 16 and 90 pmol, respect
4 e highest specific activity against both A2 (50% effective dose [ED(50)] = 0.28 +/- 0.11 microg/ml) a
5 [3H]ryanodine in a reversible manner with a 50% effective dose (ED50) of 0.16 microM without alterin
8 concentration in the culture medium, and the 50% effective dose for L-Arg was 220 microM, which is ab
10 e with doses equivalent to approximately 100 50% effective doses of Yersinia pestis strain CO92 and n