ライフサイエンスコーパス: C-C chemokine

1 ls are a rich source of eosinophil-selective C-C chemokines.

2 nd decrease in the production of a number of C-C chemokines.

3 y on the discrete target cell selectivity of C-C chemokines.

4 xodus-2 also had unusual characteristics for C-C chemokines.

5 n vivo chemoattractant activity of different C-C chemokines.

6 alternative macrophage activation-associated C-C chemokine (AMAC) 1, or dendritic cell-derived C-C ch

7 Up-regulation of the three C-C chemokines and down-modulation of cell surface CCR5

8 othelial cells (PMC) to release C-X-C and/or C-C chemokines and express adhesion molecules that initi

9 the mammalian enzyme, fungal DppIVA cleaved C-C chemokines and GM-CSF.

10 cells from normal and HIV-1+ donors produce C-C chemokines and other unidentified factors that can i

11 The data suggest that a dual mechanism of C-C chemokines and specific Abs may engage and down-modu

12 showed distinct differences in expression of C-C chemokines and their receptors between children with

13 We hypothesized that IL-2 alters cytokine, C-C chemokine, and adhesion molecule expression in assoc

14 ot rendered susceptible by neutralization of C-C chemokines, and addition of C-C chemokines did not c

15 matory protein-1alpha (MIP-1alpha) and other C-C chemokines, and that addition of anti-CD28 gives ver

16 C-C chemokines are a structurally defined family of chem

17 These data indicate that multiple C-C chemokines are involved in the recruitment of partic

18 The C-C chemokines are major mediators of chemotaxis of mono

19 RS is overproduction of eosinophil-promoting C-C chemokines by sinus epithelium, perhaps driven in pa

20 Previous studies have suggested that the C-C chemokine C10 is involved in the chronic stages of h

21 Unlike other C-C chemokines, C10 levels in the peritoneal wash were i

22 the tumor microenvironment (TME) through the C-C chemokines CCL17 and CCL22.

23 hemokine (AMAC) 1, or dendritic cell-derived C-C chemokine (DCCK) 1).

24 alization of C-C chemokines, and addition of C-C chemokines did not consistently suppress endogenous

25 haracterized by elevated IgE, Th2 cytokines, C-C chemokines, eosinophilic inflammation, and persisten

26 The C-C chemokine eotaxin is a potent chemoattractant for eo

27 on in response to i.p. administration of the C-C chemokine, eotaxin, was studied in vivo.

28 We show that the C-C chemokines, eotaxin and RANTES (regulated upon activ

29 Up-regulation of C-C chemokine expression characterizes allergic inflamma

30 that Th1 and Th2 cytokines may regulate the C-C chemokine expression in PMCs and thus play a biologi

31 dy, we examined the effect of MIP-1 gamma, a C-C chemokine family member, on receptor activator of NF

32 the present study, we present data that the C-C chemokine family members may be a factor influencing

33 ng site regulation of MCP-1, a member of the C-C chemokine family, in a rat model of volume-overload

34 RANTES, a member of the C-C chemokine family, is a potent chemoattractant for T

35 biological activities for this member of the C-C chemokine family.

36 Th2 cells may induce selective production of C-C chemokines from epithelium and indicate that glucoco

37 xamine lung tissue for expression of CXC and C-C chemokine genes and bronchoalveolar lavage (BAL) flu

38 to aerosolized OVA has been used to identify C-C chemokine genes expressed at stages of massive eosin

39 lted in increased expression of both CXC and C-C chemokines genes in lung tissues.

40 osinophil activation; however, mRNA for this C-C chemokine has been shown to be constitutively expres

41 Hemofiltrate C-C chemokine (HCC)-1 is a recently cloned C-C chemokine

42 The C-C chemokines human monocyte chemoattractant protein-1

43 nflammation with increases in Th2 cytokines, C-C chemokines, IgE production, and mucous cell metaplas

44 M challenge with increases in Th2 cytokines, C-C chemokines, IgE production, and mucous cell metaplas

45 Eotaxin is a C-C chemokine implicated in the recruitment of eosinophi

46 od mononuclear cells (CBMC) to secrete these C-C chemokines in comparison to adult blood mononuclear

47 The CCR5 Abs were complementary to the C-C chemokines in inhibiting HIV replication in vitro.

48 Binding assays using 125I-labeled C-C chemokines in mammalian cells indicated that CHEMR1

49 CD4-specific chemoattractant, and RANTES, a C-C chemokine, in response to GD-specific IgG (GD-IgG).

50 hocyte chemoattractant, IL-16, and RANTES, a C-C chemokine, in their fibroblasts.

51 Three C-C chemokines inhibit human immunodeficiency virus (HIV

52 TCA3, a C-C chemokine, is produced by Ag-activated T cells and i

53 e of the monocyte chemotactic and activating C-C chemokine JE/monocyte chemotactic protein-1 has been

54 Among C-C chemokines known to chemoattract different leukocyte

55 cytokines with myelogenic potential such as C-C chemokine ligand (CCL)2, interleukin (IL)-6, and VEG

56 haracterize the homologues of human eotaxin (C-C chemokine ligand 11) and CCR3 from other species, su

57 cardiomyocyte ablation to investigate CCL17 (C-C chemokine ligand 17).

58 taxis requires either of the cognate ligands C-C chemokine ligand 19 (CCL19) or CCL21.

59 ey identify the T-cell activation regulators C-C chemokine ligand 19 and C-C chemokine receptor 7 as

60 t obesity activates hepatocyte expression of C-C chemokine ligand 2 (CCL2/MCP-1) leading to hepatic r

61 igh) monocytes accrue in response to a brief C-C chemokine ligand 2 burst.

62 eus, presumably via a mechanism of decreased C-C chemokine ligand 2 levels in the cerebrospinal fluid

63 of PDGFR-B(+) cells via a Forkhead box M1 to C-C chemokine ligand 2-receptor 2 pathway.

64 We identified C-C chemokine ligand 20 (CCL20) and tumor necrosis facto

65 ate the role of the C-C chemokine receptor 6/C-C chemokine ligand 20 (CCR6/CCL20) chemokine axis in m

66 CCL17 activated Gq signaling and CCL22 (C-C chemokine ligand 22) activated both Gq and ARRB (bet

67 Several N-terminally engineered analogs of C-C chemokine ligand 5 (CCL5), a natural ligand of CCR5,

68 This study shows that potent C-C chemokine ligand 5 analogs differ from each other an

69 ion in many inflammatory chemokines, such as C-C chemokine ligand 5, CXC ligand 9 (CXCL9), and CXCL10

70 TNF-deficient mice had reduced expression of C-C chemokine ligand 5, CXCL9, and CXCL10 at early time

71 (+)Flk1(+) circulating angiogenic cells in a C-C chemokine ligand 5/C-C chemokine receptor 5-dependen

72 h ALD, and increased circulating chemokines, C-C chemokine ligand types 2 (CCL2), and C-C chemokine l

73 es, C-C chemokine ligand types 2 (CCL2), and C-C chemokine ligand types 5 (CCL5) in patients with alc

74 Protein levels of C-C chemokine ligand-2 (CCL-2)/monocyte chemotactic prot

75 but not TGF-beta2 or TGF-beta3, and elevated C-C chemokines macrophage chemoattractant protein-1, mac

76 e, macrophage inflammatory protein-2 and the C-C chemokines macrophage inflammatory protein-1alpha an

77 ivity by induction of the cysteine-cysteine (C-C) chemokine macrophage inflammatory protein 1beta (MI

78 evated immunohistochemical expression of the C-C chemokines, macrophage inflammatory protein-1 alpha

79 chemokine GRO alpha and the mononuclear cell C-C chemokines: macrophage inflammatory protein 1 alpha,

80 ar cells may be critical effector cells, and C-C chemokines may play important roles in the initiatio

81 Lung mRNA expression of the C-C chemokine MCP-1 was increased in OVA-indomethacin mi

82 These results suggest that the production of C-C chemokines (MCP-1 or MIP-1 alpha) during an immune r

83 this considerable sequence homology to other C-C chemokines, MCP-2 appears to have unique functional

84 1, but had only minor effects on the related C-C chemokines MIP-1 alpha and RANTES.

85 The C-C chemokines MIP-1alpha, MIP-1beta, and RANTES have be

86 Importantly, the C-C chemokines MIP-1alpha, MIP-1beta, and RANTES were re

87 To elucidate the role of C-C chemokines, MIP-1 alpha and MCP-1, we have used both

88 The C-C chemokine monocyte chemoattractant protein-1 (MCP-1)

89 phage inflammatory protein-2, as well as the C-C chemokines murine monocyte chemoattractant protein-1

90 at CHEMR1 may be a receptor for unidentified C-C chemokine or a low-affinity receptor for MIP-1alpha.

91 demonstrating that mesothelial cell-derived C-C chemokines play a biologically important role in the

92 Thus, although C-C chemokines play a broad role in influencing inflamma

93 C-C chemokines play an important role in recruitment of

94 We studied the regulation of C-C chemokine production by CD28 costimulatory signals b

95 uency of resistant cultures without reducing C-C chemokine production.

96 The C-C chemokines RANTES, MIP-1 alpha and MIP-1 beta were r

97 but was associated with the activity of the C-C chemokines RANTES, MIP-1alpha, and MIP-1beta.

98 tion, and could be neutralized by removal of C-C chemokines (RANTES (regulated upon activation, norma

99 f PBM and AM increases the production of the C-C chemokine, RANTES.

100 The recently discovered C-C chemokines, RANTES (regulated on activation, normal

101 The three C-C chemokines, RANTES, macrophage-inflammatory protein-

102 madeltaT cells are recruited to the liver by C-C chemokine receptor (CCR) 2, CCR5, and nucleotide-bin

103 t protein (MCP) 1 are mediated by binding to C-C chemokine receptor (CCR) 2.

104 Here we show that ligation of the C-C chemokine receptor (CCR) 5 can provide a major signa

105 The frequency of homozygous C-C chemokine receptor (CCR) 5- Delta 32 was higher in E

106 l major histocompatibility complex class II, C-C chemokine receptor (CCR) type 1, CCR2, CX3C chemokin

107 f chemokine (C-C motif) ligand (CCL)2, CCL4, C-C chemokine receptor (CCR)1, and CCR5, which are invol

108 s revealed that HCC-1 specifically activated C-C chemokine receptor (CCR)1, but not closely related r

109 8(-) T cells were activated CD69(+)CD45RA(-) C-C chemokine receptor (CCR)7(-) effector memory and per

110 has been shown to increase the production of C-C chemokine receptor (CCR5)-binding chemokines under c

111 The C-C chemokine receptor (CCR7) G protein-coupled receptor

112 C-C chemokine receptor 1 (CCR1) is a chemokine receptor

113 study addressed the role of their receptor, C-C chemokine receptor 1 (CCR1), in this model.

114 NAME-treated mice expressed higher levels of C-C chemokine receptor 2 (CCR2) and CCR3 mRNA and contai

115 and studies have demonstrated that the MCP-1/C-C chemokine receptor 2 (CCR2) axis might be involved i

116 ated with single nucleotide polymorphisms of C-C chemokine receptor 2 (CCR2) gene.

117 C-C chemokine receptor 2 (CCR2) is a dual-function recep

118 C-C chemokine receptor 2 (CCR2) is a key driver of monoc

119 This study evaluated whether C-C Chemokine Receptor 2 (CCR2) is a tissue biomarker of

120 C-C chemokine receptor 2 (CCR2) is considered the major

121 tic steatosis in obese mice deficient in the C-C chemokine receptor 2 (CCR2) that regulates myeloid c

122 Changes in MCP-1, C-C chemokine receptor 2 (CCR2), procollagen I and III,

123 generate mice with a targeted disruption of C-C chemokine receptor 2 (CCR2), the receptor for MCP-1.

124 ote inflammation, it remains unclear whether C-C chemokine receptor 2 (CCR2)- and Ly6C-expressing inf

125 C-C chemokine receptor 5 (CCR5)-Delta 32 and C-C chemokine receptor 2 (CCR2)-64I (relative hazard = 0

126 We investigated the role of C-C chemokine receptor 2 (CCR2)-dependent cell recruitme

127 elosuppressive chemokine, specifically binds C-C chemokine receptor 2 (CCR2).

128 inducible nitric oxide synthase (iNOS), and C-C chemokine receptor 2 (CCR2).

129 that the monocyte chemoattractant protein-1/C-C chemokine receptor 2 axis plays a critical role in t

130 high) monocytes express heightened levels of C-C chemokine receptor 2 on their surface, avidly infilt

131 Expression of the chemokine receptor C-C Chemokine Receptor 2 was reduced on CD4 central memo

132 Monocyte chemoattractant protein-1 and C-C chemokine receptor 2 were increased in the tissues f

133 or monocyte chemoattractant protein (MCP)-1, C-C chemokine receptor 2(CCR2), interleukin (IL)-1beta,

134 d the functional relevance of donor CCR2(+) (C-C chemokine receptor 2) and CCR2(-) macrophages using

135 t distinct subsets of tissue-resident CCR2- (C-C chemokine receptor 2) and CCR2+ macrophages orchestr

136 Wild-type animals that received C-C chemokine receptor 2-deficient bone marrow had a com

137 Compared with MMR- and C-C chemokine receptor 2-deficient mice, significantly h

138 C-C chemokine receptor 2-deficient recipients of GFP-exp

139 the human thrombin receptor (PAR-1) and the C-C chemokine receptor 2B.

140 The C-C chemokine receptor 3 (CCR3) is dramatically upregula

141 The beta-chemokine receptor C-C chemokine receptor 3 (CCR3) provides a mechanism for

142 etreatment of eosinophils with an mAb to the C-C chemokine receptor 3 (CCR3).

143 We found that HIV-1 coat proteins that used C-C chemokine receptor 3 or C-X-C chemokine receptor 4 a

144 and activated blood basophils overexpressing C-C chemokine receptor 3.

145 The C-C chemokine receptor 4 (CCR4) is broadly expressed on

146 ansplantation (alloHSCT) from donors lacking C-C chemokine receptor 5 (CCR5(Delta32/Delta32)) can cur

147 odifications of the chemokine RANTES bind to C-C chemokine receptor 5 (CCR5) and block human immunode

148 C-C chemokine receptor 5 (CCR5) has been implicated in t

149 We have shown that mice that express the C-C chemokine receptor 5 (CCR5) have enhanced local tumo

150 ptors C-X-C chemokine receptor 3 (CXCR3) and C-C chemokine receptor 5 (CCR5) in establishing type 1 i

151 kout studies demonstrated the involvement of C-C chemokine receptor 5 (CCR5) in NK cell recruitment a

152 his study, we demonstrate a crucial role for C-C chemokine receptor 5 (CCR5) in the accelerated recru

153 C-C chemokine receptor 5 (CCR5) is a chemokine receptor

154 C-C chemokine receptor 5 (CCR5) is a key drug target for

155 s used a B16-F10 melanoma model to show that C-C chemokine receptor 5 (CCR5) knockout (CCR5(-/-)) mic

156 , we evaluated whether the disruption of the C-C chemokine receptor 5 (CCR5) locus in pigtailed macaq

157 anonical amino acids with reactive groups in C-C chemokine receptor 5 (CCR5) near an allosteric bindi

158 to CD4 followed by engagement of either the C-C chemokine receptor 5 (CCR5) or C-X-C chemokine recep

159 The C-C chemokine receptor 5 (CCR5) plays a crucial role in

160 C-C chemokine receptor 5 (CCR5) plays an essential role

161 C-C chemokine receptor 5 (CCR5), a member of G-protein-c

162 We tested this hypothesis for C-C chemokine receptor 5 (CCR5), a molecule involved in

163 k of a protective genotype, consisted of: 1) C-C chemokine receptor 5 (CCR5)-Delta 32 and C-C chemoki

164 ites in a G protein-coupled receptor (GPCR), C-C chemokine receptor 5 (CCR5).

165 angiogenic cells in a C-C chemokine ligand 5/C-C chemokine receptor 5-dependent manner.

166 viral load and could be traced to a single, C-C chemokine receptor 5-tropic founder virus with short

167 ntal autoimmune encephalomyelitis (EAE), the C-C chemokine receptor 6 (CCR6) is critical for pathogen

168 CCL20 (C-C motif chemokine ligand 20)-CCR6 (C-C chemokine receptor 6) axis for formation of new vess

169 of IL17A, IL17F, retinoid-orphan-receptor C, C-C chemokine receptor 6, and the IL23 receptor.

170 his study was to investigate the role of the C-C chemokine receptor 6/C-C chemokine ligand 20 (CCR6/C

171 We hypothesized that chemokine receptors C-C chemokine receptor 7 (CCR7) and C-X-C chemokine rece

172 cells carry out immune functions, using the C-C chemokine receptor 7 (CCR7) and its cognate ligands,

173 Gene expression analysis exposed upregulated C-C chemokine receptor 7 (CCR7) and its ligand CCL21 in

174 ulates CXCR5 but not Bcl6, and downregulates C-C chemokine receptor 7 (CCR7) expression in T cells in

175 C-C chemokine receptor 7 (CCR7) facilitates entry of T c

176 (+) adipose tissue immune cells that express C-C chemokine receptor 7 (CCR7) in mice and humans, and

177 ation regulators C-C chemokine ligand 19 and C-C chemokine receptor 7 as potential mediators of immun

178 T(reg) cells expressing the C-C chemokine receptor 8 (CCR8) have been associated wit

179 Expression of either human or simian C-C chemokine receptor CCR5 allowed the SIVmac239 envelo

180 The C-C chemokine receptor CCR5 in humans and rhesus macaque

181 The C-C chemokine receptor CCR5 serves an important function

182 C-X-C chemokine receptor type 4 (CXCR4) and C-C chemokine receptor type 1 (CCR1), which are the rece

183 4)/chemokine (C-C motif) ligand 5 (CCL5) and C-C chemokine receptor type 1 (CCR1)/C-C chemokine recep

184 Moreover, M2a hMd s express several CCRI (C-C chemokine receptor type 1) ligands.

185 -C motif) ligand 28 (CCL28) and its receptor C-C chemokine receptor type 10 (CCR10) in downregulation

186 frequency of MO, T cells, and expression of C-C chemokine receptor type 2 (Ccr2) and C-C chemokine r

187 Upstream to Fyn, MCP1 stimulated C-C chemokine receptor type 2 (CCR2) and Gi/o and inhibi

188 C-C chemokine receptor type 2 (CCR2) and its ligands (CC

189 C-C chemokine receptor type 2 (CCR2) antagonist and clod

190 The monocyte chemoattractant protein (MCP-1)/C-C chemokine receptor type 2 (CCR2) axis critically reg

191 A comparison of the MCP-1/C-C chemokine receptor type 2 (CCR2) chemokine system be

192 ptic burned patients with a special focus on C-C chemokine receptor type 2 (CCR2) expressions on clas

193 C-C chemokine receptor type 2 (CCR2) is expressed by act

194 C-C chemokine receptor type 2 (CCR2) is expressed on mon

195 iptomics predicted that interactions between C-C chemokine receptor type 2 (CCR2) macrophages and fib

196 d whether CCX140-B, a selective inhibitor of C-C chemokine receptor type 2 (CCR2), could further redu

197 nstants of C-C motif chemokine 7 (CCL7) with C-C chemokine receptor type 2 (CCR2), monosulfated CCR2,

198 The generated MDSC were expressed C-C chemokine receptor type 2 (CCR2), which was enhanced

199 s and chemokinesis of cancer cells via their C-C chemokine receptor type 2 (CCR2), with no notable ch

200 C-C chemokine receptor type 2 (CCR2)-dependent monocyte

201 A C-C chemokine receptor type 2 (CCR2)-positive macrophage

202 lating factor 1 receptor blockade diminished C-C chemokine receptor type 2 [CCR2(neg) (Ly6C(lo))] mon

203 2 expression and higher plasma levels of the C-C chemokine receptor type 2 chemokine (C-C motif) liga

204 ts with LOY >17% showed significantly higher C-C chemokine receptor type 2 expression and higher plas

205 levels (P=0.024) at 2-day post MI, decreased C-C chemokine receptor type 2 expression in monocytes (P

206 d macrophage-1 receptor, Sialil-Lewis X, and C-C chemokine receptor type 2 expression in monocytes.

207 , especially within the hemoglobin delta and C-C chemokine receptor type 2 genes, respectively, causi

208 s and led to a higher proportion of CCR2(+) (C-C chemokine receptor type 2 positive) macrophages.

209 The C-C chemokine receptor type 2 protein (CCR2) functions i

210 fingolimod (FTY720)-sensitive manner and use C-C chemokine receptor type 2 to accumulate in inflamed

211 ilencing of the monocyte-recruiting receptor C-C chemokine receptor type 2 with short-interfering RNA

212 Macrophage depletion in CCR2 (C-C chemokine receptor type 2) knockout mice showed that

213 ns, the heart is largely populated by CCR2- (C-C chemokine receptor type 2) macrophages of embryonic

214 Recent studies have established that CCR2 (C-C chemokine receptor type 2) marks proinflammatory sub

215 th the accumulation of Spp1-expressing CCR2 (C-C chemokine receptor type 2)(+) cardiac resident macro

216 We observed marked increases in CCR2 (C-C chemokine receptor type 2)(+) monocyte-derived macro

217 of five GPCRs (cannabinoid receptor type 1, C-C chemokine receptor type 2, M2 muscarinic receptor, P

218 rage in adipocytes in a leptin receptor- and C-C chemokine receptor type 2-independent manner.

219 d IL-13 receptor alpha1 and donor eosinophil C-C chemokine receptor type 3 (CCR3) and interleukin 1 r

220 creased IL-5 and IL-13 expression as well as C-C chemokine receptor type 3 expression in the sputum o

221 To determine the role of its receptor CCR3 (C-C chemokine receptor type 3) in fibroblast activation,

222 for this activation, and the combination of C-C chemokine receptor type 4 (CCR4) chemokine receptors

223 By reducing CCL22 binding to C-C chemokine receptor type 4 on Tregs, microRNA-15a/16-

224 ges was correlated with the number of dermal C-C chemokine receptor type 4(+) T helper type 2 cells,

225 C-C chemokine receptor type 5 (CCR5) antagonists may imp

226 -inhibitor T20 (Fuzeon, enfuvirtide) and the C-C chemokine receptor type 5 (CCR5) blocker maraviroc (

227 of C-C chemokine receptor type 2 (Ccr2) and C-C chemokine receptor type 5 (Ccr5) in the livers of pa

228 The C-C chemokine receptor Type 5 (CCR5) is a key receptor f

229 CRISPR-Cas9-mediated gene editing at the C-C chemokine receptor type 5 (CCR5) locus was used to f

230 r studies demonstrated that ORM1 can bind to C-C chemokine receptor type 5 (CCR5) on muscle cells and

231 tly in the human leukocyte antigen (HLA) and C-C chemokine receptor type 5 (CCR5) regions-explains 25

232 C-C chemokine receptor type 5 (CCR5) serves as a co-rece

233 ying rilpivirine (RPV) is decorated with the C-C chemokine receptor type 5 (CCR5) targeting peptide.

234 ficantly higher prechallenge levels of CD4(+)C-C chemokine receptor type 5 (CCR5)(+)HLA-DR(+) T cells

235 s (NP) to deliver Maraviroc, an inhibitor of C-C chemokine receptor type 5 (CCR5), a CCL3 receptor.

236 mportance of the G-protein-coupled receptor, C-C chemokine receptor type 5 (CCR5), in human disease s

237 L5) and C-C chemokine receptor type 1 (CCR1)/C-C chemokine receptor type 5 (CCR5), the receptors for

238 ayed (12-24 h) increase in the expression of C-C chemokine receptor type 5 (CCR5)-an immune receptor

239 Individuals homozygous for the C-C chemokine receptor type 5 gene with 32-bp deletions

240 tems targeting the human hemoglobin beta and C-C chemokine receptor type 5 genes have substantial off

241 chemokine (C-C motif) ligand 5 that binds to C-C chemokine receptor type 5 on BCCs and BCCs secrete c

242 Leronlimab, a monoclonal antibody blocker of C-C chemokine receptor type 5 originally developed to tr

243 While frequencies of foreskin C-C chemokine receptor type 5(+) (CCR5(+)) T cells, T re

244 udied zinc finger nucleases (ZFNs) targeting C-C chemokine receptor type 5.

245 C-C chemokine receptor type 7 (CCR7) expression on infus

246 ation and expression of the migration marker C-C chemokine receptor type 7 (CCR7) in PGN-stimulated c

247 ode-homing molecules CD62 ligand (CD62L) and C-C chemokine receptor type 7 (CCR7), which are expresse

248 ypothesized that an age-related reduction in C-C chemokine receptor type 7 (CCR7)-dependent egress of

249 The C-C chemokine receptor type 9 (CCR9) coordinates immune

250 rilpivirine was followed by dual CRISPR-Cas9 C-C chemokine receptor type five (CCR5) and HIV-1 provir

251 olling (CD14dimCD16(+)) monocytes, and their C-C chemokine receptor type-2 (CCR2) expression were qua

252 The C-C chemokine receptor, CCR2, has been identified as the

253 One C-C chemokine receptor, CCR2, has been identified that m

254 chemotaxis is mediated primarily through the C-C chemokine receptor, CCR3.

255 We have cloned a novel murine C-C chemokine receptor, designated mouse CCR2 (mCCR2), f

256 The C-C chemokine receptor-1 (CKR-1), the MCP-1 receptor-A (

257 (Ccl-2; also known as MCP-1) or its cognate C-C chemokine receptor-2 (Ccr-2) develop cardinal featur

258 e interleukin-4 receptor, and recruitment of C-C chemokine receptor-2-positive monocytes and alternat

259 1alpha) receptor gene Scya3r and two related C-C chemokine receptor-like genes reside.

260 used ApoE-/-OPN-/- mice expressed less CD68, C-C-chemokine receptor 2, and VCAM-1.

261 HIV-1 strains use C-C-chemokine receptor 5, CCR5, as a coreceptor for host

262 th the technetium-99m-6-hydrazinylnicotinoyl-C-C-chemokine receptor-2 ligand ((99m)Tc-HYNIC-CCR2-L).

263 RA) joint, we investigated the expression of C-C chemokine receptors (CCR) 1-6 and C-X-C receptor 3 (

264 Fibronectin, C-C chemokine receptors (CCRs)2 and 7, and oxidative str

265 The pathways by which the C-C chemokine receptors activate phospholipase C (PLC) w

266 icant functional differences between the two C-C chemokine receptors and suggest a two-step mechanism

267 In experiments using cells transfected with C-C chemokine receptors, 125I-MCP-2 bound to human embry

268 but not to Galpha16, suggesting some of the C-C chemokine receptors, unlike the C-X-C chemokine rece

269 ones that encode two closely related, murine C-C chemokine receptors.

270 , interferon-gamma, [IFN-gamma], and IL-12), C-C chemokines (regulated upon activation, normal T cell

271 emotactic protein (MCP)-2 is a member of the C-C chemokine subfamily, which shares more than 60% sequ

272 nctional properties in comparison with other C-C chemokines such as MCP-1 and MCP-3.

273 Levels of C-C chemokines such as monocyte chemoattractant protein-

274 characterization of a novel murine and human C-C chemokine termed Exodus-2 for its similarity to Exod

275 e C-C chemokine (HCC)-1 is a recently cloned C-C chemokine that is structurally similar to macrophage

276 hemoattractant protein-1 is one of the major C-C chemokines that has been implicated in liver injury.

277 hat MCP-2 may share the receptors with these C-C chemokines, the actual functional receptors for MCP-

278 ocyte chemoattractant protein-1 (MCP-1) is a C-C chemokine thought to play a major role in recruiting

279 In this study, the ability of several C-C chemokines to induce transendothelial migration (TEM

280 tural basis for pleiotropic signaling of the C-C chemokine type 5 (CCR5) G protein-coupled receptor (

281 llograft RNA expression of several C-X-C and C-C chemokines was tested during rejection of full thick

282 ase in eotaxin, a potent eosinophil-specific C-C chemokine, was also observed during fibroblast-mast

283 When the two C-C chemokines were individually co-incubated with Con-A

284 n and cloning of a cDNA that encodes a mouse C-C chemokine with 68% amino acid identity to guinea pig

285 inflammatory protein 1alpha (MIP-1alpha), a C-C chemokine with monocyte chemoattractant capability,

286 ctic protein-4 (MCP-4) is a newly identified C-C chemokine with potent eosinophil chemoattractant pro