ライフサイエンスコーパス: AMPA

1 AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propion

2 AMPA and kainate receptors, along with NMDA receptors, r

3 AMPA receptor plasticity mediated by the GluA1 subunit p

4 AMPA receptors (AMPARs) are tetrameric ligand-gated chan

5 AMPA receptors and interacting proteins are importantly

6 AMPA receptors are tetrameric assemblies composed of fou

7 AMPA receptors mediate fast excitatory neurotransmission

8 AMPA subtype ionotropic glutamate receptors mediate fast

9 AMPA was quantified in nine samples up to 40 ng/g.

10 AMPA- and NMDA-type glutamate receptors mediate distinct

11 AMPA-type glutamate receptors (AMPARs) mediate excitator

12 AMPA-type glutamate receptors (AMPARs) mediate fast exci

13 AMPA-type glutamate receptors (AMPARs), which mediate fa

14 variants, and those variants, as in GluA2-4 AMPA receptor subunits, generally show different propert

15 Pentraxin then accumulates AMPA receptors on the postsynaptic terminal forming func

16 aluminium, glufosinate, glyphosate, N-acetyl AMPA, N-acetyl glyphosate, perchlorate and phosphonic ac

17 determination of aminomethylphosphonic acid (AMPA) was also facilitated via minor modification of the

18 f glyphosate and aminomethylphosphonic acid (AMPA).

19 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor (AMPAR) abundance, which is modulated by

20 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor (CP-AMPAR) currents after brain injury.

21 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor and mammalian target of rapamycin (mTOR)

22 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor plasticity plays a role in sustaining sei

23 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are glutamate-gated ion channels that me

24 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are two major, closely related receptor

25 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in vitro after exposure to patients' CSF

26 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type iGluRs using genetically encoded unnatural am

27 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type ionotropic glutamate receptors (AMPA receptor

28 -hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type subunit 2 (GRIA2) in neurons depended on FUS

29 ydroxy-5-methylisoxazol-4-yl)propanoic acid (AMPA) receptors have been reported, no such ligands are

30 ydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor subtypes, confirmed also by an unusual bi

31 hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) to N-methyl-D-aspartate (NMDA) ratios, and matrix

32 -hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type receptors is required for synaptopathy, and h

33 hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) receptors.

34 3-hydroxy-5-methyl-4-isoxazolepropionic acid(AMPA)-type glutamate receptors (AMPARs) are the predomin

35 l cortex pyramidal neurons without affecting AMPA EPSC currents.

36 s in postsynaptic response to GABA, and also AMPA, receptor activation include regulation of voltage-

37 dministration revealed that both drugs alter AMPA receptor-mediated synaptic transmission in CA3.

38 ing in hippocampal neurons, without altering AMPA receptor trafficking.

39 ght to the mechanism by which cocaine alters AMPA surface expression.

40 hrough age-dependent suppression of amygdala AMPA receptor subunit trafficking, (2) maternal presence

41 se antidepressant effects were blocked by an AMPA receptor antagonist.

42 f 8-OH-DPAT are blocked by co-infusion of an AMPA receptor antagonist or an anti-BDNF neutralizing an

43 oter to express AMPApHluorin (pHluorin on an AMPA receptor).

44 molecular dynamics simulations to predict an AMPA receptor open state structure and rationalize the r

45 lesser extent by AMPA receptors, whereas an AMPA receptor-mediated excitation prevails in Group II m

46 g the localization of potassium channels and AMPA receptors, respectively.

47 tively increased dendritic spine density and AMPA-receptor-mediated EPSCs in wild-type neurons, but n

48 buse, and mesolimbic dopamine engagement and AMPA were not significantly altered by maternal presence

49 dynamic clamp was used to simulate GABA and AMPA conductances.

50 Both GABA and AMPA dynamic clamp-induced postsynaptic potentials (PSPs

51 ons with PolyP reduced glutamate-induced and AMPA-induced but not the NMDA-induced calcium signal.

52 The effect of PolyP on glutamate-induced and AMPA-induced calcium signal is dependent on P2Y receptor

53 f homodimers and heterodimers of kainate and AMPA receptors using fluorescence-detected sedimentation

54 designed to individually inhibit kainate and AMPA receptors.

55 to find that mGluR activation causes LTD and AMPA receptor internalization, but no spine shrinkage in

56 T3 accompanied chemical induction of LTD and AMPA receptor internalization.

57 s where it regulates spine morphogenesis and AMPA receptor confinement.

58 inutes later, dendritic spine morphology and AMPA to NMDA ratios were restored as animals became moti

59 LTP of NMDA and AMPA EPSCs after high-frequency stimulation was reduced

60 t glutamate activates TRESK through NMDA and AMPA mediated calcium influx and calcineurin activation

61 ces, PolyP reduced ion flux through NMDA and AMPA receptors in native neurons.

62 functions transsynaptically control NMDA and AMPA receptors, thereby mediating presynaptic control of

63 We observe that antagonism of NMDA and AMPA type glutamate receptors protects neurons from cond

64 We recorded neuronal glutamatergic (NMDA and AMPA) responses in prefrontal cortex (PFC) neurons and u

65 reduction of both NMDA receptor (NMDAR) and AMPA/kainate receptor-mediated evoked excitatory postsyn

66 domains of both NMDA receptors (NMDARs) and AMPA receptors (AMPARs) have distinct motifs, which are

67 kinase A (PKA), protein kinase C (PKC), and AMPA receptor genes that play a pivotal role in memory f

68 ptor surface expression and trafficking, and AMPA receptor-mediated synaptic transmission.

69 nel, a Food and Drug Administration-approved AMPA receptor (AMPAR) antagonist, during a follow-on 24-

70 diazine 1,1-dioxides and their evaluation as AMPA receptor positive allosteric modulators (AMPApams).

71 stsynaptic ligand-gated ion channels such as AMPA receptors (AMPARs) are organized into so-called nan

72 ased by vagal afferents, glutamate acting at AMPA receptors and 5-HT acting at 5-HT(2A) receptors.

73 cNIC decreased baseline AMPA/NMDA ratio, arising from increased NMDA currents en

74 t al. (2017) dissect the interaction between AMPA receptors and auxiliary (TARP) subunits, revealing

75 to extensive hydrophobic interfaces between AMPA receptor subunits in the ion channel.

76 rly gene (IEG) expression and changes in BLA AMPA receptor (AMPAR) and NMDA receptor (NMDAR) subunit

77 Furthermore, FB9s-r blocked AMPA receptor activity.

78 dual activity for effectively blocking both AMPA and kainate receptors.

79 95 induction following learning impairs both AMPA receptor response maturation and infantile memory,

80 A aptamers that can potentially inhibit both AMPA and kainate receptors.

81 At synapses throughout the mammalian brain, AMPA receptors form complexes with auxiliary proteins, i

82 In the brain, AMPA-type glutamate receptors (AMPARs) form complexes wi

83 Unitary EPSCs were small and brief (AMPA receptor, approximately 1 nS, approximately 1 ms; N

84 by NMDA receptors and to a lesser extent by AMPA receptors, whereas an AMPA receptor-mediated excita

85 otentiation at these synapses as measured by AMPA/N-methyl-D-aspartate currents.

86 excitatory neurotransmission is mediated by AMPA-subtype ionotropic glutamate receptors (AMPARs).

87 ses to its release predominantly mediated by AMPA-type glutamate receptors (AMPARs).

88 n the mammalian brain is largely mediated by AMPA-type ionotropic glutamate receptors (AMPARs), which

89 Consistently, AMPA receptor antagonist CNQX or calcineurin inhibitor F

90 g the activation of PKA and GluA1-containing AMPA receptors (AMPARs).

91 Previously we reported that GluA1-containing AMPA receptors and their interaction with PDZ-proteins a

92 nclear if the expression of GluA1-containing AMPA receptors is affected by this type of behavior.

93 at the acute involvement of GluA1-containing AMPA receptors tor forced swim behavior is a result of n

94 reduced levels of membrane GluA1-containing AMPA receptors.

95 est that the endocytosis of GluR2-containing AMPA receptors in the amygdala regulates retrieval-induc

96 DAR)-mediated synaptic currents and decrease AMPA receptor (AMPAR)/NMDAR ratios in midbrain dopamine

97 postsynaptic bursting selectively depressed AMPA receptor (R) synaptic transmission, or silenced exc

98 cluded eight pesticides (desulfinylfipronil, AMPA, chlorpyrifos, dieldrin, metolachlor, atrazine, CIA

99 (LGI1, CASPR1, CASPR2); glutamate detection (AMPA-R); GABA regulation and release (GAD65, amphiphysin

100 distinct subdivisions of ACC with different AMPA/N-methyl-D-aspartate receptor profiles.

101 omain, which controls motions in the distant AMPA receptor N-terminal domain (NTD).

102 by the presence of glutamate receptors (i.e. AMPA, NMDA, and kainate receptors) at the synapse.

103 phrenia, RNA editing sites in genes encoding AMPA-type glutamate receptors and postsynaptic density p

104 Under basal conditions, endocytosed AMPA receptors are rapidly recycled back to the plasma m

105 conformational changes throughout the entire AMPA receptor that accompany activation and desensitizat

106 al gene expression levels between excitatory AMPA receptors (AMPARs) and inhibitory GABA(A) receptors

107 DNQX, by blocking excitatory AMPA glutamate inputs, is hypothesized to produce relati

108 tion led to an increase in surface-expressed AMPA receptors specifically in the neurons with MAP2 spi

109 , reduce levels of synaptic or extrasynaptic AMPA receptors, or alter other AMPA receptor trafficking

110 receptors akin to that of slow NMDA and fast AMPA EPSCs at glutamate synapses.

111 ctrochemical communication through bona fide AMPA receptor-dependent neuron-glioma synapses.

112 and strong upregulation of genes coding for AMPA receptor auxiliary subunits.

113 ized NAc neuronal inhibition is required for AMPA-blocking microinjections in medial shell to induce

114 Second, a reduction of functional AMPA receptors depends upon the phosphorylation of at le

115 Glutamate-gated AMPA receptors mediate the fast component of excitatory

116 ely spliced, flip and flop variants of GluA1 AMPA receptor subunit exhibit no functional difference i

117 g to phosphorylation of serine S845 on GluA1 AMPA receptors and their trafficking to the plasma membr

118 units, as we show for both kainate and GluA2 AMPA receptors.

119 An emerging model posits that the GluA2 AMPA receptor (AMPAR) subunit may be important for the b

120 molecular dynamics simulations of the GluA2 AMPA subtype glutamate receptor ligand-binding domain (L

121 Microinjections of a glutamate AMPA antagonist (DNQX) in medial shell of nucleus accumb

122 sed levels of the GluA1 subunit of glutamate AMPA receptor and display increased anxiety-like behavio

123 we examined the involvement of the glutamate AMPA receptor and brain-derived neurotrophic factor (BDN

124 sites at the GluA1 subunit of the glutamate AMPA receptors, which has been characterized as a critic

125 Gated by the neurotransmitter glutamate, AMPA receptors are critical for synaptic strength, and d

126 ls and altered organization of glutamatergic AMPA receptors in LRRK2 mutants.

127 Within the postsynaptic density, however, AMPA receptors coassemble with transmembrane AMPA recept

128 In AMPA receptor heteromers, TARP stoichiometry further mod

129 sed NMDA receptor function with no change in AMPA receptor function.

130 se effects are not accompanied by changes in AMPA and NMDA receptor properties at cortical, amygdaloi

131 Reelin is able to rescue the deficits in AMPA, NMDA, GABA(A) receptors, mTOR and p-mTOR induced b

132 P activation and t-SP induction (increase in AMPA currents in MSNs).

133 is occurs simultaneously with an increase in AMPA receptor currents, suggesting a high-to-low frequen

134 educed levels of EEA1, a protein involved in AMPA receptor endocytosis.

135 some antigen 1 (EEA1), a protein involved in AMPA-type glutamate receptor endocytosis.

136 ctin-dependent cellular processes, including AMPA receptor trafficking at synapses.

137 ered glycans in the disease state, including AMPA and kainate receptor subunits, glutamate transporte

138 -independent mechanism that drives increased AMPA receptor recycling and LTP.

139 hat self-administration of cocaine increases AMPA glutamate receptors in the VTA, and this effect enh

140 c diet), have been shown to directly inhibit AMPA receptors (glutamate receptors), and to change cell

141 wing MO treatment were reduced by inhibiting AMPA and NMDA receptors in the spinal cord.

142 tor subunit B, glutamate receptor ionotropic AMPA 2 (GRIA2), modifies a codon, replacing the genomica

143 changes is the remodeling of the ionotropic AMPA-type glutamate receptors that underlie fast excitat

144 creased synaptic expression of GluA2-lacking AMPA receptors, and blocked synaptic scaling, whereas in

145 These synapses have larger AMPA receptor- and NMDA receptor-mediated events.

146 naptic density protein-95 (PSD-95) localizes AMPA-type glutamate receptors (AMPARs) to postsynaptic s

147 However, many AMPA and kainate receptor complexes in vivo are heterome

148 We also determined whether modified AMPA receptors generated during status epilepticus could

149 However, how TARPs modulate AMPA receptor gating remains poorly understood.

150 of Bin1 lead to changes in spine morphology, AMPA receptor surface expression and trafficking, and AM

151 Most AMPA receptors (AMPARs) are heteromeric complexes of sub

152 Phrenic motoneuron AMPA glutamate receptor 2 (GluR2) subunit mRNA expressio

153 g to the incentive stimulus depended on NAcC AMPA/NMDA and dopamine D1 receptors, but the retrieval o

154 ucidate the structures of 10 distinct native AMPA receptor complexes by single-particle cryo-electron

155 rangement, and molecular structure of native AMPA receptors remain unknown.

156 lies comprising a major population of native AMPA receptors.

157 d in animals (e.g., antibodies against NMDA, AMPA receptors, LGI1 protein) or in cultured neurons (e.

158 GABA(A) receptor antagonist, but not an NMDA/AMPA/kainate receptor antagonist, suggesting that they w

159 ng an EE experience not only restored normal AMPA-receptor expression levels but also reversed the in

160 Hyperpolarizing current injection, but not AMPA receptor blockade, prevents synaptic stimulation fr

161 postsynaptic NMDA-receptor-mediated, but not AMPA-receptor-mediated, synaptic responses without alter

162 uce postsynaptic AP firing in the absence of AMPA receptors.

163 g to subsequent C demand and accumulation of AMPA.

164 ntidepressant-like effects via activation of AMPA receptor/BDNF/mTOR signaling in mice, which subsequ

165 Prolonged application of AMPA caused loss of afferent terminal responsiveness, wh

166 is generally weaker than the association of AMPA receptor ATD dimers, but both show a general patter

167 The amino-terminal domain (ATD) of AMPA receptors (AMPARs) accounts for approximately 50% o

168 d Proteins (TARPs), which mediate binding of AMPA-type glutamate receptors to PSD-95, was increased i

169 he surface levels and synaptic clustering of AMPA glutamate receptors.

170 itro blocked LTP-induced surface delivery of AMPA receptors and spine enlargement.

171 tase 2B (PP2B)-mediated dephosphorylation of AMPA receptors can determine whether LTD or LTP occurs i

172 We pioneer the first description of AMPA receptor (AMPAR)-mediated currents in the PNS glia

173 for synaptic strength, and dysregulation of AMPA receptor-mediated signalling is linked to numerous

174 gs on neural excitability and the effects of AMPA and NMDA receptor blockers on functional connectivi

175 resulted in increased surface expression of AMPA receptor subunits GluA1 and GluA2.

176 pression increases the surface expression of AMPA receptor subunits, providing insight to the mechani

177 ce levels and the amplitude and frequency of AMPA receptor-mediated currents, and mimicked excitatory

178 ed transcription, expression and function of AMPA and NMDA receptors.

179 to induce spinogenesis and the generation of AMPA receptor-silent glutamatergic synapses in the adult

180 The identification of AMPA, kainate and NMDA glutamate receptor subtypes by Wa

181 ocomotor responses to intra-VTA infusions of AMPA, suggesting a paradoxical increase in VTA AMPA rece

182 e Thorase to regulate the internalization of AMPA receptors (AMPARs) in order to selectively manipula

183 dendritic spine pruning, internalization of AMPA receptors and long-term depression.

184 azole chemistry enables covalent labeling of AMPA-type glutamate receptors in the same brain regions.

185 ation that enhanced the expression levels of AMPA-type glutamate receptors.

186 sition distinct from that of the majority of AMPA receptors that dominate the horizontal cell postsyn

187 The free energy maps of AMPA and kainate receptor ATD dimers provide a framework

188 in and PSD-95, and significant maturation of AMPA receptor synaptic responses.

189 We present the first model of AMPA receptor phosphorylation that simulates the inducti

190 a hub for powerful allosteric modulation of AMPA receptor function that can be used for developing n

191 trate that positive allosteric modulation of AMPA receptors by PAM-AMPA treatment reverted memory, bu

192 ggest that positive allosteric modulation of AMPA receptors restores synaptic integrity and cognitive

193 ng through positive allosteric modulation of AMPA receptors, by the use of a PAM-AMPA compound.

194 Negative allosteric modulators of AMPA receptors are considered to have significant therap

195 Glioma-cell-specific genetic perturbation of AMPA receptors reduces calcium-related invasiveness of t

196 ic receptors regulate the phosphorylation of AMPA receptor subunit GluA1 via a signaling pathway link

197 nt amplitude and alter kinetic properties of AMPA receptors on slow time scale, such as desensitizati

198 Whether TARPs affect the rate of AMPA channel opening and closing, however, remains elusi

199 How Ca(2+) induces the recruitment of AMPA receptors remains unclear.

200 es to spines, enhances synaptic recycling of AMPA receptors to increase their surface expression and

201 Regulation of AMPA receptor (AMPAR) expression is central to synaptic

202 t miRNA-mediated mechanism for regulation of AMPA receptor expression.

203 Regulation of AMPA-type glutamate receptor (AMPAR) number at synapses

204 Its expression is mediated by the removal of AMPA receptors from postsynaptic membranes.

205 have evolved to optimize rapid responses of AMPA-type iGluRs at synapses.

206 notropic glutamate receptors and the role of AMPA receptors in excitatory neurotransmission.

207 orm of homeostatic plasticity, up-scaling of AMPA-glutamate receptors.

208 ng other kinetic properties, for a series of AMPA channels with different arginine/glycine (R/G) edit

209 but also ones including the GluA2 subunit of AMPA receptors (AMPARs).

210 d of synaptic levels of the GluA1 subunit of AMPA-type glutamate receptors after 48 h silencing with

211 GRIA3 encodes GluA3, a subunit of AMPA-type ionotropic glutamate receptors (AMPARs).

212 of synaptic strength through trafficking of AMPA receptors (AMPARs) is a fundamental mechanism under

213 osomal sorting complex in the trafficking of AMPA receptors during NMDA-receptor-dependent LTP at mat

214 ent with the role of synaptic trafficking of AMPA-type of glutamate receptors in HSP, Mecp2 KO neuron

215 neurexin-2 at SS4 had no effect on NMDA- or AMPA-receptor-mediated responses.

216 no immediate effect on glutamate release or AMPA-mediated neurotransmission.

217 extrasynaptic AMPA receptors, or alter other AMPA receptor trafficking events.

218 ation of AMPA receptors, by the use of a PAM-AMPA compound.

219 losteric modulation of AMPA receptors by PAM-AMPA treatment reverted memory, but not mood, deficits.

220 Furthermore, PAM-AMPA treatment reverted stress/Abeta-driven synaptic mis

221 ion but, instead, requires Ca(2+) -permeable AMPA receptors and group I metabotropic glutamate recept

222 ation through Ca(2+)- (and Zn(2+))-permeable AMPA channels in CA3 and Zn(2+) mobilization from MT-III

223 akin to Hebbian plasticity: Ca(2+)-permeable AMPA receptor upregulation, L-type Ca(2+) channel activa

224 this regimen; furthermore, Ca(2+)-permeable AMPA receptors (CP-AMPARs) increase in the NAc core afte

225 ulation of high conductance Ca(2+)-permeable AMPA receptors (CP-AMPARs) that is detectable with elect

226 nvolvement of GluA2-lacking Ca(2+)-permeable AMPA receptors (CP-AMPARs) using IEM-1460, which has bee

227 nced relative expression of Ca(2+)-permeable AMPA receptors at muscle afferent synapses drives greate

228 hydrobromide (IEM-1460), a calcium-permeable AMPA receptor antagonist, was determined.

229 Calcium-permeable AMPA receptors modified during status epilepticus can be

230 turation by recruitment of calcium-permeable AMPA-type glutamate receptors (CP-AMPARs) after drug wit

231 y the recruitment of additional postsynaptic AMPA receptors (AMPARs), sourced either from an intracel

232 with presynaptic neurexins and postsynaptic AMPA-type ionotropic glutamate receptors and induced the

233 n Vglut3(WT) were maintained as postsynaptic AMPA receptors juxtaposed with presynaptic ribbons and v

234 g in the accumulation of excess postsynaptic AMPA receptors and defective synaptic plasticity.

235 How postsynaptic AMPA- and NMDA-receptor levels are regulated, however, r

236 loss of presynaptic ribbons or postsynaptic AMPA receptors was not observed in Vglut3(KO) , demonstr

237 argazer (stg/stg) mice bearing a presynaptic AMPA receptor defect, but not homozygous tottering (tg/t

238 o-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA) receptors, RNA editing and alternative splicing ge

239 -3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) throughput.

240 -5-methyl-4-isoxazolepropionic acid receptor AMPA receptor subunit 1 (GluA1) through phosphorylation

241 B (GRIN2B) and glutamate ionotropic receptor AMPA-type subunit 2 (GRIA2).

242 (AMPA)-type ionotropic glutamate receptors (AMPA receptors) predetermines responsiveness to neurotra

243 of active excitatory synapses by recruiting AMPA glutamate receptors to the postsynaptic cell surfac

244 teral amygdala (BLA), and plasticity-related AMPA receptor subunit trafficking.

245 isengage both the BLA and plasticity-related AMPA receptor subunit trafficking.

246 A survey of iGluR gene expression revealed AMPA-, Kainate-, and NMDA-type subunits are expressed in

247 ands by exponential enrichment with a single AMPA receptor target (i.e. GluA1/2R) to isolate RNA apta

248 generate action potentials evoked by single AMPA-dependent EPSPs.

249 We developed a statistical AMPA-receptor-tetramer model, which permits the estimati

250 nnings for these memory dynamics, we studied AMPA receptor (AMPAR)-silent excitatory synapses, which

251 re and used a patch-clamp technique to study AMPA-receptor (AMPAR)-mediated currents in SCs for the f

252 ive splicing of neurexin-3 at SS4 suppressed AMPA-receptor-mediated, but not NMDA-receptor-mediated,

253 post-synaptic scaffold that captures surface AMPA receptors.

254 mplitudes, indicating an increase in surface AMPA receptor levels compared with wild-type neurons.

255 +) influx stimulates recruitment of synaptic AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propion

256 mission by promoting the removal of synaptic AMPA receptors (AMPARs), dendritic spine loss, and synap

257 mutations result in either reduced synaptic AMPA receptor expression or enhanced glutamatergic synap

258 in dentate granule neurons reduces synaptic AMPA receptor function and causes dendritic spines to ad

259 We built structural models of TARP-AMPA receptor complexes for TARPs gamma2 and gamma8, com

260 the effect on PSPs in silico, revealing that AMPA PSPs were more sensitive to changes in capacitance.

261 The AMPA receptor (AMPAR) subunit GluA3 has been suggested t

262 The AMPA subtype of synaptic glutamate receptors (AMPARs) pl

263 scimol (1/0.1 mM) into unilateral PL and the AMPA receptor antagonist NBQX (1 mM) into contralateral

264 owth are also reduced by anaesthesia and the AMPA receptor antagonist perampanel, respectively.

265 a (15-fold), GluK1b (5-fold), as well as the AMPA receptor subunit GluA1i (5-fold).

266 te within the 3'UTR of the mRNA encoding the AMPA receptor GluA2 subunit, and demonstrate that GluA2

267 Following ER exit, the AMPA-type glutamate receptor GluA1 and neuroligin 1 unde

268 et al. (2017) reveal a critical role for the AMPA receptor subunit GluA3 in cerebellar synaptic plast

269 ronic blockade of glutamate receptors of the AMPA and NMDA types in hippocampal neurons in culture in

270 Injection of the AMPA antagonist CNQX blocked the rescue of the behaviora

271 l with an increase in phosphorylation of the AMPA GluA1 receptor subunit at serine 831 (S831), a CaMK

272 Glypican 4 induces release of the AMPA receptor clustering factor neuronal pentraxin 1 fro

273 ene decreased the synaptic expression of the AMPA receptor GluA2 and GluA3 subunits, but not the GluA

274 lts, and the fact that other subunits of the AMPA receptor have already been associated with neurodev

275 cterized, the mechanism of modulation of the AMPA subtype is much less known.

276 t are mediated by glutamate receptors of the AMPA subtype.

277 ccumulation or removal, respectively, of the AMPA-receptor regulatory scaffold protein A-kinase ancho

278 r model, which permits the estimation of the AMPA-receptor-mediated maximal synaptic conductance base

279 pses on PV interneurons are dependent on the AMPA receptor subunit GluA4, which is regulated by presy

280 f PolyP on glutamate and specifically on the AMPA receptors was dependent on the presence of P2Y1 but

281 is due to the effect of this polymer on the AMPA receptors.

282 KEY POINTS: The AMPA-type ionotropic glutamate receptors (AMPARs) mediat

283 s previously overlooked site proximal to the AMPA receptor channel gate.

284 r the crystal structures in complex with the AMPA receptor GluA2 agonist-binding domain.

285 ular insight into how NAMs interact with the AMPA receptor, which is of potential use for future desi

286 PolyP reduced calcium signal acting through AMPA receptors, thus protecting neurons against glutamat

287 Ionic currents through AMPA receptor channels can be allosterically regulated v

288 elicit changes in synaptic efficacy through AMPA receptor (AMPAR) endocytosis.

289 ptic sodium entry is almost entirely through AMPA receptors with little contribution from entry throu

290 e transformation from full mineralization to AMPA formation.

291 as patients' CSF did not alter responses to AMPA receptor agonists and was abrogated by preabsorptio

292 Previous studies tracking AMPA receptor (AMPAR) diffusion at synapses observed a l

293 Transmembrane AMPA receptor (AMPAR) regulatory proteins (TARPs) modula

294 xample, the ratio to PSD-95 of Transmembrane AMPA-Receptor-associated Proteins (TARPs), which mediate

295 As auxiliary subunits, transmembrane AMPA receptor regulatory proteins (TARPs) are known to e

296 AMPA receptors coassemble with transmembrane AMPA receptor regulatory proteins (TARPs), yielding a re

297 y fibre inputs to CbN cells generate unitary AMPA receptor EPSCs of approximately 1 nS that decay in

298 alter synaptic connectivity as measured via AMPA-receptor-mediated synaptic responses at Schaffer-co

299 PA, suggesting a paradoxical increase in VTA AMPA receptor responsiveness.

300 3)-(15)N co-labeled glyphosate turnover with AMPA formation in water-sediment systems (OECD 308).