ライフサイエンスコーパス: BALF

1 BALF exosomes from asthmatics might contribute to subcli

2 BALF ferritin and iron were elevated in participants who

3 BALF from an IPF patient contained ADP-ribosyl-HNP-ornit

4 BALF iron and ferritin were higher in participants with

5 BALF Iron parameters were compared to systemic markers o

6 BALF supernatant was analyzed using an aptamer assay to

7 BALF was also collected and tested from negative control

8 BALF was assessed for pepsin, bile salts, interleukin-8

9 BALF was collected from ALI/ARDS patients within 48 hrs

10 BALF was tested for chitinase activity and YKL-40 (an en

11 BALFs were standardized in protein concentration.

12 Pepsin was detected in 11 of 15 BALF samples signifying aspiration (median: 18 ng/mL; ra

13 Upon testing 175 BALF, we were able to analyze positive agreement of 181

14 ptomatic HCMV disease, proposing that CCL-18 BALF levels could serve as a marker.

15 Furthermore, CCL-18 BALF levels were significantly higher in 8 LTRs who addi

16 a significant increase of CCL-18 and CCL-20 BALF levels (P < 0.001, Wilcoxon signed-rank test) and a

17 For comparison, we included 34 BALF specimens (2 for each CARV case) that were negative

18 approximately 1 log(10) lower median HHV-6B BALF viral load, as well as a lower risk of overall mort

19 in all three tested subjects with HHV-6B(+) BALF and sufficient tissue RNA preservation.

20 We detected HHV-6B(+) BALF from 147 of 553 (27%) individuals.

21 1.10), compared with subjects with HHV-6B(+) BALF not receiving antivirals.

22 Subjects with HHV-6B(+) BALF who received antivirals within 3 days pre-BAL had a

23 els to evaluate the association of HHV-6B(+) BALF with overall mortality, death from respiratory fail

24 Subjects with HHV-6B(+) BALF, with or without copathogens, had significantly inc

25 -4.01) compared with subjects with HHV-6B(-) BALF.

26 If SP-A-/- BALF was mixed in equal amounts with SP-D-/- BALF, TNF-a

27 samples (retrospective part), as well as all BALF samples received for P. jirovecii analysis over a p

28 results suggest that children MPP can alter BALF cytokines signatures which associate with disease s

29 By mRNA analysis, BALF cells demonstrated a time-dependent phenotypic shif

30 ized, there was little effect on the AHR and BALF cellular differential.

31 o AHR, and a selective decrease in blood and BALF eosinophils, lung Il13 levels, collagen, and smooth

32 RNA was examined for transcript levels, and BALF was examined for cytokine protein profiles.

33 We report increased MIF in the lung and BALF of sensitized wild-type mice.

34 al colony counts, BALF total cell number and BALF protein concentration significantly decreased at da

35 n St3gal3 mutants, whereas peribronchial and BALF eosinophil numbers were greater in the mutants, wit

36 CS-exposed mice showed increased plasma and BALF glycerolipids and glycerophospholipids.

37 uced IL-6 and TNF-alpha levels in plasma and BALF.

38 , GT is detectable in mouse lungs, serum and BALF during neutropenic IA, suggesting that GT may be us

39 were captured in mice sera, lung tissues and BALF, including purines, pyrimidines, acylcarnitines, fa

40 were observed in mice sera, lung tissues and BALF, indicating the molecular differences between syste

41 stology, AHR, T regulatory cells (Tregs) and BALF cytokines was examined.

42 ALI/ ARDS BALF demonstrated potent alphaSMA induction with a mean

43 There was no correlation between ALI/ARDS BALF-induced alphaSMA and procollagen 3 induction (r = -

44 ALI/ARDS BALF-induced myofibroblast differentiation is partially

45 receptor inhibitor SB431542 reduced ALI/ARDS BALF-stimulated alphaSMA induction by 52% (p < .005).

46 ty of human MDMs stimulated with LPS or ARDS BALF.

47 Macrophages were isolated from asthmatic BALF and derived from THP-1 cells and human monocytes.

48 observational trial the association between BALF cytokine/chemokine profiles and subsequent infectio

49 No major differences were observed between BALF exosomes from before and after allergen provocation

50 Blood, BALF, lungs and spleen were collected after 5 weeks of e

51 ls and cytokines were assessed in the blood, BALF, lungs and spleen.

52 significantly lower bacterial burden in both BALF and lung tissue than did Spp1(-/-) mice.

53 esulted in WT-like lung injury severity, but BALF leukocyte levels increased only in WT and A1-KO mic

54 tein (NLRP) 3 and pro-IL-1beta expression by BALF macrophages, as well as the caspase-1-mediated gene

55 Concurrent BALF lymphocyte subsets were examined by flow cytometry,

56 In contrast, BALF neutrophils and AHR increased, but eosinophils decr

57 y 1 post infection, bacterial colony counts, BALF total cell number and BALF protein concentration si

58 Finally, pure SP-D added to SP-D-/- BALF inhibited TNF-alpha production by BAM-B. dermatitid

59 BALF was mixed in equal amounts with SP-D-/- BALF, TNF-alpha production by BAM-B. dermatitidis was in

60 DD therapy also further downregulated BALF ILs and cytokines including Jak-STAT (Janus kinases

61 The differentially expressed BALF proteins also map to aryl hydrocarbon signaling, co

62 ronchoalveolar lavage (BAL) cells and fluid (BALF) proteins in recently diagnosed sarcoidosis cases.

63 At the end of each phase, BAL fluid (BALF) and plasma samples were obtained.Measurements and

64 proteins and protein pathways in BAL fluid (BALF) would distinguish children with neuroendocrine cel

65 beta1 in bronchoalveolar lavage (BAL) fluid (BALF).

66 responsiveness (AHR), bronchoalveolar fluid (BALF) cellular and cytokine profile, antigen-specific Ig

67 ines IL-4 and TSG6 in bronchoalveolar fluid (BALF).

68 uated by using bronchoalveolar lavage fluid (BALF) analysis and pathology.

69 Bronchoalveolar lavage fluid (BALF) analysis demonstrated an approximate 18-fold incre

70 ation in both bronchioalveolar lavage fluid (BALF) and blood of doxycycline-treated CCSP-rtTA/(tetO)7

71 detectable in bronchoalveolar lavage fluid (BALF) and culture medium of lung epithelial cells.

72 Lung tissue, bronchoalveolar lavage fluid (BALF) and draining lymph node cells were analysed for in

73 e cytokines in bronchoalveolar lavage fluid (BALF) and explore predicting factors of severe MPP in ch

74 We examined bronchoalveolar lavage fluid (BALF) and histological lung sections after 1 week, 1 mon

75 atant of mouse bronchoalveolar lavage fluid (BALF) and in nonciliated bronchiolar cells, alveolar typ

76 neumoniae, and bronchoalveolar lavage fluid (BALF) and lung CFU values were determined.

77 to 12 wk, and bronchoalveolar lavage fluid (BALF) and lung tissue collected after the last challenge

78 e (CARDS) toxin in bronchiolar lavage fluid (BALF) and lung.

79 bmGT in serum, bronchoalveolar lavage fluid (BALF) and lungs of A. fumigatus-infected chronic granulo

80 etween matched bronchoalveolar lavage fluid (BALF) and plasma, identifies the degree of congruence be

81 ar profiles in bronchoalveolar lavage fluid (BALF) and serum IgG and IgE antibody levels to whole bac

82 nflammation in bronchoalveolar lavage fluid (BALF) and Th2 responses in lung explants and draining LN

83 BORT reduced bronchoalveolar lavage fluid (BALF) and tissue eosinophils and inflammation, IL-5, IL-

84 infection had bronchoalveolar lavage fluid (BALF) available for analysis.

85 d in lungs and bronchoalveolar lavage fluid (BALF) by multiparametric flow cytometry.

86 erial burdens, bronchoalveolar lavage fluid (BALF) cell counts, cell types, and cytokine levels were

87 by increased broncho-alveolar lavage fluid (BALF) cells and cytokines (IL-6 and TNF-alpha), increase

88 ial clearance, bronchoalveolar lavage fluid (BALF) characterization, lung histology, lung cell prolif

89 by 80% in COPD bronchoalveolar lavage fluid (BALF) due to serine protease cleavage, primarily by cath

90 matory role of bronchoalveolar lavage fluid (BALF) exosomes in patients with sarcoidosis and to find

91 We studied bronchoalveolar lavage fluid (BALF) from 36 patients with ARDS (20 survivors, 16 non-s

92 ung tissue and bronchoalveolar lavage fluid (BALF) from a non-lethal mouse model with influenza A vir

93 ermine whether bronchoalveolar lavage fluid (BALF) from ALI/ARDS patients can induce myofibroblast di

94 or = 0.05) in bronchoalveolar lavage fluid (BALF) from asbestos-exposed mice, but to a lesser extent

95 re measured in bronchoalveolar lavage fluid (BALF) from children with CF (n = 57; 6.1 +/- 5.9 yr) and

96 ers present in bronchoalveolar lavage fluid (BALF) from chlorine gas exposed mice.

97 from cells in bronchoalveolar lavage fluid (BALF) from COVID-19 patients that were used to sequence

98 ly detected in bronchoalveolar lavage fluid (BALF) from immunocompromised subjects with lower respira

99 Bronchoalveolar lavage fluid (BALF) from LPS-treated MMP-8(-/-) mice had more MIP-1alp

100 s in blood and bronchoalveolar lavage fluid (BALF) from mechanically ventilated patients with acute r

101 ed with LPS or bronchoalveolar lavage fluid (BALF) from patients with ARDS.

102 re measured in bronchoalveolar lavage fluid (BALF) from patients with N-ERD (n = 22), patients with N

103 In bronchoalveolar lavage fluid (BALF) from subjects with IPF, we found short-fragment hy

104 (MLE-15) with bronchoalveolar lavage fluid (BALF) harvested from mice infected with S. pneumoniae.

105 tokines in the bronchoalveolar lavage fluid (BALF) in a murine model of allergic asthma.

106 tionation from bronchoalveolar lavage fluid (BALF) in vivo.

107 tection in the bronchoalveolar lavage fluid (BALF) indicates HCMV replication in the pulmonary compar

108 Culture of bronchoalveolar lavage fluid (BALF) is the gold standard for detection of pathogens in

109 Bronchoalveolar lavage fluid (BALF) levels of SOCS3 were reduced in asthmatics and in

110 ion that local bronchoalveolar lavage fluid (BALF) levels of vitamin D are severely deficient in HIV(

111 nt increase in bronchoalveolar lavage fluid (BALF) macrophages and neutrophils and whole lung tissue

112 expression by bronchoalveolar lavage fluid (BALF) macrophages from asthmatic subjects and identify h

113 3 cytokines in bronchoalveolar lavage fluid (BALF) of 88 children with MPP and 26 children with forei

114 T cells in the bronchoalveolar lavage fluid (BALF) of Af5517-aspirated mice displayed decreased gamma

115 lated from the bronchoalveolar lavage fluid (BALF) of M bovis BCG-infected mice contain the mycobacte

116 levels in the bronchoalveolar lavage fluid (BALF) of participants enrolled in the SubPopulations and

117 ntified in the bronchoalveolar lavage fluid (BALF) of patients with acute lung injury.

118 isolated from bronchoalveolar lavage fluid (BALF) of patients with asthma and idiopathic pulmonary f

119 ome profile in bronchoalveolar lavage fluid (BALF) of patients with sarcoidosis, but their role in as

120 Bronchoalveolar lavage fluid (BALF) offers a potential means to diagnose acute rejecti

121 ed proteins in bronchoalveolar lavage fluid (BALF) on the interaction of BAM and Blastomyces dermatit

122 y increases in bronchoalveolar lavage fluid (BALF) protein and histochemical evidence of CD45(+) and

123 zone increased bronchoalveolar lavage fluid (BALF) protein, a marker of lung permeability, in all gen

124 enter study on bronchoalveolar lavage fluid (BALF) samples obtained from 296 patients with various un

125 All archived bronchoalveolar lavage fluid (BALF) samples that had previously tested positive for P.

126 Neutrophils in bronchoalveolar lavage fluid (BALF) served as markers of inflammation.

127 Bronchoalveolar lavage fluid (BALF) was analysed for total protein, lactate dehydrogen

128 Bronchoalveolar lavage fluid (BALF) was collected from children undergoing clinically

129 Rhinoceros bronchial alveolar lavage fluid (BALF) was found to have an inhibitory effect on the Ultr

130 ng activity of bronchoalveolar lavage fluid (BALF) was observed following secondary CA04 challenge of

131 Broncho alveolar lavage fluid (BALF) was sampled from donors prior to procurement and i

132 ung tissue and bronchoalveolar lavage fluid (BALF) were analyzed for inflammation, as well as various

133 sine levels in bronchoalveolar lavage fluid (BALF) were increased by approximately 3-fold.

134 7 cytokines in bronchoalveolar lavage fluid (BALF), accompanied by an increment in transcription fact

135 Bronchoalveolar lavage fluid (BALF), airway inflammation and hyperresponsiveness (AHR)

136 leen cells and bronchoalveolar lavage fluid (BALF), and cellular distribution in BALF were then exami

137 nalysis of the bronchoalveolar lavage fluid (BALF), and characterization of ex vivo cytokine response

138 xposure, SpO2, bronchoalveolar lavage fluid (BALF), and histologic analyses were performed.

139 and macrophages in bronchiolar lavage fluid (BALF), as well infiltrating inflammatory cells, and decr

140 r cells in Wsh bronchoalveolar lavage fluid (BALF), despite similar levels of cytokines and chemokine

141 plasma to the bronchoalveolar lavage fluid (BALF), protein and CINC-1 concentrations in the BALF, an

142 surements, and bronchoalveolar lavage fluid (BALF), serum, and lungs were collected on day 28 for fur

143 heir serum and bronchoalveolar lavage fluid (BALF), significantly reduced inflammatory cytokine level

144 bile salts) in bronchoalveolar lavage fluid (BALF).

145 d cytokines in bronchoalveolar lavage fluid (BALF).

146 biomarkers in bronchoalveolar lavage fluid (BALF).

147 4/CD8 ratio in bronchoalveolar lavage fluid (BALF).

148 OPN levels in bronchoalveolar lavage fluid (BALF).

149 tion increased bronchoalveolar lining fluid (BALF) adenosine comparably in WT and A1-KO mice.

150 ound in bronchoalveolar lavage (BAL) fluids (BALF) of LTR at CLAD diagnosis, are elevated and potenti

151 al protein in bronchoalveolar lavage fluids (BALF) from patients with sepsis-related acute respirator

152 s detected in bronchoalveolar lavage fluids (BALF) in a macrophage- and neutrophil-dependent manner.

153 al culture of bronchoalveolar lavage fluids (BALF) is labor-intensive, and the delay involved in perf

154 e assessed in bronchoalveolar lavage fluids (BALFs) after allergen challenge.

155 nificant interstrain variation was found for BALF inflammatory cells and protein (heritability estima

156 In this multicenter study the LFA assay from BALF demonstrated good diagnostic performance for IA tha

157 and protein pathways can be determined from BALF of children with chILD, and these hold promise to f

158 ms were to investigate whether exosomes from BALF have LT biosynthetic capacity and to explore phenot

159 nce of miRNAs was confirmed in exosomes from BALF of both asthmatic patients and healthy control subj

160 isolated alveolar macrophages harvested from BALF from HA-treated mice.

161 Native SP-BN isolated from BALF also killed bacteria but only at acidic pH; the bac

162 Exosomes were isolated from BALF from healthy control subjects (n = 10) and patients

163 n of CXCR1 was decreased on neutrophils from BALF compared with blood (median difference in MFI 1337,

164 adults, did not induce IL-1beta release from BALF macrophages.

165 serine proteases induced APOE secretion from BALF macrophages through protease-activated receptor 2.

166 underlying hematological malignancy) who had BALF galactomannan (GM) ordered between 2013 and 2019 at

167 Among CARV infected patients, a high BALF concentration of either CXCL10 or CXCL11 was predic

168 ith marked signs of airway remodelling, high BALF eosinophilia, increased BALF pro-inflammatory cytok

169 Mouse BALF and human BALF had a strong positive correlation with 2040 metabol

170 their presence in in vitro chlorinated human BALF.

171 metabolites present across mouse and human, BALF and plasma.

172 Furthermore, transfer of immune BALF obtained from nonasthmatic, but not asthmatic, dono

173 In BALF, the levels of IL-5, IL-13, eotaxin-1 and eotaxin-2

174 rd elevated neutrophil counts (P = 0.002) in BALF and increased mortality (P = 0.046).

175 t were significantly different (P < 0.05) in BALF compared with control subjects (n = 9).

176 tamers significantly different (P < 0.05) in BALF compared with control subjects (n = 9).

177 d increases in IL-4, MIP-1beta, and MCP-1 in BALF that were more elevated (p < or = 0.05) in Tg(+) mi

178 duced amounts of matrix metalloprotease-9 in BALF and were resistant to epithelial integral membrane

179 therapy, reduced serine protease activity in BALF (elastase and cathepsin G), plasma elastase footpri

180 cient mice failed to accumulate adenosine in BALF and exhibited significantly less radiation-induced

181 gher levels of cytokines and immune cells in BALF than did Spp1(+/+) mice.

182 evels of various cytokines and chemokines in BALF were not significantly different among these 3 type

183 r hypertrophy index, and total cell count in BALF.

184 Cell counts in BALF and lung immunohistology demonstrated that eosinoph

185 Our data suggest that SP-D in BALF binds beta-glucan on B. dermatitidis, blocking BAM

186 ut soluble, active MMP-8 was not detected in BALF samples.

187 f immunomodulatory cells in vivo detected in BALF.

188 ta provide evidence that HHV-6B detection in BALF is associated with higher mortality in allogeneic h

189 Significant differences in BALF exosomal miRNA was detected for 24 miRNAs with a su

190 e fluid (BALF), and cellular distribution in BALF were then examined.

191 d CCL-20 levels were quantitated by ELISA in BALF and serum samples from 60 LTRs.

192 erential cell counts revealed eosinophils in BALF that increased (p < or = 0.05) in Tg(+) mice at 9 d

193 The miRNA-rich-EVs in BALF are likely derived from alveolar epithelial type-I

194 ntify and characterize the miRNA-rich-EVs in BALF.

195 mRNA expression in BALF cells was quantified by using TaqMan low-density ar

196 S toxin and numbers of mycoplasma genomes in BALF and the degree of histologic pulmonary inflammation

197 IL-13, and IL-5 were significantly higher in BALF of symptomatic as compared with clinically asymptom

198 Moreover, the protein levels of IL17A in BALF were also found greatly decreased in children with

199 P = 0.036) and a trend toward an increase in BALF eosinophils as compared to HDM challenge.

200 OPD exacerbations, with a 2-fold increase in BALF ferritin and iron conveying a 24% and 2-fold increa

201 n concentration was also highly increased in BALF and blood of these models with tumors.

202 Cd39(-/-) mice exhibited marked increases in BALF ATP levels but paradoxically exhibited limited AAI

203 esponse upon HDM exposure, with increases in BALF cytokines IL-17A and KC, and Th17 cytokine producin

204 l lining fluid, with associated increases in BALF IL-1beta levels.

205 ficantly attenuated cellular infiltration in BALF and allergic airway hyperresponsiveness.

206 imes and activates the NLPR3 inflammasome in BALF macrophages from asthmatic subjects to secrete IL-1

207 stin degradation (desmosine/isodesmosine) in BALF.

208 interleukin-5 and interferon-gamma levels in BALF and in OVA-incubated splenocytes.

209 nes significantly reduced IL-1beta levels in BALF during ALI.

210 Inflammatory cytokine levels in BALF from OVA-sensitized, M pneumoniae-infected or S pne

211 Thus, decreased IL17A levels in BALF may be a valuable biomarker to identify severe MPP

212 Extracellular histone and IL-1beta levels in BALF were also elevated in C5a-induced and IgG immune co

213 stone H3 tissue levels and NET-DNA levels in BALF.

214 LI) and reduced cytokine/chemokine levels in BALF.

215 nase activity and increased YKL-40 levels in BALF.

216 elated with the percentage of neutrophils in BALF (r = 0.41, P < 0.05 and r = 0.46, P < 0.05, respect

217 IL-22(+) TCRbeta(+) cells and neutrophils in BALF.

218 atment-dependent variation in neutrophils in BALF.

219 like (with an elevated level of periostin in BALF) and non-T2/proinflammatory (with higher levels of

220 more than half of the metabolites present in BALF were also present in plasma.

221 me, we detected vitamin D-binding protein in BALF exosomes, which was more abundant in patients.

222 wer ratio of kallistatin to total protein in BALF showed a significant trend toward elevated neutroph

223 orated pulmonary oedema and total protein in BALF.

224 Furthermore, eosinophil ratio in BALF was 3%, hyperplasia of goblet cell, eosinophilic in

225 ic N-ERD and correlated with T2 signature in BALF cells.

226 ed serum IL-4 and IL-17 levels and increased BALF % CD4(+) T cells that produce IL-5 and IL-13.

227 ouse lung PAFR mRNA expression and increased BALF and lung pneumococcal CFU values.

228 modelling, high BALF eosinophilia, increased BALF pro-inflammatory cytokines, reduced BALF IL-10 leve

229 The LPS + PM group showed increased BALF leukocytes, characterized by increased macrophages,

230 d to BALF exosomes from healthy individuals, BALF exosomes from asthmatics displayed higher levels of

231 increased Alt-Ext-induced IL-33 release into BALF, and ST2 deficiency decreased Alt-Ext-induced TSLP

232 en challenge, IL-33 is rapidly released into BALFs at levels that do not correlate with other immedia

233 Matched BALF and plasma was collected from mice (ambient air or

234 hILD diagnoses and control subjects.Methods: BALF was collected for clinical indications and banked i

235 Moreover, BALF-induced RelA activity was completely abolished foll

236 Mouse BALF and human BALF had a strong positive correlation wi

237 ised human cell-based assays, ex vivo murine BALF, in vivo pre-clinical models and human samples to t

238 bmGT, was detected in 71% of sera and 50% of BALF of neutropenic mice; neither was detected in serum/

239 y at acidic pH; the bactericidal activity of BALF at acidic pH was completely blocked by SP-BN Ab.

240 Multiparameter analysis of BALF mediators of all patients with asthma revealed the

241 phenotypic and functional characteristics of BALF exosomes in asthma.

242 spectrometric proteomics characterization of BALF exosomes from 15 patients with sarcoidosis and 5 he

243 ysis, to assess the bacterial composition of BALF from children with CF and disease controls (DC).

244 Hypoxemia, pulmonary edema, and levels of BALF alveolar macrophages, neutrophils, IFN-gamma, and I

245 Levels of BALF leukocytes, gamma interferon (IFN-gamma), and inter

246 where plasma may be interrogated in lieu of BALF or lung tissue.

247 ajor surface glycoprotein gene per 25 mul of BALF, corresponding to 10 to 20 P. jirovecii cells.

248 t cell degranulator, increased the number of BALF cells and bacterial burden.

249 Significantly greater mean numbers of BALF neutrophils were found in Notch3-/- and Notch4-/- m

250 In contrast, the remaining populations of BALF EVs (76% of total EVs) contain extremely low concen

251 The type-2 (T2) immune signature of BALF cells was more pronounced in the eosinophilic subph

252 SP-D was detected by anti-SP-D antibody on BALF-treated unwashed B. dermatitidis in an immunofluore

253 umonia (n=10), CXCR1 and CXCR2 expression on BALF neutrophils was higher than in controls (n=3) (medi

254 nd chemokines also were detected in serum or BALF from MIF(-/-) mice.

255 RNAs, miR-17-5p was upregulated in patients' BALF and in EVs of IAV-infected lung epithelial cells (A

256 Likewise, PLTP BALF activity levels decreased by 20 and 40% in smoke-ex

257 Pneumonic BALF, but not S. pneumoniae, induced degradation of Ikap

258 Epithelial and RBC BALF-MV are elevated at CLAD diagnosis, have a potential

259 In MS-WF-exposed mice CV-3988 reduced BALF CFU values.

260 sed BALF pro-inflammatory cytokines, reduced BALF IL-10 levels, reduced blood Tregs, increased expres

261 Cromolyn, a mast cell stabilizer, reduced BALF cells and bacterial burden similar to the levels se

262 itative bacterial culture methods on remnant BALF.

263 tropenic mice; neither was detected in serum/BALF of CGD or steroid-treated mice.

264 Similarly, BALF concentrations of periostin and CCL26 were signific

265 ORT had complementary effects and suppressed BALF and tissue eosinophils and inflammation, MSC number

266 We tested BALF for HHV-6B DNA using polymerase chain reaction in a

267 ssay experiments demonstrated that Muc5ac-Tg BALF and purified Muc5ac reduced infection, likely via b

268 ted MMP-8(-/-) mice had more MIP-1alpha than BALF from LPS-treated WT mice, but similar levels of oth

269 Furthermore, we show that BALF exosomes contain enzymes for LT biosynthesis.

270 The BALF depleted by a coating of B. dermatitidis lost the a

271 The BALF was collected from 37 LTR at time point of CLAD dia

272 The BALF-MV levels of epithelial and red blood cell (RBC) or

273 2 is released and biologically active in the BALF and can regulate airway epithelial cell cytokine ex

274 sociated with higher Gal-3 expression in the BALF as well as lung tissue.

275 ese LTRs displayed HCMV DNA detection in the BALF by PCR, whereas other infectious agents were undete

276 rived extracellular histones appeared in the BALF during ALI and directly activated the NLRP3 inflamm

277 ore than 690 proteins were identified in the BALF exosomes, several of which displayed significant up

278 Most of the HNP-1 in the BALF from individuals with a history of smoking was, in

279 ssive and non-progressive sarcoidosis in the BALF included CD28 signaling and PFKFB4 signaling.

280 er the curve (AUC) for each biomarker in the BALF of 40 lung transplant patients who had at least fou

281 Chitinase activity was greater in the BALF of asthmatics (mean, 0.85 +/- 1.2 U/mL) compared wi

282 ise YKL-40 concentrations were higher in the BALF of asthmatics and correlated with chitinase activit

283 towards increased fungal-specific IgG in the BALF of asthmatics compared with non-asthmatics and for

284 oformans and A. fumigatus was greater in the BALF of asthmatics compared with non-asthmatics.

285 and IgA reactivity to fungal proteins in the BALF of asthmatics may reflect a local response to funga

286 ntified 1115 high confidence proteins in the BALF out of which 142 were differentially expressed betw

287 dings demonstrating early differences in the BALF protein expression in ARDS survivors vs. non-surviv

288 F), protein and CINC-1 concentrations in the BALF, and the lung histology.

289 In the BALF, the differentially expressed proteins map to sever

290 phil recruitment, and myeloperoxidase in the BALF.

291 pproximately 39% of the total EV RNAs in the BALF.

292 by small sample size in the mouse study, the BALF metabolome appeared to be more affected by CS than

293 educed inflammatory cytokine levels in their BALF, and reduced levels of morbidity relative to animal

294 Compared to BALF exosomes from healthy individuals, BALF exosomes fr

295 tion of clodronate effectively reduced total BALF cell numbers, CCR2(+) immature macrophages, and eos

296 A unique BALF lymphocyte profile was associated with rejection an

297 robial activity, B. dermatitidis may utilize BALF constituents, such as SP-D, to blunt the host defen

298 Thus, whereas BALF constituents commonly mediate antimicrobial activit

299 Comparison with BALF from controls identifies a critical imbalance in RA

300 B. dermatitidis incubated with BALF and washed, plus BAM, stimulated 63% less productio