ライフサイエンスコーパス: African green monkey

1 zed but estrogen-replaced nonhuman primates (African green monkeys).

2 SFV serotype 3 (SFVagm-3), isolated from an African green monkey.

3 cur among natural SIV variants isolated from African green monkeys.

4 animal model of lymphatic obstruction using African green monkeys.

5 to dietary cholesterol, and less responsive African green monkeys.

6 V-1 and simian immunodeficiency viruses from African green monkeys.

7 from vervet, grivet, and tantalus species of African green monkeys.

8 oost neutralization titers in RSV-preexposed African green monkeys.

9 ts implanted in the striatum of MPTP-treated African green monkeys.

10 ulated in the dorsal and ventral striatum of African green monkeys.

11 vaccine candidates after a single passage in African green monkeys.

12 elae of SARS-CoV-2 using SARS-CoV-2 infected African green monkeys.

13 increased suPAR levels and glomerulopathy in African green monkeys.

14 igtail macaques, rhesus macaques, and vervet African green monkeys.

15 simian immunodeficiency virus infections of African Green Monkeys.

16 tion in both LDL receptor-deficient mice and African green monkeys.

17 DSS treatment of SIV-infected African green monkeys, a natural host species for SIV th

18 l administration to the respiratory tract of African green monkeys, a permissive primate host.

19 luding human A3C (hA3C), human A3DE (hA3DE), African green monkey A3F (agmA3F), and rhesus macaque A3

20 irus (SIV) Vif was shown to bind and degrade African green monkey A3G (agmA3G) and, unexpectedly, hum

21 Here, we report the DNA sequence of an African green monkey AAV integration site isolated from

22 G but not rhesus macaque APOBEC3G (rhA3G) or African green monkey (AGM) APOBEC3G (agmA3G) because of

23 veloped for studying HeV infection, with the African green monkey (AGM) appearing to most faithfully

24 Currently, the African green monkey (AGM) best mimics human henipavirus

25 The present report reveals that African green monkey (AGM) cells, which contain extensiv

26 l block within human cells that is absent in African green monkey (AGM) cells.

27 man APOBEC3G but does not block the mouse or African green monkey (AGM) enzyme.

28 , we examined the pathogenesis of HeV in the African green monkey (AGM) following intratracheal inocu

29 e, preclinical studies were conducted in the African green monkey (AGM) inhalational model of pneumon

30 Here, an African green monkey (AGM) model was used to elucidate i

31 ddress this issue, we established a neonatal African green monkey (AGM) nonhuman primate model that c

32 PIV5)-vectored COVID-19 vaccine CVXGA1 in an African green monkey (AGM) nonhuman primate model.

33 Conversely, the Vif protein encoded by the African green monkey (agm) simian immunodeficiency virus

34 amics of the A3G-Vif interaction within four African green monkey (AGM) subspecies, which are each na

35 ort of endogenous retroviruses produced from African green monkey (AGM) tissues or cell lines.

36 is achieved by comparing a natural SIV host, African green monkey (AGM) to an AIDS susceptible specie

37 function, we isolated cDNA clones of human, African green monkey (AGM), and NIH/Swiss mouse CCR5s, a

38 In a natural host of SIV, the African green monkey (AGM), NK cells mediate a strong co

39 of SIVsab from its natural host, the sabaeus African green monkey (AGM), to a new host, the pigtailed

40 To investigate replication in primates, African green monkeys (AGM) and rhesus macaques (n = 4)

41 African green monkeys (AGM) and sooty mangabeys (SM) are

42 Natural hosts, such as African green monkeys (AGM) and sooty mangabeys (SM), ar

43 SIV) infection in its natural hosts, such as African green monkeys (AGM) and sooty mangabeys (SM).

44 African green monkeys (AGM) are natural hosts of simian

45 African green monkeys (AGM) are natural hosts of SIV, an

46 African green monkeys (AGM) do not develop overt signs o

47 d plasma were assessed in naturally infected African green monkeys (AGM) of the vervet subspecies (Ch

48 In contrast, both marmosets and African green monkeys (AGM) proved susceptible to aeroso

49 te pathogenic differences between strains, 4 African green monkeys (AGM) were exposed to NiVM and 4 A

50 onprogressive infection (SIVagm infection of African green monkeys (AGM)), and transient, controlled

51 ch as chimpanzees, sooty mangabeys (SM), and African green monkeys (AGM).

52 a wide range of African primates, including African green monkeys (AGM).

53 with AddaVax to elicit responses in newborn African green monkeys (AGM).

54 RDV administered by head dome inhalation in African green monkeys (AGM).

55 inistered within 2-6 hours of fever onset in African green monkeys (AGM).

56 HIV-2 (EHO and ALI), and one strain of SIV (African Green Monkey, AGM).

57 their virulence in BALB/c mice, ferrets, and African green monkeys (AGMs) (Chlorocebus aethiops).

58 three viral pathogens in two populations of African green monkeys (AGMs) (Chlorocebus sabaeus) from

59 A model was developed in African green monkeys (AGMs) after challenge with a leth

60 e employ such approach to compare T cells of African green monkeys (AGMs) and rhesus macaques (RMs).

61 (PTMs) and in nonpathogenic SIV infection of African green monkeys (AGMs) and sooty mangabeys.

62 African green monkeys (AGMs) are a natural host of SIV t

63 lar, the geographically dispersed species of African green monkeys (AGMs) are all infected with highl

64 African green monkeys (AGMs) are natural hosts of simian

65 African green monkeys (AGMs) are natural primate hosts o

66 African green monkeys (AGMs) are naturally infected with

67 African green monkeys (AGMs) are naturally infected with

68 We used African green monkeys (AGMs) as a nonhuman primate (NHP)

69 reflect the findings in humans and evaluated African green monkeys (AGMs) as a nonhuman primate model

70 ous (approximately 98-99% identical) CCR5 of African green monkeys (AGMs) avidly binds beta-chemokine

71 To test the hypothesis that SIV-infected African green monkeys (AGMs) avoid AIDS due to virus rep

72 rison with m102.4 for the ability to protect African green monkeys (AGMs) from a stringent NiV challe

73 Chronically SIVagm-infected African green monkeys (AGMs) have a remarkably stable no

74 ble of eliciting a strong immune response in African green monkeys (AGMs) in a single dose.

75 We report two cases of ARDS in two aged African green monkeys (AGMs) infected with SARS-CoV-2 th

76 c SIV infection in sooty mangabeys (SMs) and African green monkeys (AGMs) is associated with low leve

77 rability of rVSV-DeltaG-NiVBG, we vaccinated African green monkeys (AGMs) one year before challenge w

78 Chronically SIV-infected African Green Monkeys (AGMs) partially recover mucosal C

79 partments of chronically SIV-infected sabeus African green monkeys (AGMs) revealed that gastrointesti

80 We show that African green monkeys (AGMs) support robust SARS-CoV-2 r

81 collected from pigtailed macaques (PTMs) and African green monkeys (AGMs) that experience different S

82 ansmitted SIVsab from the sabaeus species of African green monkeys (AGMs) to pigtailed macaques (PTMs

83 ial of NiV delivered by the aerosol route in African green monkeys (AGMs) used the Malaysia strain (N

84 A group of 10 rhesus macaques (RMs) and 10 African green monkeys (AGMs) was exposed to aerosolized

85 Caribbean-born African green monkeys (AGMs) were classified as Chloroce

86 hoid organs from chronically SIVagm-infected African green monkeys (AGMs) were frequently CXCR5(+) an

87 A small number of African green monkeys (AGMs) were introduced into the Ca

88 ation in the respiratory tracts of hamsters, African green monkeys (AGMs), and chimpanzees.

89 cted predominantly in sooty mangabeys (SMs), African green monkeys (AGMs), and mandrills.

90 cted predominantly in sooty mangabeys (SMs), African green monkeys (AGMs), and mandrills.

91 African green monkeys (AGMs), Chlorocebus pygerythrus, a

92 by simian immunodeficiency virus SIVagm from African green monkeys (AGMs), do not encode Vpu.

93 In African green monkeys (AGMs), rHPIV1-P(C-) was considera

94 immunodeficiency virus (SIV) hosts, such as African green monkeys (AGMs), sustain nonpathogenic SIV

95 Unlike HIV-1-infected humans, African green monkeys (AGMs), the natural SIV host speci

96 nfected and uninfected natural hosts of SIV, African green monkeys (AGMs), to that of RMs.

97 nsitive and attenuated in mice, ferrets, and African green monkeys (AGMs).

98 e of acute and chronic SIVagm replication in African green monkeys (AGMs).

99 The candidate vaccine was used to vaccinate African green monkeys (AGMs).

100 er several days, in the respiratory tract of African green monkeys (AGMs).

101 ne strains were tested for immunogenicity in African green monkeys (AGMs).

102 ne treatment on lung CYP2A protein levels in African green monkeys (AGMs).

103 beta induction and replicated efficiently in African green monkeys (AGMs).

104 African green monkeys (AGMs; genus Chlorocebus) are a na

105 ailed macaques [PTMs]) and nonpathogenic (in African green monkeys [AGMs]) SIVsab infections to asses

106 OROV also replicated in sabeus African green monkey, albeit at lower levels than other

107 m neutralizing antibody titers obtained from African green monkeys and after human vaccination and na

108 we demonstrate that nonhuman primates (NHPs; African green monkeys and cynomolgus macaques) harbor se

109 We identified multiple SAMHD1 haplotypes in African Green Monkeys and find that the vpr gene from di

110 ral SIV hosts (for example, sooty mangabeys, African green monkeys and mandrills) share many features

111 rence was used to disrupt CypA in cells from African green monkeys and rhesus macaques.

112 rated fats and cholesterol to nonpathogenic (African green monkeys) and pathogenic (pigtailed macaque

113 As the outcomes of SIVsab infection in PTMs, African green monkeys, and rhesus macaques are different

114 ost efficiently in the respiratory tracts of African green monkeys, and the infected animals develope

115 in the TRIM5alpha B30.2 domain v1 region of African green monkeys are also associated with broader a

116 pathogenic infections in natural hosts, such African green monkeys, are characterized by a lack of gu

117 unodeficiency virus (SIVagm) Vif can inhibit African green monkey but not human Apo3G.

118 A] were administered separately to groups of African green monkeys by the intranasal/intratracheal ro

119 African green monkeys can maintain long-term persistent

120 Similar results were observed in the African green monkey cell line COS7.

121 estricting activities expressed by human and African green monkey cell lines.

122 r molecule directed secretion of both Ags in African green monkey cells and functioned as an adjuvant

123 V(SYK) Vpr proteins are capable of arresting African green monkey cells but are completely inactive i

124 HuTRS1 (RhTRS1) fulfills these functions in African green monkey cells, but not rhesus or human cell

125 In African green monkey cells, HIV-1 virus-like particles a

126 IgA did not inhibit HAV infection of African green monkey cells, suggesting that the IgA and

127 CypA soon after entry into rhesus macaque or African green monkey cells, where, paradoxically, the in

128 attenuate Lv1 activity in rhesus macaque and African green monkey cells.

129 st activity could be demonstrated in cognate African green monkey cells.

130 African green monkeys (Cercopithecus aethiops sabaeus) w

131 Four African green monkeys (Cercopithecus aethiops) were inje

132 Herein we report that two species of African green monkeys (Chlorocebus sabaeus and C. pygery

133 0 lymphocyte-depleting antibodies to sabaeus African green monkeys (Chlorocebus sabaeus) before chall

134 ke gammaherpesviruses recently identified in African green monkeys, Chlorocebus rhadinovirus types 1

135 An African green monkey CMV UL32 homolog complemented Delta

136 exhibited a range of restriction in mice and African green monkeys comparable with that of two attenu

137 gene induction in LNCaP cells as well as in African green monkey CV-1 cells.

138 Infection of African green monkey CV1 cells with SV40 resulted in the

139 1-NTP, and in vivo studies in cynomolgus and African Green monkeys demonstrated a >10-fold higher lun

140 IVcpz [from chimpanzees] and SIVagmSab [from African green monkeys]) discordantly in different region

141 ha variants from humans, rhesus monkeys, and African green monkeys displayed different but overlappin

142 Here we show that many CD4(+) T cells from African green monkeys downregulate CD4 in vivo as they e

143 We have collected the brains of African green monkeys during multiple Nipah virus, Bangl

144 nary artery atherosclerosis were examined in African green monkeys fed diets containing cholesterol a

145 We immunised eight African green monkeys, four with a single dose of BHPIV3

146 residue 128, previously shown to distinguish African green monkey from human APOBEC3G.

147 reviously shown that intranasal SV protected African green monkeys from challenge with the related hu

148 cellular and humoral immunity that protects African green monkeys from SARS-CoV-2 challenge.

149 arteriviruses (family Arteriviridae) in wild African green monkeys from Zambia (malbroucks [Chloroceb

150 Here, we discover two new viruses in African green monkeys from Zambia and South Africa.

151 African green monkeys (genus Chlorocebus) can be infecte

152 In African green monkeys immunized intranasally and intratr

153 African green monkeys immunized through the respiratory

154 African green monkeys immunized with b/h PIV3 expressing

155 We evaluated the immunological responses of African green monkeys immunized with multiple F and G pr

156 African green monkeys immunized with two doses of the ve

157 NDV-HA was administered to African green monkeys in two doses of 2 x 10(7) infectio

158 The lesions seen in the brain of African green monkeys infected with Nipah virus, Banglad

159 ttenuated/nonprogressive infection) and from African green monkeys infected with SIVsab9315BR (nonpat

160 o strong SARS-CoV-2 antiviral efficacy in an African green monkey infection model.

161 We compared African green monkeys inoculated with infectious SARS-Co

162 r the onset of clinical anthrax disease, the African green monkey is a suitable animal model exhibiti

163 transgene expression (~2 log orders) for the African green monkey isolate AAV4.

164 two attenuated viruses adapted to growth in African green monkey kidney (AGMK) and MRC-5 cells, resp

165 unknown natural function which serves as an African green monkey kidney (AGMK) cell receptor for HAV

166 Serum-starved primary African green monkey kidney (AGMK) cells also showed dec

167 clonal antibodies raised against susceptible African green monkey kidney (AGMK) cells as probes.

168 s isolated from a cDNA expression library of African green monkey kidney (AGMK) cells by using protec

169 Hepatitis A virus (HAV) infects African green monkey kidney (AGMK) cells via the HAV cel

170 V cellular receptor 1 (havcr-1) and protects African green monkey kidney (AGMK) clone GL37 cells (GL3

171 To characterize interactions between African green monkey kidney (BS-C-1) cell proteins and t

172 (HAV), HM175/P16, enhance growth in cultured African green monkey kidney (BS-C-1) cells but not in fe

173 Lytic infection of African green monkey kidney (CV-1) cells by simian virus

174 ase cDNA and establishing stably transfected African green monkey kidney (CV1) cell lines expressing

175 We found that the infection of African green monkey kidney (Vero) cells by vesicular st

176 ed cells, and produced very small plaques on African green monkey kidney (Vero) cells that were simil

177 s, including porcine kidney (PK15) cells and African green monkey kidney (Vero) cells, was inhibited

178 H1N1, H3N2, H5N1 and H7N9 vaccine viruses in African green monkey kidney and Madin-Darby canine kidne

179 mma, inhibited vaccinia virus replication in African green monkey kidney BSC-40 cells.

180 xpansions and deletions were monitored in an African green monkey kidney cell culture system (COS-7 c

181 Preliminary studies indicated that an African green monkey kidney cell line (Vero) is a suitab

182 an lung epithelial cell line (Calu-3) and an African green monkey kidney cell line (Vero-E6).

183 ed viral rescue and growth properties in the African green monkey kidney cell line, Vero.

184 he virus within a few cycles of infection in African green monkey kidney cell lines CV-1, CV-1P, TC-7

185 process generates H2O2, was introduced into African green monkey kidney cells (CV-1 cells) under the

186 ges in cell homeostasis were investigated in African green monkey kidney cells (CV-1) by assessing th

187 ytes, Kv1.3, was heterologously expressed in African Green Monkey kidney cells (CV-1) using a vaccini

188 AM, human U937 cells (histiocytic lymphoma), African green monkey kidney cells (MARC-145 and Vero), p

189 fectivity of HSV-1 derived from immortalized African green monkey kidney cells (Vero), immortalized h

190 omes were microsurgically removed from BSC-1 African green monkey kidney cells before the completion

191 African green monkey kidney cells expressing pIgR demons

192 Hepatitis A virus (HAV) infects African green monkey kidney cells via HAV cellular recep

193 us following passage in C6/36 cells, primary African green monkey kidney cells, or Vero cells.

194 African green monkey kidney cells, Vero C1008, polarizab

195 urine melanoma cell line but not to the CV-1 African green monkey kidney cells, which express CD44 at

196 cap-independent viral translation in vivo in African green monkey kidney cells.

197 gly present in SARS-CoV-2-infected controls (African green monkey kidney clone E6 [Vero E6] cultures)

198 toma c37 cells and CYP1A1- and AHR-deficient African green monkey kidney CV-1 cells.

199 ty of their respective intracellular niches, African green monkey kidney epithelial (Vero) cells, A/J

200 inoculation was detected in only six: three African green monkey kidney epithelial cell lines (Vero,

201 ibit SV40 DNA replication in infected BSC-1 (African green monkey kidney epithelial) cells, albeit at

202 sseriae interact with CD66a-transfected COS (African green monkey kidney) and CHO (Chinese hamster ov

203 COS7 (African Green Monkey kidney) cells stably transfected wi

204 Using COS (African green monkey kidney) cells transfected with cDNA

205 Vero cells, which were derived from the African green monkey kidney, represent one of the few ma

206 lly active in 293T (embryonic kidney), Vero (African-green monkey kidney epithelial), 3T12 (mouse fib

207 These data demonstrate that African green monkey-like natural killer cell differenti

208 rimate ACAT2 gene product was cloned from an African green monkey liver cDNA library.

209 four different species of naturally infected African green monkeys living in different regions across

210 V-1 cDNA, complete suppression of macaque or African green monkey Lv1 was achieved by the additive ef

211 eceptor CXCR6 by SIVagmSab to infect sabaeus African green monkey lymphocytes.

212 ecies of natural SIV hosts (sooty mangabeys, African green monkeys, mandrills, sun-tailed monkeys, an

213 Eleven fetal African green monkey midbrains were immunostained for ty

214 Together, these data suggest that the African green monkey model exhibits important similariti

215 irol 98:e01693-23, 2024, ) in an established African green monkey model of disease.

216 validated the use of RSV (Memphis 37) in an African green monkey model of intranasal infection and i

217 or G (PIV5/G) protein in the cotton rat and African green monkey models for their replication, immun

218 Adult African green monkeys naturally have low numbers of CD4

219 The recombinant viruses were administered to African green monkeys (NDV-BC and NDV-LS) and rhesus mon

220 The infecting SFV originated from an African green monkey (one person) and baboons (three peo

221 African green monkeys, one natural host species, avoid s

222 We describe a genome reference of the African green monkey or vervet (Chlorocebus aethiops).

223 ll samples from a human infected with SFV of African green monkey origin (SFV-3).

224 xpression of endogenous CRF1 in COS-7 cells (African green monkey origin).

225 sphorylation, RhTRS1 binds to phosphorylated African green monkey PKR.

226 irus has adapted to the polymorphisms of the African Green Monkey population in which it is found.

227 T) was characterized in plasma from infected African Green monkeys, rabbits, and guinea pigs.

228 Hamsters and African green monkeys received a primary intranasal infe

229 transfection and deletion analysis in BSC-1 (African green monkey, renal epithelial) cells revealed t

230 Finally, in African green monkeys, renal cortical NOS1B expression i

231 primary cells or established cell lines from African green monkey, rhesus macaque, and baboon.

232 hepatitis after intravenous inoculation into African green monkeys, rhesus monkeys, and marmosets.

233 In an African green monkey RSV infection model, once-daily ora

234 daily 10 mg/kg IV administration of 1 in an African Green monkey RSV model demonstrated a >2-log(10)

235 proteins; the human and, to a low level, the African green monkey sequences bound soluble HCV E2 (sE2

236 most cleavage-efficient mutant, R-R-R-R, in African green monkeys showed that there was no detectabl

237 We now report a novel function of African green monkey simian immunodeficiency virus (SIVa

238 n target only human Apo3G (hApo3G), whereas, African green monkey simian immunodeficiency virus (SIVa

239 Both Vif proteins of HIV-1 and African green monkey simian immunodeficiency virus (SIVa

240 bey (simian immunodeficiency virus SIV(SM)), African green monkey (SIV(AGM)), and Sykes' monkey (SIV(

241 imian immunodeficiency viruses isolated from African green monkeys (SIVagm) contain a single accessor

242 an immunodeficiency virus (SIV) that infects African green monkeys (SIVagm) contains a vpr homologue,

243 Simian immunodeficiency virus from African green monkeys (SIVagm) results in asymptomatic i

244 during nonpathogenic infection with SIV from African green monkeys (SIVagm), follicles remain general

245 HIV-2 and simian immunodeficiency virus from African green monkeys (SIVagm), in one round of viral re

246 , which infects rhesus macaques (SIVmac) and African green monkeys (SIVagm).

247 (HIV-1) and simian immunodeficiency virus of African green monkeys (SIVagm).

248 of HIV-1 itself, HIV-2 and SIV isolated from African green monkeys (SIVAGM).

249 an HIV-1 (simian immunodeficiency virus from African green monkeys [SIVagm] and Rhesus macaques [SIVm

250 estricted infection by SIVmac and the SIV of African green monkeys, SIVagm.

251 he red-capped mangabey (SIVrcm), the sabaeus African green monkey (SIVagmSAB), and the chimpanzee (SI

252 an immunodeficiency virus (SIV) that infects African green monkeys (SIVagmTAN), unlike human Apobec3D

253 gm infection in its sabaeus monkey host, the African green monkey species endemic to West Africa.

254 r HT) gene into a demyelinated lesion of the African green monkey spinal cord.

255 assays developed to measure SIVagm from two African green monkey subspecies demonstrated high levels

256 correlated with that previously observed for African green monkeys, suggesting that the HAE model has

257 African green monkeys systemically immunized with HPV-11

258 on the CD4(+) T cells of young mandrills and African green monkeys than on those of adults, we propos

259 boost RSV neutralization antibody titers in African green monkeys that had been infected previously.

260 In African green monkeys that received a primary infection

261 Here we show in African green monkeys that systemic delivery of an anti-

262 e enzyme activities were measured in rat and African green monkey tissues.

263 model for NiV infection, we exposed 6 adult African green monkeys to a large-particle (approximately

264 In this study, we exposed African green monkeys to B. anthracis spores; examined c

265 Here, we compared the plasma virome of West African green monkeys to that in their descendants after

266 Sixteen St. Kitts African green monkeys treated with 1-methyl-4-phenyl-1,2

267 Previously, we have shown that African green monkey TRIM5alpha (AgmTRIM5alpha) potently

268 We created a panel of African green monkey TRIM5alpha (TRIM5alpha(AGM)) mutant

269 by at least two different retroviruses, and African green monkey TRIM5alpha was able to inhibit infe

270 Adult female African green monkeys underwent right C5/6 lateral hemis

271 In African green monkeys, vaccine-induced serum and mucosal

272 ls and human foreskin fibroblasts but not in African green monkey (Vero) cells.

273 A wild-type virus (using African green monkey VeroE6 cells), a pseudovirus (using

274 It was found that all vaccinated African green monkeys were completely protected against

275 HMPV-infected chimpanzees and African green monkeys were highly protected from challen

276 the lower respiratory tract of RSV-infected African green monkeys when administered once daily via i

277 y and protective efficacy in cotton rats and African green monkeys, which are among the best availabl

278 virus (HAV) was originally isolated from an African green monkey with hepatitis and appears to repre

279 ers and 4 tissue samples from a NiV-infected African green monkey with viral loads as low as 52 genom

280 elop a more natural NHP model, we challenged African green monkeys with the Bangladesh strain of NiV

281 We infected 35 Asian macaques and African green monkeys with viruses that do or do not exp