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1 imer equilibrium associated with its unusual C-terminal extension.
2 packaged DyP interacts with Enc via a unique C-terminal extension.
3 tuberculosis DyP (Mt-DyP), which contains a C-terminal extension.
4 ant active site loop alterations and a large C-terminal extension.
5 ucture of the higher eukaryote specific RPC5 C-terminal extension.
6 RT folding by interacting with both TRBD and C-terminal extension.
7 he rare amino acid selenocysteine (Sec) on a C-terminal extension.
8 domains, box A and box B, and a lysine-rich C-terminal extension.
9 , while the short isoform (BRD4S) lacks this C-terminal extension.
10 e disparately affected by dimeric LC8 with a C-terminal extension.
11 cting together with a functionally important C-terminal extension.
12 rthologs are notable for their highly acidic C-terminal extension.
13 N-1 consists of a nuclease core domain and a C-terminal extension.
14 ely 15 A) from the flavin chromophore in the C-terminal extension.
15 de spanning the transmembrane region and its C-terminal extension.
16 ctivity included the leucine-rich repeat and C-terminal extension.
17 drophobic sterol-binding pocket and a unique C-terminal extension.
18 ite effects were observed on deletion of the C-terminal extension.
19 by an N-terminal extension and followed by a C-terminal extension.
20 3 (FSD3) apparently linked to binding of the C-terminal extension.
21 d hCenexin1 variant 1, that possess a unique C-terminal extension.
22 icted to adopt a HMG fold, and a lysine-rich C-terminal extension.
23 ains hydrophobic residues clustered near the C-terminal extension.
24 cturally unique secretory PLA(2) with a long C-terminal extension.
25 hing studies and antibody recognition of the C-terminal extension.
26 top codon and production of a protein with a C-terminal extension.
27 ongation is affected mainly by the length of C-terminal extension.
28 changes of the central beta hairpin and the C-terminal extension.
29 within a fragment encompassing ABS2 and the C-terminal extension.
30 inding of the second messenger c-di-GMP to a C-terminal extension.
31 15 A apart and separated by residues in the C'-terminal extension.
32 vity and is flanked on either side by N- and C-terminal extensions.
33 es through the LOV domain core to the N- and C-terminal extensions.
34 ch is flanked by variable, disordered N- and C-terminal extensions.
35 OB-fold present in bacterial IF1 plus N- and C-terminal extensions.
36 , leading to the expression of proteins with C-terminal extensions.
37 a helical motif flanked by disordered N- and C-terminal extensions.
38 terdomain insertion (4-helical bundle) and a C-terminal extension (3-helical bundle) and it packs as
43 ogues form heteromultimers and indicate that C-terminal extensions alter virus recognition by multime
44 rearrangement due to the removal of the pD1 C-terminal extension, altering the Psb27-CP43 binding in
45 The helicase core of each protein precedes a C-terminal extension and a basic tail, whose structural
46 rom similar and diverse origins highlights a C-terminal extension and a pi-cation interaction within
47 tants with deletions of N-terminal domain or C-terminal extension and also with deamidation plus abov
48 ses an immunoglobulin fold flanked by a long C-terminal extension and an N-terminal hairpin loop.
50 o somatic centrosomes via a variant-specific C-terminal extension and recruits Plk1 through a Cdc2-de
51 translational quality control prevents C-I30 C-terminal extension and rescues mitochondrial and neuro
52 We demonstrate here that processing of the C-terminal extension and sequences at the C-terminus of
53 in became water insoluble on the deletion of C-terminal extension and subsequent deletions of the C-t
55 structure reveals contacts between the Cdc34 C-terminal extension and Ub that stabilize Cdc34~Ub in a
56 vements are largest on datasets containing N/C-terminal extensions and on datasets containing long an
57 amino acid residues flanked by varied N- and C-terminal extensions and usually exist as oligomers.
58 rge subunit, endoproteolytic cleavage of the C-terminal extension, and dimerization with the small su
59 oforms: the calmodulin-binding sequence, the C-terminal extension, and the autoregulatory loop in the
60 proach by tracking the effects of mutations, C-terminal extensions, and ribosomal tethering on the st
63 , Phe(116), Val(118), and Tyr(119)) near the C-terminal extension are responsible for these activitie
66 tic functions of Rny1 are independent of the C-terminal extension, are affected by many mutations in
67 icate that these elements, together with the C-terminal extension, are involved in scaffold formation
68 This points to an important role for the C-terminal extension, Arg-163 in particular, and no sign
72 arrel core, it possesses unstructured N- and C-terminal extensions bearing several highly conserved a
73 264 amino acid fragment contains the entire C-terminal extension beginning after the EF-Tu-homologou
74 f II + connecting peptide [betaB1(149-252)], C-terminal extension [betaB1(1-234)], C-terminal extensi
76 ng NMR spectroscopy, we now show that N- and C-terminal extensions beyond the predicted C2B domain co
78 orm activase to form a disulfide bond in the C-terminal extension (C-extension) significantly increas
80 f RNA polymerase II (RNA pol II) is its long C-terminal extension, called the carboxy-terminal domain
82 complex, in which the acidic residues of the C-terminal extension cannot interact with the heparin-bi
83 ucleotide (FAD) cofactor, and a cryptochrome C-terminal extension (CCT), which is essential for signa
85 of CfaE, the CFA/I adhesin, incorporating a C-terminal extension comprising a flexible linker and 10
88 s lack TMBS2 and half of ABS1, and present a C-terminal extension containing a proline-rich domain an
89 ning the tetramer after its assembly but the C-terminal extension contributes to the overall stabilit
92 es in homodimerization and the impact of the C-terminal extension (CTE) by contrasting HP1a to its pa
93 minal GTPase domain and, except for Cdc10, a C-terminal extension (CTE) containing a predicted coiled
94 tumefaciens VirE2 and VirD2 proteins and the C-terminal extension (CTE) domain of Arabidopsis thalian
95 ified guanosine-binding "AT-hook" within the C-terminal extension (CTE) flanking the DBD, which makes
96 RNA, as in other DEAD-box proteins, while a C-terminal extension (CTE) induces a second bend, result
98 is minor groove interaction is mediated by a C-terminal extension (CTE) of the DNA binding domain and
99 onsiveness to HMGB-1/-2 was dependent on the C-terminal extension (CTE) region of the ER DNA binding
100 ls that this selectivity is dependent on the C-terminal extension (CTE), amino acid sequences adjacen
103 cess generate aberrant proteins with unusual C-terminal extensions (CTEs) that promote aggregation an
104 nts and deamidated plus N-terminal domain or C-terminal extension deleted mutants: (i) alphaA-NT (NT,
105 (iv) alphaA-N101/123D-NT, (v) alphaA-CT (CT, C-terminal extension deleted), (vi) alphaA-N101D-CT, (vi
106 nd that the 25 residues comprising the novel C-terminal extension do not participate in receptor acti
107 tch of pentatricopeptide repeats (PPR) and a C-terminal extension domain ending with the amino acids
109 6SS effectors consists of VgrG proteins with C-terminal extension domains carrying various enzymatic
110 site of post-transfer editing, or the N- or C-terminal extension domains of eukaryotic and archaeal
113 ably the lack of TMBS2 and the presence of a C-terminal extension featuring a proline-rich domain and
116 st two zinc fingers, whereas residues in the C-terminal extension following the third zinc finger bin
117 hemical studies proved the importance of the C-terminal extension for MgCh stimulation and inactivati
118 dopts an extended conformation, exposing the C-terminal extension for prenylation or enabling OsCaM61
120 tic of C2 domains and that the unique N- and C-terminal extensions form a small subdomain that packs
121 ously reported analogs and relies on the HPF C-terminal extension forming the binding platform for th
124 he structural mechanisms by which its unique C-terminal extension functions in Cdc34 activity are unk
127 inter alia by introducing HbYX, RYX, or RHbX C-terminal extensions (Hb, hydrophobic moiety; R, argini
128 r eukaryotes, PNGase has an N-terminal and a C-terminal extension in addition to its central catalyti
129 ed form of Rv2466c revealed the binding of a C-terminal extension in alpha-helical conformation to a
131 demonstrate the intrinsic flexibility of the C-terminal extension in CDK12 and highlight its importan
132 these two stealth family proteins revealed a C-terminal extension in CsxA, which conferred processivi
133 Aquifex aeolicus (Aacpn10) has a 25-residue C-terminal extension in each monomer not found in any ot
136 phaB-crystallin increased on deletion of the C-terminal extension in the deamidated alphaA mutants, b
138 ons among NADP (+), FAD, and residues in the C'-terminal extension indicate that the gross conformati
139 pha-crystallin domain with disordered N- and C-terminal extensions, indicating that the extensions ar
142 ide A-183 (EEWEVLCWTWETCER) suggested that a C-terminal extension into the FVIIa active site could yi
144 al of the 1291-1302-amino acid region of the C-terminal extension is critical for relieving the auto-
145 imeras we demonstrated that the ER alpha DBD C-terminal extension is required for directed DNA bendin
146 n1 is a critical centrosomal component whose C-terminal extension is required for proper recruitment
147 ation of serines 261 and 289, located in the C-terminal extension, is required for Gem-mediated cytos
150 first binding all phage containing A-183 and C-terminal extension libraries to immobilized and inacti
151 re domain harbors the nuclease activity, the C-terminal extension may be important for protein-protei
153 extension plus motif IV [betaB1(1-190)], or C-terminal extension + motif III + motif IV [betaB1(1-14
154 the cellular level we have characterized the C-terminal extension mutants and other mutants, addressi
156 Co-localization of the N terminus and the C-terminal extension near the hinge of the kinase domain
157 Here, we provide evidence that the unusual C-terminal extension negatively regulates phospholipid t
163 A and/or CssB subunits and a donor strand, a C-terminal extension of 16 amino acids that was derived
167 a striking example of how a splice-generated C-terminal extension of a sperm tail-associating protein
168 An A. aeolicus variant lacking the unique C-terminal extension of Aacpn10 displays the same kineti
169 co-crystal structure of LeuRS showed that a C-terminal extension of about 60 amino acids forms a dis
175 Both the C-terminal end of Bni5 and the C-terminal extension of Cdc11 make important contributio
177 s, an M-domain loop, and the cpSRP43 binding C-terminal extension of cpSRP54 are predominantly disord
179 apping by binding elements in the disordered C-terminal extension of Dcp2, alleviating autoinhibition
182 thermore, we show that residues 66-72 in the C-terminal extension of Escherichia coli Hfq are essenti
183 elocalized Plk1 from the centrosomes and the C-terminal extension of hCenexin1 was crucial to recruit
185 matin stabilization requires the lysine-rich C-terminal extension of HMO1 as truncation of the HMO1 C
186 by mutational and kinetic analysis that the C-terminal extension of human CysRS is used to selective
188 Our findings suggest that the Glu-rich long C-terminal extension of insect TnT functions as a myofil
192 Structures of pre-ribosomes lacking the C-terminal extension of Nog1 demonstrate that this exten
193 constrained through two disulfide bonds to a C-terminal extension of noncanonical secondary structure
194 drG subdomains followed by the movement of a C-terminal extension of one subdomain to cover the ligan
195 avior of the calmodulin (CaM) domain and the C-terminal extension of OsCaM61 in the absence and prese
199 onmental persistence, the interaction of the C-terminal extension of SpoIIID with DNA is a potential
200 ween the conserved and functionally critical C-terminal extension of TetM and the decoding center of
201 ween the conserved and functionally critical C-terminal extension of TetM with a unique splayed confo
202 tein, termed transframe (TF), comprised of a C-terminal extension of the 6K protein in the -1 open re
204 icity of CM15 expressed intracellularly as a C-terminal extension of the carrier protein ketosteroid
206 (KIND) of Spire directly interacts with the C-terminal extension of the formin homology domain 2 (FH
207 otein product (MCM9M) that eliminates a long C-terminal extension of the fully spliced product (MCM9L
209 nd spectroscopic analysis indicated that the C-terminal extension of the large subunit is essential f
212 rities between the PEAK1 SHED region and the C-terminal extension of the Parkinson's disease-associat
213 ain binding sites for MEKK2 and ERK5, with a C-terminal extension of the PB1 domain contributing to E
217 protein are responsible for re-directing the C-terminal extension of the second subdomain required fo
219 he complement proteins is a 150-residue-long C-terminal extension of their alpha-subunits that harbor
223 recently provided structural evidence that a C-terminal extension of TnI is anchored on actin at low
225 domain-swapping analysis identified that the C-terminal extension of VgrG1 specifically confers Tde1
226 ture consisting of a long glutamic acid-rich C-terminal extension of ~70 residues with unknown functi
228 rotetrameric coiled coils between the paired C-terminal extensions of Cdc3 and Cdc12 projecting ortho
232 acids mapping within this epitope, including C-terminal extensions of the CP, which would sterically
235 pared in which the N-terminal extension, the C-terminal extension or both extensions were deleted.
236 resent the structure of the human telomerase C-terminal extension (or thumb domain) determined by the
237 that both the catalytic site of CtBP and the C-terminal extension play important, if nonessential rol
238 252)], C-terminal extension [betaB1(1-234)], C-terminal extension plus motif IV [betaB1(1-190)], or C
239 bsequent deletions of the C-terminal domain (C-terminal extension plus motifs III and IV) while it re
240 a sheet to the last two alpha helices in the C-terminal extension, potentially providing a mechanism
241 ression of a mutant of TbECK1 that lacks the C-terminal extension produces a slow growth phenotype, a
242 d-coil tetramerization domain of P, and long C-terminal extensions projecting from these two helices,
243 in synthesized as an 80-amino acid ubiquitin C-terminal extension protein (CEP80), functions as a nov
244 l phosphatidylinositol binding domain, and a C-terminal extension related to the Gbetagamma binding d
246 the Spn4 proteins (Spn4.1) features a unique C-terminal extension, reminiscent of an endoplasmic reti
247 of the N-terminal domain (residues 1-63) or C-terminal extension (residues 140-173) affected the str
248 N-terminal domain (residues 1-63) deleted or C-terminal extension (residues 140-173) deleted alphaA m
249 ion (residues 45-74) and a partially ordered C-terminal extension (residues 285-362) that bridges the
252 he N terminus and a particular region of the C-terminal extension suppresses the intrinsic autophosph
254 NADP (+), and the characteristic AFVEK (258) C'-terminal extension that is typical of bacterial FPRs
255 obic inter-domain interactions and by the N2 C-terminal extension that complements a beta-sheet on N1
256 ably expresses mouse 5-HT(3A)Rs containing a C-terminal extension that confers high-affinity binding
257 to methionine aminopeptidases, coupled to a C-terminal extension that contains important motifs for
258 CopG consists of a thioredoxin domain with a C-terminal extension that contributes to metal binding.
260 a(2)-sigma(4) architecture and an additional C-terminal extension that encodes a SnoaL_2 domain, whic
262 complex, yet contains a eukaryotic-specific C-terminal extension that follows the tRNA anticodon-bin
263 ical RNA recognition motif with a disordered C-terminal extension that forms an alpha helix in the co
264 DbpA contain an approximately 80 amino acid C-terminal extension that has been proposed to specifica
265 ermit to drive conformational changes in the C-terminal extension that have been associated with sign
267 known GT-B structures, however, there is no C-terminal extension that interacts with the N-terminal
270 omposed of only a core domain, followed by a C-terminal extension that may serve as a ligand for bind
271 lysine residue and a tyrosine residue of the C-terminal extension that penetrates a partner subunit t
272 eption of EsxB, B. anthracis proteins harbor C-terminal extensions that are appended to canonical WXG
273 of this protein family often contain N- and C-terminal extensions that are responsible for additiona
274 ipain-B, and we show that it contains N- and C-terminal extensions that render a low amount of latenc
275 hate isomerase (TIM) barrel fold with N- and C-terminal extensions that tailor the structure of the e
276 y observed protein families often have N- or C-terminal extensions that were disordered or not presen
277 protein and is affected by a fungal-specific C-terminal extension, the conserved catalytic core, and
278 rystallin compared to deletion of either the C-terminal extension, the N-terminal domain, or the C-te
280 pens the HLA class I F' pocket, allowing the C-terminal extension to protrude through one end of the
282 ch differ by an approximately 500 amino acid C-terminal extension, unique among TGF-beta superfamily
285 a protein-peptide complex by designing N or C-terminal extensions which interact with the protein ou
286 COOH-terminal to the DNA-binding domain (the C-terminal extension), which is required for interaction
287 nal HerA-ATP synthase domain and a conserved C-terminal extension, which acts as a physical brace bet
288 nthetic organisms reveals the evolution of a C-terminal extension, which harbors the phosphorylation
290 This binding was not affected by cry1's C-terminal extension, which is important for signal tran
291 The precursor form of D1 (pD1) contains a C-terminal extension, which is removed by the protease C
293 potexvirus CP and phlebovirus NP is in their C-terminal extensions, which appear to determine the cha
295 the C-terminal lobe, and (iii) a 240 residue C-terminal extension with a modified cystine knot motif
297 contraction enzyme, CbiH(60), that harbors a C-terminal extension with sequence similarity to the nit
299 hanced its activity in agonizing TLR4, while C-terminal extension with the native FNIII 12-13-14 hepa
300 sequence is unchanged upon addition of a P10 C-terminal extension, yielding a critical nucleus of one