ライフサイエンスコーパス: BAC

1 BAC biotransformation rates of the enriched microbial co

2 BAC cloning and expression analyses were employed to cha

3 BAC contigs encompass a 1.5-Mb genomic region with 1 Mb

4 BAC in mammography is independently associated with C-IM

5 BAC is defined as two linear calcific deposits forming t

6 BAC recombineering, followed by Tol2 transgenesis, was u

7 BAC transgenic mammalian systems offer an important plat

8 BAC transgenic mice expressing mHTT lacking the N17 doma

9 BAC treatment was ineffective for reducing the pressure

10 BAC Two demonstrated sensitivity and specificity of 93.3

11 rsuit and visual motion processing at 0.015% BAC, reflecting degraded neural processing within extras

12 ements, are significantly impaired at 0.015% BAC, suggesting impaired neural activity within brain re

13 art to become 'sluggish' at as low as 0.035% BAC.

14 In this study, we sequenced 13 BAC clones derived from LCR22A/D and aligned them with 1

15 t of ozone/biological activated carbon (O(3)/BAC) systems.

16 onitromethanes (HNMs), including during O(3)/BAC.

17 bene-Ag(I) complex [Ag(BAC)(2)][CO(2)CF(3)] (BAC = bis(diisopropyl)aminocyclopropenylidene) is report

18 A 3D BAC pool set generated in this study was screened using

19 eatures to classify HCs from SCZs with 89.4% BAC.

20 Using a cocktail of 41 BACs in three colors, all chromosome pairs could be indi

21 sical map, and assembled sequences from 4355 BACs.

22 roups included 50 BAC(+) (case group) and 50 BAC(-) (control group).

23 The groups included 50 BAC(+) (case group) and 50 BAC(-) (control group).

24 solution, we identified and sequenced 15 622 BACs representing the minimal tiling path of 72 052 phys

25 sequencing and with short reads from 31,719 BAC clones, thereby achieving phased blocks with an N50

26 ssembly and paired-end sequences from 62,758 BAC clones provides strong support for the robustness of

27 A Spirodela cytogenetic map containing 96 BAC markers with an average distance of 0.89 Mbp was con

28 A BAC transgenic mouse with functional hCFTR under control

29 Moreover, expression of Pnky from a BAC transgene rescues the differential gene expression a

30 lidate these results in vivo by generating a BAC transgenic mouse, which overexpresses Cyfip1 under t

31 ble to efficiently modify two positions of a BAC simultaneously by co-transformation of a single-stra

32 er group of ten predictors still providing a BAC of 71.7% in 108 patients never used for model discov

33 We now report a BAC mouse model of C9orf72 ALS/FTD that shows decreased

34 lly, we mutated the human mHTT gene within a BAC to express either an aspartic acid or an alanine at

35 ated SCZs from HCs with a balanced accuracy (BAC) of 88.7%, followed by environmental (BAC = 65.1%) a

36 oss-validation (test-fold balanced accuracy [BAC] of 75.0% for 4-week outcomes and 73.8% for and 52-w

37 (BAC) on Au(111) using the molecular adduct BAC-CO(2) as a precursor and determine the structure, ge

38 application of a dicarbene-Ag(I) complex [Ag(BAC)(2)][CO(2)CF(3)] (BAC = bis(diisopropyl)aminocyclopr

39 Altogether, BAC imparts mild and selective reaction conditions that

40 0-1.0 mg O3/mg dissolved organic carbon) and BAC empty bed contact times (EBCT; 15-60 min) on the for

41 ytene chromosomes, clone-based finishing and BAC fingerprint verification, ordering of scaffolds by a

42 age with BAC(+) was 59.18 +/- 8.59 years and BAC(-) was 50.70 +/- 7.93 years.

43 We have generated, sequenced and annotated BAC sequences spanning the S locus, and identified its c

44 ery well described by the band anticrossing (BAC) model in which localized nitrogen states interact w

45 tion, using a whole-genome shotgun assembly, BAC physical mapping, and clone-based finishing.

46 i.e. show lower peak velocities) starting at BAC levels as low as 0.035%.

47 pillary light responses appear unaffected at BAC levels up to 0.065%.

48 nd aligned them with 15 previously available BAC sequences to create a new genetic variation map.

49 the development of a set of universal avian BAC clones that permit rapid anchoring of multiple scaff

50 Experimental results on over 15 000 barley BACs and over 4000 cowpea BACs demonstrate a significant

51 path of 72 052 physical-mapped gene-bearing BACs.

52 One SNP "ARS-BFGL-BAC-27914" reached Bonferroni genome wide significance (

53 recapitulating expression of marker genes by BAC transgenesis or knock-in has generated useful transg

54 This EB phenotype was fully rescued by BAC or cDNA complementation but not by the reduction of

55 ovide an update on phenotypes seen in FVB C9-BAC mice and additional details to successfully use this

56 In C9-BAC mice, alpha-GA(1) reduced GA as well as GP and GR pr

57 ate that RAN proteins drive C9-ALS/FTD in C9-BAC transgenic mice and establish a novel therapeutic ap

58 2020) showed robust ALS/FTD phenotypes in C9-BAC versus non-transgenic (NT) mice and that alpha-GA(1)

59 nd Saxena also show decreased survival of C9-BAC versus NT mice and neuropathological and behavioral

60 the survival or motor phenotypes in C9orf72 BAC transgenic mice originally described by Liu et al.

61 mouse brains, and inhibiting PKR in C9orf72 BAC transgenic mice using AAV-PKR-K296R or the Food and

62 The C9ORF72 BAC transgenic mice will be a valuable tool in the study

63 e to placebo by 1.12 cm, and at a calibrated BAC of 0.05%, SDLP was increased relative to placebo by

64 neration method for beaded activated carbon (BAC) loaded with n-dodecane, a high molecular weight vol

65 nes, ozone, and biological activated carbon (BAC), applied as pretreatments to mitigate organic chemi

66 Beaded activated carbon (BAC, microwave-absorbing) and a polymeric adsorbent (V50

67 Using the concept of boronic acid catalysis (BAC), electrophilic activation of carboxylic acids leads

68 ncapsulation of bovine adrenocortical cells (BACs) in alginate (enBACs).

69 s limitation, we generated and characterized BAC transgenic P2rx4 tdTomato reporter mice.

70 In chimeric BACs, the mTert promoter became strongly repressed in th

71 ESC lines with chimeric BACs, in which two TERT promoters were swapped, were als

72 that they were found in human and chimpanzee BAC and FOSMID clones sequenced as part of the original

73 Benzalkonium chlorides (BACs) are emerging pollutants.

74 biotransformation of benzalkonium chlorides (BACs)-an active ingredient of many disinfectants-to benz

75 tured primary bovine articular chondrocytes (BACs) were subjected to cyclic tensile strain (CTS) load

76 Using these chromatinized BACs, we showed that hTERT silencing during differentiat

77 and Sanger sequences of over 90 Y chromosome BAC clones.

78 in receptor bacterial artificial chromosome (BAC) and enhanced green fluorescent protein (eGFP) repor

79 A bacterial artificial chromosome (BAC) carrying the complete hCFTR gene including regulato

80 The bacterial artificial chromosome (BAC) clone Merlin (ME) expresses abundant UL128-131, is

81 ng reads to bacterial artificial chromosome (BAC) clones (in the context of the combinatorial pooling

82 uence eight Bacterial Artificial Chromosome (BAC) clones spanning the horse MHC class II region.

83 , we used a bacterial artificial chromosome (BAC) construct that expresses luciferase under the contr

84 carrying a bacterial artificial chromosome (BAC) containing the full human C9orf72 gene with either

85 nstructed a bacterial artificial chromosome (BAC) contig, and obtained a continuous genomic sequence

86 assembly, a bacterial artificial chromosome (BAC) physical map, and assembled sequences from 4355 BAC

87 Using Bacteria Artificial Chromosome (BAC) recombineering and a transgenic knock-in, we have g

88 trategy for Bacterial Artificial Chromosome (BAC) recombineering based on co-selection is described.

89 romatinized bacterial artificial chromosome (BAC) reporters in human fibroblasts, we found that ETV5

90 constructed bacterial artificial chromosome (BAC) reporters using human and mouse genomic DNAs encomp

91 single-copy bacterial artificial chromosome (BAC) reporters, covering hTERT and mTERT genes and their

92 reads, and bacterial artificial chromosome (BAC) sequencing approaches.

93 pathogenic bacterial artificial chromosome (BAC) that is used to study MCF.

94 ws a single Bacterial Artificial Chromosome (BAC) transgene to direct sparse labeling of genetically-

95 ing a human bacterial artificial chromosome (BAC) transgene were generated, resulting in plasma level

96 Using bacterial artificial chromosome (BAC) transgenic HeLa and mouse embryonic stem cells stab

97 studies of bacterial artificial chromosome (BAC) transgenic mice harboring this expansion described

98 ng HDC-EGFP bacterial artificial chromosome (BAC) transgenic mice in which EGFP expression is control

99 ional VIPR2 bacterial artificial chromosome (BAC) transgenic mouse models of VIPR2 CNV.

100 igh-quality bacterial artificial chromosome (BAC)-based assemblies to evaluate base-level accuracy.

101 reported a bacterial artificial chromosome (BAC)-based lymphatic reporter mouse, where EGFP is expre

102 y developed bacterial artificial chromosome (BAC)-based MHV reverse genetics system.

103 uses in the bacterial artificial chromosome (BAC)-derived clinical HCMV strain TB40/E-mCherry.

104 n by either bacterial artificial chromosome (BAC)-derived virus in Jjhan cells or wild-type HHV-6A st

105 tgun reads, bacterial artificial chromosome (BAC)-end sequences and genotype-by-sequencing genetic ma

106 e establish bacterial artificial chromosome (BAC)-transgenic mouse lines with biased mTEC(lo) or mTEC

107 y developed bacterial artificial chromosome (BAC)-transgenic mouse model, we demonstrate that Lgr5 ex

108 y the B95-8 bacterial artificial chromosome (BAC).IMPORTANCE Epstein-Barr virus (EBV) infects the maj

109 e only 6278 bacterial artificial chromosome (BACs) in the physical map were sequenced, fine structure

110 cloned as a bacterial artificial chromosome [BAC]) has a 4-bp deletion that disrupts GP129, which enc

111 quences in bacterial artificial chromosomes (BAC) to analyze the genomic region surrounding the Eya1

112 lly mapped bacterial artificial chromosomes (BACs) containing Spirodela DNA inserts with little or no

113 to deliver bacterial artificial chromosomes (BACs) into cells by viral transduction.

114 Bacterial artificial chromosomes (BACs) provide a stable, genetically defined source of vi

115 study, VZV bacterial artificial chromosomes (BACs) were generated with small (Delta30S), medium (Delt

116 oning into bacterial artificial chromosomes (BACs), and then virus is regenerated by DNA transfection

117 mids up to bacterial artificial chromosomes (BACs; 144 kb deletion) have been achieved by this method

118 a more efficient approach than the classical BAC transgenesis, resulting in complete BAC integration

119 d SeqCNV to both bacterial artificial clone (BAC) and human patient NGS data to identify CNVs.

120 ical BAC transgenesis, resulting in complete BAC integration with predictable end sequences, thereby

121 bind catechol to form boron "ate" complexes (BACs) that alter the electron density on the oxygen atom

122 pruritus and serum bile acid concentration (BAC) as well as an improvement of serum liver tests.

123 g the permitted blood alcohol concentration (BAC) for drivers is a common public health intervention

124 Blood alcohol concentration (BAC) is unable to be determined on-site, as it typically

125 At a calibrated blood alcohol concentration (BAC) of 0.02%, SDLP was increased relative to placebo by

126 on deficits at blood-alcohol concentrations (BACs) above about 0.04%.

127 The conditional BAC transgenesis offers a novel strategy to model CNVs w

128 reathalyzers estimate Blood Alcohol Content (BAC) from the concentration of ethanol in the breath.

129 over 15 000 barley BACs and over 4000 cowpea BACs demonstrate a significant improvement in the qualit

130 sgene expression via crossing with Drd1a-Cre BAC transgenic mice rescued the dopamine D2 receptor abn

131 upling parameters in the band anti-crossing (BAC) k . p model for N-rich alloys.

132 d rapid capture strategies using the current BAC set provide the basis for assembling numerous avian

133 C, bis(diisopropylamino) cyclopropenylidene (BAC), elemental Se, Ph(2)CO, PhCH=CHCOPh, and PhCN at ro

134 sit bis(diisopropylamino)cyclopropenylidene (BAC) on Au(111) using the molecular adduct BAC-CO(2) as

135 of bis(diisopropylamino)cyclopropenylidene (BAC) to provide PhB((i)Pr2Im)3Fe(CN)(N2)(BAC).

136 crosslinker N, N'-bis (acryloyl) cystamine (BAC), sulfated 2-acrylamido-2-methyl-1-propanesulfonic a

137 egradation of a N,N'-bis(acryloyl)cystamine (BAC) cross-linked core out of a non-degradable pNIPAM sh

138 cept, we generated D1-dopamine receptor (D1) BAC MORF mice that label about 1% striatal D1-expressing

139 Four microbial communities degrading BACs were developed from sewage (SEW), activated sludge

140 Lowering the driving BAC limit to 0.05 g/dL from 0.08 g/dL in Scotland was no

141 rize a UL93 stop mutant virus (UL93st-TB40/E-BAC) to demonstrate that the absence of this protein doe

142 ated cells from DeltaSox2-eGFP, Neurog1-eGFP BAC and DeltaOMP-eGFP strains of uninjured and olfactory

143 e the species mismatch, the mouse Prox1-EGFP BAC enabled a reliable expression of EGFP in Prox1-expre

144 atic reporter rat using the mouse Prox1-EGFP BAC.

145 Finally, we show that Sox8-EGFP BAC mice can be used to interrogate the altered dSPN dev

146 ive expression of EGFP in dSPNs of Sox8-EGFP BAC mice is maintained at postnatal timepoints.

147 marker of embryonic dSPNs and the Sox8-EGFP BAC transgenic mice are an excellent tool to study the d

148 Sox8 in the embryonic striatum and Sox8-EGFP BAC transgenic mice specifically reveal the direct pathw

149 (+) cells in the amygdala of the AT(2)R-eGFP-BAC reporter mouse.

150 hromosomes contain most of the gene-enriched BACs and are characterized by high recombination rates,

151 y (BAC) of 88.7%, followed by environmental (BAC = 65.1%) and genetic (BAC = 55.5%) classifiers.

152 vitroby deriving virus from a self-excising BAC in fibroblasts and repressing RL13 and UL128L.

153 In overexpression experiments, BACs were electroporated with a plasmid encoding CD44-IC

154 ld paired-end sequences assisted by fivefold BAC-to-BAC sequences and a high-resolution genetic map.

155 uses derived from TR-BAC, TB40-BAC4, and FIX-BAC in either fibroblast or epithelial cells was associa

156 ing UL128L nucleotides from TB40-BAC4 or FIX-BAC.

157 nucleotides in UL128L from TB40-BAC4 or FIX-BAC.

158 Thus, an efficient method for BAC transgenesis in rats would be valuable.

159 a full copy of the gene, generating the {for(BAC)} rescue allele.

160 Genomes of four BAC degrading and nondegrading BIOMIG1 phenotypes were s

161 sed c-Rel specifically in mouse B cells from BAC-transgenic gene loci and demonstrate that c-Rel prot

162 neurite shortening in neuronal cultures from BAC transgenic R1441G-LRRK2 mice.

163 sion, neurite length of primary neurons from BAC transgenic G2019S-LRRK2 mice returned back to wild-t

164 reaction involves carbon atom transfer from BAC to create a cyanide ligand along with the alkyne (i)

165 n E. coli resulted in formation of BDMA from BACs at a rate of 14 muM h(-1).

166 Viruses were generated from BACs containing the genomes of strains TR, TB40, FIX, an

167 h intracellular RAN aggregates in C9-ALS/FTD BAC mice.

168 loskeletal phenotype of the homozygous G608G BAC-transgenic progeria mouse model, and to determine th

169 P2X4 receptor-expressing cells, we generated BAC transgenic mice expressing tdTomato under the contro

170 eutic strategies, difficulties of generating BAC transgenic rats have hindered progress.

171 by environmental (BAC = 65.1%) and genetic (BAC = 55.5%) classifiers.

172 ell type labeled in adult pigmented Cdh3-GFP BAC transgenic mice.

173 ostnatal day 0 (PD0) Drd1a-tdTomato/Drd2-GFP BAC transgenic mice, and at the receptor level by costai

174 Here we show that HSPA1B BAC transgenes and endogenous Hsp70 genes turn on 2-4 mi

175 In BAC transgenic zebrafish, cav1 regulatory sequences drov

176 on of a narrow intermediate band (E- band in BAC model) with the minimum at the Gamma point of the Br

177 Bile analyses showed an increase in BAC with 4-PB.

178 than those reported to date, are involved in BAC biotransformation in various habitats.

179 integrase and a dioxygenase were involved in BAC biotransformation.

180 ntrast, about 90% Treg depletion obtained in BAC transgenic Foxp3.LuciDTR4 mice failed to induce comp

181 ks after the onset of the motor phenotype in BAC-Q72 mice.

182 TA rates in Scotland after this reduction in BAC limit for drivers (1.07, 1.02-1.13; p=0.007 in the f

183 in England and Wales, where the reduction in BAC limit for drivers did not occur, we found a 7% incre

184 After the reduction in BAC limits for drivers in Scotland, we found no signific

185 is potential linkage, the STN was studied in BAC transgenic and Q175 knock-in mouse models of HD.

186 Here, using AXIN2 lineage tracing in BAC-transgenic mice, we confirm the regenerative potenti

187 Neither CRISPR/Cas9 nor TALEN increased BAC transgenesis.

188 nerated tissue-specific cell cycle indicator BAC transgenic mouse lines.

189 The infectious BAC (iBAC) library contains 184,320 clones with an avera

190 Previously, expensive and labor-intensive BAC-based techniques were used to sequence the Y for a h

191 Our findings suggest that changing the legal BAC limit for drivers in isolation does not improve RTA

192 cular behaviours across a range of ultra-low BACs (<0.035%).

193 H administration across a range of ultra-low BACs (<=0.035%).

194 ncorporate FISH utilizing A. thaliana mapped BAC clones to allow the chromosomes of field cress to be

195 r neighboring loci, via recombinase-mediated BAC targeting.

196 Viruses derived from a Merlin-BAC derivative in which RL13 and UL128L were either muta

197 This was not observed for Merlin-BAC, from which the vector is excised in derived viruses

198 Viruses derived from Merlin-BAC in fibroblasts had mutations in UL128L, but mutation

199 B40, FIX, and Merlin, as well as from Merlin-BAC recombinants containing variant nucleotides in UL128

200 sent in various environments and mineralizes BACs.

201 The strain BIOMIG1 mineralizes BACs at a rate up to 2.40 mumol hr(-1) 10(-11) cells.

202 regulatory elements in chimeric human/mouse BAC reporters.

203 his end, we generated a novel multicistronic BAC (bacterial artificial chromosome) transgenic mouse l

204 ne (BAC) to provide PhB((i)Pr2Im)3Fe(CN)(N2)(BAC).

205 ne (BAC One) or gram-negative bacteria/none (BAC Two) and compared to Gram stain results.

206 samples were scored as bacteria/fungi/none (BAC One) or gram-negative bacteria/none (BAC Two) and co

207 A novel BAC transgenic Neurog3 reporter detected two types of mi

208 imilar between the two wastewaters across O3/BAC conditions.

209 followed by biological activated carbon (O3/BAC) is being considered as a key component of reverse o

210 Using a laboratory-scale O3/BAC system treating two nitrified wastewater effluents,

211 calculated DBP-associated toxicity of the O3/BAC-treated chloraminated effluents were comparable or s

212 The O3/BAC-treated wastewaters met regulatory levels for trihal

213 and (ii) the problem of de novo assembly of BAC clones.

214 The generation and characterization of BAC-transgenic eGFP reporter mouse lines has revealed th

215 Using a combination of BAC sequencing and genome analysis, we discovered three

216 Here we report the development of BAC libraries, sub genome specific physical maps, and a

217 , two laboratories report the development of BAC transgenic mice that recapitulate features of the hu

218 culations of the molecular binding energy of BAC on Au(111) and its electronic structure.

219 us accumbens, thalamus, and hypothalamus) of BAC aldh1l1-translational ribosome affinity purification

220 the anchoring of 100 Mb of WGS and 420 Mb of BAC sequences, an exploration of genetic diversity along

221 ted genome assembly; ii) demonstrated NGS of BAC pools as a potential approach for mining candidates

222 ith age, diabetes, hypertension, presence of BAC and history of surgery and drug intake.

223 divided into two groups based on presence of BAC on mammography using the WIPRO GE - DMR PLUS mammogr

224 vector to only two steps: a single round of BAC modification followed by a retrieval step.

225 We then used a second round of BAC recombineering to create deletion constructs of thes

226 ft of the unstable repeat DNA in a subset of BAC-expressing neurons results in the in-frame translati

227 the genes involved in the biodegradation of BACs is crucial for better understanding the fate of BAC

228 s loading promoted the de-differentiation of BACs by enhancing CD44 cleavage and CD44-ICD production.

229 crucial for better understanding the fate of BACs in the environment and developing treatment strateg

230 that BIOMIG1 plays a key role on the fate of BACs in the environment and genes, other than those repo

231 ave applications for controlling the fate of BACs in the environment.

232 ate significantly increased the life span of BACs.

233 u hybridization (mcFISH), using an optimized BAC pooling strategy, to validate its physical map and c

234 es were flooded with SmartProbes (BAC One or BAC Two) and evaluated by fluorescence microscopy (witho

235 to LCR22A, using the variation map from our BAC analysis to help resolve allele ambiguity, and by pe

236 regions were possible because of overlapping BAC clones, generated by an expensive and labor-intensiv

237 ng 82 S-linked genes anchored to overlapping BACs.

238 ses, displaying good correlation to parallel BAC measurements.

239 cytes during angiogenesis, we crossed Pdgfrb(BAC)-CreER(T2) mice into RiboTag(flox/flox) mice.

240 tween LRRK2 and tau, we crossed LRRK2 R1441G BAC transgenic mice (Mus musculus) with tau P301S mutant

241 f ZsG by mice transgenic for the recombinant BAC appears to be a faithful surrogate for TSLP expressi

242 Two groups recently reported BAC mouse models that produce RNA foci and RAN proteins

243 lly isolated syndrome for multiple sclerosis BAC = 56.7%).

244 In this study, through screening BAC libraries and sequencing and annotating the targeted

245 e within-diagnosis validation sample (HC-SCZ BACs, cognition = 70.5%; environment = 65.8%; genetics =

246 The use of co-selection BAC recombineering reduces the DNA manipulation needed t

247 tion mapping to identify, and then sequence, BAC clones and genome scaffolds to construct S/s haploty

248 esource for anchoring and ordering sequenced BAC and next generation sequencing (NGS) contigs.

249 useful for anchoring and ordering sequenced BAC and NGS based contigs for assembling a high-quality,

250 Exploration of these sequenced BACs revealed that although distal ends of chromosomes c

251 embly of the pig Y Chromosome, by sequencing BAC and fosmid clones from Duroc animals and incorporati

252 ve generated for the first time, human SIRPA BAC transgenic rats, for which the gene is faithfully ex

253 To do this, human SIRPA BAC was modified with elements to work in coordination w

254 ite-out validation across 44 European sites (BAC of 72.1% for 4-week outcomes and 71.1% for 52-week o

255 rneal scrapes were flooded with SmartProbes (BAC One or BAC Two) and evaluated by fluorescence micros

256 ns of the more toxic brominated DBP species, BAC and GAC treatment favored brominated DBP species by

257 Compared to Gram stain, BAC One demonstrated sensitivity and specificity of 80.0

258 s and sequencing and annotating the targeted BAC clones, we generated orthologous genomic sequences s

259 Here we analyzed Drd1a-tdTomato BAC transgenic mice and found that the dopamine D1 recep

260 The BAC interaction results in the formation of a narrow int

261 The BAC map was partitioned by sub genomes through alignment

262 The BAC transgene drives cell-type-specific transcription of

263 In Scotland, on Dec 5, 2014, the BAC limit for drivers was reduced from 0.08 g/dL to 0.05

264 2013, and Dec 31, 2016, before and after the BAC limit came into effect on Dec 5, 2014.

265 The splitting of the conduction band by the BAC interaction is further confirmed by a direct observa

266 dictions consider a similar reduction in the BAC limit for drivers.

267 Mean C-IMT in the BAC(+) group was 0.86 +/- 0.21 mm vs. 0.71 +/- 0.12 mm i

268 0.86 +/- 0.21 mm vs. 0.71 +/- 0.12 mm in the BAC(-) group.

269 ASO7 had a similar effect in the BAC-Q72 SCA2 mouse model, and in both mouse models it no

270 Here, sequencing of the BAC clone showed that the long unique region (LUR) of th

271 ered the physical/chemical properties of the BAC.

272 Overall, these results indicate that the BAC-based MHV reverse genetics system will be useful for

273 e previously sequenced strain from which the BAC was derived, and identified the duplication and tran

274 cy in tuning the electron density within the BAC and the resulting oxidation potential.

275 Sec23b pancreatic function reside within the BAC transgenes.

276 These BAC sequences constitute a resource to improve the effic

277 ering to create deletion constructs of these BAC reporters to localize enhancer activity more precise

278 Three BAC libraries were constructed, fingerprinted, and integ

279 tegrated with wearable devices for real-time BAC monitoring.

280 are HarvEST:Barley provides facile access to BAC sequences and their annotations, along with the barl

281 ting breath alcohol concentrations (BrAC) to BAC estimations, as they involve portable equipment with

282 detects ethanol in the breath equivalent to BAC from 0.01% to 0.2%.

283 can occur not only during isolation prior to BAC cloning but also when virus is regenerated.

284 ed-end sequences assisted by fivefold BAC-to-BAC sequences and a high-resolution genetic map.

285 Propagation of viruses derived from TR-BAC, TB40-BAC4, and FIX-BAC in either fibroblast or epit

286 We also demonstrate that two BAC transgenes spanning Sec23b rescue the lethality of m

287 We used BAC recombineering to first create GFP reporter construc

288 Using BAC transgenesis, we created a mouse model with a humani

289 Using BAC-Cre transgenic mice with viral tracing techniques, w

290 mouse models expressing these mutants using BAC recombineering technology and investigated their abi

291 bsequent restoration of pathogenicity, using BAC-based mutagenesis.

292 Utilizing BAC transgenesis, we generated transgenic zebrafish in w

293 correctly resolves 337 out of 341 validation BACs sampled from known segmental duplications and provi

294 aa 1100 to 1150 (BAC16Delta1100-1150, where BAC is bacmid) showed reduced replication and persistenc

295 We have identified conditions under which BAC-derived viruses containing an intact, wild-type geno

296 Mean age with BAC(+) was 59.18 +/- 8.59 years and BAC(-) was 50.70 +/-

297 epresents a new member of RO associated with BAC degradation, and have applications for controlling t

298 structed, fingerprinted, and integrated with BAC-end sequences (BES) to produce a de novo whole-genom

299 ation generally decreased significantly with BAC treatment at 15 min EBCT, but little further reducti

300 We found that, compared with BACs in monolayer culture, encapsulation in alginate sig