ライフサイエンスコーパス: C-type lectin

1 divalent cations, suggesting involvement of C-type lectins.

2 king mannose-dependent target cell entry via C-type lectins.

3 ized protein belonging to the superfamily of C-type lectins.

4 e newly-discovered heparin-binding proteins, C-type lectin 14a (CLEC14A), a member of the C-type lect

5 The human C-type lectin 18 (clec18) gene cluster, which contains t

6 with the glycoprotein VI collagen receptor, C-type lectin 2, the receptor for podoplanin, and Fc rec

7 tant, named Rosetteless, maps to a predicted C-type lectin, a class of signaling and adhesion genes r

8 ) adjacent to its ligand, activation-induced C-type lectin (AICL).

9 jacent to its ligand, ie, activation-induced C-type lectin (AICL).

10 stant ASFV strains and strongly suggest that C-type lectin and CD2v may experience substantial select

11 bined DC activation via Macrophage-inducible C-type lectin and TLR7/8 representing a novel approach t

12 ysfunction causes deficiencies in intestinal C-type lectins and antimicrobial peptides, which leads t

13 ace receptors (mannose receptor-1 (MRC1) and C-type lectins), and subsequent upregulation of cytokine

14 mune responses, with emphasis on the role of C-type lectins, and discuss how these receptors modulate

15 Our findings identify C-type lectins as mediators of membrane attack in the mu

16 ct coregulation with different cis-regulated C-type lectins, C3 was regulated in a coexpression netwo

17 Engagement of the C-type lectin CD161 on these cells inhibited TCR-depende

18 lining the medullary sinus (MS) expressed a C-type lectin CD209.

19 (-) LSCs are generally highly quiescent, the C-type lectin CD93 is expressed on a subset of actively

20 macrophage galactose-type lectin (MGL) is a C-type lectin characterized by a unique specificity for

21 The C-type lectin chondrolectin (chodl) represents one of th

22 erved that gut DCs express mRNA encoding for C-type lectin (CLEC) 7A, CLEC9A, CLEC12A, and CLEC4N.

23 ins, cathepsins, and the natural killer (NK)/C-type lectin (CLEC) complex [6-12].

24 We show that the group 14 C-type lectins CLEC14A, CD93 and CD248 directly bind to

25 C-type lectin CLEC16A is located next to CIITA, the mast

26 e have described how the recently discovered C-type lectin collectin-11 (CL-11, also known as CL-K1 a

27 The detection of an EhV86-encoded C-type lectin-containing protein confirmed that infectio

28 Mvarphi, whereas blockade of CLEC5A/MDL-1, a C-type lectin critical for dengue hemorrhagic fever and

29 The C-type lectins CTL4 and CTLMA2 cooperatively influence P

30 ed an enrichment for sequences homologous to C-type lectins (CTLs), an evolutionarily ancient family

31 suppresses RIG-I and Mda5 by activating the C-type lectin DC-SIGN and inducing signaling that preven

32 The C-type lectin DC-SIGNR (dendritic cell-specific ICAM-3-g

33 ound DCs and colocalized specifically to the C-type lectin DCIR.

34 that targeting nanoparticles to pDCs via the C-type lectins DEC-205, DC immunoreceptor, blood DC Ag-2

35 A monoclonal antibody against the C-type lectin DEC205 (alphaDEC205) is an effective vehic

36 The C-type lectin Dectin-1 binds to yeasts and signals eithe

37 Here, we report that C-type lectin dendritic cell (DC) immunoreceptor (DCIR),

38 We showed previously that the C-type lectins, dendritic cell-specific intercellular ad

39 ovel mucin-like glycoprotein that contains a C-type lectin domain (CTLD) and has orthologs in C. homi

40 active epitopes in the cysteine-rich (CysR), C-type lectin domain 1 (CTLD1), and C-type lectin domain

41 (CysR), C-type lectin domain 1 (CTLD1), and C-type lectin domain 7 (CTLD7) domains and confirmed the

42 ndent on a predicted long-loop region in the C-type lectin domain and is abrogated by mutation within

43 me 1 [ECE1], phosphofructokinase [PFKP], and C-type lectin domain containing 11A [CLEC11A]) normalize

44 The C-type lectin domain containing group 14 family members

45 ed macrophages based on surface marker CD301/C-type lectin domain family 10 member A expression.

46 d exposure; p=2.3x10-7) and was annotated to C-Type Lectin Domain Family 11, Member A (CLEC11A), whic

47 C-type lectin domain family 3 member A (CLEC3A) is a poo

48 Genetic variation in or near the C-type lectin domain family 4 member M (CLEC4M) has been

49 miR-125a reduced expression of C-type lectin domain family 5, member a (Clec5a), which

50 given soluble beta-glucans, which antagonize C-type lectin domain family 7 member A (CLEC7A or DECTIN

51 ll receptor delta chain) and Clec7a (encodes C-type lectin domain family 7 member a, also known as DE

52 expression of Cre recombinase driven by the C-type lectin domain family 9, member a (Clec9a) locus c

53 We found that the C-type lectin domain of CLEC14A binds one-to-one to hepa

54 tes, and hypertrophic chondrocytes secrete a C-type lectin domain protein, Clec11a, which promotes os

55 Here, we report that layilin, a C-type lectin domain-containing membrane glycoprotein, i

56 characterized a novel Cryptosporidium parvum C-type lectin domain-containing mucin-like glycoprotein,

57 ricin, fibronectin type II, first and second C-type lectin domains (CTLD).

58 e, we analyzed ASFV serotype-specific locus (C-type lectin (EP153R) and CD2v (EP402R)) in order to al

59 Collectin-11, a soluble C-type lectin expressed in renal tissue, has been implic

60 n the present study, we show that DC-SIGN, a C-type lectin expressed on DCs, binds directly to C1q, a

61 we have demonstrated that mice deficient in C-type lectin family 14 member A (CLEC14A) display enhan

62 angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain,

63 C-type lectin family 14, member A (CLEC14A), is a single

64 rofile was obtained by stimulating Dectin-1 (C-type lectin family member) on Rictor(-/-) DC.

65 Many members of the C-type lectin family of glycan-binding receptors have be

66 C-type lectin 14a (CLEC14A), a member of the C-type lectin family that modulates angiogenesis.

67 s X, a ligand specific for DC-SIGN among the C-type lectin family.

68 The array contains C-type lectins from cow, chosen as a model organism of a

69 disrupt the coding sequence of a S. rosetta C-type lectin gene, rosetteless, and thereby demonstrate

70 between microbes and the large complement of C-type lectins, here we developed a lectin array and sui

71 ors on antigen-presenting cells, such as the C-type lectin immune receptors mannose receptor (MR), ma

72 ope glycoprotein E2 is a novel ligand of pDC C-type lectin immunoreceptors (CLRs), blood DC antigen 2

73 ith the cognate CTLR keratinocyte-associated C-type lectin (KACL) selectively expressed by human kera

74 s NKC-encoded ligand keratinocyte-associated C-type lectin (KACL).

75 e infectious synapse or the interplay of the C-type lectins, Langerin on Langerhans cells (LCs), and

76 e receptors include members of the NKRP1 and C-type lectin-like 2 (CLEC2) gene families, which consti

77 re was a preferential expansion of licensed, C-type lectin-like activating receptor Ly49H+ NK cells w

78 immunoglobulin-like receptors (KIRs) and the C-type lectin-like CD94:NKG2 receptors.

79 reas KACL forms a homodimer resembling other C-type lectin-like dimers, NKp65 is monomeric.

80 , several amino acid residues located in the C-type lectin-like domain (CTLD) and the sperm-coating p

81 It possesses a C-type lectin-like domain (CTLD) followed by a poorly ch

82 We also show that the second C-type lectin-like domain (CTLD2) is critical for the up

83 (CysR), fibronectin-like type II (FnII), and C-type lectin-like domain 1 (CTLD1) domains of PLA2R onl

84 ecently we solved a crystal structure of the C-type lectin-like domain of a homologous protein, NKR-P

85 and interpret the solution structure of the C-type lectin-like domain of NKR-P1C using chemical cros

86 d raises the possibility that a protein with C-type lectin-like domains regulated development in the

87 ructure comprising two intercalated rings of C-type lectin-like domains, where the N-terminal cystein

88 ar localization of AICL is determined by its C-type lectin-like ectodomain.

89 s (Nkrp1, NKRP1A, NKp80, NKp65) instead bind C-type lectin-like ligands to which they are genetically

90 ort the first characterization of the orphan C-type lectin-like molecule Clr-a encoded by the Clec2e

91 Human C-type lectin-like molecule-1 (CLL1) is a recently ident

92 onredundant function of these highly related C-type lectin-like molecules in the context of intestina

93 also involves NK gene complex (NKC)-encoded C-type lectin-like molecules such as NKG2D and Nkrp1 rec

94 Interactions between C-type lectin-like NK cell receptors and their protein l

95 AM)-coupled receptors glycoprotein (GP)VI or C-type lectin-like receptor (CLEC)-2 is associated with

96 NKp65 is an activating human C-type lectin-like receptor (CTLR) triggering cellular c

97 C-type lectin-like receptor 2 (CLEC-2) is a platelet rec

98 C-type lectin-like receptor 2 (CLEC-2) is an essential p

99 Platelet C-type lectin-like receptor 2 (CLEC-2) is known to maint

100 ng mouse development, binding of Pdpn to the C-type lectin-like receptor 2 (CLEC-2) on platelets is c

101 ong them are a platelet activation receptor, C-type lectin-like receptor 2 (CLEC-2), and its endogeno

102 eptor glycoprotein (GP)VI-FcRgamma chain and C-type lectin-like receptor 2 (CLEC-2)-mediated platelet

103 nd proplatelet formation by interaction with C-type lectin-like receptor 2 (CLEC-2).

104 llagen receptor glycoprotein (GP) VI and the C-type lectin-like receptor 2 (CLEC-2).

105 nctions as an activating ligand for platelet C-type lectin-like receptor 2 (CLEC-2, also known as CLE

106 ycoprotein VI (GPVI) and podoplanin receptor C-type lectin-like receptor 2 (CLEC2) are receptors impl

107 deficient for the platelet-specific receptor C-type lectin-like receptor 2 (CLEC2) as blood backfills

108 Glycoprotein VI and C-type lectin-like receptor 2 are essential platelet act

109 ost completely inhibited glycoprotein VI and C-type lectin-like receptor 2 signaling.

110 ompound specifically inhibited collagen- and C-type lectin-like receptor 2-induced human platelet agg

111 elective and essential role in collagen- and C-type lectin-like receptor 2-mediated platelet activati

112 he collagen receptor glycoprotein VI and the C-type lectin-like receptor 2.

113 CD141(+) DC in humanized mice express C-type lectin-like receptor 9A, XCR1, CADM1, and TLR3 bu

114 ng injection of Abs against human DEC-205 or C-type lectin-like receptor 9A.

115 NKp80 is a C-type lectin-like receptor broadly expressed on human n

116 The C-type lectin-like receptor CLEC-2 mediates platelet act

117 The activation of platelet receptor C-type lectin-like receptor II-type (CLEC-2) could parti

118 Among these is the C-type lectin-like receptor NKp80 which is encoded in th

119 The mouse C-type lectin-like receptor Nkrp1g was previously shown

120 rative integration of Toll-like receptor and C-type lectin-like receptor signaling mechanisms culmina

121 Ly49Q, a C-type lectin-like receptor specific for MHC-I, possesse

122 ecently discovered platelet receptor CLEC-2 (C-type lectin-like receptor) perpetuates and worsens liv

123 rs thrombosis within vessels via ligation of C-type lectin-like receptor-2 (CLEC-2) on platelets by p

124 he following receptors: glycoprotein (GP)VI, C-type lectin-like receptor-2 (CLEC-2)>GPIb>alpha6beta1,

125 Rhodocytin, an agonist of the C-type lectin-like receptor-2 (CLEC-2), elicits powerful

126 killer gene complex-encoded immunomodulatory C-type lectin-like receptors include members of the NKRP

127 ler (NK) gene complex (NKC) encodes numerous C-type lectin-like receptors that govern the activity of

128 us pathogen recognition receptors, including C-type lectin-like receptors, TLRs, and nucleotide oligo

129 itutive or platelet-specific deletion of the C-type-lectin-like receptor (CLEC-2) exhibit hemorrhagin

130 he podoplanin and collagen/fibrin receptors, C-type-lectin-like-2 (CLEC-2) and glycoprotein VI (GPVI)

131 The C-type lectin macrophage galactose-type lectin (MGL) exe

132 s were used that have high expression of the C-type lectin mannose receptor (MR; CD206).

133 Identification of the C-type lectin Mincle as one of the receptors underlying

134 We previously identified the C-type lectin Mincle as receptor for these glycolipids t

135 The role of macrophage-inducible C-type lectin Mincle in lung innate immunity against myc

136 reover, M. bovis BCG-induced upregulation of C-type lectin Mincle on professional phagocytes critical

137 C-type lectin receptors macrophage-inducible C-type lectin (Mincle) and Mcl to activate macrophages.

138 necrotic osteocytes via macrophage-inducible C-type lectin (Mincle), which induced their differentiat

139 her, our results reveal a pathway by which a C-type lectin modulates the equilibrium between infectio

140 rfactant Protein D (SP-D) is an oligomerized C-type lectin molecule with immunomodulatory properties

141 , including genome-wide significance for the C-type lectin molecules CLEC4F-CD207 at 2p13.3 and CLEC4

142 at the gut microbiome in mosquitoes utilizes C-type lectins (mosGCTLs) to evade the bactericidal capa

143 ycystic kidney disease (PKD) domain, and the C-type lectin motif, while the larger one is the C-termi

144 pothesized that langerin, the distinguishing C-type lectin of Langerhans cells, would recognize the h

145 e we investigated whether sCD93, a group XIV c-type lectin of the endosialin family, plays a role in

146 C-type lectins of the RegIII family are bactericidal pro

147 Langerin, a C-type lectin on Langerhans cells, mediates carbohydrate

148 Dectin-2, a C-type lectin on macrophages and other cells of the inna

149 -based activation motifs (hemITAMs) found in C-type lectin pattern recognition receptors.

150 Selectins, a family of C-type lectins, play a key role in inflammatory diseases

151 Langerin is a C-type lectin present on Langerhans cells that mediates

152 The discovery that proteins called c-type lectins promote bone growth could lead to new tre

153 Lastly, we found Dectin-1, a c-type lectin PRR to be reduced at the protein level in

154 id not occur in mice lacking alpha-granules, C type lectin receptor-2 (CLEC-2), or protease activated

155 we show that a toll-like receptor (TLR) and C-type lectin receptor (CLR) agonist pairing of monophos

156 ed N-glycans that support recognition by the C-type lectin receptor (CLR) DC-specific intercellular a

157 DC-asialoglycoprotein receptor (DC-ASGPR), a C-type lectin receptor (CLR) expressed on human DCs, res

158 Whether the PRRs of the C-type lectin receptor (CLR) family including Dectin-2 m

159 Members of the C-type lectin receptor (CLR) family stand out among the

160 RS-CoV replication significantly upregulated C-type lectin receptor (CLR) macrophage-inducible Ca2+-d

161 acteria, trehalose dimycolate, activates the C-type lectin receptor (CLR) Mincle.

162 Fungal infection stimulates the canonical C-type lectin receptor (CLR) signaling pathway via activ

163 The interaction of C-type lectin receptor 2 (CLEC-2) on platelets with Podo

164 ne-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through

165 TLRA/C-type lectin receptor agonist combinations were screene

166 uvant consisting of a Toll-like receptor and C-type lectin receptor agonist pairing that significantl

167 ited that distinct combinations of TLRAs and C-type lectin receptor agonists may enhance Th1 response

168 CD302 as the simplest, single domain, type I C-type lectin receptor and showed it was expressed mainl

169 The C-type lectin receptor blood dendritic cell Ag 2 (BDCA2)

170 display an 18-fold higher expression of the C-type lectin receptor CD209a, a murine homolog of human

171 Here, we show that the C-type lectin receptor CD69 controls tTreg cell developm

172 The C-type lectin receptor CLEC-2 signals through a pathway

173 Among the genes most upregulated in pDC were C-type lectin receptor CLEC4E, IL-1Rs (IL-1R1 and -2), p

174 Here, we have identified the C-type lectin receptor CLECSF8 (CLEC4D, MCL) as a key mo

175 dependent antibodies 2G12 and PGT123, or the C-type lectin receptor DC-SIGN.

176 uman dendritic cells (DCs) via targeting the C-type lectin receptor DC-specific intercellular adhesio

177 Here, we found that the FcRgamma-coupled C-type lectin receptor DCAR (dendritic cell immunoactiva

178 The myeloid C-type lectin receptor Dectin-2 directs the generation o

179 a-mannan (Mn), an Mn (sugar) polymer, by the C-type lectin receptor Dectin-2 on host macrophages lead

180 t of opsonization but appears to require the C-type lectin receptor Dectin-3, a receptor not previous

181 hesion molecule-3-grabbing nonintegrin) is a C-type lectin receptor expressed on macrophages and dend

182 DDCs; furthermore, common unique patterns of C-type lectin receptor expression were identified betwee

183 n monocytes, macrophages, and DC; determined C-type lectin receptor expression; and tested the contri

184 nt have been the parallel discoveries in the C-type lectin receptor family and the Th effector arms o

185 es are known to interact with members of the C-type lectin receptor family of pattern recognition pro

186 Many members of the C-type lectin receptor family serve as pattern recogniti

187 cription profile of all KIR family genes and C-type lectin receptor genes using RNA sequencing on NKT

188 rbohydrate recognition domain of Langerin, a C-type lectin receptor involved in the host defense agai

189 of the human and murine forms of the myeloid C-type lectin receptor langerin for simple and complex l

190 Langerhans cells (eLCs) uniquely express the C-type lectin receptor langerin in addition to the HIV e

191 Their exclusive expression of the C-type lectin receptor Langerin makes them prominent can

192 d mucosal Langerhans cells (LCs) express the C-type lectin receptor langerin that functions as a patt

193 that neutrophils elicited in the presence of C-type lectin receptor ligands have an increased ability

194 cture Lewis(X) (Le(X)) re-directs OVA to the C-type lectin receptor MGL1.

195 tor trehalose-6,6-dimycolate (TDM) binds the C-type lectin receptor MINCLE and induces inflammatory g

196 The Syk-coupled C-type lectin receptor Mincle detected mucosal-resident

197 ined a previously uninvestigated role of the C-type lectin receptor Mincle in pneumonic sepsis caused

198 id trehalose dimycolate (cord factor) by the C-type lectin receptor mincle partially explains this CA

199 selectively recognized by Mincle (Clec4e), a C-type lectin receptor of the innate immune system that

200 Mincle is a C-type lectin receptor of the innate immune system with

201 The C-type lectin receptor pathway activates both MAPK and N

202 We sought to analyze C-type lectin receptor pathways as an alternative or a c

203 is report, we demonstrate that expression of C-type lectin receptor scavenger receptor-AI (SR-AI) is

204 further show that recruited IDCs express the C-type lectin receptor SIGN-R1, which mediates direct re

205 ation, IL-17 signaling, Chemokine signaling, C-type lectin receptor signaling and Toll-like receptor

206 results illustrate the complexity of myeloid C-type lectin receptor signaling, and how an activating

207 DNGR-1 is a C-type lectin receptor that binds F-actin exposed by dyi

208 Dectin-1 (Clec7a) is a paradigmatic C-type lectin receptor that binds Syk through a hemITAM

209 ec12A is a myeloid cell-expressed inhibitory C-type lectin receptor that can sense cell death under s

210 Mincle is a C-type lectin receptor that is critical in the immune re

211 ection occurs upon engagement of Dectin-1, a C-type lectin receptor that signals via spleen tyrosine

212 Clec9a (C-type lectin receptor) or DNGR-1 (dendritic cell NK lec

213 s recognized by Mincle (macrophage inducible C-type lectin receptor), and its adjuvanticity depends o

214 aration during development by activating the C-type lectin receptor, CLEC-2, on platelets.

215 Here, we identified functions of one C-type lectin receptor, CLEC12A, in facilitating DC bind

216 We investigated the role of the C-type lectin receptor, CLEC5A, in macrophage activation

217 study, we demonstrated that activation of a C-type lectin receptor, dectin-1, in MDSC differentially

218 This notably depends on the C-type lectin receptor, langerin or DC-SIGN, involved in

219 Dual activation of newborn DCs via the C-type lectin receptor, macrophage-inducible C-type lect

220 we examined the mechanism by which Mincle, a C-type lectin receptor, regulates NET formation.

221 nificantly higher induction of CD23, a novel C-type lectin receptor, through NFATc1-mediated regulati

222 Although C-type lectin receptor- and Toll-like receptor-induced s

223 ith bone marrow-derived dendritic cells from C-type lectin receptor-deficient mice revealed that the

224 t protein and mRNA levels, thereby affecting C-type lectin receptor-induced modulation of IDO activit

225 The C-type lectin receptor-Syk (spleen tyrosine kinase) adap

226 but not spores and depends upon Dectin-1, a C-type lectin receptor.

227 beta) that are associated with activation of C-type lectin receptors (CLR) Dectin-1- and Dectin-2-med

228 ted in significant mRNA upregulation of both C-type lectin receptors (CLR) Mincle and MCL in Msg prot

229 The C-type lectin receptors (CLR) MINCLE, MCL, and DECTIN-2

230 C-type lectin receptors (CLRs) are essential in shaping

231 Several spleen tyrosine kinase-coupled C-type lectin receptors (CLRs) have emerged as important

232 However, the role of TRAF6 and TAK1 in C-type lectin receptors (CLRs) in response to fungal inf

233 Herein we demonstrate that 2 C-type lectin receptors (CLRs) Mcl and Mincle play an im

234 C-type lectin receptors (CLRs) play key roles in antifun

235 C-type lectin receptors (CLRs) represent a family of pat

236 avoid degradation, as virus engagement with C-type lectin receptors (CLRs), such as DC-SIGN (DC-spec

237 C-type lectin receptors (CLRs), the carbohydrate-recogni

238 attern recognition receptors (PRRs) known as C-type lectin receptors (CLRs).

239 ion by pattern recognition receptors such as C-type lectin receptors (CLRs).

240 y various TLRs (TLR2, TLR3, TLR4, and TLR7), C-type lectin receptors (Dectin-1, Dectin-2, and Mincle)

241 terial toll-like receptors (TLRs) and fungal C-type lectin receptors (e.g., dectin-1).

242 on receptors, including Toll-like receptors, C-type lectin receptors and NOD-like receptors.

243 targeting and activating dendritic cells via C-type lectin receptors and reduce side effects.

244 (+) DCs exhibited a restricted repertoire of C-type lectin receptors and relied on CD4 for uptake of

245 w these patterns impact their recognition by C-type lectin receptors and the immunomodulatory effect

246 cterized member of the "Dectin-2 cluster" of C-type lectin receptors and was originally thought to be

247 In this context, endocytic C-type lectin receptors are attractive targeting molecul

248 CLEC-2 is a member of new family of C-type lectin receptors characterized by a cytosolic YXX

249 Conversely, signaling via other C-type lectin receptors did not alter disease course.

250 n of DNGR-1 is replaced by that of unrelated C-type lectin receptors fail to promote cross-presentati

251 eptor (PAR)-2, Toll-like receptor (TLR), and C-type lectin receptors have been suggested to be import

252 led receptors, receptor tyrosine kinase, and C-type lectin receptors in the context of recent progres

253 d activation of both Toll-like receptors and C-type lectin receptors is required for IRF1-mediated IR

254 g Trehalose-6,6-dibehenate (TDB) bind to the C-type lectin receptors macrophage-inducible C-type lect

255 In rodents, the C-type lectin receptors Mincle and Mcl bind TDB/TDM and

256 We have previously shown that different C-type lectin receptors on DCs play a major role in alle

257 that stochastic activation of toll-like and c-type lectin receptors on macrophages causes neuroprote

258 C-type lectin receptors play important roles in immune c

259 C-type lectin receptors sense a diversity of endogenous

260 Therein, the endocytic C-type lectin receptors serve as pattern recognition rec

261 ens to specific compartments is regulated by C-type lectin receptors that recognize glycan structures

262 Surprisingly, activity at the C-type lectin receptors was particularly powerful, with

263 In a targeted screen of C-type lectin receptors, a Clec2d reporter responded to

264 t of anti-fungal innate immune signaling via C-type lectin receptors, and several immune-related diso

265 pendent of FcgammaRII, type II Fc receptors, C-type lectin receptors, and sialic acid-binding immunog

266 ginase activity and parasite growth involved C-type lectin receptors, because mannose injection decre

267 by interactions with CD4 and mannose-binding C-type lectin receptors, but not with the chemokine rece

268 ation is mediated through the recognition of C-type lectin receptors, mainly elicited by structurally

269 ora and damaged epithelium via expression of C-type lectin receptors, many of which signal through th

270 effects on the expression levels of two key C-type lectin receptors, namely the mannose receptor and

271 se in gene expression, particularly of TLRs, C-type lectin receptors, several complement components,

272 s related to DC surface receptors (including C-type lectin receptors, TLRs, and galectins).

273 ion, skin DCs bound and internalized Env via C-type lectin receptors, whereas blood DC subsets, inclu

274 se to C. albicans infection via signals from C-type lectin receptors, which signal through the adapto

275 specific expression pattern was observed for C-type lectin receptors.

276 latory molecules but prominent expression of C-type lectin receptors.

277 f mannan and, thus, likely to be mediated by C-type lectin receptors.

278 The innate pattern recognition C-type-lectin receptors (CLRs), including mannose recept

279 rresponded to an altered ileal expression of C-type lectins Reg3gamma and Reg3beta, and of interleuki

280 ithelial antimicrobial response, such as the C-type lectins Reg3gamma and Reg3beta.

281 s that include induction of the bactericidal C-type lectin RegIIIgamma.

282 l function upon interaction with its cognate C-type lectin-related ligand, Clr-b.

283 a2beta1 integrin-blocking members within the C-type lectin-related protein family is less strict than

284 duced SIRS-like conditions), we employed the C-type lectin-related protein rhodocetin-alphabeta (RCal

285 receptor protein-1B (NKR-P1B) and its ligand C-type lectin-related-b (Clr-b).

286 Antibodies to DC-SIGN, a c-type lectin selectively expressed by macrophages but n

287 protein in myeloid cells that is involved in C-type lectin signaling and antifungal immunity.

288 For example, cross-talk of TLR and C-type lectin signaling effectively shapes distinct gene

289 NCK2187 and its purified SlpA bind to the C-type lectin SIGNR3 to exert regulatory signals that re

290 Langerin, a trimeric C-type lectin specifically expressed in Langerhans cells

291 macrophage galactose-type lectin (MGL) is a C-type lectin that binds to glycoproteins expressing ter

292 Reg3gamma is an antimicrobial C-type lectin that is induced by STAT3 signaling in resp

293 hese results indicate that CpClec is a novel C-type lectin that mediates C. parvum attachment and inf

294 MBL is a C-type lectin that recognizes oligosaccharides on pathog

295 C-type lectins that contain collagen-like domains are kn

296 ive peptidases, 9 peptidase inhibitors and 7 C-type lectins that may function in interactions with in

297 x glycans that enables it to bind to certain C-type lectins, thereby enhancing its attachment to targ

298 mannosylated surface structures and exploits C-type lectins to gain cell access.

299 C-type lectin receptor, macrophage-inducible C-type lectin (trehalose-6,6-dibehenate), and TLR7/8 (R8

300 eration of selected bacteria by culture, and C-type lectins were assessed in ileal tissues by reverse