ライフサイエンスコーパス: CPM

1 CPM also enhanced the DAKD-induced B1R conformational ch

2 CPM identified an opioid abstinence network (p = 0.018),

3 CPM increased B1R affinity for DAKD by approximately 5-f

4 CPM is a predictive tool and a method of identifying net

5 CPM is associated with decreased MCBC incidence but not

6 CPM is no longer cost-effective for patients older than

7 CPM positive allosteric action was independent of enzyme

8 CPM predicted abstinence during treatment, as indicated

9 CPM provides 21.22 mean QALYs compared with 20.93 for su

10 CPM treatment lowered the extraction of seed tannins, ex

11 CPM was induced using a cold water bath, and the pain th

12 CPM were characterised by frequent Wnt/ beta catenin neg

13 CPM with leave-one-out cross-validation was conducted to

14 CPM-107 contains Mg(2) -acetate chains crosslinked into

15 CPM-733-dps is stable and shows no loss of C(2) H(2) ads

16 CPM-99Fe-derived material, denoted CPM-99Fe/C, exhibits

17 CPM-E264Q-mediated activation of B1Rs by bradykinin resu

18 cted to identify factors associated with (1) CPM vs all other treatments combined, (2) CPM vs unilate

19 r patients with coronary artery disease, 168 CPMs for population samples, and 79 models for patients

20 conformational activation of the B1R, and 2) CPM-generated des-Arg-kinin agonist is efficiently deliv

21 1) CPM vs all other treatments combined, (2) CPM vs unilateral mastectomy (UM), and (3) CPM vs breast

22 Once opened by CO(2) , CPM-107 remains in the stable porous state accessible to

23 econd place in the testing phase of the 2019 CPM-RadPath global challenge.

24 CPMs for 31 index conditions, including 215 CPMs for patients with coronary artery disease, 168 CPMs

25 ) CPM vs unilateral mastectomy (UM), and (3) CPM vs breast-conserving surgery (BCS).

26 -7 mins, 95%CI-9,-5), and had lower CPM (-32 CPM, 95%CI-44,-19) and steps per day (-813 steps, 95%CI,

27 Different from MOF-74, CPM-74 is made from homohelical rod packing.

28 ith early-stage breast cancer and received a CPM increased in many states; however, it did not correl

29 with the proportion of women who received a CPM.

30 population are likely not attributable to a CPM-derived decrease in MCBC incidence.

31 vasive early-stage breast cancer underwent a CPM from 2010 to 2012.

32 with surgery, the proportion who underwent a CPM nationally increased between 2004 and 2012 from 3.6%

33 Key observations include (a) CPM results exhibited low temporal variability, (b) fals

34 ective physician-patient communication about CPM is needed to reduce potential overtreatment.

35 n recommendations, level of discussion about CPM, satisfaction with surgical decision making, receipt

36 43) reported no substantial discussion about CPM.

37 toperative complications were observed after CPM and reconstruction, these procedures were associated

38 ho received no recommendation for or against CPM from a surgeon, 148 (19.0%) underwent CPM.

39 that their surgeon did not recommend against CPM but discussed it.

40 port of first-surgeon recommendation against CPM and the extent of discussion about it with 3 outcome

41 First-surgeon recommendation against CPM does not appear to substantively increase patient di

42 % among patients with recommendation against CPM vs 15.1% of others; P = .52) nor to receive surgery

43 % among patients with recommendation against CPM vs 8.3% of others; P = .88).

44 Women who received a recommendation against CPM were not more likely to seek a second opinion (17.1%

45 %) reported a surgeon recommendation against CPM, of whom only 12 (1.9%) underwent CPM, but among the

46 that their first surgeon recommended against CPM and 30.1% (n = 343) reported no substantial discussi

47 for those whose surgeon recommended against CPM with no substantive discussion (14.5%; n = 37).

48 Although CPMs hold promise for supporting sex-specific decision m

49 s of MCBC were significantly decreased among CPM recipients [RR = 0.04 (95% CI: 0.02, 0.09); RD = -24

50 t of total phenols, but higher than in C and CPM wines.

51 rward translational studies between DNIC and CPM, gauged between bench and bedside, are key for the d

52 nserving surgery, unilateral mastectomy, and CPM.

53 Data collected during periods of natural and CPM conditions show that the alternative pathway was sig

54 eventeen (90%) are de novo CPMs, 21 (3%) are CPM recalibrations, and 58 (7%) are CPM adaptations.

55 (3%) are CPM recalibrations, and 58 (7%) are CPM adaptations.

56 As CPM focuses on linear modeling and a purely data-driven

57 ved from patient self-report, categorized as CPM, unilateral mastectomy, or breast conservation surge

58 quantitative sensory testing (QST) to assess CPM levels, pressure-pain thresholds, and pressure-pain

59 re CPM, one was EPM, and six were associated CPM and EPM.

60 Furthermore, the sustained attention CPM is sensitive to within-subject state changes induced

61 te the association between RA and attenuated CPM.

62 ascular endothelial cells, disruption of B1R-CPM heterodimers inhibited B1R-dependent NO production s

63 e synergistic effects of heterometals bestow CPM-200s with the highest CO2 uptake capacity among know

64 Associations between CPM receipt and surgeon recommendations were also evalua

65 and immunosuppression were compared between CPM/EPM patients and control group of transplanted patie

66 s and assumptions of QOL differences between CPM and surveillance patients.

67 k 20% Pt/C in alkaline and acidic media, but CPM-99Fe/C is more durable and methanol-tolerant.

68 (OA) dogs are good translational models, but CPM has not been explored.

69 g the most porous crystalline chalcogenides, CPM-120-ZnGeS (exchanged with Cs(+) ions) also shows rev

70 e created a novel database and characterized CPMs based on the stage of development, population under

71 M were younger than those who did not choose CPM.

72 Postoperatively, women who chose CPM with implant reconstructions were more satisfied wit

73 he superior outcomes observed when comparing CPM recipients with nonrecipients in the general populat

74 Many patients consider CPM, but knowledge about the procedure is low and discus

75 Overall, 1301 (43.9%) patients considered CPM (601 [24.8%] considered it very strongly or strongly

76 e analytic sample, 18.9% strongly considered CPM and 7.6% received it.

77 Of those who strongly considered CPM, 32.2% received CPM, while 45.8% received unilateral

78 with unilateral breast cancer who considered CPM (n = 1140).

79 Many women considered CPM and a substantial number received it, although few h

80 ions, allowing non-expert users to construct CPMs or in general terms circular plots with a non-genom

81 a systematic review for articles containing CPMs for cardiovascular disease published between Januar

82 This database contains CPMs for 31 index conditions, including 215 CPMs for pat

83 consider when counseling women contemplating CPM as part of their breast cancer treatment.

84 ell size in the CPM so that in the corrected CPM, cell size is independent of the cell motility.

85 PM Registry, a comprehensive database of CVD CPMs published from January 1990 to May 2012.

86 Despite conflicting data, CPM rates continue to increase.

87 DNF was positively correlated with the Delta-CPM-task (0.015, 95% CI = 0.01 to 0.03).

88 vealed a significant difference in the Delta-CPM-task between Per3(4/4) and Per3(5/5) genotypes, with

89 2) were negatively correlated with the Delta-CPM-task, while the Delta-BDNF was positively correlated

90 CPM-99Fe-derived material, denoted CPM-99Fe/C, exhibits the best ORR activity, comparable t

91 shown by a series of new materials (denoted CPM-200s) with superior CO2 uptake capacity (up to 207.6

92 wn about the impact of surgeons discouraging CPM on patient care satisfaction or decisions to seek tr

93 tive Analytics and Comparative Effectiveness CPM Registry, a comprehensive database of CVD CPMs publi

94 ly embedded (metallo)porphyrin centers endow CPM-99 with highly desirable properties as precursors fo

95 otomy-induced decrease in polymodal C-fiber (CPM) heat threshold, but transiently prevented the recru

96 K) and 330 cm(3) g(-1) (273 K) at 1 atm for CPM-733-dps (the Co(2) V-BDC form, BDC=1,4-benzenedicarb

97 Choice for CPM was associated with an improvement in breast satisfa

98 t recurrence appeared to drive decisions for CPM although the procedure has not been shown to reduce

99 eness ratio (ICER) of $4,869/QALY gained for CPM.

100 variables included clinical indications for CPM (genetic mutation and/or strong family history), dia

101 tion can also be tuned from -16.4 kJ/mol for CPM-200-Sc/Mg to -79.6 kJ/mol for CPM-200-V/Mg.

102 kJ/mol for CPM-200-Sc/Mg to -79.6 kJ/mol for CPM-200-V/Mg.

103 y dependent on assumptions regarding QOL for CPM versus surveillance strategy.

104 Four cubic zirconium-porphyrin frameworks, CPM-99(H2, Zn, Co, Fe), were synthesized by a molecular-

105 In this age group, CPM proportions for the period from 2010 to 2012 were ov

106 Greater cancer worry predicted who had CPM (P = 0.02).

107 interested in CPM and 12 (10%) of women had CPM at the time of their primary breast cancer surgery.

108 pects of CPM may affect the decision to have CPM and should be addressed when discussing surgical opt

109 important factors in their decision to have CPM.

110 bout how women approach the decision to have CPM.

111 surgical visit and the likelihood of having CPM after the visit differed (P </= 0.001).

112 n rated their perceived likelihood of having CPM and the surgeons rated the appropriateness of CPM.

113 the patient's reported likelihood of having CPM were not significantly different (P = 0.49).

114 We identified CPMs in the Tufts Predictive Analytics and Comparative E

115 RA patients have impaired CPM when compared to pain-free control subjects.

116 aires assessing knowledge of and interest in CPM and associated psychosocial factors.

117 Interest in CPM before surgical visit and the likelihood of having C

118 Interest in CPM is common among women with sporadic breast cancer.

119 chosocial factors that influence interest in CPM.

120 ancer worry (P = 0.03) predicted interest in CPM.

121 n were moderately to extremely interested in CPM and 12 (10%) of women had CPM at the time of their p

122 conducted a field synopsis of sex effects in CPMs for CVD.

123 ent that various surgical options (including CPM) were discussed; also, the women rated their perceiv

124 Among sex-including CPMs, women with heart failure were at lower mortality r

125 research concerning the biology of isolated CPM.

126 lts of mediation analyses suggested that low CPM levels might be attributed, in part, to sleep distur

127 ctivity (-7 mins, 95%CI-9,-5), and had lower CPM (-32 CPM, 95%CI-44,-19) and steps per day (-813 step

128 n-protein interaction of carboxypeptidase M (CPM) and kinin B1 receptor (B1R) enhances B1R signaling

129 odimerizes with membrane carboxypeptidase M (CPM), facilitating receptor signaling via CPM-mediated c

130 ontrol C), cold pre-fermentation maceration (CPM), saignee (S), pre-fermentation heating with extende

131 recently introduced circular proteome maps (CPMs).

132 of contralateral prophylactic mastectomies (CPMs) among patients with invasive unilateral breast can

133 of contralateral prophylactic mastectomies (CPMs) continues to rise, although there is little eviden

134 te of contralateral prophylactic mastectomy (CPM) among women diagnosed as having breast cancer has r

135 rding contralateral prophylactic mastectomy (CPM) among women with sporadic breast cancer.

136 dergo contralateral prophylactic mastectomy (CPM) and breast reconstruction.

137 ds in contralateral prophylactic mastectomy (CPM) and determine whether survival differed for invasiv

138 es of contralateral prophylactic mastectomy (CPM) have increased dramatically, particularly among you

139 that contralateral prophylactic mastectomy (CPM) should be discouraged in patients without an elevat

140 Contralateral prophylactic mastectomy (CPM) use is increasing among women with unilateral breas

141 Specifically, a new material, CPM-33b-Ni without any open metal sites, exhibits the CO

142 Two new materials (CPM-74 and -75, corresponding to MOF-74 and IRMOF-74-II,

143 rtitioned acs) crystalline porous materials (CPM).

144 ce-partitioned crystalline porous materials (CPMs) with exceptional C(2)H(6) uptake capacity and C(2)

145 we can create crystalline porous materials (CPMs) with superior CO(2) uptake capacity.

146 ), the Raven's Colored Progressive Matrices (CPM), and school performance tests.

147 redox activity of coarse particulate matter (CPM), three sampling sites were set up up in the Los Ang

148 The median CPM level was 0.5 kg/cm2 (interquartile range [IQR] -0.1

149 ly localized to the ciliary pocket membrane (CPM) and transported away from this structure on membran

150 M) share a common cardiopharyngeal mesoderm (CPM) origin, however ESM are unusual among striated musc

151 Colorectal Peritoneal metastases (CPM) develop in 15% of colorectal cancers.

152 Controlled pressure method (CPM) testing is a building-specific diagnostic tool for

153 Controlled pressure methods (CPM) have been proposed as an alternative, but temporal

154 copy (AFM)-based colloidal probe microscopy (CPM) method.

155 vel of physical activity (counts per minute [CPM], steps, time spent in light, moderate or vigorous a

156 eviously reported linear change point model (CPM) and locally weighted scatterplot smoothing curves.

157 ell clusters using the Cellular Potts Model (CPM) in a monolayer geometry.

158 attention connectome-based predictive model (CPM), a validated model of sustained attention function,

159 oped a connectome-based predictive modeling (CPM) approach.

160 resent connectome-based predictive modeling (CPM), a data-driven protocol for developing predictive m

161 using connectome-based predictive modeling (CPM), a recently developed machine learning approach.

162 Connectome-based predictive modeling (CPM)-a recently developed, whole-brain approach-was used

163 Clinical prediction models (CPMs) estimate the probability of clinical outcomes and

164 e role of sex in clinical prediction models (CPMs).

165 Conditioned pain modulation (CPM) is the human counterpart of DNIC and requires a des

166 (DPMS) using a conditioned pain modulation (CPM) paradigm according to the variable-number tandem-re

167 Conditioned pain modulation (CPM) testing assesses EPM function.

168 h as diminished conditioned pain modulation (CPM), may play a role in enhancing pain perception among

169 new magnesium metal-organic framework (MOF) (CPM-107) with a special interaction with CO(2) .

170 Moreover, CPM-120-ZnGeS could also function as a robust photocatal

171 Moreover, CPM-74 has high hydrothermal and thermal stability uncom

172 ntral pontine and extrapontine myelinolysis (CPM/EPM) are severe neurologic complications after liver

173 7), but no difference was reported in the no-CPM group in the other QOL domains.

174 Compared with nonrecipients, CPM recipients had higher rates of overall survival [OS;

175 Seven hundred seventeen (90%) are de novo CPMs, 21 (3%) are CPM recalibrations, and 58 (7%) are CP

176 h cardiovascular disease, there are numerous CPMs available although the extent of this literature is

177 .e., slope of approximately 0 after observed CPM change point) was detected for cpRNFL thickness only

178 ), epigenome (n = 24) and genome (n = 21) of CPM and matched primary CRC was performed.

179 nstructive surgery was performed in 48.3% of CPM patients compared with only 16.0% of unilateral mast

180 are important to the biological activity of CPM, and that a more targeted control strategy may be ne

181 Surgeons' rating of the appropriateness of CPM and the patient's reported likelihood of having CPM

182 nd the surgeons rated the appropriateness of CPM.

183 The informational and emotional aspects of CPM may affect the decision to have CPM and should be ad

184 sis were used to evaluate the association of CPM with four BREAST-Q QOL domains.

185 Crustal materials, the major component of CPM, demonstrated very low water-solubility, in contrast

186 In non-BRCA patients, cost-effectiveness of CPM is highly dependent on assumptions regarding QOL for

187 ells inhibited the allosteric enhancement of CPM on B1R DAKD binding or ERK1/2 activation.

188 tably transfected with B1R, co-expression of CPM enhanced DAKD-stimulated increases in intracellular

189 n of the CPM/B1R interaction or knockdown of CPM in cytokine-treated primary human endothelial cells

190 study was undertaken to examine the level of CPM, pressure-pain threshold, and pressure-pain toleranc

191 mpared to identify independent predictors of CPM.

192 n (OR = 1.7) to be independent predictors of CPM.

193 tively evaluated single-center prevalence of CPM/EPM and associated risk factors: cause of liver dise

194 results present distinct diurnal profiles of CPM-induced ROS formation in the two seasons, with much

195 Such peculiar properties of CPM-107 are apparently linked to a convergence of factor

196 The rate of CPM was 13.8% (n = 407), increasing from 6.7% in 1997 to

197 ltivariate regression showed that receipt of CPM (vs either unilateral mastectomy or breast conservat

198 Receipt of CPM was the primary dependent variable for analysis and

199 d a mastectomy and 1,598 reported receipt of CPM.

200 ically, QOL differed according to receipt of CPM.

201 aging at diagnosis contributed to receipt of CPM.

202 The use of CPM more than tripled during the study period despite ev

203 ut the underlying factors driving the use of CPM.

204 an alternative, but temporal variability of CPM results and whether they are indicative of impacts u

205 There is an abundance of CPMs available for a wide assortment of cardiovascular d

206 The number of CPMs published each year is increasing steadily over tim

207 The increase in the proportion of CPMs among women with early-stage unilateral breast canc

208 the temporal trend and in the proportion of CPMs among women with early-stage unilateral breast canc

209 Temporal changes in the proportion of CPMs among women with early-stage unilateral breast canc

210 variation and increasing trend in the use of CPMs.

211 rves for the adsorption of carbon dioxide on CPM-5 (crystalline porous materials) were obtained exper

212 In many respects, the GGH or CPM methodology and the approach of the centre-based mod

213 nserving therapy), unilateral mastectomy, or CPM, with subsequent subgroup analysis stratifying by ag

214 of the lattice-based Cellular Potts Model or CPM (also known as the Glazier-Graner-Hogeweg or GGH mod

215 tain the microcubic morphology of the parent CPM-99 but also possess porphyrinic active sites, hierar

216 onal Precision Medicine Radiology-Pathology (CPM-RadPath) Challenge on Brain Tumor Classification 201

217 For BRCA-positive patients, CPM is clearly cost-effective, providing more QALYs whil

218 currently the only available path to porous CPM-107 which shows efficient C(2) H(2) /CO(2) separatio

219 esent the first meta-analysis to assess post-CPM outcomes in women with UBC.

220 Perifoveal vessel density reached the post-CPM estimated floor later in the disease (VF MD, -25.8+/

221 The post-CPM estimated floors were 49.5+/-2.6 mum for cpRNFL thic

222 hich then led to the formulation of proposed CPM testing guidelines.

223 are included in only one third of published CPMs.

224 ssure difference (or exhaust fan flow rate), CPM test duration, exhaust fan location, and air samplin

225 who strongly considered CPM, 32.2% received CPM, while 45.8% received unilateral mastectomy and 22.8

226 1.2%) underwent UM, and 428 (17.3%) received CPM.

227 he majority of patients (68.9%) who received CPM had no major genetic or familial risk factors for co

228 Soluble, recombinant CPM bound to HEK cells expressing B1Rs without stimulati

229 re chief determinants in decisions regarding CPM.

230 Of 592 CVD-related CPMs, 193 (33%) included sex as a predictor or presented

231 in selected patients with limited resectable CPM.

232 yet surpassed peroxo-MOF-74-Fe, these robust CPMs exhibit outstanding properties including high therm

233 bers of women with breast cancer are seeking CPM.

234 Here, we show CPM is also a positive allosteric modulator of B1R signa

235 Among them, highly stable CPM-120-ZnGeS allows for ion exchange with diverse metal

236 his study is the first involving a long-term CPM test at a house having a multiyear high temporal res

237 The tested CPM-5 showed an outstanding adsorption equilibrium capac

238 ates how controlled-pressure-method testing (CPM), soil gas sampling, and screening-level emissions c

239 We hypothesized that CPM testing would demonstrate EPM impairment in OA dogs

240 trongly); only 395 (38.1%) of them knew that CPM does not improve survival for all women with breast

241 Despite knowing that CPM does not clearly improve survival, women who have th

242 The results suggest that CPM tests should be conducted with both negative and pos

243 On multivariable analysis, the CPM group continued to report higher breast satisfaction

244 lating the building pressure conditions, the CPM creates the worst-case VI impact and provides rapid

245 age 45 years are comparable: $36,594 for the CPM and $35,182 for surveillance.

246 However, the CPM construction requires prior data transformation and

247 , mean breast satisfaction was higher in the CPM group (60.4 v 57.9, P < .001) and mean physical well

248 nd mean physical well-being was lower in the CPM group (74.6 v 76.6, P < .001).

249 were not significantly more frequent in the CPM group than in the group of women who did not undergo

250 motility-induced changes in cell size in the CPM so that in the corrected CPM, cell size is independe

251 This is an artifact in the CPM.

252 th finding either malignancy or a HRL in the CPM.

253 An analysis of the CPM reveals an explicit inverse-relationship between the

254 ure regardless of day or time of year of the CPM test.

255 Some members of the CPM-200s family consist of combinations of metal ions (e

256 Disruption of the CPM/B1R interaction or knockdown of CPM in cytokine-trea

257 ressibility within the CPM and find that the CPM predicts that increased cell motility leads to small

258 It has been demonstrated that the CPM protocol performs as well as or better than many of

259 It was found that the CPM-5 has a dynamic CO2 adsorption capacity of 11.9 wt %

260 Thus, the CPM results were a reliable indicator of VI occurrence a

261 measurement steps from normal values to the CPM estimated floor was greatest for cpRNFL thickness (8

262 cell motility and compressibility within the CPM and find that the CPM predicts that increased cell m

263 t of adsorption (21.9-30.4 kJ/mol) for these CPMs is as low as about one-third of that for peroxo-MOF

264 Thus, CPM binding to extracellular loop 2 of the B1R results i

265 R signaling in two ways; 1) kinin binding to CPM causes a conformational activation of the B1R, and 2

266 ctivities, despite their low contribution to CPM mass, are important to the biological activity of CP

267 sociated with transition from primary CRC to CPM and of patients with CPM not responding to treatment

268 2-hydroxyterephthalic acid), which leads to CPM-74, Zn(2)(OH)(obdc), that is nearly isomeric with MO

269 o protect the public health from these toxic CPM sources.

270 Among 997 transplants, CPM/EPM were diagnosed in 11 patients (1.1%), of whom fo

271 natural conditions; it was identified under CPM conditions when measured emission rates were 2 order

272 an in the group of women who did not undergo CPM (14 of 86 [16.3%] vs 113 of 848 [13.3%], P = .43).

273 Patients who did and did not undergo CPM within 1 year of treatment for their index cancer we

274 8%], P = .01) than those who did not undergo CPM.

275 t known FGR should not be advised to undergo CPM.

276 ed that women with breast cancer who undergo CPM live longer than those who do not.

277 provement in BCSS or OS for women undergoing CPM (BCSS: HR 1.08, 95% confidence interval 1.01-1.16; O

278 Overall, the proportion of women undergoing CPM increased from 3.9% in 2002 to 12.7% in 2012 (P < 0.

279 Women undergoing CPM were younger than those who did not choose CPM.

280 nt unilateral mastectomy, and 7.0% underwent CPM.

281 st CPM from a surgeon, 148 (19.0%) underwent CPM.

282 gainst CPM, of whom only 12 (1.9%) underwent CPM, but among the 746 (46.8%) of these women who receiv

283 Eighty-six of the 934 (9.2%) women underwent CPM and were more likely to be younger (mean age, 48 yea

284 irment in OA dogs compared to controls using CPM.

285 Previously using CPM, we defined a high-attention network, comprising con

286 M (CPM), facilitating receptor signaling via CPM-mediated conversion of bradykinin or kallidin to des

287 VM CPM was lower in children with PAH (n = 29) than in cont

288 In post hoc analyses, VM CPM and time spent in moderate/vigorous combined and vig

289 Vector magnitude counts per minute (VM CPM) and time per day spent in different PA intensity le

290 sed in 11 patients (1.1%), of whom four were CPM, one was EPM, and six were associated CPM and EPM.

291 show the molecular features associated with CPM development and associated with not responding to CR

292 sis can be found isolated or associated with CPM in up to two of three liver transplanted patients wi

293 tivariable analysis, factors associated with CPM included younger age (per 5-year increase: odds rati

294 r of MR imaging lesions for association with CPM by using the Fisher exact test, exact chi(2) test, a

295 Patients undergoing mastectomy with CPM for their first diagnosis of unilateral stage 0 to I

296 from primary CRC to CPM and of patients with CPM not responding to treatment with CRS & HIPEC, to ide

297 A cohort of patients with CPM treated with CRS & HIPEC was recruited and divided a

298 rt improvement in quality of life (QOL) with CPM.

299 patients, with rates of reconstruction with CPM rising from 35.3% in 2002 to 55.4% in 2012 (P < 0.00

300 work to interpret pathologies arising within CPM derivatives.