ライフサイエンスコーパス: CD4-positive

1 lation stimulated by these Dsg3 peptides was CD4 positive.

2 One-third of infiltrating T cells were CD4 positive.

3 ase-line percentage of lymphocytes that were CD4-positive, a higher weight for age, a higher height f

4 ry infiltrate, cluster of differentiation 4 (CD4)-positive and CD8(+) T-lymphocyte levels, and viral

5 activation of cluster of differentiation 4 (CD4)-positive and cluster of differentiation 8 (CD8)-pos

6 tudying the entry of three SIV isolates into CD4-positive and CD4-negative cells expressing different

7 Both CD4-positive and CD4-negative peripheral blood dendritic

8 ytes, Kupffer cells, hepatic stellate cells, CD4-positive and CD8-positive lymphocytes, and cholangio

9 culum spp levels were associated with higher CD4-positive and CD8-positive TIL counts.

10 only one, MF275, inhibited the infection of CD4-positive CCR5-positive cells by some HIV-1 strains.

11 e, CCR5-positive cells, but the infection of CD4-positive, CCR5-positive cells was inhibited.

12 Virus bound to both CD4-positive (CD4(+)) and CD4-negative (CD4(-)) cells, i

13 V challenge, further eliciting robust memory CD4-positive (CD4(+)) and CD8(+) T-cell and ZIKV-specifi

14 tional ability to stimulate antigen-specific CD4-positive (CD4(+)) and CD8(+) T-cell responses.

15 -gp41 heterodimers mediates virus entry into CD4-positive (CD4(+)) cells.

16 CD4-positive (CD4(+)) T cells are the main contributors

17 phoid tissues and of IL-4-producing Th2-type CD4-positive (CD4(+)) T cells than did controls.

18 OVA-specific Ab and CD4-positive (CD4(+)) T-cell responses were determined.

19 CD4-positive (CD4+) T cells isolated from mucosal compar

20 Our laboratory discovered that CD4-positive (CD4+) T cells of the immune system convey

21 s mucosal adjuvant requires IL-4 and induces CD4-positive (CD4+) Th2-type responses, while nLT up-reg

22 of PSCA-vaccinated mice were infiltrated by CD4-positive, CD8-positive, CD11b-positive, and CD11c-po

23 infection of a CD4-positive precursor cell (CD4 positive/CD8 positive) with subsequent differentiati

24 B) was defined similarly, using the dates of CD4-positive cell counts or HIV-1 RNA measurements.

25 e of T-tropic HIV viruses is associated with CD4-positive cell decline and progression to AIDS, sugge

26 n immunodeficiency virus-type 1 (HIV-1) on a CD4-positive cell line expressing CCR3 and to a lesser e

27 eath related to HIV-1 infection of the human CD4-positive cell line H9, requires an ICE-like protease

28 hich this antibody blocks HIV-1 entry into a CD4-positive cell.

29 wly and inefficiently adsorbed onto cultured CD4-positive cells at 37 degrees C, and the gradual decl

30 Infection of CD4-positive cells by human immunodeficiency virus type

31 To determine whether specific infection of CD4-positive cells could be demonstrated for these recom

32 Finally, adoptive transfer of CD4-positive cells from GF, but not SPF mice induces sev

33 organs, and in the presentation of virus to CD4-positive cells in multiple locations including lymph

34 HIV-1 is able to infect cultured susceptible CD4-positive cells in standard assay conditions casts do

35 ayed increased numbers of CD25-, FoxP3-, and CD4-positive cells in the CNS.

36 s, there was almost a complete lack of naive CD4-positive cells in the control tumors, a situation th

37 ulovirus powerfully induces proliferation of CD4-positive cells originating from several different sp

38 line produces virions capable of transducing CD4-positive cells with high efficiency (up to 10(5) cel

39 Extensive fusion of CD4-positive cells with the chimeric protein containing

40 CD4-positive cells with TRIM33 knock down show increased

41 lecules were found on the plasma membrane in CD4-positive cells, 43.9 +/- 8.5% were found in CD4-nega

42 e, psi 422, psi 422 cells form syncytia with CD4-positive cells, correctly express HIV-1 structural p

43 nes in stimulating HIV-1 replication in high CD4-positive cells, including primary lymphocytes, but n

44 nalization of CXCR4 in both CD4-negative and CD4-positive cells, suggesting that gp120 is a high affi

45 ated cell-cell fusion and virus infection of CD4-positive cells.

46 kine receptors CCR5 and CXCR4 for entry into CD4-positive cells.

47 ins and can transmit bound virus to adjacent CD4-positive cells.

48 Env cells only upon exposure to soluble CD4, CD4-positive, coreceptor-negative cells, or stromal cell

49 In single-round infections using CD4-positive HeLa cells, the EnvY712A mutation impaired

50 munodeficiency virus (FIV) targets activated CD4-positive helper T cells preferentially, inducing an

51 CD4-positive human CEM-SS T-cell lines were generated wh

52 at IC(90)s, IC(99)s, or IC(> or = 99)s in a CD4-positive human lymphoblastoid cell line (H9 cells) a

53 locked cell fusion and infection with normal CD4-positive human target cells.

54 h leads to the expression of the CD4 gene in CD4-positive hybridoma cells and double-positive thymocy

55 rtantly, TIM-1 inhibits HIV-1 replication in CD4-positive Jurkat cells, despite its capability of up-

56 ion with intracellular localization in human CD4-positive Jurkat T cells.

57 s variants that grow to different extents in CD4-positive leukemic cell lines and that differ only at

58 creased IL-18BP production is a reduction in CD4-positive lymphocyte activation in response to IL-18

59 ral therapy was provided if participants had CD4-positive lymphocyte counts of fewer than 200 cells p

60 ty to cause syncytium formation or fusion in CD4-positive lymphocyte cultures.

61 contribution of these properties to in vivo CD4-positive lymphocyte depletion.

62 lly described between the T-cell receptor of CD4-positive lymphocytes and MHC II on antigen-presentin

63 deficiency virus type 1 (HIV-1) infection of CD4-positive lymphocytes is accompanied by acute cytopat

64 n lead to direct targeting of hepatocytes by CD4-positive lymphocytes, which form an immunologic syna

65 V-1 isolates resulted in the lysis of single CD4-positive lymphocytes.

66 lation and the enhancement of replication in CD4-positive lymphocytes.

67 mal ciliated respiratory epithelia and a CD8/CD4-positive lymphocytic infiltrate that peaked at 21 da

68 numbers of immune cells, including T cells (CD4-positive), macrophages, and mast cells, at all time

69 CD4-positive membrane vesicles (MV) were isolated under

70 s were developed and were shown to express a CD4 positive memory T cell phenotype.

71 These Dsg1-reactive FS T cells exhibited a CD4-positive memory T-cell phenotype and produced a T he

72 ence the development and selection of, e.g., CD4-positive, MHC class II-specific T cells.

73 th IL-15 for 1 week normalizes their hepatic CD4-positive natural killer cell content.

74 these Kupffer cell factors promotes hepatic CD4-positive natural killer cell depletion in ob/ob live

75 vers to lipopolysaccharide, why such hepatic CD4-positive natural killer cell depletion occurs is unc

76 in [IL]-12) or enhance (e.g., IL-15) hepatic CD4-positive natural killer cell viability.

77 tokine production and the hepatic content of CD4-positive natural killer cells were compared in ob/ob

78 The livers of ob/ob mice are depleted of CD4-positive natural killer cells, components of the inn

79 mice and partially replenishes their hepatic CD4-positive natural killer cells.

80 Rather, infection of a CD4-positive precursor cell (CD4 positive/CD8 positive)

81 and replication in several cell lines and in CD4-positive primary lymphocytes.

82 ts of CD4 and replicate more aggressively in CD4-positive primary lymphocytes.

83 ased ratio of these cells to Foxp3-positive, CD4-positive regulatory T cells with sequential therapy.

84 uced tumoral infiltration of neutrophils and CD4 positive T cells, which can be explained by decrease

85 Tumor-reactive CD4-positive T cell clones were isolated from TIL and te

86 s were highly specific and restricted to the CD4-positive T cell population.

87 In the absence of GILT, CD4-positive T cell responses to Der p 1 are significant

88 ith a reduction in the number of circulating CD4-positive T cells (P=0.01), and reduced expression of

89 Activated CD4-positive T cells are essential in the early stages o

90 Since activated CD4-positive T cells are involved in pathogenesis of var

91 l populations, as well as the percentages of CD4-positive T cells expressing IFN-gamma and of NKp46/C

92 We also found that CD4-positive T cells in mice with preexisting immunity t

93 phoid organs, with preferential expansion of CD4-positive T cells in the recipient spleens.

94 and the cytopathicity of virus for infected CD4-positive T cells in this animal model of HIV-1 infec

95 The number of CD4-positive T cells increased by 2.8-fold in MHC I-defi

96 s II and ICAM-1 (ProAd-ICAM) can drive naive CD4-positive T cells into cell cycle, but these T cells

97 to activate Ag-specific Th1 clones and naive CD4-positive T cells isolated from TCR transgenic mice.

98 t on the formation of either mature CD8- and CD4-positive T cells or granulocytes or macrophages, but

99 om patient 888 indicated that they contained CD4-positive T cells that recognized the autologous tumo

100 Dose-dependent inhibition of activated CD4-positive T cells to HIV-1 infection with both bindin

101 ntended to engage and render gluten-specific CD4-positive T cells unresponsive to further antigenic s

102 Previous studies have shown that CD4-positive T cells vary in a predictable manner over 2

103 ionships between cell types like B cells and CD4-positive T cells vary with tissue type.

104 to HIV-1 infection by challenging activated CD4-positive T cells with CCR5-binding and CXCR4-binding

105 rate that was primarily composed of CD3- and CD4-positive T cells, CD20-expressing B cells, macrophag

106 immunodominant epitopes for gluten-specific CD4-positive T cells.

107 s for antigen processing and presentation to CD4-positive T cells.

108 e 1 (HIV-1) infection is the gradual loss of CD4-positive T cells.

109 rment in the activation of these specialized CD4-positive T cells.

110 essed antigens to T cell receptors (TCRs) of CD4-positive T cells.

111 could not replicate in primary A. nancymaae CD4-positive T cells.

112 hey also had increased numbers of glomerular CD4-positive T cells.

113 as F4/80-positive macrophages/microglia and CD4-positive T cells.

114 ntigens from dying cells and present them to CD4-positive T cells.

115 marked decrease in the numbers of activated CD4-positive T cells.

116 C full-length cDNA are infectious in primary CD4-positive T cells.

117 quired for effective antigen presentation to CD4-positive T cells.

118 rogressive increase in their number of naive CD4-positive T cells.

119 issues are enriched in macrophages (MOs) and CD4-positive T cells; however, T helper-type cytokines s

120 Flow cytometric analysis showed that CD4-positive T lymphocyte division was specifically supp

121 lecule (VCAM-1), and MHC class II as well as CD4-positive T lymphocyte infiltration was detected by i

122 The change in percentage of CD4-positive T lymphocytes (CD4%) was investigated in 10

123 essor or cytotoxic subset) predominated over CD4-positive T lymphocytes (helper cells) surrounding th

124 Infection of human CD4-positive T lymphocytes by human immunodeficiency vir

125 creased on mononuclear leukocytes, including CD4-positive T lymphocytes from HIV-positive patients, c

126 ex (MHC) class II-restricted presentation to CD4-positive T lymphocytes occurs after they are interna

127 ion aged 5.7-12.0 weeks with a percentage of CD4-positive T lymphocytes of at least 25% were randomly

128 acterial lipopeptides that are recognized by CD4-positive T lymphocytes of Mycobacterium tuberculosis

129 les, as well as the subsequent activation of CD4-positive T lymphocytes.

130 ass II (MHC II) molecules for recognition by CD4-positive T lymphocytes.

131 ion of nef led to a substantial reduction in CD4-positive T-cell depletion and delayed kinetics of pl

132 lly, relevant doses of Ze-NO induce a dermal CD4-positive T-cell infiltrate and IFN-gamma secretion.

133 detected by reverse transcription-PCR in the CD4-positive T-cell line C8166, but not in peripheral bl

134 , characterised by a T-helper 1 (Th1) biased CD4-positive T-cell response and granuloma formation, fo

135 fection(1-3), but it remains unclear whether CD4-positive T-cell subsets with similar features exist

136 and early CD8-positive cytotoxic T-cell and CD4-positive T-helper cell responses directed toward HIV

137 troviral therapy (HAART) on the evolution of CD4-positive T-lymphocyte (CD4 cell) count among human i

138 s evaluated population- and individual-level CD4-positive T-lymphocyte (CD4 cell) count trajectories

139 with 77 nonusers on age, race, and pre-HAART CD4-positive T-lymphocyte (CD4+ cell) count and viral lo

140 tested semiannually to identify their first CD4-positive T-lymphocyte cell count below 200/microl; t

141 equency of measurement of HIV RNA levels and CD4-positive T-lymphocyte cell counts introduce a possib

142 The annual CD4-positive T-lymphocyte cell decline was less in untre

143 e (p = 0.10), low hemoglobin (p = 0.11), and CD4-positive T-lymphocyte count (p = 0.04).

144 men and how this effect differs depending on CD4-positive T-lymphocyte count.

145 CD4-positive, T-cell-enriched PECs contained only a very

146 to the inhibitory effects of the compound in CD4-positive target cells.

147 to protect against disorders with increased CD4-positive Th1 responses in animals.