1 B. suis primarily infects pigs and is pathogenic to huma
2 avillous trophoblasts (EVTs), B. abortus
and B. suis replicated within single-membrane acidic lysosom
3 ents were shared between only B. abortus
and B. suis, B. abortus shared more fragments and had fewer
4 al isolates (no species name), B. canis,
and B. suis, confirmed that all but the latter two species c
5 ucella abortus, B. melitensis, B. canis,
and B. suis.
6 Brucella abortus, B. melitensis,
and B. suis are pathogenic to humans, whereas B. ovis and B.
7 ersistence of B. abortus, B. melitensis,
and B. suis in mice up to 4 weeks after infection, since del
8 n, and unlike B. abortus, B. melitensis,
and B. suis, B. neotomae has not been observed to infect hum
9 ella species: B. abortus, B. melitensis,
and B. suis.
10 ests of Brucella abortus, B. melitensis,
and B. suis.
11 of infected macrophages and rough
attenuated B. suis strain VTRS1 (a vaccine candidate) induced stron
12 Extensive gene synteny
between B. suis chromosome 1 and the genome of the plant symbion
13 ts previously identified as unique to
either B. suis or B. melitensis were present in the B. abortus
14 sed of Wb and S708 phages that are lytic
for B. suis, B. abortus and B. neotomae.
15 s share a common ancestor that diverged
from B. suis.
16 Furthermore,
B. suis was determined to be paraphyletic in our analyse
17 We have investigated
how B. suis and B. melitensis enter human monocytes and in w
18 B. abortus, B.
melitensis,
B. suis, and B. canis produced identical PCR interspace
19 lla species-Brucella abortus, B.
melitensis,
B. suis, B. canis, and B. ovis-using whole-genome compar
20 ermore, B. melitensis but not B. abortus
nor B. suis interfered with the invasive capacity of EVT-lik
21 ency with cell morphology and attenuation
of B. suis.
22 Comparison
of B. suis with Brucella melitensis has defined a finite se
23 Genome sequencing
of B. suis and B. melitensis revealed that both are complet
24 necessary for the intracellular survival
of B. suis.
25 Only B. suis 1330 appears to have an intact beta-ketoadipate
26 Only B. suis and B. canis isolates clustered together and cou
27 enge with virulent B. abortus strain 2308
or B. suis strain 1330 but no protection against B. meliten
28 field isolates compared to the newly
revised B. suis 1330 reference genome identified on average 13,
29 lassic infectious Brucella reference
strain,
B. suis 1330, was also used.
30 leen and liver, but were less efficient
than B. suis 1330.
31 eotide polymorphisms with B. melitensis
than B. suis.
32 We found
that B. suis is a highly divergent clade with extensive intra
33 The B. suis CtpA protein shared up to 77% homology with CtpA
34 Analysis of
the B. suis genome reveals transport and metabolic capabilit
35 In contrast
to B. suis and B. melitensis, it was found that B. neotomae
36 Our studies showed that smooth
virulent B. suis strain 1330 (S1330) prevented programmed cell de