ライフサイエンスコーパス: Ab

1 Ab and toluidine blue attached to O-succinyl-chitosan-ma

2 Ab cross-linking of HLA class I (HLA I) molecules on the

3 Ab depletion studies showed neuritis still developed in

4 Ab initio calculation and soft X-ray absorption spectros

5 Ab initio calculations reveal an intercalation-type dopi

6 Ab initio methods, such as coupled-cluster, routinely pr

7 Ab initio modeling of SANS shows that the oligomers form

8 Ab initio molecular dynamics (AIMD) simulations confirm

9 Ab initio molecular dynamics simulations show these high

10 Ab titers were measured using ELISA in healthy women (n

11 Ab-dependent cell cytotoxicity (ADCC) is a common effect

12 Ab-initio computations support the findings of two disti

13 Ab-mediated depletion of IL-1alpha in WT mice prevented

14 Ab-mediated targeting of CD25 is being actively pursued

15 Abs are glycoproteins that carry a conserved N-linked ca

16 Abs of the IgG isotype mediate effector functions like A

17 Abs recognizing the V2 peptide that was reported as a cr

18 Depletion of NK cells by anti-NK1.1 Abs drastically improved cognitive function of 3xTg-AD m

19 Interestingly, IL-12 and anti-IL-10 Abs improved T cell proliferation inhibited by AmB.

20 we generated a new monoclonal anti-Siglec-15 Ab to clarify its expression pattern on immune cells.

21 s for specific detection of human SARS-CoV-2 Abs against the receptor-binding domain, including an Ag

22 d bridging assays reliably detect SARS-CoV-2 Abs in hospitalized and nonhospitalized patients and are

23 bridging assays for detection of SARS-CoV-2 Abs to the receptor-binding domain (RBD) and nucleocapsi

24 tumors following administration of anti-41BB Abs.

25 these subunits can then bind anti-cluster A Abs.

26 Although B cell disorders and the aberrant Ab production are the leading extrahepatic manifestation

27 enty-one OMG patients with seropositive AchR Ab presented during July 2009 and December 2016.

28 OMG patients with seropositive AchR Ab should be informed that taking pyridostigmine and/or

29 y untested AChR-Ab positive MG sera, 10 AChR-Ab negative MG sera and 5 healthy control sera were then

30 first demonstrated by applying maternal AChR-Ab positive plasmas known to inhibit fetal AChR function

31 The maternal AChR-Ab positive plasmas reduced fetal AChR currents, but not

32 Eleven previously untested AChR-Ab positive MG sera, 10 AChR-Ab negative MG sera and 5 h

33 a(-) NK cells responded robustly to adaptive Ab-mediated signaling through CD16.

34 Moreover, we showed that a CD27 agonist Ab reversed the effects of CD70 ablation, indicating tha

35 IMP761 is a LAG-3-specific humanized agonist Ab with immunosuppressive properties both in vitro and i

36 functionality and potential of the agonistic Ab in the context of pathogenic aHUS-related FH mutant p

37 gs suggest that the effect of 41BB agonistic Abs are supported by additional costimulatory signals fr

38 n of 41BB costimulatory signals by agonistic Abs enhances the expansion and function of tumor-infiltr

39 hich are produced by gradual reduction of an Ab concentration to an extremely low level.

40 we assessed the therapeutic potential of an Ab raised to a modified survivin peptide but cross-react

41 To investigate the role of IL-10, we used an Ab to neutralize IL-10 in cynomolgus macaques during M.

42 In this study, we analyzed Ab-secreting cell and Ab responses in 20 hospitalized CO

43 olic programs regulate B cell activation and Ab responses.

44 b-dependent cellular phagocytosis (ADCP) and Ab-dependent neutrophil phagocytosis (ADNP) activities i

45 of protective immunity, yet human B cell and Ab responses during COVID-19 are not fully understood.

46 his study, we analyzed Ab-secreting cell and Ab responses in 20 hospitalized COVID-19 patients.

47 OVID-19 patients, with a focus on B cell and Ab responses, and describes tools to study immune respon

48 lower of Ag-specific CD4(+) T cell count and Ab titers in mice.

49 like Ab-dependent cellular cytotoxicity and Ab-dependent cellular phagocytosis by Fc interactions wi

50 b-54149 than an antibody purified from anti- Ab-54149 EPS serum.

51 These results suggested that the anti-Ab-54149 EPS serum would exhibit cross-reactivity to Pse

52 Detection of HLA antibodies (Ab) was performed by Luminex assay.

53 Though polyclonal and monoclonal antibodies (Ab) can provide complete protection against bubonic plag

54 licated by concern that elicited antibodies (Abs) may cross-react with other flaviviruses that share

55 al problem and are driven by IgE antibodies (Abs) specific for food antigens (Ags).

56 and cytomegalovirus-neutralizing antibodies (Abs).

57 atural infection is neutralizing antibodies (Abs).

58 tivity and enhance the number of antibodies (Abs) immobilized on the electrode surface.

59 nce of generating polyfunctional antibodies (Abs).

60 Engineering sequence-specific antibodies (Abs) against phosphotyrosine (pY) motifs embedded in fol

61 technique that uses metal-tagged antibodies (Abs) for high-dimensional single-cell immunoassays.

62 of bovine serum albumin (BSA) and antibody (Ab) enhanced the dispersity of the self-assembled nanopa

63 oligodendrocyte glycoprotein (MOG) antibody (Ab) dynamics between children and adults with MOG-Ab-ass

64 Using L. tropica specific antibody (Ab)-mediated phagocytosis assays, we could substantiate

65 No donor-specific human leukocyte antigen Abs or rejection episodes were noted, even though the pa

66 h elevated serum levels of BAFF, antinuclear Abs (ANA) and immune complexes.

67 of human SLE, develops elevated antinuclear Abs and immune complex-mediated nephritis along with oth

68 responsible for production of antiretrovirus Abs in I/LnJ mice.

69 3 ligases can act as cofactors for antitumor Abs that target cell surface proteins, suggesting that t

70 potential targets for therapeutic antitumor Abs.

71 ve vaccines to generate protective antiviral Ab responses.

72 Antiviral Abs were measured by ELISA.

73 ammaRIIIa, including the clinically approved Ab cetuximab.

74 ents with NMOSD (n=39, 28 aquaporin-4 (AQP4)-Ab-seropositive, 3 double-Ab-seronegative, 4 myelin olig

75 lycoprotein (MOG)-Ab-seropositive and 4 AQP4-Ab-seronegative with unknown MOG-Ab-serostatus), multipl

76 r pattern of elevation in patients with AQP4-Ab-seropositive NMOSD.

77 ocks Fc-mediated effector functions, such as Ab-dependent cellular cytotoxicity.

78 immunoglobulin G (IgG) autoantibodies (auto-Abs) against interferon-omega (IFN-omega) (13 patients),

79 set of critical disease; a few also had auto-Abs against the other three type I IFNs.

80 The auto-Abs neutralize the ability of the corresponding type I I

81 Patients with auto-Abs were aged 25 to 87 years and 95 of the 101 were men.

82 -switched IgG1, IgG2b, and IgG3 autoreactive Abs that depended on the epitope density.

83 ting stimulus, staphylococcal enterotoxin B, Abs to CTLA-4 and PD-1 reversed HIV latency in prolifera

84 eme iron containing Acinetobacter baumannii (Ab) oxygenase CntA/reductase CntB is implicated in the o

85 T cells are of considerable interest because Abs may enhance infection susceptibility.

86 phocytes have immunological functions beyond Ab production and may produce cytokines and chemokines t

87 ients with high NAb titers, viral Ag binding Abs were detectable in EIA tests.

88 tivity was adhesion dependent, as a blocking Ab against CD11b significantly reduced adhesion, degranu

89 we show that the anti-human alpha6-blocking Ab P5G10 induces apoptosis in primary ALL cells in vitro

90 at the same concentration of CD11b blocking Ab, S. aureus killing by female BMN was greatly reduced

91 Ab in hybridoma supernatants via plate-bound Ab-capture arrays, thereby easing screening.

92 average BrC light absorption at 405 nm (BrC Abs(405)) measured in the first few hours of plume evolu

93 ependent and T-independent (Type 1) Ags, but Ab responses to a multivalent T-independent (Type 2) Ag

94 blocked the nuclear import of YAP induced by Ab-induced HLA I activation in these cells and the incre

95 ablation or blocking of 4-1BBL signaling by Ab or 4-1BB-Fc alleviated the pathology of psoriasis by

96 IL-4Ralpha(-/-) mice serially with anti-CCR3 Ab or introducing a compound deficiency in CCR3 within I

97 he presence of serial dilutions of anti-CD20 Abs with Fc domains corresponding to each of the four su

98 wing treatment with the inhibitory anti-CD25 Ab PC61.

99 ls with a depleting version of the same CD25 Ab permitted CD8(+) effector T cell proliferation before

100 aive CD8 T cells with agonistic CD3 and CD28 Abs, mimicking TCR and costimulatory signals, coordinate

101 lation with agonistic anti-CD3 and anti-CD28 Abs, rendering them resistant to 4-1BB induced signaling

102 he fusion proteins elicit more focused CD4bs Ab response than prototypical gp120 Core by serological

103 liferative activity of a prototype anti-CD98 Ab, UM7F8, is due to Ab-induced membrane-associated ring

104 eing immunosuppressive, and enhancing B cell Ab responses, could reverse the immunosuppressive effect

105 nd IgG (mostly IgG1 and IgG4) anti-CD4+ cell Abs in 50% of the patients, with half of these cases tri

106 lation with anti-IgM or anti-Igkappa L chain Abs resulted in strong pCD79a and pPLCgamma2 signals, Ig

107 IFX), an immunogenic anti-TNF-alpha chimeric Ab, to heat stress.

108 d to the MARV GP the best among the chimeric Abs tested.

109 Among studied clones, Ab 5, Marouch 16, Mans 15 and Cg 2 were less influenced

110 ures and absent when using soluble or coated Abs.

111 nd full-length native heavy chain-containing Abs provided structural insights into the mechanism of b

112 In contrast, Abs against S Typhi interacted with live intact S Enteri

113 its to be bound by both CD4mc and anti-CoRBS Abs.

114 unctionalized primary or secondary Abs (DBCO-Ab) followed by fast protein size exclusion liquid chrom

115 ch could be rescued by Fc receptor-dependent Ab opsonization.

116 Both NAb titers and EIA detectable Abs are increased in patients experiencing a severe form

117 I-PhiAB6TSP) was more sensitive in detecting Ab-54149 than an antibody purified from anti- Ab-54149 E

118 ese limitations is the use of highly diluted Abs, which are produced by gradual reduction of an Ab co

119 aquaporin-4 (AQP4)-Ab-seropositive, 3 double-Ab-seronegative, 4 myelin oligodendrocyte glycoprotein (

120 and GFAP levels could identify those double-Ab-seronegative patients suitable to undergo in-depth au

121 The development of anti-drug Abs in response to biological products (BP) is a major d

122 daptive immune response leading to anti-drug Abs production.

123 Mice deficient in Fgl2 had dysregulated Ab responses at steady-state and upon immunization.

124 onsisting of repeated boosts to improve each Ab, even those belonging to less expanded lineages.

125 Eight Ab heavy-chain complementarity determining region 3 (HCD

126 ques where a low dose of TMV-NPNAx5 elicited Abs that persisted at functional levels for up to 11 mo.

127 into the underlying mechanism(s) of expanded Ab breadth elicited by a COBRA HA-based immunogen and ad

128 The potentiating anti-FH Ab is able to restore the surface regulatory function of

129 ered that flurophore-labelled antibodies (Fl-Abs) are quickly and strongly quenched by the studied GO

130 the studied GO-coated microwell, whereas Fl-Abs complexed with the respective analyte are weakly que

131 e, with many patients showing anti-flagellin Abs.

132 the feasibility of finger-prick sampling for Ab detection against SARS-CoV-2 using these assays.

133 in N and S and showed that the IgM, A, and G Ab responses against receptor-binding domain are signifi

134 These natural anti-Gal Abs can be used as an adjuvant to enhance processing of

135 express alpha-Gal epitopes and lack anti-Gal Abs.

136 and production of abundant natural anti-Gal Abs.

137 pha-Gal epitopes and secretes human anti-Gal Abs.

138 g DNA sequence data from four nuclear genes (Abd-A, EF1alpha-F1, EF1alpha-F2, and Wingless) and one m

139 dies to compare mature and inferred-germline Ab binding to envelope protein domain III of ZIKV and ot

140 enhancement, further information on germline Ab binding to ZIKV and the maturation process that gives

141 Higher Ab titers in these assays associated with more-severe di

142 human leukocyte antigen antibodies (Anti-HLA Ab) for donor-recipient matching and patient risk strati

143 in eliminating BM PCs and reducing anti-HLA Abs in chronically HLA-sensitized patients; however, Ab

144 hronically HLA-sensitized patients; however, Ab rebound was observed over several weeks to months fol

145 However, Abs that activate Fc gama receptors (FcgammaRs) and medi

146 a pan-H7, non-neutralizing, protective human Ab.

147 We computationally searched the human Ab variable gene repertoire for predicted structural hom

148 MFI (median: 5.300) compared to HLA class I Ab (median: 2.300).

149 Intestinal tissues from I-Ab(DeltaIEC) mice had a lower proportion of IgA-coated b

150 Mice with IEC-specific loss of MHCII (I-Ab(DeltaIEC) mice) developed less severe DSS- or T-cell

151 ed Rag1(-/-) mice treated with an anti-IFNAR Ab, primarily at the end of pregnancy as well as transie

152 lyses of Der p 2 in complex with IgG and IgE Abs were used to identify specific residues in the epito

153 anipulation produced significantly fewer IgE Abs to peanuts compared with control mice.

154 B cells and produced significantly fewer IgE Abs.

155 8 out of 11 MS brain donors is bound by IgG Abs.

156 lmark of MS diagnosis is the presence of IgG Abs, which appear as oligoclonal bands in the cerebrospi

157 Remarkably, IgG Abs specific for Mpro and other SARS-CoV-2 Ags can also

158 hich correlated with L. tropica specific IgG Abs.

159 Total IgG and IgM Ab levels were determined via ELISA.

160 These were mainly HLA class II Ab (81.5%).

161 HLA class II Ab show a higher MFI (median: 5.300) compared to HLA cla

162 he different clones ranging from 58 to 97 in Ab 5 and Mans 15 respectively.

163 es to identify specific residues involved in Ab binding provided the first epitope mapping of hIgE mA

164 s regulated differently and has key roles in Ab responses and protective immunity.

165 s and Nphs contributes to T cell-independent Ab responses.

166 gglutinin from influenza A to Clec9A induced Ab responses with higher avidity that more efficiently n

167 Interestingly, vaccine-induced Abs enhanced Ag presentation to MAIT cells, resulting in

168 ressing only the HIV Env V1V2 region induces Ab responses targeting the critical region in V2 associa

169 as the Ab functional capability of inducing Ab-dependent cell-mediated cytotoxicity (ADCC), compleme

170 cells, which can further differentiate into Ab-secreting plasma cells or memory B cells.

171 eased IgG switching and differentiation into Ab-secreting cells (ASC)-a finding that coincided with i

172 be independent of HIV status, sex, age, KSHV Ab titer, and KSHV-neutralizing activity.

173 knowledge, the first evidence that anti-KSHV Abs are capable of mediating ADCC responses against infe

174 NO1, alone or in combination with anti-PD-L1 Ab or ACY241, to restore anti-MM immunity, enhance MM cy

175 Combination of ENO1i and anti-PD-L1 Ab or HDAC6i ACY-241 enhances autologous MM-specific CD8

176 IgG isotype mediate effector functions like Ab-dependent cellular cytotoxicity and Ab-dependent cell

177 cult to perform, as simple measurements like Ab titer only partly correlate with protection.

178 y mild disease that may evoke relatively low Ab titers compared with patients admitted to hospitals.

179 haracterized the presence of anti-lymphocyte Abs in the whole cohort of 72 patients, as well as the A

180 were labeled with major basic protein (MBP) Ab to visualize granules and assessed by flow cytometry.

181 h any immunoassay, a portion of the measured Ab binding can be nonspecific.

182 ecreased ability of newborn cells to mediate Ab-dependent cell killing.

183 in differential regulation of TLR7-mediated Ab-forming cell (AFC) and germinal center (GC) responses

184 xploring pathogenic disease mechanisms of MG Abs.

185 lized subset of FOXP3+ T cells that modulate Ab responses.

186 4 myelin oligodendrocyte glycoprotein (MOG)-Ab-seropositive and 4 AQP4-Ab-seronegative with unknown

187 .9-86.5) of nonrelapsing children became MOG-Ab negative compared to 14.1% (95% CI = 4.7-38.3) of rel

188 and 4 AQP4-Ab-seronegative with unknown MOG-Ab-serostatus), multiple sclerosis (MS) (n=69), optic ne

189 ynamics between children and adults with MOG-Ab-associated disease (MOGAD).

190 ion rendered MuPyV resistant to a monoclonal Ab (mAb), whose specificity overlapped the endogenous an

191 r testing as HCDR3 loop chimeras on the MR78 Ab framework.

192 ed a mouse anti-murine GIPR antibody (muGIPR-Ab) that protected diet-induced obese (DIO) mice against

193 We then tested a full-length native Ab heavy chain encoding the same 17-residue-long HCDR3 l

194 decreased WNV-specific IgG and neutralizing Ab responses.

195 broad cross-reactive and cross-neutralizing Ab response against multiple H1N1 viral strains.

196 cted structural homologs of the neutralizing Ab MR78 that is specific to the receptor binding site (R

197 To better understand the neutralizing Ab response and risk of Ab-dependent enhancement, furthe

198 lis PGA were affected by a TLR6 neutralizing Ab.

199 Lack of vector-neutralizing Ab responses should facilitate booster vaccinations.

200 ts, 16 had developed SARS-CoV-2-neutralizing Abs by the time of inclusion in the study.

201 ross-reactivity of VH3-23/VK1-5 neutralizing Abs, informing precautions for protein-based vaccines de

202 and wildtype mice administered neutralizing Abs against type I IFN receptor.

203 ocused vaccine design to induce neutralizing Abs against MARV.

204 development to induce such MARV-neutralizing Abs.

205 s is the presence and titers of neutralizing Abs (NAbs) in infected people.

206 pigs generated a high titer of neutralizing Abs but poor T cell responses, whereas Aer induced power

207 to elicit germline versions of neutralizing Abs.

208 ess that gives rise to potently neutralizing Abs is needed.

209 common effector function for nonneutralizing Abs and is known to play a protective role in other herp

210 uggests a potential role for nonneutralizing Abs, which to date have been largely uninvestigated.

211 bs and dampened affinity for nonneutralizing Abs.

212 oscopy (IVM) showed increased association of Ab-opsonized Y. pestis with neutrophils in the dermis in

213 ts allowing for mastering the conjugation of Ab to AuNP and rationalizing, at the molecular level, th

214 indings may be relevant for future design of Ab-related therapies in the context of infectious diseas

215 Here, we examine the effects of Ab opsonization on Y. pestis interactions with phagocyte

216 memory generation, and robust generation of Ab-producing B cells.

217 e 1 dendritic cells can enhance induction of Ab and T cell responses.

218 icularly males, display an impaired level of Ab response compared with their younger counterparts, ye

219 ubjects, we found that both the magnitude of Ab responses to SARS-CoV-2 spike (S) and nucleoprotein a

220 lays an important role in the maintenance of Ab responses by promoting apoptosis and inhibiting necro

221 tiation that can result in the production of Ab-secreting and memory B cells.

222 and the neutralizing Ab response and risk of Ab-dependent enhancement, further information on germlin

223 Broader use of Ab-based drugs is constrained because of their high prod

224 Concentration and functionality of Abs and immune cells were assessed.

225 ry tract T cell responses but a low titer of Abs.

226 the mechanism of binding for these types of Abs.

227 The therapeutic use of Abs in cancer, autoimmunity, transplantation, and other

228 used to predict the effects of mutations on Ab binding affinity.

229 was observed when the assay was performed on Ab-modified MBs, and E. coli could be quantified in tap

230 ed, very limited information is available on Abs that broadly recognize the head domain.

231 modest effect in in vitro assays, opsonizing Ab had a dramatic effect in vivo on Y. pestis-neutrophil

232 F-alpha and anticitrullinated cyclic peptide Abs, along with terminal phalanx bone destruction.

233 able of eliciting V2-focused, polyfunctional Abs that effectively bind HIV and trigger various leukoc

234 Possible Ab-dependent enhancement will be further investigated.

235 ocytes in the NOD mouse model of T1D produce Abs directed against the neuronal type III intermediate

236 isolates making it one of the most promising Abs against HIV.

237 sults suggest that the ability of protective Abs elicited with one Salmonella serovar to engage with

238 es and circulating anticitrullinated protein Abs (ACPA), but neither the respective pathogenic roles

239 nstrated before day 12; nucleocapsid protein Abs emerged less consistently.

240 h the ability of mice to generate anti-Qbeta Ab and the presence of T cells.

241 t antitumor T cell response in an anti-Qbeta Ab-dependent manner and results in systemic antitumor T

242 ells, but only in the presence of anti-Qbeta Ab.

243 vailable methods currently used for rational Ab engineering.

244 h more-severe disease, and no cross-reactive Abs against prior betacoronavirus were found.

245 These pathogen-reactive Abs were largely directed against oligosaccharide (O)-an

246 PKalpha1 in B cells led to a weakened recall Ab response associated with a decline in the population

247 med phosphotyrosine Targeting by Recombinant Ab Pair, or pY-TRAP, for in vitro engineering of binders

248 n of Baff in either cDCs or Nphs had reduced Ab responses after NP-Ficoll immunization; thus, BAFF pr

249 After reviewing Ab-mediated immunity after coronavirus and other acute v

250 entify the efficacy of locally-delivered Scl-Ab for targeted drug delivery.

251 ivered versus low dose locally-delivered Scl-Ab via poly(lactic-co-glycolic) acid (PLGA) microspheres

252 To date, there are no studies evaluating Scl-Ab to repair osseous defects around teeth or to identify

253 Preclinical models show that Scl-Ab administration preserves bone volume during periodont

254 e (DBCO)-functionalized primary or secondary Abs (DBCO-Ab) followed by fast protein size exclusion li

255 each cells, the Ag affinity of the secreted Abs.

256 ed rates of Ig production and elevated serum Ab concentrations elicited by primary immunization.

257 genic map and serologically quantified serum Abs specific for distinct RBD epitopes leading to the id

258 of SARS-CoV-2 nucleocapsid protein-specific Ab-secreting cells in all 20 COVID-19 patients using a m

259 resently we demonstrate that the V2-specific Ab response from this regimen was highly durable and fun

260 Bs revealed that, in particular, gB-specific Abs were associated with the ADCC response.

261 Pathogen-specific Abs are typically a major predictor of protective immuni

262 mproved titer and avidity of repeat-specific Abs compared to a nearly full-length protein vaccine (FL

263 prepare the body to rapidly secrete specific Abs during an infection.

264 ed correlated this efficacy with V2-specific Abs that were effectively nonneutralizing.

265 d phagocytosis assays, we could substantiate Ab-dependent cellular phagocytosis (ADCP) and Ab-depende

266 s is a determinant of their response to such Abs.

267 Although broadly protective, stem-targeted Abs against the influenza A virus hemagglutinin (HA) hav

268 Passive transfer studies showed that Abs were sufficient for protection.

269 The Ab-NP conjugates were prepared by reacting azide-functio

270 lation of Ag-specific CD4(+) T cells and the Ab response in mice.

271 whole cohort of 72 patients, as well as the Ab functional capability of inducing Ab-dependent cell-m

272 onjugation is of critical importance, as the Ab-AuNP bioconjugates should be stable while maintaining

273 In addition, to evaluate the Ab response elicited by P1 HA at increased resolution, a

274 e only 57% amino acid sequence identity, the Ab from a MARV-naive donor recognized MARV GP and posses

275 SHM was highest in the Ab complementarity determining regions (CDRs) but also s

276 We mapped the Ab responses to different areas on protein N and S and s

277 ination, as central to the maturation of the Ab and autoantibody responses.

278 ic hypermutation (SHM) generates much of the Ab diversity necessary for affinity maturation and effec

279 rm of the disease, and in older patients the Ab titers were heightened.

280 n rectal secretions are used to evaluate the Abs elicited by HIV vaccines or the bioaccumulation foll

281 These Abs carry a unique but crucial post-translational modifi

282 This Ab could serve as a potential new drug for aHUS patients

283 However, it is unclear whether this Ab can potentiate FH mutant variants in addition to wild

284 n symptoms of a subsequent infection through Ab-dependent enhancement.

285 The ability to target survivin through Ab recognition of autoreactive cells offers the potentia

286 tion of the TNF family cytokine TL1A through Ab blocking or genetic deletion of its receptor DR3 rest

287 ne DNA repair activities that are crucial to Ab diversification.

288 f a prototype anti-CD98 Ab, UM7F8, is due to Ab-induced membrane-associated ring CH (MARCH) E3 ubiqui

289 il crawling and extravasation in response to Ab-opsonized bacteria.

290 Generally, total Ab bridging assays combine good sensitivity with high sp

291 Therefore, we developed sensitive total Ab bridging assays for detection of SARS-CoV-2 Abs to th

292 es, depending on the specificity of the used Abs.

293 normal human serum and plasma by ELISA using Abs specific for ficolin-2 and ficolin-3.

294 we engineered the model sodium channel Na(V)Ab with voltage-shifting mutations and the toxin-binding

295 ravis (MG) is an autoimmune disease in which Abs target neuromuscular junction proteins, in particula

296 Stimulation of these cells with Ab W6/32 induced marked translocation of YAP to the nucl

297 by the P1 HA Ag, with some mAbs endowed with Ab-dependent cell-mediated cytotoxicity activity.

298 tional activity in human ECs challenged with Abs that bind HLA I.

299 Protection correlated with Abs acquired transplacentally or from breastmilk that me

300 tency and whether blocking IC molecules with Abs reverses HIV latency.