ライフサイエンスコーパス: A-fiber

1 A fiber adapter assembly and gas filling setup was desig

2 A fiber optic bead-based sensor array platform has been

3 A fiber optic microsphere-based oligonucleotide array is

4 A fiber optic particle plasmon resonance (FOPPR) immunos

5 A fiber optic probe consisting of a 1.0 mm coherent imag

6 A fiber optic salivary cortisol sensor using a contempor

7 A fiber optic with a ring electrode can also be used to

8 A fiber-based laser with a pulse duration of 435 fs and

9 A fiber-based subdivision successfully separates lobar r

10 A fiber-deficient diet exacerbated microbiota collapse a

11 A fiber-deleted, propagation-defective rescue plasmid ha

12 A fiber-elastomer composite design with a vastly improve

13 A fiber-free exclusive enteral nutrition diet also induc

14 A fiber-optic assay for amplified DNA products has been

15 A fiber-optic biosensor array is described for the simul

16 A fiber-optic biosensor using an aptamer receptor has be

17 A fiber-optic bundle was used for the gas detection and

18 A fiber-optic bundle, positioned approximately 2 mm from

19 A fiber-optic coupled attenuated total reflection (ATR)-

20 A fiber-optic fiber attached to a bundle of drivable mic

21 A fiber-optic microbial biosensor suitable for direct me

22 A fiber-optic OCT imaging system was used to image the m

23 A fiber-optic periodontal endoscope was developed to aid

24 A fiber-probe-based Raman spectroscopy method combined w

25 A fiber-type sweat sensor was woven with strain and ligh

26 each DCN from T6 to L1 at 0.5 mA to activate A-fiber alone or 5 mA to activate both A- and C-fibers a

27 Additional A-fiber activation by stimulating up to 4 adjacent DCNs

28 In addition, the role of afferent A-fiber and C-fiber activation of CVNs was examined.

29 data show, therefore, that primary afferent A-fiber activity can cause neuronal cell death in the do

30 including the refinement of primary afferent A-fiber terminals from superficial to deeper spinal dors

31 rs, was used to examine the role of afferent A-fibers and C-fibers in the synaptic activation of CVNs

32 ed whether activity in myelinated afferents (A fibers), which use glutamate as a transmitter, can ind

33 been implicated in mechanical allodynia, an A-fiber-selective pharmacological blocker is still lacki

34 data provide evidence that both C-fiber and A-fiber nociceptors may encode high-intensity mechanical

35 conditioning stimulation was as effective as A-fiber stimulation alone.

36 onduction failure in large myelinated axons (A fibers) mirrored the time course of glycogen loss.

37 Both A-fiber and C-fiber synapses recovered from STD at a sim

38 h force over a large stimulus range for both A-fiber and C-fiber nociceptors.

39 ons in phenotype includes the acquisition by A fibers of neurochemical features typical of C fibers,

40 OF mice) displayed only a mild decrease in C:A-fiber ratio compared with wild-type mice (4.42 compare

41 eficit manifested as a substantially lower C:A-fiber ratio compared with other mammals.

42 nerves, the naked mole-rat had the lowest C:A-fiber ratio ( approximately 1.5:1 compared with approx

43 le P2ry1 neurons are largely fast-conducting A fibers that contact pulmonary endocrine cells (neuroep

44 sed with neurofilament-200 in large-diameter A-fiber neurons in the dorsal root ganglion (DRG).

45 locus coeruleus neurons consist of an early (A-fiber mediated) component and a previously undescribed

46 is the larger-diameter mechanoreceptors (eg, A -fibers), rather than small-diameter pruriceptive C-fi

47 iber-driven spinal hyperexcitability enables A fibers to gain access to specific spinal circuitry, vi

48 For A-fiber and C-fiber nociceptors, we systemically measure

49 our findings suggest that FST, released from A-fiber neurons, enhances Nav1.7-mediated hyperexcitabil

50 Although large, myelinated group A fibers, in particular Abeta-fibers, have previously be

51 However, A fibers, but not C fibers, in the injured L5 spinal ner

52 iii), A fiber conformation can stabilize a regular spacing of

53 accelerated CAP failure during aglycemia in A fibers, but not in C fibers.

54 ensory neurons including novel expression in A fibers, has a role as a central modulator of tactile s

55 lockade of sodium currents, predominantly in A-fiber neurons of mouse DRGs.

56 Here, we report that FST was up-regulated in A-fiber sensory neurons after spinal nerve ligation (SNL

57 f both isoforms, while cutaneous CTB-labeled A fibers exclusively expressed synaptophysin.

58 Elimination of large A-fiber carotid baroreceptor afferents, during similar c

59 ompared to that during anodal block of large A-fibers in the carotid sinus nerve.

60 ese data indicate that projections of larger A-fiber (type I) carotid baroreceptors are localized pri

61 At both levels, A fibers projected to deeper layers of the dorsal horn t

62 alized in 90% of DRG neurons, including most A-fibers (identified by the presence of neurofilament 20

63 Here we identified two populations of murine A fiber-type sensory neurons that display markedly diffe

64 cholera toxin subunit B (CTB) for myelinated A fibers and isolectin B4 (IB4) for unmyelinated C fiber

65 g all neuronal classes, including myelinated A fibers and unmyelinated C fibers.

66 expression was increased in large myelinated A-fiber DRG neurons, whereas it was decreased in small u

67 nduced ultrastructural changes in myelinated A-fibers.

68 inated C-fibers usually outnumber myelinated A-fibers.

69 psaicin persistently reduces C-fiber but not A-fiber compound action potentials and this effect does

70 trocutaneous stimulation at C-fiber, but not A-fiber, strength produced behavioral signs of secondary

71 This novel A fiber input was polysynaptic in nature and required NM

72 in detectable neuron loss, but activation of A fibers in a previously sectioned sciatic nerve did cau

73 Repeated activation of A-fiber inputs to the SDH evoked short-term depression (

74 subclass is similar to a mammalian group of A-fiber sensory neurons.

75 approximately 10%) colabeled with markers of A-fiber neurons.

76 itive cells and a more diverse population of A-fiber neurons, some of which exhibit T-type Ca2+ chann

77 in either sex prevents the normal process of A-fiber refinement and elimination, resulting in an alte

78 , particularly relating to the processing of A-fiber nociceptive information.

79 Because slowing of A-fiber conduction velocities had also been demonstrated

80 The expansion of the territory of A-fiber afferent-evoked cell death is likely to reflect

81 t early and late phases, whereas blockade of A-fibers only suppressed late-phase itch.

82 .3-1.5 times the threshold for excitation of A-fibers.

83 roots and reduced the thermal sensitivity of A-fibers.

84 eport a new method for targeted silencing of A-fibers in neuropathic pain.

85 copic sections, we found that stimulation of A-fibers in an intact sciatic nerve at 10 Hz, 20 Hz, and

86 In addition, mean conduction velocities of A-fibers and C-fibers in vincristine-treated rats were s

87 -fibers whereas HR changes were dependent on A-fibers.

88 Low-intensity stimuli or A-fiber input had no effect.

89 esident immune cells in the CNS, phagocytose A-fiber terminals in superficial laminae in the first we

90 g NK1 receptor (NK1R-) received polysynaptic A fiber input.

91 Neurofilament-positive A-fiber neurons innervating the distal urethra had a lar

92 determined via Hoffmann's reflex (H-reflex) (A-fiber), was decreased in diabetic compared with contro

93 ibute to different cardiovascular responses, A-fibers to HR and C-fibers to BP, with temporal (stimul

94 abolished by local anesthetic and selective A-fiber blockade.

95 nding that a subgroup of capsaicin-sensitive A-fiber nociceptors are insensitive to heat predicts the

96 (300 nm), respectively, revealed significant A fiber input to lamina I NK1R+ neurons that was predomi

97 ntial (AP) activity was recorded from single A-fiber nociceptors that innervated the hairy skin in mo

98 bsence of microglial engulfment, superfluous A-fiber projections remain in the dorsal horn, and the b

99 hus, glycine may serve to facilitate tactile A-fiber-mediated information and enhance activity-depend

100 These results suggest that A-fiber nociceptors play a role in the pain and hyperalg

101 response of LC neurons without affecting the A-fiber response component.

102 to the afferent stimulation of CVNs, and the A-fiber GABAergic pathway to CVNs may be more complex th

103 ty is dominated by inputs from low threshold A fibers, whereas nociceptive C-fiber inputs mature grad

104 nce of monosynaptic input from low-threshold A-fibers when preceded by early tissue damage.

105 bitory neurons with monosynaptic contacts to A-fiber sensory neurons gated pain transmission independ

106 itude resulted from altering the response to A-fiber inputs to the trigeminal nerve because all stimu

107 itch sensation differs between subjects with A-fiber- versus C-fiber-dominated itch, (3) cowhage acti

108 ime of peak itch sensation for subjects with A-fiber-dominated itch matches the time for peak respons

109 reduces itch in a subgroup of subjects with A-fiber-dominated itch, (2) the time course of itch sens