ライフサイエンスコーパス: C2H2 zinc finger

1 ino acid sequence identified a novel type of C2H2 zinc finger.

2 st three protein isoforms that contain 12-18 C2H2 zinc fingers.

3 , that encode proteins with highly conserved C2H2 zinc fingers.

4 a DNA binding domain with three consecutive C2H2 zinc fingers.

5 itated by repeats of sequence motifs such as C2H2 zinc fingers.

6 eceptors and proteins with three consecutive C2H2 zinc fingers.

7 dsRNA binding domain consisting of multiple C2H2 zinc fingers.

8 odes several functional domains, including a C2H2 zinc finger, a leucine zipper, and a winged-helix/f

9 KS1 contains 10 C2H2 zinc fingers, a KRAB-A/B motif, and an ID sequence

10 was localized to an evolutionarily conserved C2H2 zinc finger and leucine zipper motif.

11 ferase bi-domain module with a RET1-specific C2H2 zinc finger and RNA recognition (RRM) domains.

12 des a large protein containing 12 widespread C2H2 zinc fingers and 3 motifs containing periodic proli

13 Characteristic motifs of C2H2 zinc fingers and leucine heptad repeats are present

14 to a reduction of PIWI-interacting RNAs and C2H2 zinc-finger and Kruppel-associated box (KRAB)-domai

15 aa, each having a DNA-binding domain (eight C2H2 zinc fingers) and a proline-rich transcription acti

16 C2H2 zinc fingers are found in several key transcription

17 C2H2 zinc finger bearing proteins are a large superfamil

18 The C2H2 zinc finger (C2H2-ZF) is the most numerous protein

19 These data show that single C2H2 zinc fingers can bind RNA specifically and suggest

20 The Kruppel-like factor 10 (KLF10) is a C2H2 zinc-finger containing transcription factor.

21 The C2H2 zinc-finger-containing transcription factors encode

22 C2H2 zinc fingers define the largest transcription facto

23 een the CRL4(CRBN) E3 ubiquitin ligase and a C2H2 zinc finger degron motif, resulting in degradation

24 een the CRL4(CRBN) E3 ubiquitin ligase and a C2H2 zinc finger degron motif.

25 gle DNA binding homeodomain but lacks both a C2H2 zinc finger DNA binding domain and an apparent Dig1

26 transcription factors that share a common 3 C2H2 zinc finger DNA binding domain and have broad activ

27 is the founding member of a small family of C2H2 zinc-finger DNA-binding proteins that carry out cri

28 t integrates crystallographic information of C2H2 zinc finger-DNA complexes with binding data from 11

29 We show that the conserved N-terminal C2H2 zinc finger domain is essential for direct DNA bind

30 ar domain structure, including an N-terminal C2H2 zinc finger domain, a central putative core transpo

31 ee different protein isoforms that contain a C2H2 zinc-finger domain.

32 C4 is packed against N-terminal GRF-type and C2H2 zinc finger domains and a C-terminal CCHC domain, c

33 Half of all human transcription factors use C2H2 zinc finger domains to specify site-specific DNA bi

34 the C-terminal 174 amino acids contains five C2H2 zinc finger domains, and the N terminus (residues 1

35 nsertion sites in two additional Cys6Zn2 and C2H2 zinc finger domains, providing a starting point for

36 and CCCTC-binding factor (CTCF), with eleven C2H2 zinc finger domains.

37 alternative splicing to one of four pairs of C2H2 zinc-finger domains (Z1, Z2, Z3, and Z4).

38 re, that combines two functionally essential C2H2 zinc-finger domains, which are probably involved in

39 We demonstrate that mutations of the C2H2 zinc fingers encoded by the him-8 (high incidence o

40 Located on chromosome 5A, B1 is a C2H2 zinc finger encoding gene with ethylene-responsive

41 rotein 1) is one member of a small family of C2H2 zinc finger-encoding sequences previously character

42 We now find that the hunchback/Ikaros-like C2H2 zinc-finger factor ztf-16 is also required.

43 motifs for the nuclear hormone receptor and C2H2 zinc finger families and reveal unexpected diversit

44 ers indicates that ZBP-89 is a member of the C2H2 zinc finger family subclass typified by the Drosoph

45 C2H2 zinc-finger family members are key targets of DE mi

46 Here we provide evidence for a C2H2 zinc finger gene family with similarity to Ikaros a

47 A novel C2H2 zinc finger gene, ZNF277, has been localized to hum

48 ription factors and is found in more than 60 C2H2 zinc finger genes in the human genome, including th

49 ntrotus purpuratus genome, we identified the C2H2 zinc finger genes indicated in the sequence, and ex

50 We have isolated Kruppel-type (C2H2) zinc-finger genes, ZIM3 (zinc-finger gene 3 from i

51 Examples explored in this study include C2H2 zinc finger, homeodomain and bHLH DNA-binding motif

52 tobacco has a higher proportion of ERF/AP2, C2H2 zinc finger, homeodomain, GRF, TCP, zinc finger hom

53 , a class of zinc finger proteins containing C2H2 zinc fingers in tandem arrays of two or three is pr

54 The C2H2 zinc finger is one of the most abundant protein dom

55 The C2H2 zinc finger is the most commonly utilized framework

56 The C2H2 zinc finger is the most prevalent protein motif in

57 roteins that contain two atypical Cys2/His2 (C2H2) zinc finger-like domains that are evolutionarily w

58 ferentiation via an evolutionarily conserved C2H2 zinc finger motif.

59 milar DNA binding structure of four and five C2H2 zinc finger motifs (ZF), respectively.

60 ists of a basic N-terminal region with seven C2H2 zinc finger motifs and an acidic C-terminal region

61 Sequence analysis reveals eight C2H2 zinc finger motifs at the C-terminus of ZNF210 and

62 Members of one group include C2H2 zinc finger motifs.

63 ption factors characterized by seven to nine C2H2 zinc finger motifs.

64 on factor that contains a BTB/POZ domain and C2H2 zinc finger motifs.

65 The predicted Tef protein contains three C2H2 zinc-finger motifs, one at the amino terminus and t

66 brid screen, encoded a protein containing 29 C2H2 zinc fingers of the TFIIIA type.

67 In animal systems the C2H2 zinc finger protein (ZFP) gene family is the larges

68 e showed that two genes encoding Arabidopsis C2H2 ZINC FINGER PROTEIN (ZFP) transcription factors, ZP

69 eotide primer, for the facile isolation of a C2H2 zinc finger protein cDNA (Pszf1) from pea petals.

70 The die-1 gene encodes a C2H2 zinc finger protein containing four fingers, which

71 An ortholog of one of these, the C2H2 zinc finger protein DEFECTIVELY ORGANIZED TRIBUTARI

72 C2H2 zinc finger protein genes encode nucleic acid-bindi

73 BEL1-like homeodomain protein PINNA1 and the C2H2 zinc finger protein PALMATE-LIKE PENTAFOLIATA1 (PAL

74 nine aminopeptidases (MetAPs), and Rei1 is a C2H2 zinc finger protein whose function in ribosome biog

75 sible for awn inhibition in wheat, encodes a C2H2 zinc finger protein with EAR motifs which putativel

76 Here, we report that ZFP3, a nuclear C2H2 zinc finger protein, acts as a negative regulator o

77 Roaz, a rat C2H2 zinc finger protein, plays a role in the regulation

78 his study, LoZAT12, a Lilium oriental hybrid C2H2 zinc finger protein, was found to be a key regulato

79 e identification of a SCAN domain-containing C2H2 zinc finger protein, ZNF24, that represses the tran

80 Here we discovered that a C2H2 zinc finger protein, ZNF827, is strongly induced du

81 scription factor-binding motif for ZNF263, a C2H2 zinc finger protein.

82 e contains binding sites for a non-canonical C2H2 zinc finger protein.

83 ption of 5S rRNA genes and is the archetypal C2H2 zinc finger protein.

84 The C2H2 zinc-finger protein Pita binds to several BX-C boun

85 tlp-1 encodes a C2H2 zinc-finger protein that is a member of the Sp fami

86 him-8 encodes a C2H2 zinc-finger protein that is expressed during meiosi

87 We show that lin-48 encodes a C2H2 zinc-finger protein that is similar to the product

88 Mutants of pita, which encodes a C2H2 zinc-finger protein, are homozygous lethal and show

89 he Drosophila Doublefault (Dbf) protein as a C2H2 zinc-finger protein, primarily expressed in testes,

90 We cloned ehn-3, and found that it encodes a C2H2 zinc-finger protein.

91 ZFP24, a Cys2-His2 (C2H2) zinc finger protein, is essential for oligodendroc

92 ists of 11 exons and encodes a Kruppel-type (C2H2) zinc-finger protein with a conserved Kruppel-assoc

93 er gene 1), encoding a typical Kruppel-type (C2H2) zinc-finger protein, located within 30 kb of a kno

94 forty leaflets, we show that MPL1 encoding a C2H2-zinc finger protein sculpts a morphogenetic gradien

95 , KRIP-1 interacts with the KRAB-A region of C2H2 zinc finger proteins and may mediate or modulate KR

96 on a family of ubiquitously expressed human C2H2 zinc finger proteins comprised of ZFX, ZFY and ZNF7

97 C2H2 zinc finger proteins that do not bind arsenic were

98 criptomic profiling of three mutants lacking C2H2 zinc finger proteins, ypr013cDelta,ypr015cDelta and

99 ther, largely due to extensive divergence in C2H2 zinc finger proteins.

100 expansion and diversification of repressive C2H2 zinc finger proteins.

101 rs of the large, but under-studied family of C2H2 zinc finger proteins.

102 found near the N-terminus of a subfamily of C2H2 zinc finger proteins.

103 tal biological processes: DNA recognition by C2H2 zinc-finger proteins and homology-directed repair o

104 C2H2 zinc-finger proteins play important roles in plant

105 Here, we show that a family of four related C2H2 zinc-finger proteins plays a central role in these

106 ted Rox7, is shown here to be Mot3, a global C2H2 zinc finger regulator.

107 LA (SAP) genes and novel subfamilies of BES, C2H2 zinc finger, SAP, and NAC genes.

108 c-binding motifs in the form of two separate C2H2 zinc finger sequences.

109 xidase protein, AtSWP1, and a plant-specific C2H2 zinc finger-SET domain protein, AtCZS, interact wit

110 large and highly variable numbers of tandem C2H2 zinc finger (tandem ZF) transcription factor protei

111 Among a large pool of C2H2-zinc finger targets, PBK is essential for evicting

112 that the ASE motif is a binding site for the C2H2 zinc finger TF CHE-1, which is essential for the co

113 yeast fbp1 gene, binding of Rst2 (a critical C2H2 zinc-finger TF) is mediated by a local loop structu

114 a physical interaction between UNC-3 and the C2H2 zinc finger transcription factor PAG-3, the mammali

115 Here, we describe lsy-2, a novel C2H2 zinc finger transcription factor that is required f

116 riments indicated that the activation of the C2H2 zinc finger transcription factor, AT5G06070/RABBIT

117 The activation of a C2H2 zinc finger transcription factor, AT5G27880/HVA, is

118 thought to occur only in eukaryotes, a novel C2H2 zinc finger transcription factor, Ros, which regula

119 e observed upon postembryonic removal of two C2H2 zinc finger transcription factors, die-1 and che-1,

120 nding profiles for a benchmark set of eleven C2H2 zinc finger transcription factors, five of known an

121 logenetically conserved binding site for the C2H2 zinc-finger transcription factor CHE-1, a previousl

122 logos for the DNA-binding preferences of the C2H2 zinc-finger transcription factor family members.

123 OVOL2 encodes ovo-like zinc finger 2, a C2H2 zinc-finger transcription factor that regulates mes

124 JAGGED (JAG), a gene that encodes a putative C2H2 zinc-finger transcription factor, as a key regulato

125 development, POPOVICH (POP), which encodes a C2H2 zinc-finger transcription factor.

126 BCL11 proteins are related C2H2 zinc-finger transcription factors that act as trans

127 a nematode-specific, fast-evolving family of C2H2 zinc-finger transcription factors, lsy-27, is mutat

128 RABBIT EARS (RBE) encodes a C2H2 zinc finger transcriptional repressor and is requir

129 Here, we show that the C2H2 zinc finger transcriptional repressor encoded by RA

130 ntaining only two predicted genes, including C2H2 zinc finger transcriptional repressor TraesCS5A02G5

131 The SUPERMAN (SUP) gene encodes a C2H2 zinc-finger transcriptional repressor that regulate

132 ction of two conserved DNA-binding motifs, a C2H2 zinc finger (ZF) and a Myb motif, located within th

133 In contrast, C2H2 zinc finger (ZF) proteins recognize CpG and CpA, wh

134 are already known for HbF control; (2) seven C2H2 zinc finger (ZF) proteins, including some (ZBTB7A a

135 hrough sequence-specific DNA binding via its C2H2 zinc finger (ZF) tandem array, which is highly poly