ライフサイエンスコーパス: Acanthamoeba

1 otential of the facultative amoebal parasite Acanthamoeba.

2 bor dormant-resistant stages of Fusarium and Acanthamoeba.

3 tive against bacteria than fungal species or Acanthamoeba.

4 d by several free-living amebae of the genus Acanthamoeba.

5 lpha-demethylase as the target for azoles in Acanthamoeba.

6 , cloned, and characterized a novel MBP from Acanthamoeba.

7 ydrostigmasterol or any other phytosterol in Acanthamoeba.

8 oscopy are helpful for diagnosing fungus and Acanthamoeba.

9 definite fungus; kappa was 0.72 for definite Acanthamoeba.

10 the eye is uninflamed and medically cured of Acanthamoeba.

11 included in the study, 40 were positive for Acanthamoeba (10%); of these 40, 16 were positive for bo

12 ts suggest that promoter elements within the Acanthamoeba 5S RNA gene are somewhat redundant, with th

13 s hypothesized to have had insufficient anti-Acanthamoeba activity.

14 es only, which are seen in the patients with Acanthamoeba alone).

15 person with dual Balamuthia mandrillaris and Acanthamoeba amebic encephalitis with neurotoxoplasmosis

16 IV infection and Balamuthia mandrillaris and Acanthamoeba amebic encephalitis with Toxoplasma gondii

17 profiles documented the efficient uptake of Acanthamoeba amino acids into the LCV and further into L

18 Acanthamoeba amoeba in 16 solutions (80 %) collected fro

19 Nine ATCC strains of Acanthamoeba and 40 delinked, biobanked, surplus corneal

20 gal keratitis positive); 5 were positive for Acanthamoeba and bacteria; and 2 had triple infection wi

21 The largest known DNA viruses infect Acanthamoeba and belong to two markedly different famili

22 genes) determined the genotypic diversity of Acanthamoeba and found that many named species of Acanth

23 There have been epidemic increases in Acanthamoeba and fungal keratitis associated with partic

24 particular were more frequently seen in the Acanthamoeba and fungal keratitis group (8/16) and they

25 moeba and fungi (4.5% of the study group was Acanthamoeba and fungal keratitis positive); 5 were posi

26 10%); of these 40, 16 were positive for both Acanthamoeba and fungi (4.5% of the study group was Acan

27 ich might both promote the immune evasion of Acanthamoeba and limit the induced inflammatory response

28 Truncated myosins from Acanthamoeba and other model organisms have been visuali

29 cluding Megavirus, Mimivirus (both infecting acanthamoeba), and a virus infecting the marine microfla

30 lso showed that cofilins from fission yeast, Acanthamoeba, and human sever actin filaments optimally

31 luding strains of Legionella, Mycobacterium, Acanthamoeba, and Pseudomonas, are now frequently cited

32 t been observed in environmental isolates of Acanthamoeba, and their natural ecological niche is unkn

33 hamoeba and found that many named species of Acanthamoeba are associated with particular genotypes.

34 Pathogenic isolates of Acanthamoeba are medically relevant as the causative age

35 Both Fusarium and Acanthamoeba at concentrations tested above 10(3) per mL

36 completely killing 15 different isolates of Acanthamoeba at time points of 24, 48, and 72 hours in c

37 More than 20 species of Acanthamoeba belonging to morphological groups I, II, an

38 e sequencing of the mimivirus, a parasite of Acanthamoeba, blurs the boundary between viruses and cel

39 ve a specific organism present (10 fungus, 1 Acanthamoeba) but had negative results via culture and l

40 our results indicating that intoxication of Acanthamoeba by these exotoxins does not require a recep

41 red strains of genomic model taxa including: Acanthamoeba, Cafeteria, Cercomonas, Chlamydomonas, Chlo

42 Free-living amoebae of the genus Acanthamoeba can cause severe and chronic infections in

43 rse soil amoebas including Dictyostelium and Acanthamoeba can host intracellular bacteria.

44 RMIL homology 3 (CAH3) domain from mouse and Acanthamoeba CARMIL rapidly and potently restores actin

45 Acanthamoeba CARMIL was previously shown to co-purify wi

46 is and when assessing the persistent rise in Acanthamoeba cases in the United States since 2003.

47 Infection of EpiCorneal cells with Acanthamoeba castellanii 50493 and A. polyphaga 50372 le

48 decreased by nearly 3 orders of magnitude in Acanthamoeba castellanii amoebae and nearly 2 orders of

49 atest overall inhibition for all isolates of Acanthamoeba castellanii and Acanthamoeba polyphaga test

50 against two potentially pathogenic species, Acanthamoeba castellanii and Acanthamoeba polyphaga, and

51 umophila promotes intracellular infection of Acanthamoeba castellanii and Hartmannella vermiformis, t

52 cells, including macrophages and the amoebae Acanthamoeba castellanii and Hartmannella vermiformis.

53 Following encystment in Acanthamoeba castellanii and reversion of cysts to amoeb

54 ization mode in CYP51 from a human pathogen, Acanthamoeba castellanii CYP51 (AcCYP51).

55 Pathogenic mycobacteria lyse Acanthamoeba castellanii in an Esx-1-dependent manner.

56 coded Stx efficiently kills the bacteriovore Acanthamoeba castellanii in co-culture.

57 stinct hosts, the mutants were evaluated for Acanthamoeba castellanii invasion.

58 Acanthamoeba castellanii is a ubiquitous free-living amo

59 MS), we demonstrate that the major sterol of Acanthamoeba castellanii is ergosterol and identify nove

60 The opportunistic pathogen, Acanthamoeba castellanii is the causative agent for the

61 Here we report that the eukaryote Acanthamoeba castellanii lacks the G(-1) identity elemen

62 Acanthamoeba castellanii mannose-binding protein (MBP) m

63 We describe a quantitative analysis of Acanthamoeba castellanii myosin II rod domain images col

64 catalytic motor domain of the heavy chain of Acanthamoeba castellanii myosin-2 and the phosphomimetic

65 eplicated less efficiently in phytate-loaded Acanthamoeba castellanii or Dictyostelium discoideum, an

66 in this group, which is capable of infecting Acanthamoeba castellanii Pacmanvirus A23 has a linear co

67 closest homolog in Pandoraviruses and 10% in Acanthamoeba castellanii probably through horizontal gen

68 examined possible mechanisms to explain why Acanthamoeba castellanii remains restricted to the corne

69 We discovered that the enzyme target [Acanthamoeba castellanii sterol 14alpha-demethylase (AcC

70 f amino acids from the natural host organism Acanthamoeba castellanii to Legionella pneumophila under

71 Acanthamoeba castellanii were exposed to varying strengt

72 -2006 keratitis outbreak and trophozoites of Acanthamoeba castellanii were inoculated into commercial

73 legionellae for their capacity to parasitize Acanthamoeba castellanii Whereas the mutant behaved norm

74 Infection in murine macrophages, amoebae (Acanthamoeba castellanii), nematodes (Caenorhabditis ele

75 Among these, Acanthamoeba castellanii, A. polyphaga, and A. hatchetti

76 tected by certain individual assays included Acanthamoeba castellanii, Acanthamoeba culbertsoni, and

77 at five FLA species (Acanthamoeba polyphaga, Acanthamoeba castellanii, Acanthamoeba lenticulata, Verm

78 with the P450 gene products we identified in Acanthamoeba castellanii, an amoeba host for many giant

79 ir L. pneumophila growth in the amoebal host Acanthamoeba castellanii, demonstrating a host-specific

80 The animals were then infected via Acanthamoeba castellanii-laden contact lenses.

81 t phenotype (REP) in the free-living amoeba, Acanthamoeba castellanii.

82 intracellular growth in the unicellular host Acanthamoeba castellanii.

83 nea and Cbu.L1951 from lower eukaryotes like Acanthamoeba castellanii.

84 ic cell line U937 and the environmental host Acanthamoeba castellanii.

85 hamsters resistant to corneal infection with Acanthamoeba castellanii.

86 red for full virulence in the protozoan host Acanthamoeba castellanii.

87 on of antifungal drugs in the human pathogen Acanthamoeba castellanii.

88 eement with in vivo competition assays using Acanthamoeba castellannii or human macrophage-like U937

89 The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sig

90 to the putative membrane-binding domains of Acanthamoeba class I myosins.

91 inite fungus (kappa: 0.88-0.95) and definite Acanthamoeba classification (kappa: 0.63-0.90).

92 Here, we asked whether Acanthamoeba clinical isolates from non-AK infections ar

93 Acanthamoeba coinfections are much more frequent and are

94 d with Acanthamoeba keratitis, as well as in Acanthamoeba coinfections.

95 Infection is usually initiated by Acanthamoeba-contaminated contact lenses and produces ex

96 einases are responsible for the induction of Acanthamoeba CPE, led us to propose that human mucosal s

97 Acanthamoeba culbertsoni is an opportunistic pathogen th

98 al assays included Acanthamoeba castellanii, Acanthamoeba culbertsoni, and Acanthamoeba lenticulata.

99 Four clinical samples were Acanthamoeba culture negative and real-time PCR positive

100 aPA activity of Acanthamoeba cultures was quantitated by radial diffusio

101 volume of drug was inoculated with 0.1 mL of Acanthamoeba cysts (range, 1-3 x 10(6)/mL) (determined w

102 the presence or absence of fungal hyphae or Acanthamoeba cysts by the confocal microscopist who perf

103 etermining the depth of fungal filaments and acanthamoeba cysts in infectious keratitis.

104 ucibility for detecting fungal filaments and Acanthamoeba cysts in moderate to large corneal ulcers i

105 We describe here the ability of Acanthamoeba cysts to survive desiccation for more than

106 ns device was constructed and used to expose Acanthamoeba cysts to various levels of UV irradiation.

107 an average log reduction of over 3.5 log of Acanthamoeba cysts when the lens and solution inside of

108 as able to provide a marked log reduction to Acanthamoeba cysts, one of the most resistant ocular dis

109 extraction protocol enabled us to detect 0.7 Acanthamoeba cysts/10 microl and 2.3 Acanthamoeba tropho

110 monstrating that the pathogenic potential of Acanthamoeba directly correlates with the expression lev

111 eveloped for the detection of genus-specific Acanthamoeba DNA but lacked clinical validation.

112 Acanthamoeba DNA is nucleosomal with a repeat of approxi

113 s no standard in vitro test to evaluate anti-Acanthamoeba drugs.

114 We investigated the potential effect of Acanthamoeba-endosymbiont coinfection in a human corneal

115 of trophozoites of five different species of Acanthamoeba exhibiting various degrees of pathogenic po

116 r genotypic identification of 29 isolates of Acanthamoeba from non-AK infections.

117 nd bacteria; and 2 had triple infection with Acanthamoeba, fungi, and bacteria.

118 d with trophozoites of a clinical isolate of Acanthamoeba (genotype T4) or stimulated with amoeba-der

119 T2, T4, and T5 genotypes of Acanthamoeba have been identified, and T4 isolates were

120 ngal infection was detected in 176 (74%) and Acanthamoeba in 17 (7%) by microbiological methods.

121 part of an anti-predator strategy; it kills Acanthamoeba in co-culture.

122 the potential to provide protection against Acanthamoeba-induced CPE by an additional mechanism that

123 IgA-depleted milk inhibited the Acanthamoeba-induced CPE in a concentration-dependent ma

124 The antibody also inhibited the Acanthamoeba-induced CPE on host cells.

125 potential to provide protection against the Acanthamoeba-induced cytopathic effect (CPE) by an addit

126 4-, and TLR2/4-deficient mice indicated that Acanthamoeba-induced proinflammatory cytokine production

127 Accordingly, IL-17A neutralization in Acanthamoeba-infected wild-type mice or Acanthamoeba inf

128 as to gain insight into the pathogenicity of Acanthamoeba infection as well as to determine whether o

129 MBP plays a key role in the pathogenesis of Acanthamoeba infection by mediating host-parasite intera

130 mal injection-induced AK model, we show that Acanthamoeba infection induces a strong CD4(+) T effecto

131 We also demonstrate that corneal Acanthamoeba infection induces IL-17A expression and tha

132 n in Acanthamoeba-infected wild-type mice or Acanthamoeba infection of mice lacking IL-17A resulted i

133 article suggest that IL-17A production after Acanthamoeba infection plays an important role in host p

134 Dissecting the immunology of Acanthamoeba infections has been considered problematic

135 enotype T4 is the primary genotype in non-AK Acanthamoeba infections, as was the case in AK infection

136 es/macrophages are thought to be involved in Acanthamoeba infections, but little is known about how t

137 cknowledged as playing a significant role in Acanthamoeba infections, little is known about how this

138 elopment of the inflammatory response during Acanthamoeba infections.

139 We have shown that Acanthamoeba interacts with a mannosylated protein on co

140 romal keratitis were additionally tested for Acanthamoeba irrespective of the clinical diagnosis.

141 Acanthamoeba is a free-living ameba that is found throug

142 Acanthamoeba is a free-living protozoan genus found in a

143 Each Acanthamoeba isolate was used to infect EpiCorneal cells

144 Environmental and corneal Acanthamoeba isolates from the American Type Culture Col

145 08.9 +/- 812.5 cells/mm(2); P < 0.0001), and Acanthamoeba keratitis (1000.2 +/- 1090.3 cells/mm(2); P

146 Quantify and describe Acanthamoeba keratitis (AK) cases in British Columbia (B

147 Acanthamoeba keratitis (AK) is a rare but sight-threaten

148 Acanthamoeba keratitis (AK) is a very painful and vision

149 l microscopy diagnostic criteria to diagnose Acanthamoeba keratitis (AK) using polymerase chain react

150 lls, a key first step in the pathogenesis of Acanthamoeba keratitis (AK), a devastating corneal infec

151 as the causative agent of sight- threatening Acanthamoeba keratitis (AK), serious infections of other

152 tchetti are frequently identified as causing Acanthamoeba keratitis (AK).

153 ision-threatening corneal infection known as Acanthamoeba keratitis (AK).

154 ve agent for the sight threatening infection Acanthamoeba keratitis (AK).

155 Oral immunization with MIP133 mitigates Acanthamoeba keratitis and demonstrates the feasibility

156 pecifically, there has been an insurgence of Acanthamoeba keratitis and Fusarium keratitis.

157 entially with herpes simplex keratitis, then Acanthamoeba keratitis before referral.

158 (aPA) play key roles in the pathogenesis of Acanthamoeba keratitis by inducing a cytopathic effect o

159 Confirmation of Acanthamoeba keratitis by laboratory diagnosis is the fi

160 n findings can be useful for differentiating acanthamoeba keratitis from bacterial and fungal keratit

161 immune apparatus are important in preventing Acanthamoeba keratitis from progressing to become an int

162 The pathogenesis of Acanthamoeba keratitis is a complex, sequential process.

163 Acanthamoeba keratitis is a debilitating eye disease tha

164 Acanthamoeba keratitis is a serious vision-threatening d

165 Acanthamoeba keratitis is a sight-threatening infection

166 Here we show that Acanthamoeba keratitis is profoundly affected by mannosy

167 s are among the most ubiquitous amoebae, yet Acanthamoeba keratitis is remarkably rare.

168 The unexplained persistence of the Acanthamoeba keratitis outbreak in the United States, cl

169 or for case contamination among Fusarium and Acanthamoeba keratitis patients.

170 tis, and 115 patients with laboratory-proven acanthamoeba keratitis seen at Aravind Eye Hospital, Mad

171 ifferentiating features were more common for acanthamoeba keratitis than for bacterial or fungal kera

172 tex beads induces a remarkable resistance to Acanthamoeba keratitis that is largely, if not entirely,

173 oscopy could be useful in cases of fungal or acanthamoeba keratitis to determine the depth of infecti

174 Acanthamoeba keratitis was defined as the presence of AK

175 Acanthamoeba keratitis was diagnosed on microbiological

176 bacterial or fungal keratitis, patients with acanthamoeba keratitis were more likely to be younger an

177 s adverse events, particularly bacterial and Acanthamoeba keratitis while using these lenses, althoug

178 with fungal keratitis, and 93 patients with acanthamoeba keratitis who had medical records available

179 dies reporting resolution or modification of Acanthamoeba keratitis without specific antiacanthamoeba

180 Acanthamoeba keratitis, a rare eye disease primarily aff

181 The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sight-threatening infec

182 stromal edema are frequently associated with Acanthamoeba keratitis, as well as in Acanthamoeba coinf

183 ial keratitis, epithelial regeneration line, Acanthamoeba keratitis, mucus plaque keratopathy, medica

184 his may provide new treatment modalities for Acanthamoeba keratitis.

185 reen new anti-infectives in the treatment of Acanthamoeba keratitis.

186 ould test the validity of this treatment for Acanthamoeba keratitis.

187 corneal scrapings from bacterial, viral, or Acanthamoeba keratitis.

188 a) inhibitors may be a therapeutic target in Acanthamoeba keratitis.

189 al-time PCR assays could be used to diagnose Acanthamoeba keratitis.

190 P-133 produce an additive protection against Acanthamoeba keratitis.

191 ubsequent steps of the pathogenic cascade of Acanthamoeba keratitis.

192 hat mediate latex bead-induced resistance to Acanthamoeba keratitis.

193 astellanii antigens fails to protect against Acanthamoeba keratitis.

194 innate immune apparatus in the resistance to Acanthamoeba keratitis.

195 ils in latex-bead-induced protection against Acanthamoeba keratitis.

196 ge amounts of mannose and is associated with Acanthamoeba keratitis.

197 o chlorhexidine, a drug widely used to treat Acanthamoeba keratitis.

198 4 patients underwent diagnostic testing for Acanthamoeba keratitis.

199 a, such as herpes simplex virus keratitis or Acanthamoeba keratitis.

200 Gel filtration experiments revealed that the Acanthamoeba lectin is a approximately 400-kDa protein t

201 hamoeba polyphaga, Acanthamoeba castellanii, Acanthamoeba lenticulata, Vermamoeba vermiformis and Dic

202 a castellanii, Acanthamoeba culbertsoni, and Acanthamoeba lenticulata.

203 In summary, we have characterized Acanthamoeba MBP and have shown that it is a major virul

204 (ii). polyclonal antibodies prepared against Acanthamoeba MBP bound to the recombinant protein.

205 nd sequencing experiments indicated that the Acanthamoeba MBP gene is composed of 6 exons and 5 intro

206 tion with our published studies showing that Acanthamoeba MBP is a major virulence protein suggest th

207 However, direct evidence showing that Acanthamoeba MBP is a virulence protein has been lacking

208 ith high affinity for mannose, revealed that Acanthamoeba MBP is itself a mannose-containing glycopro

209 aining, it was conclusively established that Acanthamoeba MBP is located on the surface membranes of

210 Hexosamine analysis revealed that Acanthamoeba MBP lacks detectable levels of GalNAc, sugg

211 ntibodies prepared against affinity-purified Acanthamoeba MBP markedly inhibit the adhesion of parasi

212 The most striking feature of the Acanthamoeba MBP sequence is the presence of a cysteine-

213 here the isolation and molecular cloning of Acanthamoeba MBP.

214 Acanthamoeba move directionally in a three-dimensional (

215 The 466-aa tail of the heavy chain of Acanthamoeba myosin IC (AMIC) comprises an N-terminal 22

216 The tail of Acanthamoeba myosin IC (AMIC) has a basic region (BR), w

217 Previously, we found that Acanthamoeba myosin IC binds to acidic phospholipids in

218 Acanthamoeba myosin II (AMII) has two heavy chains endin

219 ed previously that only filamentous forms of Acanthamoeba myosin II have actin-activated MgATPase act

220 al, we show that two nonfilamentous forms of Acanthamoeba myosin II, heavy meromyosin and myosin subf

221 Acanthamoeba myosin-II forms bipolar octamers by three s

222 ggest that the first step in the assembly of Acanthamoeba myosin-II is anti-parallel dimerization of

223 uncation constructs and point mutants of the Acanthamoeba myosin-II tail to delineate the structural

224 ute bacterial (n = 23), fungal (n = 13), and Acanthamoeba (n = 17) keratitis, and in 20 normal eyes,

225 nosis of bacterial (n=28), fungal (n=15), or Acanthamoeba (n=13) keratitis were included in the study

226 pes simplex virus, n = 16; bacteria, n = 10; Acanthamoeba, n = 5), with healthy endothelium.

227 ebae reproduce sexually, many amoebae (e.g., Acanthamoeba, Naegleria) reproduce asexually and therefo

228 Mature cysts of Acanthamoeba not evident in the inocula were observed in

229 this work was to investigate the effects of Acanthamoeba on human monocytes/macrophages during the e

230 in this study we investigated the effects of Acanthamoeba on the activation of resting macrophages.

231 iral, or immune keratitis featuring negative Acanthamoeba PCR results (control group).

232 ose-induced cytopathic protein (MIP-133) and Acanthamoeba plasminogen activator (aPA) play key roles

233 e simultaneous discovery of a giant virus of Acanthamoeba polyphaga (Lentille virus) that contains an

234 ated to Mycobacterium spp. was identified in Acanthamoeba polyphaga 50495.

235 We cultured, on Acanthamoeba polyphaga amoebae, pulmonary samples from 1

236 who failed to mount a serologic response to Acanthamoeba polyphaga is presented.

237 The genome sequence of the giant virus Acanthamoeba polyphaga mimivirus revealed the presence o

238 all isolates of Acanthamoeba castellanii and Acanthamoeba polyphaga tested.

239 Although Acanthamoeba polyphaga that is sensitive to multiple ant

240 uster resulted in virulence towards amoebae (Acanthamoeba polyphaga) and reduced colonization of plan

241 Here, we show that five FLA species (Acanthamoeba polyphaga, Acanthamoeba castellanii, Acanth

242 ogenic species, Acanthamoeba castellanii and Acanthamoeba polyphaga, and has been validated by compar

243 ular proliferation within human macrophages, Acanthamoeba polyphaga, and the ciliate Tetrahymena pyri

244 h three FLA, namely, Vermamoeba vermiformis, Acanthamoeba polyphaga, and Willaertia magna, we followe

245 Mimivirus, a parasite of Acanthamoeba polyphaga, is the largest DNA virus known;

246 ed macrophages (hMDMs), U937 macrophages and Acanthamoeba polyphaga.

247 ithin human monocyte-derived macrophages and Acanthamoeba polyphaga.

248 r up to 8 h postinfection of macrophages and Acanthamoeba polyphaga.

249 ins produced by bacteria internalized by the Acanthamoeba predator are cytolethal; the presence of pu

250 ages cocultured with the clinical isolate of Acanthamoeba produced significantly less IL-12 and IL-6

251 complete description of sterol metabolism in Acanthamoeba, provide a putative framework for their fur

252 Acanthamoeba sclerokeratitis is associated with poor cli

253 or a chicken monoclonal antibody against the Acanthamoeba serine protease MIP-133.

254 with MIP-133 before and after infection with Acanthamoeba significantly reduced the severity of corne

255 s two parasites (Balamuthia mandrillaris and Acanthamoeba), six bacterial pathogens (Streptococcus pn

256 nation showed fungi or cysts consistent with Acanthamoeba sp.).

257 ed fibrils surrounding their capsids, infect Acanthamoeba sp., which are ubiquitous unicellular eukar

258 Acanthamoeba species are among the most ubiquitous amoeb

259 Acanthamoeba species are infected by the largest known D

260 Acanthamoeba species can cause keratitis, a painful visi

261 Two different strains of Acanthamoeba species were tested identically.

262 Pathogenic free-living amoebae, such as Acanthamoeba species, Balamuthia mandrillaris, and Naegl

263 A virus identified so far, infecting several Acanthamoeba species.

264 more effective than edelfosine against both Acanthamoeba species.

265 es of much needed new antimicrobials against Acanthamoeba species.

266 ns wearers, is caused by free-living amebae, Acanthamoeba species.

267 It is thought that Acanthamoeba-specific IgA antibodies present in mucosal

268 d in pathogenic and nonpathogenic strains of Acanthamoeba spp.

269 ocyte-derived macrophages (hMDMs) but not in Acanthamoeba spp.

270 nt nucleotide identity with endosymbionts of Acanthamoeba spp. (order Chlamydiales).

271 lla and mycobacteria), and two amoeba hosts (Acanthamoeba spp. and Hartmanella vermiformis).

272 he, but is dispensable for growth within the Acanthamoeba spp. that synthesize the aromatic amino aci

273 um intracellulare, Pseudmonas aeruginosa, or Acanthamoeba spp.) during the entire course of the study

274 Of the isolated amoebae, 31 were Acanthamoeba spp., 21 were Hartmannella vermiformis, 13

275 tions of Legionella spp., M. intracellulare, Acanthamoeba spp., and M. avium peaked during the dry se

276 e-living amoebae, such as Naegleria fowleri, Acanthamoeba spp., and Vermamoeba spp., have been identi

277 more, we demonstrate for the first time that Acanthamoeba stimulates IL-10 production in human innate

278 annot achieve eradication in the 2 different Acanthamoeba strains examined.

279 Both Acanthamoeba strains induced a proinflammatory macrophag

280 Acanthamoeba strains that bound avidly to host cells and

281 f Legionella, reduction in P. aeruginosa and Acanthamoeba) suggest a temporally dynamic drinking wate

282 ATCC and clinical strains of Acanthamoeba that failed to be detected by certain indiv

283 For Acanthamoeba, the pooled sensitivity was 88.2% (95% CI:

284 his assay may be helpful for guiding topical Acanthamoeba therapy and providing a practical method to

285 Acanthamoeba trophozoite migration is also voltage-depen

286 method for determining the susceptibility of Acanthamoeba trophozoites and cysts to contact lens care

287 We showed that both Acanthamoeba trophozoites and soluble amoebic products i

288 ig corneas and was used to determine whether Acanthamoeba trophozoites could penetrate this membrane

289 Acanthamoeba trophozoites move at random in the absence

290 Acanthamoeba trophozoites move directionally in response

291 We investigated the in vitro response of Acanthamoeba trophozoites to electric fields (EFs).

292 ation in a three-dimensional culture system, Acanthamoeba trophozoites were cultured in agar, exposed

293 phages in the recognition of and response to Acanthamoeba trophozoites.

294 ect 0.7 Acanthamoeba cysts/10 microl and 2.3 Acanthamoeba trophozoites/10 microl by both real-time PC

295 a found in drinking water networks, that is, Acanthamoeba, Vermamoeba, Echinamoeba, and Protacanthamo

296 ia-like endosymbiont has previously enhanced Acanthamoeba virulence in vitro.

297 lasses of bacterial endosymbionts attenuated Acanthamoeba virulence, as indicated by decreased observ

298 Acanthamoeba was the most frequent microbe (10/17; 59%),

299 of 3 well-characterized clinical strains of Acanthamoeba were exposed at 0.5, 2.0, 3.5, 5.0, and 6.5

300 f trophozoites of four different isolates of Acanthamoeba with various degrees of in vitro pathogenic