ライフサイエンスコーパス: CDR

1 CDR was significantly higher in patients screened with D

2 CDRs predicted to bind the minimal FLAG peptide (Asp-Tyr

3 CDRs represent a unique type of structure that forms tra

4 CDRs were calculated.

5 CDRs were higher with DBT (6.0 per 1000 women screened;

6 For the group with at least 1 CDR of 0.6 or greater, sensitivity of FDT was 66% (95% C

7 f-score: 0.807) and chemicals (BioCreative 5 CDR corpus, NER f-score: 0.914, normalization f-score 0.

8 A complete mutational scan of the 66 CDR residues identified 28 residues as important for the

9 esults build support for ERW deployment as a CDR technique compatible with spreading basalt powder on

10 lementation of screening AB-MR resulted in a CDR of 27.4/1,000 at the patient level after DBT in wome

11 re 69% and 85%, respectively, resulting in a CDR of 59%.

12 re 90% and 91%, respectively, resulting in a CDR of 82%.

13 R, 9-24) observed in countries (N=48) with a CDR ranging from greater than 7.2% but less than or equa

14 face hydrophobic clusters distributed across CDRs of light chains.

15 tical mediators of specificity and affinity, CDRs may also be the primary drivers of biotherapeutic d

16 ain triggers a destabilizing response in all CDR loops in the VL domain and vice versa.

17 in the VL domain are likely to stabilize all CDR loops in the VH domain, and, when these residues are

18 brate the limits of sequence diversity among CDRs that might have a common mode of interaction with p

19 6 points [95% CI, 0.32-0.80]; P < .001), and CDR-Sum of Boxes (mean difference, 0.23 points [95% CI,

20 no significant associations between CCT and CDR, glaucoma, hypertension, and diabetes.

21 showed that both Valpha/Vbeta interface and CDR residues were important in maintaining binding to MA

22 Both RR and CDR remained improved compared with DM for 5 years of DB

23 s in SMA clustered around the N-terminus and CDR loops experience considerable conformational exchang

24 ulation of SHM in both framework regions and CDRs contributed to the clonal affinity and antigenicity

25 buted to ASAP1 control of cell spreading and CDRs.

26 on FAs, cell migration, cell spreading, and CDRs.

27 rived from rare precursors with long anionic CDR H3s that are often deleted in the B cell repertoire.

28 These structurally annotated CDRs provide unprecedented insights into both the struct

29 SCALOP annotates CDR canonical forms for antibody sequences, supported by

30 demonstrated that functional human antibody CDR fusions can be efficiently engineered by grafting th

31 e results illustrate the utility of antibody CDR fusions as a general and effective strategy to gener

32 e results illustrate the utility of antibody CDR fusions as a general and versatile strategy for gene

33 sisting of quinine and reconfigured antibody CDR plays a critical role in recognition of its target e

34 onstrate that arginine mutations in antibody CDRs display context-dependent impacts on specificity an

35 ion involves binding of the drug to antibody CDRs, causing it to acquire specificity for a site on a

36 Among many effects, stabilizing any CDR loop in the VH domain triggers a destabilizing respo

37 ns for specificity were enriched in arginine CDR mutations and displayed low specificity.

38 r specificity were also enriched in arginine CDR mutations, but these antibodies possessed significan

39 ned by the relative contribution of arginine CDR residues to the overall antibody affinity.

40 e hydrophobic environments near the arginine CDR mutations.

41 N-glycosylation sites are clustered around CDRs and the DE loop for both H and L chains, with simil

42 also provides annotated information such as CDR sequences and VDJ genes on the receptors.

43 r(g) >= 0.45; P <= 3.0 x 10(-4)) and between CDR and POAG were high (r(g) = 0.57; P = 2.8 x 10(-10)).

44 here we used single-codon libraries of both CDR and non-CDR residues to generate a deep mutational s

45 Clinical Dementia Rating Scale-Sum of Boxes (CDR-SB; scores range from 0 to 18, with higher scores in

46 nts), Clinical Dementia Rating Sum of Boxes (CDR-Sum of Boxes; 0 [best] to 18 [worst] points), and Lo

47 edit) can mitigate price increases caused by CDR technologies.

48 oportion of firing cells can be increased by CDR of HCN4 to efficiently oppose enhanced responses to

49 designed heavy and light or just heavy chain CDRs were synthesized and screened for peptide binding b

50 s recognition of the Fab HM14c10 light chain CDRs.IMPORTANCE A chimeric yellow fever-dengue live-atte

51 especially concerning for positively charged CDR mutations that are linked to antibody polyspecificit

52 ased use of alleles that encode the critical CDR-H2 Phe54 (F-alleles) to make broadly neutralizing an

53 rgy-biochar systems (BEBCS) can also deliver CDR, they are not included in any IPCC scenario.

54 a Rating [CDR] score, 0) or had AD dementia (CDR score, >0) were included.

55 A combination of different CDR technologies in decentralized biorefinery systems is

56 tions but also mutation pairs from different CDRs that synergistically improve both binding functions

57 n and Vm24-toxin were grafted into different CDRs of the humanized antibodies BVK and Synagis (Syn) u

58 grafting the native hormones into different CDRs of the humanized antibody Herceptin.

59 R-alpha is also clearly capable of eliciting CDRs.

60 g regions (CDRH3s) and variable gene-encoded CDRs.

61 een photograph reading and OCT in estimating CDR.

62 readily interpretable methods for evaluating CDR sequence similarity and then clustering and classify

63 dent on the prescan PSA value with excellent CDR in patients with PSA >= 1 ng/mL.

64 quared distance (RMSD) from the experimental CDR H3 loop structure] than the standard Rosetta energy

65 teractions, and it is unclear to what extent CDRs can accumulate charged residues to increase antibod

66 Unlike the other five CDR loops, CDR H3 does not adopt canonical conformations

67 Five CDRs contact the C5 macroglobulin 7 domain, which contai

68 e was 0.00 (2.60); for MMSE, 29.0 (1.2); for CDR-Sum of Boxes, 0.04 (0.14); and for Logical Memory De

69 trended toward significance, especially for CDRs, but cannot fully explain the observed changes in e

70 sion decreases the number of cells that form CDRs, as well as the area of the CDRs.

71 ction and antigen recognition where germline CDR loop structure has been modified by multiple glycine

72 The difference-from-germline, CDR insertions and/or deletions, similarly occur in uter

73 The fingerprints represent germline, CDR canonical structure, isoelectric point and frequent

74 CDR and noted possible evidence of glaucoma (CDR >/= 0.7 or the presence of a notch or disc hemorrhag

75 We identified 578 participants with a global CDR of 0.5 (i.e. mild cognitive impairment) at baseline,

76 eat potential to help achieve average global CDR goals of 0.5 to 2 gigatonnes of carbon dioxide (CO(2

77 ed by complementarity-determining region H3 (CDR H3).

78 oral epigenetic alterations in hematopoietic CDRs points to sets of genes that are tightly regulated

79 The resulting Herceptin CDR fusion proteins were expressed in good yields in mam

80 The highest CDR was observed with a woman's first DBT examination (6

81 conomic assessment for 2050, quantifying how CDR potential and costs vary among nations in relation t

82 r if affinity mutations in the hypervariable CDRs generally impact antibody stability and to what ext

83 AG and with the severity of abnormalities in CDR and visual field.

84 hat expressed aspartic acid/glutamic acid in CDR L2.

85 e widely accepted function for PDGFR-beta in CDR formation, PDGFR-alpha is also clearly capable of el

86 amining the difference in rates of change in CDR sum of boxes and in all domain scores, participants

87 The difference in CDR estimates between the 2 methods was equal to or grea

88 There was no significant difference in CDR measurement between cameras after adjusting for grad

89 No difference in CDR was evident for the PH or HRL group compared with th

90 stem-directed bnAbs, sequence differences in CDR H3 junctional regions during VDJ recombination can a

91 ograph reading by clinicians agree poorly in CDR assessment.

92 erase 1, we installed O-sulfated tyrosine in CDR H3 of both bNAbs.

93 SAP1 did not rescue NM2A knockdown defect in CDRs.

94 residues in variable domains, especially in CDRs (complementarity determining regions) of an antibod

95 howed lower cognitive performance, increased CDR-SOB, higher amyloid burden and worse clinical progre

96 sion DBT plus synthetic 2D imaging increases CDRs with recall rates comparable to those of FFDM.

97 false-positive (FP) recalls, and incremental CDR for each modality; these were compared using McNemar

98 : 13 tomosynthesis-detected BCs (incremental CDR, 4.0 per 1,000 screens; 95% CI, 1.8 to 6.2) versus 2

99 rsus 23 ultrasound-detected BCs (incremental CDR, 7.1 per 1,000 screens; 95% CI, 4.2 to 10.0), P = .0

100 randomly selected participants with initial CDR less than 0.6.

101 Its CDR is dependent on the prescan PSA value with excellent

102 R), and Chinese Americans showed the largest CDR and disc area after adjusting for age and gender (al

103 We report the patient-level CDR and the positive predictive value of AB-MR examinati

104 The mean real-life CDR of PERFORMS outliers was 7.2 per 1000 women screened

105 er readers (nonoutliers) where the real-life CDR was 7.9 (P = .002).

106 The real-life CDR, recall rate, and PPV of outliers were compared agai

107 BSIS real-life CDRs, recall rates, and PPVs showed positive correlation

108 of influenza haemagglutinin (HA) via a long CDR H3.

109 These mAbs inserted long CDR-H3 loops into the NA active site, engaging residues

110 existing methods, while the remaining loop (CDR H3) remains a challenge due to its highly diverse se

111 Unlike the other five CDR loops, CDR H3 does not adopt canonical conformations and must b

112 his model assumes that if countries with low CDRs increased their rates of caesarean delivery to grea

113 o in (b) less expected results such as lower CDR distances and compactness as well as alteration in t

114 Two masked readers measured CDR and noted possible evidence of glaucoma (CDR >/= 0.7

115 made great strides, but accurately modeling CDR H3 loops remains elusive.

116 due distances for discriminating near-native CDR H3 loops.

117 the heavy chain but no drug conjugation near CDRs of light chain (Lc) from lysine conjugated T-DM1.

118 , we diversified the grafted and neighboring CDR sites using focused mutagenesis to sample each WT or

119 produced by RosettaAntibody and predict new CDR H3 loop structures de novo.

120 Non-CDR residues included those at the interface of the TCR

121 found that the proline at position 41, a non-CDR residue in heavy chain variable regions (VH), is imp

122 d single-codon libraries of both CDR and non-CDR residues to generate a deep mutational scan of a hum

123 insertion of a full-length protein into non-CDR loops of antibodies provides a feasible approach to

124 chain 1 in contrast to the commonly observed CDR heavy chain 3, providing a unique perspective into a

125 Furthermore, the absence of CDR leads to inappropriately enhanced heart rate respons

126 predictor would facilitate the annotation of CDR structures in the large amounts of repertoire data n

127 ences have implicated the high dependence of CDR on tumor genomic and transcriptomic profiles of indi

128 omass, BEBCS may allow earlier deployment of CDR at lower carbon prices when long-term improvements i

129 ires use the highest number and diversity of CDR structures and these patterns of naive repertoire pa

130 Precise identification of CDR is crucial in both guiding anti-cancer drug design a

131 When applied to de novo prediction of CDR H3 loop structures, DeepH3 achieves an average RMSD

132 The regulation of CDR area by RhoG is independent of Rac1 function.

133 ctor, Trio, play a role in the regulation of CDR dynamics, particularly by modulating their size.

134 ion, we provide evidence for a novel role of CDR of HCN4 for the central pacemaker process in the sin

135 ed B-cells are more personalized in terms of CDR structure usage.

136 yeast display to enrich for C05 variants of CDR H3 that bind to H1 and H3 HAs.

137 g and solubility to residues at the edges of CDRs, and provide guidelines for designing other grafted

138 The formation of CDRs involves a drastic rearrangement of the cytoskeleto

139 8852 binds through a coordinated movement of CDRs to a highly conserved epitope encompassing a hydrop

140 l a novel role for RhoG in the regulation of CDRs and the cellular processes associated with their fo

141 Effect of camera modality on CDR measurement; inter- and intraobserver agreement for

142 M2A rescued the effect of ASAP1 knockdown on CDRs but ASAP1 did not rescue NM2A knockdown defect in C

143 pe gullying, whereas the other involved only CDRs, with CDR3 restructuring to wedge in between opposi

144 tio (CDR) >0.8 (23.8% vs. 30.4%, P = .57) or CDR progression of >=0.2 (42.9% vs 44.6%, P = .89, respe

145 male sex, and higher IOP but not glaucoma or CDR.

146 Somatic hypermutation in the other CDRs of PGT145 were crucially involved in stabilizing th

147 ssion and drug response of CCLs, can predict CDR of patients.

148 t preclinical samples can be used to predict CDR of patients and identify biomarkers of drug sensitiv

149 r preclinical samples can be used to predict CDR of real patients.

150 chemical structures of drugs for predicting CDR.

151 tivation of PDGFR-beta homodimers to produce CDRs.

152 n applied to a benchmark set of high-quality CDR H3 loops, the average minimum root mean square devia

153 no differences in the cancer detection rate (CDR) between DM and DBT groups (4.6-5.8 per 1000 examina

154 Results Cancer detection rate (CDR) for DBT plus synthetic 2D imaging was 9.30 per 1000

155 report the prevalent cancer detection rate (CDR) from the first clinical implementation of abbreviat

156 ive value (PPV), and correct detection rate (CDR) of (18)F-rhPSMA-7 PET/CT in biochemical recurrence

157 rate (RR) percentage, cancer detection rate (CDR) per 1000 women screened, false-negative rate per 10

158 The cancer detection rate (CDR) was highest in the BRCA/RT group (26 per 1000 exami

159 per 1000 screens, or cancer detection rate (CDR), 5.1 (95% CI: 5.0, 5.2); sensitivity, 86.9% (95% CI

160 mography recall rate, cancer detection rate (CDR), and positive predictive values (PPVs) for digital

161 ome measures included cancer detection rate (CDR), number of false-positive (FP) recalls, and increme

162 edition and included cancer detection rate (CDR), positive predictive value of biopsy recommendation

163 Cancer detection rate (CDR), recall rate, and positive predictive value (PPV) w

164 ormance (recall rate, cancer detection rate [CDR], and positive predictive value of recall [PPV1]) wa

165 Recall rate, CDR, PPV of positive screening result (PPV1), PPV of bio

166 Conclusion Recall rate, CDR, PPV2, and PPV3 of digital mammography increased aft

167 stigated using the Clinical Dementia Rating (CDR) and the Informant Questionnaire on Cognitive Declin

168 ively normal (CN) (Clinical Dementia Rating [CDR] score, 0) or had AD dementia (CDR score, >0) were i

169 percentages of eyes with cup-to-disc ratio (CDR) >0.8 (23.8% vs. 30.4%, P = .57) or CDR progression

170 To compare cup-to-disc ratio (CDR) measurements from images taken with a portable, 45-

171 48 participants with initial cup-disc ratio (CDR) of 0.6 or greater and 423 images of 360 eyes of 180

172 In the POAG group, optic cup-to-disc ratio (CDR) was positively correlated with deep white matter hy

173 FL thickness and smallest cup-to-disc ratio (CDR), and Chinese Americans showed the largest CDR and d

174 tions with age, sex, IOP, cup-to-disc ratio (CDR), glaucoma, hypertension, and diabetes.

175 resistance factor [CRF], cup-to-disc ratio [CDR], and primary open-angle glaucoma [POAG]).

176 the unsteady convection-diffusion-reaction (CDR) equation, which is classified in mathematics as a l

177 Recommended CDRs were achieved by 92.1% of radiologists in community

178 it to anonymized mobile call detail records (CDRs).

179 considered when making conclusions regarding CDRs in clinical practice.

180 ally acquired myeloid common deleted region (CDR) on chromosome 20q that deleted the second PIGT alle

181 reby the complementarity-determining region (CDR) 3beta loop surrounded and projected into the F'-poc

182 de novo complementarity determining region (CDR) design to engineer targeted antibody-antigen intera

183 nized by complementarity-determining region (CDR) grafting and framework fine tuning and again co-cry

184 elusive complementarity determining region (CDR) H3 loop.

185 vy chain complementarity determining region (CDR) H3 loop.

186 h a long complementarity-determining region (CDR) H3, and competes with the angiotensin-converting en

187 upported complementarily determining region (CDR) loop conformation were identified.

188 Complementarity determining region (CDR) loop flexibility has been suggested to play an impo

189 -encoded complementarity-determining region (CDR) loops 1 and 2, whereas peptide selectivity is guide

190 all six complementarity-determining region (CDR) loops of their paired ValphaVbeta module to recogni

191 of the two complementary determining region (CDR) methionine residues had little or no impact on anti

192 ultralong complementary-determining region (CDR) of a bovine antibody.

193 residue, complementarity-determining region (CDR)-H3 segments.

194 B4 using complementarity-determining region (CDR)-restricted mutagenesis and tailored selection and s

195 n in its complementarity determining region (CDR).

196 in third complementarity-determining region (CDR-H3) antibodies in the antigen-experienced repertoire

197 in third complementarity-determining region (CDR-L3) amino acid sequences and/or Vkappa,lambda-Jkappa

198 binding complementarity determining regions (CDR) compared to the framework regions (FW).

199 within complementarity-determining regions (CDR) induce rich behavior in dynamic response.

200 AT/IMGT complementarity determining regions (CDR) into a human IgG germline framework.

201 entify 32,662 chromatin determinant regions (CDRs), genomic regions with different epigenetic charact

202 oops of complementarity-determining regions (CDRs) 1 and 2.

203 in the complementarity-determining regions (CDRs) are especially important because they can impair t

204 the Ab complementarity determining regions (CDRs) but also surprisingly high in the framework region

205 age and complementarity-determining regions (CDRs) classify ~30% of CLL cases into prognostically imp

206 n their complementarity-determining regions (CDRs) during affinity maturation to enhance electrostati

207 on near complementarity-determining regions (CDRs) from the heavy chain but no drug conjugation near

208 binding complementarity determining regions (CDRs) in a single LC-MS/MS experiment.

209 all six complementarity-determining regions (CDRs) in the affinity maturation of an inhibitory antibo

210 nto the complementarity-determining regions (CDRs) of a stable antibody scaffold.

211 of the complementarity determining regions (CDRs) of antibodies is critically important for antibody

212 erize the complementary-determining regions (CDRs) of more than 180 million human and mouse B-cell re

213 nto the complementarity-determining regions (CDRs) of single-domain (VH) antibodies.

214 nges in complementarity-determining regions (CDRs) of the TCR seen in comparison of unliganded and bo

215 h their complementarity-determining regions (CDRs) or framework regions.

216 FW) and complementarity determining regions (CDRs) that increase binding site conformational diversit

217 ntibody complementarity-determining regions (CDRs) were first described in 1987 and have been redefin

218 n their complementarity-determining regions (CDRs) without compromising thermodynamic stability is cr

219 in the complementarity-determining regions (CDRs), as well as N-glycans present on the Fc/2 fragment

220 in the complementarity determining regions (CDRs), can result in the production of an antibody with

221 y chain complementarity determining regions (CDRs), one mAb, MEDI1912-WFL, has been shown to undergo

222 ariable complementarity determining regions (CDRs), particularly the third CDRs (CDR3s) interact with

223 of the complementarity-determining regions (CDRs), the extent and magnitude of surface hydrophobicit

224 of the complementarity determining regions (CDRs), which are most significant for functional selecti

225 tacting complementarity-determining regions (CDRs), with CDR1 and CDR2 encoded by the V segment and C

226 tralong complementarity-determining regions (CDRs).

227 nown as complementarity-determining regions (CDRs).

228 heavy chain complementarity domain regions (CDRs) of HM14c10, while fewer interactions are observed

229 denosine monophosphate-dependent regulation (CDR) of the major pacemaker channel HCN4 in the sinoatri

230 atmospheric carbon dioxide (CO(2)) removal (CDR), which is now necessary to mitigate anthropogenic c

231 is a biogeochemical carbon dioxide removal (CDR) strategy aiming to accelerate natural geological pr

232 -scale deployment of carbon dioxide removal (CDR) technologies.

233 require atmospheric carbon dioxide removal (CDR).

234 ertainty, antibody-antigen docking resamples CDR loop conformations and can use multiple models to re

235 18 months using the Cognitive Drug Research (CDR) and Cambridge Neuropsychological Test Automated Bat

236 Accurate prediction of cancer drug response (CDR) is challenging due to the uncertainty of drug effic

237 Prediction of clinical drug response (CDR) of cancer patients, based on their clinical and mol

238 Circular dorsal ruffles (CDRs) are actin-rich structures that form on the dorsal

239 adhesions (FAs) and circular dorsal ruffles (CDRs), cell spreading and migration.

240 ramatic, actin-rich Circular Dorsal Ruffles (CDRs).

241 individuals (Clinical Dementia Rating scale [CDR] global scores of 0, above cutoff on the modified Mi

242 g affinity and suggests a role for secondary CDR loops in establishing antibody stability.

243 These results support in silico CDR design of antibody specificity as an emerging antibo

244 improved by taking into account simultaneous CDR loops conformation and VH/VL orientation optimisatio

245 throughout the framework and in four of six CDRs in one design and atomic accuracy in the entire Fv

246 anel on Climate Change scenarios assume that CDR within the energy sector would be delivered using bi

247 The CDR equation has been considered analytically intractabl

248 The CDR was 17 per 1000 screening examinations (95% confiden

249 The CDR was 27.4 per 1,000 (13 of 475; 95% CI, 16.1 to 46.3)

250 The CDR was higher for repeat screening with DBT+SM than for

251 The CDR was lower for the FH group compared with the BRCA/RT

252 istopathology-proven cohort was 91%, and the CDR in this subgroup was 73%.

253 /CT in the composite cohort was 88%, and the CDR was 70%.

254 b showed that deamidation of the drug at the CDR leads to a loss of recognition by the antibodies use

255 on all three monoclonal antibodies to be the CDR H3 loop of the Fab region, and show that they all ha

256 and, when these residues are not buried, the CDR loops in the VL domain are also likely to be stabili

257 Our results establish the CDR structure differences in BCR repertoires and have ap

258 f decline in the sum of boxes score from the CDR(R) Dementia Staging Instrument and in five cognitive

259 rption of matter are super-positioned in the CDR equation as sink and source functions, respectively,

260 disc photograph were 1.6% (3 of 180) in the CDR less than 0.6 group and 31.4% (172 of 548) in the CD

261 than 0.6 group and 31.4% (172 of 548) in the CDR of 0.6 or greater group.

262 pecifically, the amino acid mutations in the CDR region of the heavy chain resulted in significantly

263 mean change from baseline to week 104 in the CDR-SB score was 1.65 in the 12-mg group, 2.02 in the 40

264 ubgroups, while significantly increasing the CDR.

265 gA 5I2 is the predominant involvement of the CDR light chain 1 in contrast to the commonly observed C

266 The evaluation on the CDR corpus yields 0.90 precision, 0.24 recall, and 0.38

267 ation, we assess SemRep's performance on the CDR dataset, a standard benchmark corpus annotated with

268 electron microscopy images, showed that the CDR regions of A11 and B12A recognized epitopes on D1 do

269 , HDX-MS and SPR analysis confirmed that the CDR regions of VHH6 interact simultaneously with IL-6 an

270 ndent of the reference standard, whereas the CDR was the percentage of patients who had at least 1 tr

271 y specific chemical modifications within the CDR, hydrogen-deuterium exchange mass spectrometry (HDX

272 the most common degradation pathways in the CDRs of a mAb and identified correlations between chemic

273 f Asp isomerization and Met oxidation in the CDRs of a model monoclonal antibody (mAb1).

274 rapidly assign multiple Xle residues in the CDRs of mAbs.

275 y, half of the key affinity mutations in the CDRs were destabilizing.

276 , positive charge and negative charge in the CDRs, and asymmetry in the net heavy- and light-chain su

277 increased solvent accessible surface of the CDRs of unbound TCR simulations but also in (b) less exp

278 ions in the most hydrophobic portions of the CDRs, whereas the less specific antibodies contained arg

279 s that form CDRs, as well as the area of the CDRs.

280 variable segment and not enriched within the CDRs.

281 These CDR technologies are applied as part of decentralized bi

282 toire displayed unique features in the third CDR of Ig H chains with minor alterations along the immu

283 ining regions (CDRs), particularly the third CDRs (CDR3s) interact with major histocompatibility comp

284 MMR and NMR observed in countries with those CDRs.

285 By mutating all three CDRs of each antibody chain simultaneously, we were able

286 rine antibody, we modified MMGZ01 Fv through CDR grafting and the reconstructed antibody (H3L2) maint

287 -SEE IgEs as conventional antibodies through CDRs or simultaneously as conventional antibodies and as

288 antibodies and as "superantibodies" through CDRs and framework regions to SEEs in SEE-anti-SEE IgE-F

289 uel selling prices increase by 15-45% due to CDR costs.

290 l comorbidity (NPC) score and compared it to CDR, IQCODE, and NPI scores.

291 ng as antigens in the conventional manner to CDRs and as superantigens to framework regions of anti-S

292 In this article, we explore two CDR technologies: soil carbon sequestration (SCS), and c

293 receptor (IL-6R) by using side chains of two CDR residues filling the site I cavities of IL-6, thus m

294 While both sdAbs used CDRs, they also had atypical side-on approaches, with fr

295 Using CDRs as a robust visual readout of early PDGFR signaling

296 ive selection of somatic mutations in the VH CDR and altered VH CDR3 physicochemical properties.

297 le in the cellular functions associated with CDR formation, including macropinocytosis, receptor inte

298 y Rac1 has been consistently associated with CDR formation, whereas the role of other GTPases in this

299 -protein interaction, hotspots grafting with CDR loop swapping is an attractive route to the rational

300 These residues form hydrogen bonds with CDRs of the Ab other than H CDR3.